Hub : Genes

Micb

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression Micb 0.37 0.24 1.2e-06 0.15 0.22 0.18 0.24 2.0e-04 4.7e-06 3.9e-05 2.4e-06
2 BLA mRNA stability Micb 0.07 0.07 7.1e-03 0.02 0.01 0 0.01 1.8e-02 9.5e-02 2.3e-01 1.0e-01
3 Brain gene expression Micb 0.22 0.11 0.0e+00 0.25 0.28 0.27 0.27 1.5e-23 3.0e-26 2.3e-25 2.6e-25
4 Eye gene expression Micb 0.51 0.26 3.3e-04 0.06 0.07 0.1 0.08 3.8e-02 3.7e-02 1.5e-02 2.6e-02
5 LHb mRNA stability Micb 0.54 0.26 2.4e-10 0.31 0.43 0.34 0.4 3.2e-08 1.6e-11 6.4e-09 1.1e-10
6 Brain mRNA stability Micb 0.15 0.09 0.0e+00 0.17 0.18 0.17 0.17 1.0e-15 1.1e-16 2.0e-15 2.7e-15
7 PL intron excision ratio chr1_87624700_87638482 0.07 0.05 5.3e-09 0.08 0.08 0.08 0.08 9.5e-09 1.8e-09 2.4e-09 5.4e-09
8 NAcc intron excision ratio chr1_87624700_87638482 0.2 0.13 0.0e+00 0.13 0.13 0.13 0.13 6.3e-19 1.0e-18 4.6e-19 5.0e-19
9 Adipose intron excision ratio chr1_87640903_87642210 0.04 0.04 7.6e-05 0.03 0.03 0.03 0.03 2.4e-04 1.2e-04 3.5e-04 3.7e-04
10 NAcc intron excision ratio chr1_87640903_87642210 0.03 0.02 2.2e-04 0.02 0.02 0.02 0.02 2.1e-04 1.5e-04 8.9e-04 2.0e-04
11 PL intron excision ratio chr1_87623943_87638482 0.07 0.05 2.3e-09 0.09 0.09 0.08 0.08 9.8e-10 8.2e-10 1.7e-09 2.6e-09
12 NAcc intron excision ratio chr1_87623943_87638482 0.19 0.13 0.0e+00 0.12 0.12 0.13 0.12 2.4e-18 3.7e-18 1.6e-18 2.1e-18
13 IC intron excision ratio chr1_87623943_87638482 0.15 0.11 4.0e-04 0.07 0.06 0.06 0.06 4.5e-04 1.9e-03 1.3e-03 1.3e-03
14 IC intron excision ratio chr1_87624700_87638482 0.15 0.11 3.9e-04 0.08 0.06 0.06 0.06 4.3e-04 1.8e-03 1.2e-03 1.3e-03
15 Liver gene expression Micb 0.12 0.09 5.3e-14 0.11 0.12 0.11 0.11 2.5e-12 4.6e-13 1.6e-12 2.0e-12
16 pVTA gene expression Micb 0.08 0.06 4.0e-05 0.04 0.04 0.03 0.04 3.1e-04 4.6e-04 2.2e-03 4.4e-04
17 IL gene expression Micb 0.16 0.17 8.8e-03 0.05 0.05 0.01 0.04 2.9e-02 2.3e-02 1.4e-01 3.8e-02
18 NAcc mRNA stability Micb 0.12 0.07 0.0e+00 0.12 0.12 0.12 0.12 2.2e-18 7.7e-18 2.3e-17 4.8e-18
19 Adipose mRNA stability Micb 0.77 0.06 0.0e+00 0.65 0.65 0.65 0.65 1.2e-94 3.4e-95 6.9e-96 9.4e-96
20 NAcc gene expression Micb 0.3 0.12 0.0e+00 0.33 0.32 0.32 0.32 6.1e-51 2.5e-50 1.3e-50 1.5e-50
21 PL gene expression Micb 0.13 0.09 2.8e-16 0.15 0.15 0.15 0.15 2.0e-16 5.0e-16 5.2e-16 7.0e-16
22 Adipose gene expression Micb 0.79 0.04 0.0e+00 0.7 0.7 0.7 0.7 2.3e-107 3.9e-110 3.6e-109 3.0e-108
23 PL mRNA stability Micb 0.02 0.02 6.2e-03 0.01 0.01 0.02 0.01 4.6e-02 1.5e-02 2.6e-03 7.1e-02
24 Brain intron excision ratio chr1_87624700_87638482 0.09 0.07 2.9e-10 0.1 0.1 0.1 0.1 2.6e-09 6.9e-10 5.3e-10 2.0e-09
25 Brain intron excision ratio chr1_87623943_87638482 0.1 0.07 4.3e-11 0.11 0.11 0.12 0.11 2.0e-10 1.2e-10 6.4e-11 3.1e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density0.00.00.30.3-0.10.10.00.10.1-0.1-0.10.00.00.10.1-0.00.0-0.0-0.1-0.0-0.10.00.20.1-0.2-0.4-0.40.5
Area under the delay curve1.01.52.3-0.90.8-1.21.3-1.2-1.21.2-1.3-1.2-1.2-1.21.31.3-1.3-1.31.4-1.31.11.41.51.3-1.50.9-0.70.8
BMI with tail0.62.34.22.0-2.01.7-1.51.71.7-1.61.51.61.61.6-1.5-1.51.51.5-1.61.5-1.6-1.3-1.2-1.40.8-0.91.1-0.8
BMI without tail0.52.95.92.4-2.41.9-1.61.91.9-1.81.51.81.81.8-1.5-1.71.71.6-1.61.7-1.9-1.5-1.3-1.50.9-1.51.4-0.9
Body weight1.46.19.63.1-3.12.7-2.42.72.6-2.62.42.62.62.6-2.3-2.62.62.4-2.42.4-2.7-2.2-2.1-2.21.6-1.92.3-1.8
Weight adjusted by age0.00.10.90.3-0.30.20.00.10.1-0.10.00.10.10.1-0.00.1-0.10.10.00.1-0.1-0.00.0-0.0-0.2-0.3-0.70.9
Bone surface0.20.51.31.2-0.90.8-0.60.80.8-0.80.60.70.70.8-0.6-0.60.60.7-0.60.7-0.7-0.6-0.6-0.50.3-1.10.30.0
Bone volume0.20.30.90.8-0.70.6-0.60.60.6-0.60.50.60.60.6-0.5-0.50.50.6-0.60.5-0.6-0.5-0.4-0.40.3-0.9-0.10.3
Breakpoint value in progressive ratio session1.42.53.7-1.91.9-1.81.5-1.7-1.81.7-1.5-1.7-1.7-1.71.61.3-1.3-1.71.5-1.71.31.61.51.6-1.31.6-0.90.5
Number of licking bursts1.44.24.62.0-1.92.1-2.12.12.1-2.12.12.12.12.1-2.1-2.02.02.1-2.12.1-2.0-2.1-2.1-2.12.1-1.82.0-1.8
Context. condit. distance diff. score0.10.10.30.2-0.10.3-0.30.30.3-0.30.30.30.30.3-0.3-0.30.30.3-0.30.3-0.3-0.4-0.3-0.40.6-0.30.4-0.4
Locomotion velocity, session 10.10.10.5-0.70.4-0.40.1-0.4-0.30.3-0.2-0.3-0.3-0.30.20.2-0.2-0.30.1-0.30.20.10.30.10.20.0-0.60.6
Locomotion distance, session 10.00.00.2-0.20.0-0.1-0.0-0.1-0.10.00.0-0.0-0.0-0.0-0.10.1-0.1-0.0-0.0-0.00.1-0.0-0.10.00.1-0.1-0.40.4
Locomotion velocity, session 21.41.62.01.4-1.41.4-1.31.41.4-1.41.31.41.41.4-1.3-1.31.31.3-1.21.3-1.3-1.3-1.2-1.41.2-1.30.5-0.2
Locomotion distance, session 20.20.30.80.8-0.80.6-0.50.60.6-0.60.50.60.60.6-0.5-0.40.40.5-0.50.5-0.4-0.5-0.5-0.40.4-0.9-0.00.3
Locomotion velocity, session 30.20.30.50.6-0.70.6-0.50.60.6-0.50.50.50.60.5-0.5-0.50.50.5-0.30.5-0.5-0.5-0.4-0.50.3-0.70.00.1
Locomotion distance, session 30.91.02.4-0.80.7-0.91.0-0.9-0.90.9-1.0-0.9-0.9-0.91.01.0-1.0-0.91.1-0.91.01.00.91.0-1.20.5-1.51.5
