Hub : Genes

Mfsd12

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL isoform ratio XM_039079381.1 0.03 0.03 6.5e-05 0.04 0.04 0.04 0.04 9.0e-05 4.1e-05 3.3e-05 6.4e-05
2 Brain mRNA stability Mfsd12 0.11 0.07 6.7e-07 0.05 0.05 0.05 0.05 1.0e-05 1.6e-05 3.7e-05 2.1e-05
3 NAcc isoform ratio XM_039079381.1 0.02 0.02 3.2e-03 0.02 0.02 0.01 0.01 3.6e-03 4.5e-03 7.1e-03 6.3e-03
4 NAcc intron excision ratio chr7_8348590_8348690 0.02 0.02 4.4e-03 0.02 0.02 0.01 0.02 1.8e-03 4.0e-03 1.2e-02 4.2e-03
5 LHb intron excision ratio chr7_8347708_8347795 0.15 0.1 1.5e-03 0.12 0.12 0.12 0.12 1.1e-03 1.1e-03 8.0e-04 9.2e-04
6 NAcc intron excision ratio chr7_8347925_8348496 0.04 0.03 7.6e-06 0.04 0.04 0.04 0.04 1.5e-05 2.7e-05 4.4e-05 3.1e-05
7 PL mRNA stability Mfsd12 0.04 0.04 2.9e-04 0.04 0.02 0.03 0.03 6.7e-05 1.2e-03 2.2e-04 2.3e-04
8 NAcc isoform ratio XM_008765107.3 0.01 0.01 9.2e-03 0.01 0.01 0.01 0.01 1.3e-02 1.0e-02 9.2e-03 1.3e-02
9 BLA mRNA stability Mfsd12 0.06 0.05 8.5e-04 0.05 0.06 0.05 0.06 8.8e-04 5.4e-04 7.3e-04 6.3e-04
10 NAcc intron excision ratio chr7_8348860_8349298 0.02 0.01 8.9e-03 0.01 0.01 0 0.01 1.9e-02 1.4e-02 8.0e-02 3.2e-02
11 PL isoform ratio XM_008765107.3 0.06 0.04 9.7e-08 0.07 0.07 0.07 0.07 7.8e-08 3.7e-08 3.8e-08 3.6e-08
12 Brain gene expression Mfsd12 0.19 0.11 5.2e-15 0.14 0.12 0.12 0.13 6.0e-13 6.0e-11 5.0e-11 4.6e-12
13 BLA gene expression Mfsd12 0.15 0.1 1.3e-07 0.14 0.1 0.12 0.11 7.4e-08 3.0e-06 8.0e-07 1.4e-06
14 OFC gene expression Mfsd12 0.15 0.11 1.8e-03 0.07 0.06 0.01 0.05 9.8e-03 1.7e-02 1.9e-01 2.6e-02
15 IL gene expression Mfsd12 0.16 0.11 3.9e-03 0.08 0.06 0.07 0.07 5.8e-03 1.4e-02 1.1e-02 7.2e-03
16 Adipose gene expression Mfsd12 0.6 0.19 0.0e+00 0.48 0.47 0.47 0.47 1.1e-59 1.2e-57 5.3e-59 4.5e-59
17 NAcc mRNA stability Mfsd12 0.03 0.03 4.5e-03 -0 0 0.01 0 3.9e-01 1.1e-01 4.3e-02 2.4e-01
18 NAcc gene expression Mfsd12 0.16 0.09 0.0e+00 0.17 0.16 0.17 0.16 6.0e-19 9.6e-19 1.9e-19 1.8e-18
19 PL gene expression Mfsd12 0.17 0.11 0.0e+00 0.16 0.17 0.17 0.17 5.7e-17 1.6e-18 2.9e-18 2.2e-18
20 pVTA gene expression Mfsd12 0.12 0.08 3.5e-04 0.08 0.08 0.08 0.07 2.7e-04 3.5e-04 1.8e-04 4.3e-04
21 Liver gene expression Mfsd12 0.07 0.05 1.3e-05 0.02 0.04 0.04 0.03 3.7e-03 4.2e-05 7.0e-05 2.1e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.81.35.8-0.31.2-1.2-1.00.91.11.10.4-0.70.3-0.10.60.60.60.50.62.01.3-1.31.9-2.4
Area under the delay curve2.02.13.41.4-1.31.21.2-1.3-1.2-1.4-1.51.3-1.51.51.61.81.81.61.6-0.61.9-1.61.5-1.3
BMI with tail6.119.630.25.5-4.64.54.8-4.6-4.6-4.9-4.84.7-4.84.84.64.64.64.54.6-3.64.0-3.92.8-2.1
BMI without tail2.44.912.63.6-2.42.32.7-2.4-2.7-2.8-2.42.4-2.32.32.02.02.01.92.0-2.31.5-1.40.6-0.3
Body weight1.14.55.62.1-2.32.32.3-2.4-2.2-2.3-2.32.3-2.32.32.22.12.12.22.2-1.81.9-1.91.4-0.9
Weight adjusted by age0.50.63.21.8-0.70.81.0-0.8-1.2-0.9-0.70.8-0.70.60.30.20.20.40.4-1.1-0.2-0.0-0.50.5
Bone surface1.73.011.1-1.02.2-2.2-2.11.82.22.11.1-1.61.0-0.60.30.30.30.30.33.31.4-1.42.4-3.2
Bone volume1.83.011.1-1.02.2-2.2-2.11.82.22.11.1-1.61.0-0.60.30.30.30.20.33.31.3-1.42.4-3.2
Breakpoint value in progressive ratio session4.95.47.5-2.12.1-2.0-2.22.12.02.12.5-2.22.4-2.4-2.7-2.7-2.7-2.5-2.61.2-2.72.6-2.32.0
Number of licking bursts0.30.41.30.2-0.80.80.6-0.7-0.6-0.6-0.40.6-0.40.3-0.0-0.2-0.20.0-0.2-1.1-0.50.5-0.71.1
Context. condit. distance diff. score0.30.30.50.6-0.60.70.6-0.7-0.6-0.6-0.70.7-0.70.70.60.60.60.70.5-0.50.5-0.50.4-0.2
