Hub : Genes

Mrps10

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Mrps10 0.47 0.13 0.0e+00 0.36 0.39 0.38 0.38 2.3e-20 4.3e-22 1.6e-21 4.0e-21
2 Liver alternative polyA NM_001389252.2 0.14 0.08 1.0e-14 0.12 0.13 0.13 0.07 6.6e-13 8.5e-14 5.7e-14 3.2e-08
3 LHb gene expression Mrps10 0.56 0.15 2.6e-12 0.44 0.38 0.46 0.44 1.3e-11 7.6e-10 1.9e-12 9.6e-12
4 NAcc gene expression Mrps10 0.2 0.07 0.0e+00 0.31 0.33 0.31 0.32 5.6e-36 8.9e-39 1.1e-36 3.4e-38
5 Adipose alternative polyA NM_001389252.2 0.04 0.03 1.1e-03 0.02 0.02 0.01 0.01 2.2e-03 6.3e-03 7.3e-03 9.1e-03
6 Adipose alternative polyA XM_039083813.1 0.04 0.03 1.1e-03 0.02 0.02 0.01 0.01 1.8e-03 6.5e-03 7.1e-03 8.9e-03
7 pVTA gene expression Mrps10 0.46 0.11 0.0e+00 0.45 0.48 0.48 0.47 1.5e-21 2.7e-23 6.0e-23 7.4e-23
8 Liver gene expression Mrps10 0.73 0.08 0.0e+00 0.52 0.5 0.53 0.5 3.2e-68 8.2e-63 6.4e-70 1.4e-63
9 Liver alternative polyA XM_039083813.1 0.14 0.08 8.5e-15 0.12 0.13 0.13 0.1 2.8e-13 4.9e-14 6.0e-14 7.4e-11
10 PL gene expression Mrps10 0.4 0.1 0.0e+00 0.5 0.52 0.51 0.51 1.2e-62 6.2e-67 1.9e-65 2.3e-65
11 Brain gene expression Mrps10 0.54 0.12 0.0e+00 0.54 0.5 0.54 0.55 4.7e-60 9.5e-54 1.3e-59 4.6e-60
12 Brain alternative polyA NM_001389252.2 0.07 0.07 4.4e-04 0.04 0.03 0.02 0.03 5.9e-05 6.4e-04 8.5e-03 4.0e-04
13 Brain alternative polyA XM_039083813.1 0.07 0.07 3.4e-04 0.05 0.03 0.02 0.04 4.3e-05 4.6e-04 5.2e-03 2.2e-04
14 Adipose mRNA stability Mrps10 0.11 0.06 2.1e-10 0.09 0.07 0.08 0.04 8.0e-10 1.6e-08 6.1e-09 8.9e-06
15 Adipose gene expression Mrps10 0.41 0.13 0.0e+00 0.23 0.2 0.21 0.03 7.5e-25 9.9e-22 3.2e-23 1.7e-04
16 OFC gene expression Mrps10 0.74 0.14 6.8e-12 0.41 0.34 0.37 0.39 8.6e-11 8.6e-09 1.3e-09 2.2e-10
17 Eye gene expression Mrps10 0.81 0.12 2.4e-07 0.41 0.28 0.36 0.36 2.4e-07 2.8e-05 1.5e-06 1.6e-06
18 IL gene expression Mrps10 0.4 0.15 6.7e-08 0.31 0.26 0.26 0.27 3.3e-08 8.0e-07 4.6e-07 3.7e-07
19 Eye mRNA stability Mrps10 0.61 0.17 5.2e-06 0.19 0.26 0.24 0.22 8.0e-04 7.9e-05 1.4e-04 2.6e-04
20 RMTg gene expression Mrps10 0.17 0.11 2.8e-03 0.11 0.1 0.16 0.13 8.2e-04 1.1e-03 5.4e-05 2.2e-04
21 Liver isoform ratio XM_006244465.4 0.11 0.07 8.6e-09 0.04 0.07 0.07 0.07 5.7e-05 4.4e-08 1.5e-08 1.7e-08
22 Liver isoform ratio NM_001389252.2 0.14 0.09 3.0e-08 0.04 0.07 0.07 0.08 9.7e-06 1.8e-08 3.7e-08 8.8e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.50.92.7-0.90.21.1-1.1-0.70.7-0.90.7-0.8-1.1-1.1-0.90.90.90.90.81.01.10.51.7-0.5-1.3
Area under the delay curve6.87.212.6-2.8-3.52.7-2.5-3.03.0-2.83.1-2.8-2.5-2.6-2.72.72.72.72.72.72.42.81.82.21.6
BMI with tail3.511.316.04.02.9-3.83.73.7-3.73.7-3.73.63.73.73.7-3.7-3.3-3.3-3.5-3.4-3.2-3.0-3.0-1.0-0.1
BMI without tail10.120.829.15.44.5-5.05.15.1-5.15.0-5.05.04.94.94.9-4.9-4.5-4.5-4.6-4.5-4.3-4.3-3.7-1.9-0.5
Body weight2.510.714.73.82.3-3.53.53.6-3.63.6-3.53.53.53.63.5-3.5-3.3-3.3-3.5-3.2-3.0-3.0-3.8-0.6-0.0
Weight adjusted by age0.20.20.60.80.4-0.50.70.6-0.60.6-0.70.60.60.60.6-0.6-0.2-0.2-0.1-0.20.0-0.4-0.60.00.0
Bone surface1.32.33.7-1.6-0.71.8-1.8-1.61.6-1.71.5-1.6-1.8-1.7-1.61.61.41.41.31.51.51.41.90.4-0.3
Bone volume0.61.12.8-1.1-0.21.2-1.2-1.01.0-1.10.9-1.0-1.2-1.2-1.11.11.01.00.91.01.10.81.7-0.0-0.7
Breakpoint value in progressive ratio session0.10.10.60.20.8-0.30.20.0-0.00.2-0.30.10.30.30.2-0.2-0.2-0.2-0.2-0.2-0.40.00.8-0.00.5
Number of licking bursts4.14.88.42.02.0-2.12.02.2-2.22.1-2.02.32.12.02.1-2.1-2.2-2.2-2.2-2.1-2.4-2.6-1.6-2.9-2.7
Context. condit. distance diff. score0.40.52.00.30.1-0.80.70.3-0.30.6-0.40.60.80.60.5-0.5-0.8-0.8-0.9-0.7-1.4-0.8-0.8-1.0-0.2
Locomotion velocity, session 10.80.93.51.00.3-1.11.10.7-0.70.9-0.70.81.11.00.8-0.8-0.8-0.8-0.7-0.7-1.1-0.4-0.90.81.9
Locomotion distance, session 12.53.14.31.91.9-2.12.01.7-1.71.9-1.81.92.02.11.9-1.9-1.7-1.7-1.7-1.8-1.8-1.6-1.6-0.71.0
Locomotion velocity, session 25.86.89.43.02.1-3.12.92.6-2.62.8-2.82.72.93.02.8-2.8-2.7-2.7-2.6-2.7-2.7-2.0-2.60.21.4
Locomotion distance, session 21.01.42.21.51.4-1.31.31.3-1.31.4-1.31.31.21.41.2-1.2-0.9-0.9-0.9-1.1-1.0-0.9-0.80.41.3
Locomotion velocity, session 30.50.64.30.80.5-0.90.90.7-0.70.8-0.60.60.90.90.6-0.6-0.6-0.6-0.5-0.7-0.7-0.3-0.40.72.1
Locomotion distance, session 31.01.15.5-0.8-0.60.7-0.8-1.01.0-0.90.8-1.0-0.9-0.7-0.80.80.80.80.80.90.51.30.61.92.3
Stereotopy head waving bouts, day 31.11.22.21.31.5-1.11.11.2-1.21.2-1.31.21.11.21.2-1.2-1.1-1.1-1.0-1.2-1.0-1.1-0.5-0.8-0.7
Stereotopy head waving duration, day 31.82.12.71.61.3-1.61.61.6-1.61.6-1.51.61.61.61.5-1.5-1.5-1.5-1.4-1.6-1.4-1.4-1.1-0.8-0.5
