Hub : Genes

Ncln

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL gene expression Ncln 0.72 0.15 0.0e+00 0.4 0.39 0.39 0.4 1.0e-10 2.7e-10 1.8e-10 1.0e-10
2 LHb mRNA stability Ncln 0.64 0.17 1.7e-16 0.52 0.49 0.5 0.51 1.6e-14 1.6e-13 7.0e-14 3.1e-14
3 OFC mRNA stability Ncln 0.46 0.18 9.1e-11 0.4 0.36 0.38 0.39 1.1e-10 2.3e-09 4.6e-10 2.3e-10
4 IL mRNA stability Ncln 0.51 0.19 1.1e-08 0.16 0.16 0.17 0.16 1.0e-04 1.2e-04 5.6e-05 1.3e-04
5 BLA mRNA stability Ncln 0.55 0.17 0.0e+00 0.53 0.53 0.53 0.53 9.8e-33 1.2e-32 6.8e-33 3.1e-33
6 Brain gene expression Ncln 0.61 0.17 0.0e+00 0.49 0.48 0.48 0.48 4.7e-51 5.0e-50 1.8e-50 2.0e-50
7 pVTA mRNA stability Ncln 0.32 0.15 1.9e-12 0.28 0.26 0.27 0.28 1.3e-12 8.1e-12 3.6e-12 1.2e-12
8 Eye mRNA stability Ncln 0.39 0.22 1.8e-03 0.09 0.07 0.07 0.09 2.0e-02 3.1e-02 3.1e-02 1.9e-02
9 Adipose mRNA stability Ncln 0.22 0.11 0.0e+00 0.21 0.2 0.2 0.2 5.4e-23 4.9e-22 3.2e-21 1.5e-21
10 NAcc gene expression Ncln 0.4 0.14 0.0e+00 0.45 0.46 0.46 0.46 4.5e-58 7.8e-59 3.9e-59 2.8e-59
11 LHb gene expression Ncln 0.56 0.18 4.8e-13 0.34 0.37 0.37 0.37 8.5e-09 1.0e-09 9.5e-10 1.3e-09
12 Adipose gene expression Ncln 0.69 0.14 0.0e+00 0.51 0.53 0.53 0.53 1.5e-65 4.6e-69 2.3e-69 7.2e-70
13 NAcc mRNA stability Ncln 0.5 0.18 0.0e+00 0.45 0.44 0.45 0.45 8.8e-58 7.4e-56 1.5e-57 1.3e-57
14 Liver mRNA stability Ncln 0.21 0.11 0.0e+00 0.17 0.2 0.19 0.2 1.2e-18 1.2e-21 6.0e-21 9.8e-22
15 pVTA gene expression Ncln 0.24 0.12 1.0e-09 0.21 0.22 0.21 0.21 1.6e-09 1.0e-09 1.8e-09 1.1e-09
16 RMTg gene expression Ncln 0.13 0.1 5.8e-03 0.05 0.05 0.01 0.04 2.0e-02 1.7e-02 1.5e-01 2.8e-02
17 BLA gene expression Ncln 0.27 0.14 5.6e-17 0.26 0.31 0.32 0.31 3.2e-14 5.0e-17 2.2e-17 4.4e-17
18 PL gene expression Ncln 0.44 0.16 0.0e+00 0.47 0.51 0.51 0.51 2.1e-58 6.1e-65 8.1e-65 5.2e-65
19 OFC gene expression Ncln 0.65 0.17 1.1e-16 0.48 0.46 0.47 0.48 3.3e-13 2.2e-12 1.4e-12 3.8e-13
20 PL mRNA stability Ncln 0.44 0.15 0.0e+00 0.5 0.49 0.5 0.5 1.1e-63 8.8e-62 7.4e-63 7.7e-63
21 Brain mRNA stability Ncln 0.63 0.17 0.0e+00 0.5 0.49 0.5 0.5 8.3e-53 1.1e-51 1.3e-52 1.4e-52
22 Liver gene expression Ncln 0.29 0.13 0.0e+00 0.17 0.18 0.17 0.17 1.7e-18 2.2e-19 1.5e-18 2.6e-18

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density1.01.77.9-1.31.31.31.2-1.2-1.2-1.2-1.41.21.0-0.81.51.1-0.41.00.2-0.20.9-1.61.61.62.8
Area under the delay curve1.51.62.31.2-1.2-1.2-1.21.21.31.21.1-1.3-1.31.3-1.1-1.21.5-1.2-1.51.5-1.41.2-1.2-1.20.4
BMI with tail6.119.822.94.6-4.6-4.6-4.54.64.64.64.4-4.6-4.74.7-4.4-4.64.8-4.6-4.84.8-4.54.3-4.3-4.3-1.1
BMI without tail2.75.67.22.4-2.4-2.4-2.42.42.42.52.4-2.4-2.42.4-2.4-2.72.4-2.4-2.32.3-2.32.4-2.4-2.4-1.3
Body weight1.25.25.92.4-2.4-2.4-2.42.42.32.32.3-2.3-2.42.4-2.3-2.22.4-2.3-2.32.4-2.42.3-2.3-2.3-0.7
Weight adjusted by age0.50.61.20.8-0.8-0.8-0.80.70.70.80.8-0.7-0.80.7-0.8-1.10.7-0.8-0.60.6-0.70.8-0.8-0.8-0.9
Bone surface2.84.917.1-2.22.22.22.2-2.1-2.2-2.2-2.52.21.9-1.72.62.2-1.11.90.9-0.91.6-2.52.52.54.1
Bone volume2.95.017.1-2.32.32.32.3-2.2-2.2-2.2-2.52.22.0-1.72.62.2-1.11.90.9-0.91.7-2.62.62.64.1
Breakpoint value in progressive ratio session3.74.16.0-1.91.91.91.9-1.9-2.1-1.9-1.82.12.1-2.11.72.0-2.32.12.4-2.42.2-2.02.02.0-0.4
Number of licking bursts0.40.52.10.8-0.8-0.8-0.80.80.80.70.9-0.8-0.60.6-0.9-0.60.4-0.7-0.30.3-0.20.3-0.3-0.3-1.4
Context. condit. distance diff. score0.40.50.90.7-0.7-0.7-0.70.70.60.70.7-0.6-0.70.7-0.7-0.60.7-0.7-0.70.6-0.80.9-0.9-0.9-0.3
Locomotion velocity, session 11.31.42.2-1.31.31.31.3-1.3-1.3-1.3-1.41.31.2-1.21.41.3-1.01.30.9-0.90.6-0.50.50.51.5
Locomotion distance, session 10.60.83.6-1.01.01.01.0-1.0-0.9-1.0-1.10.90.8-0.81.20.9-0.50.90.4-0.40.2-0.20.20.21.9
Locomotion velocity, session 25.36.27.7-2.72.72.72.7-2.7-2.6-2.7-2.72.62.6-2.52.82.7-2.32.62.2-2.22.1-2.12.12.12.2
Locomotion distance, session 22.63.75.2-2.22.22.22.1-2.1-2.0-2.1-2.22.02.0-1.92.32.1-1.72.01.6-1.61.3-1.31.31.32.2
Locomotion velocity, session 35.46.37.6-2.62.62.62.6-2.6-2.6-2.6-2.52.62.6-2.72.42.5-2.82.62.8-2.82.6-2.42.42.40.3
Locomotion distance, session 30.00.00.0-0.10.10.10.0-0.1-0.0-0.0-0.00.00.1-0.10.0-0.0-0.10.00.1-0.10.10.0-0.0-0.0-0.2
Stereotopy head waving bouts, day 35.05.96.4-2.52.52.52.5-2.5-2.5-2.5-2.52.52.5-2.52.42.5-2.52.52.5-2.52.4-2.42.42.41.1
Stereotopy head waving duration, day 35.46.47.1-2.62.62.62.6-2.6-2.6-2.6-2.62.62.6-2.72.52.6-2.72.62.7-2.72.5-2.42.42.40.9