Locomotion velocity, session 10.80.92.4-0.81.3-1.3-1.21.21.31.21.0-1.11.0-0.8-0.6-0.4-0.4-0.6-0.51.50.00.10.3-0.7
Locomotion distance, session 10.50.62.3-0.40.9-1.0-0.90.90.90.90.5-0.70.5-0.30.10.20.20.00.11.50.7-0.61.1-1.4
Locomotion velocity, session 23.64.27.8-2.12.6-2.7-2.52.52.72.52.3-2.52.2-2.0-1.6-1.5-1.5-1.7-1.62.8-0.90.9-0.1-0.6
Locomotion distance, session 21.72.45.8-1.62.0-2.1-2.02.02.12.01.6-1.91.6-1.4-0.9-0.9-0.9-1.0-1.02.4-0.30.30.4-1.0
Locomotion velocity, session 35.56.47.6-2.72.6-2.5-2.52.62.52.52.8-2.72.7-2.8-2.8-2.7-2.7-2.8-2.71.8-2.52.5-2.01.5
Locomotion distance, session 30.00.00.10.10.0-0.00.10.1-0.0-0.10.1-0.00.1-0.1-0.2-0.0-0.0-0.2-0.1-0.1-0.00.2-0.30.2
Stereotopy head waving bouts, day 34.35.16.4-2.52.5-2.5-2.52.52.52.52.5-2.52.5-2.4-2.2-2.2-2.2-2.2-2.22.2-1.81.8-1.20.6
Stereotopy head waving duration, day 35.06.07.2-2.72.6-2.6-2.62.72.62.62.7-2.72.7-2.6-2.5-2.5-2.5-2.5-2.52.2-2.22.1-1.51.0
Locomotion velocity, session 70.80.81.2-1.01.0-1.1-1.11.11.11.11.0-1.11.0-1.0-0.8-0.8-0.8-0.9-0.81.0-0.60.6-0.30.1
Locomotion distance, session 70.10.20.60.4-0.50.50.6-0.4-0.5-0.6-0.30.4-0.30.20.00.10.10.00.1-0.8-0.10.2-0.50.6
Stereotopy head waving bouts, day 70.30.31.5-0.20.6-0.5-0.60.40.60.50.2-0.40.2-0.00.20.30.30.30.31.10.6-0.71.0-1.2
Stereotopy head waving duration, day 70.50.62.2-0.61.0-0.9-1.10.81.01.00.5-0.80.6-0.4-0.1-0.1-0.1-0.0-0.11.50.3-0.40.9-1.2
Locomotion velocity, session 80.91.13.7-0.91.4-1.4-1.41.21.41.40.9-1.10.9-0.7-0.3-0.3-0.3-0.2-0.31.90.2-0.41.0-1.4
Locomotion distance, session 80.10.20.5-0.40.5-0.6-0.60.50.50.50.4-0.50.4-0.3-0.1-0.2-0.2-0.2-0.20.70.0-0.00.2-0.4
Degree of sensitization distance0.30.30.50.6-0.60.60.6-0.6-0.5-0.5-0.70.6-0.60.70.70.60.60.70.6-0.40.6-0.60.5-0.4
Degree of sensitization stereotypy1.71.93.31.3-0.90.90.8-1.1-0.8-0.9-1.31.1-1.31.41.61.61.61.61.6-0.11.8-1.81.8-1.7
Conditioned locomotion1.92.24.61.6-2.02.02.0-1.8-2.0-1.8-1.61.8-1.61.41.11.01.01.11.1-2.10.5-0.5-0.10.6
Cocaine response after cond. corrected5.15.78.82.7-2.92.93.0-2.8-2.9-2.9-2.62.8-2.62.52.12.12.12.12.0-2.91.5-1.40.60.1
Cocaine response after cond. not corrected5.66.110.02.8-3.13.13.2-3.0-3.0-3.0-2.72.9-2.72.62.12.12.12.12.1-3.01.4-1.40.60.2
Cocaine response before conditioning0.50.60.9-0.81.0-0.9-0.80.90.90.90.9-0.90.8-0.8-0.7-0.7-0.7-0.7-0.60.9-0.50.4-0.2-0.0
Saline control response0.10.10.30.3-0.50.40.5-0.4-0.4-0.4-0.30.4-0.30.30.20.10.10.10.2-0.50.0-0.0-0.20.3
Bone: connectivity density0.60.94.40.30.5-0.6-0.30.30.50.4-0.1-0.1-0.20.40.91.01.00.81.01.31.5-1.41.8-2.1
Bone: cortical apparent density0.91.21.91.0-1.11.31.0-1.3-1.1-1.0-1.31.2-1.21.31.21.01.01.41.0-0.80.8-1.00.9-0.5
Bone: cortical area0.71.03.30.6-0.10.20.1-0.4-0.2-0.1-0.70.4-0.70.91.21.11.11.31.10.61.4-1.51.8-1.8
Bone: cortical porosity0.60.61.2-0.91.0-1.0-1.10.91.01.10.8-0.90.8-0.8-0.6-0.6-0.6-0.6-0.61.1-0.40.3-0.0-0.2
Bone: cortical porosity0.30.31.0-0.30.6-0.6-0.70.50.60.70.2-0.40.3-0.20.10.10.10.10.11.00.4-0.50.8-1.0
Bone: cortical thickness1.01.72.71.2-1.01.00.9-1.2-1.0-0.9-1.41.2-1.31.41.61.51.51.61.5-0.41.5-1.61.6-1.4
Bone: cortical thickness0.10.10.60.1-0.30.30.3-0.2-0.3-0.4-0.10.2-0.0-0.0-0.2-0.3-0.3-0.3-0.3-0.6-0.50.5-0.70.8
Bone: cortical tissue density0.60.81.40.8-0.91.10.9-1.2-0.9-0.8-1.11.0-1.01.10.90.80.81.20.8-0.80.6-0.80.8-0.3
Condit. Reinf. active minus inactive responses3.74.25.0-2.22.1-2.2-2.12.22.22.12.2-2.22.2-2.2-2.1-2.1-2.1-2.2-2.21.7-1.91.9-1.41.0
