Hub : Genes

Ndufc2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Ndufc2 0.02 0.01 8.5e-03 0 0.01 -0 0 1.0e-01 3.3e-02 4.1e-01 1.7e-01
2 RMTg mRNA stability Ndufc2 0.24 0.11 1.0e-05 0.25 0.19 0.19 0.22 2.5e-07 1.1e-05 9.5e-06 1.5e-06
3 Brain gene expression Ndufc2 0.08 0.04 2.5e-07 0.06 0.08 0.07 0.07 2.5e-06 6.9e-08 1.6e-07 1.7e-07
4 Brain mRNA stability Ndufc2 0.19 0.14 2.1e-12 0.13 0.1 0.1 0.11 3.7e-12 6.3e-10 1.5e-09 2.3e-10
5 Liver gene expression Ndufc2 0.04 0.03 9.6e-04 0.02 0.02 0.01 0.01 3.3e-03 6.5e-03 9.2e-03 6.7e-03
6 PL mRNA stability Ndufc2 0.07 0.05 3.0e-05 0.02 0.03 0.03 0.03 1.6e-03 1.2e-04 5.6e-04 1.9e-04
7 Adipose gene expression Ndufc2 0.46 0.14 1.4e-15 0.07 0.1 0.12 0.08 2.4e-08 1.9e-11 1.0e-12 3.8e-09
8 PL intron excision ratio chr1_161123430_161128490 0.07 0.05 1.4e-03 0.03 0.02 0.03 0.03 1.7e-04 1.7e-03 2.4e-04 8.5e-04
9 PL intron excision ratio chr1_161128633_161129238 0.07 0.04 1.3e-03 0.03 0.02 0.03 0.03 1.8e-04 2.4e-03 3.8e-04 7.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.10.10.20.00.20.20.2-0.20.3-0.50.4-0.4
Area under the delay curve0.70.91.7-1.31.2-1.11.2-1.20.7-0.70.1-0.1
BMI with tail2.48.211.52.2-3.41.6-3.23.2-3.41.8-3.23.2
BMI without tail3.510.715.72.2-3.51.6-3.53.5-4.02.6-3.83.8
Body weight3.515.422.62.8-4.52.3-4.24.2-4.82.6-4.54.5
Weight adjusted by age0.20.20.50.4-0.7-0.3-0.70.7-0.3-0.5-0.20.2
Bone surface0.81.42.9-1.41.1-1.71.2-1.21.0-1.50.5-0.5
Bone volume0.30.51.3-0.90.6-1.10.8-0.80.4-0.7-0.10.1
Breakpoint value in progressive ratio session0.20.20.40.20.20.50.4-0.40.4-0.70.6-0.6
Number of licking bursts1.42.24.11.8-1.92.0-1.71.7-1.40.8-0.70.7
Context. condit. distance diff. score3.54.25.6-2.12.2-2.42.1-2.12.2-2.11.5-1.5
Locomotion velocity, session 11.41.52.3-1.01.5-0.91.4-1.41.5-0.21.2-1.2
Locomotion distance, session 10.50.61.1-0.80.9-0.80.8-0.81.0-0.10.8-0.8
Locomotion velocity, session 20.40.51.0-0.80.8-1.00.8-0.80.60.10.1-0.1
Locomotion distance, session 20.20.31.5-0.1-0.00.1-0.10.1-0.51.2-0.70.7
Locomotion velocity, session 30.30.30.5-0.70.7-0.60.5-0.50.6-0.20.3-0.3
Locomotion distance, session 32.62.83.7-1.71.9-1.71.8-1.81.9-1.41.3-1.3
Stereotopy head waving bouts, day 32.42.96.52.5-2.02.3-1.91.9-1.30.8-0.30.3
Stereotopy head waving duration, day 30.30.30.80.3-0.30.7-0.20.2-0.70.9-0.60.6
Locomotion velocity, session 70.40.40.6-0.70.7-0.70.6-0.60.8-0.80.5-0.5
Locomotion distance, session 70.50.61.6-1.00.6-1.20.6-0.60.8-1.30.2-0.2
Stereotopy head waving bouts, day 70.70.81.2-0.30.9-0.41.0-1.01.1-0.71.1-1.1
Stereotopy head waving duration, day 70.20.30.5-0.60.7-0.60.7-0.70.5-0.20.3-0.3
Locomotion velocity, session 86.17.312.2-3.53.5-3.23.1-3.12.5-1.61.2-1.2