Locomotion velocity, session 71.11.21.5-1.11.11.11.1-1.1-1.0-1.1-1.11.01.1-1.11.11.1-1.01.11.0-1.01.1-1.21.21.20.7
Locomotion distance, session 70.20.20.80.5-0.5-0.5-0.50.50.50.50.6-0.5-0.40.4-0.6-0.50.3-0.5-0.30.3-0.30.4-0.4-0.4-0.9
Stereotopy head waving bouts, day 70.30.32.0-0.50.50.50.5-0.5-0.6-0.6-0.60.60.4-0.30.70.6-0.20.50.1-0.10.0-0.10.10.11.4
Stereotopy head waving duration, day 70.70.82.8-1.01.01.01.0-0.9-1.0-1.0-1.11.00.8-0.71.11.0-0.60.90.5-0.50.5-0.70.70.71.7
Locomotion velocity, session 81.41.64.3-1.41.41.41.4-1.4-1.4-1.4-1.51.41.2-1.11.61.4-0.91.30.8-0.80.7-0.90.90.92.1
Locomotion distance, session 80.20.20.5-0.60.60.60.6-0.6-0.5-0.6-0.60.50.5-0.50.60.5-0.40.50.4-0.40.10.0-0.0-0.00.7
Degree of sensitization distance0.30.30.40.6-0.6-0.6-0.60.60.60.60.6-0.6-0.60.6-0.6-0.50.7-0.6-0.60.6-0.60.5-0.5-0.5-0.0
Degree of sensitization stereotypy0.91.01.80.9-0.9-0.9-0.90.90.90.90.7-0.9-1.01.1-0.7-0.81.2-1.0-1.31.3-1.31.1-1.1-1.10.9
Conditioned locomotion2.93.44.22.0-2.0-2.0-2.01.92.02.02.0-2.0-1.91.8-2.0-2.01.6-1.9-1.61.6-1.61.7-1.7-1.7-1.8
Cocaine response after cond. corrected7.48.39.82.9-2.9-2.9-2.92.92.92.93.0-3.0-2.92.8-3.0-2.92.7-2.9-2.62.6-2.93.1-3.1-3.1-2.0
Cocaine response after cond. not corrected8.18.910.13.1-3.1-3.1-3.13.13.13.13.1-3.1-3.02.9-3.1-3.02.8-3.0-2.72.7-3.03.2-3.2-3.2-2.1
Cocaine response before conditioning0.70.91.3-0.90.90.90.9-0.9-1.0-0.9-0.90.90.9-0.90.90.9-0.80.90.8-0.81.0-1.11.11.10.6
Saline control response0.10.10.30.3-0.3-0.3-0.30.30.50.30.3-0.4-0.30.3-0.3-0.40.3-0.4-0.30.3-0.40.5-0.5-0.5-0.5
Bone: connectivity density0.30.54.5-0.60.60.60.6-0.5-0.5-0.6-0.70.50.4-0.20.80.50.10.4-0.20.30.3-0.80.80.82.1
Bone: cortical apparent density1.11.51.91.2-1.2-1.2-1.31.21.11.21.2-1.1-1.21.3-1.2-1.11.2-1.2-1.21.2-1.41.4-1.4-1.4-0.3
Bone: cortical area0.10.22.10.3-0.3-0.3-0.20.30.10.20.1-0.1-0.40.5-0.1-0.20.7-0.3-0.80.7-0.4-0.20.20.21.5
Bone: cortical porosity0.91.01.3-1.01.01.01.0-1.0-1.0-1.0-1.01.00.9-0.91.01.0-0.91.00.8-0.81.0-1.11.11.10.8
Bone: cortical porosity0.30.41.5-0.60.60.60.6-0.6-0.6-0.6-0.60.60.5-0.40.70.6-0.30.50.2-0.20.5-0.70.70.71.2
Bone: cortical thickness0.71.11.81.1-1.1-1.1-1.11.11.01.11.0-1.0-1.11.2-0.9-1.01.4-1.1-1.41.3-1.10.8-0.8-0.80.5
Bone: cortical thickness0.10.10.70.2-0.2-0.2-0.20.20.30.30.3-0.3-0.20.1-0.3-0.30.0-0.2-0.0-0.0-0.10.2-0.2-0.2-0.9
Bone: cortical tissue density0.91.11.51.1-1.1-1.1-1.11.10.91.01.1-1.0-1.11.2-1.0-0.91.0-1.1-1.01.0-1.21.2-1.2-1.2-0.3
Condit. Reinf. active minus inactive responses3.94.45.1-2.22.22.22.2-2.2-2.1-2.2-2.12.12.2-2.22.12.2-2.22.22.2-2.22.1-1.91.91.90.5
Condit. Reinf. active-inactive response ratio1.41.52.3-1.21.21.21.2-1.2-1.2-1.2-1.11.21.3-1.41.11.3-1.51.31.5-1.51.4-1.21.21.2-0.4
Condit. Reinf. active responses4.35.35.9-2.42.42.42.4-2.4-2.4-2.4-2.42.42.4-2.42.42.4-2.22.42.2-2.22.2-2.22.22.21.4
Condit. Reinf. inactive responses1.61.92.5-1.51.51.51.5-1.4-1.4-1.4-1.51.41.4-1.31.61.4-1.11.41.1-1.11.2-1.41.41.41.6
Incentive salience index mean2.73.33.9-1.91.91.91.9-1.9-1.9-1.9-1.91.91.9-1.81.92.0-1.81.91.7-1.71.7-1.71.71.71.2
Condit. Reinf. lever presses0.60.84.2-0.90.90.90.9-0.9-0.9-0.9-1.00.90.7-0.61.11.0-0.40.80.3-0.30.5-0.80.80.82.1
Condit. Reinf. active minus inactive responses1.51.92.9-1.31.31.31.3-1.3-1.2-1.3-1.21.21.4-1.51.11.2-1.61.31.7-1.71.7-1.51.51.5-0.8
Condit. Reinf. active-inactive response ratio0.20.22.70.4-0.4-0.4-0.40.30.40.40.5-0.4-0.20.1-0.5-0.4-0.1-0.30.2-0.20.10.2-0.2-0.2-1.7
Condit. Reinf. active responses2.33.24.2-1.81.81.81.8-1.8-1.7-1.8-1.81.71.9-1.91.71.7-1.91.71.9-1.92.1-2.02.02.00.1
Condit. Reinf. inactive responses2.02.42.8-1.71.71.71.6-1.6-1.5-1.6-1.71.51.6-1.51.71.5-1.41.51.4-1.41.6-1.61.61.61.0
Condit. Reinf. lever presses1.82.43.3-1.51.51.51.5-1.6-1.4-1.5-1.41.41.6-1.71.41.4-1.81.51.8-1.81.8-1.61.61.6-0.5
Condit. Reinf. lever reinforcers received1.62.23.3-1.51.51.51.5-1.5-1.3-1.5-1.41.31.6-1.61.41.3-1.61.41.6-1.61.8-1.71.71.7-0.2
Conditioned reinforcement - actives2.92.93.2-1.71.71.71.7-1.7-1.8-1.7-1.71.81.7-1.81.71.6-1.71.71.7-1.81.8-1.71.71.70.5
Conditioned reinforcement - inactives1.51.72.31.4-1.4-1.4-1.41.41.31.41.5-1.4-1.31.2-1.5-1.01.0-1.3-0.91.0-1.21.4-1.4-1.4-1.3
Conditioned locomotion7.59.110.7-3.03.03.03.0-3.1-3.0-3.0-2.93.03.1-3.22.93.0-3.23.13.3-3.33.2-3.03.03.00.4
Patch foraging indifference point 0 sec0.10.20.30.4-0.4-0.4-0.40.40.50.40.4-0.5-0.50.5-0.4-0.20.5-0.4-0.50.5-0.50.4-0.4-0.40.2
Patch foraging indifference point AUC0.91.01.3-1.01.01.01.1-1.1-1.1-1.0-1.01.11.1-1.11.00.8-1.11.01.1-1.21.1-1.01.01.0-0.0