Condit. Reinf. active-inactive response ratio1.92.12.8-1.51.2-1.2-1.21.31.31.21.5-1.41.5-1.5-1.7-1.6-1.6-1.7-1.70.6-1.71.7-1.51.4
Condit. Reinf. active responses3.34.15.9-2.22.4-2.4-2.42.42.42.32.2-2.42.3-2.1-1.9-1.9-1.9-1.9-1.92.2-1.41.4-0.80.2
Condit. Reinf. inactive responses0.91.12.8-1.01.4-1.5-1.41.31.41.41.1-1.31.1-0.9-0.6-0.6-0.6-0.7-0.71.7-0.20.10.3-0.7
Incentive salience index mean2.12.53.9-1.71.9-1.9-1.91.92.01.81.7-1.91.8-1.6-1.4-1.4-1.4-1.4-1.51.8-1.01.0-0.50.0
Condit. Reinf. lever presses0.50.72.8-0.20.9-0.9-0.90.71.00.80.4-0.70.4-0.10.30.40.40.30.21.60.9-0.91.4-1.7
Condit. Reinf. active minus inactive responses2.22.74.1-1.71.2-1.2-1.31.41.21.31.6-1.41.6-1.8-1.9-1.9-1.9-1.9-1.90.5-2.02.0-2.01.8
Condit. Reinf. active-inactive response ratio0.50.52.6-0.2-0.40.40.3-0.2-0.4-0.40.10.10.1-0.3-0.7-0.6-0.6-0.7-0.7-1.0-1.01.1-1.51.6
Condit. Reinf. active responses2.23.03.6-1.91.7-1.7-1.71.81.71.71.9-1.81.8-1.9-1.8-1.8-1.8-1.9-1.91.2-1.71.7-1.51.1
Condit. Reinf. inactive responses1.31.62.4-1.31.5-1.6-1.51.51.51.51.4-1.51.4-1.3-1.0-1.1-1.1-1.1-1.11.4-0.80.8-0.4-0.0
Condit. Reinf. lever presses2.23.04.1-1.81.4-1.4-1.41.61.41.41.8-1.61.8-1.9-2.0-2.0-2.0-2.0-2.00.7-2.02.0-1.91.6
Condit. Reinf. lever reinforcers received1.72.33.2-1.61.3-1.4-1.41.51.31.31.6-1.51.6-1.7-1.7-1.7-1.7-1.8-1.70.8-1.71.7-1.51.3
Conditioned reinforcement - actives2.52.53.2-1.11.8-1.7-1.61.81.61.71.6-1.71.7-1.7-1.7-1.7-1.7-1.6-1.71.3-1.61.4-1.10.7
Conditioned reinforcement - inactives0.70.71.9-0.3-1.31.41.0-1.3-1.0-0.9-1.01.1-1.00.80.60.50.50.60.6-1.30.2-0.30.00.5
Conditioned locomotion7.59.010.9-3.13.0-3.0-3.03.13.03.03.3-3.23.2-3.3-3.2-3.1-3.1-3.2-3.22.2-2.92.9-2.41.8
Patch foraging indifference point 0 sec0.10.20.5-0.3-0.50.50.3-0.5-0.3-0.2-0.60.5-0.50.50.60.50.50.60.5-0.20.5-0.60.7-0.5
Patch foraging indifference point AUC0.91.01.4-0.21.1-1.1-0.81.10.90.81.1-1.11.1-1.1-1.2-1.1-1.1-1.2-1.20.6-1.11.2-1.10.8
Delay disc. indifference point, 0s delay6.57.111.82.4-2.02.01.9-2.2-1.9-1.9-2.72.3-2.62.83.13.13.13.13.1-0.53.3-3.43.4-3.1
Delay disc. indifference point, 16s delay0.10.20.40.3-0.30.30.3-0.3-0.3-0.4-0.40.3-0.30.40.40.60.60.40.4-0.10.6-0.40.4-0.4
Delay disc. indifference point, 2s delay5.25.77.82.5-2.12.02.0-2.2-2.0-2.0-2.52.3-2.52.62.72.72.72.72.7-1.02.7-2.82.6-2.3
Delay disc. indifference point, 24s delay0.60.62.21.5-0.70.60.9-0.6-0.8-1.0-0.70.7-0.70.70.71.01.00.70.8-0.60.9-0.60.4-0.4
Delay disc. indifference point, 4s delay1.11.22.71.1-0.60.50.6-0.6-0.6-0.7-0.90.7-0.91.01.31.41.41.21.30.11.7-1.51.5-1.6
Delay disc. indifference point, 8s delay1.01.01.60.7-1.21.21.2-1.2-1.2-1.3-1.11.2-1.11.01.01.11.10.91.0-1.10.9-0.70.4-0.1
Indifference point function ln k0.20.30.5-0.1-0.70.70.5-0.7-0.5-0.4-0.60.6-0.60.60.60.50.60.60.5-0.50.5-0.50.5-0.2
Indifference point function log k0.20.30.5-0.1-0.70.70.5-0.7-0.5-0.4-0.60.6-0.60.60.60.50.60.60.5-0.50.5-0.50.5-0.2
Patch foraging total patch changes 0 sec0.10.20.3-0.4-0.50.50.3-0.5-0.3-0.2-0.50.4-0.50.40.50.40.40.50.4-0.30.4-0.50.5-0.3
Patch foraging total patch changes 12 sec0.40.61.41.2-1.00.91.0-0.8-1.1-1.1-0.70.8-0.70.60.50.40.30.40.4-1.10.1-0.1-0.30.5
Patch foraging total patch changes 18 sec0.91.21.6-0.91.1-1.0-1.11.11.11.11.0-1.11.2-1.2-1.2-1.3-1.2-1.1-1.20.7-1.21.1-0.90.7
Patch foraging total patch changes 24 sec0.10.10.20.50.4-0.5-0.20.50.30.20.3-0.40.4-0.3-0.2-0.3-0.3-0.3-0.30.3-0.20.2-0.3-0.0
Patch foraging total patch changes 6 sec0.20.32.1-1.40.3-0.4-0.60.40.60.60.4-0.50.5-0.5-0.4-0.6-0.6-0.4-0.60.3-0.50.4-0.10.3