Locomotion distance, session 81.42.03.1-1.71.7-1.81.6-1.61.4-0.90.7-0.7
Degree of sensitization distance1.51.52.30.9-1.50.5-1.51.5-1.40.7-1.31.3
Degree of sensitization stereotypy2.83.04.0-1.41.8-1.61.9-1.92.0-1.61.7-1.7
Conditioned locomotion0.20.20.7-0.40.40.20.5-0.5-0.10.8-0.30.3
Cocaine response after cond. corrected0.10.10.5-0.1-0.3-0.40.3-0.30.3-0.70.2-0.2
Cocaine response after cond. not corrected0.50.61.8-0.10.1-0.50.5-0.50.9-1.40.9-0.9
Cocaine response before conditioning0.70.82.50.40.30.40.1-0.11.0-0.91.6-1.6
Saline control response0.81.13.2-0.7-0.2-0.3-0.30.3-1.11.2-1.81.8
Bone: connectivity density1.11.72.7-0.61.2-0.71.2-1.21.6-1.51.7-1.7
Bone: cortical apparent density0.20.31.20.3-0.30.7-0.30.3-0.61.1-0.50.5
Bone: cortical area0.20.30.5-0.2-0.4-0.6-0.60.6-0.4-0.6-0.70.7
Bone: cortical porosity0.20.30.70.20.10.20.2-0.20.6-0.60.8-0.8
Bone: cortical porosity0.30.30.90.40.10.20.2-0.20.7-0.51.0-1.0
Bone: cortical thickness0.10.20.60.5-0.70.4-0.80.8-0.3-0.4-0.00.0
Bone: cortical thickness0.40.51.2-0.50.4-1.10.3-0.30.9-1.10.7-0.7
Bone: cortical tissue density0.20.31.10.3-0.20.7-0.20.2-0.51.0-0.40.4
Condit. Reinf. active minus inactive responses1.21.32.40.3-1.10.2-1.21.2-1.31.0-1.61.6
Condit. Reinf. active-inactive response ratio1.31.42.50.4-1.20.3-1.21.2-1.40.9-1.61.6
Condit. Reinf. active responses0.91.21.60.6-1.00.5-1.31.3-1.21.2-1.21.2
Condit. Reinf. inactive responses0.00.00.30.20.00.1-0.20.2-0.10.50.0-0.0
Incentive salience index mean0.40.41.0-0.0-0.5-0.4-0.70.7-0.70.5-1.01.0
Condit. Reinf. lever presses0.30.41.1-0.80.9-1.00.5-0.50.6-0.20.2-0.2
Condit. Reinf. active minus inactive responses1.21.55.0-1.90.7-2.20.4-0.4-0.2-0.0-1.41.4
Condit. Reinf. active-inactive response ratio0.80.92.8-1.50.8-1.70.7-0.70.2-0.1-0.70.7
Condit. Reinf. active responses1.52.15.7-2.00.4-2.40.3-0.3-0.60.2-2.12.1
Condit. Reinf. inactive responses0.81.13.0-0.3-0.5-0.6-0.60.6-1.20.9-1.71.7
Condit. Reinf. lever presses4.56.317.4-4.22.5-3.92.4-2.40.6-0.4-1.61.6
Condit. Reinf. lever reinforcers received1.62.27.0-2.20.7-2.70.5-0.5-0.3-0.0-1.91.9
Conditioned reinforcement - actives1.62.67.2-1.01.4-1.41.3-1.31.8-2.71.6-1.6
Conditioned reinforcement - inactives0.50.71.80.20.50.40.6-0.60.8-1.31.2-1.2
Conditioned locomotion4.86.211.9-1.42.3-1.82.3-2.32.9-3.42.8-2.8
Patch foraging indifference point 0 sec0.50.92.3-1.50.7-1.30.7-0.7-0.10.3-1.11.1
Patch foraging indifference point AUC0.10.10.3-0.30.0-0.60.1-0.1-0.10.1-0.30.3
Delay disc. indifference point, 0s delay0.30.41.0-0.20.3-1.00.3-0.30.7-0.90.6-0.6
Delay disc. indifference point, 16s delay0.80.82.1-1.51.2-0.71.2-1.20.30.2-0.50.5
Delay disc. indifference point, 2s delay0.80.92.8-0.80.9-1.00.9-0.90.9-1.70.6-0.6
