Hub : Genes

Myrf

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver intron excision ratio chr1_206860518_206861185 0.14 0.06 4.4e-15 0.1 0.1 0.1 0.1 5.3e-11 7.4e-11 1.3e-11 7.3e-11
2 Liver isoform ratio XM_008760222.3 0.09 0.07 1.4e-04 0.03 0.02 0.02 0.02 1.6e-04 2.3e-03 1.8e-03 1.1e-03
3 Liver intron excision ratio chr1_206860769_206861185 0.13 0.07 6.1e-10 0.07 0.06 0.05 0.06 5.7e-08 6.4e-07 1.8e-06 1.4e-07
4 Liver intron excision ratio chr1_206860521_206860689 0.1 0.05 4.0e-10 0.05 0.06 0.04 0.05 4.3e-06 5.4e-07 1.8e-05 5.4e-06
5 Brain gene expression Myrf 0.1 0.06 1.1e-08 0.09 0.06 0.08 0.04 1.3e-08 5.3e-06 1.0e-07 1.3e-04
6 Eye intron excision ratio chr1_206860769_206861185 0.46 0.17 3.4e-03 0.09 0.06 0.1 0.07 1.8e-02 4.4e-02 1.4e-02 2.9e-02
7 Liver isoform ratio XM_006231030.4 0.24 0.09 0.0e+00 0.12 0.12 0.12 0.12 2.4e-13 6.1e-13 2.5e-13 1.1e-12
8 Liver intron excision ratio chr1_206860518_206860689 0.09 0.05 9.6e-05 0.03 0.02 0.02 0.02 2.6e-04 1.4e-03 3.3e-03 1.1e-03
9 Liver intron excision ratio chr1_206860521_206861185 0.12 0.07 2.0e-07 0.05 0.05 0.05 0.04 1.1e-06 2.0e-06 1.1e-06 9.3e-06
10 Adipose mRNA stability Myrf 0.03 0.02 2.1e-03 0.03 0.02 0.01 0.02 7.0e-04 5.3e-03 1.9e-02 1.8e-03
11 Liver isoform ratio XM_008760220.3 0.07 0.04 1.8e-07 0.02 0.05 0.07 0.04 1.8e-03 3.0e-06 2.1e-08 1.7e-05
12 Liver isoform ratio XM_006231031.4 0.08 0.04 2.0e-06 0.04 0.04 0.05 0.05 1.1e-05 9.2e-06 7.3e-06 4.4e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.30.51.60.4-0.7-0.60.6-0.6-1.2-0.6-0.60.6-0.90.1-0.8
Area under the delay curve0.60.62.00.7-1.4-0.50.8-0.6-1.3-0.4-0.40.4-1.00.4-0.5
BMI with tail0.72.210.9-0.8-0.6-1.20.3-1.2-1.5-1.2-1.21.2-0.4-2.1-3.3
BMI without tail0.10.31.2-1.00.10.1-0.60.10.20.10.1-0.10.5-0.7-1.1
Body weight0.41.58.4-1.3-0.30.8-1.00.7-0.80.70.7-0.70.1-2.0-2.9
Weight adjusted by age1.41.65.4-2.31.70.5-1.30.60.80.40.4-0.41.6-2.1-1.2
Bone surface0.30.63.70.2-0.6-0.10.3-0.2-1.9-0.2-0.20.2-0.9-0.3-1.4
Bone volume0.50.83.60.5-0.8-0.50.7-0.6-1.9-0.6-0.60.6-1.30.0-1.3
Breakpoint value in progressive ratio session3.43.75.3-2.32.22.1-2.12.11.72.02.0-2.02.0-1.50.0
Number of licking bursts0.10.20.60.3-0.8-0.10.4-0.1-0.4-0.1-0.10.1-0.7-0.4-0.6
Context. condit. distance diff. score0.20.20.40.3-0.5-0.60.4-0.50.2-0.5-0.50.5-0.30.4-0.3
Locomotion velocity, session 10.40.41.6-0.61.2-0.2-0.5-0.20.9-0.2-0.20.21.3-0.20.5
Locomotion distance, session 10.40.51.4-1.21.1-0.2-0.7-0.10.7-0.1-0.10.11.2-1.10.1
Locomotion velocity, session 20.60.72.4-1.30.70.6-0.90.60.20.60.6-0.60.6-1.6-1.1
Locomotion distance, session 20.50.71.7-1.11.00.3-1.00.41.10.40.4-0.41.3-1.30.1
Locomotion velocity, session 31.31.64.40.7-1.3-1.31.1-1.2-1.0-1.2-1.21.2-1.4-0.1-2.1
Locomotion distance, session 30.30.31.10.9-0.7-0.40.5-0.3-0.2-0.3-0.30.3-0.71.1-0.1
Stereotopy head waving bouts, day 30.81.01.50.7-1.0-1.21.0-1.2-0.6-1.2-1.21.2-0.8-0.3-1.0
Stereotopy head waving duration, day 30.40.51.10.4-1.0-0.70.6-0.6-0.3-0.6-0.60.6-0.7-0.3-1.0
Locomotion velocity, session 70.40.41.20.8-1.0-0.40.7-0.3-0.5-0.3-0.30.3-1.1-0.2-0.8
Locomotion distance, session 70.20.31.00.7-1.0-0.60.6-0.5-0.1-0.5-0.50.5-0.50.1-0.4