Patch foraging time to switch 0 sec1.52.24.10.9-1.11.00.8-1.1-1.0-0.9-1.51.2-1.51.51.91.81.71.71.9-0.22.0-2.02.0-1.9
Patch foraging water rate 0 sec0.30.42.20.2-0.50.50.5-0.3-0.4-0.40.10.20.0-0.2-0.5-0.6-0.5-0.5-0.7-1.0-0.91.0-1.31.5
Patch foraging water rate 12 sec1.21.84.21.7-1.71.81.9-1.7-1.8-1.8-1.31.6-1.41.30.80.70.80.90.7-2.10.2-0.2-0.30.8
Patch foraging water rate 18 sec1.01.36.40.2-0.80.80.9-0.5-0.9-0.8-0.00.40.0-0.3-0.8-1.0-0.9-0.8-1.0-1.8-1.71.6-2.12.5
Patch foraging water rate 24 sec1.31.87.10.2-1.91.91.7-1.5-1.6-1.6-0.81.3-0.90.5-0.1-0.1-0.0-0.1-0.2-2.7-0.91.0-1.72.4
Patch foraging water rate 6 sec0.71.04.2-0.5-0.10.00.10.2-0.0-0.10.6-0.20.5-0.8-1.1-1.1-1.0-1.2-1.1-0.9-1.41.6-1.92.1
Seeking ratio, delayed vs. immediate footshock4.75.47.4-2.52.6-2.7-2.62.72.72.52.6-2.62.6-2.5-2.3-2.2-2.2-2.3-2.22.2-1.81.8-1.20.7
Distance traveled before self-admin0.30.30.80.9-0.30.30.3-0.3-0.4-0.4-0.30.3-0.40.40.60.70.70.60.50.00.8-0.60.7-0.7
Distance traveled after self-admin0.91.01.6-1.01.1-1.2-1.21.21.01.01.3-1.11.1-1.1-0.9-0.8-0.8-1.0-1.01.0-0.60.8-0.50.3
Extensor digitorum longus weight4.316.822.54.4-4.74.74.6-4.6-4.6-4.7-4.54.6-4.54.43.94.14.13.93.9-4.23.3-3.01.8-0.8
Bone: elastic displacement0.30.30.4-0.60.6-0.6-0.70.60.60.70.6-0.60.6-0.6-0.6-0.5-0.5-0.5-0.50.5-0.40.4-0.30.2
Bone: elastic work0.20.20.70.3-0.10.20.0-0.3-0.1-0.0-0.40.3-0.40.40.60.60.60.60.60.20.7-0.70.8-0.8
Bone: endosteal estimation0.20.51.30.5-0.20.30.2-0.4-0.2-0.3-0.50.4-0.50.70.80.80.80.90.80.21.0-1.01.1-1.1
Bone: endosteal perimeter0.40.82.3-0.91.2-1.2-1.21.01.21.20.8-1.00.8-0.7-0.4-0.4-0.4-0.3-0.41.5-0.0-0.10.6-0.8
Epididymis fat weight0.20.41.1-0.30.3-0.2-0.20.30.10.20.6-0.40.5-0.6-0.8-0.8-0.8-0.7-0.8-0.2-1.00.9-1.01.0
Delta time in closed arm before/after self-admin1.41.44.51.5-1.51.41.8-1.2-1.6-1.6-1.11.2-0.90.70.30.30.30.20.3-2.1-0.40.4-1.21.5
Delta time in open arm before/after self-admin1.21.21.70.6-1.01.10.8-1.1-0.9-0.9-1.11.1-1.11.11.21.31.31.31.2-0.51.3-1.21.2-0.9
Diff in mean of infusions in LGA sessions1.41.62.2-1.11.3-1.2-1.21.31.21.31.5-1.31.3-1.4-1.4-1.4-1.4-1.3-1.40.8-1.31.3-1.00.8
Delay discount exponential model param1.81.93.1-1.41.2-1.2-1.21.21.21.41.4-1.31.4-1.4-1.5-1.7-1.7-1.5-1.50.6-1.71.5-1.41.2
Extinction: sum of active levers before priming1.41.43.1-0.80.6-0.5-0.60.70.60.70.9-0.81.0-1.1-1.4-1.5-1.5-1.3-1.4-0.2-1.81.6-1.71.7
Active lever presses in extinction session 63.02.93.9-1.41.9-1.8-1.91.81.71.92.0-1.81.9-1.8-1.8-1.8-1.8-1.7-1.81.4-1.61.5-1.10.8
Bone: final force1.11.83.71.2-0.70.70.7-0.9-0.7-0.8-1.21.0-1.21.41.71.61.61.71.60.11.8-1.91.9-1.9
Bone: final moment0.91.53.21.0-0.60.60.5-0.8-0.6-0.6-1.10.8-1.11.21.51.41.41.51.40.11.6-1.71.8-1.8
Food consumed during 24 hour testing period0.40.50.70.8-0.80.80.8-0.8-0.8-0.8-0.80.8-0.80.80.80.70.70.80.7-0.60.6-0.60.5-0.3
Glucose1.11.72.21.5-1.41.31.4-1.4-1.4-1.5-1.41.4-1.41.41.31.41.41.21.3-1.11.2-1.10.7-0.5
Heart weight0.40.51.4-0.20.4-0.4-0.20.50.20.20.8-0.50.6-0.7-0.9-0.8-0.8-0.9-0.8-0.1-1.01.0-1.21.1
Delay discount hyperbolic model param2.62.74.0-1.71.5-1.4-1.51.51.41.51.7-1.51.7-1.7-1.8-2.0-2.0-1.8-1.90.8-2.01.8-1.61.4
Intermittent access intake day 1-15 change6.56.410.1-3.22.3-2.2-2.52.42.52.42.5-2.52.6-2.8-2.8-2.8-2.8-2.8-2.81.5-2.72.6-2.21.9
Intermittent access intake escalation6.36.29.5-3.01.8-1.7-2.01.92.02.02.3-2.12.4-2.7-3.0-2.9-2.9-2.9-2.90.7-3.13.0-2.92.7