Delay disc. indifference point, 24s delay0.20.20.6-0.60.30.10.3-0.3-0.40.3-0.80.8
Delay disc. indifference point, 4s delay0.80.82.4-1.20.8-1.50.8-0.80.4-1.2-0.30.3
Delay disc. indifference point, 8s delay0.80.91.9-1.41.2-1.11.2-1.20.7-0.2-0.10.1
Indifference point function ln k0.20.41.0-1.01.0-0.40.8-0.80.5-0.00.1-0.1
Indifference point function log k0.20.41.0-1.01.0-0.40.8-0.80.5-0.00.1-0.1
Patch foraging total patch changes 0 sec0.50.92.5-1.60.8-1.40.8-0.8-0.00.2-1.01.0
Patch foraging total patch changes 12 sec0.10.10.50.0-0.2-0.7-0.30.30.0-0.5-0.10.1
Patch foraging total patch changes 18 sec0.40.61.8-0.90.4-1.30.2-0.2-0.20.4-1.01.0
Patch foraging total patch changes 24 sec0.10.10.5-0.0-0.1-0.7-0.00.0-0.10.4-0.30.3
Patch foraging total patch changes 6 sec0.10.20.6-0.70.1-0.20.3-0.3-0.30.1-0.80.8
Patch foraging time to switch 0 sec0.91.95.32.3-1.52.2-1.21.2-0.30.01.0-1.0
Patch foraging water rate 0 sec0.81.64.1-2.01.5-2.01.3-1.30.8-0.6-0.20.2
Patch foraging water rate 12 sec0.71.43.7-1.91.4-1.41.4-1.40.30.4-0.70.7
Patch foraging water rate 18 sec0.60.91.7-1.30.4-1.00.8-0.8-0.40.8-1.31.3
Patch foraging water rate 24 sec1.31.83.9-1.91.7-1.32.0-2.00.8-0.2-0.10.1
Patch foraging water rate 6 sec0.60.91.8-1.31.3-0.91.2-1.20.70.10.1-0.1
Seeking ratio, delayed vs. immediate footshock0.40.51.40.7-0.30.20.1-0.10.6-1.21.0-1.0
Distance traveled before self-admin0.10.20.30.4-0.50.6-0.40.4-0.50.4-0.30.3
Distance traveled after self-admin0.60.82.31.2-0.61.5-0.50.50.00.80.9-0.9
Extensor digitorum longus weight0.51.95.2-0.1-1.10.1-0.90.9-1.81.0-2.32.3
Bone: elastic displacement0.00.10.10.00.00.40.2-0.20.2-0.30.3-0.3
Bone: elastic work0.30.40.7-0.40.60.20.7-0.70.7-0.50.8-0.8
Bone: endosteal estimation0.20.51.8-0.70.2-1.3-0.00.0-0.40.2-1.01.0
Bone: endosteal perimeter0.61.34.2-1.71.0-2.01.0-1.0-0.00.0-1.01.0
Epididymis fat weight1.03.46.72.2-2.61.8-2.22.2-1.9-0.2-1.11.1
Delta time in closed arm before/after self-admin2.12.05.3-1.0-0.1-0.3-0.00.0-1.42.0-2.32.3
Delta time in open arm before/after self-admin0.70.72.4-0.80.6-1.30.7-0.70.5-1.6-0.10.1
Diff in mean of infusions in LGA sessions1.31.55.21.6-1.22.3-1.31.3-1.00.5-0.10.1
Delay discount exponential model param0.80.81.71.3-1.21.0-1.11.1-0.70.6-0.00.0
Extinction: sum of active levers before priming0.40.51.7-0.4-0.2-0.3-0.00.0-0.80.1-1.31.3
Active lever presses in extinction session 61.01.01.6-0.30.8-0.01.2-1.21.1-0.91.3-1.3
Bone: final force0.30.62.1-0.70.5-0.60.5-0.50.8-1.40.6-0.6
Bone: final moment0.30.51.9-0.60.4-0.60.4-0.40.7-1.40.5-0.5
Food consumed during 24 hour testing period1.31.83.8-1.32.0-1.31.6-1.61.4-0.71.0-1.0
Glucose0.20.31.4-0.60.3-0.80.1-0.10.1-1.2-0.20.2
Heart weight0.30.51.3-0.90.2-0.50.4-0.4-0.50.6-1.11.1