Stereotopy head waving bouts, day 31.21.42.40.9-1.01.1-1.31.11.1-1.11.21.11.11.1-1.2-1.11.11.2-1.21.1-1.1-1.2-1.1-1.21.3-1.01.5-1.4
Stereotopy head waving duration, day 31.01.32.00.8-0.81.1-1.31.01.1-1.11.21.11.11.1-1.2-1.01.01.1-1.21.1-1.0-1.2-1.2-1.21.4-0.81.3-1.3
Locomotion velocity, session 70.20.30.5-0.70.6-0.60.5-0.6-0.60.6-0.4-0.5-0.5-0.60.40.4-0.4-0.50.6-0.50.40.50.40.5-0.50.3-0.50.4
Locomotion distance, session 70.10.10.60.3-0.30.20.00.20.1-0.10.10.10.10.1-0.1-0.10.10.1-0.00.1-0.10.0-0.20.1-0.2-0.20.8-0.8
Stereotopy head waving bouts, day 71.01.12.20.6-0.61.0-1.31.01.0-1.01.11.01.01.0-1.1-1.11.11.1-1.21.1-1.1-1.3-1.1-1.31.5-1.20.7-0.6
Stereotopy head waving duration, day 70.81.01.90.7-0.70.9-1.20.91.0-1.01.01.01.01.0-1.0-1.01.01.0-1.01.0-1.0-1.1-1.0-1.21.3-1.40.4-0.1
Locomotion velocity, session 80.00.00.1-0.1-0.0-0.10.1-0.1-0.10.1-0.1-0.1-0.1-0.10.10.2-0.2-0.10.1-0.00.20.00.10.00.0-0.3-0.20.3
Locomotion distance, session 80.00.00.10.2-0.20.00.00.00.0-0.0-0.00.00.00.00.00.0-0.00.00.00.00.0-0.00.0-0.00.0-0.3-0.00.2
Degree of sensitization distance0.80.94.20.9-0.80.8-0.70.80.8-0.80.80.80.80.8-0.8-0.80.80.8-0.90.8-0.8-0.7-0.8-0.60.8-0.52.0-2.1
Degree of sensitization stereotypy1.01.11.90.7-0.71.0-1.31.01.0-1.01.11.11.01.0-1.1-1.21.21.1-1.21.1-1.2-1.2-1.1-1.31.4-1.40.20.1
Conditioned locomotion0.10.10.2-0.30.3-0.30.3-0.3-0.30.3-0.2-0.3-0.3-0.30.20.2-0.2-0.30.3-0.20.20.30.30.3-0.30.2-0.50.5
Cocaine response after cond. corrected0.40.60.80.6-0.60.7-0.80.70.7-0.70.80.70.70.7-0.8-0.90.90.8-0.80.8-0.8-0.8-0.9-0.80.9-0.90.5-0.4
Cocaine response after cond. not corrected1.01.51.91.1-1.11.2-1.31.21.2-1.21.31.21.21.2-1.3-1.41.41.2-1.31.2-1.3-1.3-1.3-1.31.3-1.20.9-0.8
Cocaine response before conditioning1.62.02.41.6-1.41.4-1.51.41.4-1.41.41.41.41.4-1.4-1.51.51.4-1.41.4-1.5-1.4-1.3-1.31.2-1.01.4-1.3
Saline control response1.82.53.41.3-1.51.6-1.81.61.6-1.61.71.61.61.6-1.7-1.51.51.7-1.71.7-1.5-1.7-1.7-1.71.7-1.80.10.3
Bone: connectivity density0.10.10.30.4-0.1-0.00.4-0.0-0.10.1-0.3-0.1-0.1-0.10.30.2-0.2-0.20.3-0.20.00.30.30.3-0.6-0.5-0.50.6
Bone: cortical apparent density0.00.10.2-0.10.3-0.30.3-0.3-0.30.3-0.4-0.2-0.3-0.30.40.2-0.2-0.30.2-0.30.20.30.40.1-0.30.4-0.10.0
Bone: cortical area1.52.43.11.8-1.61.7-1.61.61.6-1.61.61.61.61.6-1.6-1.51.51.6-1.61.6-1.5-1.6-1.6-1.51.4-1.41.2-1.0
Bone: cortical porosity0.10.10.2-0.30.3-0.30.4-0.3-0.30.3-0.4-0.3-0.3-0.30.40.4-0.4-0.30.3-0.30.40.30.30.3-0.2-0.1-0.30.3
Bone: cortical porosity0.00.00.10.1-0.20.1-0.10.10.1-0.10.00.10.10.1-0.00.0-0.00.1-0.10.10.0-0.1-0.1-0.10.1-0.30.1-0.0
Bone: cortical thickness0.50.91.01.0-1.01.0-1.01.01.0-1.01.01.01.01.0-1.0-1.01.01.0-1.01.0-1.0-1.0-0.9-0.90.9-0.80.7-0.6
Bone: cortical thickness1.21.52.01.0-1.21.2-1.41.31.3-1.21.41.31.31.3-1.4-1.21.21.3-1.31.3-1.2-1.4-1.2-1.31.3-1.10.3-0.1
Bone: cortical tissue density0.10.10.3-0.20.4-0.40.4-0.4-0.40.4-0.5-0.4-0.4-0.40.50.3-0.3-0.40.3-0.40.30.40.50.3-0.40.5-0.10.1
Condit. Reinf. active minus inactive responses0.50.61.00.9-1.00.8-0.80.80.8-0.80.70.80.80.8-0.7-0.80.80.7-0.90.7-0.9-0.7-0.5-0.80.5-0.40.5-0.4
Condit. Reinf. active-inactive response ratio0.40.40.80.8-0.90.7-0.70.70.7-0.70.50.70.60.7-0.5-0.70.70.6-0.70.6-0.7-0.6-0.3-0.70.5-0.50.3-0.1
Condit. Reinf. active responses0.20.30.60.8-0.80.6-0.50.60.6-0.60.50.60.60.6-0.5-0.70.70.5-0.60.5-0.7-0.5-0.3-0.60.3-0.30.4-0.4
Condit. Reinf. inactive responses0.10.10.2-0.20.3-0.30.5-0.3-0.30.3-0.3-0.3-0.3-0.30.30.3-0.3-0.30.4-0.30.30.40.30.4-0.50.2-0.20.1
Incentive salience index mean0.30.40.90.9-1.00.7-0.60.70.7-0.70.60.70.70.7-0.5-0.80.80.6-0.70.6-0.8-0.6-0.4-0.60.3-0.50.4-0.3
Condit. Reinf. lever presses0.10.10.40.6-0.60.4-0.20.40.3-0.30.10.30.30.3-0.1-0.40.40.2-0.30.2-0.4-0.2-0.1-0.2-0.1-0.30.2-0.0
Condit. Reinf. active minus inactive responses0.00.10.10.2-0.20.2-0.30.20.2-0.20.30.20.20.2-0.3-0.20.20.2-0.30.2-0.2-0.2-0.2-0.30.3-0.10.3-0.3
Condit. Reinf. active-inactive response ratio0.20.30.60.3-0.30.5-0.60.50.5-0.50.60.50.50.5-0.6-0.40.40.5-0.50.5-0.4-0.6-0.6-0.70.8-0.50.3-0.2
Condit. Reinf. active responses0.10.10.3-0.20.3-0.30.3-0.3-0.30.3-0.3-0.3-0.3-0.30.30.3-0.3-0.30.2-0.30.30.30.40.2-0.30.50.0-0.1
Condit. Reinf. inactive responses0.50.71.5-0.70.8-0.90.9-0.9-0.90.9-0.9-0.9-0.9-0.90.90.8-0.8-0.90.8-0.90.80.91.00.9-1.01.2-0.30.1
Condit. Reinf. lever presses0.10.10.30.5-0.50.4-0.30.40.4-0.40.40.40.40.4-0.4-0.30.30.4-0.40.4-0.3-0.3-0.3-0.40.2-0.20.3-0.2
Condit. Reinf. lever reinforcers received0.10.10.4-0.30.3-0.40.4-0.4-0.40.4-0.3-0.4-0.4-0.40.30.4-0.4-0.40.3-0.40.40.40.40.3-0.40.6-0.1-0.0
Conditioned reinforcement - actives0.62.34.32.0-2.11.8-1.51.71.7-1.71.41.71.71.7-1.4-1.31.31.6-1.41.6-1.3-1.4-1.4-1.41.2-1.70.30.2
Conditioned reinforcement - inactives0.41.02.91.7-1.51.2-0.81.21.2-1.10.81.11.11.1-0.8-0.90.91.0-0.81.0-0.9-0.8-0.8-0.80.3-1.00.7-0.3
Conditioned locomotion1.72.53.51.4-1.41.6-1.71.61.6-1.61.71.61.61.6-1.7-1.61.61.7-1.61.6-1.6-1.7-1.7-1.71.9-1.40.10.1