Delay disc. indifference point, 0s delay4.04.47.22.0-2.0-2.0-2.02.02.02.01.8-2.0-2.22.3-1.6-1.92.6-2.0-2.72.7-2.42.0-2.0-2.01.5
Delay disc. indifference point, 16s delay0.10.10.10.3-0.3-0.3-0.30.30.30.30.2-0.3-0.30.3-0.2-0.30.4-0.3-0.30.4-0.30.3-0.3-0.30.2
Delay disc. indifference point, 2s delay3.94.36.32.0-2.0-2.0-2.02.12.12.01.9-2.1-2.22.3-1.8-2.02.4-2.1-2.52.5-2.32.0-2.0-2.00.7
Delay disc. indifference point, 24s delay0.40.40.60.6-0.6-0.6-0.60.60.70.60.5-0.7-0.60.6-0.5-0.80.7-0.6-0.70.8-0.60.6-0.6-0.6-0.1
Delay disc. indifference point, 4s delay0.40.41.10.5-0.5-0.5-0.50.50.60.50.4-0.6-0.60.7-0.3-0.60.9-0.6-0.91.0-0.80.5-0.5-0.51.0
Delay disc. indifference point, 8s delay1.31.41.51.2-1.2-1.2-1.21.21.21.21.2-1.2-1.21.2-1.2-1.21.1-1.2-1.11.1-1.11.2-1.2-1.2-0.7
Indifference point function ln k0.30.40.50.7-0.7-0.7-0.70.70.70.70.7-0.7-0.70.7-0.7-0.50.7-0.7-0.60.6-0.70.6-0.6-0.6-0.2
Indifference point function log k0.30.40.50.7-0.7-0.7-0.70.70.70.70.7-0.7-0.70.7-0.7-0.50.7-0.7-0.60.6-0.70.6-0.6-0.6-0.2
Patch foraging total patch changes 0 sec0.10.20.30.5-0.5-0.5-0.50.50.50.40.4-0.5-0.50.5-0.4-0.20.5-0.5-0.50.5-0.40.4-0.4-0.4-0.0
Patch foraging total patch changes 12 sec0.60.71.10.8-0.8-0.8-0.80.81.00.90.9-1.0-0.80.8-0.9-1.10.8-0.9-0.70.7-0.70.8-0.8-0.8-1.0
Patch foraging total patch changes 18 sec0.91.11.4-1.11.11.11.1-1.1-1.1-1.1-1.11.11.1-1.11.01.1-1.11.11.2-1.21.1-1.11.11.10.1
Patch foraging total patch changes 24 sec0.20.20.4-0.60.60.60.6-0.6-0.4-0.5-0.60.40.5-0.50.60.2-0.40.40.4-0.40.4-0.40.40.40.3
Patch foraging total patch changes 6 sec0.10.20.4-0.40.40.40.4-0.4-0.3-0.4-0.40.30.4-0.40.40.7-0.40.40.5-0.50.4-0.30.30.30.0
Patch foraging time to switch 0 sec0.71.12.30.9-0.9-0.9-0.91.01.11.00.8-1.1-1.11.2-0.8-1.01.4-1.1-1.51.5-1.20.9-0.9-0.91.0
Patch foraging water rate 0 sec0.20.32.40.5-0.5-0.5-0.50.40.50.40.6-0.5-0.30.3-0.6-0.40.0-0.30.1-0.1-0.20.5-0.5-0.5-1.5
Patch foraging water rate 12 sec1.92.93.51.8-1.8-1.8-1.81.81.71.71.8-1.7-1.71.6-1.9-1.71.4-1.7-1.31.3-1.51.8-1.8-1.8-1.8
Patch foraging water rate 18 sec0.60.87.30.8-0.8-0.8-0.80.80.80.81.0-0.8-0.60.4-1.1-0.70.1-0.60.1-0.1-0.30.8-0.8-0.8-2.7
Patch foraging water rate 24 sec2.33.110.31.8-1.8-1.8-1.81.81.91.82.0-1.9-1.61.4-2.1-1.61.0-1.6-0.80.8-1.21.8-1.8-1.8-3.2
Patch foraging water rate 6 sec0.10.23.3-0.00.00.00.0-0.10.1-0.00.1-0.10.2-0.3-0.2-0.1-0.50.00.6-0.60.40.0-0.0-0.0-1.8
Seeking ratio, delayed vs. immediate footshock6.06.97.6-2.72.72.72.7-2.7-2.6-2.7-2.72.62.7-2.72.62.8-2.62.62.6-2.52.7-2.72.72.71.1
Distance traveled before self-admin0.10.10.20.2-0.2-0.2-0.20.20.30.30.2-0.3-0.30.3-0.2-0.40.4-0.3-0.40.4-0.40.3-0.3-0.30.4
Distance traveled after self-admin1.21.31.6-1.31.31.31.2-1.2-1.1-1.2-1.21.11.3-1.21.21.0-1.21.11.1-1.11.2-1.11.11.10.5
Extensor digitorum longus weight5.220.523.04.8-4.8-4.8-4.84.84.74.84.8-4.6-4.74.7-4.8-4.64.6-4.7-4.54.5-4.34.1-4.1-4.1-2.3
Bone: elastic displacement0.20.30.4-0.50.50.50.5-0.5-0.6-0.5-0.50.70.5-0.60.50.6-0.60.60.6-0.60.4-0.40.40.40.2
Bone: elastic work0.10.10.30.3-0.3-0.3-0.20.30.10.20.2-0.1-0.30.3-0.2-0.10.4-0.2-0.40.4-0.50.3-0.3-0.30.6
Bone: endosteal estimation0.10.10.60.3-0.3-0.3-0.30.30.20.30.2-0.2-0.40.4-0.2-0.20.6-0.3-0.60.6-0.50.2-0.2-0.20.8
Bone: endosteal perimeter0.61.32.2-1.11.11.11.1-1.1-1.2-1.1-1.11.31.0-1.01.21.2-0.81.10.8-0.81.0-1.31.31.31.5
Epididymis fat weight0.00.10.5-0.10.10.10.1-0.2-0.3-0.1-0.10.30.3-0.30.00.1-0.40.30.5-0.50.4-0.30.30.3-0.7
Delta time in closed arm before/after self-admin2.12.15.01.5-1.5-1.5-1.51.51.51.51.6-1.5-1.41.2-1.7-1.61.0-1.4-0.90.9-1.11.4-1.4-1.4-2.2
Delta time in open arm before/after self-admin1.11.01.41.0-1.0-1.0-1.01.01.01.01.0-1.0-1.11.2-0.9-0.91.1-1.0-1.21.1-1.11.0-1.0-1.00.1
Diff in mean of infusions in LGA sessions1.31.41.8-1.21.21.21.2-1.2-1.3-1.2-1.11.31.3-1.31.11.2-1.31.21.3-1.41.3-1.21.21.20.1
Delay discount exponential model param1.31.42.0-1.21.21.21.2-1.2-1.2-1.2-1.11.21.2-1.31.01.2-1.41.21.4-1.41.3-1.21.21.2-0.3
Extinction: sum of active levers before priming0.50.51.3-0.50.50.50.5-0.5-0.6-0.5-0.40.60.6-0.70.30.6-0.90.61.0-1.00.8-0.60.60.6-1.1
Active lever presses in extinction session 63.23.13.5-1.81.81.81.8-1.8-1.9-1.7-1.71.81.8-1.81.71.7-1.81.81.8-1.91.8-1.81.81.80.5
Bone: final force0.40.71.60.7-0.7-0.7-0.70.80.70.70.6-0.7-0.91.0-0.5-0.71.2-0.8-1.31.2-0.90.4-0.4-0.41.2
Bone: final moment0.30.51.30.7-0.7-0.7-0.60.70.60.70.6-0.6-0.80.9-0.5-0.61.1-0.7-1.11.1-0.80.3-0.3-0.31.1
