Hub : Genes

Ndufb5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression Ndufb5 0.14 0.09 1.6e-03 0.11 0.16 0.07 0.1 1.4e-03 1.2e-04 1.0e-02 2.7e-03
2 BLA gene expression Ndufb5 0.1 0.07 1.3e-04 0.08 0.07 0.05 0.06 6.6e-05 2.1e-04 9.3e-04 6.3e-04
3 RMTg gene expression Ndufb5 0.1 0.08 9.4e-03 0.02 0.08 0.06 0.06 8.0e-02 4.7e-03 1.4e-02 1.0e-02
4 PL mRNA stability Ndufb5 0.09 0.06 1.8e-05 0.03 0.04 0.04 0.03 4.8e-04 1.2e-05 5.4e-05 1.5e-04
5 pVTA gene expression Ndufb5 0.08 0.05 5.7e-06 0.04 0.05 0.03 0.04 5.2e-04 1.0e-04 1.3e-03 3.2e-04
6 PL gene expression Ndufb5 0.04 0.03 2.5e-04 0.02 0.03 0.02 0.02 1.3e-03 4.9e-04 5.8e-03 1.1e-03
7 Adipose gene expression Ndufb5 0.09 0.05 5.6e-08 0.07 0.04 0.04 0.06 1.5e-08 5.4e-05 4.4e-05 4.7e-07
8 Brain mRNA stability Ndufb5 0.22 0.09 0.0e+00 0.21 0.21 0.21 0.21 1.3e-19 1.7e-19 3.4e-19 3.0e-19
9 Brain gene expression Ndufb5 0.08 0.06 8.6e-06 0.06 0.05 0.05 0.05 4.0e-06 2.0e-05 1.8e-05 1.2e-05
10 Adipose mRNA stability Ndufb5 0.04 0.03 7.2e-04 0.03 0.02 0.02 0.02 4.7e-04 1.6e-03 3.6e-03 1.6e-03
11 Liver gene expression Ndufb5 0.24 0.1 0.0e+00 0.14 0.14 0.15 0.14 1.4e-15 2.0e-15 2.3e-16 8.3e-15
12 NAcc gene expression Ndufb5 0.15 0.13 2.1e-06 0.03 0.04 0.04 0.03 7.0e-06 2.7e-06 7.2e-07 1.1e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density1.62.76.62.52.62.2-1.72.01.61.3-1.21.1-0.10.50.7
Area under the delay curve1.11.34.51.01.01.1-1.21.01.01.0-0.91.2-2.11.00.3
BMI with tail0.62.13.40.71.11.3-1.01.61.51.8-1.51.7-1.81.80.8
BMI without tail0.61.72.30.91.21.4-1.31.51.51.5-1.41.2-1.41.40.6
Body weight0.10.63.90.30.40.4-0.20.60.40.4-0.30.6-2.00.5-1.1
Weight adjusted by age1.42.24.2-1.0-1.1-1.41.6-1.5-1.6-1.41.4-1.52.1-1.8-0.7
Bone surface0.20.41.40.60.6-0.10.6-0.1-0.4-0.60.7-0.81.2-0.9-0.5
Bone volume0.40.72.21.00.80.10.4-0.1-0.5-0.70.9-0.81.5-1.2-0.6
Breakpoint value in progressive ratio session2.22.63.61.31.61.7-1.41.91.81.9-1.81.5-1.91.70.1
Number of licking bursts2.03.34.80.91.31.8-1.92.02.12.1-2.21.9-2.02.21.0
Context. condit. distance diff. score1.82.26.02.42.32.0-1.81.61.30.9-1.00.90.10.10.5
Locomotion velocity, session 10.70.73.2-1.8-1.4-1.01.1-0.5-0.30.30.10.20.70.70.2
Locomotion distance, session 10.20.31.0-1.0-0.7-0.40.40.10.20.5-0.40.6-0.10.70.6
Locomotion velocity, session 21.01.15.5-2.3-1.8-1.21.2-0.5-0.20.5-0.10.30.60.8-0.2
Locomotion distance, session 20.40.62.2-1.5-1.2-1.01.0-0.6-0.50.00.3-0.10.40.30.3
Locomotion velocity, session 30.00.00.2-0.2-0.0-0.10.20.00.00.2-0.0-0.00.40.30.4
Locomotion distance, session 30.10.20.6-0.8-0.5-0.30.1-0.10.10.4-0.30.0-0.40.7-0.1
Stereotopy head waving bouts, day 30.10.10.7-0.3-0.3-0.20.2-0.1-0.10.00.10.20.90.20.8
Stereotopy head waving duration, day 30.70.81.80.90.91.0-0.91.00.90.8-0.81.0-0.10.61.4
Locomotion velocity, session 71.21.33.4-0.8-0.7-1.21.6-0.9-1.1-0.91.1-1.11.0-0.7-1.8
Locomotion distance, session 70.91.21.9-0.8-0.9-1.11.2-1.1-1.1-1.01.1-1.21.1-0.9-1.4
Stereotopy head waving bouts, day 71.21.32.10.40.71.1-1.21.21.31.4-1.41.3-0.81.11.4
Stereotopy head waving duration, day 71.92.33.20.91.21.5-1.51.71.81.8-1.81.7-0.81.41.6
