Nek8

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	PL	gene expression	Nek8	0.13	0.1	1.1e-13	0.1	0.13	0.12	0.12	3.0e-11	4.0e-14	1.6e-12	1.7e-13
2	BLA	gene expression	Nek8	0.08	0.07	4.4e-04	0.03	0.04	0.04	0.04	9.0e-03	2.9e-03	3.3e-03	3.9e-03
3	IC	gene expression	Nek8	0.12	0.1	2.6e-04	0.05	0.07	0.04	0.06	3.2e-03	7.1e-04	6.3e-03	1.2e-03
4	RMTg	alternative polyA	NM_001105804.2	0.1	0.09	6.4e-03	0.09	0.1	0.09	0.08	2.1e-03	1.6e-03	1.8e-03	3.1e-03
5	NAcc	gene expression	Nek8	0.1	0.07	0.0e+00	0.11	0.12	0.11	0.12	9.6e-17	1.2e-17	3.1e-16	1.7e-17
6	IL	gene expression	Nek8	0.22	0.18	1.6e-04	0.11	0.16	0.1	0.17	1.3e-03	1.0e-04	1.8e-03	6.1e-05
7	Brain	gene expression	Nek8	0.1	0.07	5.9e-10	0.11	0.1	0.11	0.1	2.3e-10	5.2e-10	4.2e-10	9.9e-10
8	pVTA	gene expression	Nek8	0.16	0.12	7.1e-12	0.12	0.14	0.14	0.13	1.6e-09	3.8e-11	3.4e-11	7.2e-11
9	LHb	gene expression	Nek8	0.23	0.19	1.5e-04	0.1	0.15	0.17	0.14	2.5e-03	2.3e-04	6.3e-05	2.9e-04
10	Adipose	gene expression	Nek8	0.02	0.02	6.8e-03	0.01	0	0	0	3.3e-02	1.2e-01	1.0e-01	1.0e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10
Bone: apparent density	2.1	3.9	4.1	1.9	2.0	2.0	-2.0	2.0	2.0	-2.0	-2.0	-2.0	-2.0
Area under the delay curve	1.7	2.7	3.2	-1.3	-1.5	-1.6	1.6	-1.6	-1.7	1.6	1.7	1.7	1.8
BMI with tail	1.7	5.9	6.5	2.5	2.5	2.4	-2.5	2.5	2.3	-2.4	-2.4	-2.4	-2.3
BMI without tail	1.2	6.6	7.1	2.5	2.6	2.6	-2.6	2.6	2.5	-2.6	-2.6	-2.7	-2.3
Body weight	2.5	11.0	12.4	3.5	3.5	3.4	-3.4	3.4	3.3	-3.2	-3.3	-3.3	-2.8
Weight adjusted by age	0.1	0.2	0.5	0.3	0.4	0.4	-0.4	0.4	0.5	-0.2	-0.5	-0.5	-0.7
Bone surface	1.5	3.0	3.4	1.7	1.7	1.7	-1.7	1.7	1.7	-1.8	-1.8	-1.8	-1.7
Bone volume	1.3	2.6	2.7	1.6	1.6	1.6	-1.6	1.6	1.6	-1.6	-1.6	-1.6	-1.6
Breakpoint value in progressive ratio session	0.4	0.8	1.1	0.7	0.8	0.9	-0.9	0.9	1.0	-0.7	-0.9	-1.0	-0.9
Number of licking bursts	0.1	0.4	0.4	-0.7	-0.6	-0.6	0.6	-0.6	-0.5	0.5	0.6	0.6	0.6
Context. condit. distance diff. score	0.6	0.7	0.8	0.9	0.8	0.8	-0.8	0.8	0.8	-0.8	-0.8	-0.8	-0.9
Locomotion velocity, session 1	2.0	2.3	2.5	1.6	1.6	1.5	-1.5	1.5	1.5	-1.4	-1.5	-1.5	-1.4
Locomotion distance, session 1	0.2	0.3	0.4	0.6	0.6	0.5	-0.5	0.5	0.5	-0.3	-0.5	-0.6	-0.2
Locomotion velocity, session 2	0.0	0.0	0.1	0.2	0.2	0.2	-0.2	0.2	0.2	-0.1	-0.2	-0.3	-0.2
Locomotion distance, session 2	1.2	1.6	1.7	1.3	1.3	1.3	-1.3	1.3	1.3	-1.3	-1.3	-1.3	-1.3
Locomotion velocity, session 3	3.1	3.6	4.1	-2.0	-2.0	-1.9	1.9	-1.9	-1.9	1.7	1.9	1.9	1.7
Locomotion distance, session 3	0.4	0.5	0.6	-0.7	-0.7	-0.7	0.7	-0.7	-0.7	0.7	0.7	0.7	0.8
Stereotopy head waving bouts, day 3	0.0	0.0	0.1	0.0	0.1	0.1	-0.1	0.1	0.2	-0.3	-0.2	-0.2	-0.3
Stereotopy head waving duration, day 3	0.3	0.4	0.7	-0.9	-0.7	-0.6	0.6	-0.6	-0.5	0.3	0.5	0.5	0.4
Locomotion velocity, session 7	0.4	0.4	0.6	0.5	0.6	0.6	-0.6	0.6	0.7	-0.8	-0.7	-0.7	-0.7
Locomotion distance, session 7	0.5	0.7	0.7	0.7	0.8	0.8	-0.8	0.8	0.8	-0.8	-0.8	-0.9	-0.7
Stereotopy head waving bouts, day 7	0.6	0.6	0.9	0.7	0.8	0.8	-0.8	0.8	0.8	-0.9	-0.8	-0.8	-1.0
Stereotopy head waving duration, day 7	0.3	0.4	0.5	0.5	0.5	0.6	-0.6	0.6	0.6	-0.7	-0.6	-0.6	-0.7
Locomotion velocity, session 8	0.0	0.0	0.0	0.2	0.2	0.1	-0.1	0.1	0.1	-0.2	-0.1	-0.1	-0.0
Locomotion distance, session 8	0.8	1.2	1.2	1.1	1.1	1.1	-1.1	1.1	1.1	-1.0	-1.1	-1.1	-1.1
Degree of sensitization distance	3.2	3.5	3.6	1.8	1.9	1.9	-1.9	1.9	1.9	-1.9	-1.9	-1.9	-1.8