Stereotopy head waving bouts, day 70.10.10.6-0.20.0-0.10.0-0.0-0.2-0.0-0.00.00.0-0.4-0.8
Stereotopy head waving duration, day 70.40.41.0-0.70.20.7-0.70.7-0.40.70.7-0.70.3-0.6-1.0
Locomotion velocity, session 80.30.30.6-0.10.20.6-0.60.70.80.70.7-0.70.40.10.6
Locomotion distance, session 80.20.30.80.2-0.3-0.90.5-0.7-0.0-0.7-0.70.7-0.1-0.0-0.5
Degree of sensitization distance0.70.71.9-0.1-0.4-1.00.6-0.9-0.2-0.9-0.90.9-0.1-1.4-1.1
Degree of sensitization stereotypy0.30.30.7-0.80.50.5-0.60.6-0.20.60.6-0.60.4-0.5-0.8
Conditioned locomotion0.40.41.5-0.80.20.5-0.60.60.60.60.6-0.60.5-1.2-0.2
Cocaine response after cond. corrected0.30.30.8-0.20.4-0.80.1-0.70.9-0.7-0.70.70.4-0.40.6
Cocaine response after cond. not corrected0.40.40.9-0.20.6-0.90.3-0.90.3-0.9-0.90.90.4-0.30.4
Cocaine response before conditioning0.20.21.2-0.30.90.2-0.10.0-1.10.10.1-0.10.2-0.1-0.4
Saline control response1.51.93.7-1.91.41.4-1.61.30.91.31.3-1.31.3-1.80.1
Bone: connectivity density0.10.21.2-0.3-0.2-0.1-0.0-0.1-0.9-0.1-0.10.1-0.4-0.5-1.1
Bone: cortical apparent density0.81.01.4-1.20.91.2-1.11.10.91.11.1-1.10.8-0.70.2
Bone: cortical area0.10.11.0-0.20.20.2-0.10.1-1.00.10.1-0.1-0.20.0-0.6
Bone: cortical porosity0.50.60.9-0.40.50.9-0.70.91.00.90.9-0.90.6-0.40.7
Bone: cortical porosity1.11.21.8-0.70.81.3-1.11.21.31.21.2-1.21.0-0.70.9
Bone: cortical thickness2.54.05.8-2.12.02.4-2.42.31.42.32.3-2.31.8-1.30.7
Bone: cortical thickness0.70.81.2-0.70.71.1-1.01.10.91.11.1-1.10.50.10.5
Bone: cortical tissue density1.01.31.7-1.31.01.3-1.21.31.01.31.3-1.30.9-0.80.2
Condit. Reinf. active minus inactive responses1.01.23.4-1.71.90.2-1.10.30.80.30.3-0.31.7-1.50.0
Condit. Reinf. active-inactive response ratio2.22.45.8-2.12.40.7-1.60.81.50.80.8-0.82.3-1.90.9
Condit. Reinf. active responses0.50.61.8-1.31.3-0.3-0.5-0.30.2-0.3-0.30.31.0-1.3-0.8
Condit. Reinf. inactive responses1.01.22.00.6-0.7-1.41.0-1.2-0.9-1.2-1.21.2-0.90.7-1.4
Incentive salience index mean0.30.41.1-1.01.1-0.2-0.4-0.30.1-0.3-0.30.30.9-0.9-0.6
Condit. Reinf. lever presses0.40.51.20.4-0.5-0.70.6-0.8-1.0-0.8-0.80.8-0.70.3-1.1
Condit. Reinf. active minus inactive responses0.20.20.9-0.70.9-0.30.1-0.40.3-0.4-0.40.40.4-0.70.3
Condit. Reinf. active-inactive response ratio0.60.61.4-0.0-0.3-0.90.9-1.0-0.3-1.0-1.01.0-0.7-0.5-1.2
Condit. Reinf. active responses0.10.20.8-0.70.9-0.1-0.2-0.20.1-0.2-0.20.20.4-0.80.2
Condit. Reinf. inactive responses0.20.21.4-0.10.80.2-0.40.1-0.10.10.1-0.10.60.21.2
Condit. Reinf. lever presses0.30.41.4-0.80.4-0.1-0.1-0.1-1.1-0.1-0.10.1-0.0-1.2-1.2
Condit. Reinf. lever reinforcers received0.30.41.5-1.11.20.2-0.50.10.30.10.1-0.10.7-1.10.1
Conditioned reinforcement - actives0.40.40.80.20.4-0.90.5-0.80.3-0.8-0.80.8-0.10.60.8
Conditioned reinforcement - inactives1.21.32.10.8-0.7-1.41.2-1.4-0.9-1.5-1.51.5-1.10.5-0.6
Conditioned locomotion1.92.33.81.7-1.4-1.81.8-1.9-1.1-1.6-1.61.6-1.61.2-0.3
Patch foraging indifference point 0 sec0.20.40.6-0.70.20.7-0.50.70.30.70.7-0.70.2-0.8-0.3
Patch foraging indifference point AUC1.11.33.8-1.41.31.2-1.11.10.31.11.1-1.10.8-2.0-0.4
Delay disc. indifference point, 0s delay1.41.62.41.2-1.4-1.51.3-1.5-1.3-1.3-1.31.3-1.30.0-0.8