Locomotion velocity, session 82.42.84.31.31.51.8-1.61.91.91.9-1.72.1-1.21.71.3
Locomotion distance, session 80.20.31.11.01.00.7-0.40.60.40.3-0.20.40.6-0.10.3
Degree of sensitization distance2.22.23.4-0.6-0.9-1.31.4-1.5-1.6-1.71.7-1.71.7-1.8-1.5
Degree of sensitization stereotypy2.83.14.11.21.51.8-2.01.92.01.9-2.01.8-1.51.51.8
Conditioned locomotion0.30.30.90.40.2-0.1-0.1-0.4-0.5-0.80.6-0.90.9-0.9-0.0
Cocaine response after cond. corrected0.20.20.70.2-0.2-0.2-0.2-0.6-0.5-0.80.6-0.30.1-0.80.2
Cocaine response after cond. not corrected0.60.71.6-0.3-0.7-0.80.5-1.0-1.0-1.21.0-0.80.5-1.3-0.1
Cocaine response before conditioning0.10.10.6-0.1-0.1-0.30.8-0.2-0.3-0.20.2-0.60.4-0.4-0.3
Saline control response0.60.81.6-0.4-0.5-0.91.3-0.8-1.0-0.81.1-1.01.2-0.6-0.8
Bone: connectivity density1.21.93.51.61.91.7-1.31.71.61.4-1.41.0-0.60.90.7
Bone: cortical apparent density0.10.10.60.20.40.3-0.10.30.30.4-0.2-0.20.80.0-0.4
Bone: cortical area1.21.93.50.40.1-0.71.4-0.9-1.3-1.51.7-1.91.8-1.7-1.7
Bone: cortical porosity0.10.11.00.40.30.1-0.10.10.00.00.00.1-0.20.21.0
Bone: cortical porosity0.10.10.20.50.3-0.10.3-0.1-0.3-0.30.4-0.2-0.1-0.10.5
Bone: cortical thickness0.61.02.30.80.4-0.20.7-0.5-0.8-1.21.2-1.51.3-1.5-1.1
Bone: cortical thickness0.20.20.4-0.7-0.5-0.10.10.20.40.6-0.50.6-0.20.70.1
Bone: cortical tissue density0.10.10.40.20.50.3-0.20.30.30.4-0.3-0.10.70.1-0.4
Condit. Reinf. active minus inactive responses1.41.62.9-1.5-1.4-1.51.6-1.4-1.3-1.01.2-1.1-0.3-0.4-1.7
Condit. Reinf. active-inactive response ratio1.51.62.3-1.2-1.3-1.51.4-1.5-1.5-1.31.4-1.4-0.1-0.8-1.4
Condit. Reinf. active responses0.81.03.0-1.3-1.0-1.21.7-0.8-0.8-0.30.7-0.7-0.50.2-1.7
Condit. Reinf. inactive responses0.20.30.7-0.00.30.10.60.70.50.8-0.40.5-0.20.8-0.5
Incentive salience index mean1.51.93.1-1.7-1.6-1.71.7-1.5-1.4-1.11.3-1.1-0.2-0.5-1.5
Condit. Reinf. lever presses0.40.61.6-1.1-1.0-1.01.3-0.7-0.7-0.50.7-0.4-0.1-0.1-0.7
Condit. Reinf. active minus inactive responses1.31.74.3-1.0-0.9-1.41.7-1.3-1.4-1.21.4-1.4-0.3-0.9-2.1
Condit. Reinf. active-inactive response ratio1.41.64.2-0.8-0.9-1.31.2-1.4-1.4-1.41.3-1.4-0.7-0.9-2.0
Condit. Reinf. active responses2.53.47.0-1.9-1.7-2.22.6-1.8-1.9-1.51.8-1.70.9-1.0-2.4
Condit. Reinf. inactive responses0.81.02.9-1.7-1.5-1.31.6-0.7-0.6-0.20.4-0.21.10.1-0.6
Condit. Reinf. lever presses0.50.71.3-0.4-0.5-0.81.0-0.8-0.9-0.81.0-0.8-0.2-1.0-1.1
Condit. Reinf. lever reinforcers received2.43.36.8-1.8-1.7-2.12.6-1.8-1.9-1.51.8-1.60.9-1.1-2.4
Conditioned reinforcement - actives0.20.41.4-1.2-1.0-0.70.7-0.3-0.10.4-0.20.00.00.8-0.7
Conditioned reinforcement - inactives0.10.10.8-0.4-0.3-0.10.10.00.10.9-0.20.40.00.60.1
Conditioned locomotion0.30.41.7-1.3-1.0-0.60.8-0.10.10.7-0.40.30.00.7-0.2
Patch foraging indifference point 0 sec1.22.22.91.31.61.7-1.71.71.71.5-1.61.6-1.40.90.6
Patch foraging indifference point AUC2.13.14.90.71.31.5-1.51.92.02.0-2.12.2-1.52.21.6
Delay disc. indifference point, 0s delay0.40.41.3-0.6-0.6-0.70.9-0.6-0.6-0.40.6-0.4-0.0-0.1-1.1
Delay disc. indifference point, 16s delay1.21.33.61.31.21.3-1.21.21.11.0-1.00.9-1.90.9-0.2