Patch foraging indifference point 0 sec0.20.71.50.5-0.50.7-0.90.70.7-0.70.80.70.70.7-0.8-0.60.60.8-0.80.8-0.7-0.9-0.9-0.91.1-0.51.2-1.2
Patch foraging indifference point AUC2.14.96.52.5-2.52.3-2.22.32.3-2.32.32.32.32.3-2.3-2.52.52.2-2.42.2-2.5-2.1-2.2-2.11.8-2.40.6-0.2
Delay disc. indifference point, 0s delay0.80.91.7-0.50.5-0.91.1-0.9-0.90.9-1.2-0.9-0.9-0.91.21.0-1.0-1.01.0-1.01.01.11.21.2-1.30.7-0.30.3
Delay disc. indifference point, 16s delay0.70.91.5-0.60.5-0.91.1-0.9-0.90.9-1.1-0.9-0.9-0.91.11.0-1.0-1.01.2-1.01.01.11.21.0-1.20.5-0.70.8
Delay disc. indifference point, 2s delay2.83.14.7-1.31.2-1.62.0-1.7-1.71.7-1.9-1.7-1.7-1.71.91.8-1.8-1.82.0-1.81.71.92.11.8-2.21.5-1.71.8
Delay disc. indifference point, 24s delay0.00.00.2-0.1-0.00.1-0.20.10.1-0.10.20.10.10.1-0.20.0-0.00.1-0.10.1-0.0-0.20.0-0.00.2-0.50.2-0.1
Delay disc. indifference point, 4s delay0.10.10.80.5-0.40.10.00.10.1-0.10.10.10.10.1-0.0-0.10.10.00.10.0-0.20.00.10.0-0.10.30.9-0.8
Delay disc. indifference point, 8s delay0.91.51.8-1.21.2-1.31.3-1.3-1.31.3-1.3-1.3-1.3-1.31.31.2-1.2-1.41.3-1.31.11.41.41.3-1.31.1-0.40.3
Indifference point function ln k0.72.03.6-1.91.9-1.61.2-1.6-1.51.5-1.4-1.5-1.5-1.51.31.7-1.7-1.41.4-1.41.81.11.21.2-0.61.7-0.2-0.2
Indifference point function log k0.72.03.6-1.91.9-1.61.2-1.6-1.51.5-1.4-1.5-1.5-1.51.31.7-1.7-1.41.4-1.41.81.11.21.2-0.61.7-0.2-0.2
Patch foraging total patch changes 0 sec0.30.92.00.5-0.60.9-1.10.80.9-0.91.00.90.90.9-1.0-0.80.81.0-0.91.0-0.8-1.1-1.1-1.11.4-0.61.3-1.3
Patch foraging total patch changes 12 sec1.62.23.31.7-1.81.6-1.51.61.6-1.61.51.61.61.6-1.5-1.61.61.5-1.61.5-1.7-1.4-1.4-1.31.1-1.40.6-0.3
Patch foraging total patch changes 18 sec1.22.94.01.6-1.71.7-1.81.71.7-1.71.81.71.71.7-1.8-2.02.01.7-1.91.7-2.0-1.8-1.8-1.61.9-1.80.9-0.7
Patch foraging total patch changes 24 sec0.20.81.41.2-1.10.9-0.80.90.9-0.90.70.90.90.9-0.7-1.11.10.8-1.00.8-1.1-0.8-0.7-0.60.6-1.1-0.40.6
Patch foraging total patch changes 6 sec2.13.53.91.9-1.81.9-2.01.91.9-1.92.01.91.91.9-2.0-1.91.91.9-1.91.9-1.9-1.9-2.0-1.91.9-1.81.5-1.3
Patch foraging time to switch 0 sec1.14.15.1-1.91.7-2.12.2-2.1-2.12.1-2.3-2.1-2.1-2.12.32.1-2.1-2.22.1-2.12.02.22.22.1-2.22.2-0.80.5
Patch foraging water rate 0 sec1.35.16.22.1-2.02.3-2.52.32.3-2.32.52.32.32.3-2.5-2.32.32.4-2.32.4-2.2-2.4-2.4-2.42.4-2.11.2-0.9
Patch foraging water rate 12 sec0.00.10.30.3-0.30.4-0.50.40.4-0.40.40.40.40.4-0.4-0.30.30.4-0.50.4-0.2-0.5-0.4-0.40.4-0.60.00.0
Patch foraging water rate 18 sec0.00.10.20.3-0.20.4-0.40.30.4-0.30.30.30.30.3-0.3-0.00.00.4-0.10.40.0-0.4-0.3-0.30.3-0.10.1-0.0
Patch foraging water rate 24 sec0.30.50.90.3-0.40.6-0.90.60.6-0.60.90.70.70.6-0.9-0.80.80.7-0.90.7-0.6-0.9-0.8-0.81.0-0.60.0-0.0
Patch foraging water rate 6 sec0.50.81.21.1-0.91.0-0.91.01.0-1.00.90.90.90.9-0.9-0.80.80.9-0.90.9-0.8-0.9-0.8-0.90.8-1.0-0.10.3
Seeking ratio, delayed vs. immediate footshock1.72.43.5-1.71.7-1.61.5-1.6-1.61.6-1.5-1.6-1.6-1.61.61.3-1.3-1.61.5-1.61.41.51.51.5-1.31.6-1.91.6
Distance traveled before self-admin0.00.00.10.0-0.20.2-0.20.20.2-0.20.20.20.20.2-0.3-0.00.00.20.10.20.0-0.2-0.2-0.30.4-0.10.3-0.2
Distance traveled after self-admin0.20.30.6-0.80.6-0.60.5-0.6-0.60.6-0.5-0.6-0.5-0.60.50.7-0.7-0.50.7-0.50.80.50.50.5-0.40.7-0.60.5
Extensor digitorum longus weight2.08.09.73.0-2.92.9-2.82.92.9-2.92.72.92.82.9-2.7-2.82.82.8-2.72.8-2.9-2.8-2.7-2.62.7-2.53.1-2.8
Bone: elastic displacement0.60.81.2-1.00.9-1.00.8-1.0-1.01.0-1.1-0.9-1.0-1.01.10.8-0.8-0.90.8-0.90.70.81.00.9-0.60.8-0.40.1
Bone: elastic work0.10.10.80.3-0.50.3-0.30.30.3-0.30.20.30.30.3-0.2-0.30.30.2-0.40.2-0.3-0.3-0.1-0.20.20.10.8-0.9
Bone: endosteal estimation0.00.00.20.0-0.2-0.10.2-0.1-0.10.1-0.2-0.1-0.1-0.10.20.2-0.2-0.20.2-0.20.20.30.20.3-0.5-0.1-0.10.3
Bone: endosteal perimeter0.00.00.30.4-0.30.20.00.10.1-0.1-0.00.10.10.10.00.0-0.00.0-0.00.10.10.0-0.10.0-0.2-0.20.6-0.4
Epididymis fat weight0.10.51.1-0.50.4-0.70.8-0.7-0.70.7-0.9-0.7-0.7-0.70.90.8-0.8-0.80.6-0.70.60.80.80.8-1.00.8-0.70.5
Delta time in closed arm before/after self-admin0.30.30.8-0.80.8-0.60.4-0.6-0.60.6-0.4-0.5-0.5-0.60.40.5-0.5-0.50.6-0.50.90.30.40.3-0.10.90.3-0.6
Delta time in open arm before/after self-admin0.10.11.10.5-0.40.20.20.10.1-0.1-0.10.10.10.10.1-0.20.2-0.0-0.1-0.0-0.50.20.10.2-0.6-0.2-0.71.0
Diff in mean of infusions in LGA sessions1.01.83.6-1.71.6-1.51.2-1.4-1.41.4-1.2-1.4-1.4-1.41.21.0-1.0-1.31.1-1.31.01.31.21.3-1.01.2-1.91.7
Delay discount exponential model param0.81.01.70.7-0.71.0-1.11.01.0-1.01.11.01.01.0-1.1-1.11.11.1-1.21.1-1.0-1.1-1.3-1.11.2-0.90.6-0.6
Extinction: sum of active levers before priming0.00.10.6-0.20.1-0.20.0-0.2-0.20.2-0.1-0.2-0.2-0.20.1-0.10.1-0.2-0.1-0.2-0.00.20.10.2-0.20.20.6-0.8
Active lever presses in extinction session 60.20.20.50.5-0.70.4-0.40.40.4-0.40.30.40.40.4-0.3-0.30.30.4-0.50.4-0.4-0.3-0.4-0.20.3-0.50.7-0.6
