Mob3a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression Mob3a 0.16 0.11 6.7e-04 0.11 0.11 0.1 0.11 1.6e-03 1.2e-03 1.9e-03 1.6e-03
2 NAcc gene expression Mob3a 0.14 0.07 0.0e+00 0.19 0.19 0.19 0.19 1.1e-21 4.8e-22 2.9e-21 7.1e-22
3 Brain gene expression Mob3a 0.17 0.1 1.0e-15 0.14 0.14 0.14 0.14 4.8e-13 7.4e-13 4.8e-13 1.5e-12
4 Adipose alternative TSS XM_039079395.1 0.02 0.02 1.8e-03 0.03 0.02 0.02 0.02 7.9e-04 5.6e-03 5.5e-03 3.9e-03
5 Adipose gene expression Mob3a 0.19 0.12 0.0e+00 0.19 0.18 0.18 0.18 2.4e-20 2.9e-19 1.5e-19 1.6e-19
6 PL gene expression Mob3a 0.07 0.04 3.7e-10 0.09 0.09 0.09 0.09 1.2e-09 2.3e-10 6.7e-10 1.0e-09
7 IL gene expression Mob3a 0.27 0.16 6.3e-05 0.12 0.09 0.05 0.09 1.0e-03 4.3e-03 2.3e-02 3.5e-03
8 BLA gene expression Mob3a 0.2 0.1 9.7e-13 0.22 0.23 0.23 0.24 6.5e-12 1.0e-12 1.9e-12 6.3e-13
9 Liver gene expression Mob3a 0.07 0.05 9.9e-10 0.06 0.06 0.05 0.06 2.2e-07 5.5e-07 3.1e-06 9.3e-07
10 pVTA gene expression Mob3a 0.84 0.1 3.8e-13 0.19 0.22 0.23 0.25 8.9e-09 7.6e-10 2.4e-10 3.5e-11

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.50.96.20.20.3-0.60.6-0.60.6-0.60.7-0.62.5
Area under the delay curve2.42.53.31.71.6-1.71.6-1.61.6-1.61.8-1.70.3
BMI with tail5.919.022.64.74.7-4.64.6-4.64.6-4.54.6-4.50.1
BMI without tail1.83.85.12.32.1-2.02.0-2.02.0-1.91.9-1.9-1.4
Body weight1.04.35.32.32.2-2.22.2-2.22.2-2.12.1-2.1-0.2
Weight adjusted by age0.30.31.70.60.5-0.30.4-0.40.3-0.40.3-0.3-1.3
Bone surface0.71.211.3-0.3-0.1-0.20.3-0.30.2-0.30.4-0.33.4
Bone volume0.71.110.7-0.3-0.1-0.20.3-0.30.2-0.30.4-0.33.3
Breakpoint value in progressive ratio session5.86.37.3-2.6-2.62.6-2.62.6-2.72.7-2.52.7-1.3
Number of licking bursts0.20.21.60.10.00.1-0.20.2-0.10.2-0.10.2-1.3
Context. condit. distance diff. score0.20.30.40.60.6-0.60.5-0.50.5-0.50.6-0.6-0.4
Locomotion velocity, session 10.40.41.6-0.7-0.60.5-0.50.5-0.50.5-0.60.41.3
Locomotion distance, session 10.60.76.9-0.2-0.0-0.10.1-0.10.2-0.10.2-0.22.6
Locomotion velocity, session 22.52.94.2-2.0-1.81.7-1.61.6-1.61.6-1.71.52.1
Locomotion distance, session 21.21.77.3-1.4-1.21.1-1.01.0-0.91.0-1.00.92.7
Locomotion velocity, session 35.96.87.7-2.8-2.82.7-2.72.7-2.82.7-2.72.7-0.9
Locomotion distance, session 30.00.00.30.0-0.0-0.0-0.10.1-0.00.10.00.0-0.5
Stereotopy head waving bouts, day 34.04.76.0-2.5-2.42.3-2.22.2-2.32.2-2.22.20.6
Stereotopy head waving duration, day 35.05.97.3-2.7-2.62.6-2.52.5-2.62.5-2.62.50.1
Locomotion velocity, session 70.60.70.8-0.8-0.90.9-0.80.8-0.90.8-0.90.8-0.7
Locomotion distance, session 70.20.21.90.30.2-0.10.1-0.10.1-0.10.0-0.1-1.4
Stereotopy head waving bouts, day 70.20.21.70.00.1-0.20.3-0.30.2-0.30.3-0.31.3
Stereotopy head waving duration, day 70.20.22.1-0.4-0.30.2-0.10.1-0.20.1-0.10.11.5
Locomotion velocity, session 80.50.54.1-0.6-0.50.4-0.30.3-0.30.3-0.30.32.0