Delay disc. indifference point, 2s delay0.50.62.10.90.70.8-0.80.70.60.6-0.50.8-1.50.40.0
Delay disc. indifference point, 24s delay0.91.01.61.31.21.2-1.21.01.01.0-1.00.7-0.80.40.7
Delay disc. indifference point, 4s delay0.60.61.80.30.40.6-0.70.70.80.7-0.71.2-1.30.90.3
Delay disc. indifference point, 8s delay0.60.72.90.40.40.6-1.00.50.70.6-0.60.9-1.70.90.6
Indifference point function ln k1.52.75.2-0.6-1.1-1.41.2-1.8-1.8-2.11.9-1.80.9-2.3-1.8
Indifference point function log k1.52.75.2-0.6-1.1-1.41.2-1.8-1.8-2.11.9-1.80.9-2.3-1.8
Patch foraging total patch changes 0 sec1.12.12.71.21.51.6-1.61.61.61.5-1.61.6-1.30.90.9
Patch foraging total patch changes 12 sec1.82.33.01.01.41.5-1.61.61.71.6-1.71.6-1.21.51.7
Patch foraging total patch changes 18 sec1.52.33.60.71.11.4-1.51.61.71.7-1.81.9-1.61.61.0
Patch foraging total patch changes 24 sec3.15.37.12.02.42.5-2.22.72.52.4-2.52.6-2.12.01.4
Patch foraging total patch changes 6 sec4.56.88.92.32.82.9-2.73.02.92.7-2.92.8-1.32.32.3
Patch foraging time to switch 0 sec0.10.20.5-0.2-0.3-0.40.3-0.5-0.5-0.50.5-0.70.3-0.6-0.6
Patch foraging water rate 0 sec0.30.51.01.01.00.9-0.80.80.70.4-0.50.70.20.11.0
Patch foraging water rate 12 sec0.10.21.30.20.0-0.10.2-0.2-0.2-0.30.2-0.41.1-0.70.1
Patch foraging water rate 18 sec0.10.21.0-0.6-0.6-0.30.4-0.2-0.10.10.00.21.0-0.00.5
Patch foraging water rate 24 sec1.01.32.31.31.51.4-0.91.51.31.3-1.11.20.10.80.4
Patch foraging water rate 6 sec0.00.00.00.20.20.2-0.10.20.20.2-0.20.00.10.00.1
Seeking ratio, delayed vs. immediate footshock0.20.31.00.80.70.4-0.10.30.20.2-0.2-0.4-0.70.2-1.0
Distance traveled before self-admin1.62.12.81.31.41.6-1.51.61.51.6-1.41.4-1.71.01.1
Distance traveled after self-admin0.70.92.30.40.60.8-0.71.11.11.3-1.00.9-1.50.90.0
Extensor digitorum longus weight0.20.83.00.20.60.7-0.21.11.01.3-0.90.7-1.71.1-0.1
Bone: elastic displacement0.20.20.70.3-0.0-0.0-0.2-0.3-0.3-0.50.2-0.4-0.7-0.8-0.6
Bone: elastic work1.92.54.5-0.4-0.7-1.41.5-1.6-1.8-2.01.9-1.81.4-2.1-1.5
Bone: endosteal estimation0.81.83.6-0.9-0.8-1.41.9-1.1-1.4-1.31.6-1.20.9-1.2-1.8
Bone: endosteal perimeter0.51.11.9-1.0-1.0-1.21.4-1.0-1.1-1.01.2-0.91.2-0.8-0.6
Epididymis fat weight0.10.40.7-0.5-0.7-0.60.5-0.6-0.6-0.50.5-0.3-0.8-0.7-0.8
Delta time in closed arm before/after self-admin0.40.31.51.21.00.7-0.40.50.2-0.30.10.2-0.5-0.40.3
Delta time in open arm before/after self-admin0.20.21.1-0.5-0.4-0.2-0.3-0.20.00.0-0.30.1-1.00.4-0.2
Diff in mean of infusions in LGA sessions0.10.20.50.50.30.10.1-0.1-0.2-0.50.3-0.3-0.6-0.7-0.4
Delay discount exponential model param1.41.64.7-1.1-1.1-1.31.4-1.2-1.2-1.11.1-1.32.2-1.1-0.6
Extinction: sum of active levers before priming2.52.711.3-0.8-1.0-1.41.7-1.4-1.6-1.41.4-1.9-0.6-1.4-3.4
Active lever presses in extinction session 60.60.62.90.50.50.6-0.60.60.60.8-0.60.4-1.71.0-0.3
Bone: final force1.11.73.3-0.3-0.4-1.11.8-1.0-1.3-1.31.7-1.71.4-1.3-1.4
Bone: final moment0.91.52.7-0.0-0.1-0.91.6-0.8-1.2-1.21.6-1.61.3-1.3-1.5
Food consumed during 24 hour testing period0.10.20.70.0-0.1-0.10.1-0.3-0.3-0.30.4-0.4-0.6-0.4-0.8
Glucose0.40.71.3-1.1-1.1-1.00.7-1.0-0.8-0.70.7-0.70.8-0.60.3
Heart weight0.10.21.70.00.20.10.10.30.20.3-0.10.2-1.30.4-0.8