Food consumed during 24 hour testing period0.40.50.60.6-0.6-0.6-0.70.60.80.70.6-0.8-0.70.8-0.6-0.80.7-0.8-0.80.8-0.70.8-0.8-0.8-0.2
Glucose1.21.72.11.3-1.3-1.3-1.31.31.41.31.3-1.4-1.31.3-1.2-1.41.4-1.4-1.41.4-1.41.4-1.4-1.4-0.5
Heart weight0.20.20.5-0.40.40.40.4-0.5-0.4-0.4-0.40.40.5-0.60.30.3-0.60.40.7-0.60.5-0.30.30.3-0.7
Delay discount hyperbolic model param2.02.13.0-1.41.41.41.4-1.4-1.5-1.4-1.31.51.5-1.51.31.4-1.71.41.7-1.71.6-1.41.41.4-0.3
Intermittent access intake day 1-15 change5.15.07.1-2.22.22.22.2-2.2-2.3-2.2-2.12.32.3-2.42.02.5-2.62.32.7-2.62.5-2.22.22.2-0.2
Intermittent access intake escalation3.43.46.1-1.71.71.71.7-1.7-1.8-1.7-1.51.71.8-2.01.42.0-2.31.92.5-2.42.1-1.71.71.7-1.2
Intermittent access intake escalation 24.84.77.7-2.12.12.12.1-2.1-2.1-2.1-1.92.12.3-2.41.82.2-2.72.22.8-2.82.5-2.12.12.1-1.1
Intermitt. access day 1 inactive lever presses0.10.10.8-0.20.20.20.2-0.2-0.2-0.2-0.10.20.4-0.40.10.3-0.60.30.6-0.60.5-0.30.30.3-0.9
Intermitt. access day 15 inactive lever presses0.10.10.4-0.20.20.20.2-0.2-0.3-0.3-0.10.30.3-0.40.10.5-0.60.30.6-0.60.4-0.20.20.2-0.6
Intermitt. access escalation Index0.20.11.9-0.20.20.20.2-0.2-0.3-0.2-0.30.30.10.00.40.10.20.1-0.30.3-0.1-0.20.20.21.4
Intermittent access day 1 total infusions0.10.10.10.3-0.3-0.3-0.30.30.10.30.3-0.2-0.30.3-0.3-0.10.3-0.3-0.30.3-0.40.3-0.3-0.30.1
Intermittent access day 15 total infusions0.91.01.8-0.80.80.80.9-0.9-1.1-0.9-0.71.01.0-1.00.71.2-1.31.01.3-1.31.1-0.90.90.9-0.7
Intermittent access terminal intake (last 3 days)0.91.01.4-0.90.90.91.0-1.0-1.2-1.0-0.91.11.0-1.00.91.0-1.11.01.1-1.11.0-1.01.01.00.0
Intermittent access total infusions0.00.00.2-0.10.10.10.1-0.1-0.3-0.1-0.00.20.1-0.20.00.4-0.30.20.3-0.30.2-0.10.10.1-0.4
Intermittent access day 1 locomotion0.10.10.3-0.10.10.10.2-0.2-0.4-0.2-0.10.30.3-0.30.10.5-0.40.30.5-0.40.3-0.20.20.2-0.4
Intermittent access day 15 total locomotion2.22.43.7-1.41.41.41.4-1.4-1.7-1.5-1.31.61.6-1.61.31.8-1.91.61.9-1.91.7-1.51.51.5-0.4
Intermittent access total locomotion0.70.81.3-0.80.80.80.9-0.8-1.1-0.9-0.81.00.9-0.90.81.2-1.10.91.1-1.10.9-0.90.90.9-0.0
Intermittent access standard deviation2.32.43.5-1.51.51.51.5-1.6-1.6-1.5-1.41.51.6-1.71.41.5-1.81.61.9-1.91.7-1.51.51.5-0.4
Left kidney weight0.20.61.6-0.80.80.80.8-0.8-0.8-0.8-0.90.80.7-0.71.00.7-0.40.70.4-0.40.6-0.80.80.81.3
Right kidney weight1.74.75.3-2.22.22.22.2-2.2-2.2-2.2-2.22.22.2-2.22.22.1-2.12.22.1-2.22.3-2.32.32.30.8
Cocaine induced anxiety1.72.02.5-1.51.51.51.5-1.5-1.4-1.4-1.51.41.4-1.31.61.2-1.11.41.1-1.11.3-1.51.51.51.4
Post-drug Anxiety1.71.93.5-1.51.51.51.5-1.4-1.4-1.4-1.61.41.3-1.31.61.0-0.81.30.8-0.91.2-1.51.51.51.9
Baseline Anxiety0.00.00.40.2-0.2-0.2-0.20.20.20.20.2-0.1-0.20.1-0.2-0.10.0-0.10.0-0.1-0.10.2-0.2-0.2-0.6
Tail length2.47.19.9-2.72.72.72.7-2.7-2.7-2.7-2.52.72.8-2.92.42.7-3.12.73.1-3.12.9-2.52.52.5-0.3
Length with tail1.76.48.1-2.62.62.62.6-2.6-2.6-2.7-2.52.62.7-2.62.52.8-2.82.62.7-2.72.5-2.32.32.30.7
Length without tail0.20.41.6-0.60.60.60.6-0.6-0.6-0.7-0.70.70.6-0.50.71.0-0.50.60.4-0.30.4-0.60.60.61.3
Times rat made contact with spout0.30.40.80.6-0.6-0.6-0.60.50.80.60.6-0.8-0.50.6-0.6-0.80.5-0.7-0.50.5-0.30.4-0.4-0.4-0.9
Lifetime Intake0.00.00.1-0.10.10.10.1-0.1-0.3-0.1-0.10.20.1-0.10.10.3-0.20.20.2-0.20.1-0.10.10.1-0.1
Liver weight, left2.84.45.42.2-2.2-2.2-2.22.22.22.22.2-2.1-2.22.2-2.2-2.32.2-2.2-2.12.1-2.01.9-1.9-1.9-1.0
Liver weight, right1.52.53.11.7-1.7-1.7-1.61.71.51.61.6-1.5-1.71.7-1.6-1.61.7-1.6-1.71.8-1.71.5-1.5-1.5-0.1
Locomotor activity4.57.18.8-2.72.72.72.7-2.7-2.7-2.8-2.72.72.7-2.62.73.0-2.52.72.5-2.52.7-2.82.82.81.7
Locomotor testing distance2.23.74.9-1.91.91.91.9-1.9-2.1-2.0-1.92.02.0-1.91.92.2-1.92.01.9-1.91.9-1.91.91.91.1
Locomotor testing rearing0.00.00.10.0-0.0-0.0-0.00.0-0.10.00.10.00.00.0-0.10.0-0.10.00.1-0.1-0.00.1-0.1-0.1-0.4
Locomotion in novel chamber0.40.50.7-0.70.70.70.7-0.7-0.5-0.6-0.70.60.7-0.80.70.3-0.70.60.7-0.80.8-0.70.70.7-0.3
Locomotion in novel chamber post-restriction0.70.81.0-0.90.90.90.9-0.9-1.0-0.9-0.90.90.9-0.90.90.9-0.90.91.0-1.01.0-1.01.01.00.2
Fecal boli incidents, locomotor time 12.52.73.51.6-1.6-1.6-1.61.61.71.61.6-1.7-1.61.7-1.7-1.71.5-1.8-1.61.5-1.61.9-1.9-1.9-1.3
Change in fecal boli incidents, locomotor task1.00.92.1-0.90.90.90.9-0.9-1.1-1.0-1.01.00.9-0.81.11.0-0.71.00.7-0.70.8-1.11.11.11.5
Time >=10cm from walls, locomotor time 10.10.10.90.1-0.1-0.1-0.10.10.20.10.0-0.1-0.20.40.0-0.10.4-0.2-0.50.4-0.40.3-0.3-0.30.9