Delay discount hyperbolic model param0.80.91.61.3-1.11.1-1.11.1-0.70.9-0.00.0
Intermittent access intake day 1-15 change0.81.62.6-1.41.4-1.21.6-1.61.2-1.00.7-0.7
Intermittent access intake escalation1.12.33.6-1.61.7-1.41.9-1.91.5-1.41.0-1.0
Intermittent access intake escalation 21.21.33.2-0.50.9-0.91.0-1.01.3-1.81.3-1.3
Intermitt. access day 1 inactive lever presses0.20.92.61.2-0.31.0-0.20.20.7-0.21.6-1.6
Intermitt. access day 15 inactive lever presses0.30.62.21.1-0.81.5-0.60.6-0.30.80.5-0.5
Intermitt. access escalation Index0.20.30.6-0.20.60.10.5-0.50.6-0.30.8-0.8
Intermittent access day 1 total infusions0.71.22.7-1.31.2-1.21.2-1.20.8-1.70.3-0.3
Intermittent access day 15 total infusions3.24.79.3-2.02.3-2.02.4-2.42.1-3.01.4-1.4
Intermittent access terminal intake (last 3 days)2.33.08.7-1.21.6-1.51.6-1.61.7-3.01.4-1.4
Intermittent access total infusions2.12.49.6-1.01.2-1.41.3-1.31.4-3.11.1-1.1
Intermittent access day 1 locomotion1.21.64.6-0.71.3-0.61.1-1.11.3-2.11.3-1.3
Intermittent access day 15 total locomotion0.91.63.6-0.81.2-0.81.2-1.21.4-1.91.3-1.3
Intermittent access total locomotion1.31.67.6-0.50.8-0.70.8-0.81.0-2.81.1-1.1
Intermittent access standard deviation0.20.40.60.4-0.80.0-0.50.5-0.7-0.6-0.70.7
Left kidney weight1.35.98.31.8-2.61.3-2.62.6-2.92.4-2.72.7
Right kidney weight1.25.77.61.8-2.61.1-2.62.6-2.82.2-2.62.6
Cocaine induced anxiety1.11.62.91.4-1.11.6-1.61.6-1.01.7-0.30.3
Post-drug Anxiety1.31.46.20.3-0.60.9-0.80.8-1.12.5-1.21.2
Baseline Anxiety1.01.12.7-1.61.0-1.21.3-1.30.10.4-0.90.9
Tail length1.86.912.41.2-2.40.7-2.52.5-3.32.4-3.53.5
Length with tail2.08.613.02.0-3.31.6-3.13.1-3.61.8-3.43.4
Length without tail0.82.74.41.8-2.12.0-1.91.9-1.70.6-1.11.1
Times rat made contact with spout0.81.01.51.2-1.11.1-1.01.0-1.10.7-0.70.7
Lifetime Intake2.42.98.6-1.21.5-1.61.5-1.51.7-2.91.3-1.3
Liver weight, left0.71.22.61.5-1.60.6-1.41.4-0.8-1.1-0.30.3
Liver weight, right3.45.910.33.0-3.22.0-3.23.2-2.40.6-1.41.4
Locomotor activity1.42.28.40.4-0.80.8-0.90.9-1.52.9-1.71.7
Locomotor testing distance1.62.88.30.1-0.9-0.1-1.11.1-1.72.9-2.32.3
Locomotor testing rearing2.04.15.91.2-2.00.8-2.02.0-2.32.4-2.42.4
Locomotion in novel chamber2.63.35.2-1.12.1-1.21.4-1.42.2-2.32.1-2.1
Locomotion in novel chamber post-restriction2.54.17.5-2.52.7-2.12.3-2.32.0-1.71.1-1.1
Fecal boli incidents, locomotor time 12.43.55.6-1.52.1-2.02.0-2.02.4-0.41.9-1.9
Change in fecal boli incidents, locomotor task1.51.42.70.9-1.11.5-1.11.1-1.31.6-1.01.0
Time >=10cm from walls, locomotor time 11.81.92.9-1.51.7-1.31.6-1.61.4-1.30.9-0.9
Bouts of movement, locomotor time 10.80.92.0-1.30.7-0.70.8-0.8-0.21.4-1.01.0
Total resting periods, locomotor time 10.70.81.7-1.31.0-0.61.0-1.00.11.2-0.60.6