Locomotion distance, session 80.10.21.1-0.3-0.30.2-0.20.2-0.20.2-0.20.21.0
Degree of sensitization distance0.30.30.40.60.6-0.60.6-0.60.6-0.60.5-0.60.1
Degree of sensitization stereotypy2.22.42.81.51.5-1.61.6-1.61.6-1.61.7-1.61.2
Conditioned locomotion1.01.21.61.31.2-1.11.1-1.11.0-1.11.0-1.0-1.2
Cocaine response after cond. corrected3.84.35.92.42.3-2.12.0-2.02.1-2.02.0-2.1-1.7
Cocaine response after cond. not corrected4.14.56.12.52.3-2.22.1-2.12.1-2.12.0-2.1-1.8
Cocaine response before conditioning0.30.40.5-0.7-0.70.7-0.60.6-0.70.6-0.70.70.1
Saline control response0.00.00.00.20.2-0.10.2-0.20.2-0.20.1-0.1-0.1
Bone: connectivity density0.71.13.80.60.7-0.91.0-1.00.9-1.01.0-1.01.9
Bone: cortical apparent density0.70.91.11.01.0-1.01.0-1.01.0-1.01.0-1.00.2
Bone: cortical area0.81.21.31.01.0-1.11.1-1.11.1-1.11.1-1.11.1
Bone: cortical porosity0.40.40.6-0.7-0.70.6-0.60.6-0.60.6-0.50.60.8
Bone: cortical porosity0.20.22.1-0.1-0.0-0.10.1-0.10.1-0.10.2-0.11.5
Bone: cortical thickness1.22.02.21.41.4-1.51.5-1.51.5-1.51.5-1.50.8
Bone: cortical thickness0.20.21.8-0.0-0.20.2-0.30.3-0.30.3-0.30.3-1.3
Bone: cortical tissue density0.50.60.70.80.8-0.80.8-0.80.8-0.80.8-0.80.1
Condit. Reinf. active minus inactive responses3.84.35.0-2.2-2.22.2-2.22.2-2.22.2-2.22.1-0.3
Condit. Reinf. active-inactive response ratio2.42.62.8-1.6-1.61.6-1.71.7-1.71.7-1.71.6-1.2
Condit. Reinf. active responses2.93.54.6-2.2-2.02.0-1.91.9-1.91.9-1.91.91.0
Condit. Reinf. inactive responses0.70.83.3-1.0-0.80.7-0.70.7-0.60.7-0.70.61.8
Incentive salience index mean1.72.02.7-1.6-1.61.5-1.51.5-1.41.5-1.41.40.8
Condit. Reinf. lever presses0.50.76.0-0.00.1-0.30.2-0.20.3-0.20.4-0.42.4
Condit. Reinf. active minus inactive responses2.83.43.8-1.8-1.81.9-1.91.9-1.91.9-1.91.9-1.4
Condit. Reinf. active-inactive response ratio0.50.51.8-0.4-0.40.6-0.70.7-0.60.7-0.60.6-1.3
Condit. Reinf. active responses2.33.23.6-1.8-1.91.8-1.91.9-1.91.9-1.81.8-1.1
Condit. Reinf. inactive responses1.01.21.5-1.1-1.21.1-1.11.1-1.21.1-1.11.1-0.4
Condit. Reinf. lever presses2.73.64.1-1.8-1.92.0-2.02.0-2.02.0-2.02.0-1.4
Condit. Reinf. lever reinforcers received1.92.72.9-1.5-1.71.7-1.71.7-1.71.7-1.61.7-1.4
Conditioned reinforcement - actives2.22.22.8-1.6-1.61.5-1.71.7-1.61.7-1.31.5-0.3
Conditioned reinforcement - inactives0.40.40.60.70.7-0.70.6-0.60.6-0.60.8-0.6-0.6
Conditioned locomotion7.28.710.5-3.1-3.13.1-3.23.2-3.13.2-2.82.9-0.7
Patch foraging indifference point 0 sec0.20.20.30.50.5-0.50.5-0.50.5-0.60.5-0.50.5
Patch foraging indifference point AUC1.01.11.4-1.1-1.11.1-1.21.2-1.11.2-1.01.1-0.4
Delay disc. indifference point, 0s delay8.79.611.02.93.0-3.23.1-3.13.2-3.23.3-3.22.8
Delay disc. indifference point, 16s delay0.20.20.20.40.4-0.40.4-0.40.4-0.40.4-0.50.0
Delay disc. indifference point, 2s delay6.26.98.42.72.7-2.82.7-2.72.7-2.82.9-2.71.2
