Hub : Genes

Nectin2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc alternative polyA NM_001012064.1 0.02 0.01 4.4e-03 0.01 0 0.01 0.01 9.3e-03 5.4e-02 3.8e-02 4.1e-02
2 Liver isoform ratio XM_006228421.4 0.02 0.02 9.5e-03 0.02 0.01 0.01 0.02 3.5e-03 9.3e-03 6.7e-02 6.5e-03
3 Liver mRNA stability Nectin2 0.59 0.18 5.0e-16 0.13 0.13 0.12 0.14 1.7e-14 4.0e-14 2.1e-13 1.0e-14
4 Brain gene expression Nectin2 0.27 0.12 0.0e+00 0.25 0.27 0.26 0.27 1.5e-23 3.4e-25 1.3e-24 3.1e-25
5 pVTA gene expression Nectin2 0.19 0.14 6.7e-08 0.06 0.05 0.05 0.04 9.5e-06 9.5e-05 1.4e-04 1.8e-04
6 NAcc gene expression Nectin2 0.24 0.12 0.0e+00 0.21 0.21 0.2 0.21 6.0e-31 1.1e-30 3.0e-30 2.1e-30
7 Eye gene expression Nectin2 0.27 0.16 3.3e-03 0.11 0.11 0.05 0.11 8.3e-03 9.7e-03 5.4e-02 1.1e-02
8 Liver alternative polyA XM_006228421.4 0.03 0.02 1.6e-03 0.01 0.02 0.01 0.02 7.3e-03 1.0e-03 1.1e-02 6.2e-03
9 Liver alternative polyA NM_001012064.1 0.03 0.02 1.8e-03 0.02 0.02 0.01 0.02 3.5e-03 1.2e-03 2.2e-02 3.2e-03
10 IL gene expression Nectin2 0.35 0.19 4.2e-05 0.15 0.12 0.11 0.16 1.9e-04 6.9e-04 1.5e-03 1.5e-04
11 PL gene expression Nectin2 0.13 0.06 0.0e+00 0.19 0.21 0.2 0.2 2.0e-20 2.8e-22 5.2e-22 8.3e-22
12 RMTg gene expression Nectin2 0.37 0.25 3.7e-04 0.08 0.11 0.07 0.07 4.8e-03 8.4e-04 8.0e-03 7.3e-03
13 LHb gene expression Nectin2 0.36 0.2 1.8e-05 0.22 0.23 0.23 0.26 7.2e-06 3.2e-06 3.3e-06 6.0e-07
14 OFC gene expression Nectin2 0.21 0.12 5.3e-04 0.11 0.11 0.07 0.1 1.4e-03 1.7e-03 1.2e-02 2.7e-03
15 Adipose gene expression Nectin2 0.35 0.17 0.0e+00 0.2 0.23 0.23 0.22 2.8e-22 8.3e-25 1.0e-24 5.2e-24
16 NAcc isoform ratio XM_006228421.4 0.02 0.01 2.3e-03 0.01 0.01 0.01 0.01 4.9e-03 2.1e-02 2.0e-02 2.7e-02
17 pVTA isoform ratio NM_001012064.1 0.05 0.04 8.7e-03 -0 -0 -0 -0 3.6e-01 5.9e-01 8.2e-01 6.4e-01
18 NAcc alternative polyA XM_006228421.4 0.02 0.01 2.6e-03 0.01 0.01 0.01 0.01 4.8e-03 2.7e-02 2.7e-02 2.4e-02
19 NAcc isoform ratio NM_001012064.1 0.02 0.01 5.6e-03 0.01 0 0 0 1.3e-02 5.3e-02 5.9e-02 5.5e-02
20 BLA gene expression Nectin2 0.28 0.17 4.9e-11 0.14 0.15 0.16 0.15 4.6e-08 1.6e-08 1.3e-08 2.2e-08
21 Liver gene expression Nectin2 0.16 0.1 4.0e-12 0.11 0.1 0.1 0.1 3.5e-12 2.8e-11 1.0e-10 6.5e-11

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.10.10.30.1-0.20.1-0.3-0.3-0.1-0.2-0.30.3-0.3-0.2-0.3-0.1-0.5-0.2-0.30.5-0.50.5-0.40.3
Area under the delay curve1.82.14.0-1.31.51.31.61.41.31.51.3-1.41.61.50.91.70.11.62.00.01.7-1.71.5-2.0
BMI with tail0.82.84.21.9-1.9-1.4-1.8-1.8-1.3-1.3-1.81.7-1.7-1.6-1.8-1.5-2.0-1.3-1.62.1-1.71.7-1.71.5
BMI without tail0.51.72.31.5-1.5-1.4-1.4-1.4-1.4-1.3-1.41.4-1.4-1.3-1.3-1.3-1.2-1.2-0.91.4-1.01.0-1.11.0
Body weight1.46.18.42.4-2.3-2.3-2.6-2.4-2.1-2.2-2.52.4-2.4-2.3-2.7-2.2-2.8-2.2-2.62.9-2.62.6-2.62.3
Weight adjusted by age0.00.00.00.1-0.2-0.10.2-0.00.00.10.1-0.00.00.00.10.00.10.0-0.1-0.1-0.20.20.00.1
Bone surface0.50.91.40.8-0.8-0.6-1.2-0.9-0.7-0.9-1.00.9-1.0-0.9-1.0-0.8-1.1-0.9-1.01.1-1.11.1-1.10.9
Bone volume0.40.61.10.6-0.6-0.5-0.7-0.7-0.6-0.8-0.80.7-0.8-0.7-0.8-0.7-1.1-0.8-0.91.0-1.01.0-1.00.9
Breakpoint value in progressive ratio session2.02.43.7-1.61.41.71.91.61.71.71.6-1.71.61.71.51.70.91.61.6-0.91.5-1.51.4-1.6
Number of licking bursts1.42.24.51.3-1.3-2.1-0.7-1.3-1.9-1.4-1.51.4-1.5-1.5-1.6-1.5-1.3-1.8-1.61.3-1.51.5-1.61.5
Context. condit. distance diff. score0.20.20.70.5-0.3-0.4-0.5-0.5-0.2-0.4-0.50.5-0.4-0.4-0.6-0.4-0.5-0.3-0.50.8-0.40.4-0.60.6
Locomotion velocity, session 10.10.10.2-0.30.20.20.30.30.30.30.2-0.20.30.30.10.4-0.30.2-0.10.2-0.40.4-0.10.1
Locomotion distance, session 10.20.20.60.3-0.2-0.2-0.4-0.2-0.5-0.4-0.40.3-0.3-0.3-0.4-0.4-0.5-0.5-0.70.5-0.70.7-0.70.7
Locomotion velocity, session 20.60.81.70.7-0.8-1.3-0.3-0.8-1.1-1.0-0.70.8-1.0-0.9-0.5-1.0-0.2-1.1-0.80.2-1.11.1-0.70.9
Locomotion distance, session 20.30.50.90.6-0.7-0.6-0.2-0.6-0.8-0.8-0.50.6-0.8-0.7-0.3-0.9-0.1-0.8-0.90.1-0.90.9-0.70.9
Locomotion velocity, session 30.10.10.30.3-0.2-0.4-0.3-0.4-0.4-0.5-0.30.4-0.5-0.4-0.1-0.50.2-0.4-0.2-0.2-0.30.3-0.20.3
Locomotion distance, session 31.11.23.6-0.91.00.91.10.91.10.81.2-1.00.90.91.50.81.90.90.8-1.80.9-0.91.1-0.8
Stereotopy head waving bouts, day 30.40.51.30.7-0.7-1.1-1.1-0.9-0.8-0.7-0.70.8-0.6-0.9-0.5-0.70.2-0.6-0.3-0.2-0.40.4-0.20.4
Stereotopy head waving duration, day 30.80.91.61.1-1.0-1.1-1.3-1.3-1.1-1.0-1.11.1-1.0-1.1-1.1-1.0-0.8-0.9-0.70.8-0.60.6-0.80.7