Rest time, locomotor task time 10.70.91.8-1.41.3-0.71.3-1.30.60.50.0-0.0
Distance moved, locomotor task time 10.30.50.90.5-0.8-0.1-0.90.9-0.7-0.2-0.70.7
Vertical activity count, locomotor time 10.10.30.60.2-0.5-0.2-0.60.6-0.6-0.4-0.80.8
Time >=10cm from walls, locomotor time 20.30.51.4-0.80.6-1.20.5-0.50.5-1.0-0.10.1
Bouts of movement, locomotor time 20.10.10.2-0.1-0.1-0.2-0.20.2-0.30.2-0.50.5
Total resting periods, locomotor time 20.00.00.1-0.10.0-0.2-0.10.1-0.10.2-0.20.2
Rest time, locomotor task time 20.40.51.11.0-0.41.1-0.50.50.10.30.9-0.9
Distance moved, locomotor task time 20.60.73.0-0.70.3-1.50.3-0.30.3-1.7-0.10.1
Vertical activity count, locomotor time 20.20.30.9-0.3-0.2-1.0-0.10.1-0.2-0.8-0.70.7
Light reinforcement 10.81.93.21.7-1.81.6-1.81.8-1.20.6-0.50.5
Light reinforcement 20.10.20.40.6-0.30.4-0.40.40.2-0.40.7-0.7
Bone: marrow area0.20.41.4-0.60.1-1.2-0.10.1-0.40.2-1.01.0
Bone: maximum diameter0.40.72.0-1.20.3-1.40.2-0.2-0.3-0.6-1.01.0
Bone: maximum force0.61.12.5-1.11.0-0.90.9-0.91.1-1.60.8-0.8
Bone: maximum moment0.50.92.2-1.11.0-0.90.8-0.81.0-1.50.7-0.7
Mean time between licks in bursts0.10.31.3-0.1-0.2-1.1-0.30.3-0.3-0.4-0.70.7
Mean num. licks in bursts1.01.53.1-1.51.5-1.81.4-1.41.1-0.80.4-0.4
Cd content in liver1.11.22.70.1-1.00.3-0.90.9-1.40.9-1.71.7
Co content in liver0.20.20.9-0.40.1-1.0-0.20.2-0.00.4-0.50.5
Cu content in liver2.42.84.90.6-1.40.3-1.51.5-2.02.1-2.22.2
Fe content in liver0.20.31.10.1-0.0-0.20.1-0.10.6-1.10.7-0.7
K content in liver0.40.41.11.1-0.50.9-0.70.7-0.30.40.2-0.2
Mg content in liver0.00.00.10.20.10.2-0.10.10.00.30.1-0.1
Mn content in liver0.80.92.60.50.30.60.3-0.31.0-0.91.6-1.6
Na content in liver0.91.02.60.60.10.20.2-0.21.1-1.61.6-1.6
Rb content in liver0.40.51.2-0.1-0.30.2-0.30.3-0.91.0-1.11.1
Se content in liver1.21.43.61.9-1.01.9-0.80.80.1-0.71.2-1.2
Sr content in liver0.70.60.9-0.80.7-0.80.9-0.90.8-1.00.6-0.6
Zn content in liver0.91.02.6-0.4-0.4-0.8-0.60.6-1.01.1-1.61.6
Bone: minimum diameter0.51.01.90.1-0.8-0.5-1.11.1-1.10.8-1.41.4
Time in familiar zone, hab. session 10.10.10.3-0.10.2-0.20.2-0.20.3-0.50.2-0.2
Time in novel zone, hab. session 11.11.11.90.4-0.90.6-1.01.0-1.21.4-1.21.2
Total zone transitions, hab. session 10.10.10.6-0.20.30.70.2-0.2-0.20.8-0.10.1
Total locomotion distance, hab. session 15.67.913.83.7-3.63.1-3.53.5-2.41.4-1.11.1
Locomotion velocity, hab. session 14.66.512.73.6-3.32.9-3.23.2-2.11.0-0.70.7
Time in familiar zone, hab. session 20.30.40.6-0.70.5-0.70.5-0.5-0.30.4-0.80.8
Time in novel zone, hab. session 20.20.20.6-0.00.0-0.30.1-0.10.6-0.80.7-0.7
Total zone transitions, hab. session 20.20.20.5-0.70.30.20.4-0.4-0.20.7-0.50.5
Total locomotion distance, hab. session 24.35.68.62.7-2.92.3-2.82.8-2.31.7-1.61.6