Delay disc. indifference point, 24s delay0.50.50.70.90.8-0.70.8-0.80.8-0.70.6-0.8-0.4
Delay disc. indifference point, 4s delay1.41.51.91.21.1-1.31.3-1.31.2-1.21.4-1.30.6
Delay disc. indifference point, 8s delay1.01.01.41.21.1-1.11.0-1.01.0-1.01.1-1.1-0.6
Indifference point function ln k0.20.30.40.60.5-0.60.5-0.50.5-0.60.5-0.6-0.4
Indifference point function log k0.20.30.40.60.5-0.60.5-0.50.5-0.60.5-0.6-0.4
Patch foraging total patch changes 0 sec0.10.20.20.40.4-0.40.4-0.40.4-0.50.4-0.30.3
Patch foraging total patch changes 12 sec0.20.20.40.60.6-0.40.4-0.40.5-0.50.3-0.4-0.6
Patch foraging total patch changes 18 sec1.11.41.6-1.3-1.21.3-1.21.2-1.21.3-1.31.3-0.2
Patch foraging total patch changes 24 sec0.10.10.1-0.3-0.30.3-0.30.3-0.30.3-0.30.40.2
Patch foraging total patch changes 6 sec0.20.30.4-0.6-0.60.6-0.60.6-0.50.5-0.60.60.3
Patch foraging time to switch 0 sec2.13.36.01.51.6-1.71.9-1.91.8-1.91.7-1.72.5
Patch foraging water rate 0 sec0.50.85.8-0.1-0.30.4-0.70.7-0.50.6-0.30.4-2.4
Patch foraging water rate 12 sec0.71.04.01.21.0-0.80.7-0.70.8-0.70.8-0.8-2.0
Patch foraging water rate 18 sec1.31.811.5-0.4-0.60.8-1.01.0-0.90.9-0.90.8-3.4
Patch foraging water rate 24 sec0.71.09.50.50.3-0.1-0.20.2-0.00.10.0-0.0-3.1
Patch foraging water rate 6 sec1.01.56.0-0.7-0.91.0-1.11.1-1.01.2-1.11.0-2.4
Seeking ratio, delayed vs. immediate footshock3.94.55.5-2.3-2.32.2-2.22.2-2.22.2-2.22.10.1
Distance traveled before self-admin0.40.50.70.70.7-0.70.5-0.50.7-0.60.9-0.80.8
Distance traveled after self-admin0.60.71.0-0.9-0.90.8-1.01.0-0.80.9-0.70.70.2
Extensor digitorum longus weight3.915.319.34.44.3-4.23.9-3.94.1-3.94.2-4.1-0.9
Bone: elastic displacement0.20.20.3-0.5-0.50.5-0.50.5-0.50.5-0.50.50.1
Bone: elastic work0.20.30.40.50.5-0.60.6-0.60.6-0.60.5-0.60.3
Bone: endosteal estimation0.20.50.60.70.7-0.80.8-0.80.7-0.80.8-0.80.5
Bone: endosteal perimeter0.10.30.4-0.6-0.60.5-0.40.4-0.50.4-0.50.40.6
Epididymis fat weight0.20.50.7-0.7-0.70.8-0.80.8-0.70.7-0.80.7-0.6
Delta time in closed arm before/after self-admin0.70.64.70.70.6-0.40.3-0.30.4-0.30.4-0.3-2.2
Delta time in open arm before/after self-admin1.31.31.61.11.2-1.11.2-1.21.2-1.21.0-1.20.8
Diff in mean of infusions in LGA sessions1.71.82.2-1.5-1.41.4-1.41.4-1.41.4-1.51.5-0.3
Delay discount exponential model param2.12.32.9-1.6-1.51.6-1.51.5-1.51.5-1.71.6-0.2
Extinction: sum of active levers before priming1.71.72.0-1.2-1.21.3-1.41.4-1.31.4-1.11.4-1.3
Active lever presses in extinction session 62.72.63.2-1.8-1.81.7-1.81.8-1.71.8-1.51.7-0.0
Bone: final force1.52.32.61.51.5-1.61.6-1.61.6-1.61.6-1.60.9
Bone: final moment1.11.92.11.31.3-1.41.4-1.41.4-1.41.4-1.40.9
Food consumed during 24 hour testing period0.50.60.90.80.8-0.80.7-0.70.7-0.70.9-0.7-0.3
Glucose1.21.72.21.51.4-1.41.3-1.31.4-1.31.4-1.4-0.1
Heart weight0.50.71.1-0.7-0.70.8-0.80.8-0.80.8-0.80.8-1.0