Locomotion velocity, session 70.20.21.00.40.1-0.60.70.4-0.40.4-0.30.30.70.40.2-0.2-0.5-0.5-0.7-0.4-1.0-0.10.20.10.7
Locomotion distance, session 70.10.10.60.20.1-0.40.50.1-0.10.2-0.20.20.50.20.1-0.1-0.3-0.3-0.5-0.1-0.80.00.3-0.00.7
Stereotopy head waving bouts, day 70.10.10.50.40.7-0.20.10.4-0.40.3-0.40.30.10.20.2-0.2-0.3-0.3-0.2-0.40.1-0.20.20.2-0.0
Stereotopy head waving duration, day 70.10.10.4-0.30.00.5-0.5-0.10.1-0.30.3-0.3-0.5-0.4-0.40.40.30.30.50.30.60.10.50.1-0.5
Locomotion velocity, session 80.70.81.40.90.7-1.11.10.9-0.91.0-0.81.01.11.00.9-0.9-0.8-0.8-0.7-0.9-1.2-0.9-0.9-0.30.7
Locomotion distance, session 81.01.42.91.11.2-1.41.31.1-1.11.3-1.11.31.31.21.1-1.1-1.2-1.2-1.3-1.2-1.7-1.2-0.8-0.80.6
Degree of sensitization distance1.51.52.21.20.8-1.21.41.3-1.31.3-1.11.31.51.11.1-1.1-1.2-1.2-1.4-1.2-1.4-1.3-0.4-1.5-1.2
Degree of sensitization stereotypy0.70.81.5-0.7-0.21.0-1.1-0.80.8-0.90.8-0.9-1.1-1.0-0.90.90.80.80.90.81.20.91.20.90.1
Conditioned locomotion2.12.44.8-1.2-0.71.4-1.4-1.61.6-1.51.2-1.6-1.4-1.3-1.31.31.71.71.71.61.82.02.21.91.3
Cocaine response after cond. corrected0.30.30.5-0.6-0.70.7-0.7-0.50.5-0.60.6-0.6-0.7-0.5-0.50.50.60.60.60.50.50.50.10.70.5
Cocaine response after cond. not corrected0.60.71.7-0.7-0.80.9-0.9-0.60.6-0.80.8-0.8-1.0-0.8-0.80.80.80.80.80.80.70.80.41.31.1
Cocaine response before conditioning0.10.21.80.30.4-0.20.10.2-0.20.1-0.2-0.0-0.00.1-0.00.0-0.1-0.1-0.10.1-0.30.30.21.01.3
Saline control response0.10.10.60.1-0.5-0.10.1-0.10.10.10.00.00.10.20.1-0.1-0.0-0.0-0.0-0.10.20.1-0.50.70.8
Bone: connectivity density0.91.43.2-1.20.21.4-1.5-1.01.0-1.20.9-1.1-1.5-1.4-1.11.11.11.11.01.11.20.71.8-0.6-1.5
Bone: cortical apparent density0.81.02.6-0.8-1.30.8-0.9-1.01.0-0.91.0-1.0-0.9-0.7-0.80.81.11.11.11.10.91.10.41.61.2
Bone: cortical area0.40.71.91.11.4-0.80.80.8-0.80.7-1.00.60.80.80.7-0.7-0.6-0.6-0.8-0.8-0.50.00.60.81.3
Bone: cortical porosity0.10.11.10.10.4-0.10.20.3-0.30.2-0.20.20.2-0.00.1-0.1-0.1-0.1-0.1-0.1-0.2-0.30.3-1.0-1.0
Bone: cortical porosity0.10.10.60.10.4-0.10.20.2-0.20.1-0.20.10.2-0.00.0-0.0-0.1-0.1-0.0-0.1-0.2-0.10.5-0.8-0.6
Bone: cortical thickness0.71.23.21.51.8-1.21.21.1-1.11.1-1.40.91.11.21.2-1.2-0.9-0.9-1.0-1.1-0.8-0.20.30.81.2
Bone: cortical thickness0.10.11.1-0.10.30.0-0.1-0.10.1-0.1-0.1-0.0-0.0-0.00.0-0.0-0.0-0.0-0.0-0.20.0-0.00.3-0.6-1.1
Bone: cortical tissue density0.60.82.2-0.7-1.30.7-0.9-0.90.9-0.81.0-0.9-0.8-0.7-0.70.71.01.01.01.00.81.00.21.51.1
Condit. Reinf. active minus inactive responses2.22.53.51.41.9-1.61.61.4-1.41.6-1.61.61.71.61.6-1.6-1.7-1.7-1.7-1.6-1.6-1.6-0.6-1.8-1.2
Condit. Reinf. active-inactive response ratio0.70.72.60.61.1-0.80.70.6-0.60.7-0.80.80.80.70.8-0.8-0.8-0.8-0.9-0.9-0.9-0.9-0.3-1.4-1.6
Condit. Reinf. active responses3.03.75.01.92.2-2.12.11.9-1.92.0-2.02.02.12.01.9-1.9-2.1-2.1-2.2-2.0-2.0-1.9-1.0-1.8-0.5
Condit. Reinf. inactive responses1.92.22.71.51.5-1.61.61.6-1.61.6-1.41.61.61.61.5-1.5-1.7-1.7-1.5-1.6-1.5-1.5-1.1-1.10.5
Incentive salience index mean2.32.84.01.71.9-1.92.01.7-1.71.8-1.71.82.01.81.7-1.7-1.7-1.7-1.8-1.7-1.7-1.6-0.8-1.3-0.3
Condit. Reinf. lever presses3.64.86.52.42.1-2.52.62.3-2.32.4-2.32.32.52.52.3-2.3-2.2-2.2-2.2-2.2-2.2-2.0-1.8-0.80.5
Condit. Reinf. active minus inactive responses0.10.10.6-0.10.30.0-0.00.3-0.30.10.00.2-0.1-0.0-0.00.00.10.10.10.1-0.2-0.5-0.1-0.8-0.4
Condit. Reinf. active-inactive response ratio1.01.12.30.71.0-0.80.81.2-1.21.0-0.91.10.80.80.8-0.8-1.0-1.0-0.9-1.1-1.1-1.5-1.3-1.5-1.1
Condit. Reinf. active responses0.00.10.2-0.10.20.2-0.10.1-0.1-0.00.2-0.0-0.2-0.2-0.20.20.40.40.50.50.1-0.10.3-0.10.3
Condit. Reinf. inactive responses0.30.42.6-0.2-0.00.3-0.3-0.30.3-0.30.3-0.4-0.3-0.2-0.30.30.60.60.70.80.60.70.81.01.6
Condit. Reinf. lever presses0.30.41.00.60.9-0.60.70.8-0.80.7-0.60.80.60.60.6-0.6-0.5-0.5-0.5-0.4-0.8-0.9-0.2-1.0-0.4
Condit. Reinf. lever reinforcers received0.00.10.2-0.20.10.2-0.20.1-0.1-0.10.2-0.1-0.3-0.2-0.20.20.40.40.50.50.1-0.10.3-0.00.4
Conditioned reinforcement - actives1.11.12.6-0.9-1.20.9-0.9-1.01.0-1.01.1-1.1-0.9-0.9-1.11.10.70.70.70.80.71.31.11.61.6
Conditioned reinforcement - inactives0.30.41.10.70.7-0.60.70.8-0.80.6-0.50.50.50.50.3-0.3-0.7-0.7-0.8-0.5-0.8-0.10.30.51.0
Conditioned locomotion0.00.10.4-0.0-0.5-0.10.0-0.00.00.00.0-0.00.00.20.1-0.1-0.3-0.3-0.4-0.2-0.20.1-0.60.30.2
Patch foraging indifference point 0 sec0.81.31.71.20.9-1.21.01.1-1.11.1-1.11.11.11.21.3-1.3-1.2-1.2-1.2-1.3-1.2-1.1-1.0-0.4-0.6