Locomotion velocity, hab. session 24.96.59.72.7-3.12.4-3.03.0-2.62.0-1.91.9
Novel to familiar place preference ratio0.10.10.20.2-0.40.3-0.30.3-0.2-0.4-0.10.1
Novelty place preference0.00.00.1-0.0-0.30.1-0.10.1-0.2-0.3-0.20.2
Time in novel zone, NPP test0.00.00.1-0.4-0.0-0.20.1-0.1-0.1-0.3-0.30.3
Total zone transitions, NPP test0.50.71.3-1.11.1-0.61.1-1.10.70.10.3-0.3
Total locomotion distance, NPP test2.33.16.82.6-2.51.7-2.32.3-1.20.4-0.20.2
Locomotion velocity, NPP test2.94.19.13.0-2.82.1-2.62.6-1.30.4-0.20.2
Intraocular pressure4.16.09.0-3.02.9-2.73.0-3.02.3-1.91.1-1.1
Delta distance traveled before/after self-admin0.20.20.50.40.00.7-0.10.10.20.70.7-0.7
Delta ambulatory time before/after self-admin0.10.20.50.00.30.50.3-0.30.30.70.5-0.5
Parametrial fat weight1.12.63.81.5-1.91.8-1.91.9-1.71.1-1.21.2
Pavlov. Cond. lever latency0.60.71.90.9-1.01.4-0.70.7-0.80.7-0.40.4
Pavlov. Cond. magazine entry latency0.30.41.7-1.10.5-1.30.3-0.30.0-0.1-0.60.6
Pavlov. Cond. change in total contacts1.11.23.1-0.70.8-1.40.7-0.71.2-1.81.0-1.0
Pavlov. Cond. index score0.40.52.2-1.00.7-1.50.4-0.40.3-0.1-0.30.3
Pavlov. Cond. latency score0.30.42.0-0.90.6-1.40.4-0.40.4-0.5-0.10.1
Pavlov. Cond. lever contacts0.20.31.2-0.70.7-1.10.4-0.40.4-0.20.1-0.1
Pavlov. Cond. magazine entry number0.40.52.01.1-0.51.4-0.30.30.0-0.10.7-0.7
Pavlov. Cond. intertrial magazine entries0.50.61.61.3-0.71.1-0.90.9-0.30.50.3-0.3
Pavlov. Cond. lever-magazine prob. diff.0.40.52.1-1.00.8-1.40.5-0.50.4-0.2-0.10.1
Pavlov. Cond. response bias0.20.21.0-0.70.5-1.00.2-0.20.20.3-0.30.3
Pavlov. Cond. lever latency6.28.422.84.8-3.14.4-3.13.1-1.20.41.3-1.3
Pavlov. Cond. magazine entry latency4.14.912.1-3.52.6-2.92.6-2.61.5-0.6-0.10.1
Pavlov. Cond. change in total contacts3.04.813.6-3.72.2-3.42.2-2.20.6-0.2-1.31.3
Pavlov. Cond. index score5.67.520.1-4.53.0-4.13.0-3.01.3-0.7-0.90.9
Pavlov. Cond. latency score5.57.319.3-4.43.0-3.93.0-3.01.4-0.5-0.70.7
Pavlov. Cond. lever contacts5.67.721.7-4.72.8-4.22.8-2.80.80.0-1.71.7
Pavlov. Cond. magazine entry number7.49.221.04.6-3.54.3-3.53.5-2.11.3-0.00.0
Pavlov. Cond. intertrial magazine entries2.43.66.12.1-2.21.4-2.52.5-1.81.5-1.31.3
Pavlov. Cond. lever-magazine prob. diff.5.37.018.8-4.32.9-4.02.9-2.91.2-0.7-0.90.9
Pavlov. Cond. response bias6.79.124.4-4.93.3-4.63.2-3.21.4-0.5-1.11.1
Time in closed arm before self-admin0.30.40.5-0.50.7-0.20.7-0.70.7-0.50.6-0.6
Time in closed arm after self-admin1.01.12.1-1.11.5-0.41.3-1.31.1-0.10.8-0.8
Time in open arm before self-admin1.01.12.61.3-1.21.1-1.21.2-0.61.60.0-0.0
Time in open arm after self-admin0.60.61.20.8-1.10.3-1.01.0-0.80.0-0.60.6
Bone: periosteal estimation0.30.52.5-0.90.2-1.6-0.00.0-0.1-0.6-0.80.8