Bouts of movement, locomotor time 10.10.10.2-0.40.40.40.4-0.4-0.4-0.4-0.30.30.4-0.30.30.3-0.50.30.4-0.40.3-0.20.20.2-0.2
Total resting periods, locomotor time 10.20.20.4-0.50.50.50.5-0.6-0.6-0.6-0.50.50.6-0.50.50.5-0.60.50.5-0.50.5-0.40.40.40.1
Rest time, locomotor task time 10.20.30.3-0.60.60.60.6-0.6-0.6-0.6-0.60.50.5-0.40.60.5-0.50.50.4-0.50.4-0.40.40.40.4
Distance moved, locomotor task time 10.10.11.10.2-0.2-0.2-0.20.20.20.20.1-0.2-0.30.3-0.1-0.10.5-0.2-0.50.6-0.30.0-0.0-0.01.0
Vertical activity count, locomotor time 10.10.10.20.3-0.3-0.3-0.30.30.40.30.3-0.4-0.20.2-0.3-0.30.2-0.3-0.20.2-0.20.2-0.2-0.2-0.4
Time >=10cm from walls, locomotor time 21.51.61.91.4-1.4-1.4-1.41.41.31.41.4-1.3-1.31.3-1.4-1.21.3-1.2-1.11.1-1.21.2-1.2-1.2-0.8
Bouts of movement, locomotor time 20.90.91.5-1.01.01.01.0-1.0-1.0-1.0-1.11.01.0-0.81.11.0-0.81.00.7-0.70.8-0.90.90.91.2
Total resting periods, locomotor time 20.91.01.8-1.11.11.11.1-1.0-1.0-1.0-1.11.01.0-0.81.21.0-0.81.00.7-0.70.8-0.90.90.91.3
Rest time, locomotor task time 20.91.01.3-1.11.11.11.1-1.1-1.1-1.1-1.11.11.0-0.91.11.0-0.91.00.8-0.80.9-1.01.01.00.9
Distance moved, locomotor task time 21.31.51.91.4-1.4-1.4-1.41.31.31.31.4-1.3-1.31.2-1.4-1.11.1-1.2-1.01.1-1.11.2-1.2-1.2-1.0
Vertical activity count, locomotor time 21.71.92.41.5-1.5-1.5-1.51.41.41.41.5-1.4-1.41.3-1.6-1.31.1-1.3-1.01.0-1.21.4-1.4-1.4-1.5
Light reinforcement 15.710.412.0-3.43.43.43.3-3.4-3.1-3.4-3.33.13.4-3.43.23.5-3.43.33.4-3.33.3-3.13.13.10.8
Light reinforcement 21.72.33.0-1.51.51.51.5-1.5-1.5-1.6-1.51.51.5-1.51.51.7-1.61.51.6-1.61.6-1.51.51.50.4
Bone: marrow area0.10.20.60.4-0.4-0.4-0.30.40.20.30.3-0.2-0.40.5-0.3-0.20.6-0.4-0.60.6-0.50.2-0.2-0.20.8
Bone: maximum diameter1.42.53.7-1.51.51.51.5-1.5-1.7-1.6-1.61.71.5-1.41.61.7-1.21.61.2-1.21.5-1.91.91.91.8
Bone: maximum force0.61.01.91.0-1.0-1.0-1.01.00.91.00.9-0.9-1.11.2-0.8-0.91.4-1.0-1.41.4-1.10.6-0.6-0.60.9
Bone: maximum moment0.50.81.60.9-0.9-0.9-0.91.00.80.90.8-0.8-1.01.1-0.8-0.81.3-0.9-1.31.2-1.00.6-0.6-0.60.9
Mean time between licks in bursts2.84.05.8-2.02.02.02.0-2.0-2.1-2.0-1.92.12.1-2.21.82.1-2.32.02.4-2.42.1-1.81.81.8-0.3
Mean num. licks in bursts0.00.00.3-0.30.30.30.3-0.2-0.1-0.2-0.30.10.1-0.20.30.0-0.00.2-0.00.1-0.10.2-0.2-0.20.6
Cd content in liver0.10.10.20.3-0.3-0.3-0.30.40.30.30.3-0.3-0.40.4-0.3-0.30.4-0.4-0.40.4-0.30.1-0.1-0.10.1
Co content in liver0.40.40.9-0.50.50.50.5-0.5-0.5-0.5-0.40.50.6-0.60.40.6-0.70.60.8-0.80.9-0.90.90.9-0.4
Cu content in liver0.10.11.4-0.30.30.30.3-0.3-0.2-0.3-0.40.20.2-0.10.40.30.10.2-0.10.10.1-0.30.30.31.2
Fe content in liver0.00.10.50.2-0.2-0.2-0.20.20.20.20.3-0.2-0.20.1-0.3-0.20.0-0.20.0-0.0-0.00.1-0.1-0.1-0.7
K content in liver0.20.21.5-0.50.50.50.5-0.5-0.5-0.5-0.60.50.4-0.30.60.5-0.20.50.2-0.10.1-0.30.30.31.2
Mg content in liver0.40.42.2-0.60.60.60.6-0.6-0.7-0.6-0.70.60.5-0.40.70.6-0.20.60.2-0.20.3-0.50.50.51.5
Mn content in liver3.03.37.5-1.91.91.91.9-1.9-2.0-1.9-2.12.01.7-1.72.11.9-1.31.91.2-1.21.3-1.61.61.62.7
Na content in liver0.50.61.00.7-0.7-0.7-0.70.70.70.70.6-0.7-0.80.8-0.6-0.70.9-0.7-1.01.0-0.90.8-0.8-0.80.7
Rb content in liver0.10.12.00.1-0.1-0.1-0.10.1-0.10.0-0.10.0-0.20.30.1-0.00.4-0.1-0.50.5-0.40.1-0.1-0.11.4
Se content in liver0.30.30.4-0.60.60.60.6-0.6-0.5-0.6-0.60.50.6-0.60.60.5-0.50.60.5-0.50.5-0.40.40.40.3
Sr content in liver0.30.21.70.5-0.5-0.5-0.50.40.50.50.6-0.5-0.40.3-0.6-0.50.1-0.4-0.10.1-0.20.4-0.4-0.4-1.3
Zn content in liver0.70.82.9-0.60.60.60.6-0.7-0.7-0.6-0.50.60.8-1.00.40.6-1.20.81.4-1.41.1-0.70.70.7-1.7
Bone: minimum diameter0.10.21.4-0.30.30.30.3-0.3-0.4-0.3-0.40.40.2-0.20.40.4-0.00.3-0.0-0.00.2-0.50.50.51.2
Time in familiar zone, hab. session 11.61.52.0-1.21.21.21.2-1.2-1.2-1.2-1.11.21.3-1.31.11.2-1.41.21.4-1.41.3-1.11.11.1-0.2
Time in novel zone, hab. session 10.30.31.20.4-0.4-0.4-0.50.50.50.40.3-0.5-0.50.7-0.3-0.40.8-0.5-0.90.9-0.50.1-0.1-0.11.1
Total zone transitions, hab. session 11.62.23.0-1.61.61.61.6-1.6-1.6-1.6-1.71.61.5-1.51.71.5-1.31.61.2-1.21.2-1.21.21.21.7
Total locomotion distance, hab. session 12.63.76.9-2.12.12.12.1-2.0-2.0-2.0-2.22.01.9-1.82.22.0-1.52.01.4-1.31.5-1.71.71.72.6
Locomotion velocity, hab. session 12.73.95.0-2.12.12.12.1-2.1-2.1-2.1-2.22.12.0-1.92.22.0-1.72.01.6-1.61.6-1.81.81.82.2
Time in familiar zone, hab. session 24.44.66.5-2.12.12.12.1-2.1-2.1-2.1-2.02.12.2-2.31.92.1-2.52.12.6-2.52.5-2.12.12.1-0.7
Time in novel zone, hab. session 22.82.84.41.6-1.6-1.6-1.61.61.61.61.5-1.6-1.71.8-1.4-1.62.1-1.7-2.12.1-2.01.6-1.6-1.60.9