Locomotion velocity, session 70.10.10.3-0.00.00.50.50.10.60.10.2-0.20.10.20.40.10.20.2-0.0-0.10.4-0.40.0-0.0
Locomotion distance, session 70.20.20.60.5-0.3-0.2-0.2-0.50.1-0.3-0.40.3-0.3-0.3-0.4-0.3-0.7-0.2-0.50.8-0.60.6-0.60.4
Stereotopy head waving bouts, day 70.80.91.91.0-1.1-1.0-1.4-1.0-1.0-1.0-1.01.0-0.9-1.1-0.9-1.0-0.4-1.0-1.10.4-0.70.7-0.91.1
Stereotopy head waving duration, day 70.60.81.61.0-1.0-1.0-1.3-0.9-0.9-0.9-0.91.0-0.7-1.0-0.9-0.8-0.6-0.9-0.80.6-0.60.6-0.80.8
Locomotion velocity, session 80.20.20.8-0.30.4-0.00.50.30.20.10.4-0.30.20.20.50.10.90.20.6-0.80.6-0.60.6-0.5
Locomotion distance, session 80.10.10.40.2-0.0-0.1-0.1-0.1-0.0-0.4-0.20.2-0.4-0.2-0.2-0.4-0.2-0.3-0.50.4-0.60.6-0.50.5
Degree of sensitization distance1.31.34.81.0-0.9-0.8-1.2-1.1-0.7-0.7-1.21.1-0.8-0.8-1.6-0.8-2.2-0.7-0.92.1-1.01.0-1.20.8
Degree of sensitization stereotypy0.91.01.71.1-1.1-1.0-1.3-1.0-1.1-1.0-1.01.1-0.9-1.1-0.9-1.0-0.5-1.1-1.20.5-0.80.8-1.01.1
Conditioned locomotion0.40.53.5-0.40.30.30.50.30.20.20.6-0.40.10.21.10.11.90.20.0-1.90.4-0.40.6-0.1
Cocaine response after cond. corrected0.70.81.31.0-0.9-0.7-0.8-1.0-0.7-0.8-0.80.9-1.0-0.9-0.5-1.1-0.2-0.9-1.10.3-1.11.1-0.91.2
Cocaine response after cond. not corrected1.61.93.01.6-1.5-1.2-1.3-1.6-1.2-1.3-1.31.4-1.5-1.5-0.8-1.6-0.3-1.4-1.70.4-1.71.7-1.41.7
Cocaine response before conditioning1.21.52.01.4-1.4-1.4-1.1-1.3-1.4-1.3-1.11.3-1.3-1.4-0.8-1.3-0.1-1.3-1.30.2-1.31.3-1.11.3
Saline control response1.72.33.01.5-1.4-1.7-1.5-1.5-1.6-1.7-1.61.6-1.5-1.5-1.7-1.5-1.5-1.6-1.51.4-1.31.3-1.51.4
Bone: connectivity density0.00.00.2-0.10.10.3-0.5-0.10.0-0.0-0.20.1-0.1-0.0-0.3-0.1-0.4-0.0-0.00.4-0.10.1-0.20.0
Bone: cortical apparent density0.10.10.3-0.40.60.40.40.30.40.10.2-0.30.30.30.10.1-0.10.30.30.10.5-0.50.2-0.3
Bone: cortical area1.32.02.61.3-1.2-1.6-1.0-1.3-1.6-1.6-1.41.4-1.5-1.4-1.4-1.4-1.2-1.6-1.51.4-1.41.4-1.51.4
Bone: cortical porosity1.11.26.3-1.00.90.40.61.00.60.71.1-0.90.70.61.70.62.50.60.5-2.50.3-0.31.1-0.6
Bone: cortical porosity0.50.53.9-0.50.40.10.20.50.20.30.7-0.40.30.21.20.31.90.30.3-2.00.1-0.10.8-0.3
Bone: cortical thickness0.40.71.10.8-0.7-1.0-0.4-0.8-1.1-1.0-0.80.8-1.0-0.9-0.8-1.0-0.6-1.0-0.80.7-0.70.7-0.90.8
Bone: cortical thickness1.41.62.61.3-1.2-1.4-1.2-1.2-1.4-1.4-1.21.3-1.4-1.3-1.1-1.3-0.8-1.3-1.30.8-1.61.6-1.31.3
Bone: cortical tissue density0.10.20.4-0.40.60.50.40.40.50.20.3-0.40.40.40.20.2-0.00.40.40.00.6-0.60.3-0.4
Condit. Reinf. active minus inactive responses0.50.60.80.7-0.7-0.4-0.8-0.9-0.6-0.7-0.80.8-0.9-0.8-0.8-0.8-0.8-0.7-0.90.7-0.80.8-0.90.8
Condit. Reinf. active-inactive response ratio0.70.71.20.8-0.8-0.3-1.0-1.0-0.6-0.7-0.90.9-0.9-0.8-0.9-0.8-1.1-0.7-0.90.9-0.80.8-0.90.9
Condit. Reinf. active responses0.40.50.70.6-0.6-0.3-0.7-0.8-0.6-0.6-0.70.7-0.9-0.7-0.6-0.8-0.6-0.6-0.80.6-0.80.8-0.80.8
Condit. Reinf. inactive responses0.00.00.1-0.00.10.2-0.2-0.0-0.0-0.1-0.00.0-0.2-0.0-0.0-0.20.10.0-0.1-0.0-0.10.1-0.00.0
Incentive salience index mean0.20.30.60.4-0.4-0.3-0.4-0.5-0.4-0.5-0.50.5-0.7-0.6-0.3-0.7-0.1-0.6-0.80.1-0.60.6-0.50.7
Condit. Reinf. lever presses0.00.10.20.0-0.10.00.20.10.0-0.10.00.0-0.2-0.10.2-0.20.4-0.3-0.5-0.4-0.30.3-0.20.4
Condit. Reinf. active minus inactive responses0.10.20.40.6-0.6-0.2-0.4-0.5-0.4-0.3-0.40.4-0.4-0.5-0.3-0.4-0.0-0.4-0.60.0-0.50.5-0.40.5
Condit. Reinf. active-inactive response ratio0.70.81.61.1-1.2-0.6-0.9-1.0-0.7-0.8-0.70.9-0.9-1.0-0.4-0.90.1-0.8-1.3-0.1-1.01.0-0.91.2
Condit. Reinf. active responses0.10.10.4-0.20.20.30.30.30.20.40.4-0.30.30.30.40.30.60.30.2-0.60.4-0.40.5-0.5
Condit. Reinf. inactive responses0.91.22.2-1.01.20.91.11.10.81.11.0-1.01.01.10.91.10.71.11.2-0.71.3-1.31.3-1.5
Condit. Reinf. lever presses0.40.51.80.9-0.8-0.5-0.6-0.7-0.5-0.3-0.80.7-0.6-0.6-0.9-0.5-1.3-0.5-0.71.3-0.60.6-0.70.5
Condit. Reinf. lever reinforcers received0.10.20.6-0.20.20.30.40.30.30.50.4-0.40.30.30.50.40.80.40.3-0.80.5-0.50.6-0.5
Conditioned reinforcement - actives1.32.24.51.7-1.9-1.5-2.1-1.6-1.5-1.5-1.61.7-1.5-1.7-1.5-1.5-1.1-1.4-1.00.9-1.21.2-1.11.0
Conditioned reinforcement - inactives0.30.40.80.8-0.9-0.7-0.6-0.9-0.7-0.7-0.70.7-0.7-0.7-0.5-0.7-0.4-0.6-0.40.2-0.60.6-0.40.4
Conditioned locomotion2.43.14.51.9-2.1-1.8-2.1-1.8-1.8-1.7-1.81.9-1.7-1.9-1.6-1.7-1.2-1.7-1.71.1-1.81.8-1.61.7
Patch foraging indifference point 0 sec0.30.61.10.5-0.4-0.9-0.5-0.7-1.0-0.8-0.70.7-0.9-0.8-0.5-0.8-0.4-0.9-1.10.5-1.01.0-0.80.9