Degree of sensitization stereotypy	0.6	0.7	0.9	0.8	0.8	0.8	-0.8	0.8	0.8	-0.8	-0.8	-0.8	-1.0
Conditioned locomotion	1.4	1.6	2.1	-1.5	-1.4	-1.3	1.3	-1.3	-1.2	1.1	1.3	1.2	1.1
Cocaine response after cond. corrected	1.3	1.9	2.2	1.4	1.4	1.4	-1.4	1.4	1.4	-1.4	-1.3	-1.3	-1.5
Cocaine response after cond. not corrected	1.8	2.6	2.9	1.6	1.6	1.6	-1.6	1.6	1.6	-1.7	-1.5	-1.5	-1.7
Cocaine response before conditioning	0.2	0.3	0.3	0.5	0.5	0.5	-0.5	0.5	0.5	-0.6	-0.5	-0.5	-0.4
Saline control response	0.0	0.0	0.1	-0.1	-0.0	-0.0	0.0	-0.0	-0.1	-0.2	-0.1	0.0	-0.2
Bone: connectivity density	4.0	6.4	7.1	2.4	2.5	2.5	-2.5	2.5	2.5	-2.6	-2.6	-2.5	-2.7
Bone: cortical apparent density	0.3	0.5	0.7	-0.8	-0.8	-0.7	0.7	-0.7	-0.7	0.6	0.7	0.7	0.7
Bone: cortical area	1.5	2.4	3.1	-1.5	-1.5	-1.5	1.5	-1.5	-1.5	1.6	1.6	1.5	1.8
Bone: cortical porosity	0.3	0.3	0.5	0.5	0.6	0.6	-0.6	0.6	0.5	-0.7	-0.6	-0.6	-0.6
Bone: cortical porosity	0.1	0.1	0.2	0.3	0.4	0.4	-0.4	0.4	0.3	-0.5	-0.4	-0.4	-0.4
Bone: cortical thickness	2.8	4.6	5.0	-2.2	-2.2	-2.1	2.1	-2.1	-2.0	2.2	2.2	2.1	2.2
Bone: cortical thickness	0.0	0.0	0.0	-0.2	-0.2	-0.1	0.1	-0.1	-0.1	0.1	0.1	0.1	0.1
Bone: cortical tissue density	0.2	0.3	0.4	-0.6	-0.6	-0.5	0.5	-0.5	-0.5	0.4	0.5	0.5	0.5
Condit. Reinf. active minus inactive responses	0.6	0.7	0.9	-0.9	-0.9	-0.9	0.9	-0.9	-0.8	0.8	0.8	0.8	0.8
Condit. Reinf. active-inactive response ratio	0.2	0.2	0.2	-0.4	-0.4	-0.4	0.4	-0.4	-0.4	0.4	0.4	0.4	0.4
Condit. Reinf. active responses	0.0	0.0	0.0	-0.2	-0.1	-0.1	0.1	-0.1	-0.1	0.1	0.1	0.1	0.0
Condit. Reinf. inactive responses	0.3	0.4	0.5	0.6	0.6	0.6	-0.6	0.6	0.6	-0.6	-0.6	-0.6	-0.7
Incentive salience index mean	0.2	0.3	0.4	-0.6	-0.6	-0.6	0.6	-0.6	-0.6	0.5	0.6	0.6	0.4
Condit. Reinf. lever presses	0.1	0.1	0.2	0.3	0.3	0.3	-0.3	0.3	0.3	-0.4	-0.3	-0.3	-0.5
Condit. Reinf. active minus inactive responses	0.2	0.3	0.6	-0.8	-0.7	-0.5	0.6	-0.6	-0.5	0.4	0.5	0.4	0.4
Condit. Reinf. active-inactive response ratio	0.4	0.6	0.8	-0.9	-0.8	-0.8	0.8	-0.8	-0.8	0.6	0.7	0.7	0.6
Condit. Reinf. active responses	0.1	0.2	0.4	-0.6	-0.5	-0.4	0.4	-0.4	-0.3	0.3	0.3	0.3	0.3
Condit. Reinf. inactive responses	0.0	0.1	0.1	0.1	0.2	0.2	-0.2	0.2	0.4	-0.2	-0.2	-0.3	-0.2
Condit. Reinf. lever presses	2.3	3.3	3.7	-1.9	-1.9	-1.8	1.9	-1.8	-1.9	1.8	1.8	1.8	1.7
Condit. Reinf. lever reinforcers received	0.3	0.5	0.8	-0.9	-0.8	-0.7	0.7	-0.7	-0.6	0.6	0.6	0.6	0.6
Conditioned reinforcement - actives	0.1	0.4	0.6	0.6	0.6	0.6	-0.6	0.6	0.5	-0.7	-0.6	-0.5	-0.8
Conditioned reinforcement - inactives	0.0	0.1	0.2	0.5	0.4	0.3	-0.3	0.3	0.3	-0.1	-0.2	-0.3	-0.1
Conditioned locomotion	0.2	0.3	0.7	0.7	0.6	0.5	-0.5	0.5	0.3	-0.6	-0.4	-0.3	-0.8
Patch foraging indifference point 0 sec	0.2	0.7	1.1	-0.9	-0.8	-0.8	0.8	-0.8	-0.7	1.1	0.8	0.6	0.8
Patch foraging indifference point AUC	1.2	2.8	3.3	-1.8	-1.8	-1.8	1.8	-1.8	-1.8	1.3	1.7	1.8	1.3
Delay disc. indifference point, 0s delay	1.0	1.1	1.8	-0.8	-0.9	-1.0	1.0	-1.0	-1.1	1.0	1.1	1.1	1.4
Delay disc. indifference point, 16s delay	1.4	2.0	2.8	-1.0	-1.2	-1.4	1.4	-1.4	-1.5	1.6	1.5	1.5	1.7
Delay disc. indifference point, 2s delay	2.7	3.0	3.3	-1.6	-1.7	-1.8	1.8	-1.8	-1.7	1.6	1.7	1.7	1.8
Delay disc. indifference point, 24s delay	0.5	0.7	1.2	0.9	0.8	0.8	-0.8	0.8	0.8	-1.1	-0.8	-0.8	-0.9
Delay disc. indifference point, 4s delay	0.3	0.3	0.6	-0.3	-0.5	-0.5	0.5	-0.5	-0.6	0.6	0.6	0.6	0.8