Patch foraging indifference point AUC0.91.04.71.21.7-1.00.90.9-0.90.9-1.00.70.80.90.6-0.6-0.8-0.8-0.9-0.9-0.7-0.20.51.12.2
Delay disc. indifference point, 0s delay1.01.01.5-1.0-1.01.2-1.1-1.11.1-1.11.1-1.0-1.0-1.0-0.80.81.21.21.21.11.20.91.00.3-0.0
Delay disc. indifference point, 16s delay10.710.816.8-3.3-4.13.4-3.2-3.53.5-3.43.6-3.4-3.1-3.2-3.33.33.43.43.43.33.23.52.33.01.9
Delay disc. indifference point, 2s delay1.71.95.4-1.5-2.31.4-1.3-1.81.8-1.51.7-1.5-1.1-1.2-1.21.21.31.31.31.21.21.40.20.90.7
Delay disc. indifference point, 24s delay0.70.61.4-1.0-1.20.8-0.8-1.01.0-0.90.9-0.8-0.7-0.8-0.80.80.80.80.80.80.70.70.10.2-0.0
Delay disc. indifference point, 4s delay2.62.84.5-1.4-2.01.5-1.2-1.91.9-1.61.8-1.7-1.2-1.4-1.51.51.61.61.71.61.42.11.52.12.1
Delay disc. indifference point, 8s delay4.14.36.6-2.1-2.62.0-1.9-2.42.4-2.12.3-2.2-1.9-2.0-2.12.12.12.12.02.01.72.31.61.91.5
Indifference point function ln k0.30.42.3-0.8-1.50.6-0.6-0.80.8-0.70.8-0.7-0.5-0.5-0.40.40.60.60.70.60.60.5-0.70.1-0.5
Indifference point function log k0.30.42.3-0.8-1.50.6-0.6-0.80.8-0.70.8-0.7-0.5-0.5-0.40.40.60.60.70.60.60.5-0.70.1-0.5
Patch foraging total patch changes 0 sec0.91.51.91.31.0-1.31.21.2-1.21.3-1.21.31.21.31.4-1.4-1.3-1.3-1.3-1.3-1.3-1.2-1.1-0.5-0.6
Patch foraging total patch changes 12 sec0.91.22.01.41.4-1.31.21.0-1.01.1-1.11.01.21.21.1-1.1-1.1-1.1-1.1-1.1-1.0-0.4-0.00.71.4
Patch foraging total patch changes 18 sec1.11.42.91.51.7-1.31.21.3-1.31.3-1.31.21.21.31.1-1.1-1.1-1.1-1.1-1.2-1.0-0.70.00.61.4
Patch foraging total patch changes 24 sec0.30.41.01.00.7-0.60.70.9-0.90.7-0.60.70.70.50.4-0.4-0.5-0.5-0.6-0.6-0.6-0.40.30.40.7
Patch foraging total patch changes 6 sec2.33.45.02.01.8-2.21.91.8-1.82.0-1.91.82.02.12.0-2.0-2.0-2.0-2.2-2.0-2.1-1.6-1.4-0.50.2
Patch foraging time to switch 0 sec3.35.07.8-2.8-2.62.5-2.6-2.72.7-2.52.5-2.4-2.4-2.3-2.22.22.32.32.22.32.21.81.00.2-0.8
Patch foraging water rate 0 sec1.62.65.82.21.6-1.81.91.8-1.81.7-1.71.51.71.61.3-1.3-1.4-1.4-1.4-1.4-1.6-0.6-0.21.42.4
Patch foraging water rate 12 sec3.65.68.52.92.2-2.62.92.7-2.72.7-2.62.62.82.52.4-2.4-2.3-2.3-2.2-2.4-2.1-2.1-1.3-1.00.0
Patch foraging water rate 18 sec1.01.42.31.30.6-1.41.51.2-1.21.3-1.11.31.51.31.2-1.2-1.2-1.2-1.2-1.1-1.4-1.1-0.9-0.7-0.4
Patch foraging water rate 24 sec1.41.93.11.70.6-1.51.81.6-1.61.6-1.41.61.71.51.5-1.5-1.2-1.2-1.2-1.2-1.3-1.3-1.6-0.40.1
Patch foraging water rate 6 sec0.20.21.90.60.4-0.10.50.4-0.40.3-0.20.20.30.1-0.10.10.20.20.30.20.10.21.00.81.4
Seeking ratio, delayed vs. immediate footshock1.41.62.9-1.6-1.51.4-1.4-1.71.7-1.41.5-1.4-1.3-1.2-1.21.21.21.21.21.21.21.10.70.3-0.2
Distance traveled before self-admin0.10.10.30.30.1-0.30.40.2-0.20.3-0.30.20.30.20.1-0.1-0.3-0.3-0.3-0.3-0.3-0.1-0.30.20.6
Distance traveled after self-admin3.23.64.52.01.8-2.02.12.1-2.12.1-2.02.12.02.02.0-2.0-1.9-1.9-1.8-1.9-1.8-2.0-1.7-1.2-0.4
Extensor digitorum longus weight0.10.51.50.6-0.2-0.80.90.6-0.60.7-0.50.70.90.70.6-0.6-0.7-0.7-0.8-0.5-1.0-0.6-1.2-0.5-0.1
Bone: elastic displacement0.20.30.7-0.5-0.80.6-0.5-0.50.5-0.50.5-0.5-0.5-0.5-0.50.50.60.60.50.60.60.50.00.50.4
Bone: elastic work0.00.00.30.10.1-0.00.10.2-0.20.1-0.20.10.10.00.1-0.1-0.3-0.3-0.3-0.3-0.2-0.1-0.1-0.3-0.5
Bone: endosteal estimation0.40.91.9-1.2-1.41.1-1.0-1.11.1-1.01.2-1.0-1.0-1.1-1.11.10.90.90.81.00.70.70.40.1-0.1
Bone: endosteal perimeter0.00.00.1-0.20.00.1-0.0-0.10.1-0.10.1-0.1-0.1-0.1-0.20.2-0.0-0.0-0.20.00.00.10.3-0.10.3
Epididymis fat weight1.94.58.82.21.6-2.12.12.3-2.32.2-2.32.22.02.22.2-2.2-2.2-2.2-2.2-2.2-1.9-2.2-3.0-0.9-1.1
Delta time in closed arm before/after self-admin0.40.41.50.2-0.2-0.50.40.3-0.30.4-0.30.40.50.50.6-0.6-0.6-0.6-0.7-0.6-0.6-0.7-1.2-0.9-1.0
Delta time in open arm before/after self-admin0.30.31.8-0.50.30.5-0.6-0.60.6-0.60.4-0.5-0.5-0.6-0.50.50.40.40.40.40.40.51.4-0.2-0.3
Diff in mean of infusions in LGA sessions0.40.41.00.81.0-0.80.70.6-0.60.7-0.70.60.80.70.6-0.6-0.5-0.5-0.6-0.4-0.8-0.40.40.20.5
Delay discount exponential model param6.56.912.02.73.5-2.62.42.9-2.92.7-3.02.72.42.52.6-2.6-2.7-2.7-2.6-2.6-2.4-2.8-1.7-2.2-1.7
Extinction: sum of active levers before priming0.10.10.20.10.5-0.30.10.1-0.10.2-0.30.20.20.30.3-0.3-0.3-0.3-0.4-0.4-0.4-0.2-0.2-0.00.2
Active lever presses in extinction session 60.30.30.70.50.2-0.80.60.3-0.30.5-0.40.40.80.70.6-0.6-0.8-0.8-0.7-0.6-0.8-0.1-0.40.10.8
Bone: final force0.30.51.40.81.2-0.80.70.6-0.60.7-0.80.60.70.70.6-0.6-0.7-0.7-0.9-0.8-0.8-0.40.3-0.30.2