Patch foraging indifference point AUC2.13.04.51.9-1.7-2.1-1.9-1.7-2.0-1.9-1.81.9-1.8-1.9-1.7-1.9-1.3-1.9-1.51.3-1.11.1-1.51.6
Delay disc. indifference point, 0s delay1.51.62.0-0.71.21.21.11.21.21.31.3-1.31.31.31.31.31.41.31.3-1.41.3-1.31.4-1.3
Delay disc. indifference point, 16s delay1.41.53.4-1.11.41.11.51.11.11.10.9-1.11.21.20.61.3-0.31.31.80.51.4-1.41.1-1.8
Delay disc. indifference point, 2s delay3.43.75.7-1.82.11.82.02.21.92.31.8-2.02.42.21.32.40.22.32.0-0.22.1-2.11.7-2.0
Delay disc. indifference point, 24s delay0.50.63.30.8-0.8-0.3-0.3-0.6-0.3-0.4-0.70.6-0.3-0.4-0.8-0.3-1.8-0.2-0.51.8-0.80.8-0.90.5
Delay disc. indifference point, 4s delay0.00.00.10.10.1-0.0-0.2-0.1-0.10.20.0-0.00.20.0-0.10.20.00.30.40.00.2-0.20.2-0.4
Delay disc. indifference point, 8s delay2.02.34.3-1.61.61.31.71.41.31.51.3-1.41.61.51.01.60.31.62.1-0.31.8-1.81.6-2.1
Indifference point function ln k0.50.91.6-1.11.01.11.31.01.00.91.0-1.00.91.11.01.00.61.00.8-0.60.7-0.70.8-0.9
Indifference point function log k0.50.91.6-1.11.01.11.31.01.00.91.0-1.00.91.11.01.00.61.00.8-0.60.7-0.70.8-0.9
Patch foraging total patch changes 0 sec0.61.22.00.8-0.7-1.2-0.8-0.9-1.3-1.1-1.11.1-1.1-1.1-1.0-1.1-0.9-1.1-1.41.0-1.41.4-1.21.2
Patch foraging total patch changes 12 sec0.81.11.71.2-0.9-1.2-1.1-1.1-1.3-1.0-1.01.1-1.2-1.2-0.7-1.2-0.3-1.2-1.10.3-0.80.8-0.91.1
Patch foraging total patch changes 18 sec2.33.55.11.8-1.5-1.8-2.2-1.8-1.9-1.7-2.02.0-1.7-1.9-2.1-1.8-2.0-1.8-1.92.0-1.81.8-2.01.9
Patch foraging total patch changes 24 sec0.40.61.30.8-0.6-0.7-1.1-0.9-0.8-0.7-0.90.9-0.7-0.8-0.9-0.8-0.9-0.6-0.60.9-0.50.5-0.70.7
Patch foraging total patch changes 6 sec1.82.84.81.6-1.4-1.9-1.7-1.7-2.2-1.9-1.71.8-1.9-1.8-1.4-1.9-0.8-1.8-1.70.8-1.61.6-1.41.6
Patch foraging time to switch 0 sec2.55.16.7-2.42.42.41.82.42.52.42.3-2.32.62.42.02.51.82.42.3-1.82.1-2.12.2-2.3
Patch foraging water rate 0 sec2.85.87.12.6-2.7-2.6-2.2-2.6-2.6-2.6-2.52.5-2.6-2.6-2.2-2.6-1.9-2.5-2.41.9-2.12.1-2.32.4
Patch foraging water rate 12 sec0.30.50.90.7-0.8-0.5-0.5-0.8-0.6-0.7-0.80.7-0.7-0.7-0.7-0.7-0.9-0.6-0.81.0-0.80.8-0.80.7
Patch foraging water rate 18 sec0.30.51.90.4-0.6-0.6-0.5-0.6-0.5-0.6-0.70.6-0.5-0.5-0.8-0.6-1.4-0.5-0.51.2-0.70.7-0.60.4
Patch foraging water rate 24 sec0.70.91.40.9-1.1-1.0-1.0-1.1-1.0-1.0-1.11.0-1.1-1.0-1.1-1.0-1.2-0.9-0.81.0-0.70.7-0.90.8
Patch foraging water rate 6 sec1.21.84.61.2-1.3-1.1-1.0-1.2-1.1-1.2-1.41.3-1.2-1.1-1.6-1.2-2.1-1.1-1.12.1-1.01.0-1.41.1
Seeking ratio, delayed vs. immediate footshock2.12.64.2-1.41.41.61.51.61.61.41.6-1.61.41.51.61.42.11.51.9-1.71.7-1.71.8-1.7
Distance traveled before self-admin0.10.10.30.3-0.2-0.3-0.1-0.2-0.4-0.3-0.30.3-0.3-0.3-0.2-0.3-0.2-0.4-0.40.2-0.30.3-0.40.5
Distance traveled after self-admin0.40.41.0-0.50.70.40.90.50.40.40.7-0.60.40.50.80.41.00.40.7-1.00.8-0.80.7-0.5
Extensor digitorum longus weight1.97.410.02.4-2.5-2.8-2.4-2.5-2.6-2.8-2.82.7-2.7-2.5-3.0-2.4-3.2-2.7-2.93.0-2.92.9-2.92.7
Bone: elastic displacement1.01.11.7-1.01.11.20.81.21.21.11.1-1.11.01.11.31.01.21.10.8-1.20.6-0.61.1-1.0
Bone: elastic work0.10.10.30.2-0.1-0.0-0.4-0.1-0.1-0.2-0.00.1-0.1-0.20.2-0.10.5-0.1-0.4-0.6-0.50.50.00.1
Bone: endosteal estimation0.00.00.10.1-0.10.3-0.2-0.00.30.10.0-0.00.00.10.10.2-0.20.2-0.20.1-0.10.1-0.10.0
Bone: endosteal perimeter0.00.00.2-0.00.00.00.10.00.00.1-0.1-0.0-0.10.1-0.20.1-0.3-0.0-0.20.5-0.10.1-0.20.1
Epididymis fat weight0.31.11.8-1.21.30.91.31.11.01.01.1-1.11.01.11.01.00.80.91.1-0.91.0-1.01.1-1.2
Delta time in closed arm before/after self-admin0.10.10.5-0.20.30.2-0.10.20.20.2-0.0-0.10.20.2-0.30.2-0.70.30.20.70.1-0.1-0.0-0.2
Delta time in open arm before/after self-admin0.10.10.5-0.10.10.20.30.20.10.20.3-0.30.20.20.40.20.70.10.2-0.70.3-0.30.4-0.3
Diff in mean of infusions in LGA sessions1.21.41.8-1.21.21.31.01.31.31.31.2-1.21.31.31.01.30.71.31.2-0.81.2-1.21.1-1.3
Delay discount exponential model param1.41.52.91.1-1.3-1.1-1.3-1.1-1.1-1.3-1.01.1-1.4-1.2-0.7-1.40.1-1.4-1.7-0.2-1.41.4-1.21.7
Extinction: sum of active levers before priming0.20.21.1-0.30.30.30.50.30.30.30.5-0.40.20.30.70.31.00.30.2-1.10.2-0.20.5-0.3
Active lever presses in extinction session 60.30.20.80.2-0.4-0.2-0.1-0.2-0.2-0.2-0.30.3-0.2-0.2-0.3-0.2-0.6-0.3-0.90.7-0.90.9-0.80.7
Bone: final force0.40.61.00.8-0.7-0.8-0.7-0.9-0.8-0.8-0.80.8-0.8-0.8-0.7-0.6-0.6-0.7-1.00.7-0.90.9-0.90.8
Bone: final moment0.50.81.20.9-0.8-1.0-0.9-1.0-0.9-0.9-0.90.9-0.9-1.0-0.8-0.7-0.6-0.9-1.10.7-0.90.9-1.01.0