Delay disc. indifference point, 8s delay	0.8	1.3	1.8	-0.9	-1.1	-1.2	1.2	-1.2	-1.3	1.0	1.2	1.4	0.9
Indifference point function ln k	0.3	0.8	1.1	0.9	1.0	1.0	-1.0	1.0	1.0	-0.4	-1.0	-1.1	-0.5
Indifference point function log k	0.3	0.8	1.1	0.9	1.0	1.0	-1.0	1.0	1.0	-0.4	-1.0	-1.1	-0.5
Patch foraging total patch changes 0 sec	0.2	0.5	0.9	-0.8	-0.7	-0.7	0.7	-0.7	-0.6	0.9	0.7	0.5	0.7
Patch foraging total patch changes 12 sec	0.2	0.3	0.4	-0.5	-0.5	-0.5	0.5	-0.5	-0.5	0.6	0.5	0.5	0.5
Patch foraging total patch changes 18 sec	1.0	2.3	2.6	-1.6	-1.6	-1.5	1.5	-1.5	-1.4	1.6	1.5	1.4	1.5
Patch foraging total patch changes 24 sec	0.8	2.9	3.5	-1.9	-1.8	-1.7	1.7	-1.7	-1.7	1.6	1.7	1.6	1.4
Patch foraging total patch changes 6 sec	3.0	5.1	5.3	-2.3	-2.3	-2.3	2.3	-2.3	-2.3	2.1	2.3	2.3	2.1
Patch foraging time to switch 0 sec	0.6	2.4	2.7	1.6	1.6	1.5	-1.5	1.5	1.5	-1.6	-1.5	-1.4	-1.5
Patch foraging water rate 0 sec	0.8	3.0	3.6	-1.8	-1.7	-1.7	1.7	-1.7	-1.7	1.9	1.6	1.6	1.8
Patch foraging water rate 12 sec	0.1	0.3	0.7	0.5	0.6	0.6	-0.6	0.6	0.6	-0.2	-0.6	-0.8	-0.3
Patch foraging water rate 18 sec	0.3	0.6	0.7	0.9	0.8	0.8	-0.8	0.8	0.8	-0.5	-0.8	-0.8	-0.6
Patch foraging water rate 24 sec	0.2	0.3	0.7	-0.4	-0.5	-0.5	0.5	-0.5	-0.5	0.8	0.5	0.5	0.9
Patch foraging water rate 6 sec	1.0	1.5	2.0	-1.3	-1.2	-1.2	1.2	-1.2	-1.1	1.4	1.1	1.1	1.4
Seeking ratio, delayed vs. immediate footshock	1.8	2.5	3.3	-1.5	-1.6	-1.6	1.6	-1.6	-1.6	1.5	1.6	1.8	1.4
Distance traveled before self-admin	2.0	4.4	4.8	-2.2	-2.2	-2.2	2.2	-2.2	-2.2	1.8	2.1	2.1	1.9
Distance traveled after self-admin	0.1	0.1	0.1	-0.3	-0.3	-0.3	0.3	-0.3	-0.4	0.1	0.4	0.3	0.2
Extensor digitorum longus weight	0.7	2.8	3.2	1.8	1.7	1.7	-1.7	1.7	1.7	-1.6	-1.7	-1.6	-1.6
Bone: elastic displacement	2.8	3.5	3.7	-1.9	-1.9	-1.9	1.9	-1.9	-1.9	1.9	1.8	1.8	1.9
Bone: elastic work	8.6	11.3	12.7	-3.4	-3.3	-3.3	3.3	-3.3	-3.2	3.6	3.3	3.2	3.6
Bone: endosteal estimation	0.0	0.0	0.1	0.0	-0.1	-0.1	0.1	-0.1	-0.2	0.2	0.1	0.1	0.3
Bone: endosteal perimeter	0.0	0.0	0.0	0.2	0.1	0.0	-0.0	0.0	-0.0	0.0	-0.0	-0.0	0.2
Epididymis fat weight	5.2	26.4	29.4	5.4	5.3	5.2	-5.2	5.2	5.1	-5.0	-5.1	-5.0	-4.7
Delta time in closed arm before/after self-admin	2.9	2.8	3.0	-1.7	-1.7	-1.7	1.7	-1.7	-1.6	1.6	1.7	1.6	1.6
Delta time in open arm before/after self-admin	5.1	6.0	6.8	2.6	2.5	2.4	-2.4	2.4	2.3	-2.6	-2.4	-2.3	-2.5
Diff in mean of infusions in LGA sessions	0.4	0.7	0.7	0.8	0.8	0.8	-0.8	0.8	0.8	-0.8	-0.8	-0.8	-0.7
Delay discount exponential model param	1.3	1.8	2.1	1.0	1.2	1.4	-1.3	1.3	1.4	-1.3	-1.4	-1.4	-1.4
Extinction: sum of active levers before priming	0.8	1.2	1.4	1.0	1.1	1.1	-1.1	1.1	1.2	-1.1	-1.1	-1.1	-1.2
Active lever presses in extinction session 6	0.4	0.4	0.8	0.4	0.5	0.7	-0.6	0.7	0.8	-0.6	-0.8	-0.9	-0.7
Bone: final force	0.4	0.6	0.8	-0.7	-0.7	-0.7	0.7	-0.7	-0.8	0.8	0.8	0.8	0.9
Bone: final moment	0.4	0.7	0.9	-0.7	-0.8	-0.8	0.8	-0.8	-0.8	0.9	0.8	0.8	1.0
Food consumed during 24 hour testing period	0.1	0.2	0.4	-0.5	-0.4	-0.4	0.4	-0.4	-0.3	0.6	0.3	0.2	0.5
Glucose	1.4	2.3	2.5	-1.5	-1.5	-1.5	1.5	-1.5	-1.6	1.4	1.5	1.6	1.2
Heart weight	1.6	2.6	3.1	1.5	1.6	1.7	-1.7	1.7	1.8	-1.3	-1.6	-1.7	-1.3
Delay discount hyperbolic model param	1.8	2.3	2.7	1.3	1.4	1.5	-1.5	1.5	1.6	-1.5	-1.5	-1.5	-1.6