Bone: final moment0.30.51.10.81.0-0.80.80.6-0.60.6-0.70.60.70.70.6-0.6-0.7-0.7-0.9-0.7-0.7-0.20.30.10.7
Food consumed during 24 hour testing period0.50.61.01.00.9-0.90.80.9-0.90.8-0.90.70.70.90.8-0.8-0.7-0.7-0.7-0.7-0.7-0.3-0.40.71.0
Glucose5.07.511.52.93.4-2.92.72.9-2.92.9-3.02.92.72.92.9-2.9-2.8-2.8-2.8-2.8-2.9-2.8-1.8-1.8-0.8
Heart weight1.52.12.6-1.2-1.61.5-1.3-1.51.5-1.41.4-1.4-1.4-1.4-1.61.61.61.61.41.51.41.51.01.51.4
Delay discount hyperbolic model param5.66.010.82.53.3-2.42.32.8-2.82.5-2.82.62.22.32.4-2.4-2.5-2.5-2.4-2.4-2.2-2.6-1.6-2.1-1.6
Intermittent access intake day 1-15 change0.10.10.60.40.3-0.30.30.1-0.10.2-0.20.10.30.20.2-0.2-0.1-0.1-0.2-0.0-0.10.20.80.40.5
Intermittent access intake escalation0.00.00.80.20.3-0.00.0-0.00.0-0.0-0.1-0.00.1-0.1-0.00.00.10.10.00.20.10.20.90.10.1
Intermittent access intake escalation 20.10.10.30.50.2-0.50.50.2-0.20.3-0.30.30.60.50.5-0.5-0.3-0.3-0.3-0.2-0.30.10.40.20.5
Intermitt. access day 1 inactive lever presses0.80.91.61.00.9-0.91.01.3-1.31.0-0.90.90.90.90.9-0.9-1.1-1.1-1.1-1.1-1.0-0.8-0.4-0.5-0.1
Intermitt. access day 15 inactive lever presses1.71.92.51.61.6-1.51.51.4-1.41.4-1.61.41.41.61.6-1.6-1.4-1.4-1.3-1.4-1.4-1.1-0.9-0.60.1
Intermitt. access escalation Index0.10.10.7-0.1-0.1-0.20.0-0.10.10.1-0.20.10.10.20.3-0.3-0.4-0.4-0.4-0.4-0.3-0.3-0.8-0.3-0.5
Intermittent access day 1 total infusions0.40.51.00.40.4-0.60.50.8-0.80.6-0.60.60.40.60.6-0.6-0.8-0.8-0.9-0.8-1.0-0.9-0.9-0.7-0.7
Intermittent access day 15 total infusions0.20.30.80.30.5-0.40.30.5-0.50.4-0.40.40.30.30.4-0.4-0.6-0.6-0.7-0.5-0.7-0.50.1-0.7-0.9
Intermittent access terminal intake (last 3 days)0.10.10.70.10.2-0.20.10.3-0.30.2-0.10.20.10.10.2-0.2-0.3-0.3-0.5-0.2-0.5-0.40.0-0.7-0.8
Intermittent access total infusions0.10.21.1-0.1-0.1-0.20.00.3-0.30.2-0.10.20.10.10.2-0.2-0.4-0.4-0.5-0.3-0.6-0.5-0.3-0.8-1.0
Intermittent access day 1 locomotion0.50.51.60.1-0.0-0.50.20.4-0.40.4-0.30.40.30.40.5-0.5-0.9-0.9-1.1-0.9-1.0-0.8-1.3-1.0-1.3
Intermittent access day 15 total locomotion1.01.12.00.70.8-1.20.90.4-0.40.9-0.90.91.11.11.1-1.1-1.4-1.4-1.4-1.3-1.3-0.9-0.7-1.3-0.9
Intermittent access total locomotion0.40.42.7-0.1-0.1-0.30.10.1-0.10.2-0.10.20.30.30.4-0.4-0.7-0.7-0.9-0.7-0.8-0.7-0.7-1.5-1.6
Intermittent access standard deviation3.94.25.6-2.1-2.32.4-2.3-1.91.9-2.22.2-2.1-2.3-2.3-2.12.12.22.22.12.32.11.91.51.2-0.1
Left kidney weight0.41.211.81.10.2-0.90.80.5-0.50.6-0.80.40.70.90.5-0.5-0.7-0.7-0.8-0.6-0.60.3-0.92.33.4
Right kidney weight0.30.910.60.5-0.2-0.40.4-0.10.10.2-0.3-0.00.20.40.1-0.1-0.2-0.2-0.3-0.1-0.30.7-0.52.53.3
Cocaine induced anxiety0.50.61.50.40.5-0.80.60.4-0.40.6-0.60.60.60.91.0-1.0-0.8-0.8-0.8-0.7-0.8-0.7-1.2-0.8-0.7
Post-drug Anxiety0.10.10.7-0.0-0.0-0.30.20.1-0.10.2-0.10.20.20.40.5-0.5-0.2-0.2-0.2-0.1-0.5-0.4-0.8-0.5-0.4
Baseline Anxiety0.50.50.9-0.6-1.00.8-0.6-0.50.5-0.60.8-0.6-0.6-0.8-0.90.90.80.80.70.80.50.50.60.70.5
Tail length1.33.95.92.42.4-2.12.12.4-2.42.2-2.32.22.02.02.0-2.0-2.0-2.0-2.0-1.9-1.7-1.8-1.3-0.50.2
Length with tail0.10.31.60.5-0.1-0.30.30.4-0.40.4-0.40.30.20.40.3-0.3-0.4-0.4-0.5-0.4-0.0-0.1-1.01.31.1
Length without tail2.65.69.7-2.5-3.12.6-2.5-2.42.4-2.52.5-2.5-2.5-2.4-2.42.42.22.22.22.32.52.40.82.51.4
Times rat made contact with spout5.26.08.12.31.8-2.52.52.6-2.62.6-2.32.72.52.42.5-2.5-2.4-2.4-2.4-2.3-2.5-2.8-2.5-2.5-2.1
Lifetime Intake0.10.20.3-0.6-0.60.4-0.6-0.30.3-0.40.5-0.4-0.6-0.5-0.40.40.30.30.20.40.10.20.2-0.0-0.3
Liver weight, left0.50.91.71.21.0-1.01.00.7-0.70.9-1.00.91.01.11.0-1.0-0.9-0.9-1.0-0.8-0.7-0.4-0.40.71.3
Liver weight, right0.50.81.41.11.2-0.91.01.0-1.01.0-1.11.00.91.01.0-1.0-0.9-0.9-0.9-0.9-0.6-0.8-0.5-0.10.2
Locomotor activity2.33.76.31.91.5-2.12.02.2-2.22.1-1.92.01.92.01.9-1.9-1.9-1.9-1.9-1.8-2.0-2.0-2.5-0.9-0.3
Locomotor testing distance2.23.67.61.81.1-2.12.02.0-2.02.0-1.82.01.92.12.0-2.0-1.9-1.9-2.0-1.9-2.0-2.0-2.8-1.0-0.2
Locomotor testing rearing2.74.25.72.31.8-2.32.32.4-2.42.3-2.12.22.22.22.1-2.1-2.0-2.0-2.1-2.0-2.0-1.9-2.1-0.30.7
Locomotion in novel chamber0.60.71.4-0.9-1.20.7-0.8-1.11.1-0.90.9-0.9-0.7-0.8-0.90.90.70.70.60.70.30.90.70.70.3
Locomotion in novel chamber post-restriction2.02.45.8-1.1-1.21.3-1.2-1.41.4-1.31.4-1.5-1.3-1.4-1.61.61.51.51.51.51.51.91.92.42.1
Fecal boli incidents, locomotor time 10.70.83.8-0.5-1.00.6-0.5-0.70.7-0.60.8-0.8-0.6-0.7-0.90.90.70.70.60.70.51.10.61.61.9
Change in fecal boli incidents, locomotor task0.00.00.3-0.0-0.2-0.0-0.0-0.30.3-0.10.1-0.10.00.00.0-0.00.20.20.20.10.30.30.10.6-0.0