Bone: final force0.40.71.21.0-1.10.9-0.80.90.9-0.90.80.90.90.9-0.8-0.90.90.8-0.90.8-0.9-0.8-0.8-0.70.6-1.00.7-0.5
Bone: final moment0.71.11.71.2-1.31.1-1.01.11.1-1.11.01.11.11.1-1.0-1.11.11.0-1.01.0-1.0-1.0-0.9-0.90.7-1.21.0-0.8
Food consumed during 24 hour testing period3.57.09.9-2.72.7-2.72.8-2.7-2.72.7-2.8-2.7-2.7-2.72.82.6-2.6-2.72.6-2.72.72.72.72.7-2.73.1-1.61.1
Glucose0.30.51.0-0.90.8-0.80.6-0.7-0.70.7-0.6-0.7-0.7-0.70.60.7-0.7-0.70.6-0.60.70.60.60.5-0.40.8-1.00.8
Heart weight1.82.93.81.5-1.51.7-1.91.71.7-1.71.91.71.71.7-2.0-1.61.61.8-1.71.8-1.6-1.9-1.9-1.81.9-1.11.3-1.2
Delay discount hyperbolic model param0.70.91.50.6-0.60.9-1.10.90.9-0.91.01.01.01.0-1.0-1.01.01.0-1.21.0-0.9-1.1-1.2-1.01.2-0.80.5-0.5
Intermittent access intake day 1-15 change0.00.20.60.5-0.60.5-0.40.50.4-0.50.40.40.40.5-0.4-0.30.30.4-0.40.4-0.3-0.3-0.3-0.30.3-0.80.1-0.1
Intermittent access intake escalation0.10.30.80.7-0.80.6-0.50.60.6-0.60.50.60.60.6-0.5-0.40.40.5-0.50.5-0.4-0.4-0.4-0.40.3-0.90.1-0.0
Intermittent access intake escalation 20.00.00.2-0.20.0-0.1-0.1-0.1-0.10.00.1-0.0-0.0-0.0-0.10.0-0.0-0.0-0.1-0.00.0-0.0-0.0-0.00.3-0.30.3-0.4
Intermitt. access day 1 inactive lever presses0.00.33.40.6-0.40.3-0.00.30.3-0.30.10.20.20.2-0.1-0.40.40.2-0.20.2-0.3-0.0-0.0-0.0-0.2-0.51.8-1.6
Intermitt. access day 15 inactive lever presses0.00.10.70.6-0.10.20.20.20.2-0.2-0.10.20.10.10.1-0.30.30.1-0.20.1-0.50.0-0.0-0.1-0.2-0.9-0.20.3
Intermitt. access escalation Index0.10.30.8-0.80.9-0.60.5-0.6-0.60.6-0.5-0.6-0.6-0.60.50.4-0.4-0.60.5-0.60.40.50.50.5-0.40.50.1-0.3
Intermittent access day 1 total infusions0.92.74.92.2-2.11.9-1.61.81.8-1.81.61.81.81.8-1.6-1.71.71.7-1.71.7-1.5-1.6-1.5-1.61.1-1.60.00.4
Intermittent access day 15 total infusions0.51.32.11.5-1.41.2-1.11.31.2-1.21.11.21.21.2-1.1-1.31.31.1-1.21.2-1.2-1.0-1.0-1.00.7-1.3-0.30.6
Intermittent access terminal intake (last 3 days)0.91.52.01.4-1.41.3-1.31.31.3-1.31.31.31.31.3-1.3-1.41.41.2-1.31.3-1.3-1.2-1.1-1.21.0-1.20.1-0.0
Intermittent access total infusions2.52.93.91.9-1.81.8-1.81.81.8-1.81.81.81.81.8-1.8-2.02.01.8-1.81.8-1.8-1.7-1.7-1.71.4-1.60.4-0.2
Intermittent access day 1 locomotion0.20.41.21.1-0.80.8-0.60.80.8-0.70.60.70.70.7-0.6-0.80.80.7-0.60.7-0.7-0.6-0.6-0.60.2-0.5-0.10.3
Intermittent access day 15 total locomotion0.10.31.20.7-0.60.5-0.50.60.5-0.50.50.50.50.5-0.5-0.30.30.5-0.50.5-0.3-0.5-0.5-0.50.2-0.3-1.01.1
Intermittent access total locomotion1.51.82.71.6-1.31.5-1.41.51.5-1.41.41.51.51.4-1.4-1.41.41.4-1.41.4-1.3-1.4-1.4-1.41.1-1.20.10.2
Intermittent access standard deviation0.00.20.2-0.50.5-0.50.5-0.5-0.50.5-0.4-0.5-0.5-0.50.40.3-0.3-0.50.4-0.50.30.50.50.4-0.40.3-0.0-0.1
Left kidney weight3.125.029.85.3-5.55.2-5.25.25.2-5.25.25.25.25.2-5.2-5.25.25.1-5.15.1-5.2-4.9-4.9-4.94.4-4.04.3-3.7
Right kidney weight3.322.925.64.9-5.04.9-5.04.94.9-4.95.04.94.94.9-5.0-5.15.14.8-4.94.9-5.1-4.8-4.7-4.64.3-4.14.1-3.5
Cocaine induced anxiety0.00.10.3-0.00.1-0.20.4-0.3-0.30.3-0.5-0.3-0.3-0.30.50.2-0.2-0.40.4-0.40.10.40.40.4-0.50.0-0.40.6
Post-drug Anxiety0.00.00.2-0.10.2-0.10.1-0.1-0.10.1-0.1-0.1-0.1-0.10.10.1-0.1-0.10.0-0.10.10.10.10.10.00.0-0.40.5
Baseline Anxiety0.10.21.0-1.01.0-0.5-0.0-0.5-0.40.40.0-0.4-0.4-0.4-0.10.2-0.2-0.2-0.0-0.20.4-0.0-0.0-0.00.60.7-0.2-0.3
Tail length0.42.24.22.1-1.91.6-1.31.61.6-1.51.21.51.51.5-1.2-1.31.31.4-1.31.4-1.5-1.2-1.2-1.20.9-1.61.9-1.5
Length with tail0.42.03.51.9-1.81.5-1.31.51.5-1.51.21.51.51.5-1.2-1.41.41.3-1.31.3-1.5-1.2-1.2-1.10.9-1.31.7-1.3
Length without tail0.21.21.71.2-1.21.1-1.01.11.1-1.11.11.11.11.1-1.0-1.31.31.0-1.11.0-1.3-1.0-1.0-0.90.8-0.51.2-1.1
Times rat made contact with spout0.10.10.4-0.60.5-0.30.2-0.3-0.30.3-0.2-0.3-0.3-0.30.10.2-0.2-0.20.2-0.20.20.20.20.1-0.00.5-0.20.1
Lifetime Intake2.53.14.32.1-2.01.9-1.81.91.9-1.91.81.91.91.9-1.8-2.02.01.8-1.91.8-1.9-1.7-1.7-1.71.4-1.60.5-0.2
Liver weight, left2.23.85.02.1-2.22.1-2.12.12.1-2.12.02.12.12.1-2.0-1.91.92.0-2.02.0-1.9-2.0-2.0-1.91.9-1.71.3-0.9
Liver weight, right1.62.84.22.0-2.11.8-1.81.81.8-1.81.61.71.71.7-1.6-1.81.81.6-1.81.6-1.8-1.6-1.4-1.51.2-1.51.6-1.2
Locomotor activity2.03.14.01.6-1.71.8-1.91.81.8-1.82.01.81.81.8-2.0-1.61.61.8-1.91.8-1.6-1.9-1.9-1.91.9-1.21.6-1.4
Locomotor testing distance0.81.92.61.4-1.61.5-1.41.51.5-1.41.51.51.51.5-1.5-1.21.21.5-1.41.5-1.2-1.4-1.6-1.51.3-1.01.1-0.7
Locomotor testing rearing2.38.610.73.1-3.33.1-3.03.13.1-3.13.13.13.13.0-3.1-2.92.93.0-3.03.0-3.0-2.9-3.0-3.02.7-2.62.0-1.5
Locomotion in novel chamber0.40.51.4-1.21.2-0.80.5-0.8-0.80.7-0.4-0.7-0.7-0.70.40.7-0.7-0.60.6-0.60.90.50.50.5-0.20.9-0.60.2
Locomotion in novel chamber post-restriction0.51.52.6-1.31.2-1.31.3-1.3-1.21.3-1.4-1.3-1.2-1.31.41.3-1.3-1.21.3-1.21.31.21.11.1-1.21.6-0.50.3
Fecal boli incidents, locomotor time 10.10.21.30.4-0.30.4-0.30.30.3-0.30.30.30.30.3-0.3-0.20.20.3-0.20.3-0.2-0.2-0.3-0.30.20.51.1-1.1
Change in fecal boli incidents, locomotor task0.60.61.0-0.90.6-0.80.9-0.8-0.80.8-0.9-0.8-0.8-0.80.90.7-0.7-0.80.8-0.80.70.90.91.0-1.00.2-0.40.5