Intermittent access intake day 1-15 change	0.0	0.1	0.5	0.2	0.2	0.2	-0.2	0.2	0.1	-0.6	-0.3	-0.2	-0.7
Intermittent access intake escalation	0.0	0.2	0.6	0.4	0.3	0.3	-0.3	0.3	0.2	-0.7	-0.4	-0.3	-0.8
Intermittent access intake escalation 2	0.1	0.2	0.3	-0.4	-0.4	-0.4	0.4	-0.4	-0.5	0.0	0.4	0.5	-0.0
Intermitt. access day 1 inactive lever presses	0.0	0.2	0.2	-0.4	-0.4	-0.4	0.4	-0.4	-0.4	0.4	0.4	0.4	0.5
Intermitt. access day 15 inactive lever presses	0.1	0.6	0.7	-0.8	-0.8	-0.8	0.8	-0.8	-0.8	0.8	0.8	0.7	0.8
Intermitt. access escalation Index	0.3	0.9	1.4	1.2	1.1	1.0	-1.0	1.0	0.9	-0.7	-1.0	-0.9	-0.8
Intermittent access day 1 total infusions	0.0	0.1	0.2	0.5	0.4	0.3	-0.3	0.3	0.2	-0.1	-0.3	-0.2	-0.3
Intermittent access day 15 total infusions	0.4	1.1	1.9	1.1	1.0	1.0	-1.0	1.0	0.8	-1.1	-1.0	-0.8	-1.4
Intermittent access terminal intake (last 3 days)	0.7	1.2	1.9	1.2	1.1	1.0	-1.0	1.0	0.9	-1.1	-1.0	-0.9	-1.4
Intermittent access total infusions	0.3	0.3	1.0	0.7	0.6	0.5	-0.5	0.5	0.3	-0.6	-0.6	-0.4	-1.0
Intermittent access day 1 locomotion	0.0	0.0	0.0	0.2	0.1	0.0	-0.0	0.0	-0.0	0.0	0.0	0.1	-0.2
Intermittent access day 15 total locomotion	0.1	0.5	1.0	0.7	0.7	0.6	-0.6	0.6	0.5	-0.9	-0.7	-0.5	-1.0
Intermittent access total locomotion	0.5	0.6	1.2	0.8	0.8	0.7	-0.7	0.7	0.6	-1.0	-0.7	-0.6	-1.1
Intermittent access standard deviation	0.0	0.0	0.1	0.1	-0.0	-0.1	0.1	-0.1	-0.2	0.1	0.1	0.3	-0.2
Left kidney weight	0.0	0.2	0.3	0.5	0.5	0.5	-0.5	0.5	0.6	-0.1	-0.4	-0.4	-0.0
Right kidney weight	0.1	0.6	0.7	0.9	0.8	0.8	-0.8	0.8	0.8	-0.6	-0.8	-0.7	-0.5
Cocaine induced anxiety	0.1	0.2	0.4	-0.4	-0.4	-0.4	0.4	-0.4	-0.5	0.7	0.4	0.4	0.7
Post-drug Anxiety	0.2	0.3	0.3	0.4	0.4	0.5	-0.5	0.5	0.5	-0.6	-0.5	-0.6	-0.6
Baseline Anxiety	0.4	0.6	1.2	0.5	0.6	0.7	-0.7	0.7	0.8	-1.1	-0.7	-0.7	-1.1
Tail length	0.3	1.8	1.9	1.4	1.4	1.4	-1.3	1.4	1.4	-1.4	-1.4	-1.3	-1.0
Length with tail	0.5	2.3	2.8	1.7	1.6	1.6	-1.6	1.6	1.6	-1.4	-1.5	-1.5	-1.1
Length without tail	0.2	0.9	1.4	1.2	1.1	1.0	-1.0	1.0	0.9	-0.7	-0.8	-0.9	-0.7
Times rat made contact with spout	0.0	0.0	0.1	-0.2	-0.2	-0.1	0.1	-0.1	0.0	0.0	0.0	0.0	0.1
Lifetime Intake	0.4	0.5	1.0	0.9	0.7	0.6	-0.6	0.6	0.4	-0.8	-0.7	-0.4	-1.0
Liver weight, left	4.8	8.2	8.6	2.9	2.9	2.9	-2.9	2.9	2.7	-2.9	-2.9	-2.8	-2.9
Liver weight, right	3.9	6.7	7.1	2.7	2.7	2.6	-2.6	2.6	2.6	-2.5	-2.6	-2.6	-2.4
Locomotor activity	0.0	0.0	0.1	-0.1	-0.2	-0.2	0.2	-0.2	-0.3	0.3	0.2	0.2	0.2
Locomotor testing distance	0.0	0.1	0.2	-0.3	-0.3	-0.4	0.4	-0.3	-0.4	0.3	0.4	0.4	0.2
Locomotor testing rearing	0.0	0.0	0.1	-0.3	-0.2	-0.2	0.2	-0.2	-0.1	-0.1	0.2	0.2	-0.0
Locomotion in novel chamber	2.5	3.4	3.9	-1.8	-1.8	-1.9	1.9	-1.9	-1.9	1.9	2.0	2.0	1.3
Locomotion in novel chamber post-restriction	0.0	0.1	0.5	0.0	0.0	0.0	-0.0	-0.0	0.1	-0.5	0.1	0.3	-0.7
Fecal boli incidents, locomotor time 1	0.9	2.4	3.1	1.4	1.5	1.5	-1.5	1.5	1.6	-1.6	-1.6	-1.5	-1.7
Change in fecal boli incidents, locomotor task	0.3	0.3	0.4	-0.2	-0.4	-0.5	0.5	-0.5	-0.6	0.6	0.6	0.5	0.7
Time >=10cm from walls, locomotor time 1	0.0	0.0	0.1	0.2	0.2	0.1	-0.1	0.1	0.2	-0.2	-0.2	-0.2	-0.3
Bouts of movement, locomotor time 1	0.5	0.6	0.8	-0.7	-0.7	-0.7	0.7	-0.7	-0.8	0.8	0.8	0.8	0.9
Total resting periods, locomotor time 1	0.1	0.1	0.2	-0.4	-0.3	-0.3	0.3	-0.3	-0.3	0.4	0.3	0.3	0.5
Rest time, locomotor task time 1	0.2	0.3	0.6	0.4	0.5	0.5	-0.5	0.5	0.6	-0.6	-0.5	-0.6	-0.8