Intermittent access intake escalation 27.57.410.8-2.82.1-2.1-2.22.32.22.22.7-2.42.7-2.9-3.2-3.2-3.2-3.2-3.20.9-3.33.3-3.12.8
Intermitt. access day 1 inactive lever presses0.50.51.4-0.70.2-0.3-0.30.40.30.20.7-0.40.6-0.7-0.9-0.7-0.7-0.9-0.9-0.2-0.91.1-1.21.2
Intermitt. access day 15 inactive lever presses0.50.51.7-1.30.3-0.2-0.50.30.50.50.6-0.50.6-0.7-0.8-0.8-0.8-0.7-0.8-0.0-0.90.9-0.80.9
Intermitt. access escalation Index0.50.52.10.80.3-0.2-0.10.10.10.1-0.30.0-0.20.50.70.70.70.80.70.71.0-1.01.2-1.4
Intermittent access day 1 total infusions0.10.10.2-0.0-0.10.30.1-0.3-0.1-0.0-0.30.3-0.30.30.20.20.20.40.3-0.10.2-0.40.4-0.3
Intermittent access day 15 total infusions1.82.03.8-1.91.1-0.9-1.21.01.21.31.2-1.21.3-1.4-1.7-1.8-1.8-1.5-1.70.4-1.81.6-1.51.5
Intermittent access terminal intake (last 3 days)1.11.21.7-0.91.2-1.0-1.01.01.01.11.1-1.11.1-1.1-1.3-1.3-1.3-1.0-1.20.7-1.31.1-0.90.7
Intermittent access total infusions0.20.20.8-0.90.3-0.1-0.40.10.40.50.3-0.30.4-0.4-0.6-0.7-0.7-0.4-0.6-0.0-0.70.5-0.50.6
Intermittent access day 1 locomotion0.30.31.3-1.10.4-0.2-0.50.30.50.60.5-0.40.5-0.5-0.7-0.7-0.7-0.5-0.60.1-0.80.6-0.50.6
Intermittent access day 15 total locomotion3.43.67.0-2.61.7-1.5-1.81.61.81.82.0-1.81.9-2.0-2.2-2.1-2.1-2.0-2.20.9-2.12.0-1.61.6
Intermittent access total locomotion1.01.22.7-1.71.1-0.9-1.20.91.21.21.2-1.01.1-1.1-1.2-1.2-1.2-1.0-1.20.7-1.11.0-0.70.7
Intermittent access standard deviation3.03.24.5-1.71.6-1.5-1.51.61.51.51.8-1.71.8-1.9-2.1-2.1-2.1-2.0-2.10.8-2.12.0-1.91.6
Left kidney weight0.10.31.10.50.8-0.8-0.60.70.70.60.4-0.60.4-0.2-0.0-0.1-0.00.0-0.01.00.2-0.20.5-0.9
Right kidney weight1.33.85.0-1.62.2-2.2-2.12.22.12.22.2-2.22.2-2.0-1.9-2.0-2.0-1.9-2.01.8-1.71.6-1.20.6
Cocaine induced anxiety0.91.02.5-0.41.4-1.5-1.21.41.21.21.3-1.31.1-0.9-0.6-0.6-0.6-0.7-0.61.6-0.30.20.1-0.6
Post-drug Anxiety0.70.82.80.51.4-1.5-1.01.31.01.01.0-1.10.9-0.6-0.3-0.3-0.3-0.4-0.31.70.2-0.20.5-1.2
Baseline Anxiety0.10.10.40.2-0.20.20.1-0.1-0.1-0.1-0.10.10.0-0.1-0.2-0.3-0.3-0.2-0.3-0.4-0.50.4-0.50.6
Tail length2.98.711.5-3.42.7-2.6-2.82.82.72.83.1-2.93.1-3.2-3.3-3.2-3.3-3.2-3.31.7-3.23.2-2.72.3
Length with tail1.86.714.7-3.82.6-2.5-2.92.62.93.02.8-2.72.7-2.7-2.6-2.6-2.6-2.5-2.62.2-2.22.2-1.41.2
Length without tail0.20.52.5-1.60.6-0.6-0.90.61.11.00.5-0.60.4-0.3-0.0-0.1-0.00.00.01.20.3-0.41.0-0.9
Times rat made contact with spout0.30.30.90.6-0.80.70.8-0.6-0.8-0.8-0.50.6-0.50.40.30.30.30.20.3-1.00.00.0-0.30.5
Lifetime Intake0.10.10.2-0.20.3-0.1-0.30.10.30.40.2-0.20.2-0.2-0.4-0.5-0.5-0.1-0.30.1-0.50.2-0.20.2
Liver weight, left2.54.06.92.6-2.22.22.3-2.1-2.3-2.4-2.12.2-2.12.11.81.91.91.91.9-1.91.5-1.50.8-0.5
Liver weight, right1.62.63.21.7-1.51.61.6-1.7-1.6-1.7-1.71.7-1.71.81.71.71.71.71.8-1.11.6-1.61.3-1.0
Locomotor activity3.55.610.9-3.32.7-2.7-3.02.62.92.92.6-2.72.5-2.4-2.0-2.1-2.1-2.0-2.12.7-1.51.4-0.50.1
Locomotor testing distance2.03.46.0-2.52.1-2.0-2.22.02.22.22.0-2.02.0-1.9-1.7-1.8-1.8-1.6-1.71.9-1.41.2-0.60.3
Locomotor testing rearing0.00.10.20.10.10.10.0-0.0-0.0-0.10.1-0.10.1-0.1-0.3-0.3-0.3-0.2-0.3-0.2-0.40.4-0.30.4
Locomotion in novel chamber0.40.51.30.70.5-0.7-0.30.80.30.20.7-0.60.7-0.7-0.9-0.8-0.8-0.9-0.80.1-0.91.0-1.10.8
Locomotion in novel chamber post-restriction0.70.81.0-0.51.0-1.0-0.91.00.80.91.0-0.91.0-1.0-0.9-1.0-1.0-1.0-1.00.7-0.90.8-0.80.5
Fecal boli incidents, locomotor time 11.81.93.21.4-1.71.81.7-1.8-1.7-1.7-1.51.7-1.61.51.21.11.11.21.2-1.70.7-0.80.30.2
Change in fecal boli incidents, locomotor task0.70.62.1-0.61.1-1.1-1.01.01.01.10.7-0.90.7-0.6-0.3-0.4-0.4-0.3-0.31.5-0.0-0.20.6-0.9