Time >=10cm from walls, locomotor time 10.00.10.5-0.30.1-0.10.0-0.1-0.10.1-0.1-0.1-0.0-0.10.10.0-0.0-0.10.1-0.10.10.10.10.1-0.10.70.6-0.7
Bouts of movement, locomotor time 12.12.83.9-2.01.7-1.81.6-1.8-1.81.8-1.7-1.8-1.7-1.81.71.6-1.6-1.71.6-1.71.51.61.71.7-1.61.6-1.31.1
Total resting periods, locomotor time 13.13.64.4-2.11.9-2.01.9-2.0-2.02.0-1.9-2.0-1.9-2.01.91.8-1.8-1.91.8-1.91.61.91.92.0-1.91.8-1.71.5
Rest time, locomotor task time 10.10.20.4-0.50.5-0.50.5-0.5-0.50.5-0.5-0.5-0.5-0.50.50.4-0.4-0.50.5-0.50.30.50.40.6-0.60.3-0.50.4
Distance moved, locomotor task time 10.20.71.20.9-0.90.8-0.80.80.8-0.80.80.80.80.8-0.8-0.80.80.8-0.80.8-0.8-0.8-0.7-0.80.8-0.61.1-1.1
Vertical activity count, locomotor time 10.00.00.30.3-0.50.2-0.10.20.2-0.20.10.20.20.2-0.1-0.10.10.1-0.10.1-0.1-0.0-0.00.0-0.10.00.5-0.4
Time >=10cm from walls, locomotor time 20.00.10.20.0-0.0-0.20.4-0.2-0.20.2-0.3-0.2-0.2-0.20.30.3-0.3-0.20.3-0.20.40.30.20.2-0.40.40.2-0.2
Bouts of movement, locomotor time 22.37.58.7-2.82.9-2.92.8-2.9-2.92.9-2.8-2.9-2.9-2.92.82.7-2.7-2.82.7-2.82.62.72.82.7-2.42.4-2.62.1
Total resting periods, locomotor time 21.76.88.5-2.82.9-2.82.7-2.8-2.82.8-2.6-2.8-2.8-2.72.62.5-2.5-2.72.6-2.72.42.62.72.5-2.22.4-2.51.9
Rest time, locomotor task time 20.10.10.7-0.60.8-0.50.3-0.5-0.40.5-0.3-0.4-0.4-0.40.30.1-0.1-0.30.2-0.30.00.20.20.2-0.10.5-0.1-0.1
Distance moved, locomotor task time 20.81.12.31.2-1.31.1-1.01.11.1-1.11.01.11.11.1-1.1-0.90.91.0-1.01.0-0.9-1.0-0.9-1.00.9-1.50.6-0.3
Vertical activity count, locomotor time 20.00.00.20.3-0.50.10.10.10.1-0.1-0.10.00.00.00.10.2-0.2-0.10.1-0.10.20.20.20.3-0.5-0.30.2-0.0
Light reinforcement 10.00.10.20.3-0.40.4-0.30.30.4-0.30.30.30.30.3-0.3-0.20.20.3-0.30.3-0.3-0.3-0.4-0.30.30.1-0.10.2
Light reinforcement 20.10.30.90.9-1.00.7-0.20.60.6-0.60.30.50.50.5-0.3-0.50.50.4-0.30.4-0.6-0.2-0.4-0.2-0.2-0.50.4-0.1
Bone: marrow area0.00.00.10.1-0.20.00.1-0.0-0.00.0-0.2-0.0-0.0-0.00.20.1-0.1-0.10.1-0.10.10.20.10.2-0.4-0.1-0.10.2
Bone: maximum diameter2.24.35.02.2-2.22.2-2.22.22.1-2.22.12.12.12.2-2.1-2.12.12.1-2.22.1-2.1-2.1-2.1-2.01.9-2.01.7-1.4
Bone: maximum force0.20.40.70.8-0.90.7-0.50.70.6-0.60.60.60.60.6-0.5-0.60.60.6-0.60.6-0.6-0.5-0.5-0.40.2-0.70.8-0.6
Bone: maximum moment0.30.61.11.0-1.00.8-0.60.80.8-0.80.70.80.80.8-0.6-0.70.70.7-0.70.7-0.7-0.6-0.6-0.50.3-0.81.0-0.9
Mean time between licks in bursts0.00.10.3-0.00.1-0.20.3-0.2-0.20.2-0.3-0.2-0.2-0.20.30.1-0.1-0.20.1-0.20.10.30.30.3-0.40.10.4-0.5
Mean num. licks in bursts1.84.96.1-2.52.2-2.32.2-2.3-2.32.3-2.2-2.3-2.2-2.32.22.2-2.2-2.22.2-2.22.22.22.22.2-2.12.1-2.32.0
Cd content in liver0.20.20.5-0.70.7-0.50.3-0.5-0.50.4-0.3-0.4-0.4-0.40.30.2-0.2-0.40.3-0.40.20.30.30.3-0.10.5-0.60.5
Co content in liver1.21.42.0-1.21.4-1.21.3-1.2-1.21.2-1.2-1.2-1.2-1.21.31.0-1.0-1.21.0-1.21.01.21.21.2-1.21.3-0.60.3
Cu content in liver0.40.51.10.8-0.70.7-0.70.70.7-0.70.70.70.70.7-0.7-0.80.80.7-0.80.7-0.8-0.7-0.7-0.60.7-1.00.00.2
Fe content in liver4.55.67.32.1-2.02.3-2.62.32.4-2.42.62.42.42.4-2.6-2.52.52.5-2.52.5-2.5-2.6-2.5-2.62.7-2.01.5-1.3
K content in liver0.30.30.60.6-0.80.6-0.50.60.6-0.60.50.60.60.5-0.5-0.40.40.5-0.40.5-0.4-0.5-0.5-0.40.3-0.40.6-0.5
Mg content in liver0.70.71.30.9-1.10.9-0.90.90.9-0.90.90.90.90.9-0.9-0.80.80.9-0.80.9-0.8-0.8-0.8-0.80.6-0.60.9-0.7
Mn content in liver1.11.21.81.2-1.31.2-1.11.11.1-1.11.11.11.11.1-1.1-1.11.11.1-1.11.1-1.1-1.0-1.0-1.00.8-1.01.1-0.9
Na content in liver0.10.20.7-0.10.00.3-0.50.30.3-0.30.50.40.40.3-0.5-0.20.20.5-0.30.4-0.2-0.6-0.6-0.40.8-0.20.1-0.2
Rb content in liver0.10.10.20.1-0.30.2-0.30.20.2-0.20.30.20.20.2-0.3-0.10.10.2-0.20.2-0.1-0.3-0.3-0.20.30.10.4-0.4
Se content in liver4.14.95.92.4-2.42.4-2.32.32.3-2.32.22.32.32.3-2.2-2.22.22.3-2.32.3-2.2-2.2-2.2-2.22.1-2.41.2-0.8
Sr content in liver0.10.00.10.3-0.20.2-0.20.20.2-0.20.20.20.20.2-0.2-0.20.20.2-0.20.2-0.2-0.2-0.2-0.20.2-0.40.2-0.1
Zn content in liver1.01.12.21.3-1.31.2-1.01.11.1-1.10.91.11.11.1-0.9-1.01.01.1-1.01.0-1.0-1.0-1.0-0.90.9-1.50.9-0.7
Bone: minimum diameter0.20.40.80.9-0.70.7-0.60.70.7-0.70.50.60.60.7-0.5-0.50.50.6-0.50.6-0.5-0.6-0.6-0.50.4-0.70.8-0.7
Time in familiar zone, hab. session 10.10.20.60.3-0.30.3-0.40.30.3-0.30.40.30.40.3-0.4-0.20.20.4-0.30.4-0.2-0.4-0.5-0.40.5-0.20.8-0.8
Time in novel zone, hab. session 10.70.71.50.9-0.80.9-0.90.90.9-0.90.80.90.90.9-0.8-1.01.00.8-0.90.8-1.0-0.8-0.7-0.80.8-1.2-0.20.4
Total zone transitions, hab. session 10.10.10.20.1-0.30.3-0.40.30.3-0.30.40.30.30.3-0.4-0.20.20.3-0.30.4-0.2-0.4-0.4-0.40.5-0.1-0.10.2
Total locomotion distance, hab. session 10.40.60.7-0.70.6-0.70.8-0.7-0.70.7-0.8-0.7-0.7-0.70.80.8-0.8-0.70.7-0.70.80.70.80.7-0.70.6-0.70.7
Locomotion velocity, hab. session 11.21.71.9-1.31.1-1.31.4-1.3-1.31.3-1.4-1.3-1.3-1.31.41.4-1.4-1.31.3-1.31.41.31.41.3-1.31.3-0.90.8
Time in familiar zone, hab. session 20.30.40.50.6-0.70.6-0.70.60.6-0.60.60.60.60.6-0.6-0.70.70.6-0.60.6-0.7-0.7-0.6-0.70.7-0.70.4-0.2