Delay discount hyperbolic model param1.31.44.6-1.0-1.0-1.21.3-1.1-1.1-1.01.0-1.32.2-1.0-0.6
Intermittent access intake day 1-15 change0.71.43.00.81.01.2-1.21.21.31.7-1.21.20.01.50.8
Intermittent access intake escalation1.02.14.30.81.11.4-1.51.51.62.1-1.71.60.01.81.1
Intermittent access intake escalation 20.00.00.10.20.20.1-0.00.10.10.2-0.0-0.00.00.1-0.2
Intermitt. access day 1 inactive lever presses0.00.10.4-0.0-0.1-0.30.5-0.4-0.5-0.20.6-0.40.0-0.4-0.2
Intermitt. access day 15 inactive lever presses0.10.31.0-1.0-0.9-0.40.0-0.20.00.3-0.30.40.00.50.8
Intermitt. access escalation Index0.20.21.00.40.2-0.10.2-0.3-0.4-1.00.6-0.50.0-0.80.0
Intermittent access day 1 total infusions2.54.08.6-2.9-2.9-2.62.5-2.2-2.0-1.41.5-1.60.0-0.8-1.5
Intermittent access day 15 total infusions0.50.72.9-0.9-0.60.0-0.20.50.71.5-1.01.00.01.70.2
Intermittent access terminal intake (last 3 days)0.60.72.6-1.6-1.4-1.11.1-0.8-0.60.20.3-0.40.00.4-0.5
Intermittent access total infusions0.70.83.5-1.9-1.5-0.90.8-0.4-0.10.8-0.40.30.01.2-0.3
Intermittent access day 1 locomotion1.31.74.1-2.0-1.8-1.71.9-1.2-1.1-0.70.8-0.80.0-0.2-1.4
Intermittent access day 15 total locomotion0.50.93.6-0.30.10.4-0.10.90.91.9-1.11.00.01.70.2
Intermittent access total locomotion0.70.83.0-1.0-0.6-0.10.20.50.71.4-1.01.00.01.70.1
Intermittent access standard deviation0.10.30.60.50.50.6-0.60.60.60.8-0.50.50.00.40.2
Left kidney weight0.21.23.31.00.6-0.10.4-0.5-0.9-1.31.3-1.30.5-1.7-1.8
Right kidney weight0.21.13.21.81.71.3-1.01.10.80.3-0.40.8-1.1-0.1-0.6
Cocaine induced anxiety0.10.20.7-0.8-0.8-0.60.6-0.5-0.4-0.10.3-0.10.00.30.0
Post-drug Anxiety0.20.20.7-0.8-0.7-0.60.7-0.4-0.4-0.30.2-0.10.00.3-0.0
Baseline Anxiety0.00.00.10.00.10.2-0.20.20.20.1-0.30.20.00.00.2
Tail length0.10.20.6-0.0-0.2-0.2-0.1-0.5-0.4-0.70.4-0.7-0.2-0.8-0.5
Length with tail0.41.84.7-0.7-1.0-1.21.1-1.3-1.4-1.61.4-1.4-0.3-1.5-2.2
Length without tail0.31.04.4-0.4-0.6-0.70.8-0.6-0.7-0.80.8-0.4-1.8-0.5-2.1
Times rat made contact with spout0.60.71.5-1.2-1.2-1.00.6-1.0-0.8-0.60.6-0.80.3-0.3-0.8
Lifetime Intake0.70.94.1-2.0-1.7-1.21.0-0.6-0.30.3-0.10.10.00.9-0.2
Liver weight, left1.21.94.5-2.1-1.9-1.81.7-1.4-1.2-1.01.1-1.00.4-0.3-1.4
Liver weight, right0.61.16.3-0.3-0.4-0.70.8-0.9-1.0-1.21.1-0.72.5-0.8-0.2
Locomotor activity3.35.18.1-1.7-1.9-2.52.8-2.4-2.6-2.42.5-2.52.0-1.9-1.4
Locomotor testing distance2.03.57.3-1.6-1.7-2.12.7-1.9-2.0-1.71.9-2.11.2-1.3-1.9
Locomotor testing rearing0.40.91.9-0.3-0.5-0.81.3-0.7-1.0-0.81.1-1.41.3-0.6-0.8
Locomotion in novel chamber0.30.41.6-0.8-0.5-0.0-0.10.30.60.8-0.70.4-0.81.30.1
Locomotion in novel chamber post-restriction0.10.20.80.50.30.10.1-0.0-0.2-0.30.50.30.7-0.50.9
Fecal boli incidents, locomotor time 10.71.01.5-1.2-1.2-1.20.8-1.2-1.1-1.00.9-1.20.5-0.8-0.6
Change in fecal boli incidents, locomotor task0.50.51.10.40.50.7-0.60.80.91.0-0.80.5-0.80.70.5
Time >=10cm from walls, locomotor time 10.10.10.3-0.0-0.1-0.30.3-0.4-0.5-0.60.5-0.3-0.0-0.4-0.2
Bouts of movement, locomotor time 11.01.23.10.1-0.0-0.71.0-0.9-1.1-1.31.1-1.11.8-1.6-0.9
Total resting periods, locomotor time 10.80.92.10.0-0.2-0.60.7-0.9-1.0-1.21.0-1.11.4-1.4-0.5