Delay disc. indifference point, 16s delay0.30.31.4-0.1-0.7-0.60.5-0.5-1.2-0.5-0.50.5-0.5-0.1-0.7
Delay disc. indifference point, 2s delay1.71.93.61.2-1.6-1.41.5-1.4-1.9-1.4-1.41.4-1.40.7-0.8
Delay disc. indifference point, 24s delay0.10.10.60.3-0.80.00.2-0.1-0.70.10.1-0.1-0.30.2-0.1
Delay disc. indifference point, 4s delay0.60.73.10.8-1.8-0.30.7-0.3-0.9-0.3-0.30.3-1.20.5-0.7
Delay disc. indifference point, 8s delay0.40.42.51.0-1.6-0.10.7-0.1-0.60.00.0-0.0-0.90.60.1
Indifference point function ln k3.04.26.62.2-1.8-2.62.2-2.5-0.7-2.5-2.52.5-1.81.4-0.1
Indifference point function log k3.04.26.62.2-1.8-2.62.2-2.5-0.7-2.5-2.52.5-1.81.4-0.1
Patch foraging total patch changes 0 sec0.30.60.9-0.80.40.9-0.70.90.71.01.0-1.00.3-0.60.1
Patch foraging total patch changes 12 sec4.25.57.7-2.71.82.8-2.62.71.32.72.7-2.71.7-2.5-0.5
Patch foraging total patch changes 18 sec0.81.01.6-1.11.21.2-1.01.00.61.01.0-1.01.1-1.30.4
Patch foraging total patch changes 24 sec2.12.66.8-1.80.71.8-1.61.70.51.71.7-1.70.6-2.6-1.7
Patch foraging total patch changes 6 sec0.30.40.6-0.6-0.10.8-0.40.6-0.20.70.7-0.7-0.4-0.8-0.8
Patch foraging time to switch 0 sec0.30.52.20.1-0.5-0.50.4-0.6-1.5-0.5-0.50.5-0.5-0.1-1.4
Patch foraging water rate 0 sec0.20.31.30.50.10.00.10.10.7-0.0-0.00.0-0.11.21.1
Patch foraging water rate 12 sec0.60.92.31.0-0.9-1.00.9-0.90.6-1.0-1.01.0-0.51.50.8
Patch foraging water rate 18 sec0.71.03.21.4-1.2-1.00.9-0.9-0.0-0.9-0.90.9-0.81.80.4
Patch foraging water rate 24 sec0.60.84.01.2-0.8-0.80.7-0.60.5-0.6-0.60.6-0.52.00.7
Patch foraging water rate 6 sec0.40.62.20.9-0.9-0.50.6-0.40.7-0.5-0.50.5-0.31.51.0
Seeking ratio, delayed vs. immediate footshock0.20.30.60.5-0.7-0.50.5-0.4-0.6-0.4-0.40.4-0.8-0.5-0.6
Distance traveled before self-admin0.70.71.8-1.31.00.8-0.90.7-0.21.01.0-1.00.5-0.6-0.7
Distance traveled after self-admin0.10.10.3-0.40.30.6-0.20.1-0.50.20.2-0.2-0.0-0.3-0.2
Extensor digitorum longus weight1.45.515.9-3.31.32.1-2.62.00.72.02.0-2.01.3-4.0-2.9
Bone: elastic displacement0.91.03.9-0.30.90.6-0.70.62.00.60.6-0.61.10.51.9
Bone: elastic work1.41.93.0-1.41.31.3-1.61.41.71.41.4-1.41.5-0.61.2
Bone: endosteal estimation3.88.310.22.9-2.9-3.23.2-3.1-3.2-3.1-3.13.1-2.81.8-1.9
Bone: endosteal perimeter5.210.714.13.2-3.3-3.43.7-3.5-3.8-3.4-3.43.4-3.42.1-2.2
Epididymis fat weight1.84.16.62.3-2.6-2.02.3-2.0-1.8-2.0-2.02.0-2.31.2-1.6
Delta time in closed arm before/after self-admin1.41.32.7-1.50.70.9-1.41.01.50.90.9-0.91.3-1.6-0.2
Delta time in open arm before/after self-admin1.01.01.5-1.11.20.9-1.01.00.11.21.2-1.20.9-0.7-0.7
Diff in mean of infusions in LGA sessions3.53.95.2-1.72.32.0-2.12.31.72.22.2-2.21.9-1.70.2
Delay discount exponential model param0.60.62.1-0.71.50.5-0.80.61.30.40.4-0.41.0-0.50.5
Extinction: sum of active levers before priming1.31.32.5-1.60.81.0-1.41.40.61.21.2-1.21.1-1.1-0.9
Active lever presses in extinction session 61.91.93.1-1.81.61.6-1.71.40.91.41.4-1.41.5-0.7-0.2
Bone: final force0.20.30.9-0.90.50.2-0.60.2-0.60.30.3-0.30.3-0.8-0.9
Bone: final moment0.20.30.8-0.90.50.3-0.60.2-0.50.30.3-0.30.3-0.7-0.9
Food consumed during 24 hour testing period0.20.21.50.20.4-0.20.1-0.20.1-0.2-0.20.2-0.01.20.8