Time in novel zone, hab. session 20.20.20.4-0.60.6-0.40.3-0.4-0.40.4-0.3-0.4-0.4-0.40.30.5-0.5-0.30.4-0.30.50.30.30.3-0.10.4-0.60.5
Total zone transitions, hab. session 20.40.60.90.6-0.70.8-0.90.80.8-0.80.90.80.80.8-0.9-0.70.70.8-0.80.8-0.7-0.9-0.9-0.81.0-0.60.4-0.2
Total locomotion distance, hab. session 20.50.60.8-0.90.8-0.80.8-0.8-0.80.8-0.8-0.8-0.8-0.80.80.9-0.9-0.80.8-0.80.90.70.80.7-0.70.8-0.70.7
Locomotion velocity, hab. session 20.30.40.6-0.70.5-0.60.7-0.6-0.60.6-0.7-0.6-0.6-0.60.70.8-0.8-0.60.7-0.70.80.60.70.6-0.60.7-0.50.5
Novel to familiar place preference ratio0.30.40.80.8-0.70.7-0.50.70.7-0.70.60.60.60.7-0.6-0.50.50.6-0.40.6-0.5-0.5-0.6-0.50.4-0.9-0.00.2
Novelty place preference0.20.30.60.7-0.60.6-0.40.60.6-0.60.60.60.60.6-0.6-0.40.40.6-0.30.6-0.4-0.5-0.6-0.50.4-0.8-0.10.3
Time in novel zone, NPP test0.30.40.90.8-0.60.7-0.50.70.7-0.70.70.70.70.7-0.7-0.50.50.7-0.50.7-0.5-0.6-0.7-0.60.6-0.9-0.20.4
Total zone transitions, NPP test0.10.10.20.3-0.40.3-0.40.30.3-0.30.40.30.30.3-0.4-0.20.20.3-0.40.4-0.2-0.4-0.4-0.30.4-0.20.2-0.1
Total locomotion distance, NPP test0.00.10.20.1-0.20.2-0.30.20.2-0.20.30.20.20.2-0.3-0.10.10.3-0.30.3-0.1-0.3-0.4-0.30.4-0.2-0.10.2
Locomotion velocity, NPP test0.00.00.10.1-0.20.2-0.20.20.2-0.20.30.20.20.2-0.3-0.10.10.2-0.20.2-0.0-0.2-0.3-0.20.3-0.10.00.0
Intraocular pressure0.10.21.5-0.30.4-0.30.0-0.2-0.30.2-0.1-0.2-0.2-0.20.10.1-0.1-0.1-0.0-0.10.20.00.1-0.10.31.10.8-1.2
Delta distance traveled before/after self-admin1.41.63.1-0.90.9-1.11.4-1.1-1.11.2-1.4-1.2-1.2-1.21.41.3-1.3-1.31.2-1.31.21.41.31.4-1.71.0-1.21.3
Delta ambulatory time before/after self-admin0.20.40.8-0.30.4-0.50.7-0.5-0.50.6-0.7-0.6-0.6-0.60.70.8-0.8-0.60.6-0.60.70.70.60.7-0.90.4-0.90.9
Parametrial fat weight0.10.20.30.2-0.40.4-0.50.40.4-0.40.50.40.40.4-0.5-0.50.50.4-0.50.4-0.4-0.4-0.3-0.30.2-0.1-0.40.5
Pavlov. Cond. lever latency0.50.70.9-0.70.9-0.80.9-0.8-0.80.8-0.8-0.8-0.8-0.80.80.8-0.8-0.80.9-0.80.90.90.70.9-0.90.90.1-0.3
Pavlov. Cond. magazine entry latency0.10.20.40.5-0.60.4-0.40.40.4-0.40.30.40.40.4-0.3-0.40.40.3-0.40.4-0.4-0.4-0.2-0.40.3-0.4-0.30.6
Pavlov. Cond. change in total contacts0.60.60.9-0.70.6-0.80.8-0.8-0.80.8-0.8-0.8-0.8-0.80.80.7-0.7-0.80.8-0.80.70.80.90.7-0.80.8-1.00.9
Pavlov. Cond. index score0.30.40.50.6-0.70.6-0.70.60.6-0.60.60.60.60.6-0.6-0.60.60.6-0.60.6-0.6-0.7-0.5-0.70.6-0.6-0.20.4
Pavlov. Cond. latency score0.10.10.40.3-0.40.3-0.40.30.3-0.30.30.30.30.3-0.2-0.30.30.3-0.40.3-0.4-0.4-0.2-0.40.3-0.3-0.50.7
Pavlov. Cond. lever contacts0.40.40.60.5-0.70.7-0.80.70.7-0.70.60.70.70.7-0.6-0.70.70.6-0.70.7-0.7-0.7-0.5-0.70.7-0.7-0.20.3
Pavlov. Cond. magazine entry number0.10.10.7-0.30.4-0.20.3-0.2-0.20.2-0.1-0.2-0.2-0.20.10.2-0.2-0.20.3-0.20.20.30.00.3-0.20.20.6-0.8
Pavlov. Cond. intertrial magazine entries0.10.10.50.10.00.1-0.20.20.1-0.20.30.20.20.2-0.3-0.40.40.2-0.30.2-0.4-0.2-0.3-0.20.20.00.6-0.7
Pavlov. Cond. lever-magazine prob. diff.0.30.40.60.6-0.70.6-0.70.60.6-0.60.60.60.60.6-0.6-0.60.60.6-0.70.6-0.7-0.7-0.5-0.80.7-0.6-0.10.3
Pavlov. Cond. response bias0.91.11.61.2-1.31.1-1.21.11.1-1.11.01.11.11.1-1.0-1.11.11.1-1.11.1-1.1-1.1-0.9-1.21.0-1.00.10.2
Pavlov. Cond. lever latency0.00.10.4-0.40.2-0.20.1-0.2-0.20.2-0.1-0.2-0.2-0.20.10.1-0.1-0.10.2-0.10.10.10.10.10.0-0.1-0.60.6
Pavlov. Cond. magazine entry latency0.00.00.40.0-0.10.0-0.00.00.0-0.00.10.00.00.0-0.1-0.10.10.0-0.10.0-0.20.00.0-0.0-0.10.30.5-0.6
Pavlov. Cond. change in total contacts0.20.41.0-0.60.7-0.60.6-0.6-0.60.6-0.5-0.6-0.6-0.60.50.7-0.7-0.60.6-0.60.70.60.60.6-0.51.0-0.1-0.0
Pavlov. Cond. index score0.00.10.4-0.10.1-0.20.3-0.2-0.20.2-0.2-0.2-0.2-0.20.20.2-0.2-0.20.1-0.20.20.30.20.2-0.40.60.5-0.6
Pavlov. Cond. latency score0.10.10.4-0.20.2-0.30.4-0.3-0.30.3-0.3-0.3-0.3-0.30.30.3-0.3-0.30.2-0.30.30.40.30.3-0.50.60.4-0.5
Pavlov. Cond. lever contacts0.10.20.70.6-0.50.4-0.30.40.4-0.40.30.30.30.4-0.3-0.30.30.3-0.40.3-0.3-0.2-0.2-0.30.10.00.9-0.8
Pavlov. Cond. magazine entry number0.30.41.10.6-0.50.6-0.70.60.6-0.60.60.70.60.7-0.6-0.60.60.7-0.60.7-0.6-0.8-0.7-0.70.8-1.1-0.00.2
Pavlov. Cond. intertrial magazine entries0.00.00.20.10.10.0-0.10.00.0-0.00.10.00.00.0-0.10.0-0.00.1-0.00.10.0-0.1-0.1-0.10.3-0.3-0.40.5
Pavlov. Cond. lever-magazine prob. diff.0.00.00.40.1-0.10.00.1-0.0-0.00.00.0-0.0-0.0-0.0-0.00.0-0.0-0.0-0.0-0.00.00.10.10.0-0.20.40.6-0.6
Pavlov. Cond. response bias0.00.10.70.2-0.1-0.00.1-0.0-0.00.0-0.0-0.0-0.0-0.00.00.0-0.0-0.1-0.0-0.10.10.10.10.1-0.20.50.8-0.8
Time in closed arm before self-admin0.50.81.40.9-0.91.0-0.91.01.0-1.01.00.90.91.0-1.0-1.01.00.9-1.00.9-1.2-0.9-0.9-0.90.9-1.00.10.2
Time in closed arm after self-admin1.01.22.1-1.41.4-1.21.0-1.2-1.11.1-1.0-1.1-1.1-1.11.01.1-1.1-1.01.1-1.11.21.01.00.9-0.61.2-1.00.7
Time in open arm before self-admin0.60.81.4-0.80.7-0.90.7-0.9-0.90.9-0.9-0.9-0.9-0.90.91.1-1.1-0.91.0-0.91.20.80.80.8-0.71.10.3-0.5