Rest time, locomotor task time 10.50.61.3-1.1-1.1-0.90.6-0.8-0.6-0.40.5-1.0-0.1-0.3-0.8
Distance moved, locomotor task time 11.01.53.21.01.11.2-1.01.31.11.0-1.11.8-0.81.11.8
Vertical activity count, locomotor time 10.61.43.11.21.11.2-1.21.11.00.9-0.91.6-0.61.11.8
Time >=10cm from walls, locomotor time 20.10.20.8-0.4-0.4-0.30.2-0.4-0.2-0.10.1-0.6-0.90.0-0.8
Bouts of movement, locomotor time 20.20.31.40.60.50.3-0.50.00.0-0.3-0.10.01.2-0.70.4
Total resting periods, locomotor time 20.10.21.60.50.40.2-0.3-0.1-0.1-0.4-0.0-0.11.3-0.70.3
Rest time, locomotor task time 20.00.00.20.30.20.1-0.10.00.00.0-0.1-0.40.2-0.1-0.3
Distance moved, locomotor task time 20.30.31.8-0.4-0.2-0.10.10.20.20.3-0.40.8-1.30.70.4
Vertical activity count, locomotor time 20.30.41.3-1.1-0.9-0.40.3-0.00.20.5-0.30.5-1.11.00.2
Light reinforcement 10.71.62.9-0.4-0.7-1.21.5-1.4-1.6-1.41.7-1.60.8-1.3-1.1
Light reinforcement 20.00.10.2-0.3-0.4-0.30.3-0.3-0.3-0.20.2-0.1-0.1-0.00.1
Bone: marrow area0.71.43.0-0.8-0.7-1.21.7-1.0-1.3-1.11.4-1.00.8-1.1-1.7
Bone: maximum diameter0.40.83.20.20.0-0.50.9-0.5-0.8-0.91.1-1.11.8-1.1-0.7
Bone: maximum force1.73.14.7-0.6-0.8-1.52.1-1.5-1.9-1.92.2-2.21.8-1.9-1.8
Bone: maximum moment1.62.94.7-0.4-0.5-1.42.0-1.4-1.8-1.92.1-2.21.7-1.9-1.9
Mean time between licks in bursts1.23.06.4-0.7-1.1-1.51.4-1.8-1.9-2.22.0-1.81.5-2.5-1.2
Mean num. licks in bursts2.03.04.1-1.4-1.6-1.91.7-2.0-2.0-1.91.9-1.81.5-1.8-1.0
Cd content in liver1.11.24.0-1.9-2.0-1.41.0-1.2-0.9-0.50.5-0.60.8-0.3-0.4
Co content in liver0.30.31.1-0.7-0.5-0.1-0.20.10.40.6-0.60.4-1.10.90.0
Cu content in liver0.10.20.4-0.6-0.6-0.50.2-0.5-0.4-0.40.4-0.20.3-0.20.1
Fe content in liver0.10.10.3-0.5-0.5-0.40.1-0.4-0.2-0.20.1-0.20.10.20.2
K content in liver0.80.82.11.41.10.3-0.0-0.2-0.5-1.01.0-0.81.0-1.5-0.4
Mg content in liver1.11.13.11.20.8-0.00.2-0.6-0.9-1.41.4-1.20.6-1.8-1.1
Mn content in liver0.30.30.60.80.50.1-0.1-0.3-0.4-0.80.7-0.80.6-0.6-0.4
Na content in liver0.50.51.20.60.80.8-0.50.90.80.8-0.71.10.10.60.8
Rb content in liver0.30.41.40.80.90.6-0.70.50.50.1-0.40.3-1.2-0.00.1
Se content in liver0.50.61.0-0.9-1.0-0.90.7-0.9-0.8-0.70.7-0.60.9-0.3-0.2
Sr content in liver1.00.92.0-0.20.10.5-0.60.81.01.2-1.21.1-1.41.40.4
Zn content in liver0.20.20.4-0.1-0.3-0.30.1-0.5-0.5-0.60.6-0.4-0.4-0.5-0.5
Bone: minimum diameter2.75.08.4-0.5-0.9-1.92.5-2.0-2.4-2.62.9-2.61.9-2.5-2.8
Time in familiar zone, hab. session 10.20.20.4-0.6-0.5-0.1-0.20.10.30.4-0.40.3-0.40.40.6
Time in novel zone, hab. session 11.21.23.21.81.71.3-1.01.20.90.8-0.70.80.00.60.6
Total zone transitions, hab. session 10.40.51.70.70.80.7-0.40.80.60.7-0.60.7-1.30.80.3
Total locomotion distance, hab. session 11.42.04.11.92.01.6-1.01.71.41.3-1.11.3-1.01.11.0
Locomotion velocity, hab. session 11.21.73.61.81.91.5-1.01.61.21.1-1.01.1-1.20.90.8
Time in familiar zone, hab. session 20.30.31.4-0.1-0.2-0.40.4-0.4-0.5-0.50.6-0.61.2-0.50.7
Time in novel zone, hab. session 21.21.22.51.11.21.2-1.01.21.11.1-1.10.9-1.60.9-0.3
Total zone transitions, hab. session 20.10.10.2-0.3-0.1-0.00.10.20.20.4-0.20.4-0.20.40.3