Bone: periosteal perimeter0.71.23.4-1.10.1-1.0-0.00.0-1.00.9-1.81.8
Bone: post-yield work0.00.00.1-0.10.20.10.2-0.20.1-0.20.3-0.3
Progressive ratio test 1 active lever presses0.70.92.1-0.51.0-0.30.9-0.91.0-1.51.0-1.0
Progressive ratio test 1 breakpoint0.80.92.0-0.61.1-0.30.9-0.91.0-1.41.0-1.0
Progressive ratio test 1 inactive lever presses0.20.31.00.40.20.70.2-0.20.60.01.0-1.0
Progressive ratio test 2 active lever presses1.61.87.9-0.91.0-1.51.1-1.11.1-2.80.7-0.7
Progressive ratio test 2 breakpoint1.82.08.4-1.01.0-1.51.2-1.21.2-2.90.8-0.8
Progressive ratio test 2 inactive lever presses0.20.31.6-0.40.4-0.50.5-0.50.5-1.20.4-0.4
Incentive Sensitization - Responses0.70.94.1-0.80.4-1.40.8-0.80.5-2.0-0.10.1
Incentive Sensitization - Breakpoint0.70.94.6-0.70.4-1.30.8-0.80.5-2.10.1-0.1
Sum of active levers in priming session hrs 5-60.40.40.70.9-0.90.8-0.60.6-0.6-0.1-0.20.2
Progressive ratio1.42.23.6-1.81.8-1.61.9-1.91.4-0.10.6-0.6
Food seeking constrained by brief footshock1.11.44.2-0.3-0.5-0.4-0.50.5-1.22.0-1.71.7
Seeking ratio, punishment vs. effort2.13.05.72.0-2.41.3-2.32.3-1.80.5-1.11.1
Retroperitoneal fat weight5.523.735.44.5-5.94.0-5.65.6-5.62.5-4.54.5
Reaction time number correct0.20.42.60.20.10.9-0.30.3-0.21.60.0-0.0
Reaction time mean minus median0.20.51.3-0.5-0.1-0.4-0.40.4-0.70.9-1.21.2
Reaction time mean minus median AUC0.10.20.5-0.60.3-0.40.0-0.0-0.30.6-0.70.7
Reaction time num false alarms0.60.81.00.9-1.01.0-1.01.0-1.00.7-0.60.6
Reaction time num false alarms AUC0.00.10.20.4-0.20.4-0.30.3-0.30.3-0.00.0
Reaction time trials correct on left0.20.42.60.20.10.9-0.30.3-0.21.60.0-0.0
Reaction time trials on left0.20.42.50.20.10.8-0.30.3-0.11.60.0-0.0
Reaction time mean0.30.51.20.7-1.10.6-0.90.9-0.60.2-0.40.4
Reaction time mean AUC0.10.20.70.6-0.80.6-0.60.6-0.4-0.0-0.20.2
Median of all reaction times0.30.41.10.9-1.10.7-0.70.7-0.2-0.20.1-0.1
Reaction time omissions0.30.41.2-0.1-0.7-0.3-0.30.3-0.70.3-1.11.1
Reaction time false alarm rate0.10.10.80.3-0.2-0.0-0.10.10.0-0.90.3-0.3
Reaction time premature initiation rate1.92.63.81.1-2.00.3-1.91.9-1.90.7-1.91.9
Reaction time premature initiations1.22.12.70.9-1.60.5-1.71.7-1.61.3-1.61.6
Std. dev. reaction times0.50.92.10.0-0.7-0.1-0.80.8-1.11.0-1.51.5
Reaction time trials completed0.20.42.50.20.10.8-0.30.3-0.11.60.0-0.0
Reaction time trials AUC0.30.52.80.3-0.10.9-0.50.5-0.31.7-0.20.2
Run reversals in cocaine runway, females2.62.65.40.5-1.30.3-1.41.4-2.01.5-2.32.3
Run reversals in cocaine runway, males1.61.63.5-1.91.6-1.21.7-1.70.7-0.5-0.20.2
Latency to leave start box in cocaine runway1.51.84.32.1-1.71.6-1.61.6-0.50.30.5-0.5
Latency to leave start box in cocaine runway, F2.02.35.12.3-2.01.5-2.02.0-0.80.80.2-0.2