Time >=10cm from walls, locomotor time 10.40.41.30.5-0.20.20.0-0.3-0.1-0.1-0.50.3-0.40.60.70.70.70.80.60.40.9-1.01.2-1.1
Bouts of movement, locomotor time 10.10.20.3-0.40.4-0.3-0.40.30.30.30.4-0.30.4-0.4-0.5-0.5-0.5-0.4-0.50.1-0.50.5-0.40.4
Total resting periods, locomotor time 10.20.20.3-0.50.6-0.4-0.50.40.50.50.5-0.50.5-0.5-0.5-0.5-0.5-0.4-0.60.3-0.50.4-0.30.3
Rest time, locomotor task time 10.20.20.5-0.30.6-0.4-0.70.40.50.60.5-0.50.5-0.3-0.4-0.4-0.4-0.2-0.50.6-0.40.20.1-0.1
Distance moved, locomotor task time 10.50.51.70.1-0.20.20.2-0.3-0.1-0.1-0.50.3-0.50.50.80.90.90.80.90.41.2-1.11.3-1.3
Vertical activity count, locomotor time 10.00.10.2-0.2-0.40.30.3-0.3-0.3-0.3-0.20.3-0.30.20.20.20.20.10.2-0.30.1-0.1-0.10.2
Time >=10cm from walls, locomotor time 21.01.11.71.1-1.31.21.1-1.2-1.2-1.3-1.21.2-1.11.10.91.01.00.90.8-1.20.7-0.70.3-0.0
Bouts of movement, locomotor time 20.50.61.6-0.81.0-1.0-1.00.91.01.00.8-0.90.8-0.7-0.4-0.4-0.4-0.4-0.41.30.00.00.4-0.6
Total resting periods, locomotor time 20.50.51.7-0.61.0-1.0-1.00.91.00.90.7-0.90.7-0.6-0.3-0.3-0.3-0.3-0.41.30.1-0.10.5-0.8
Rest time, locomotor task time 20.50.61.2-0.51.1-1.1-1.01.01.01.00.9-1.00.9-0.8-0.6-0.6-0.6-0.6-0.71.1-0.30.30.0-0.3
Distance moved, locomotor task time 20.80.91.70.6-1.31.31.1-1.2-1.1-1.1-1.11.1-1.11.00.80.80.80.80.8-1.30.5-0.50.20.2
Vertical activity count, locomotor time 20.91.02.40.7-1.41.41.2-1.3-1.3-1.2-1.01.2-1.10.90.60.50.50.70.5-1.60.1-0.2-0.20.7
Light reinforcement 15.29.514.5-3.83.1-3.2-3.33.33.43.33.3-3.33.3-3.4-3.1-3.1-3.1-3.2-3.12.5-2.72.8-2.01.5
Light reinforcement 21.72.35.8-2.41.5-1.4-1.71.51.71.81.5-1.51.6-1.6-1.5-1.5-1.5-1.4-1.51.3-1.31.3-0.80.7
Bone: marrow area0.20.51.30.5-0.20.30.2-0.4-0.2-0.3-0.60.4-0.60.70.80.80.80.90.80.21.0-1.01.1-1.1
Bone: maximum diameter0.81.64.0-1.41.7-1.6-1.81.51.71.71.2-1.51.3-1.0-0.7-0.8-0.8-0.6-0.82.0-0.30.10.5-0.9
Bone: maximum force1.11.93.51.3-0.90.90.8-1.1-0.9-0.9-1.41.1-1.31.51.71.61.61.81.6-0.21.8-1.81.9-1.7
Bone: maximum moment0.91.63.11.1-0.80.80.7-1.0-0.8-0.8-1.21.0-1.21.41.61.51.51.61.5-0.11.6-1.71.8-1.6
Mean time between licks in bursts3.65.16.5-2.42.1-2.0-2.12.12.12.12.4-2.22.4-2.4-2.5-2.6-2.6-2.5-2.61.2-2.52.5-2.21.9
Mean num. licks in bursts0.10.10.30.20.1-0.2-0.00.20.00.0-0.0-0.1-0.00.00.20.30.30.10.30.30.4-0.30.3-0.6
Cd content in liver0.20.20.30.4-0.30.30.3-0.4-0.3-0.3-0.40.4-0.40.40.50.50.50.40.5-0.20.5-0.50.4-0.4
Co content in liver0.60.71.1-1.00.5-0.6-0.70.70.60.60.8-0.70.8-0.9-0.9-0.9-0.9-1.0-0.90.2-0.91.0-1.00.9
Cu content in liver0.30.31.4-0.10.2-0.2-0.30.10.30.2-0.1-0.1-0.10.20.50.60.60.50.50.80.9-0.81.1-1.2
Fe content in liver0.10.10.40.1-0.20.20.2-0.1-0.2-0.1-0.00.10.0-0.1-0.2-0.3-0.3-0.2-0.2-0.5-0.50.4-0.60.6
K content in liver0.30.21.1-0.20.5-0.5-0.50.50.50.40.2-0.40.2-0.10.20.30.30.20.20.90.6-0.50.8-1.0
Mg content in liver0.30.41.60.00.7-0.6-0.60.60.60.50.2-0.40.2-0.10.20.40.40.20.21.10.7-0.61.0-1.3
Mn content in liver1.82.16.7-1.12.0-2.0-2.01.81.92.01.3-1.71.3-1.1-0.5-0.5-0.5-0.5-0.52.60.3-0.31.0-1.7
Na content in liver0.91.01.90.8-0.70.70.5-0.8-0.7-0.5-1.00.8-0.91.01.21.21.21.21.2-0.11.4-1.31.3-1.3
Rb content in liver0.60.72.70.60.10.1-0.0-0.1-0.0-0.0-0.50.2-0.40.70.90.90.91.00.90.71.3-1.31.5-1.6
Se content in liver0.20.20.5-0.40.5-0.7-0.50.60.50.50.5-0.50.5-0.5-0.4-0.4-0.4-0.6-0.40.5-0.30.3-0.20.0
Sr content in liver0.30.31.30.1-0.50.30.4-0.3-0.5-0.4-0.10.3-0.1-0.1-0.3-0.3-0.3-0.4-0.3-0.9-0.60.6-1.01.1