Glucose2.63.95.62.0-1.8-2.32.4-2.4-1.9-2.3-2.32.3-1.60.90.0
Heart weight0.81.12.31.5-1.5-1.11.2-1.1-0.7-1.1-1.11.1-0.90.7-0.0
Delay discount hyperbolic model param0.70.82.3-0.81.50.6-0.90.71.40.50.5-0.51.1-0.50.6
Intermittent access intake day 1-15 change0.30.31.40.20.7-0.10.0-0.00.50.10.1-0.10.20.91.2
Intermittent access intake escalation0.20.20.8-0.10.8-0.0-0.1-0.00.60.10.1-0.10.40.60.9
Intermittent access intake escalation 20.40.41.2-0.81.10.6-0.60.60.70.50.5-0.50.50.10.5
Intermitt. access day 1 inactive lever presses2.83.14.51.6-1.5-1.91.9-2.1-2.0-2.0-2.02.0-1.60.6-0.9
Intermitt. access day 15 inactive lever presses2.62.84.61.1-1.4-1.81.6-1.9-2.2-1.8-1.81.8-1.7-0.2-1.9
Intermitt. access escalation Index1.81.62.81.3-1.7-1.41.2-1.0-1.5-1.5-1.51.5-1.20.5-0.3
Intermittent access day 1 total infusions5.76.69.72.2-2.6-3.12.6-2.9-2.5-2.9-2.92.9-2.70.3-2.0
Intermittent access day 15 total infusions3.74.17.42.1-1.6-2.72.2-2.4-1.4-2.4-2.42.4-2.01.2-0.4
Intermittent access terminal intake (last 3 days)2.22.45.31.1-1.0-2.31.5-1.8-1.3-1.9-1.91.9-1.50.3-1.1
Intermittent access total infusions3.23.55.81.5-1.6-2.41.9-2.2-1.8-2.2-2.22.2-1.90.3-1.2
Intermittent access day 1 locomotion4.44.65.91.7-2.4-2.42.1-2.4-2.4-2.3-2.32.3-2.20.1-2.1
Intermittent access day 15 total locomotion1.71.83.10.8-1.1-1.61.3-1.8-1.4-1.4-1.41.4-1.3-0.2-1.7
Intermittent access total locomotion5.56.39.11.7-2.3-2.82.5-3.0-3.0-2.7-2.72.7-2.60.0-2.7
Intermittent access standard deviation0.80.94.1-0.81.50.1-0.60.22.00.40.4-0.41.20.11.1
Left kidney weight0.61.84.11.7-2.0-0.71.3-0.8-1.9-0.8-0.80.8-1.90.2-1.5
Right kidney weight0.31.02.21.0-1.2-0.60.9-0.7-1.5-0.7-0.70.7-1.4-0.1-1.4
Cocaine induced anxiety0.30.31.0-1.01.00.0-0.60.30.20.10.1-0.10.8-0.6-0.2
Post-drug Anxiety0.40.51.7-1.21.30.2-0.80.30.40.10.1-0.11.0-0.8-0.3
Baseline Anxiety0.60.61.2-0.90.71.1-0.80.60.90.90.9-0.90.7-0.7-0.3
Tail length0.92.84.7-1.30.82.2-1.92.11.42.22.2-2.21.3-0.30.5
Length with tail0.41.62.7-0.9-0.21.6-1.31.6-0.11.61.6-1.60.1-1.0-1.5
Length without tail0.20.52.4-0.1-0.40.4-0.20.4-0.90.40.4-0.4-0.4-1.1-1.6
Times rat made contact with spout0.80.91.4-0.91.00.9-1.10.91.10.90.9-0.91.2-0.70.9
Lifetime Intake2.52.95.11.4-1.5-2.31.7-2.1-1.3-2.0-2.02.0-1.60.3-1.1
Liver weight, left0.20.31.20.9-0.5-0.30.5-0.3-0.2-0.3-0.30.3-0.21.10.8
Liver weight, right0.20.40.80.30.2-0.90.4-0.9-0.3-0.9-0.90.90.20.20.3
Locomotor activity0.20.42.80.40.10.10.00.00.40.10.1-0.10.80.81.7
Locomotor testing distance0.20.42.20.50.1-0.30.2-0.40.4-0.3-0.30.30.90.71.5
Locomotor testing rearing0.30.41.90.20.6-0.50.2-0.60.4-0.5-0.50.50.90.51.4
Locomotion in novel chamber2.83.55.51.8-1.5-2.42.0-2.0-1.8-2.1-2.12.1-1.71.9-0.3
Locomotion in novel chamber post-restriction0.20.31.60.5-0.0-0.40.3-0.10.9-0.2-0.20.20.20.61.2
Fecal boli incidents, locomotor time 10.50.53.5-0.61.3-0.40.1-0.1-0.3-0.4-0.40.40.1-1.9-0.2
Change in fecal boli incidents, locomotor task2.01.94.81.8-2.1-1.11.3-1.4-0.9-1.1-1.11.1-1.12.20.3
Time >=10cm from walls, locomotor time 12.62.64.01.2-1.1-2.01.8-1.9-1.7-2.0-2.02.0-1.40.3-1.0
Bouts of movement, locomotor time 14.85.39.5-2.13.12.3-2.32.32.32.32.3-2.32.2-2.50.9