Food consumed during 24 hour testing period3.75.16.6-2.32.32.61.42.32.62.52.2-2.22.42.32.02.41.82.52.2-1.92.3-2.32.3-2.3
Glucose0.30.50.8-0.30.40.60.50.30.80.90.6-0.60.90.60.60.80.40.90.7-0.40.8-0.80.8-0.9
Heart weight1.82.83.71.8-1.8-1.9-1.4-1.7-1.8-1.8-1.71.7-1.8-1.8-1.6-1.7-1.2-1.8-1.61.4-1.71.7-1.61.7
Delay discount hyperbolic model param1.31.42.71.1-1.3-1.0-1.3-1.1-1.0-1.3-1.01.1-1.4-1.2-0.7-1.40.2-1.4-1.6-0.2-1.41.4-1.11.6
Intermittent access intake day 1-15 change0.20.51.40.5-0.7-0.5-1.0-0.5-0.4-0.4-0.70.6-0.4-0.5-1.0-0.4-1.2-0.4-0.51.1-0.60.6-0.70.5
Intermittent access intake escalation0.30.61.60.7-0.8-0.6-1.2-0.7-0.5-0.5-0.80.7-0.5-0.6-1.1-0.4-1.3-0.4-0.51.2-0.60.6-0.70.5
Intermittent access intake escalation 20.00.00.30.4-0.4-0.1-0.5-0.3-0.1-0.1-0.20.2-0.1-0.2-0.2-0.10.1-0.0-0.1-0.0-0.20.2-0.10.1
Intermitt. access day 1 inactive lever presses0.00.00.20.1-0.0-0.00.4-0.1-0.0-0.0-0.00.0-0.0-0.00.0-0.0-0.3-0.0-0.00.4-0.40.4-0.1-0.0
Intermitt. access day 15 inactive lever presses0.10.22.0-0.10.1-0.1-0.0-0.1-0.0-0.0-0.30.2-0.0-0.0-0.7-0.0-1.4-0.00.01.3-0.20.2-0.4-0.0
Intermitt. access escalation Index0.20.30.6-0.70.80.60.50.60.60.50.6-0.60.50.60.50.50.30.40.3-0.30.4-0.40.4-0.3
Intermittent access day 1 total infusions1.21.93.01.6-1.5-1.5-1.7-1.7-1.5-1.5-1.61.6-1.5-1.6-1.5-1.5-1.4-1.3-0.81.1-0.90.9-1.00.8
Intermittent access day 15 total infusions1.01.53.71.3-1.3-1.1-1.7-1.3-1.1-1.0-1.41.3-1.0-1.2-1.6-1.0-1.9-0.9-0.61.7-0.80.8-1.00.6
Intermittent access terminal intake (last 3 days)1.41.83.61.6-1.6-1.3-1.8-1.4-1.3-1.2-1.51.4-1.2-1.3-1.7-1.2-1.9-1.1-0.71.7-1.01.0-1.10.8
Intermittent access total infusions2.63.14.72.0-2.0-1.8-2.1-1.9-1.7-1.7-1.91.9-1.7-1.8-2.0-1.7-2.2-1.5-1.21.9-1.41.4-1.51.3
Intermittent access day 1 locomotion0.30.30.90.9-0.9-0.6-0.8-0.8-0.6-0.6-0.60.7-0.6-0.7-0.4-0.60.1-0.5-0.2-0.1-0.30.3-0.20.3
Intermittent access day 15 total locomotion0.20.31.60.7-0.6-0.5-1.3-0.7-0.5-0.5-0.70.7-0.5-0.6-0.7-0.4-0.6-0.4-0.00.4-0.20.2-0.10.0
Intermittent access total locomotion1.62.04.31.8-1.7-1.4-2.1-1.7-1.4-1.4-1.61.6-1.4-1.6-1.5-1.4-1.3-1.2-0.71.1-0.90.9-0.90.8
Intermittent access standard deviation0.10.10.3-0.10.10.4-0.20.30.40.50.3-0.30.50.30.20.50.10.60.4-0.10.1-0.10.3-0.4
Left kidney weight5.425.129.35.2-5.2-5.0-4.9-5.2-5.1-5.3-5.05.1-5.4-5.2-4.6-5.4-3.6-5.2-5.33.5-5.25.2-4.95.2
Right kidney weight5.123.126.05.0-5.0-4.9-4.7-4.9-4.8-4.9-4.94.9-5.1-4.9-4.5-5.0-3.7-4.9-5.13.7-4.94.9-4.84.9
Cocaine induced anxiety0.30.40.7-0.60.50.50.80.50.60.60.5-0.60.60.70.20.6-0.50.70.80.50.7-0.70.5-0.8
Post-drug Anxiety0.10.10.2-0.40.30.20.40.30.30.30.2-0.30.30.40.00.3-0.50.30.40.50.3-0.30.1-0.4
Baseline Anxiety0.00.10.4-0.10.10.0-0.20.0-0.0-0.00.1-0.0-0.0-0.10.3-0.00.6-0.1-0.2-0.7-0.10.10.10.2
Tail length0.20.91.61.0-0.9-1.2-0.9-0.9-1.3-1.2-1.01.0-0.9-1.0-1.0-0.9-0.8-1.0-0.91.0-0.70.7-1.00.9
Length with tail0.41.62.41.1-1.1-1.2-1.1-1.1-1.2-1.3-1.31.2-1.1-1.2-1.4-1.1-1.4-1.2-1.61.4-1.41.4-1.41.3
Length without tail0.92.86.11.3-1.3-1.1-1.5-1.4-1.1-1.2-1.71.5-1.4-1.3-1.9-1.2-2.5-1.3-2.12.3-2.22.2-2.01.8
Times rat made contact with spout0.10.10.20.1-0.10.2-0.2-0.20.0-0.1-0.10.1-0.2-0.20.1-0.20.2-0.1-0.5-0.3-0.50.5-0.30.4
Lifetime Intake2.32.84.31.9-1.9-1.7-2.1-1.8-1.7-1.7-1.81.8-1.7-1.8-1.9-1.6-1.9-1.5-1.11.7-1.31.3-1.41.2
Liver weight, left1.42.33.61.5-1.6-1.9-1.6-1.5-1.9-1.7-1.51.6-1.7-1.7-1.2-1.6-0.6-1.7-1.50.5-1.51.5-1.11.2
Liver weight, right1.52.63.41.6-1.7-1.4-1.7-1.6-1.6-1.7-1.71.6-1.6-1.6-1.5-1.6-1.6-1.5-1.61.5-1.81.8-1.61.6
Locomotor activity1.32.03.81.3-1.4-1.9-1.0-1.3-1.9-1.8-1.31.4-1.6-1.5-1.3-1.6-0.7-1.7-1.30.7-1.21.2-1.11.2
Locomotor testing distance0.71.22.31.0-1.2-1.5-0.8-1.0-1.5-1.4-1.11.1-1.2-1.1-1.1-1.2-0.7-1.3-1.00.8-0.80.8-0.90.9
Locomotor testing rearing3.87.68.82.9-2.8-3.0-2.8-2.8-3.0-2.8-2.92.8-2.8-2.8-2.9-2.9-2.4-2.8-2.82.4-2.52.5-2.72.6
Locomotion in novel chamber0.20.30.9-0.40.40.30.90.50.40.40.5-0.50.40.50.40.40.40.40.7-0.20.6-0.60.5-0.7
Locomotion in novel chamber post-restriction0.81.31.9-1.31.41.21.01.21.01.11.2-1.21.11.21.11.21.01.21.1-1.21.1-1.11.1-0.9
Fecal boli incidents, locomotor time 10.00.00.10.2-0.3-0.2-0.1-0.1-0.1-0.1-0.10.1-0.1-0.1-0.1-0.1-0.0-0.1-0.20.0-0.30.3-0.00.0
Change in fecal boli incidents, locomotor task0.80.81.2-1.10.80.90.70.80.80.90.8-0.81.00.90.71.00.31.01.1-0.31.0-1.00.9-1.1
Time >=10cm from walls, locomotor time 10.10.10.80.5-0.00.1-0.5-0.30.1-0.1-0.30.3-0.3-0.2-0.4-0.2-0.9-0.0-0.10.8-0.00.0-0.40.2