Total locomotion distance, hab. session 20.10.20.30.30.40.4-0.20.50.40.5-0.40.5-0.40.40.6
Locomotion velocity, hab. session 20.10.10.30.00.20.20.00.30.30.4-0.30.4-0.10.30.6
Novel to familiar place preference ratio5.15.69.53.13.02.9-2.82.52.31.9-2.11.8-2.11.41.8
Novelty place preference6.57.012.13.53.43.3-3.12.82.62.1-2.32.1-2.11.52.0
Time in novel zone, NPP test7.07.513.43.73.63.4-3.23.02.72.2-2.42.1-2.11.62.0
Total zone transitions, NPP test0.50.72.6-1.6-1.3-1.11.2-0.6-0.5-0.10.30.00.60.5-0.1
Total locomotion distance, NPP test0.20.20.8-0.9-0.7-0.60.6-0.2-0.20.10.10.20.50.50.6
Locomotion velocity, NPP test0.30.41.2-1.1-0.9-0.91.0-0.5-0.5-0.20.4-0.10.70.20.4
Intraocular pressure0.71.01.5-1.1-1.0-1.21.2-1.1-1.1-0.91.1-0.80.1-0.5-1.2
Delta distance traveled before/after self-admin0.40.41.3-1.1-1.0-0.90.9-0.7-0.6-0.20.5-0.40.2-0.1-0.5
Delta ambulatory time before/after self-admin0.10.20.7-0.8-0.6-0.50.5-0.3-0.20.00.1-0.1-0.30.3-0.5
Parametrial fat weight0.40.92.5-1.1-1.0-1.11.5-0.8-0.9-0.50.7-0.4-0.2-0.3-1.6
Pavlov. Cond. lever latency0.60.82.41.51.41.1-1.00.90.70.5-0.60.40.2-0.00.6
Pavlov. Cond. magazine entry latency0.10.11.0-0.2-0.10.0-0.10.10.10.2-0.10.4-1.00.4-0.4
Pavlov. Cond. change in total contacts0.20.20.7-0.9-0.7-0.50.2-0.3-0.1-0.00.10.3-0.30.50.0
Pavlov. Cond. index score0.30.31.2-1.1-0.8-0.40.2-0.10.10.3-0.20.6-0.80.8-0.1
Pavlov. Cond. latency score0.30.41.9-1.4-1.2-0.80.6-0.6-0.4-0.10.20.0-0.40.3-0.4
Pavlov. Cond. lever contacts0.81.02.4-1.6-1.4-1.31.2-1.1-0.9-0.70.8-0.6-0.0-0.3-0.9
Pavlov. Cond. magazine entry number0.81.02.50.1-0.2-0.60.8-0.8-1.0-1.11.0-1.41.6-1.5-0.4
Pavlov. Cond. intertrial magazine entries0.40.41.0-0.2-0.4-0.60.4-0.7-0.7-0.90.7-1.00.4-1.0-0.4
Pavlov. Cond. lever-magazine prob. diff.0.20.30.8-0.9-0.7-0.30.1-0.00.20.4-0.30.6-0.80.7-0.0
Pavlov. Cond. response bias0.50.62.3-0.5-0.10.2-0.40.50.60.8-0.71.0-1.51.1-0.0
Pavlov. Cond. lever latency0.20.30.5-0.5-0.6-0.60.4-0.6-0.6-0.60.5-0.60.7-0.3-0.3
Pavlov. Cond. magazine entry latency0.30.40.80.10.30.6-0.90.50.70.6-0.70.5-0.60.40.9
Pavlov. Cond. change in total contacts0.20.30.9-1.0-0.7-0.70.7-0.5-0.4-0.10.4-0.2-0.70.1-0.5
Pavlov. Cond. index score0.20.31.0-0.10.20.4-0.40.50.60.7-0.60.7-1.00.70.3
Pavlov. Cond. latency score0.20.31.1-0.20.10.3-0.40.40.60.6-0.50.6-1.00.70.3
Pavlov. Cond. lever contacts0.20.30.50.60.70.7-0.50.70.60.7-0.50.7-0.40.30.5
Pavlov. Cond. magazine entry number0.60.81.4-0.2-0.6-0.80.9-0.9-1.0-1.01.0-0.91.2-1.0-0.5
Pavlov. Cond. intertrial magazine entries0.20.41.2-0.2-0.3-0.61.1-0.4-0.6-0.40.5-0.50.5-0.4-1.1
Pavlov. Cond. lever-magazine prob. diff.0.20.30.9-0.20.20.3-0.40.50.60.7-0.60.7-1.00.70.3
Pavlov. Cond. response bias0.20.20.30.40.60.5-0.40.60.60.6-0.50.5-0.50.30.4
Time in closed arm before self-admin0.30.41.00.80.80.7-0.60.60.50.6-0.30.31.00.10.4
Time in closed arm after self-admin0.30.31.11.10.80.5-0.30.2-0.1-0.40.4-0.10.6-0.70.5
Time in open arm before self-admin0.30.31.00.30.40.5-0.40.60.50.7-0.60.6-1.00.60.6
Time in open arm after self-admin0.40.42.5-0.10.00.3-0.50.30.50.5-0.70.5-1.60.7-0.2
Bone: periosteal estimation1.32.84.7-0.4-0.5-1.42.1-1.3-1.7-1.82.1-1.81.7-1.9-2.2