Total zone transitions, hab. session 20.20.33.4-0.40.40.40.4-0.3-0.2-0.4-0.50.20.2-0.10.60.30.20.3-0.30.3-0.60.5-0.5-0.51.8
Total locomotion distance, hab. session 21.41.82.6-1.51.51.51.6-1.5-1.4-1.5-1.61.41.4-1.41.61.4-1.21.51.1-1.10.8-0.70.70.71.5
Locomotion velocity, hab. session 21.52.13.5-1.61.61.61.7-1.6-1.5-1.6-1.71.51.5-1.51.81.5-1.21.51.1-1.10.9-0.80.80.81.9
Novel to familiar place preference ratio2.12.13.61.3-1.3-1.3-1.31.41.31.31.2-1.3-1.51.6-1.1-1.31.8-1.4-1.91.9-1.81.5-1.5-1.51.2
Novelty place preference1.11.12.00.9-0.9-0.9-0.90.90.90.90.7-0.9-1.01.1-0.7-0.91.3-0.9-1.41.4-1.41.1-1.1-1.11.2
Time in novel zone, NPP test1.31.42.41.0-1.0-1.0-1.01.11.01.00.9-1.0-1.21.3-0.8-1.01.5-1.1-1.51.5-1.51.2-1.2-1.21.1
Total zone transitions, NPP test0.10.10.9-0.30.30.30.3-0.3-0.2-0.3-0.40.20.2-0.20.40.2-0.00.3-0.00.0-0.30.4-0.4-0.41.0
Total locomotion distance, NPP test0.10.21.9-0.40.40.40.5-0.4-0.3-0.4-0.50.30.3-0.30.60.3-0.00.4-0.00.1-0.20.1-0.1-0.11.4
Locomotion velocity, NPP test0.30.41.9-0.70.70.70.7-0.7-0.6-0.7-0.80.60.6-0.60.80.6-0.30.60.3-0.20.1-0.10.10.11.4
Intraocular pressure0.10.22.40.3-0.3-0.3-0.30.20.40.30.4-0.4-0.20.1-0.4-0.6-0.0-0.30.0-0.1-0.10.4-0.4-0.4-1.5
Delta distance traveled before/after self-admin1.61.72.0-1.41.41.41.4-1.4-1.3-1.4-1.31.21.4-1.41.31.4-1.41.31.4-1.41.4-1.31.31.30.3
Delta ambulatory time before/after self-admin2.22.42.7-1.61.61.61.6-1.6-1.6-1.6-1.61.51.6-1.61.61.5-1.51.51.5-1.51.5-1.51.51.50.7
Parametrial fat weight0.30.60.9-0.60.60.60.6-0.6-0.7-0.7-0.60.80.8-0.80.50.8-0.90.70.9-0.90.9-0.90.90.9-0.3
Pavlov. Cond. lever latency0.20.21.90.5-0.5-0.5-0.50.40.50.50.5-0.5-0.40.3-0.6-0.50.1-0.4-0.00.0-0.20.4-0.4-0.4-1.4
Pavlov. Cond. magazine entry latency2.02.63.6-1.71.71.71.7-1.7-1.7-1.7-1.61.71.7-1.81.51.7-1.81.71.9-1.91.7-1.41.41.4-0.0
Pavlov. Cond. change in total contacts0.10.10.1-0.30.30.30.3-0.3-0.3-0.3-0.30.30.3-0.30.30.3-0.30.30.3-0.30.1-0.00.00.00.2
Pavlov. Cond. index score0.60.81.0-0.90.90.91.0-0.9-0.9-0.9-1.00.90.9-0.91.01.0-0.80.90.7-0.70.7-0.70.70.71.0
Pavlov. Cond. latency score0.81.01.8-1.11.11.11.1-1.0-1.1-1.1-1.11.11.0-0.91.21.1-0.81.00.7-0.70.7-0.80.80.81.3
Pavlov. Cond. lever contacts0.50.62.7-0.80.80.80.8-0.8-0.8-0.8-0.90.80.7-0.61.00.8-0.40.70.3-0.30.5-0.80.80.81.7
Pavlov. Cond. magazine entry number0.50.60.80.8-0.8-0.8-0.80.80.80.80.8-0.8-0.80.9-0.8-0.80.9-0.8-0.90.9-0.70.6-0.6-0.6-0.2
Pavlov. Cond. intertrial magazine entries0.10.11.00.1-0.1-0.1-0.10.10.20.10.2-0.1-0.0-0.0-0.2-0.2-0.1-0.10.2-0.20.2-0.00.00.0-1.0
Pavlov. Cond. lever-magazine prob. diff.1.01.21.5-1.21.21.21.2-1.2-1.2-1.2-1.21.21.1-1.11.21.2-1.01.21.0-1.00.9-0.90.90.90.9
Pavlov. Cond. response bias1.01.21.3-1.11.11.11.1-1.1-1.1-1.1-1.11.11.1-1.21.11.1-1.21.11.2-1.21.1-1.01.01.00.3
Pavlov. Cond. lever latency1.11.41.71.2-1.2-1.2-1.21.21.21.21.2-1.2-1.21.2-1.2-1.11.2-1.2-1.21.2-1.31.3-1.3-1.3-0.4
Pavlov. Cond. magazine entry latency0.80.91.3-0.90.90.90.9-0.9-1.0-0.9-0.91.00.9-0.80.91.0-0.90.90.8-0.91.0-1.21.21.20.6
Pavlov. Cond. change in total contacts0.91.31.7-1.11.11.11.1-1.2-1.1-1.1-1.11.11.2-1.21.11.0-1.21.11.2-1.21.3-1.31.31.30.1
Pavlov. Cond. index score1.11.41.9-1.21.21.21.1-1.2-1.2-1.2-1.11.21.2-1.21.11.1-1.21.21.2-1.21.3-1.41.41.40.3
Pavlov. Cond. latency score1.21.42.1-1.21.21.21.2-1.2-1.2-1.2-1.21.21.2-1.11.21.2-1.21.21.1-1.21.3-1.41.41.40.5
Pavlov. Cond. lever contacts0.71.01.3-1.01.01.01.0-1.0-1.0-1.0-0.91.01.0-1.00.90.9-1.11.01.1-1.11.1-1.01.01.0-0.1
Pavlov. Cond. magazine entry number1.21.51.91.2-1.2-1.2-1.21.21.31.21.2-1.3-1.21.2-1.2-1.31.2-1.2-1.11.2-1.31.4-1.4-1.4-0.7
Pavlov. Cond. intertrial magazine entries0.91.22.01.0-1.0-1.0-1.01.01.21.01.0-1.2-1.01.0-1.1-0.90.9-1.0-0.80.8-1.21.4-1.4-1.4-1.0
Pavlov. Cond. lever-magazine prob. diff.1.21.52.0-1.21.21.21.2-1.2-1.3-1.2-1.21.31.3-1.21.21.2-1.21.21.2-1.21.4-1.41.41.40.5
Pavlov. Cond. response bias1.72.32.9-1.51.51.51.5-1.5-1.5-1.5-1.41.51.6-1.61.41.4-1.71.51.7-1.71.7-1.61.61.6-0.0
Time in closed arm before self-admin0.30.31.10.4-0.4-0.4-0.50.50.50.40.3-0.5-0.50.6-0.3-0.30.8-0.5-0.90.9-0.70.5-0.5-0.51.0
Time in closed arm after self-admin0.00.00.1-0.20.20.20.2-0.20.0-0.2-0.20.00.2-0.20.2-0.1-0.10.10.1-0.10.2-0.10.10.1-0.1
Time in open arm before self-admin0.90.91.3-1.01.01.01.0-1.0-0.9-0.9-0.90.91.0-1.10.90.9-1.11.01.2-1.11.1-1.01.01.0-0.2
Time in open arm after self-admin1.01.11.41.2-1.2-1.2-1.21.21.01.11.2-1.0-1.11.1-1.2-0.81.0-1.0-0.91.0-1.11.0-1.0-1.0-0.5