Bouts of movement, locomotor time 11.82.02.8-1.51.41.71.51.41.71.61.4-1.41.41.51.21.50.51.51.6-0.61.3-1.31.4-1.7
Total resting periods, locomotor time 12.52.83.9-1.81.81.91.81.61.91.81.6-1.71.71.81.41.70.51.81.9-0.61.6-1.61.7-2.0
Rest time, locomotor task time 10.10.20.4-0.60.20.50.40.40.50.40.4-0.40.30.40.30.3-0.00.40.60.00.4-0.40.5-0.7
Distance moved, locomotor task time 10.30.51.21.0-1.1-0.7-0.4-0.6-0.8-0.7-0.40.5-0.5-0.6-0.1-0.50.6-0.6-0.9-0.6-0.70.7-0.60.9
Vertical activity count, locomotor time 10.10.22.1-0.0-0.00.10.10.20.10.10.4-0.30.30.20.70.21.40.1-0.3-1.5-0.10.10.20.2
Time >=10cm from walls, locomotor time 20.10.10.50.20.20.3-0.7-0.10.30.40.2-0.10.50.10.20.40.60.50.1-0.70.4-0.40.4-0.3
Bouts of movement, locomotor time 23.04.87.1-2.32.42.62.52.52.72.52.2-2.42.52.52.02.40.92.41.9-0.91.8-1.81.8-1.9
Total resting periods, locomotor time 22.44.36.2-2.32.32.52.42.32.52.42.1-2.22.32.41.92.20.92.21.8-0.91.6-1.61.7-1.8
Rest time, locomotor task time 20.10.10.4-0.50.40.30.20.20.20.10.3-0.2-0.20.20.4-0.10.6-0.10.4-0.60.1-0.10.4-0.2
Distance moved, locomotor task time 20.70.92.71.3-1.6-1.0-0.9-0.9-1.0-0.9-0.80.9-0.6-0.9-0.6-0.70.0-0.8-1.2-0.1-1.01.0-0.91.1
Vertical activity count, locomotor time 20.10.10.5-0.1-0.10.20.20.40.30.40.4-0.40.70.30.40.60.50.5-0.1-0.5-0.10.10.1-0.1
Light reinforcement 10.10.30.70.9-0.7-0.2-0.4-0.8-0.3-0.6-0.50.6-0.4-0.5-0.5-0.5-0.4-0.3-0.70.6-0.60.6-0.60.5
Light reinforcement 20.10.10.40.4-0.3-0.3-0.1-0.2-0.2-0.4-0.30.3-0.2-0.2-0.3-0.3-0.5-0.3-0.50.6-0.60.6-0.40.3
Bone: marrow area0.00.00.10.1-0.10.3-0.2-0.10.30.0-0.00.0-0.00.00.00.2-0.20.1-0.20.1-0.10.1-0.10.1
Bone: maximum diameter2.03.74.51.8-1.7-2.1-1.5-1.8-2.0-2.0-2.01.9-2.1-1.9-1.9-2.0-1.7-2.1-2.11.9-1.91.9-2.11.9
Bone: maximum force0.20.30.40.6-0.4-0.6-0.6-0.7-0.6-0.6-0.60.6-0.5-0.6-0.6-0.4-0.6-0.5-0.60.6-0.50.5-0.60.4
Bone: maximum moment0.20.40.60.6-0.5-0.7-0.7-0.8-0.7-0.6-0.70.7-0.6-0.7-0.7-0.4-0.6-0.5-0.70.6-0.50.5-0.60.5
Mean time between licks in bursts0.10.10.5-0.30.30.3-0.00.3-0.00.40.3-0.30.40.20.40.40.70.40.4-0.70.4-0.40.4-0.3
Mean num. licks in bursts1.32.05.0-1.21.22.20.61.11.91.31.4-1.31.31.31.71.31.61.71.2-1.61.1-1.11.4-1.2
Cd content in liver0.10.10.30.3-0.40.3-0.4-0.30.2-0.1-0.30.2-0.2-0.1-0.4-0.0-0.6-0.0-0.40.6-0.40.4-0.40.3
Co content in liver1.31.52.4-1.21.11.21.01.21.31.31.3-1.21.41.11.41.31.51.21.0-1.61.1-1.11.1-1.0
Cu content in liver0.20.20.50.3-0.3-0.70.1-0.3-0.5-0.5-0.40.4-0.5-0.4-0.5-0.4-0.6-0.7-0.40.6-0.30.3-0.60.6
Fe content in liver3.94.86.91.8-1.8-2.6-1.9-1.8-2.5-2.2-2.22.1-2.0-2.1-2.6-2.0-2.4-2.4-2.12.4-2.22.2-2.32.1
K content in liver0.10.10.4-0.10.2-0.50.50.1-0.3-0.00.1-0.1-0.2-0.00.2-0.00.6-0.3-0.0-0.4-0.00.00.10.1
Mg content in liver0.20.20.50.4-0.4-0.70.1-0.4-0.7-0.4-0.20.3-0.6-0.50.1-0.40.6-0.6-0.3-0.5-0.10.1-0.20.4
Mn content in liver0.80.91.91.1-1.1-0.9-0.7-1.1-0.9-1.0-0.50.8-1.1-1.10.2-1.01.3-0.9-0.8-1.4-0.80.8-0.40.9
Na content in liver0.10.10.40.2-0.2-0.60.1-0.2-0.4-0.2-0.20.2-0.1-0.2-0.1-0.00.0-0.3-0.2-0.0-0.40.4-0.10.2
Rb content in liver0.20.20.60.4-0.4-0.3-0.3-0.4-0.4-0.5-0.50.4-0.8-0.4-0.5-0.5-0.4-0.5-0.40.5-0.40.4-0.60.6
Se content in liver2.02.34.81.5-1.5-2.2-1.1-1.5-2.1-1.8-1.51.5-1.5-1.7-1.3-1.7-0.6-1.9-1.40.6-1.41.4-1.41.5
Sr content in liver0.10.00.3-0.10.1-0.20.10.1-0.0-0.00.2-0.10.30.00.30.20.50.00.1-0.50.1-0.10.2-0.1
Zn content in liver0.80.81.31.0-1.0-1.0-0.9-0.9-0.7-0.8-0.90.9-0.8-0.9-0.9-0.7-0.6-1.0-1.20.6-1.01.0-1.01.1
Bone: minimum diameter0.20.40.60.7-0.6-0.6-0.6-0.8-0.6-0.7-0.70.7-0.5-0.6-0.7-0.4-0.7-0.5-0.80.8-0.60.6-0.70.7
Time in familiar zone, hab. session 10.30.30.70.5-0.5-0.5-0.7-0.5-0.2-0.4-0.50.5-0.4-0.5-0.6-0.3-0.5-0.4-0.60.5-0.80.8-0.60.5
Time in novel zone, hab. session 10.50.51.00.9-1.0-0.7-0.9-1.0-0.9-0.6-0.80.8-0.7-0.8-0.7-0.7-0.6-0.6-0.50.7-0.40.4-0.60.6
Total zone transitions, hab. session 10.50.61.50.7-0.7-0.4-1.0-0.6-0.7-0.7-0.80.7-0.6-0.7-0.8-0.7-0.9-0.6-0.80.8-1.21.2-0.80.8
Total locomotion distance, hab. session 10.30.40.8-0.80.90.80.20.90.40.70.6-0.70.80.70.50.80.50.70.6-0.50.2-0.20.7-0.7
Locomotion velocity, hab. session 10.91.32.1-1.31.51.30.71.41.01.21.2-1.21.41.30.91.30.81.31.1-0.80.8-0.81.1-1.2
Time in familiar zone, hab. session 20.40.41.80.4-0.3-0.6-0.9-0.4-0.6-0.4-0.70.6-0.2-0.4-1.1-0.3-1.4-0.4-0.41.2-0.40.4-0.70.5