Delay discount hyperbolic model param3.03.24.1-1.9-1.81.9-1.91.9-1.81.8-2.01.9-0.3
Intermittent access intake day 1-15 change7.17.08.0-2.7-2.82.8-2.82.8-2.82.8-2.72.8-1.0
Intermittent access intake escalation7.77.68.6-2.7-2.82.8-2.92.9-2.82.9-2.72.9-1.9
Intermittent access intake escalation 29.39.110.2-2.9-3.03.1-3.23.2-3.13.2-3.13.1-2.0
Intermitt. access day 1 inactive lever presses0.60.61.5-0.5-0.60.7-0.90.9-0.70.9-0.50.6-1.2
Intermitt. access day 15 inactive lever presses0.50.60.7-0.8-0.80.8-0.80.8-0.80.8-0.80.7-0.6
Intermitt. access escalation Index0.60.51.60.50.5-0.60.7-0.70.6-0.70.6-0.51.3
Intermittent access day 1 total infusions0.10.10.10.20.2-0.30.3-0.30.2-0.30.4-0.40.2
Intermittent access day 15 total infusions2.22.52.8-1.6-1.61.6-1.71.7-1.71.7-1.51.6-1.0
Intermittent access terminal intake (last 3 days)1.11.21.5-1.1-1.21.2-1.21.2-1.21.2-1.01.1-0.6
Intermittent access total infusions0.20.30.3-0.5-0.50.5-0.60.6-0.60.6-0.40.5-0.5
Intermittent access day 1 locomotion0.30.40.4-0.6-0.70.6-0.60.6-0.70.6-0.60.6-0.3
Intermittent access day 15 total locomotion3.63.94.6-2.1-2.12.1-2.22.2-2.12.2-1.91.9-0.6
Intermittent access total locomotion0.91.11.4-1.1-1.11.1-1.21.2-1.11.2-0.81.0-0.1
Intermittent access standard deviation3.33.54.3-1.8-1.92.0-2.12.1-2.02.1-1.71.8-1.2
Left kidney weight0.00.10.7-0.2-0.10.1-0.00.0-0.10.1-0.10.00.8
Right kidney weight1.33.54.1-2.0-2.02.0-2.02.0-2.01.9-2.01.9-0.1
Cocaine induced anxiety0.50.51.8-0.8-0.70.6-0.60.6-0.60.6-0.40.61.3
Post-drug Anxiety0.30.31.8-0.6-0.50.4-0.30.3-0.30.3-0.50.31.3
Baseline Anxiety0.20.21.1-0.3-0.30.4-0.30.3-0.40.3-0.60.3-1.1
Tail length3.29.710.8-3.2-3.23.2-3.33.3-3.23.3-3.33.2-1.4
Length with tail1.76.17.2-2.7-2.72.6-2.62.6-2.62.6-2.62.6-0.0
Length without tail0.10.22.0-0.3-0.20.10.0-0.0-0.00.0-0.1-0.01.4
Times rat made contact with spout0.10.20.70.40.4-0.30.3-0.30.3-0.30.3-0.3-0.8
Lifetime Intake0.10.10.1-0.3-0.30.3-0.30.3-0.30.3-0.10.2-0.2
Liver weight, left2.13.44.22.02.0-1.91.9-1.92.0-1.91.8-1.9-0.0
Liver weight, right1.82.93.31.81.8-1.81.8-1.81.8-1.81.8-1.80.8
Locomotor activity2.64.15.3-2.3-2.22.1-2.12.1-2.12.1-2.02.11.0
Locomotor testing distance1.72.83.4-1.9-1.81.8-1.71.7-1.71.7-1.71.70.5
Locomotor testing rearing0.10.20.9-0.2-0.30.3-0.30.3-0.30.3-0.40.3-1.0
Locomotion in novel chamber0.40.50.8-0.6-0.60.7-0.80.8-0.70.9-0.70.7-0.5
Locomotion in novel chamber post-restriction0.81.01.1-1.0-1.01.0-1.01.0-1.11.0-1.01.0-0.9
Fecal boli incidents, locomotor time 11.31.41.91.41.4-1.21.2-1.21.3-1.21.2-1.20.1
Change in fecal boli incidents, locomotor task0.10.10.2-0.4-0.40.3-0.30.3-0.40.3-0.30.30.2
Time >=10cm from walls, locomotor time 10.60.61.80.60.7-0.70.6-0.60.8-0.70.7-0.71.4
Bouts of movement, locomotor time 10.20.20.3-0.4-0.50.5-0.50.5-0.50.5-0.50.5-0.4
Total resting periods, locomotor time 10.20.30.3-0.5-0.50.5-0.60.6-0.50.5-0.50.5-0.3