Bone: periosteal perimeter1.11.93.9-0.2-0.5-1.11.5-1.1-1.4-1.61.7-1.72.0-1.7-1.0
Bone: post-yield work0.40.62.3-1.5-1.5-1.00.4-0.9-0.6-0.40.4-0.7-0.30.2-0.3
Progressive ratio test 1 active lever presses1.51.94.5-2.1-1.9-1.82.0-1.3-1.2-0.70.8-0.80.0-0.1-1.6
Progressive ratio test 1 breakpoint1.72.14.8-2.2-2.0-1.92.1-1.3-1.2-0.70.9-0.90.0-0.2-1.6
Progressive ratio test 1 inactive lever presses0.60.82.8-1.7-1.5-1.21.2-0.8-0.60.10.3-0.30.00.5-0.6
Progressive ratio test 2 active lever presses1.21.44.6-1.6-1.0-0.1-0.00.61.01.7-1.51.50.02.10.3
Progressive ratio test 2 breakpoint1.31.54.8-1.5-0.9-0.0-0.10.71.11.8-1.61.50.02.20.4
Progressive ratio test 2 inactive lever presses0.30.41.4-0.9-0.6-0.1-0.10.30.51.0-0.80.80.01.20.2
Incentive Sensitization - Responses0.71.03.1-0.9-0.50.1-0.30.70.91.8-1.31.30.01.70.4
Incentive Sensitization - Breakpoint0.91.13.4-0.9-0.50.2-0.40.71.01.8-1.41.40.01.80.4
Sum of active levers in priming session hrs 5-61.51.42.9-1.7-1.5-1.41.4-1.2-1.0-0.70.7-1.1-0.5-0.3-1.6
Progressive ratio0.00.10.20.40.30.3-0.00.30.20.4-0.20.0-0.10.5-0.2
Food seeking constrained by brief footshock0.10.10.60.80.60.3-0.20.2-0.0-0.10.2-0.3-0.50.1-0.4
Seeking ratio, punishment vs. effort0.30.40.80.70.70.8-0.90.70.60.4-0.50.6-0.50.20.6
Retroperitoneal fat weight0.20.72.8-0.9-0.7-0.81.2-0.4-0.5-0.30.4-0.1-1.2-0.3-1.7
Reaction time number correct0.91.76.4-2.5-2.3-1.61.4-1.1-0.7-0.20.3-0.21.20.10.5
Reaction time mean minus median0.20.55.8-0.2-0.20.0-0.5-0.10.1-0.0-0.2-0.1-2.40.1-0.5
Reaction time mean minus median AUC0.30.74.20.20.30.6-0.90.50.70.6-0.80.5-2.10.50.1
Reaction time num false alarms0.00.10.60.20.10.00.10.10.00.10.0-0.2-0.80.1-0.1
Reaction time num false alarms AUC0.00.00.1-0.1-0.1-0.10.2-0.00.00.1-0.1-0.1-0.30.0-0.1
Reaction time trials correct on left0.91.76.4-2.5-2.3-1.61.4-1.1-0.7-0.20.3-0.21.20.10.5
Reaction time trials on left0.91.86.5-2.6-2.3-1.71.5-1.2-0.8-0.30.4-0.31.1-0.00.4
Reaction time mean1.11.82.8-1.5-1.7-1.41.0-1.5-1.3-1.21.0-1.2-1.7-0.6-1.7
Reaction time mean AUC0.91.42.8-1.3-1.5-1.30.8-1.4-1.1-1.10.9-1.1-1.7-0.6-1.3
Median of all reaction times1.21.72.7-1.5-1.7-1.51.1-1.5-1.3-1.21.0-1.2-1.3-0.6-1.5
Reaction time omissions2.53.76.1-0.7-1.2-1.71.4-2.2-2.2-2.52.4-2.1-1.1-2.3-2.2
Reaction time false alarm rate0.40.61.61.31.20.9-0.70.70.60.4-0.40.2-1.00.2-0.1
Reaction time premature initiation rate0.50.71.61.31.01.0-1.00.70.60.1-0.40.41.2-0.31.1
Reaction time premature initiations0.20.42.8-0.2-0.30.0-0.20.00.20.0-0.20.31.7-0.21.2
Std. dev. reaction times0.40.87.2-0.5-0.5-0.3-0.2-0.4-0.2-0.20.1-0.3-2.70.1-1.0
Reaction time trials completed0.91.86.5-2.6-2.3-1.71.5-1.2-0.8-0.30.4-0.31.1-0.00.4
Reaction time trials AUC0.91.76.1-2.5-2.3-1.71.5-1.2-0.9-0.40.5-0.41.2-0.10.3
Run reversals in cocaine runway, females0.70.71.30.20.50.8-0.80.91.11.1-0.91.00.01.11.0
Run reversals in cocaine runway, males0.20.20.6-0.8-0.6-0.50.5-0.2-0.10.00.00.3-0.40.3-0.8
Latency to leave start box in cocaine runway0.10.10.3-0.3-0.3-0.30.1-0.4-0.4-0.50.4-0.30.1-0.4-0.1
Latency to leave start box in cocaine runway, F0.10.10.2-0.1-0.2-0.2-0.1-0.3-0.3-0.40.40.00.4-0.20.4