Time in novel zone, hab. session 20.00.00.10.2-0.40.20.1-0.20.30.20.1-0.0-0.10.00.20.10.20.20.1-0.10.1-0.10.1-0.2
Total zone transitions, hab. session 20.40.61.10.7-0.7-0.8-0.7-0.7-0.8-0.7-0.60.7-0.6-0.8-0.4-0.6-0.2-0.8-1.0-0.0-1.01.0-0.81.0
Total locomotion distance, hab. session 20.50.71.0-0.90.90.80.60.90.80.90.9-0.91.00.80.91.00.90.80.5-1.00.4-0.40.7-0.5
Locomotion velocity, hab. session 20.30.41.0-0.70.80.70.50.80.60.70.7-0.70.80.60.80.70.90.60.2-1.00.1-0.10.5-0.3
Novel to familiar place preference ratio1.31.42.41.3-1.4-0.7-1.5-1.3-0.9-1.3-1.31.3-1.4-1.2-1.3-1.3-1.1-1.1-1.11.2-0.90.9-1.21.1
Novelty place preference1.21.32.21.3-1.4-0.7-1.5-1.3-0.8-1.2-1.21.2-1.3-1.2-1.2-1.2-1.0-1.0-1.01.1-0.80.8-1.11.0
Time in novel zone, NPP test1.51.63.11.5-1.6-0.8-1.8-1.5-0.9-1.2-1.41.4-1.4-1.3-1.4-1.3-1.2-1.1-1.11.3-0.90.9-1.31.1
Total zone transitions, NPP test0.10.20.70.2-0.1-0.5-0.1-0.2-0.3-0.4-0.30.3-0.3-0.3-0.4-0.4-0.5-0.5-0.60.4-0.80.8-0.50.6
Total locomotion distance, NPP test0.30.41.00.3-0.2-0.4-0.7-0.2-0.3-0.4-0.50.5-0.3-0.4-0.8-0.4-0.8-0.5-0.70.8-1.01.0-0.70.6
Locomotion velocity, NPP test0.20.30.90.10.1-0.4-0.40.0-0.3-0.4-0.40.3-0.3-0.3-0.6-0.4-0.6-0.6-0.70.6-1.01.0-0.60.6
Intraocular pressure0.20.21.10.5-0.40.1-0.6-0.40.10.1-0.40.3-0.2-0.2-0.60.2-1.00.0-0.30.9-0.50.5-0.50.4
Delta distance traveled before/after self-admin2.22.32.9-1.41.61.41.61.41.41.41.5-1.51.41.51.51.41.41.51.7-1.31.7-1.71.6-1.6
Delta ambulatory time before/after self-admin0.60.71.0-0.70.80.71.00.70.70.70.9-0.80.70.81.00.71.00.81.0-1.01.0-1.01.0-1.0
Parametrial fat weight0.00.10.30.6-0.4-0.3-0.2-0.4-0.3-0.3-0.20.3-0.5-0.3-0.0-0.50.3-0.3-0.3-0.3-0.20.2-0.20.2
Pavlov. Cond. lever latency0.40.61.2-0.70.70.70.20.60.70.80.6-0.60.90.70.30.80.10.91.1-0.21.1-1.10.8-1.0
Pavlov. Cond. magazine entry latency0.30.30.80.4-0.5-0.1-0.5-0.3-0.4-0.3-0.50.4-0.4-0.3-0.6-0.3-0.8-0.4-0.70.9-0.80.8-0.80.7
Pavlov. Cond. change in total contacts0.40.40.9-0.60.51.00.60.70.70.70.7-0.70.60.60.80.60.80.60.2-0.70.5-0.50.4-0.3
Pavlov. Cond. index score0.30.41.10.6-0.6-0.4-0.2-0.4-0.5-0.5-0.50.5-0.6-0.5-0.3-0.6-0.3-0.7-1.00.3-1.01.0-0.80.9
Pavlov. Cond. latency score0.10.10.40.2-0.2-0.10.1-0.0-0.2-0.2-0.10.1-0.3-0.20.0-0.20.1-0.4-0.6-0.0-0.60.6-0.40.5
Pavlov. Cond. lever contacts0.30.40.90.5-0.5-0.5-0.2-0.3-0.5-0.6-0.50.5-0.7-0.5-0.3-0.6-0.1-0.8-1.00.2-1.01.0-0.70.8
Pavlov. Cond. magazine entry number0.10.10.4-0.30.3-0.00.10.10.10.00.2-0.20.20.10.20.10.40.20.6-0.50.6-0.60.6-0.6
Pavlov. Cond. intertrial magazine entries0.10.10.30.4-0.3-0.3-0.4-0.6-0.3-0.3-0.30.4-0.4-0.5-0.1-0.40.3-0.3-0.2-0.40.1-0.1-0.10.2
Pavlov. Cond. lever-magazine prob. diff.0.30.41.10.6-0.7-0.4-0.2-0.5-0.6-0.6-0.50.5-0.6-0.6-0.2-0.6-0.0-0.7-1.00.1-1.01.0-0.70.9
Pavlov. Cond. response bias1.11.42.61.1-1.1-0.8-0.9-1.0-1.0-1.1-1.11.1-1.2-1.0-1.0-1.1-1.0-1.2-1.51.1-1.61.6-1.41.5
Pavlov. Cond. lever latency0.00.10.2-0.30.40.10.20.20.2-0.10.2-0.20.20.20.10.10.30.20.3-0.40.3-0.30.3-0.3
Pavlov. Cond. magazine entry latency0.91.13.21.1-1.20.0-1.8-1.1-0.2-0.2-1.11.0-0.7-0.8-1.2-0.5-1.8-0.4-0.91.8-1.11.1-1.20.9
Pavlov. Cond. change in total contacts0.10.10.40.3-0.30.5-0.1-0.20.30.5-0.0-0.00.20.1-0.10.4-0.60.4-0.10.6-0.20.2-0.10.0
Pavlov. Cond. index score0.30.41.50.6-0.70.2-0.9-0.60.00.1-0.60.5-0.2-0.3-0.7-0.1-1.2-0.0-0.51.2-0.50.5-0.60.4
Pavlov. Cond. latency score0.20.21.10.5-0.60.3-0.7-0.40.10.3-0.40.3-0.1-0.1-0.50.1-1.00.1-0.31.0-0.30.3-0.40.2
Pavlov. Cond. lever contacts0.20.20.60.6-0.7-0.3-0.4-0.4-0.3-0.2-0.50.4-0.4-0.4-0.5-0.3-0.7-0.4-0.60.8-0.50.5-0.60.5
Pavlov. Cond. magazine entry number0.40.42.8-0.40.5-0.60.90.3-0.5-0.60.4-0.2-0.1-0.00.7-0.31.7-0.40.1-1.60.4-0.40.5-0.1
Pavlov. Cond. intertrial magazine entries0.20.31.5-0.40.5-0.11.10.5-0.2-0.10.6-0.50.20.30.8-0.11.2-0.00.3-1.20.3-0.30.6-0.3
Pavlov. Cond. lever-magazine prob. diff.0.40.51.70.8-0.90.0-1.0-0.7-0.2-0.1-0.70.6-0.4-0.5-0.8-0.2-1.3-0.2-0.61.3-0.70.7-0.80.6
Pavlov. Cond. response bias0.10.20.50.5-0.60.1-0.7-0.4-0.00.1-0.40.4-0.3-0.3-0.4-0.1-0.7-0.1-0.50.7-0.50.5-0.50.4
Time in closed arm before self-admin0.91.11.31.0-1.1-1.1-1.1-0.9-1.1-1.1-1.11.1-1.0-1.1-1.1-1.1-1.1-1.1-1.01.1-1.01.0-1.10.9
Time in closed arm after self-admin0.60.71.2-0.80.90.70.60.80.80.80.5-0.70.90.90.00.8-0.90.91.10.91.0-1.00.5-1.1
Time in open arm before self-admin1.01.11.5-0.90.91.01.10.81.11.01.1-1.10.91.01.21.01.21.11.1-1.21.0-1.01.1-1.0
Time in open arm after self-admin0.70.84.8-0.40.30.50.70.40.50.40.9-0.70.40.51.30.42.20.40.4-2.20.4-0.40.9-0.4