Distance moved, locomotor task time 1	0.2	0.6	0.8	-0.6	-0.7	-0.7	0.7	-0.7	-0.8	0.9	0.8	0.8	0.9
Vertical activity count, locomotor time 1	0.0	0.3	0.4	-0.2	-0.4	-0.5	0.5	-0.5	-0.6	0.6	0.6	0.6	0.6
Time >=10cm from walls, locomotor time 2	0.4	1.0	1.4	1.2	1.0	1.0	-1.0	1.0	1.0	-0.9	-1.0	-1.0	-1.0
Bouts of movement, locomotor time 2	0.1	0.4	0.8	-0.7	-0.6	-0.6	0.6	-0.6	-0.6	0.8	0.6	0.4	0.9
Total resting periods, locomotor time 2	0.0	0.1	0.2	-0.3	-0.3	-0.2	0.3	-0.3	-0.2	0.3	0.2	0.1	0.5
Rest time, locomotor task time 2	0.1	0.1	0.4	-0.2	0.0	0.2	-0.2	0.2	0.4	-0.6	-0.3	-0.3	-0.6
Distance moved, locomotor task time 2	0.5	0.6	1.0	-0.4	-0.6	-0.8	0.7	-0.7	-0.9	1.0	0.9	0.9	0.8
Vertical activity count, locomotor time 2	0.5	1.1	1.7	-0.4	-0.7	-1.0	0.9	-0.9	-1.2	1.3	1.2	1.2	1.2
Light reinforcement 1	0.0	0.0	0.1	-0.1	-0.1	-0.2	0.2	-0.2	-0.2	0.3	0.2	0.2	0.1
Light reinforcement 2	0.3	0.6	0.8	-0.7	-0.7	-0.8	0.8	-0.8	-0.7	0.9	0.7	0.8	0.8
Bone: marrow area	0.0	0.0	0.1	-0.0	-0.1	-0.1	0.1	-0.1	-0.2	0.2	0.1	0.1	0.4
Bone: maximum diameter	0.4	0.8	1.2	-0.7	-0.8	-0.9	0.8	-0.8	-0.9	1.0	0.9	0.9	1.1
Bone: maximum force	0.5	1.0	1.4	-0.9	-1.0	-1.0	1.0	-1.0	-1.0	1.1	1.0	1.0	1.2
Bone: maximum moment	0.7	1.3	1.6	-1.0	-1.1	-1.1	1.1	-1.1	-1.1	1.2	1.1	1.1	1.3
Mean time between licks in bursts	0.1	0.9	1.0	1.0	1.0	0.9	-0.9	0.9	1.0	-0.9	-0.9	-0.9	-0.9
Mean num. licks in bursts	0.2	0.4	0.5	0.6	0.7	0.7	-0.7	0.7	0.7	-0.6	-0.7	-0.7	-0.6
Cd content in liver	0.9	1.0	1.2	-0.9	-0.9	-1.0	1.0	-1.0	-1.0	1.0	1.0	0.9	1.1
Co content in liver	0.3	0.4	0.5	-0.6	-0.6	-0.6	0.6	-0.6	-0.6	0.6	0.7	0.7	0.5
Cu content in liver	1.4	1.7	2.1	-1.5	-1.4	-1.3	1.3	-1.3	-1.3	1.1	1.2	1.2	1.5
Fe content in liver	2.0	2.5	2.6	1.6	1.6	1.6	-1.6	1.6	1.6	-1.4	-1.6	-1.6	-1.6
K content in liver	0.1	0.1	0.1	0.4	0.3	0.3	-0.3	0.3	0.2	-0.4	-0.3	-0.3	-0.3
Mg content in liver	0.5	0.6	0.7	-0.8	-0.8	-0.8	0.8	-0.8	-0.7	0.8	0.7	0.7	0.8
Mn content in liver	0.2	0.2	0.3	-0.5	-0.5	-0.4	0.5	-0.5	-0.4	0.5	0.4	0.4	0.4
Na content in liver	0.0	0.0	0.1	0.3	0.2	0.0	-0.1	0.1	-0.1	-0.2	0.0	0.2	-0.1
Rb content in liver	0.1	0.1	0.1	0.3	0.3	0.3	-0.3	0.3	0.2	-0.1	-0.2	-0.2	-0.3
Se content in liver	0.6	0.7	0.8	-0.9	-0.8	-0.8	0.8	-0.8	-0.8	0.8	0.7	0.7	0.8
Sr content in liver	0.5	0.4	0.4	0.7	0.7	0.7	-0.7	0.7	0.7	-0.6	-0.6	-0.6	-0.7
Zn content in liver	0.3	0.4	0.4	0.6	0.6	0.7	-0.6	0.6	0.7	-0.6	-0.6	-0.7	-0.5
Bone: minimum diameter	0.1	0.2	0.3	-0.3	-0.4	-0.4	0.4	-0.4	-0.3	0.5	0.5	0.4	0.6
Time in familiar zone, hab. session 1	0.3	0.4	0.5	-0.5	-0.6	-0.6	0.6	-0.6	-0.6	0.5	0.6	0.7	0.7
Time in novel zone, hab. session 1	0.2	0.2	0.3	0.4	0.4	0.4	-0.4	0.4	0.5	-0.4	-0.5	-0.5	-0.5
Total zone transitions, hab. session 1	0.1	0.1	0.1	-0.2	-0.2	-0.3	0.3	-0.3	-0.3	0.4	0.3	0.3	0.4
Total locomotion distance, hab. session 1	0.1	0.1	0.3	-0.3	-0.3	-0.3	0.3	-0.3	-0.3	0.5	0.3	0.3	0.4
Locomotion velocity, hab. session 1	0.3	0.5	0.8	-0.7	-0.7	-0.7	0.7	-0.7	-0.7	0.9	0.7	0.6	0.7
Time in familiar zone, hab. session 2	0.1	0.1	0.2	-0.4	-0.4	-0.3	0.3	-0.3	-0.3	0.3	0.3	0.3	0.2
Time in novel zone, hab. session 2	0.2	0.2	0.3	-0.3	-0.4	-0.4	0.4	-0.4	-0.5	0.5	0.5	0.5	0.5
Total zone transitions, hab. session 2	0.2	0.3	0.3	0.6	0.6	0.6	-0.6	0.6	0.6	-0.6	-0.6	-0.5	-0.5
Total locomotion distance, hab. session 2	0.0	0.1	0.1	-0.3	-0.3	-0.2	0.2	-0.2	-0.2	0.3	0.2	0.2	0.2