Rest time, locomotor task time 10.20.20.3-0.5-0.50.4-0.50.5-0.40.4-0.40.40.3
Distance moved, locomotor task time 10.70.81.30.70.8-0.80.9-0.90.9-0.80.8-0.81.2
Vertical activity count, locomotor time 10.10.10.80.30.2-0.20.2-0.20.2-0.20.2-0.2-0.9
Time >=10cm from walls, locomotor time 20.80.91.41.21.1-1.00.8-0.81.0-0.90.9-0.9-0.4
Bouts of movement, locomotor time 20.30.31.4-0.6-0.50.4-0.40.4-0.40.4-0.40.41.2
Total resting periods, locomotor time 20.30.31.6-0.6-0.50.4-0.40.4-0.40.3-0.30.31.2
Rest time, locomotor task time 20.40.40.6-0.8-0.70.7-0.70.7-0.60.6-0.60.60.7
Distance moved, locomotor task time 20.50.60.80.90.9-0.80.8-0.80.8-0.80.8-0.8-0.3
Vertical activity count, locomotor time 20.50.51.10.80.8-0.70.5-0.50.6-0.60.6-0.6-1.1
Light reinforcement 15.19.311.5-3.4-3.33.2-3.13.1-3.23.2-3.23.20.3
Light reinforcement 21.72.22.9-1.7-1.61.6-1.51.5-1.61.5-1.61.50.4
Bone: marrow area0.30.60.70.70.7-0.80.8-0.80.7-0.80.8-0.80.5
Bone: maximum diameter0.40.81.1-1.0-1.00.8-0.80.8-0.90.8-0.80.81.0
Bone: maximum force1.32.32.61.61.5-1.61.6-1.61.6-1.61.5-1.60.6
Bone: maximum moment1.11.92.11.41.4-1.41.5-1.51.4-1.51.4-1.50.6
Mean time between licks in bursts4.36.06.9-2.5-2.52.6-2.62.6-2.62.6-2.62.6-1.0
Mean num. licks in bursts0.10.10.20.20.2-0.30.3-0.30.3-0.30.3-0.30.4
Cd content in liver0.20.20.30.50.5-0.50.5-0.50.5-0.50.5-0.50.4
Co content in liver0.60.70.9-0.8-0.90.9-0.90.9-0.90.9-0.90.9-0.4
Cu content in liver0.30.41.60.40.4-0.50.5-0.50.5-0.50.5-0.61.3
Fe content in liver0.10.10.3-0.2-0.20.3-0.20.2-0.20.2-0.30.3-0.6
K content in liver0.30.32.20.10.2-0.30.2-0.20.3-0.20.3-0.31.5
Mg content in liver0.30.32.30.10.2-0.30.2-0.20.3-0.20.3-0.41.5
Mn content in liver0.70.74.5-0.9-0.80.6-0.50.5-0.50.5-0.50.52.1
Na content in liver1.41.52.61.01.1-1.21.2-1.21.2-1.21.2-1.21.6
Rb content in liver0.81.02.50.70.8-0.90.9-0.90.9-0.91.0-0.91.6
Se content in liver0.10.10.2-0.4-0.40.4-0.40.4-0.40.4-0.30.40.2
Sr content in liver0.20.21.4-0.1-0.20.2-0.30.3-0.30.3-0.20.3-1.2
Zn content in liver2.93.24.7-1.5-1.61.7-1.91.9-1.81.9-1.61.8-2.2
Bone: minimum diameter0.00.10.40.10.1-0.20.3-0.30.2-0.30.3-0.30.6
Time in familiar zone, hab. session 12.42.33.0-1.5-1.51.6-1.51.5-1.61.5-1.71.6-1.2
Time in novel zone, hab. session 11.41.41.81.01.1-1.21.1-1.11.2-1.11.3-1.21.3
Total zone transitions, hab. session 10.71.03.5-1.1-0.90.8-0.80.8-0.70.8-0.80.71.9
Total locomotion distance, hab. session 10.81.16.2-1.1-0.90.8-0.60.6-0.70.6-0.80.62.5
Locomotion velocity, hab. session 11.11.55.3-1.4-1.21.1-1.01.0-1.01.0-1.11.02.3
Time in familiar zone, hab. session 26.97.17.9-2.7-2.72.8-2.72.7-2.82.7-2.82.8-1.8
Time in novel zone, hab. session 25.35.25.92.32.3-2.42.4-2.42.4-2.42.4-2.41.5
Total zone transitions, hab. session 21.11.59.40.40.6-0.70.8-0.80.9-0.80.8-0.83.1
Total locomotion distance, hab. session 20.71.04.2-1.0-0.90.8-0.70.7-0.70.7-0.80.72.1