Bone: periosteal estimation0.10.22.60.2-0.2-0.2-0.10.20.00.10.0-0.0-0.30.40.0-0.00.6-0.2-0.70.6-0.4-0.20.20.21.6
Bone: periosteal perimeter0.50.83.1-0.80.80.80.8-0.8-1.0-0.8-0.91.00.7-0.61.01.0-0.40.80.4-0.40.7-1.21.21.21.8
Bone: post-yield work0.60.81.00.9-0.9-0.9-0.90.90.90.90.9-0.9-0.91.0-0.9-0.91.0-1.0-1.00.9-0.80.7-0.7-0.7-0.2
Progressive ratio test 1 active lever presses0.40.40.50.7-0.7-0.7-0.70.70.50.70.7-0.6-0.60.6-0.7-0.50.4-0.6-0.40.4-0.60.7-0.7-0.7-0.6
Progressive ratio test 1 breakpoint0.40.40.50.7-0.7-0.7-0.70.70.50.70.7-0.6-0.60.6-0.7-0.60.5-0.6-0.50.5-0.60.7-0.7-0.7-0.5
Progressive ratio test 1 inactive lever presses0.00.00.00.0-0.0-0.0-0.00.0-0.10.00.00.00.00.0-0.00.1-0.00.00.0-0.0-0.0-0.00.00.00.0
Progressive ratio test 2 active lever presses0.10.10.3-0.20.20.20.2-0.2-0.3-0.2-0.10.30.2-0.30.10.2-0.40.30.4-0.50.3-0.20.20.2-0.5
Progressive ratio test 2 breakpoint0.30.30.5-0.50.50.50.6-0.5-0.7-0.5-0.50.60.5-0.60.50.5-0.60.60.6-0.60.6-0.60.60.60.0
Progressive ratio test 2 inactive lever presses0.10.10.1-0.20.20.20.2-0.2-0.4-0.2-0.20.30.2-0.20.20.3-0.20.30.2-0.20.2-0.20.20.20.2
Incentive Sensitization - Responses0.20.20.4-0.40.40.40.4-0.4-0.5-0.3-0.30.40.4-0.50.30.2-0.50.40.6-0.60.5-0.40.40.4-0.5
Incentive Sensitization - Breakpoint0.30.30.5-0.60.60.60.6-0.6-0.6-0.5-0.50.60.6-0.60.50.3-0.60.60.7-0.70.7-0.60.60.6-0.2
Sum of active levers in priming session hrs 5-60.00.00.10.2-0.2-0.2-0.20.20.10.20.2-0.1-0.20.1-0.2-0.10.1-0.1-0.00.0-0.10.1-0.1-0.1-0.3
Progressive ratio0.30.30.70.5-0.5-0.5-0.50.50.50.60.5-0.5-0.50.4-0.6-0.90.5-0.6-0.50.5-0.40.5-0.5-0.5-0.7
Food seeking constrained by brief footshock0.10.10.2-0.40.40.40.4-0.4-0.3-0.3-0.30.30.4-0.40.30.2-0.30.40.4-0.30.5-0.50.50.50.1
Seeking ratio, punishment vs. effort0.10.10.4-0.30.30.30.3-0.3-0.3-0.4-0.30.30.4-0.30.30.6-0.40.40.4-0.30.3-0.40.40.40.4
Retroperitoneal fat weight0.82.63.31.7-1.7-1.7-1.71.71.61.61.7-1.6-1.61.6-1.7-1.21.4-1.6-1.31.3-1.71.8-1.8-1.8-1.0
Reaction time number correct1.21.72.31.4-1.4-1.4-1.41.31.41.41.4-1.4-1.31.2-1.4-1.41.1-1.3-1.01.0-1.21.4-1.4-1.4-1.5
Reaction time mean minus median0.81.11.5-1.01.01.01.0-1.0-1.2-1.0-1.01.21.0-1.01.01.0-1.01.11.1-1.11.0-1.01.01.00.4
Reaction time mean minus median AUC0.40.53.0-0.70.70.70.7-0.7-0.9-0.7-0.80.90.6-0.50.90.7-0.30.70.2-0.30.2-0.50.50.51.7
Reaction time num false alarms0.10.10.30.2-0.2-0.2-0.20.20.30.20.2-0.3-0.20.2-0.2-0.40.2-0.3-0.20.2-0.20.4-0.4-0.4-0.5
Reaction time num false alarms AUC0.20.30.90.5-0.5-0.5-0.50.50.60.60.5-0.6-0.50.4-0.6-0.70.4-0.6-0.40.3-0.50.7-0.7-0.7-0.9
Reaction time trials correct on left1.21.72.31.4-1.4-1.4-1.41.31.41.41.4-1.4-1.31.2-1.4-1.41.1-1.3-1.01.0-1.21.4-1.4-1.4-1.5
Reaction time trials on left1.21.62.01.3-1.3-1.3-1.31.31.31.31.4-1.3-1.31.2-1.4-1.31.1-1.2-1.01.0-1.11.3-1.3-1.3-1.4
Reaction time mean0.10.21.6-0.40.40.40.4-0.3-0.6-0.4-0.50.60.3-0.20.50.4-0.00.40.1-0.10.1-0.40.40.41.3
Reaction time mean AUC0.10.11.5-0.20.20.20.3-0.2-0.5-0.3-0.30.40.2-0.10.40.40.10.3-0.00.00.0-0.30.30.31.2
Median of all reaction times0.10.11.40.2-0.2-0.2-0.10.2-0.00.10.1-0.0-0.20.3-0.0-0.10.5-0.1-0.50.5-0.40.1-0.1-0.11.2
Reaction time omissions0.30.40.6-0.70.70.70.7-0.7-0.7-0.7-0.70.70.6-0.60.70.7-0.60.70.6-0.70.5-0.50.50.50.5
Reaction time false alarm rate0.00.00.0-0.20.20.20.1-0.2-0.1-0.1-0.20.10.1-0.10.2-0.0-0.00.0-0.0-0.0-0.00.1-0.1-0.10.2
Reaction time premature initiation rate0.30.41.1-0.50.50.50.5-0.6-0.5-0.6-0.40.60.7-0.80.40.8-0.90.71.0-1.00.7-0.40.40.4-0.9
Reaction time premature initiations0.20.23.10.1-0.1-0.1-0.10.10.10.10.3-0.10.1-0.2-0.30.1-0.50.00.6-0.60.20.3-0.3-0.3-1.8
Std. dev. reaction times0.40.61.0-0.80.80.80.8-0.8-1.0-0.8-0.81.00.7-0.70.90.8-0.60.80.6-0.70.5-0.60.60.60.9
Reaction time trials completed1.21.62.01.3-1.3-1.3-1.31.31.31.31.4-1.3-1.31.2-1.4-1.31.1-1.2-1.01.0-1.11.3-1.3-1.3-1.4
Reaction time trials AUC1.21.82.81.4-1.4-1.4-1.41.41.41.41.4-1.4-1.31.2-1.5-1.41.0-1.3-0.90.9-1.21.4-1.4-1.4-1.7
Run reversals in cocaine runway, females1.41.41.8-1.31.31.31.3-1.3-1.1-1.2-1.31.01.2-1.31.30.8-1.01.10.9-0.91.2-1.31.31.31.0
Run reversals in cocaine runway, males1.91.82.3-1.41.41.41.4-1.4-1.4-1.3-1.41.41.4-1.41.41.1-1.21.41.2-1.21.4-1.51.51.50.9
Latency to leave start box in cocaine runway2.12.32.9-1.61.61.61.6-1.6-1.6-1.6-1.71.51.5-1.31.71.7-1.21.51.1-1.21.3-1.51.51.51.6
Latency to leave start box in cocaine runway, F0.80.84.7-0.90.90.90.9-0.9-1.0-0.9-1.10.80.7-0.51.10.9-0.30.80.2-0.30.4-0.90.90.92.2