Locomotion velocity, hab. session 2	0.1	0.1	0.1	-0.4	-0.3	-0.3	0.3	-0.3	-0.2	0.3	0.2	0.2	0.3
Novel to familiar place preference ratio	0.7	0.9	1.0	1.0	1.0	0.9	-0.9	0.9	0.9	-0.9	-0.9	-0.9	-0.9
Novelty place preference	0.9	1.1	1.3	1.1	1.1	1.1	-1.1	1.1	1.1	-1.0	-1.1	-1.1	-1.0
Time in novel zone, NPP test	1.0	1.2	1.3	1.2	1.1	1.1	-1.1	1.1	1.1	-1.0	-1.1	-1.1	-1.1
Total zone transitions, NPP test	0.0	0.0	0.0	0.1	0.1	0.1	-0.1	0.1	0.1	0.0	-0.1	-0.1	-0.0
Total locomotion distance, NPP test	0.8	1.2	1.4	-1.1	-1.1	-1.1	1.1	-1.1	-1.0	1.2	1.0	1.0	1.1
Locomotion velocity, NPP test	1.0	1.4	1.7	-1.2	-1.2	-1.2	1.2	-1.2	-1.2	1.3	1.2	1.1	1.2
Intraocular pressure	0.9	1.5	1.7	-1.3	-1.3	-1.3	1.3	-1.3	-1.3	1.2	1.2	1.2	1.1
Delta distance traveled before/after self-admin	2.9	3.2	3.4	1.9	1.8	1.8	-1.8	1.8	1.8	-1.6	-1.8	-1.8	-1.7
Delta ambulatory time before/after self-admin	1.5	2.5	2.9	1.7	1.6	1.6	-1.6	1.6	1.6	-1.5	-1.6	-1.5	-1.5
Parametrial fat weight	6.3	14.7	15.5	3.9	3.9	3.9	-3.9	3.9	3.9	-3.8	-3.8	-3.8	-3.6
Pavlov. Cond. lever latency	0.0	0.0	0.0	0.1	0.1	0.2	-0.2	0.2	0.2	-0.1	-0.2	-0.2	-0.0
Pavlov. Cond. magazine entry latency	0.0	0.0	0.0	0.1	0.1	0.1	-0.1	0.1	0.1	-0.1	-0.1	-0.1	-0.1
Pavlov. Cond. change in total contacts	0.3	0.3	0.4	-0.6	-0.6	-0.6	0.6	-0.6	-0.6	0.4	0.6	0.6	0.4
Pavlov. Cond. index score	0.0	0.0	0.1	-0.1	-0.2	-0.2	0.2	-0.2	-0.2	0.1	0.2	0.3	0.1
Pavlov. Cond. latency score	0.0	0.0	0.0	-0.0	-0.0	-0.1	0.1	-0.1	-0.1	0.0	0.1	0.1	-0.1
Pavlov. Cond. lever contacts	0.0	0.0	0.0	-0.0	-0.1	-0.1	0.1	-0.1	-0.2	0.1	0.2	0.2	-0.1
Pavlov. Cond. magazine entry number	0.1	0.2	0.2	0.4	0.4	0.4	-0.4	0.4	0.5	-0.4	-0.5	-0.5	-0.4
Pavlov. Cond. intertrial magazine entries	0.2	0.2	0.3	-0.5	-0.5	-0.5	0.5	-0.5	-0.4	0.5	0.4	0.4	0.5
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.1	0.2	-0.3	-0.3	-0.3	0.3	-0.3	-0.4	0.2	0.4	0.4	0.2
Pavlov. Cond. response bias	0.0	0.0	0.0	-0.1	-0.1	-0.1	0.1	-0.1	-0.2	0.1	0.2	0.2	0.1
Pavlov. Cond. lever latency	2.5	3.5	3.7	1.9	1.9	1.9	-1.9	1.9	1.9	-1.9	-1.8	-1.8	-1.8
Pavlov. Cond. magazine entry latency	0.2	0.3	0.3	-0.5	-0.5	-0.5	0.5	-0.5	-0.5	0.5	0.5	0.5	0.4
Pavlov. Cond. change in total contacts	0.9	2.1	2.4	-1.5	-1.5	-1.5	1.5	-1.5	-1.5	1.5	1.4	1.4	1.4
Pavlov. Cond. index score	1.9	3.0	3.2	-1.8	-1.8	-1.8	1.8	-1.8	-1.8	1.7	1.7	1.7	1.7
Pavlov. Cond. latency score	2.2	3.5	3.8	-1.9	-1.9	-1.9	1.9	-1.9	-1.9	1.8	1.8	1.9	1.8
Pavlov. Cond. lever contacts	1.3	1.9	2.1	-1.5	-1.4	-1.4	1.4	-1.4	-1.4	1.4	1.3	1.3	1.3
Pavlov. Cond. magazine entry number	0.0	0.0	0.0	0.2	0.2	0.2	-0.2	0.2	0.2	-0.1	-0.1	-0.2	-0.1
Pavlov. Cond. intertrial magazine entries	0.3	0.7	0.8	0.8	0.8	0.8	-0.8	0.8	0.9	-0.8	-0.8	-0.9	-0.8
Pavlov. Cond. lever-magazine prob. diff.	1.5	2.3	2.4	-1.6	-1.5	-1.5	1.5	-1.5	-1.6	1.5	1.5	1.5	1.4
Pavlov. Cond. response bias	1.2	1.6	1.8	-1.3	-1.3	-1.3	1.3	-1.3	-1.3	1.3	1.2	1.2	1.2
Time in closed arm before self-admin	0.9	1.6	2.3	1.4	1.3	1.2	-1.2	1.2	1.1	-1.5	-1.2	-1.0	-1.4
Time in closed arm after self-admin	1.0	1.1	1.6	-0.8	-1.0	-1.1	1.1	-1.1	-1.2	0.9	1.2	1.2	1.1
Time in open arm before self-admin	1.4	1.7	2.4	-1.5	-1.4	-1.2	1.3	-1.3	-1.1	1.6	1.2	1.0	1.4
Time in open arm after self-admin	1.1	1.2	1.2	1.1	1.1	1.1	-1.1	1.1	1.1	-1.1	-1.1	-1.1	-1.1
Bone: periosteal estimation	0.4	1.0	1.5	-0.8	-0.9	-0.9	0.9	-0.9	-1.0	1.1	1.0	0.9	1.2