Time >=10cm from walls, locomotor time 10.30.30.80.4-0.2-0.70.60.4-0.40.6-0.30.50.70.60.5-0.5-0.6-0.6-0.6-0.6-0.9-0.4-0.80.00.2
Bouts of movement, locomotor time 10.20.31.6-0.6-0.10.6-0.6-0.20.2-0.40.4-0.3-0.6-0.5-0.40.40.40.40.40.50.3-0.20.2-1.0-1.2
Total resting periods, locomotor time 10.20.21.5-0.10.5-0.0-0.00.4-0.40.1-0.20.2-0.00.10.2-0.2-0.1-0.1-0.1-0.1-0.2-0.6-0.2-1.2-1.2
Rest time, locomotor task time 10.70.81.4-1.0-0.50.9-1.0-1.01.0-1.00.9-1.0-1.0-1.0-0.90.90.90.90.90.90.70.91.20.30.2
Distance moved, locomotor task time 10.00.00.10.20.0-0.20.30.3-0.30.2-0.20.30.20.10.0-0.0-0.2-0.2-0.2-0.2-0.2-0.3-0.4-0.2-0.2
Vertical activity count, locomotor time 10.30.31.1-0.7-1.00.4-0.4-0.70.7-0.50.6-0.5-0.4-0.4-0.60.60.30.30.30.40.30.4-0.20.40.4
Time >=10cm from walls, locomotor time 20.80.91.90.80.3-1.21.10.6-0.60.9-0.90.91.21.00.9-0.9-1.1-1.1-1.1-1.1-1.4-0.7-1.3-0.40.3
Bouts of movement, locomotor time 20.10.10.20.50.5-0.20.40.5-0.50.4-0.40.40.30.30.4-0.4-0.1-0.1-0.0-0.1-0.2-0.40.1-0.3-0.3
Total resting periods, locomotor time 20.00.00.20.10.10.2-0.00.1-0.10.0-0.10.1-0.00.00.1-0.10.20.20.30.20.2-0.20.2-0.3-0.4
Rest time, locomotor task time 20.60.71.1-1.1-0.51.0-1.1-0.90.9-0.90.8-0.9-1.0-0.9-0.80.80.80.80.80.80.90.60.6-0.2-0.5
Distance moved, locomotor task time 20.80.92.01.11.4-1.01.11.3-1.31.0-1.11.11.00.80.9-0.9-0.9-0.9-0.9-0.8-1.0-1.0-0.3-0.8-0.5
Vertical activity count, locomotor time 20.10.10.6-0.2-0.20.10.0-0.30.3-0.20.3-0.2-0.0-0.2-0.30.30.10.10.10.30.00.30.40.30.7
Light reinforcement 11.73.14.32.01.6-2.01.92.0-2.01.9-1.81.81.81.81.7-1.7-1.9-1.9-2.0-1.9-2.1-1.5-1.6-0.10.7
Light reinforcement 21.52.13.51.51.8-1.31.41.9-1.91.6-1.51.71.31.21.3-1.3-1.2-1.2-1.3-1.2-1.5-1.8-0.8-1.5-1.0
Bone: marrow area0.51.12.0-1.3-1.41.2-1.0-1.21.2-1.11.2-1.1-1.0-1.1-1.21.21.01.00.91.00.80.80.50.20.0
Bone: maximum diameter0.10.31.60.60.7-0.50.60.4-0.40.4-0.50.30.60.50.3-0.3-0.3-0.3-0.4-0.4-0.40.10.40.51.2
Bone: maximum force0.00.10.40.00.5-0.00.00.0-0.00.0-0.10.10.0-0.0-0.00.0-0.2-0.2-0.3-0.2-0.3-0.10.6-0.7-0.5
Bone: maximum moment0.00.00.50.00.40.00.0-0.10.1-0.0-0.1-0.00.0-0.1-0.10.1-0.1-0.1-0.3-0.1-0.20.10.7-0.3-0.0
Mean time between licks in bursts1.82.53.9-1.7-1.41.9-1.6-1.61.6-1.61.6-1.4-1.6-1.8-1.61.61.61.61.61.61.70.81.5-0.8-2.0
Mean num. licks in bursts0.60.71.8-0.7-1.10.7-0.6-0.70.7-0.70.8-0.8-0.6-0.6-0.70.70.80.80.80.80.90.9-0.01.31.3
Cd content in liver0.91.01.6-1.2-0.91.1-0.9-1.11.1-1.11.1-1.1-0.9-1.1-1.21.21.11.11.11.00.81.01.30.30.2
Co content in liver0.20.31.40.1-0.5-0.50.40.2-0.20.4-0.10.40.60.30.3-0.3-0.5-0.5-0.5-0.6-0.7-0.7-1.2-0.9-0.6
Cu content in liver0.50.62.4-0.6-1.30.4-0.5-0.80.8-0.60.7-0.8-0.5-0.6-0.80.80.50.50.50.40.51.0-0.01.51.2
Fe content in liver0.60.82.2-0.9-1.50.8-0.7-0.80.8-0.81.0-0.8-0.7-0.9-1.01.00.90.90.91.00.40.80.40.80.5
K content in liver0.60.64.8-0.8-1.20.7-0.7-0.60.6-0.60.7-0.4-0.6-0.6-0.40.40.30.30.30.30.6-0.1-0.6-1.2-2.2
Mg content in liver1.51.54.2-1.4-2.11.2-1.3-1.51.5-1.31.3-1.4-1.2-1.1-1.11.10.90.90.91.01.41.3-0.11.40.5
Mn content in liver1.11.23.21.00.4-1.00.81.1-1.11.0-1.01.10.91.01.2-1.2-1.1-1.1-1.1-1.2-0.7-1.3-1.8-0.9-1.5
Na content in liver0.00.00.20.3-0.1-0.10.20.2-0.20.1-0.10.10.20.10.2-0.20.00.00.00.0-0.10.10.20.50.2
Rb content in liver6.07.49.5-2.9-3.12.8-2.8-3.03.0-2.92.9-3.0-2.7-2.7-2.82.82.72.72.72.82.82.91.92.31.3
Se content in liver0.10.20.30.40.1-0.40.40.4-0.40.4-0.30.40.40.50.4-0.4-0.4-0.4-0.4-0.4-0.4-0.3-0.50.10.5
Sr content in liver0.60.63.10.91.8-0.70.70.9-0.90.7-0.90.70.60.70.7-0.7-0.4-0.4-0.4-0.6-0.4-0.50.6-0.30.6
Zn content in liver4.14.57.0-2.2-2.72.0-1.9-2.42.4-2.22.2-2.4-1.9-2.0-2.12.12.12.12.12.02.12.61.42.21.4
Bone: minimum diameter0.10.20.80.60.9-0.50.50.4-0.40.4-0.60.40.40.40.4-0.4-0.5-0.5-0.6-0.5-0.4-0.10.40.30.5
Time in familiar zone, hab. session 10.60.53.80.90.4-0.60.60.7-0.70.6-0.60.40.60.70.5-0.5-0.4-0.4-0.4-0.4-0.40.1-0.21.61.9
Time in novel zone, hab. session 10.60.61.5-1.0-0.80.8-0.8-0.90.9-0.80.9-0.6-0.8-0.8-0.70.70.80.80.70.70.50.20.3-0.9-1.2
Total zone transitions, hab. session 13.95.59.22.63.0-2.62.62.3-2.32.6-2.62.62.62.62.6-2.6-2.2-2.2-2.1-2.3-2.2-2.3-1.5-1.4-0.1
Total locomotion distance, hab. session 14.05.68.12.82.8-2.72.72.4-2.42.6-2.72.62.72.72.6-2.6-2.2-2.2-2.1-2.3-2.2-2.0-1.6-0.80.5
Locomotion velocity, hab. session 13.75.27.32.72.7-2.62.62.3-2.32.5-2.62.42.62.62.5-2.5-2.2-2.2-2.1-2.2-2.1-1.9-1.6-0.70.6
Time in familiar zone, hab. session 22.92.96.7-1.8-2.61.9-1.8-1.51.5-1.82.0-1.7-1.8-1.9-1.91.91.81.81.71.81.71.40.90.8-0.5