Latency to leave start box in cocaine runway, M1.71.62.8-1.21.21.21.2-1.3-1.2-1.2-1.11.21.3-1.41.01.2-1.61.21.6-1.71.4-1.11.11.1-0.9
Std. dev. time between licks in bursts1.41.72.1-1.31.31.31.3-1.3-1.3-1.3-1.41.31.3-1.21.41.4-1.11.31.1-1.11.2-1.41.41.41.3
Total sessions with >9 infusions0.20.21.0-0.40.40.40.5-0.4-0.6-0.4-0.50.60.4-0.30.60.3-0.20.40.1-0.20.3-0.50.50.51.0
Short access day 1 total inactive lever presses0.00.00.0-0.10.10.10.1-0.1-0.2-0.1-0.10.10.1-0.10.10.1-0.20.10.2-0.20.1-0.10.10.1-0.1
Short access day 10 total inactive lever presses0.10.10.70.2-0.2-0.2-0.20.20.20.10.3-0.2-0.10.0-0.3-0.0-0.2-0.10.2-0.10.00.2-0.2-0.2-0.8
Short access day 1 total infusions0.40.51.2-0.70.70.70.7-0.7-0.9-0.6-0.70.80.6-0.50.80.6-0.40.60.4-0.40.5-0.70.70.71.1
Short access day 10 total infusions0.00.00.10.0-0.0-0.0-0.00.0-0.20.00.00.1-0.00.0-0.0-0.00.00.00.0-0.1-0.00.0-0.0-0.0-0.1
Short access total infusions0.10.10.4-0.30.30.30.3-0.3-0.5-0.2-0.30.40.2-0.20.30.1-0.10.20.0-0.10.1-0.30.30.30.6
Short access day 1 locomotion0.90.91.9-0.90.90.90.9-0.9-1.1-1.0-0.91.10.9-0.90.91.4-1.01.01.0-0.90.9-0.90.90.90.7
Short access day 10 total locomotion2.83.14.7-1.71.71.71.7-1.7-1.8-1.7-1.51.71.8-1.91.52.0-2.11.82.2-2.12.0-1.71.71.7-0.4
Short access total locomotion0.90.91.4-0.90.90.90.9-0.9-1.2-1.0-0.91.11.0-0.90.91.1-1.11.01.0-1.00.9-1.01.01.00.4
One hour access (0.3 mA shock)0.30.40.50.7-0.7-0.7-0.70.70.50.70.7-0.6-0.70.7-0.7-0.40.6-0.6-0.50.6-0.70.7-0.7-0.7-0.3
Compulsive drug intake0.60.60.90.7-0.7-0.7-0.70.80.90.70.7-0.8-0.80.8-0.7-0.71.0-0.8-0.91.0-0.80.7-0.7-0.70.3
One hour access (shock baseline)0.10.10.60.3-0.3-0.3-0.30.30.10.30.3-0.2-0.20.2-0.40.0-0.0-0.20.1-0.1-0.10.3-0.3-0.3-0.8
Social response proportion0.80.91.1-1.01.01.01.0-1.0-1.1-1.0-1.01.11.0-1.01.00.8-0.91.00.9-0.90.9-0.90.90.90.7
Social responses8.911.513.2-3.53.53.53.5-3.5-3.6-3.5-3.53.63.5-3.53.53.4-3.43.53.3-3.33.3-3.33.33.31.7
Social time1.11.42.01.2-1.2-1.2-1.21.21.11.21.2-1.1-1.21.2-1.2-1.01.1-1.1-1.01.1-1.31.4-1.4-1.4-0.6
Soleus weight8.123.928.45.1-5.1-5.1-5.15.14.95.04.9-4.9-5.15.2-4.8-5.05.3-5.1-5.35.3-5.04.5-4.5-4.5-0.9
Bone: stiffness1.82.84.81.7-1.7-1.7-1.71.71.81.71.6-1.8-1.81.9-1.5-1.82.1-1.8-2.22.2-1.61.1-1.1-1.10.5
Tibialis anterior weight0.72.63.51.7-1.7-1.7-1.71.71.71.71.7-1.6-1.71.8-1.6-1.71.8-1.7-1.91.9-1.41.0-1.0-1.0-0.2
Time to tail flick, vehicle, before self-admin1.71.72.5-1.41.41.41.4-1.4-1.4-1.3-1.51.31.3-1.21.51.2-1.01.30.9-0.91.1-1.31.31.31.6
Time to tail flick, vehicle, after self-admin0.10.11.00.1-0.1-0.1-0.00.00.20.10.1-0.20.0-0.1-0.2-0.4-0.1-0.10.2-0.20.10.1-0.1-0.1-1.0
Time to tail flick, test, before self-admin0.80.82.4-0.90.90.90.9-0.9-1.0-0.9-1.01.00.8-0.81.00.7-0.50.90.5-0.50.6-0.90.90.91.5
Time to tail flick, test, after self-admin0.60.60.8-0.80.80.80.8-0.8-0.9-0.8-0.90.80.8-0.70.90.6-0.60.70.5-0.50.6-0.70.70.70.9
Delta time to tail flick, vehicle, before/after SA1.61.63.21.3-1.3-1.3-1.31.31.41.31.4-1.3-1.21.1-1.5-1.40.9-1.2-0.80.9-1.01.3-1.3-1.3-1.8
Delta time to tail flick, test, before/after SA0.10.10.90.1-0.1-0.1-0.10.10.10.10.2-0.2-0.0-0.0-0.2-0.0-0.2-0.10.2-0.20.10.1-0.1-0.1-1.0
Tibia length0.72.02.6-1.31.31.31.4-1.4-1.4-1.4-1.31.41.5-1.51.21.5-1.61.41.6-1.61.6-1.51.51.5-0.1
Ambulatory time before self-admin0.10.10.20.3-0.3-0.3-0.30.30.30.30.3-0.3-0.30.4-0.3-0.40.4-0.4-0.40.4-0.40.4-0.4-0.40.1
Ambulatory time after self-admin0.60.70.9-0.90.90.90.9-0.9-0.8-0.9-0.90.80.9-0.80.90.7-0.90.80.8-0.90.9-0.80.80.80.4
Bone: tissue strength1.71.62.41.3-1.3-1.3-1.31.31.11.21.2-1.1-1.31.4-1.2-1.11.4-1.2-1.41.3-1.51.4-1.4-1.40.2
Total heroin consumption2.02.42.9-1.61.61.61.6-1.6-1.7-1.5-1.61.71.6-1.61.51.4-1.61.61.6-1.61.6-1.61.61.60.5
Bone: trabecular number2.13.34.5-1.91.91.91.9-1.9-1.8-1.9-2.01.81.8-1.72.01.8-1.41.71.2-1.21.7-2.12.12.12.1
Bone: trabecular spacing2.33.07.61.8-1.8-1.8-1.81.71.71.81.9-1.7-1.61.4-2.0-1.71.1-1.6-0.90.9-1.52.0-2.0-2.0-2.8
Bone: trabecular thickness2.32.813.3-1.61.61.61.6-1.5-1.6-1.6-1.81.61.3-1.11.91.6-0.61.40.4-0.41.1-1.91.91.93.6
Bone: trabecular tissue density3.54.95.72.4-2.4-2.4-2.42.32.22.32.4-2.2-2.32.3-2.4-2.22.1-2.2-2.01.9-2.22.2-2.2-2.2-1.6
Water consumed over 24 hours0.10.11.10.1-0.1-0.1-0.20.20.30.20.0-0.3-0.30.4-0.0-0.30.6-0.3-0.70.7-0.2-0.10.10.11.1
Number of responses in last shaping day0.20.20.3-0.40.40.40.4-0.4-0.5-0.4-0.40.50.5-0.40.40.5-0.40.40.4-0.40.4-0.40.40.40.2