Bone: periosteal perimeter	0.3	0.7	1.2	-0.6	-0.7	-0.8	0.8	-0.8	-0.8	0.9	0.9	0.8	1.1
Bone: post-yield work	0.2	0.3	0.4	0.6	0.6	0.5	-0.5	0.5	0.5	-0.6	-0.5	-0.4	-0.6
Progressive ratio test 1 active lever presses	0.4	0.6	1.0	-0.7	-0.8	-0.9	0.8	-0.8	-1.0	0.6	0.8	1.0	0.4
Progressive ratio test 1 breakpoint	0.4	0.7	1.1	-0.7	-0.8	-0.9	0.9	-0.9	-1.0	0.7	0.9	1.0	0.5
Progressive ratio test 1 inactive lever presses	1.0	2.6	3.2	-1.4	-1.5	-1.6	1.6	-1.6	-1.8	1.7	1.6	1.7	1.5
Progressive ratio test 2 active lever presses	0.3	0.4	0.5	-0.6	-0.6	-0.6	0.6	-0.6	-0.7	0.5	0.6	0.7	0.4
Progressive ratio test 2 breakpoint	0.2	0.3	0.4	-0.6	-0.6	-0.6	0.6	-0.6	-0.6	0.4	0.5	0.6	0.3
Progressive ratio test 2 inactive lever presses	0.0	0.1	0.2	-0.3	-0.4	-0.4	0.4	-0.4	-0.4	0.4	0.4	0.4	0.4
Incentive Sensitization - Responses	0.0	0.0	0.1	0.0	0.1	0.1	-0.1	0.1	0.2	-0.1	-0.2	-0.3	-0.1
Incentive Sensitization - Breakpoint	0.0	0.0	0.1	0.1	0.1	0.2	-0.2	0.2	0.2	-0.2	-0.3	-0.3	-0.2
Sum of active levers in priming session hrs 5-6	1.7	1.6	1.7	1.2	1.3	1.3	-1.3	1.3	1.3	-1.3	-1.3	-1.3	-1.2
Progressive ratio	0.0	0.1	0.3	0.1	0.2	0.3	-0.3	0.3	0.4	-0.2	-0.5	-0.5	-0.5
Food seeking constrained by brief footshock	0.1	0.1	0.2	0.3	0.3	0.3	-0.3	0.3	0.4	-0.4	-0.3	-0.4	-0.2
Seeking ratio, punishment vs. effort	0.1	0.2	0.4	-0.2	-0.3	-0.5	0.4	-0.5	-0.5	0.2	0.6	0.7	0.5
Retroperitoneal fat weight	0.4	1.9	2.5	1.6	1.5	1.4	-1.4	1.4	1.3	-1.4	-1.3	-1.2	-1.2
Reaction time number correct	0.4	1.3	1.4	1.2	1.2	1.1	-1.2	1.2	1.2	-1.0	-1.1	-1.2	-1.0
Reaction time mean minus median	0.1	0.3	0.5	0.5	0.6	0.6	-0.6	0.6	0.6	-0.6	-0.6	-0.6	-0.7
Reaction time mean minus median AUC	0.3	2.3	2.7	1.5	1.5	1.5	-1.5	1.5	1.5	-1.6	-1.4	-1.4	-1.6
Reaction time num false alarms	4.6	7.9	8.4	-2.9	-2.8	-2.8	2.8	-2.8	-2.9	2.9	2.7	2.7	2.7
Reaction time num false alarms AUC	3.5	8.0	8.7	-2.9	-2.9	-2.8	2.8	-2.8	-2.9	2.9	2.7	2.7	2.8
Reaction time trials correct on left	0.4	1.3	1.4	1.2	1.2	1.1	-1.2	1.2	1.2	-1.0	-1.1	-1.2	-1.0
Reaction time trials on left	0.4	1.3	1.4	1.2	1.2	1.2	-1.2	1.2	1.2	-1.0	-1.1	-1.2	-1.0
Reaction time mean	0.5	1.1	1.3	1.0	1.0	1.1	-1.1	1.1	1.1	-0.9	-1.0	-1.0	-1.0
Reaction time mean AUC	0.3	0.8	1.0	0.9	0.9	0.9	-0.9	0.9	1.0	-0.8	-0.9	-0.9	-0.8
Median of all reaction times	0.5	0.7	0.9	0.8	0.9	0.9	-0.9	0.9	1.0	-0.7	-0.9	-0.9	-0.8
Reaction time omissions	1.0	1.7	2.1	1.3	1.3	1.3	-1.3	1.3	1.2	-1.3	-1.3	-1.3	-1.5
Reaction time false alarm rate	6.0	8.3	8.7	-2.9	-2.9	-2.9	2.9	-2.9	-3.0	2.9	2.8	2.8	2.8
Reaction time premature initiation rate	0.1	0.2	0.3	0.5	0.5	0.4	-0.4	0.4	0.3	-0.4	-0.3	-0.4	-0.4
Reaction time premature initiations	0.2	0.5	0.7	0.8	0.8	0.7	-0.7	0.7	0.7	-0.7	-0.6	-0.7	-0.6
Std. dev. reaction times	0.4	1.3	1.4	1.1	1.1	1.1	-1.1	1.1	1.1	-1.1	-1.1	-1.1	-1.2
Reaction time trials completed	0.4	1.3	1.4	1.2	1.2	1.2	-1.2	1.2	1.2	-1.0	-1.1	-1.2	-1.0
Reaction time trials AUC	0.3	1.1	1.2	1.1	1.1	1.1	-1.1	1.1	1.1	-0.9	-1.0	-1.1	-0.9
Run reversals in cocaine runway, females	0.1	0.1	0.1	0.3	0.3	0.2	-0.2	0.3	0.3	0.1	-0.3	-0.4	0.2
Run reversals in cocaine runway, males	0.1	0.1	0.3	0.3	0.2	0.2	-0.2	0.2	0.2	-0.2	-0.1	0.1	-0.6
Latency to leave start box in cocaine runway	0.1	0.2	0.6	-0.8	-0.5	-0.3	0.4	-0.3	-0.1	0.5	0.1	-0.1	0.4
Latency to leave start box in cocaine runway, F	0.0	0.0	0.1	-0.3	-0.1	0.0	-0.0	0.0	0.2	0.1	-0.2	-0.3	0.1