Locomotion velocity, hab. session 20.81.16.7-1.0-0.80.7-0.60.6-0.60.6-0.70.62.6
Novel to familiar place preference ratio4.95.15.72.22.2-2.32.3-2.32.3-2.32.4-2.31.9
Novelty place preference3.13.23.61.71.7-1.91.8-1.81.8-1.81.9-1.91.7
Time in novel zone, NPP test3.43.54.01.81.8-2.01.9-1.91.9-1.92.0-2.01.6
Total zone transitions, NPP test0.40.65.00.00.2-0.20.3-0.30.4-0.30.2-0.32.2
Total locomotion distance, NPP test0.50.64.90.20.3-0.40.5-0.50.5-0.50.4-0.52.2
Locomotion velocity, NPP test0.30.54.7-0.10.0-0.10.2-0.20.2-0.20.1-0.22.2
Intraocular pressure0.40.64.0-0.2-0.30.4-0.40.4-0.40.5-0.50.5-2.0
Delta distance traveled before/after self-admin1.51.62.0-1.4-1.41.3-1.31.3-1.41.3-1.41.4-0.2
Delta ambulatory time before/after self-admin1.51.62.1-1.4-1.41.3-1.31.3-1.41.3-1.31.40.0
Parametrial fat weight0.50.91.1-0.9-1.01.0-1.01.0-1.01.0-0.91.0-0.8
Pavlov. Cond. lever latency0.30.32.3-0.1-0.20.3-0.40.4-0.30.4-0.40.4-1.5
Pavlov. Cond. magazine entry latency2.83.64.2-2.0-2.02.0-2.02.0-2.02.0-2.02.0-0.5
Pavlov. Cond. change in total contacts0.00.00.1-0.2-0.20.2-0.20.2-0.20.2-0.10.20.3
Pavlov. Cond. index score0.30.30.7-0.7-0.60.5-0.50.5-0.50.5-0.50.50.8
Pavlov. Cond. latency score0.30.31.6-0.6-0.50.4-0.40.4-0.40.4-0.30.41.3
Pavlov. Cond. lever contacts0.30.32.9-0.10.0-0.20.2-0.20.2-0.20.4-0.21.7
Pavlov. Cond. magazine entry number0.60.70.91.00.9-0.90.9-0.90.9-0.90.9-0.9-0.0
Pavlov. Cond. intertrial magazine entries0.30.41.2-0.4-0.50.5-0.60.6-0.60.6-0.60.6-1.1
Pavlov. Cond. lever-magazine prob. diff.0.50.60.9-1.0-0.90.8-0.80.8-0.80.8-0.70.80.7
Pavlov. Cond. response bias0.91.11.4-1.2-1.21.1-1.11.1-1.11.1-1.11.10.1
Pavlov. Cond. lever latency0.81.11.21.01.1-1.11.0-1.01.1-1.01.1-1.10.7
Pavlov. Cond. magazine entry latency0.40.50.6-0.7-0.80.7-0.70.7-0.70.7-0.70.7-0.4
Pavlov. Cond. change in total contacts0.81.11.3-1.0-1.11.1-1.11.1-1.11.1-1.11.1-0.8
Pavlov. Cond. index score0.91.21.4-1.1-1.11.1-1.11.1-1.11.1-1.21.1-0.8
Pavlov. Cond. latency score0.81.01.1-1.0-1.11.0-1.01.0-1.01.0-1.11.0-0.5
Pavlov. Cond. lever contacts0.91.21.3-1.0-1.11.1-1.11.1-1.11.1-1.11.1-1.1
Pavlov. Cond. magazine entry number0.70.81.00.91.0-0.91.0-1.01.0-1.01.0-0.90.5
Pavlov. Cond. intertrial magazine entries0.20.20.50.60.5-0.50.4-0.40.4-0.40.4-0.4-0.7
Pavlov. Cond. lever-magazine prob. diff.0.91.11.3-1.1-1.11.1-1.11.1-1.11.1-1.21.1-0.6
Pavlov. Cond. response bias2.02.73.0-1.6-1.71.7-1.71.7-1.71.7-1.71.7-1.3
Time in closed arm before self-admin1.41.53.60.91.0-1.11.3-1.31.2-1.21.2-1.11.9
Time in closed arm after self-admin0.00.00.1-0.1-0.10.1-0.10.1-0.10.0-0.10.3-0.2
Time in open arm before self-admin1.01.11.5-1.0-1.11.1-1.21.2-1.11.2-0.91.0-0.8
Time in open arm after self-admin0.60.71.00.90.9-0.80.8-0.80.9-0.80.8-1.0-0.0
Bone: periosteal estimation0.51.11.30.90.9-1.01.1-1.11.0-1.11.1-1.11.2