Time in open arm after self-admin0.10.10.40.3-0.3-0.10.2-0.1-0.10.1-0.2-0.1-0.1-0.10.30.1-0.1-0.20.1-0.2-0.20.30.20.3-0.60.10.5-0.4
Bone: periosteal estimation0.30.61.11.0-1.00.9-0.80.90.8-0.80.70.80.80.8-0.7-0.70.70.8-0.80.8-0.6-0.7-0.8-0.60.5-0.80.6-0.4
Bone: periosteal perimeter0.30.61.31.2-1.10.9-0.70.90.8-0.90.70.80.80.8-0.6-0.70.70.8-0.70.8-0.6-0.7-0.7-0.70.4-0.90.9-0.7
Bone: post-yield work0.61.02.2-0.40.6-0.81.3-0.9-0.90.9-1.2-0.9-0.9-0.91.21.0-1.0-1.01.1-1.01.01.21.11.1-1.50.8-0.20.2
Progressive ratio test 1 active lever presses2.03.55.82.4-2.32.1-1.92.12.1-2.01.82.02.02.0-1.8-1.81.81.9-1.91.9-1.8-1.8-1.8-1.81.4-1.90.8-0.3
Progressive ratio test 1 breakpoint1.93.25.32.3-2.32.0-1.82.02.0-1.91.81.91.91.9-1.8-1.71.71.8-1.81.8-1.7-1.7-1.6-1.71.2-1.61.0-0.5
Progressive ratio test 1 inactive lever presses0.82.13.92.0-1.91.7-1.31.61.6-1.61.41.61.61.6-1.3-1.21.21.5-1.51.5-1.3-1.3-1.3-1.31.0-1.61.3-0.8
Progressive ratio test 2 active lever presses2.23.15.22.3-2.12.0-1.81.91.9-1.91.71.91.91.9-1.7-1.81.81.8-1.91.8-1.8-1.7-1.7-1.71.4-1.90.40.1
Progressive ratio test 2 breakpoint2.73.55.52.3-2.22.1-1.92.02.0-2.01.82.02.02.0-1.8-1.91.91.9-1.91.9-1.9-1.8-1.8-1.81.5-2.10.50.0
Progressive ratio test 2 inactive lever presses0.20.62.41.5-1.41.0-0.51.00.9-0.90.50.90.90.9-0.4-0.60.60.7-0.70.7-0.6-0.5-0.5-0.5-0.0-1.10.10.4
Incentive Sensitization - Responses0.71.92.81.7-1.61.5-1.41.51.5-1.51.31.51.41.5-1.3-1.41.41.4-1.41.4-1.4-1.3-1.3-1.31.2-1.50.00.4
Incentive Sensitization - Breakpoint0.81.72.61.6-1.51.4-1.31.41.4-1.41.31.41.41.4-1.2-1.41.41.3-1.41.3-1.4-1.3-1.2-1.31.2-1.6-0.20.5
Sum of active levers in priming session hrs 5-60.30.30.9-0.90.9-0.70.3-0.6-0.60.6-0.3-0.6-0.6-0.60.30.2-0.2-0.50.2-0.50.30.40.40.5-0.10.8-0.1-0.1
Progressive ratio0.61.62.1-1.51.4-1.31.2-1.3-1.31.3-1.3-1.3-1.3-1.31.31.2-1.2-1.31.1-1.21.21.21.21.1-1.11.4-1.51.2
Food seeking constrained by brief footshock4.96.17.9-2.12.5-2.52.8-2.5-2.52.5-2.7-2.5-2.5-2.52.72.6-2.6-2.62.7-2.62.72.72.52.6-2.51.9-1.91.6
Seeking ratio, punishment vs. effort0.30.71.3-0.30.5-0.71.1-0.8-0.80.7-1.0-0.8-0.8-0.81.00.9-0.9-0.91.1-0.91.01.10.91.1-1.00.30.00.0
Retroperitoneal fat weight0.00.20.40.3-0.50.3-0.50.40.4-0.40.50.40.40.4-0.5-0.50.50.4-0.50.4-0.5-0.4-0.4-0.40.30.30.5-0.7
Reaction time number correct1.96.69.32.1-2.12.5-2.92.52.5-2.52.82.52.52.5-2.9-2.52.52.6-2.72.6-2.4-2.8-2.7-2.73.0-1.52.6-2.6
Reaction time mean minus median0.10.51.6-1.21.3-0.90.5-0.8-0.80.8-0.4-0.8-0.8-0.70.30.6-0.6-0.60.4-0.60.60.50.40.50.00.9-0.4-0.0
Reaction time mean minus median AUC0.00.10.5-0.40.5-0.1-0.3-0.1-0.10.00.4-0.0-0.00.0-0.4-0.10.10.1-0.40.1-0.2-0.3-0.3-0.20.70.30.3-0.7
Reaction time num false alarms3.96.68.32.7-2.92.7-2.72.72.7-2.72.62.72.72.6-2.6-2.72.72.6-2.62.6-2.6-2.6-2.4-2.42.2-2.02.5-2.1
Reaction time num false alarms AUC2.65.97.52.6-2.72.6-2.52.52.5-2.52.42.52.52.5-2.4-2.52.52.4-2.52.4-2.4-2.4-2.3-2.32.1-1.92.4-2.1
Reaction time trials correct on left1.96.69.32.1-2.12.5-2.92.52.5-2.52.82.52.52.5-2.9-2.52.52.6-2.72.6-2.4-2.8-2.7-2.73.0-1.52.6-2.6
Reaction time trials on left1.96.69.12.1-2.12.5-2.92.52.5-2.52.82.52.52.5-2.9-2.52.52.6-2.72.6-2.5-2.8-2.7-2.73.0-1.52.7-2.6
Reaction time mean0.92.12.8-1.71.7-1.61.5-1.6-1.61.6-1.4-1.6-1.6-1.61.41.3-1.3-1.51.3-1.51.31.51.41.5-1.31.3-0.90.6
Reaction time mean AUC0.71.62.3-1.51.5-1.41.3-1.4-1.41.4-1.2-1.4-1.4-1.41.21.2-1.2-1.31.1-1.31.21.31.21.3-1.11.0-0.70.4
Median of all reaction times1.42.12.6-1.51.5-1.61.6-1.6-1.61.6-1.5-1.6-1.6-1.61.51.3-1.3-1.61.4-1.61.41.61.51.6-1.61.2-0.80.6
Reaction time omissions0.10.11.00.4-0.40.10.00.10.1-0.10.00.10.10.1-0.0-0.20.20.0-0.20.0-0.30.10.10.1-0.2-0.21.0-1.0
Reaction time false alarm rate0.30.41.11.0-1.10.7-0.50.70.7-0.70.40.70.70.6-0.4-0.70.70.5-0.60.6-0.6-0.4-0.4-0.50.1-0.60.6-0.3
Reaction time premature initiation rate0.50.83.0-0.70.4-0.70.8-0.7-0.70.7-0.9-0.7-0.7-0.70.91.1-1.1-0.80.9-0.81.10.80.80.8-0.90.3-1.51.7
Reaction time premature initiations0.10.20.60.2-0.50.5-0.70.50.5-0.50.60.50.50.5-0.6-0.10.10.6-0.40.6-0.1-0.7-0.6-0.60.8-0.3-0.00.1
Std. dev. reaction times0.20.61.4-1.21.2-1.00.6-0.9-0.90.9-0.5-0.9-0.8-0.90.50.7-0.7-0.80.5-0.70.60.60.60.7-0.30.8-0.50.1
Reaction time trials completed1.96.69.12.1-2.12.5-2.92.52.5-2.52.82.52.52.5-2.9-2.52.52.6-2.72.6-2.5-2.8-2.7-2.73.0-1.52.7-2.6
Reaction time trials AUC2.38.110.82.4-2.42.8-3.22.82.8-2.83.12.82.82.8-3.1-2.82.82.9-2.92.9-2.7-3.1-3.0-2.93.3-1.82.8-2.8
Run reversals in cocaine runway, females0.40.41.3-0.60.5-0.60.7-0.6-0.50.6-0.6-0.6-0.6-0.60.60.7-0.7-0.60.7-0.60.70.60.50.6-0.80.6-1.11.1
Run reversals in cocaine runway, males0.40.40.80.5-0.60.6-0.80.60.6-0.60.80.60.70.6-0.8-0.90.90.7-0.70.7-0.8-0.7-0.7-0.70.7-0.30.2-0.1
Latency to leave start box in cocaine runway0.10.10.7-0.30.5-0.10.1-0.1-0.10.1-0.1-0.1-0.1-0.10.00.4-0.40.00.1-0.00.6-0.0-0.1-0.20.30.30.6-0.9