Latency to leave start box in cocaine runway, M0.30.30.70.4-0.00.50.2-0.20.5-0.70.8-0.8
Std. dev. time between licks in bursts1.52.02.61.2-1.50.6-1.51.5-1.61.6-1.51.5
Total sessions with >9 infusions1.61.92.8-1.11.4-1.51.3-1.31.7-1.61.2-1.2
Short access day 1 total inactive lever presses0.50.61.2-1.11.0-0.91.1-1.10.5-0.2-0.00.0
Short access day 10 total inactive lever presses0.71.73.91.4-1.42.0-1.11.1-1.31.6-0.60.6
Short access day 1 total infusions1.01.33.8-1.10.9-1.61.0-1.01.0-2.00.5-0.5
Short access day 10 total infusions1.41.83.1-1.31.4-1.81.3-1.31.4-1.70.8-0.8
Short access total infusions2.02.54.4-1.51.6-1.81.6-1.61.7-2.11.1-1.1
Short access day 1 locomotion2.83.55.2-2.12.2-1.92.3-2.31.8-1.80.9-0.9
Short access day 10 total locomotion0.40.81.4-1.01.0-1.20.9-0.90.7-1.20.3-0.3
Short access total locomotion1.01.12.0-0.51.0-0.60.9-0.91.3-1.41.3-1.3
One hour access (0.3 mA shock)0.60.71.9-0.90.7-1.10.8-0.80.5-1.4-0.10.1
Compulsive drug intake0.20.30.80.7-0.30.9-0.20.20.10.50.5-0.5
One hour access (shock baseline)1.42.23.4-1.61.7-1.91.6-1.61.4-1.80.6-0.6
Social response proportion2.22.54.72.2-1.92.0-2.02.0-1.21.0-0.20.2
Social responses2.83.74.61.7-2.11.6-2.12.1-2.22.0-1.71.7
Social time1.21.73.51.8-1.61.9-1.41.4-0.81.0-0.00.0
Soleus weight1.44.26.11.4-2.11.2-2.32.3-2.51.8-2.32.3
Bone: stiffness0.10.21.2-0.1-0.00.20.1-0.10.3-1.10.4-0.4
Tibialis anterior weight0.41.22.10.5-1.20.7-1.11.1-1.40.8-1.51.5
Time to tail flick, vehicle, before self-admin0.20.21.0-0.1-0.1-0.1-0.10.1-0.31.0-0.50.5
Time to tail flick, vehicle, after self-admin0.50.71.6-1.30.9-1.10.9-0.90.20.7-0.50.5
Time to tail flick, test, before self-admin0.50.51.1-1.10.6-1.00.4-0.4-0.1-0.4-0.80.8
Time to tail flick, test, after self-admin0.70.72.4-0.5-0.1-0.6-0.20.2-0.61.5-1.21.2
Delta time to tail flick, vehicle, before/after SA0.90.81.4-1.11.2-1.01.1-1.10.8-0.50.4-0.4
Delta time to tail flick, test, before/after SA0.70.71.91.0-0.91.1-0.80.8-0.51.4-0.10.1
Tibia length0.61.62.3-1.31.3-1.51.2-1.21.5-1.31.0-1.0
Ambulatory time before self-admin0.10.10.2-0.10.20.20.4-0.40.3-0.40.3-0.3
Ambulatory time after self-admin0.40.41.10.40.21.00.2-0.20.40.31.1-1.1
Bone: tissue strength0.90.92.20.7-0.11.3-0.10.10.5-1.51.3-1.3
Total heroin consumption0.10.20.60.2-0.40.4-0.00.0-0.4-0.8-0.40.4
Bone: trabecular number0.10.20.50.10.30.40.3-0.30.4-0.50.7-0.7
Bone: trabecular spacing0.20.30.6-0.50.5-0.70.6-0.60.7-0.10.5-0.5
Bone: trabecular thickness1.21.53.5-0.1-0.70.5-0.80.8-1.61.4-1.91.9
Bone: trabecular tissue density3.34.86.21.9-2.32.3-2.32.3-2.52.1-1.91.9
Water consumed over 24 hours0.30.41.10.8-0.51.1-0.50.5-0.70.7-0.30.3
Number of responses in last shaping day1.71.94.62.0-2.11.1-1.71.7-1.1-0.4-0.30.3