Time in novel zone, hab. session 20.60.62.40.81.5-0.90.80.6-0.60.8-1.00.80.80.90.9-0.9-0.7-0.7-0.7-0.8-0.8-0.6-0.1-0.30.5
Total zone transitions, hab. session 23.24.27.41.92.7-2.11.92.0-2.02.1-2.22.21.92.12.2-2.2-2.0-2.0-2.1-2.0-1.8-2.3-1.5-2.1-1.4
Total locomotion distance, hab. session 22.93.96.62.12.6-2.12.02.0-2.02.1-2.22.11.92.12.2-2.2-1.8-1.8-1.9-1.8-1.7-2.1-1.3-1.6-1.1
Locomotion velocity, hab. session 22.33.26.01.92.5-1.91.71.8-1.81.9-2.01.91.71.92.0-2.0-1.6-1.6-1.7-1.6-1.5-1.8-1.1-1.4-1.0
Novel to familiar place preference ratio0.10.10.60.40.8-0.20.20.4-0.40.2-0.40.20.10.30.3-0.3-0.2-0.2-0.1-0.20.0-0.10.40.2-0.2
Novelty place preference0.00.00.30.10.40.0-0.10.1-0.1-0.0-0.1-0.1-0.10.00.1-0.10.00.00.20.00.20.20.50.50.0
Time in novel zone, NPP test0.10.10.40.10.50.1-0.20.1-0.1-0.1-0.1-0.1-0.2-0.00.0-0.00.10.10.20.10.20.30.60.5-0.0
Total zone transitions, NPP test6.49.111.43.23.1-3.43.33.1-3.13.3-3.13.33.33.23.1-3.1-3.1-3.1-3.0-3.1-3.1-3.0-2.4-1.9-0.1
Total locomotion distance, NPP test5.47.59.13.02.8-3.03.02.9-2.93.0-2.93.02.92.92.9-2.9-2.7-2.7-2.7-2.7-2.7-2.8-2.1-1.9-0.5
Locomotion velocity, NPP test5.98.410.33.12.9-3.23.23.1-3.13.1-3.03.13.13.13.1-3.1-2.9-2.9-2.8-2.8-2.9-3.0-2.3-2.0-0.7
Intraocular pressure0.60.81.9-1.2-1.40.9-1.0-1.11.1-1.01.2-1.0-0.9-0.9-1.01.00.70.70.60.80.50.7-0.00.20.2
Delta distance traveled before/after self-admin4.85.26.62.22.2-2.32.22.5-2.52.4-2.32.42.32.32.4-2.4-2.3-2.3-2.2-2.2-2.1-2.6-2.0-2.2-1.6
Delta ambulatory time before/after self-admin3.23.65.01.91.9-1.81.82.2-2.22.0-2.02.01.81.81.9-1.9-1.9-1.9-1.8-1.9-1.5-2.2-1.6-1.7-1.5
Parametrial fat weight5.310.313.83.73.4-3.43.43.5-3.53.5-3.53.53.33.43.3-3.3-3.4-3.4-3.3-3.4-3.0-3.2-2.5-1.6-0.2
Pavlov. Cond. lever latency1.92.53.7-1.9-1.51.8-1.9-1.61.6-1.81.7-1.6-1.8-1.8-1.61.61.51.51.51.61.41.01.0-0.2-1.1
Pavlov. Cond. magazine entry latency0.60.72.21.11.0-1.01.10.8-0.80.9-0.90.71.01.10.9-0.9-0.7-0.7-0.6-0.7-0.6-0.2-0.10.81.5
Pavlov. Cond. change in total contacts2.12.33.31.71.7-1.81.71.2-1.21.6-1.71.51.81.81.7-1.7-1.6-1.6-1.6-1.7-1.4-1.1-1.0-0.50.5
Pavlov. Cond. index score2.02.53.92.01.6-1.91.91.6-1.61.8-1.71.61.91.91.6-1.6-1.6-1.6-1.5-1.6-1.4-0.9-0.90.51.5
Pavlov. Cond. latency score1.41.83.11.71.3-1.51.61.3-1.31.4-1.41.21.51.51.3-1.3-1.3-1.3-1.2-1.3-1.2-0.5-0.60.81.8
Pavlov. Cond. lever contacts2.63.14.72.11.6-2.02.21.8-1.82.0-1.91.82.12.01.8-1.8-1.8-1.8-1.8-1.8-1.7-1.3-1.30.01.2
Pavlov. Cond. magazine entry number1.51.93.1-1.8-1.71.5-1.6-1.31.3-1.51.6-1.3-1.5-1.6-1.51.51.21.21.11.21.00.70.4-0.5-1.6
Pavlov. Cond. intertrial magazine entries0.60.71.2-1.1-0.70.9-1.0-1.11.1-1.01.0-0.9-0.9-0.9-0.90.90.80.80.60.90.80.70.6-0.10.3
Pavlov. Cond. lever-magazine prob. diff.1.82.23.51.91.4-1.71.91.5-1.51.7-1.61.51.81.81.5-1.5-1.4-1.4-1.4-1.4-1.3-0.9-0.80.41.4
Pavlov. Cond. response bias3.44.16.02.42.1-2.32.42.1-2.12.3-2.22.12.42.42.2-2.2-2.0-2.0-1.9-2.0-1.9-1.5-1.4-0.21.1
Pavlov. Cond. lever latency2.12.84.2-1.6-2.01.8-1.8-1.71.7-1.81.6-1.9-1.8-1.7-1.71.71.41.41.41.41.72.00.92.00.8
Pavlov. Cond. magazine entry latency1.51.83.01.31.7-1.51.41.2-1.21.4-1.31.41.41.31.3-1.3-1.4-1.4-1.4-1.3-1.6-1.4-0.2-1.4-0.4
Pavlov. Cond. change in total contacts1.92.63.81.61.5-1.71.71.9-1.91.8-1.41.81.71.61.6-1.6-1.5-1.5-1.5-1.5-1.8-2.0-1.0-1.7-0.6
Pavlov. Cond. index score3.84.86.22.32.5-2.42.42.2-2.22.4-2.22.42.42.32.2-2.2-2.2-2.2-2.1-2.1-2.4-2.4-1.1-2.1-0.5
Pavlov. Cond. latency score4.25.26.62.32.6-2.52.52.3-2.32.4-2.32.52.52.32.3-2.3-2.3-2.3-2.2-2.2-2.5-2.5-1.1-2.3-0.8
Pavlov. Cond. lever contacts2.23.04.01.81.9-1.91.91.8-1.81.9-1.72.01.91.81.8-1.8-1.6-1.6-1.6-1.5-1.9-2.0-1.1-1.8-0.4
Pavlov. Cond. magazine entry number0.50.71.1-0.8-1.01.0-0.9-0.80.8-0.90.7-0.9-1.0-0.8-0.80.80.80.80.80.71.10.9-0.10.8-0.0
Pavlov. Cond. intertrial magazine entries0.10.11.40.1-0.5-0.10.10.1-0.10.1-0.20.10.10.10.1-0.1-0.3-0.3-0.3-0.3-0.3-0.1-1.20.2-0.2
Pavlov. Cond. lever-magazine prob. diff.3.84.96.02.22.3-2.42.42.2-2.22.4-2.22.42.42.32.2-2.2-2.2-2.2-2.2-2.1-2.5-2.5-1.3-2.2-0.6
Pavlov. Cond. response bias0.60.91.60.91.2-1.01.10.9-0.91.0-0.81.11.10.90.9-0.9-0.7-0.7-0.7-0.6-1.1-1.2-0.2-1.3-0.1
Time in closed arm before self-admin0.30.30.8-0.60.20.7-0.6-0.30.3-0.50.4-0.4-0.7-0.6-0.50.50.60.60.60.60.70.20.6-0.5-0.9
Time in closed arm after self-admin0.30.32.8-0.4-0.40.4-0.40.0-0.0-0.20.2-0.1-0.5-0.4-0.20.20.20.20.20.10.4-0.3-0.9-0.9-1.7
Time in open arm before self-admin1.92.13.21.80.9-1.71.71.5-1.51.6-1.51.51.71.61.4-1.4-1.5-1.5-1.4-1.5-1.3-1.0-1.30.61.1