Zn content in liver2.12.46.1-1.20.7-0.7-0.61.00.60.51.3-1.01.3-1.5-1.9-1.8-1.8-2.0-1.9-0.4-2.12.3-2.52.4
Bone: minimum diameter0.10.21.1-0.10.4-0.4-0.40.20.40.40.0-0.20.10.10.30.30.30.40.30.80.5-0.61.0-1.0
Time in familiar zone, hab. session 12.01.82.5-1.41.2-1.2-1.11.31.21.21.4-1.31.4-1.5-1.5-1.6-1.6-1.6-1.50.7-1.51.5-1.41.1
Time in novel zone, hab. session 11.01.02.60.8-0.50.50.4-0.6-0.4-0.4-0.90.6-0.81.01.21.21.21.21.10.31.4-1.41.6-1.6
Total zone transitions, hab. session 11.01.43.4-1.21.6-1.6-1.61.51.51.61.3-1.41.3-1.1-0.7-0.7-0.7-0.8-0.81.8-0.30.20.3-0.7
Total locomotion distance, hab. session 11.62.26.6-1.42.0-2.1-2.01.92.02.01.5-1.81.4-1.2-0.6-0.6-0.6-0.8-0.62.60.1-0.10.9-1.5
Locomotion velocity, hab. session 11.72.45.7-1.62.1-2.1-2.02.02.02.01.7-1.91.6-1.5-1.0-1.0-1.0-1.1-1.02.4-0.30.30.3-1.0
Time in familiar zone, hab. session 25.75.98.0-2.52.1-2.1-2.02.32.12.02.5-2.32.5-2.6-2.8-2.8-2.8-2.8-2.71.0-2.82.8-2.62.3
Time in novel zone, hab. session 24.24.26.42.0-1.61.61.5-1.8-1.6-1.6-2.11.8-2.02.22.42.42.42.42.4-0.62.5-2.52.5-2.2
Total zone transitions, hab. session 20.50.73.50.30.2-0.4-0.30.20.30.3-0.2-0.1-0.20.40.90.80.80.70.81.01.3-1.31.6-1.9
Total locomotion distance, hab. session 20.91.22.7-1.11.4-1.6-1.41.51.41.41.2-1.31.2-1.1-0.7-0.7-0.7-0.9-0.71.6-0.30.30.2-0.7
Locomotion velocity, hab. session 21.01.33.5-1.11.5-1.7-1.51.51.51.51.2-1.41.2-1.1-0.6-0.6-0.6-0.7-0.61.9-0.10.00.4-1.0
Novel to familiar place preference ratio3.73.86.51.9-1.31.31.3-1.5-1.3-1.4-1.81.6-1.82.02.22.32.32.32.3-0.32.6-2.52.5-2.4
Novelty place preference2.22.34.41.4-0.90.90.9-1.1-0.9-1.0-1.31.1-1.41.51.71.91.91.81.80.02.1-2.02.1-2.0
Time in novel zone, NPP test2.52.64.71.6-1.01.01.1-1.2-1.0-1.1-1.51.3-1.51.71.82.02.01.91.9-0.22.2-2.12.1-2.0
Total zone transitions, NPP test0.10.10.80.00.2-0.3-0.20.20.20.3-0.0-0.10.00.10.40.30.30.20.30.60.5-0.60.7-0.9
Total locomotion distance, NPP test0.20.31.70.10.3-0.5-0.30.30.30.30.0-0.20.00.10.50.50.50.30.50.90.8-0.81.0-1.3
Locomotion velocity, NPP test0.20.31.2-0.20.6-0.7-0.60.60.60.60.3-0.50.3-0.20.20.20.20.00.21.00.5-0.50.8-1.1
Intraocular pressure0.40.52.10.8-0.40.30.7-0.2-0.6-0.8-0.00.2-0.0-0.1-0.5-0.4-0.4-0.6-0.4-1.1-0.91.0-1.41.4
Delta distance traveled before/after self-admin1.51.63.5-1.91.3-1.3-1.31.31.41.31.4-1.31.3-1.4-1.3-1.3-1.3-1.3-1.31.0-1.11.1-0.80.6
Delta ambulatory time before/after self-admin1.61.82.5-1.31.6-1.6-1.51.61.51.51.5-1.51.5-1.4-1.3-1.3-1.3-1.3-1.31.3-1.11.0-0.70.3
Parametrial fat weight0.50.92.2-1.50.7-0.6-0.80.70.90.81.1-0.80.9-0.9-1.1-1.0-1.1-1.0-1.00.4-1.01.0-0.80.9
Pavlov. Cond. lever latency0.20.31.50.0-0.50.50.4-0.4-0.5-0.4-0.10.3-0.1-0.1-0.3-0.4-0.4-0.3-0.4-0.9-0.70.7-1.01.2
Pavlov. Cond. magazine entry latency2.43.24.1-1.91.7-1.7-1.71.71.71.71.9-1.81.9-1.9-1.9-2.0-2.0-1.9-2.01.1-1.91.8-1.51.3
Pavlov. Cond. change in total contacts0.10.10.1-0.20.3-0.3-0.30.30.30.30.3-0.30.3-0.3-0.2-0.2-0.2-0.3-0.20.3-0.10.1-0.1-0.0
Pavlov. Cond. index score0.40.51.2-0.70.9-1.0-0.90.91.00.90.8-0.90.8-0.7-0.5-0.5-0.5-0.5-0.51.1-0.20.20.1-0.4
Pavlov. Cond. latency score0.50.61.8-0.81.1-1.1-1.11.01.11.10.8-0.90.8-0.6-0.4-0.4-0.4-0.4-0.41.4-0.0-0.00.4-0.7
Pavlov. Cond. lever contacts0.40.51.7-0.30.8-0.8-0.70.70.80.70.4-0.60.4-0.20.10.20.20.10.21.30.6-0.61.0-1.3
Pavlov. Cond. magazine entry number0.50.70.80.9-0.80.80.8-0.9-0.8-0.8-0.90.9-0.90.90.80.90.90.80.9-0.60.8-0.80.6-0.4