Bone: periosteal estimation0.30.61.00.8-0.7-0.7-0.7-0.8-0.7-0.9-0.80.8-0.8-0.8-0.7-0.6-0.8-0.8-1.00.9-0.80.8-0.90.8
Bone: periosteal perimeter0.20.40.80.5-0.4-0.6-0.3-0.5-0.7-0.6-0.60.6-0.7-0.6-0.7-0.5-0.7-0.7-0.80.9-0.50.5-0.80.7
Bone: post-yield work0.60.81.5-0.91.01.00.90.90.80.90.8-0.90.91.00.51.0-0.10.91.20.01.2-1.20.8-1.0
Progressive ratio test 1 active lever presses1.72.13.31.7-1.7-1.8-1.7-1.6-1.8-1.8-1.51.6-1.8-1.7-1.3-1.7-0.6-1.7-1.00.4-1.11.1-1.01.0
Progressive ratio test 1 breakpoint1.51.82.91.6-1.5-1.7-1.6-1.5-1.7-1.7-1.41.5-1.7-1.6-1.2-1.6-0.4-1.6-0.80.2-0.90.9-0.80.9
Progressive ratio test 1 inactive lever presses1.31.93.01.3-1.2-1.4-1.4-1.5-1.4-1.3-1.51.4-1.3-1.4-1.5-1.3-1.7-1.2-1.11.6-1.31.3-1.31.1
Progressive ratio test 2 active lever presses2.02.43.71.6-1.7-1.6-1.9-1.5-1.6-1.5-1.71.6-1.5-1.6-1.8-1.5-1.9-1.5-1.01.7-1.31.3-1.31.1
Progressive ratio test 2 breakpoint2.32.74.01.6-1.8-1.7-2.0-1.6-1.7-1.6-1.81.7-1.6-1.7-1.9-1.6-2.0-1.5-1.11.8-1.41.4-1.41.2
Progressive ratio test 2 inactive lever presses0.20.31.40.3-0.4-0.4-0.6-0.6-0.4-0.3-0.60.5-0.3-0.4-0.9-0.3-1.2-0.3-0.20.9-0.30.3-0.40.2
Incentive Sensitization - Responses1.62.36.01.3-1.5-1.2-1.6-1.3-1.2-1.1-1.61.4-1.1-1.3-1.9-1.1-2.5-1.2-1.32.4-1.41.4-1.61.3
Incentive Sensitization - Breakpoint1.62.15.91.2-1.4-1.2-1.5-1.2-1.1-1.1-1.51.4-1.1-1.2-1.8-1.1-2.4-1.1-1.32.4-1.41.4-1.61.2
Sum of active levers in priming session hrs 5-60.50.51.2-0.60.60.60.80.50.50.50.7-0.70.50.60.90.61.10.60.7-1.10.7-0.70.8-0.8
Progressive ratio1.11.83.1-1.51.51.31.11.71.41.21.2-1.31.31.40.81.40.21.41.7-0.11.7-1.71.3-1.6
Food seeking constrained by brief footshock5.46.611.1-2.22.32.62.42.22.42.42.7-2.62.52.42.82.43.32.52.5-3.22.4-2.42.8-2.5
Seeking ratio, punishment vs. effort0.60.83.4-0.50.50.91.00.40.70.91.0-0.90.80.71.30.71.80.80.5-1.80.4-0.40.9-0.6
Retroperitoneal fat weight0.00.21.00.1-0.1-0.40.4-0.2-0.0-0.3-0.30.2-0.3-0.1-0.5-0.3-0.9-0.3-0.41.0-0.50.5-0.50.2
Reaction time number correct3.87.310.33.1-3.0-2.8-2.7-3.2-2.9-2.8-2.82.8-2.7-2.8-2.8-2.7-2.3-2.5-2.42.3-2.62.6-2.42.3
Reaction time mean minus median0.00.00.20.0-0.10.2-0.30.10.30.3-0.10.00.10.1-0.20.1-0.50.10.00.40.1-0.1-0.10.0
Reaction time mean minus median AUC0.20.61.70.9-0.9-0.5-0.8-0.6-0.4-0.5-0.80.7-0.7-0.6-1.0-0.6-1.3-0.6-0.81.3-0.50.5-1.00.8
Reaction time num false alarms4.76.67.72.6-2.5-2.4-2.7-2.5-2.5-2.5-2.62.6-2.5-2.5-2.6-2.5-2.5-2.5-2.72.6-2.72.7-2.82.6
Reaction time num false alarms AUC3.45.36.22.3-2.3-2.2-2.3-2.2-2.3-2.3-2.42.3-2.2-2.3-2.3-2.2-2.2-2.3-2.42.3-2.42.4-2.52.3
Reaction time trials correct on left3.87.310.33.1-3.0-2.8-2.7-3.2-2.9-2.8-2.82.8-2.7-2.8-2.8-2.7-2.3-2.5-2.42.3-2.62.6-2.42.3
Reaction time trials on left3.97.310.33.1-3.0-2.8-2.7-3.2-2.9-2.8-2.82.8-2.7-2.8-2.7-2.7-2.3-2.5-2.42.3-2.62.6-2.52.3
Reaction time mean0.50.82.0-0.60.71.40.40.81.41.20.8-0.91.00.90.80.90.51.10.7-0.50.9-0.90.6-0.6
Reaction time mean AUC0.30.51.5-0.50.61.20.40.71.20.90.7-0.70.90.80.70.80.40.90.5-0.40.7-0.70.5-0.5
Median of all reaction times0.81.12.6-0.80.81.60.70.91.61.31.1-1.11.21.11.11.10.81.30.9-0.81.0-1.00.9-0.8
Reaction time omissions0.10.10.50.7-0.7-0.0-0.0-0.60.2-0.1-0.20.2-0.4-0.30.1-0.3-0.2-0.2-0.40.1-0.30.3-0.40.5
Reaction time false alarm rate0.20.20.50.3-0.3-0.3-0.5-0.1-0.3-0.3-0.50.4-0.4-0.3-0.5-0.4-0.7-0.5-0.70.7-0.60.6-0.70.6
Reaction time premature initiation rate0.40.51.3-0.80.80.90.40.90.80.70.8-0.70.50.70.90.61.00.60.6-1.10.5-0.50.7-0.5
Reaction time premature initiations0.30.50.70.8-0.8-0.6-0.8-0.8-0.6-0.8-0.60.7-0.8-0.7-0.5-0.8-0.2-0.7-0.70.1-0.80.8-0.60.8
Std. dev. reaction times0.10.10.4-0.10.10.50.00.40.60.50.2-0.30.40.30.20.4-0.10.40.40.10.5-0.50.2-0.2
Reaction time trials completed3.97.310.33.1-3.0-2.8-2.7-3.2-2.9-2.8-2.82.8-2.7-2.8-2.7-2.7-2.3-2.5-2.42.3-2.62.6-2.52.3
Reaction time trials AUC4.78.912.53.4-3.3-3.1-2.9-3.5-3.2-3.1-3.13.1-3.0-3.1-3.0-3.0-2.5-2.8-2.72.6-2.92.9-2.72.6
Run reversals in cocaine runway, females0.40.41.6-0.70.60.41.30.70.50.50.5-0.60.50.60.40.5-0.40.50.50.50.8-0.80.3-0.5
Run reversals in cocaine runway, males0.60.61.10.7-0.7-0.7-0.8-1.0-0.5-0.7-0.60.7-0.7-0.7-0.6-0.7-0.1-0.7-1.00.1-1.11.1-0.81.0
Latency to leave start box in cocaine runway0.40.52.50.4-0.5-0.4-0.7-0.3-0.4-0.6-0.70.6-0.5-0.4-1.0-0.5-1.5-0.4-0.51.6-0.50.5-0.70.4
Latency to leave start box in cocaine runway, F0.70.81.10.8-1.0-1.0-0.9-0.7-0.9-1.1-0.90.9-1.0-0.9-1.0-1.0-0.9-1.0-0.71.1-0.60.6-0.90.7