Time in open arm after self-admin0.40.40.80.80.8-0.70.80.6-0.60.7-0.70.70.90.70.5-0.5-0.7-0.7-0.6-0.7-0.4-0.40.30.10.5
Bone: periosteal estimation0.00.10.60.20.2-0.00.20.0-0.00.0-0.1-0.00.10.0-0.10.10.00.0-0.2-0.1-0.10.30.50.50.7
Bone: periosteal perimeter0.30.61.51.01.2-0.80.90.8-0.80.8-0.90.80.80.80.7-0.7-0.7-0.7-0.8-0.7-0.7-0.40.2-0.00.5
Bone: post-yield work0.10.11.7-0.2-0.0-0.10.1-0.10.10.00.10.10.20.0-0.00.0-0.2-0.2-0.4-0.2-0.4-0.5-0.2-1.3-0.7
Progressive ratio test 1 active lever presses0.50.61.50.60.7-0.60.51.1-1.10.7-0.60.80.50.50.6-0.6-0.6-0.6-0.6-0.5-0.6-1.0-0.5-1.2-1.2
Progressive ratio test 1 breakpoint0.40.41.00.60.5-0.50.51.0-1.00.7-0.50.70.40.40.6-0.6-0.5-0.5-0.5-0.4-0.6-0.9-0.4-1.0-0.9
Progressive ratio test 1 inactive lever presses0.30.30.90.70.6-0.50.61.0-1.00.6-0.50.50.50.50.4-0.4-0.7-0.7-0.6-0.6-0.6-0.40.3-0.20.3
Progressive ratio test 2 active lever presses0.60.61.00.90.7-0.90.91.0-1.00.9-0.70.90.90.80.8-0.8-0.8-0.8-0.8-0.8-0.9-0.7-0.2-0.5-0.2
Progressive ratio test 2 breakpoint1.11.21.71.20.9-1.31.21.3-1.31.2-1.01.21.31.11.1-1.1-1.2-1.2-1.2-1.1-1.2-1.1-0.4-0.8-0.4
Progressive ratio test 2 inactive lever presses0.30.30.60.60.7-0.70.60.7-0.70.6-0.50.50.60.60.6-0.6-0.6-0.6-0.7-0.6-0.8-0.40.1-0.40.1
Incentive Sensitization - Responses0.70.71.11.00.5-1.01.00.9-0.90.9-0.80.91.00.90.8-0.8-0.9-0.9-0.8-0.9-0.9-0.7-0.2-0.4-0.0
Incentive Sensitization - Breakpoint0.70.71.21.00.6-1.01.11.0-1.01.0-0.80.91.10.90.8-0.8-0.9-0.9-0.9-0.9-1.0-0.7-0.2-0.5-0.1
Sum of active levers in priming session hrs 5-60.90.94.3-0.5-0.40.6-0.6-0.90.9-0.80.7-0.9-0.6-0.6-0.90.90.70.70.60.70.61.31.51.62.1
Progressive ratio0.30.41.7-0.7-1.30.5-0.4-0.80.8-0.60.8-0.6-0.4-0.5-0.70.70.40.40.50.40.30.6-0.20.60.9
Food seeking constrained by brief footshock0.20.30.80.10.1-0.40.40.2-0.20.4-0.30.40.50.40.4-0.4-0.6-0.6-0.8-0.7-0.6-0.6-0.4-0.9-0.8
Seeking ratio, punishment vs. effort0.50.61.70.81.3-0.70.70.9-0.90.8-0.90.80.70.70.8-0.8-0.6-0.6-0.9-0.7-0.5-0.70.2-0.9-1.0
Retroperitoneal fat weight1.13.56.82.61.8-2.02.12.3-2.32.1-2.12.01.92.11.9-1.9-1.6-1.6-1.6-1.7-1.4-1.2-1.31.31.9
Reaction time number correct0.30.52.2-0.1-0.30.5-0.3-0.40.4-0.40.3-0.5-0.4-0.4-0.40.40.70.70.70.70.80.91.01.41.5
Reaction time mean minus median0.00.10.4-0.2-0.60.0-0.2-0.20.2-0.20.3-0.2-0.1-0.1-0.10.10.10.10.10.1-0.20.2-0.50.20.4
Reaction time mean minus median AUC0.30.40.8-0.8-0.90.7-0.8-0.50.5-0.70.7-0.7-0.8-0.7-0.70.70.50.50.60.60.30.4-0.10.20.1
Reaction time num false alarms0.50.71.0-1.0-0.70.8-1.0-1.01.0-0.90.9-1.0-0.9-0.8-0.80.80.70.70.60.70.60.90.61.00.8
Reaction time num false alarms AUC0.40.61.1-0.8-0.50.7-0.9-0.80.8-0.80.8-0.9-0.8-0.6-0.70.70.70.70.60.70.60.90.71.01.0
Reaction time trials correct on left0.30.52.2-0.1-0.30.5-0.3-0.40.4-0.40.3-0.5-0.4-0.4-0.40.40.70.70.70.70.80.91.01.41.5
Reaction time trials on left0.30.42.0-0.0-0.30.4-0.2-0.40.4-0.30.3-0.4-0.3-0.3-0.40.40.60.60.60.60.70.80.91.41.4
Reaction time mean0.30.42.8-0.7-1.10.4-0.5-0.30.3-0.30.5-0.2-0.4-0.5-0.40.40.00.00.00.1-0.1-0.4-1.1-1.1-1.7
Reaction time mean AUC0.30.43.5-0.6-0.80.3-0.5-0.20.2-0.30.3-0.1-0.4-0.4-0.30.3-0.1-0.1-0.1-0.0-0.2-0.5-1.0-1.2-1.9
Median of all reaction times0.30.43.3-0.6-1.00.4-0.4-0.10.1-0.20.3-0.1-0.4-0.4-0.30.3-0.1-0.1-0.2-0.0-0.1-0.5-1.2-1.2-1.8
Reaction time omissions0.60.84.10.8-0.1-0.90.80.8-0.80.9-0.80.90.80.90.9-0.9-0.7-0.7-0.7-0.7-1.1-0.9-2.0-0.2-0.3
Reaction time false alarm rate0.40.51.0-1.0-0.60.8-1.0-0.80.8-0.90.9-0.9-1.0-0.8-0.80.80.70.70.60.60.50.70.40.40.2
Reaction time premature initiation rate1.01.32.01.01.1-1.21.21.2-1.21.1-1.11.11.21.11.0-1.0-1.3-1.3-1.4-1.3-1.3-1.1-0.6-1.3-0.7
Reaction time premature initiations0.60.81.21.11.1-1.01.11.0-1.01.0-1.00.91.01.00.9-0.9-1.0-1.0-1.1-1.0-0.9-0.6-0.1-0.30.4
Std. dev. reaction times0.10.21.0-0.5-1.00.2-0.3-0.30.3-0.30.4-0.2-0.3-0.2-0.20.20.00.00.10.1-0.3-0.2-1.0-0.6-0.7
Reaction time trials completed0.30.42.0-0.0-0.30.4-0.2-0.40.4-0.30.3-0.4-0.3-0.3-0.40.40.60.60.60.60.70.80.91.41.4
Reaction time trials AUC0.20.31.90.1-0.20.3-0.1-0.20.2-0.20.2-0.3-0.2-0.2-0.30.30.50.50.50.50.60.70.91.31.4
Run reversals in cocaine runway, females0.50.50.90.90.5-0.80.90.7-0.70.8-0.80.70.90.80.6-0.6-0.6-0.6-0.5-0.7-0.5-0.4-0.80.30.8
Run reversals in cocaine runway, males0.10.10.30.20.1-0.0-0.00.1-0.10.00.10.0-0.00.00.1-0.10.40.40.20.50.20.10.60.30.4
Latency to leave start box in cocaine runway0.91.02.51.41.6-1.01.11.3-1.31.2-1.11.11.11.01.0-1.0-0.7-0.7-0.6-0.7-0.6-0.80.3-0.00.5