Total resting periods, locomotor time 13.03.36.6-1.62.61.8-1.81.81.51.91.9-1.91.7-2.00.5
Rest time, locomotor task time 10.20.20.70.80.0-0.20.5-0.10.0-0.2-0.20.2-0.5-0.70.5
Distance moved, locomotor task time 10.30.41.7-0.1-0.8-0.50.2-0.6-0.3-0.6-0.60.6-0.11.3-0.6
Vertical activity count, locomotor time 11.01.06.10.8-1.3-0.70.7-0.7-0.2-0.8-0.80.8-0.42.50.5
Time >=10cm from walls, locomotor time 20.10.10.4-0.10.20.00.10.1-0.60.10.1-0.10.30.50.2
Bouts of movement, locomotor time 23.74.010.0-2.92.71.3-2.01.42.11.31.3-1.32.3-3.2-0.2
Total resting periods, locomotor time 23.33.611.3-2.82.61.0-1.81.12.01.01.0-1.02.2-3.4-0.2
Rest time, locomotor task time 20.60.71.30.6-0.4-1.20.9-0.90.4-1.1-1.11.1-0.5-0.60.4
Distance moved, locomotor task time 20.50.61.4-0.30.21.0-0.70.90.10.90.9-0.90.61.20.4
Vertical activity count, locomotor time 21.11.23.60.0-0.01.2-0.81.10.71.11.1-1.10.91.91.6
Light reinforcement 10.10.10.70.20.70.1-0.0-0.2-0.10.00.0-0.00.40.40.8
Light reinforcement 21.31.84.61.2-1.2-1.11.5-1.2-2.1-1.1-1.11.1-1.70.7-1.1
Bone: marrow area4.08.610.53.0-3.0-3.23.2-3.1-3.2-3.1-3.13.1-2.92.0-1.8
Bone: maximum diameter0.61.03.80.6-1.0-0.60.9-0.8-2.0-0.8-0.80.8-1.20.3-1.5
Bone: maximum force0.50.94.6-0.3-0.5-0.50.2-0.5-2.0-0.4-0.40.4-0.8-0.6-2.1
Bone: maximum moment0.40.73.8-0.3-0.4-0.40.2-0.4-1.8-0.4-0.40.4-0.6-0.6-2.0
Mean time between licks in bursts0.81.12.8-1.41.00.7-1.20.71.70.70.7-0.71.3-1.60.4
Mean num. licks in bursts0.81.02.5-0.81.40.6-1.10.61.40.60.6-0.61.6-0.01.4
Cd content in liver0.50.51.70.30.2-0.80.6-0.8-0.1-0.9-0.90.90.10.71.3
Co content in liver0.60.85.20.20.60.4-0.40.41.10.40.4-0.40.70.92.3
Cu content in liver0.20.20.60.0-0.20.8-0.50.60.10.70.7-0.70.1-0.20.1
Fe content in liver0.00.00.1-0.0-0.10.0-0.0-0.10.1-0.1-0.10.1-0.10.2-0.3
K content in liver0.60.62.50.1-0.8-0.40.6-0.5-0.9-0.5-0.50.5-0.9-0.5-1.6
Mg content in liver0.70.81.30.2-0.3-1.10.7-1.1-0.8-1.1-1.11.1-0.4-0.6-1.1
Mn content in liver0.30.41.1-0.6-0.10.7-0.50.7-0.10.60.6-0.6-0.3-1.1-0.8
Na content in liver0.10.10.7-0.40.9-0.0-0.3-0.0-0.2-0.0-0.00.00.5-0.5-0.1
Rb content in liver1.21.52.41.5-1.0-1.41.4-1.5-0.6-1.4-1.41.4-1.01.30.2
Se content in liver0.30.31.6-0.0-0.40.00.10.1-0.6-0.0-0.00.0-0.6-1.2-1.3
Sr content in liver4.13.86.4-2.51.91.8-2.41.91.61.81.8-1.82.1-2.3-0.1
Zn content in liver2.12.35.8-2.41.91.1-1.71.11.31.01.0-1.01.7-2.0-0.8
Bone: minimum diameter3.26.18.82.5-2.2-2.62.6-2.7-3.0-2.6-2.62.6-2.31.5-1.8
Time in familiar zone, hab. session 10.10.10.3-0.10.2-0.40.1-0.3-0.5-0.3-0.30.3-0.0-0.5-0.4
Time in novel zone, hab. session 10.30.31.50.7-0.2-0.50.4-0.30.2-0.3-0.30.3-0.11.21.0
Total zone transitions, hab. session 10.60.81.2-0.90.90.8-1.00.91.00.90.9-0.91.1-0.50.7
Total locomotion distance, hab. session 10.20.30.6-0.2-0.1-0.80.4-0.8-0.2-0.8-0.80.80.1-0.4-0.3
Locomotion velocity, hab. session 10.10.20.6-0.80.4-0.1-0.3-0.10.4-0.1-0.10.10.6-0.8-0.2
Time in familiar zone, hab. session 20.10.11.00.30.4-0.00.00.00.10.00.0-0.00.30.21.0
Time in novel zone, hab. session 20.10.10.5-0.4-0.0-0.1-0.2-0.1-0.1-0.1-0.10.10.10.1-0.7