Latency to leave start box in cocaine runway, F0.30.41.50.2-0.00.5-0.70.50.6-0.50.60.60.60.6-0.6-0.10.10.7-0.50.70.1-0.7-0.7-0.91.0-0.21.0-1.2
Latency to leave start box in cocaine runway, M0.20.20.2-0.40.4-0.40.5-0.4-0.40.4-0.4-0.4-0.4-0.40.40.3-0.3-0.40.5-0.40.40.40.40.4-0.40.40.1-0.1
Std. dev. time between licks in bursts0.00.10.70.5-0.40.3-0.00.20.2-0.20.00.20.20.20.0-0.20.20.1-0.30.1-0.2-0.00.1-0.1-0.2-0.80.4-0.2
Total sessions with >9 infusions3.64.45.22.3-2.02.2-2.22.22.2-2.22.32.22.22.2-2.3-2.32.32.2-2.32.2-2.2-2.2-2.2-2.21.9-1.61.1-0.9
Short access day 1 total inactive lever presses0.71.43.61.9-1.71.4-0.91.31.3-1.30.91.21.21.2-0.9-1.21.21.1-1.01.1-1.3-0.8-0.8-0.70.1-1.21.7-1.2
Short access day 10 total inactive lever presses0.21.21.5-1.11.2-1.11.2-1.1-1.11.1-1.1-1.1-1.1-1.11.10.9-0.9-1.11.0-1.20.81.21.21.2-1.21.10.3-0.4
Short access day 1 total infusions1.42.83.51.8-1.51.7-1.71.71.7-1.71.71.71.71.7-1.7-1.91.91.7-1.81.7-1.7-1.7-1.7-1.71.4-1.41.4-1.4
Short access day 10 total infusions2.84.65.92.4-2.32.3-2.32.32.3-2.32.32.32.32.3-2.3-2.32.32.2-2.22.2-2.2-2.2-2.1-2.11.8-1.70.9-0.6
Short access total infusions2.23.14.32.1-1.91.9-1.81.91.9-1.91.81.91.91.8-1.8-1.91.91.8-1.91.8-1.8-1.7-1.7-1.71.4-1.50.8-0.6
Short access day 1 locomotion2.74.56.12.5-2.42.2-2.12.22.2-2.22.12.22.22.2-2.1-2.52.52.1-2.12.1-2.4-2.0-2.0-2.01.6-2.01.3-0.9
Short access day 10 total locomotion0.00.00.2-0.10.5-0.10.0-0.1-0.10.10.0-0.1-0.1-0.1-0.0-0.00.0-0.00.1-0.0-0.00.0-0.00.0-0.00.4-0.20.1
Short access total locomotion0.60.81.41.2-0.91.0-0.91.01.0-1.01.01.01.01.0-1.0-1.11.11.0-0.91.0-1.1-0.9-0.9-0.90.5-0.50.10.0
One hour access (0.3 mA shock)0.10.10.20.5-0.30.3-0.20.30.3-0.30.20.30.30.3-0.2-0.30.30.2-0.30.2-0.2-0.1-0.1-0.1-0.0-0.20.2-0.1
Compulsive drug intake0.20.32.60.10.20.2-0.30.20.2-0.20.40.30.30.3-0.4-0.10.10.3-0.30.3-0.3-0.3-0.4-0.30.40.01.5-1.6
One hour access (shock baseline)0.61.62.31.5-1.51.3-1.21.31.3-1.31.31.31.31.3-1.2-1.51.51.2-1.31.3-1.4-1.2-1.1-1.10.9-1.30.00.2
Social response proportion0.60.81.50.9-0.60.9-1.00.90.9-0.91.00.90.90.9-1.0-0.90.90.9-0.80.9-0.9-0.9-1.0-0.91.0-1.20.2-0.0
Social responses0.70.91.10.9-0.91.0-1.01.01.0-1.01.01.01.01.0-1.1-1.01.01.0-0.91.0-1.0-1.0-1.0-1.01.0-0.90.7-0.6
Social time3.04.76.1-1.92.0-2.12.3-2.1-2.12.1-2.3-2.1-2.1-2.12.32.5-2.5-2.22.5-2.22.32.32.32.2-2.42.2-1.51.3
Soleus weight0.10.30.50.6-0.60.6-0.50.60.6-0.60.60.60.60.6-0.6-0.60.60.6-0.60.6-0.6-0.5-0.6-0.50.4-0.00.6-0.7
Bone: stiffness0.71.31.71.3-1.31.2-1.01.21.2-1.21.21.21.21.2-1.2-1.11.11.1-1.01.1-1.1-1.0-1.2-1.00.8-0.81.3-1.1
Tibialis anterior weight3.311.414.53.8-3.73.6-3.43.63.5-3.53.33.53.53.5-3.3-3.43.43.5-3.33.4-3.4-3.3-3.4-3.23.1-3.42.8-2.2
Time to tail flick, vehicle, before self-admin2.32.83.61.6-1.41.7-1.91.71.7-1.71.81.71.71.7-1.8-1.71.71.8-1.91.7-1.7-1.8-1.8-1.81.8-1.80.6-0.4
Time to tail flick, vehicle, after self-admin0.10.21.2-0.70.5-0.2-0.1-0.2-0.20.20.1-0.2-0.1-0.2-0.10.3-0.3-0.00.1-0.00.3-0.2-0.1-0.20.60.70.9-1.1
Time to tail flick, test, before self-admin0.20.30.4-0.40.5-0.60.6-0.6-0.60.6-0.6-0.6-0.6-0.60.60.2-0.2-0.60.2-0.60.20.60.60.6-0.60.5-0.0-0.1
Time to tail flick, test, after self-admin0.20.21.20.10.1-0.20.4-0.2-0.20.3-0.5-0.3-0.3-0.30.50.7-0.7-0.30.4-0.30.50.30.40.3-0.60.4-0.91.1
Delta time to tail flick, vehicle, before/after SA0.40.42.3-0.70.5-0.50.4-0.5-0.50.5-0.4-0.5-0.5-0.50.40.5-0.5-0.40.6-0.40.60.30.40.3-0.00.91.3-1.5
Delta time to tail flick, test, before/after SA0.50.71.00.9-0.91.0-0.90.91.0-0.90.90.90.90.9-0.9-0.50.50.9-0.70.9-0.6-0.9-0.8-0.90.7-0.8-0.10.4
Tibia length0.20.71.71.2-1.30.9-0.70.90.9-0.90.80.90.90.9-0.8-0.90.90.7-0.90.8-0.9-0.6-0.6-0.80.3-0.50.4-0.1
Ambulatory time before self-admin0.00.00.1-0.30.1-0.10.1-0.1-0.10.1-0.0-0.1-0.1-0.10.00.1-0.1-0.10.2-0.10.10.10.10.10.00.20.1-0.2
Ambulatory time after self-admin0.50.81.4-1.11.0-0.90.7-0.9-0.80.9-0.8-0.8-0.8-0.80.71.0-1.0-0.80.9-0.81.00.70.70.7-0.61.0-1.21.0
Bone: tissue strength0.70.81.1-0.60.8-0.81.1-0.9-0.90.9-1.0-0.9-0.9-0.91.00.9-0.9-0.90.9-0.90.91.01.01.0-1.00.80.1-0.2
Total heroin consumption0.00.00.40.1-0.20.10.00.10.0-0.1-0.00.00.00.00.0-0.30.3-0.0-0.0-0.0-0.20.10.10.1-0.2-0.20.7-0.6
Bone: trabecular number0.10.10.80.20.1-0.10.3-0.1-0.20.2-0.3-0.2-0.2-0.20.30.2-0.2-0.20.2-0.20.10.30.40.3-0.4-0.2-0.80.9
Bone: trabecular spacing0.10.10.5-0.20.10.1-0.30.10.1-0.10.30.10.10.1-0.3-0.10.10.2-0.10.2-0.0-0.3-0.4-0.20.50.30.6-0.7
Bone: trabecular thickness1.21.72.51.3-1.41.3-1.51.31.3-1.31.41.31.31.3-1.4-1.41.41.3-1.51.3-1.4-1.4-1.1-1.31.2-1.6-0.00.3
Bone: trabecular tissue density0.20.40.70.4-0.60.6-0.80.60.6-0.60.80.60.60.6-0.8-0.60.60.6-0.70.7-0.5-0.7-0.6-0.80.8-0.00.00.1
Water consumed over 24 hours0.10.30.7-0.90.7-0.60.4-0.6-0.60.6-0.5-0.6-0.6-0.60.50.5-0.5-0.50.5-0.50.50.50.50.5-0.30.8-0.30.1
Number of responses in last shaping day2.63.44.71.4-1.31.6-2.01.71.7-1.72.01.71.71.7-2.0-2.12.11.8-2.01.8-2.2-1.9-1.9-1.82.0-1.42.1-2.2