Bone: periosteal perimeter0.10.11.0-0.2-0.20.00.0-0.0-0.0-0.00.0-0.01.0
Bone: post-yield work0.50.70.80.90.9-0.80.8-0.80.8-0.80.8-0.8-0.3
Progressive ratio test 1 active lever presses0.10.10.30.30.2-0.20.2-0.20.2-0.20.3-0.2-0.6
Progressive ratio test 1 breakpoint0.10.10.20.40.3-0.40.3-0.30.3-0.30.4-0.3-0.5
Progressive ratio test 1 inactive lever presses0.00.00.0-0.1-0.10.0-0.10.1-0.10.10.10.10.1
Progressive ratio test 2 active lever presses0.40.40.9-0.5-0.50.6-0.70.7-0.60.7-0.40.5-1.0
Progressive ratio test 2 breakpoint0.30.30.5-0.5-0.60.6-0.70.7-0.60.7-0.40.5-0.5
Progressive ratio test 2 inactive lever presses0.00.00.1-0.2-0.20.2-0.20.2-0.20.20.00.10.2
Incentive Sensitization - Responses0.40.51.0-0.5-0.50.6-0.80.8-0.60.8-0.40.6-1.0
Incentive Sensitization - Breakpoint0.50.50.8-0.5-0.60.6-0.80.8-0.60.8-0.50.6-0.9
Sum of active levers in priming session hrs 5-60.00.00.0-0.0-0.00.0-0.10.10.00.10.10.00.2
Progressive ratio0.10.10.30.40.5-0.40.4-0.40.4-0.40.3-0.4-0.1
Food seeking constrained by brief footshock0.10.10.4-0.4-0.30.3-0.30.3-0.30.3-0.30.30.6
Seeking ratio, punishment vs. effort0.10.10.3-0.5-0.40.3-0.30.3-0.40.3-0.30.40.5
Retroperitoneal fat weight0.30.91.01.01.0-0.91.0-1.01.0-1.00.9-1.0-0.2
Reaction time number correct0.50.73.40.80.7-0.60.5-0.50.5-0.50.6-0.5-1.8
Reaction time mean minus median0.81.01.2-0.9-1.01.0-1.11.1-1.01.1-1.00.9-0.8
Reaction time mean minus median AUC0.10.10.60.10.1-0.20.2-0.20.2-0.10.1-0.30.8
Reaction time num false alarms0.20.32.50.30.1-0.20.0-0.00.0-0.00.2-0.1-1.6
Reaction time num false alarms AUC0.30.43.20.40.2-0.20.1-0.10.1-0.10.2-0.1-1.8
Reaction time trials correct on left0.50.73.40.80.7-0.60.5-0.50.5-0.50.6-0.5-1.8
Reaction time trials on left0.40.63.00.80.7-0.60.5-0.50.5-0.50.7-0.6-1.7
Reaction time mean0.00.00.20.10.1-0.10.2-0.20.2-0.20.0-0.20.5
Reaction time mean AUC0.10.10.30.20.2-0.20.3-0.30.3-0.30.1-0.30.5
Median of all reaction times0.40.50.60.60.6-0.70.7-0.70.7-0.80.6-0.70.8
Reaction time omissions0.20.30.4-0.6-0.60.5-0.60.6-0.50.6-0.40.50.4
Reaction time false alarm rate0.00.00.10.10.1-0.10.1-0.10.1-0.10.2-0.1-0.4
Reaction time premature initiation rate1.31.82.1-1.3-1.31.4-1.41.4-1.41.3-1.41.4-1.0
Reaction time premature initiations1.21.74.3-0.9-1.11.2-1.31.3-1.21.1-1.21.2-2.1
Std. dev. reaction times0.20.20.3-0.5-0.50.5-0.50.5-0.50.6-0.50.4-0.2
Reaction time trials completed0.40.63.00.80.7-0.60.5-0.50.5-0.50.7-0.6-1.7
Reaction time trials AUC0.50.74.10.80.6-0.50.4-0.40.4-0.40.6-0.4-2.0
Run reversals in cocaine runway, females0.30.30.4-0.6-0.60.5-0.50.5-0.50.5-0.40.40.1
Run reversals in cocaine runway, males1.01.01.3-1.2-1.11.0-1.01.0-1.01.0-1.01.00.4
Latency to leave start box in cocaine runway0.70.81.5-1.0-0.90.8-0.90.9-0.80.9-0.70.61.2
Latency to leave start box in cocaine runway, F0.50.54.40.10.2-0.20.2-0.20.4-0.20.4-0.62.1