Total zone transitions, hab. session 20.40.61.8-0.91.30.2-0.90.30.80.30.3-0.31.4-0.60.4
Total locomotion distance, hab. session 20.30.41.0-0.60.7-0.6-0.1-0.60.1-0.6-0.60.60.7-1.00.0
Locomotion velocity, hab. session 20.30.40.7-0.30.4-0.80.2-0.8-0.1-0.8-0.80.80.4-0.8-0.2
Novel to familiar place preference ratio0.50.51.2-0.5-0.60.8-0.50.8-0.30.80.8-0.8-0.3-0.0-1.1
Novelty place preference0.40.41.3-0.3-0.80.7-0.30.7-0.50.70.7-0.7-0.50.0-1.1
Time in novel zone, NPP test0.40.41.4-0.5-0.50.6-0.40.7-0.40.70.7-0.7-0.2-0.3-1.2
Total zone transitions, NPP test1.11.63.1-1.41.60.9-1.51.11.31.11.1-1.11.8-1.10.7
Total locomotion distance, NPP test0.10.10.7-0.30.6-0.0-0.40.00.40.00.0-0.00.8-0.40.5
Locomotion velocity, NPP test0.10.10.5-0.00.40.2-0.40.20.30.20.2-0.20.6-0.00.7
Intraocular pressure0.40.51.2-0.60.80.6-0.60.60.90.60.6-0.60.7-1.10.6
Delta distance traveled before/after self-admin0.20.20.60.8-0.4-0.30.4-0.40.2-0.6-0.60.6-0.10.30.6
Delta ambulatory time before/after self-admin0.20.20.90.4-0.1-0.20.3-0.20.5-0.5-0.50.50.10.10.9
Parametrial fat weight4.07.712.43.0-3.2-2.63.2-2.7-3.5-2.6-2.62.6-3.41.1-1.8
Pavlov. Cond. lever latency0.10.10.60.2-0.10.3-0.00.30.80.30.3-0.30.10.30.5
Pavlov. Cond. magazine entry latency0.20.31.4-0.40.2-0.30.1-0.3-0.8-0.3-0.30.3-0.2-0.9-1.2
Pavlov. Cond. change in total contacts0.10.10.3-0.40.5-0.20.0-0.2-0.5-0.2-0.20.20.2-0.5-0.3
Pavlov. Cond. index score0.10.10.3-0.40.50.0-0.2-0.0-0.4-0.0-0.00.00.1-0.5-0.2
Pavlov. Cond. latency score0.10.10.3-0.10.3-0.30.1-0.3-0.5-0.3-0.30.3-0.1-0.2-0.2
Pavlov. Cond. lever contacts0.10.20.60.3-0.1-0.40.3-0.5-0.8-0.5-0.50.5-0.30.2-0.2
Pavlov. Cond. magazine entry number0.30.30.80.8-0.9-0.50.6-0.50.0-0.5-0.50.5-0.40.80.2
Pavlov. Cond. intertrial magazine entries0.60.81.4-0.71.10.9-0.90.90.60.90.9-0.91.0-0.11.2
Pavlov. Cond. lever-magazine prob. diff.0.10.10.5-0.60.60.2-0.30.1-0.40.10.1-0.10.3-0.7-0.3
Pavlov. Cond. response bias0.10.10.3-0.50.50.1-0.20.1-0.60.10.1-0.10.1-0.6-0.5
Pavlov. Cond. lever latency0.50.72.50.5-0.20.6-0.30.71.40.70.7-0.70.31.01.6
Pavlov. Cond. magazine entry latency1.92.26.4-2.51.91.1-1.71.0-0.11.01.0-1.01.3-2.1-1.6
Pavlov. Cond. change in total contacts0.50.72.2-1.51.30.0-0.5-0.0-0.8-0.0-0.00.00.6-1.2-1.5
Pavlov. Cond. index score1.01.24.4-1.81.20.3-0.80.2-1.10.20.2-0.20.4-1.8-2.1
Pavlov. Cond. latency score0.91.14.8-1.71.00.1-0.6-0.0-1.20.00.0-0.00.2-1.7-2.2
Pavlov. Cond. lever contacts0.50.72.5-1.41.3-0.0-0.5-0.1-0.4-0.1-0.10.10.8-1.6-0.8
Pavlov. Cond. magazine entry number2.63.18.72.9-2.0-1.42.0-1.30.1-1.3-1.31.3-1.42.32.2
Pavlov. Cond. intertrial magazine entries0.40.51.51.2-0.5-0.40.8-0.5-0.2-0.5-0.50.5-0.30.71.2
Pavlov. Cond. lever-magazine prob. diff.1.11.44.2-2.01.40.4-0.90.3-1.00.30.3-0.30.6-2.0-2.0
Pavlov. Cond. response bias0.81.03.1-1.81.50.3-0.90.2-0.50.30.3-0.30.9-1.8-1.3
Time in closed arm before self-admin0.40.41.70.6-0.2-0.50.7-0.5-1.3-0.5-0.50.5-0.90.4-0.5
Time in closed arm after self-admin0.20.20.50.3-0.3-0.70.4-0.4-0.0-0.6-0.60.6-0.4-0.00.2
Time in open arm before self-admin0.50.52.20.5-0.80.10.1-0.01.2-0.2-0.20.20.31.21.5
Time in open arm after self-admin1.21.42.2-0.60.71.5-1.11.21.31.51.5-1.51.10.21.0