Latency to leave start box in cocaine runway, F0.20.22.10.10.80.3-0.10.4-0.4-0.00.10.0-0.3-0.3-0.30.30.50.50.60.60.6-0.01.40.10.3
Latency to leave start box in cocaine runway, M4.24.15.82.41.9-2.32.32.1-2.12.2-2.22.12.32.22.2-2.2-2.1-2.1-1.9-2.2-1.8-1.6-1.4-0.40.1
Std. dev. time between licks in bursts2.22.63.5-1.6-1.61.7-1.5-1.81.8-1.71.7-1.6-1.5-1.7-1.61.61.81.81.91.71.81.51.70.6-0.4
Total sessions with >9 infusions0.30.31.0-0.3-0.50.6-0.5-0.20.2-0.40.4-0.4-0.6-0.5-0.50.50.60.60.50.70.70.50.51.00.7
Short access day 1 total inactive lever presses0.20.22.30.10.10.20.00.1-0.1-0.10.2-0.2-0.2-0.2-0.40.40.30.30.30.30.20.50.91.01.5
Short access day 10 total inactive lever presses0.50.61.11.01.0-0.81.00.9-0.90.8-0.80.80.80.80.6-0.6-0.7-0.7-0.7-0.6-0.7-0.40.20.10.7
Short access day 1 total infusions1.01.01.9-0.8-0.81.1-0.9-0.70.7-0.91.0-1.0-1.0-1.1-1.11.11.01.01.01.21.01.01.41.01.0
Short access day 10 total infusions0.10.10.3-0.5-0.50.3-0.5-0.00.0-0.20.4-0.2-0.5-0.3-0.20.20.00.0-0.10.1-0.1-0.1-0.5-0.1-0.4
Short access total infusions0.60.61.1-1.0-1.00.9-1.0-0.70.7-0.91.0-0.9-1.0-0.9-0.90.90.70.70.70.80.60.60.40.50.1
Short access day 1 locomotion0.80.82.3-0.9-0.41.1-1.0-1.01.0-1.00.9-1.0-1.0-1.0-0.90.90.90.90.80.91.00.91.50.2-0.2
Short access day 10 total locomotion1.61.73.3-1.8-1.71.5-1.7-1.61.6-1.51.5-1.5-1.7-1.5-1.41.41.01.00.80.90.91.00.20.3-0.6
Short access total locomotion1.91.92.8-1.6-1.61.6-1.7-1.61.6-1.61.5-1.6-1.6-1.5-1.41.41.11.11.01.21.21.40.91.00.2
One hour access (0.3 mA shock)0.20.20.8-0.5-0.40.2-0.3-0.60.6-0.40.5-0.5-0.3-0.3-0.40.40.10.10.10.20.10.70.90.70.8
Compulsive drug intake0.10.10.80.00.1-0.30.3-0.10.10.1-0.00.10.30.30.1-0.1-0.2-0.2-0.3-0.1-0.30.10.10.20.9
One hour access (shock baseline)0.20.30.60.30.2-0.50.30.4-0.40.4-0.30.40.40.50.6-0.6-0.6-0.6-0.6-0.6-0.6-0.5-0.5-0.5-0.8
Social response proportion1.01.12.2-1.2-1.51.1-1.0-1.21.2-1.11.1-1.1-1.1-1.1-1.21.20.90.91.00.91.01.00.40.90.2
Social responses2.63.35.3-2.0-2.31.9-1.7-1.81.8-1.92.1-1.9-1.7-1.9-2.02.01.91.91.81.81.71.81.41.40.8
Social time2.63.47.3-1.2-1.41.6-1.2-1.41.4-1.51.6-1.7-1.4-1.6-1.81.82.02.02.11.92.02.22.32.62.7
Soleus weight0.41.01.61.11.2-1.21.21.0-1.01.1-1.01.11.11.11.0-1.0-0.9-0.9-1.1-0.8-1.3-0.9-0.6-0.30.9
Bone: stiffness0.10.10.9-0.20.30.3-0.3-0.20.2-0.30.2-0.2-0.3-0.4-0.30.30.20.20.10.10.00.31.0-0.1-0.3
Tibialis anterior weight0.20.61.30.80.4-0.80.80.8-0.80.8-0.70.80.80.80.9-0.9-0.8-0.8-0.9-0.6-0.7-0.9-1.1-0.6-0.1
Time to tail flick, vehicle, before self-admin0.90.92.2-0.6-1.01.0-0.7-0.40.4-0.81.0-0.7-0.8-1.1-1.11.11.31.31.21.30.90.81.50.50.5
Time to tail flick, vehicle, after self-admin2.12.33.4-1.7-1.41.6-1.7-1.61.6-1.61.7-1.6-1.9-1.5-1.51.51.71.71.41.51.31.30.71.10.9
Time to tail flick, test, before self-admin5.25.16.6-1.9-2.42.2-1.9-2.32.3-2.22.3-2.2-1.9-2.1-2.22.22.52.52.62.42.52.52.52.11.8
Time to tail flick, test, after self-admin1.01.02.2-0.7-0.11.1-0.9-0.70.7-0.90.8-0.9-1.1-1.0-1.11.11.11.11.01.11.21.01.31.21.5
Delta time to tail flick, vehicle, before/after SA0.40.40.8-0.7-0.10.6-0.8-0.70.7-0.70.4-0.7-0.9-0.5-0.50.50.50.50.30.40.50.70.00.90.8
Delta time to tail flick, test, before/after SA0.80.81.60.61.3-0.60.61.2-1.20.8-0.90.90.30.60.6-0.6-0.8-0.8-1.0-0.8-0.8-1.2-1.0-1.0-0.7
Tibia length1.85.19.62.83.1-2.42.42.6-2.62.4-2.62.42.32.52.4-2.4-2.2-2.2-2.2-2.2-1.7-1.7-0.8-0.11.6
Ambulatory time before self-admin0.10.10.9-0.1-0.70.00.0-0.30.3-0.10.2-0.20.0-0.1-0.20.2-0.0-0.00.1-0.00.10.4-0.30.70.9
Ambulatory time after self-admin3.13.44.02.01.6-2.02.02.0-2.02.0-1.92.01.91.91.9-1.9-2.0-2.0-1.9-2.0-1.8-1.9-1.9-1.1-0.2
Bone: tissue strength0.10.10.5-0.20.10.2-0.3-0.30.3-0.20.1-0.3-0.3-0.3-0.30.30.00.0-0.10.10.10.40.70.40.2
Total heroin consumption0.00.00.10.30.4-0.20.10.0-0.00.2-0.20.20.20.20.2-0.2-0.2-0.2-0.1-0.2-0.1-0.2-0.00.0-0.1
Bone: trabecular number0.71.12.9-0.9-0.01.2-1.2-0.90.9-1.10.8-1.0-1.3-1.1-1.01.01.11.11.01.21.21.01.70.4-0.0
Bone: trabecular spacing0.81.02.71.00.1-1.21.10.8-0.81.0-0.90.91.11.10.9-0.9-1.0-1.0-0.9-1.0-1.3-0.6-1.60.41.3
Bone: trabecular thickness1.21.53.6-1.2-0.31.5-1.3-1.01.0-1.21.0-1.1-1.4-1.4-1.21.21.31.31.21.21.50.91.9-0.2-1.2
Bone: trabecular tissue density0.20.31.9-0.1-0.00.3-0.2-0.30.3-0.30.3-0.4-0.2-0.2-0.30.30.50.50.50.50.70.81.11.11.4
Water consumed over 24 hours1.82.13.41.91.6-1.71.71.7-1.71.6-1.71.51.61.71.7-1.7-1.3-1.3-1.2-1.2-1.5-1.0-0.70.20.6
Number of responses in last shaping day0.10.10.30.50.1-0.50.50.3-0.30.4-0.30.30.50.40.4-0.4-0.4-0.4-0.3-0.4-0.4-0.20.0-0.10.1