Latency to leave start box in cocaine runway, M3.63.43.8-1.7-1.81.9-1.91.9-1.91.9-1.91.9-1.5
Std. dev. time between licks in bursts0.50.70.9-0.9-0.90.9-0.80.8-0.90.8-0.90.80.2
Total sessions with >9 infusions0.00.10.20.10.1-0.20.1-0.10.1-0.10.4-0.20.5
Short access day 1 total inactive lever presses0.00.00.1-0.3-0.20.1-0.20.2-0.20.20.00.30.2
Short access day 10 total inactive lever presses0.10.10.2-0.2-0.20.3-0.40.4-0.30.4-0.10.3-0.4
Short access day 1 total infusions0.10.10.8-0.3-0.30.1-0.10.1-0.20.10.00.20.9
Short access day 10 total infusions0.00.10.3-0.1-0.20.1-0.20.2-0.20.20.00.1-0.6
Short access total infusions0.00.00.10.00.0-0.10.0-0.00.0-0.00.2-0.10.2
Short access day 1 locomotion0.70.71.0-1.0-1.00.9-0.90.9-0.90.9-0.60.80.4
Short access day 10 total locomotion4.34.85.7-2.3-2.32.2-2.42.4-2.32.4-2.02.2-0.9
Short access total locomotion0.80.81.1-1.0-1.00.9-1.01.0-1.01.0-0.60.9-0.0
One hour access (0.3 mA shock)0.20.20.40.40.4-0.50.4-0.40.4-0.40.6-0.6-0.1
Compulsive drug intake1.41.41.61.11.2-1.21.2-1.21.2-1.21.3-1.20.9
One hour access (shock baseline)0.20.20.8-0.3-0.40.3-0.40.4-0.40.4-0.20.3-0.9
Social response proportion0.50.51.0-0.8-0.70.7-0.60.6-0.60.6-0.80.71.0
Social responses5.87.59.2-3.0-3.02.9-2.82.8-2.82.8-2.92.80.3
Social time0.50.70.90.80.9-0.80.9-0.90.9-0.90.7-0.80.6
Soleus weight8.524.929.05.45.3-5.35.2-5.25.2-5.25.2-5.20.4
Bone: stiffness3.14.95.52.32.3-2.32.3-2.32.3-2.32.3-2.30.7
Tibialis anterior weight1.13.74.92.12.1-2.11.9-1.92.0-1.92.2-2.10.0
Time to tail flick, vehicle, before self-admin0.30.31.2-0.6-0.50.5-0.40.4-0.40.5-0.40.41.1
Time to tail flick, vehicle, after self-admin0.40.42.1-0.3-0.40.5-0.40.4-0.50.4-0.80.6-1.5
Time to tail flick, test, before self-admin0.20.21.3-0.4-0.30.2-0.00.0-0.20.1-0.20.31.1
Time to tail flick, test, after self-admin0.10.10.3-0.4-0.40.4-0.30.3-0.30.3-0.50.40.5
Delta time to tail flick, vehicle, before/after SA0.40.42.90.60.5-0.30.4-0.40.3-0.40.1-0.2-1.7
Delta time to tail flick, test, before/after SA0.30.30.9-0.4-0.40.4-0.50.5-0.50.5-0.50.4-0.9
Tibia length0.92.63.4-1.7-1.71.7-1.71.7-1.71.7-1.81.7-0.5
Ambulatory time before self-admin0.30.40.60.60.6-0.60.4-0.40.6-0.50.8-0.70.6
Ambulatory time after self-admin0.30.40.6-0.7-0.60.6-0.80.8-0.60.7-0.40.50.3
Bone: tissue strength1.71.71.91.31.4-1.31.4-1.41.4-1.41.3-1.40.7
Total heroin consumption1.82.22.5-1.6-1.61.5-1.51.5-1.51.6-1.51.6-0.3
Bone: trabecular number0.40.62.0-0.9-0.80.6-0.60.6-0.60.6-0.50.61.4
Bone: trabecular spacing0.50.76.30.60.4-0.20.1-0.10.2-0.10.0-0.1-2.5
Bone: trabecular thickness1.21.511.20.20.3-0.60.7-0.70.7-0.70.7-0.73.3
Bone: trabecular tissue density1.31.82.31.51.5-1.41.4-1.41.4-1.41.3-1.4-0.2
Water consumed over 24 hours0.80.91.10.90.9-1.01.0-1.01.0-1.01.0-1.00.9
Number of responses in last shaping day0.10.10.2-0.4-0.40.3-0.40.4-0.40.4-0.10.3-0.2