Latency to leave start box in cocaine runway, M0.30.21.9-0.10.10.4-0.20.20.20.1-0.20.10.10.1-0.60.1-1.40.2-0.21.4-0.30.3-0.40.2
Std. dev. time between licks in bursts0.10.10.20.1-0.20.0-0.4-0.2-0.3-0.4-0.20.3-0.3-0.2-0.1-0.3-0.1-0.2-0.30.1-0.50.5-0.20.2
Total sessions with >9 infusions2.93.55.22.2-2.1-2.2-2.3-2.1-2.2-2.1-2.02.1-2.1-2.1-1.9-2.1-1.3-2.0-1.41.1-1.31.3-1.51.5
Short access day 1 total inactive lever presses0.60.81.90.8-0.7-0.8-0.8-0.7-0.7-0.7-0.90.8-0.7-0.7-1.1-0.7-1.3-0.7-0.91.4-1.01.0-1.00.8
Short access day 10 total inactive lever presses0.51.12.7-1.01.01.21.71.21.21.21.1-1.21.21.21.01.20.41.20.8-0.20.7-0.70.6-0.8
Short access day 1 total infusions1.41.82.51.6-1.6-1.6-1.6-1.5-1.6-1.6-1.41.5-1.6-1.6-1.3-1.5-0.9-1.5-0.90.6-0.90.9-1.01.0
Short access day 10 total infusions2.93.75.12.2-2.2-2.1-2.3-2.2-2.2-2.1-2.12.1-2.1-2.2-1.8-2.1-1.4-2.0-1.41.2-1.61.6-1.51.5
Short access total infusions1.62.13.11.8-1.7-1.6-1.8-1.7-1.7-1.6-1.51.6-1.6-1.6-1.4-1.6-1.0-1.4-0.90.7-1.11.1-1.01.0
Short access day 1 locomotion2.73.34.72.1-2.0-2.0-2.2-2.0-2.0-2.0-2.02.0-2.0-2.0-1.9-2.0-1.4-1.8-1.31.4-1.31.3-1.51.4
Short access day 10 total locomotion0.10.20.60.7-0.7-0.1-0.4-0.3-0.1-0.1-0.10.2-0.1-0.30.2-0.20.8-0.1-0.3-0.5-0.50.5-0.20.3
Short access total locomotion0.70.81.81.4-1.3-0.9-1.2-1.1-1.0-1.0-0.81.0-1.0-1.1-0.4-1.00.5-0.9-0.5-0.4-0.60.6-0.30.6
One hour access (0.3 mA shock)0.20.31.70.3-0.4-0.3-0.6-0.4-0.2-0.2-0.50.4-0.2-0.3-0.8-0.2-1.3-0.2-0.21.1-0.40.4-0.50.2
Compulsive drug intake0.40.41.10.4-0.5-0.6-0.5-0.7-0.6-0.6-0.60.6-0.6-0.6-0.5-0.7-0.1-0.8-1.10.1-0.90.9-0.81.0
One hour access (shock baseline)1.01.63.71.3-1.3-1.2-1.6-1.2-1.1-1.1-1.41.3-1.1-1.2-1.6-1.1-1.9-0.9-0.81.7-1.11.1-1.10.9
Social response proportion1.92.13.21.7-1.5-1.0-1.1-1.7-1.2-1.4-1.41.4-1.4-1.4-1.2-1.3-1.5-1.2-1.61.4-1.81.8-1.61.6
Social responses1.01.21.71.2-1.3-1.0-0.8-1.3-0.9-1.2-1.11.1-1.2-1.1-1.0-1.1-1.1-1.1-1.11.1-1.21.2-1.11.1
Social time2.94.04.9-2.22.12.02.22.22.12.02.0-2.12.02.11.92.11.31.91.9-1.42.2-2.21.8-1.8
Soleus weight0.31.04.30.4-0.2-0.7-0.4-0.4-0.6-0.8-0.90.7-0.8-0.5-1.4-0.6-2.1-0.8-0.92.0-1.11.1-1.10.7
Bone: stiffness0.81.42.31.0-0.8-1.3-1.1-1.1-1.2-1.1-1.21.1-1.0-1.1-1.4-0.9-1.5-1.1-1.11.5-1.31.3-1.21.0
Tibialis anterior weight3.511.813.93.2-3.2-3.4-3.0-3.1-3.2-3.6-3.53.4-3.5-3.2-3.7-3.4-3.6-3.5-3.73.5-3.63.6-3.63.4
Time to tail flick, vehicle, before self-admin2.02.13.21.8-1.7-1.7-1.4-1.8-1.7-1.8-1.31.5-1.7-1.7-0.8-1.70.1-1.6-1.3-0.1-1.21.2-1.11.5
Time to tail flick, vehicle, after self-admin0.30.43.20.2-0.2-0.2-0.3-0.2-0.1-0.1-0.50.3-0.1-0.1-0.9-0.1-1.8-0.00.01.8-0.10.1-0.50.1
Time to tail flick, test, before self-admin1.01.04.8-0.60.60.80.80.60.80.71.0-0.80.60.71.40.72.20.70.7-2.20.7-0.71.1-0.6
Time to tail flick, test, after self-admin0.30.31.0-0.40.40.40.40.30.50.40.5-0.50.50.50.40.50.50.61.0-0.40.9-0.90.7-0.9
Delta time to tail flick, vehicle, before/after SA0.10.10.8-0.30.20.3-0.00.30.30.3-0.0-0.10.30.3-0.30.3-0.90.30.20.90.1-0.1-0.0-0.1
Delta time to tail flick, test, before/after SA0.90.92.30.9-0.8-1.0-0.9-0.9-1.0-1.0-1.01.0-0.8-0.9-1.3-0.9-1.5-0.9-0.71.5-0.60.6-1.00.6
Tibia length0.30.81.80.9-0.9-0.6-0.3-0.9-0.9-0.7-0.70.7-1.0-0.8-0.4-0.9-0.3-0.9-1.30.3-1.31.3-1.01.1
Ambulatory time before self-admin0.00.00.0-0.10.10.00.20.10.00.1-0.0-0.00.10.0-0.00.0-0.1-0.1-0.10.20.0-0.0-0.20.2
Ambulatory time after self-admin0.60.71.3-0.80.90.71.10.70.70.70.8-0.80.70.80.90.70.90.70.9-0.81.0-1.00.8-0.7
Bone: tissue strength0.80.81.5-0.60.71.00.80.60.90.90.9-0.80.70.81.00.91.00.90.9-1.01.2-1.20.9-0.8
Total heroin consumption0.00.00.0-0.10.20.10.20.20.10.10.1-0.10.10.10.20.10.20.1-0.0-0.2-0.10.10.00.0
Bone: trabecular number0.00.00.1-0.20.20.30.10.00.10.00.1-0.1-0.00.10.10.0-0.20.1-0.00.1-0.30.3-0.0-0.1
Bone: trabecular spacing0.00.00.10.1-0.1-0.3-0.2-0.0-0.1-0.0-0.10.1-0.2-0.2-0.10.00.1-0.1-0.0-0.10.3-0.3-0.10.2
Bone: trabecular thickness1.61.92.51.4-1.4-1.3-1.1-1.5-1.4-1.5-1.41.4-1.4-1.4-1.3-1.5-1.2-1.4-1.41.2-1.61.6-1.51.5
Bone: trabecular tissue density0.40.60.90.8-0.7-0.7-1.0-0.6-0.7-0.7-0.80.8-0.7-0.7-0.8-0.8-0.8-0.7-1.00.9-0.70.7-0.91.0
Water consumed over 24 hours0.10.21.20.1-0.10.60.1-0.20.30.10.3-0.20.10.10.70.11.00.3-0.4-1.1-0.40.40.10.2
Number of responses in last shaping day2.83.15.01.7-1.8-1.9-2.2-1.8-1.9-1.8-1.91.9-1.8-1.9-2.0-1.8-1.8-1.7-1.31.8-1.41.4-1.61.4