Latency to leave start box in cocaine runway, M	0.1	0.1	0.3	-0.5	-0.4	-0.2	0.2	-0.2	-0.1	0.4	0.1	-0.1	0.2
Std. dev. time between licks in bursts	0.0	0.0	0.0	0.2	0.1	0.1	-0.1	0.1	0.1	-0.2	-0.1	0.0	0.0
Total sessions with >9 infusions	0.1	0.2	0.5	0.7	0.5	0.4	-0.4	0.4	0.2	-0.3	-0.3	-0.2	-0.4
Short access day 1 total inactive lever presses	1.9	3.8	4.9	2.2	2.0	1.9	-1.9	1.9	1.7	-2.1	-1.9	-1.8	-2.0
Short access day 10 total inactive lever presses	0.0	0.0	0.1	-0.0	-0.1	-0.2	0.2	-0.2	-0.2	-0.1	0.3	0.3	0.1
Short access day 1 total infusions	0.2	0.4	0.9	1.0	0.8	0.6	-0.6	0.6	0.5	-0.7	-0.5	-0.4	-0.7
Short access day 10 total infusions	0.1	0.2	0.5	0.7	0.5	0.4	-0.4	0.4	0.3	-0.4	-0.4	-0.2	-0.5
Short access total infusions	0.0	0.1	0.2	0.5	0.3	0.1	-0.2	0.2	-0.1	-0.4	-0.1	0.1	-0.4
Short access day 1 locomotion	0.0	0.1	0.2	-0.0	-0.1	-0.3	0.2	-0.2	-0.3	0.4	0.4	0.4	0.2
Short access day 10 total locomotion	0.2	0.7	0.9	-0.8	-0.8	-0.9	0.9	-0.9	-0.9	0.9	0.8	1.0	0.7
Short access total locomotion	0.5	0.8	1.1	-0.6	-0.8	-0.9	0.9	-0.9	-1.0	1.0	0.9	1.0	0.8
One hour access (0.3 mA shock)	0.1	0.1	0.3	-0.2	-0.3	-0.4	0.4	-0.3	-0.5	-0.2	0.2	0.4	-0.1
Compulsive drug intake	0.7	1.1	1.7	1.1	1.0	1.0	-1.0	1.0	1.0	-1.3	-1.0	-1.0	-0.9
One hour access (shock baseline)	0.1	0.2	0.4	-0.4	-0.4	-0.5	0.5	-0.5	-0.6	0.3	0.3	0.6	0.0
Social response proportion	1.9	2.4	3.0	1.7	1.6	1.6	-1.6	1.6	1.5	-1.7	-1.5	-1.4	-1.4
Social responses	1.8	2.4	2.7	1.6	1.6	1.6	-1.6	1.6	1.5	-1.5	-1.6	-1.5	-1.5
Social time	1.2	1.9	2.7	1.5	1.4	1.3	-1.3	1.3	1.3	-1.7	-1.2	-1.1	-1.5
Soleus weight	2.2	6.5	6.8	2.6	2.6	2.6	-2.6	2.6	2.6	-2.5	-2.5	-2.4	-2.5
Bone: stiffness	1.6	2.9	3.3	1.8	1.8	1.7	-1.7	1.7	1.7	-1.6	-1.6	-1.6	-1.7
Tibialis anterior weight	2.7	9.4	9.6	3.1	3.1	3.1	-3.1	3.1	3.1	-3.1	-3.0	-3.0	-2.9
Time to tail flick, vehicle, before self-admin	0.0	0.0	0.1	0.3	0.2	0.1	-0.1	0.1	0.0	-0.1	-0.1	0.0	-0.0
Time to tail flick, vehicle, after self-admin	0.3	0.6	0.8	-0.6	-0.7	-0.8	0.8	-0.8	-0.8	0.6	0.8	0.9	0.7
Time to tail flick, test, before self-admin	0.0	0.0	0.1	0.0	0.1	0.1	-0.1	0.1	0.1	-0.3	-0.2	-0.0	-0.2
Time to tail flick, test, after self-admin	0.1	0.1	0.6	-0.8	-0.5	-0.3	0.4	-0.4	-0.2	0.1	0.1	0.1	0.2
Delta time to tail flick, vehicle, before/after SA	0.2	0.2	0.4	-0.7	-0.6	-0.5	0.5	-0.5	-0.4	0.5	0.5	0.4	0.4
Delta time to tail flick, test, before/after SA	0.3	0.4	0.5	-0.7	-0.7	-0.6	0.6	-0.6	-0.6	0.6	0.6	0.5	0.6
Tibia length	0.0	0.1	0.1	-0.2	-0.3	-0.3	0.3	-0.3	-0.3	0.4	0.3	0.3	0.3
Ambulatory time before self-admin	0.8	2.6	2.9	-1.5	-1.5	-1.6	1.6	-1.6	-1.7	1.5	1.7	1.7	1.6
Ambulatory time after self-admin	0.0	0.0	0.0	0.1	0.0	-0.0	0.0	-0.0	-0.0	-0.0	0.0	-0.0	0.0
Bone: tissue strength	1.8	1.8	2.0	-1.3	-1.3	-1.4	1.3	-1.4	-1.3	1.3	1.4	1.4	1.4
Total heroin consumption	4.1	4.8	5.9	1.9	2.1	2.3	-2.2	2.2	2.4	-1.9	-2.3	-2.4	-2.1
Bone: trabecular number	2.8	5.3	5.7	2.2	2.3	2.3	-2.3	2.3	2.3	-2.4	-2.4	-2.3	-2.4
Bone: trabecular spacing	0.3	0.4	0.5	-0.6	-0.6	-0.6	0.6	-0.6	-0.7	0.6	0.7	0.7	0.6
Bone: trabecular thickness	0.0	0.0	0.0	-0.0	-0.0	-0.1	0.1	-0.1	-0.0	0.2	0.1	0.0	0.2
Bone: trabecular tissue density	1.1	1.9	2.2	-1.4	-1.4	-1.4	1.4	-1.4	-1.4	1.3	1.4	1.4	1.5
Water consumed over 24 hours	0.0	0.0	0.1	-0.1	-0.1	-0.1	0.1	-0.1	-0.1	0.2	0.1	0.1	0.3
Number of responses in last shaping day	1.1	1.4	2.1	-1.1	-1.1	-1.2	1.2	-1.2	-1.0	1.1	1.3	1.2	1.4