Bone: periosteal estimation1.73.57.61.7-1.8-1.81.9-1.8-2.8-1.8-1.81.8-2.01.0-1.8
Bone: periosteal perimeter0.81.33.20.8-0.7-1.11.1-1.3-1.8-1.2-1.21.2-1.00.6-1.0
Bone: post-yield work5.27.011.72.4-2.6-2.72.9-2.7-3.4-2.6-2.62.6-2.91.5-2.5
Progressive ratio test 1 active lever presses0.91.02.21.5-0.9-1.21.1-1.1-0.6-0.9-0.90.9-1.11.00.2
Progressive ratio test 1 breakpoint0.80.82.01.4-0.7-1.11.0-0.9-0.4-0.7-0.70.7-0.91.10.4
Progressive ratio test 1 inactive lever presses0.40.51.60.3-0.8-0.70.5-0.7-0.7-0.6-0.60.6-0.6-0.4-1.3
Progressive ratio test 2 active lever presses2.02.23.51.6-1.2-1.91.6-1.8-1.3-1.6-1.61.6-1.51.1-0.4
Progressive ratio test 2 breakpoint2.12.33.51.9-1.3-1.81.7-1.7-1.3-1.6-1.61.6-1.61.40.0
Progressive ratio test 2 inactive lever presses2.42.84.41.3-1.3-2.11.7-2.0-1.5-2.0-2.02.0-1.70.3-1.3
Incentive Sensitization - Responses0.50.51.30.6-0.5-0.80.7-0.7-1.1-0.6-0.60.6-0.90.3-0.8
Incentive Sensitization - Breakpoint0.90.92.10.8-0.8-1.10.9-1.0-1.4-0.9-0.90.9-1.20.4-0.9
Sum of active levers in priming session hrs 5-61.21.22.1-1.31.41.2-1.31.30.81.01.0-1.01.2-0.70.1
Progressive ratio0.30.40.70.3-0.7-0.80.6-0.6-0.2-0.8-0.80.8-0.30.3-0.7
Food seeking constrained by brief footshock0.10.20.60.20.1-0.1-0.1-0.10.7-0.1-0.10.10.60.70.8
Seeking ratio, punishment vs. effort0.20.30.9-0.10.40.5-0.50.30.50.50.5-0.50.6-0.00.9
Retroperitoneal fat weight3.611.820.74.6-4.4-3.24.1-3.2-3.1-3.2-3.23.2-4.02.6-1.0
Reaction time number correct0.30.51.3-0.81.10.6-0.90.60.60.50.5-0.50.9-0.30.7
Reaction time mean minus median0.91.22.0-1.31.41.1-1.11.10.61.11.1-1.11.1-1.00.1
Reaction time mean minus median AUC1.92.44.3-1.72.11.5-1.61.51.41.61.6-1.61.8-1.31.0
Reaction time num false alarms0.30.41.60.3-0.20.7-0.40.60.80.70.7-0.70.30.71.3
Reaction time num false alarms AUC0.91.22.0-0.20.11.4-1.01.31.11.41.4-1.40.70.41.4
Reaction time trials correct on left0.30.51.3-0.81.10.6-0.90.60.60.50.5-0.50.9-0.30.7
Reaction time trials on left0.40.61.5-0.91.20.7-1.00.70.70.60.6-0.61.0-0.30.8
Reaction time mean0.30.51.9-0.91.40.2-0.60.30.60.30.3-0.31.2-0.60.2
Reaction time mean AUC0.20.31.5-0.71.2-0.1-0.3-0.00.50.00.0-0.01.0-0.50.1
Median of all reaction times0.10.20.8-0.60.9-0.1-0.3-0.00.3-0.0-0.00.00.8-0.5-0.3
Reaction time omissions0.91.21.9-0.70.91.3-1.11.31.01.41.4-1.40.9-0.50.8
Reaction time false alarm rate0.20.30.60.6-0.80.6-0.00.50.40.60.6-0.6-0.10.70.6
Reaction time premature initiation rate0.50.74.8-0.0-0.90.4-0.20.3-1.10.40.4-0.4-0.8-0.2-2.2
Reaction time premature initiations0.60.91.8-0.90.21.2-1.11.0-0.21.11.1-1.10.1-0.5-1.3
Std. dev. reaction times1.01.32.5-1.01.61.1-1.11.11.21.21.2-1.21.4-0.60.9
Reaction time trials completed0.40.61.5-0.91.20.7-1.00.70.70.60.6-0.61.0-0.30.8
Reaction time trials AUC0.30.41.2-0.81.10.5-0.90.50.60.40.4-0.40.9-0.30.8
Run reversals in cocaine runway, females0.60.61.80.6-1.3-0.50.6-0.5-0.9-0.5-0.50.5-0.9-0.1-1.2
Run reversals in cocaine runway, males0.60.63.01.5-0.70.00.50.1-0.40.10.1-0.1-0.41.70.9
Latency to leave start box in cocaine runway3.43.75.32.1-2.2-2.11.9-1.8-2.3-1.9-1.91.9-2.11.2-1.1
Latency to leave start box in cocaine runway, F0.80.91.80.9-0.9-0.90.8-0.8-1.3-0.9-0.90.9-1.20.2-0.8