Latency to leave start box in cocaine runway, M0.20.20.8-0.2-0.2-0.30.3-0.4-0.4-0.40.4-0.6-0.5-0.4-0.9
Std. dev. time between licks in bursts0.81.02.3-0.2-0.5-0.80.9-1.0-1.2-1.31.3-1.20.7-1.5-0.7
Total sessions with >9 infusions2.42.95.6-2.4-2.3-2.22.2-1.9-1.7-1.31.4-1.40.0-0.8-1.2
Short access day 1 total inactive lever presses1.21.63.00.71.11.3-1.01.61.51.7-1.51.70.01.50.4
Short access day 10 total inactive lever presses1.02.34.82.22.22.0-1.71.81.61.1-1.31.30.00.80.7
Short access day 1 total infusions0.50.61.9-1.4-1.2-1.01.1-0.7-0.6-0.60.4-0.30.0-0.2-0.4
Short access day 10 total infusions1.62.05.5-2.3-2.2-1.91.9-1.5-1.3-0.50.9-1.00.00.0-1.0
Short access total infusions1.82.36.0-2.5-2.3-2.01.9-1.6-1.4-1.01.0-1.00.0-0.4-0.8
Short access day 1 locomotion0.10.20.6-0.5-0.30.00.10.30.40.5-0.60.50.00.80.2
Short access day 10 total locomotion0.00.00.2-0.10.0-0.20.5-0.0-0.10.20.1-0.10.00.2-0.5
Short access total locomotion0.70.92.6-1.6-1.4-1.31.4-0.9-0.7-0.20.5-0.50.00.1-0.6
One hour access (0.3 mA shock)0.40.52.1-0.9-0.6-0.10.00.30.51.1-0.80.80.01.50.2
Compulsive drug intake0.30.30.8-0.4-0.4-0.60.7-0.6-0.6-0.90.6-0.60.0-0.7-0.4
One hour access (shock baseline)0.40.62.3-1.1-0.9-0.20.00.20.51.2-0.80.80.01.50.3
Social response proportion2.02.33.1-1.5-1.7-1.71.4-1.8-1.7-1.71.5-1.60.5-1.6-1.1
Social responses0.10.20.50.20.30.3-0.20.40.40.5-0.30.3-0.40.40.7
Social time3.54.76.9-1.7-2.1-2.31.9-2.6-2.5-2.62.4-2.51.3-2.4-1.1
Soleus weight5.114.936.06.05.85.1-4.34.53.72.9-2.82.5-1.61.52.1
Bone: stiffness0.81.32.7-0.2-0.4-0.91.2-0.9-1.1-1.21.4-1.61.6-1.3-0.8
Tibialis anterior weight0.30.92.00.40.80.8-0.11.31.11.4-1.01.1-1.41.0-0.5
Time to tail flick, vehicle, before self-admin1.61.62.7-1.1-1.5-1.31.0-1.6-1.5-1.31.4-1.60.9-1.2-0.0
Time to tail flick, vehicle, after self-admin0.40.52.0-1.4-1.4-0.80.3-0.8-0.4-0.10.3-0.5-0.70.5-0.3
Time to tail flick, test, before self-admin1.41.43.81.61.51.4-1.51.11.00.6-0.80.8-2.00.10.7
Time to tail flick, test, after self-admin2.93.04.62.12.12.1-2.11.91.91.6-1.61.4-1.11.50.8
Delta time to tail flick, vehicle, before/after SA0.10.10.5-0.7-0.6-0.40.1-0.3-0.10.20.1-0.1-0.10.4-0.3
Delta time to tail flick, test, before/after SA1.31.42.31.01.11.3-1.31.31.31.4-1.31.10.11.50.7
Tibia length3.59.612.0-2.9-3.1-3.53.4-3.3-3.3-3.13.2-2.93.4-2.5-2.2
Ambulatory time before self-admin0.50.71.31.01.01.0-0.91.00.91.1-0.70.7-0.70.40.5
Ambulatory time after self-admin0.20.20.80.20.30.3-0.20.50.50.9-0.40.2-0.60.4-0.5
Bone: tissue strength4.14.27.90.3-0.2-1.41.8-1.9-2.3-2.62.7-2.81.7-2.7-2.1
Total heroin consumption3.94.66.82.22.42.5-2.12.52.32.6-2.12.0-1.31.81.6
Bone: trabecular number6.09.913.33.13.53.6-3.23.63.53.3-3.23.0-1.72.72.6
Bone: trabecular spacing4.66.18.0-2.1-2.4-2.72.4-2.8-2.8-2.62.7-2.62.0-2.3-2.0
Bone: trabecular thickness0.20.30.70.80.70.7-0.70.50.50.2-0.30.10.5-0.40.1
Bone: trabecular tissue density1.01.42.6-0.6-0.9-1.00.7-1.4-1.3-1.51.4-1.31.4-1.60.1
Water consumed over 24 hours0.10.21.5-0.3-0.2-0.20.4-0.1-0.10.00.1-0.3-0.50.1-1.2
Number of responses in last shaping day0.70.81.9-0.00.20.6-0.60.91.01.3-1.11.20.01.40.8