Latency to leave start box in cocaine runway, M3.02.94.82.2-1.7-1.81.9-1.6-1.6-1.6-1.61.6-1.71.90.0
Std. dev. time between licks in bursts0.20.20.90.7-0.4-0.50.3-0.50.2-0.5-0.50.5-0.11.00.4
Total sessions with >9 infusions2.12.33.51.4-1.7-1.91.7-1.9-1.0-1.8-1.81.8-1.50.2-0.7
Short access day 1 total inactive lever presses1.82.02.81.5-1.6-1.61.5-1.5-1.1-1.7-1.71.7-1.40.4-0.6
Short access day 10 total inactive lever presses0.91.01.51.1-1.0-1.11.1-1.1-0.2-1.2-1.21.2-0.60.70.7
Short access day 1 total infusions1.01.12.60.9-1.0-1.61.0-1.2-0.3-1.3-1.31.3-0.90.3-0.3
Short access day 10 total infusions4.55.08.51.8-2.2-2.92.1-2.5-2.1-2.6-2.62.6-2.2-0.0-2.0
Short access total infusions1.71.93.61.2-1.4-1.91.4-1.8-0.8-1.7-1.71.7-1.30.1-1.0
Short access day 1 locomotion0.50.51.50.2-0.8-1.00.5-0.7-0.6-0.7-0.70.7-0.7-0.3-1.2
Short access day 10 total locomotion2.22.43.91.0-1.4-1.81.4-1.9-1.7-1.7-1.71.7-1.3-0.4-2.0
Short access total locomotion1.71.84.50.7-1.4-1.51.1-1.6-1.4-1.2-1.21.2-1.3-0.5-2.1
One hour access (0.3 mA shock)3.43.96.52.1-1.6-2.52.2-2.3-1.4-2.4-2.42.4-1.81.1-0.2
Compulsive drug intake3.43.45.2-1.41.62.3-2.01.92.22.02.0-2.02.2-0.61.2
One hour access (shock baseline)4.04.77.52.2-1.7-2.72.4-2.3-1.9-2.5-2.52.5-2.31.4-0.2
Social response proportion0.30.31.50.7-0.7-0.10.3-0.2-0.6-0.1-0.10.1-0.71.20.0
Social responses0.50.71.80.20.21.0-0.60.80.61.01.0-1.00.41.31.1
Social time1.21.63.7-0.81.41.2-1.31.11.91.11.1-1.11.70.11.5
Soleus weight1.02.87.52.1-0.9-1.71.9-1.8-0.4-1.7-1.71.7-1.12.71.2
Bone: stiffness0.30.53.4-0.0-0.5-0.30.3-0.3-1.9-0.3-0.30.3-0.8-0.0-1.3
Tibialis anterior weight4.214.327.7-4.93.23.9-4.43.82.33.83.8-3.83.2-5.3-1.5
Time to tail flick, vehicle, before self-admin0.70.82.40.2-0.8-1.00.7-0.8-1.0-0.8-0.80.8-1.1-0.5-1.5
Time to tail flick, vehicle, after self-admin0.10.10.6-0.20.0-0.3-0.1-0.30.2-0.2-0.20.2-0.0-0.8-0.7
Time to tail flick, test, before self-admin0.80.82.00.6-1.4-0.60.8-0.8-1.1-0.7-0.70.7-1.1-0.3-1.0
Time to tail flick, test, after self-admin0.10.10.3-0.0-0.10.4-0.00.2-0.20.30.3-0.3-0.00.40.6
Delta time to tail flick, vehicle, before/after SA0.10.10.3-0.20.50.4-0.40.20.50.20.2-0.20.5-0.00.5
Delta time to tail flick, test, before/after SA2.11.92.8-1.11.71.5-1.31.41.41.61.6-1.61.50.11.2
Tibia length0.20.73.1-1.10.10.7-0.50.6-0.70.60.6-0.6-0.2-0.9-1.8
Ambulatory time before self-admin0.70.71.2-1.11.10.9-0.90.8-0.11.01.0-1.00.6-0.1-0.6
Ambulatory time after self-admin0.40.51.80.1-0.2-0.30.5-0.7-1.4-0.7-0.70.7-0.7-0.1-0.9
Bone: tissue strength0.20.20.40.6-0.2-0.50.5-0.5-0.1-0.5-0.50.5-0.40.60.4
Total heroin consumption5.26.18.2-2.92.22.8-2.82.82.52.82.8-2.82.3-1.40.3
Bone: trabecular number0.30.41.70.1-0.6-0.40.4-0.4-1.1-0.4-0.40.4-0.8-0.5-1.3
Bone: trabecular spacing0.91.23.1-0.91.60.5-1.00.51.80.50.5-0.51.60.11.7
Bone: trabecular thickness0.70.81.71.2-1.0-0.81.1-0.8-1.2-0.8-0.80.8-1.30.7-0.4
Bone: trabecular tissue density0.70.92.41.4-0.7-0.81.2-0.8-0.2-0.8-0.80.8-0.71.61.2
Water consumed over 24 hours0.20.30.5-0.1-0.10.7-0.50.70.20.70.7-0.7-0.10.5-0.1
Number of responses in last shaping day0.20.20.5-0.40.30.3-0.50.40.70.30.3-0.30.4-0.20.3