Pavlov. Cond. intertrial magazine entries0.20.21.1-0.2-0.20.10.1-0.0-0.2-0.10.1-0.00.2-0.3-0.4-0.6-0.6-0.5-0.6-0.5-0.80.8-0.91.0
Pavlov. Cond. lever-magazine prob. diff.0.70.91.5-1.01.2-1.2-1.21.11.21.11.0-1.11.0-0.9-0.8-0.8-0.8-0.8-0.81.2-0.50.5-0.1-0.2
Pavlov. Cond. response bias0.91.11.3-1.11.1-1.1-1.11.21.11.11.2-1.21.2-1.1-1.1-1.1-1.1-1.1-1.10.9-1.00.9-0.70.5
Pavlov. Cond. lever latency0.91.21.51.2-1.21.21.2-1.2-1.1-1.2-1.21.2-1.21.21.11.11.11.11.0-1.00.9-0.90.7-0.4
Pavlov. Cond. magazine entry latency0.50.61.1-0.91.0-0.9-1.00.91.00.80.9-0.90.9-0.8-0.8-0.7-0.7-0.6-0.70.9-0.50.5-0.10.0
Pavlov. Cond. change in total contacts0.81.21.5-1.11.1-1.1-1.11.11.01.01.2-1.11.2-1.2-1.2-1.1-1.1-1.2-1.10.7-1.01.1-1.00.7
Pavlov. Cond. index score0.91.21.5-1.21.2-1.1-1.21.21.11.11.2-1.21.2-1.2-1.2-1.1-1.1-1.1-1.10.9-1.01.0-0.70.5
Pavlov. Cond. latency score0.91.11.5-1.21.2-1.1-1.21.11.21.21.2-1.21.2-1.1-1.1-1.0-1.0-1.0-1.01.1-0.80.8-0.50.3
Pavlov. Cond. lever contacts0.81.01.4-1.11.0-1.0-0.91.00.90.91.1-1.01.1-1.1-1.2-1.1-1.1-1.2-1.10.6-1.11.1-1.00.8
Pavlov. Cond. magazine entry number0.91.11.71.1-1.31.21.3-1.2-1.3-1.1-1.21.2-1.21.11.00.90.90.91.0-1.20.6-0.70.3-0.1
Pavlov. Cond. intertrial magazine entries0.50.61.40.7-1.21.10.9-1.0-0.9-0.9-0.90.9-0.80.70.70.40.40.60.4-1.20.1-0.2-0.10.4
Pavlov. Cond. lever-magazine prob. diff.1.01.21.6-1.21.3-1.2-1.31.21.21.21.2-1.21.2-1.2-1.2-1.1-1.1-1.1-1.11.1-0.90.9-0.60.4
Pavlov. Cond. response bias1.82.43.2-1.61.5-1.5-1.51.61.41.41.7-1.61.7-1.7-1.8-1.7-1.7-1.7-1.71.0-1.61.6-1.41.1
Time in closed arm before self-admin0.91.02.9-0.0-0.50.50.3-0.6-0.3-0.3-0.70.7-0.90.91.21.21.21.21.30.31.4-1.51.7-1.5
Time in closed arm after self-admin0.00.00.10.3-0.0-0.20.20.2-0.1-0.00.1-0.10.1-0.1-0.0-0.1-0.1-0.3-0.1-0.1-0.20.2-0.40.2
Time in open arm before self-admin1.01.11.6-0.70.9-1.0-0.91.10.90.81.2-1.01.1-1.2-1.2-1.1-1.1-1.3-1.20.5-1.11.2-1.21.0
Time in open arm after self-admin0.60.71.30.4-1.01.10.8-1.1-0.8-0.9-0.91.0-0.90.90.80.90.90.90.8-0.80.8-0.70.6-0.2
Bone: periosteal estimation0.51.03.60.5-0.00.1-0.1-0.3-0.0-0.0-0.60.3-0.60.81.21.11.11.31.10.81.4-1.51.9-1.9
Bone: periosteal perimeter0.30.62.2-0.51.0-0.9-1.00.71.01.00.4-0.70.5-0.20.10.00.00.20.01.50.5-0.61.1-1.3
Bone: post-yield work0.60.81.10.9-0.91.00.8-1.0-0.9-0.9-1.01.0-1.01.01.00.80.81.00.8-0.70.7-0.80.7-0.4
Progressive ratio test 1 active lever presses0.10.20.40.2-0.50.70.5-0.6-0.5-0.4-0.40.5-0.50.40.20.10.10.30.2-0.7-0.1-0.1-0.10.3
Progressive ratio test 1 breakpoint0.20.20.40.5-0.50.70.6-0.6-0.6-0.5-0.40.6-0.50.50.30.20.20.50.3-0.60.1-0.20.10.1
Progressive ratio test 1 inactive lever presses0.00.00.1-0.40.1-0.0-0.10.00.10.20.1-0.10.1-0.1-0.1-0.1-0.1-0.0-0.10.1-0.10.00.00.0
Progressive ratio test 2 active lever presses0.30.30.7-0.10.3-0.2-0.20.30.20.20.4-0.30.4-0.5-0.7-0.7-0.7-0.6-0.7-0.1-0.80.7-0.80.8
Progressive ratio test 2 breakpoint0.30.30.5-0.10.7-0.6-0.50.60.50.50.6-0.60.6-0.6-0.7-0.7-0.7-0.6-0.70.4-0.70.6-0.50.4
Progressive ratio test 2 inactive lever presses0.10.10.2-0.30.4-0.2-0.30.20.30.40.3-0.30.3-0.2-0.3-0.3-0.3-0.1-0.20.3-0.30.1-0.00.0
Incentive Sensitization - Responses0.40.40.90.20.5-0.4-0.20.50.20.20.5-0.50.6-0.6-0.8-0.7-0.7-0.7-0.8-0.0-0.80.9-0.90.8
Incentive Sensitization - Breakpoint0.40.40.80.30.6-0.6-0.30.60.30.30.6-0.60.7-0.6-0.8-0.7-0.7-0.8-0.80.2-0.80.8-0.90.7
Sum of active levers in priming session hrs 5-60.00.00.1-0.1-0.10.2-0.1-0.1-0.10.0-0.10.1-0.00.0-0.1-0.1-0.10.0-0.1-0.1-0.20.1-0.10.2
Progressive ratio0.30.41.91.4-0.50.50.9-0.5-0.8-0.9-0.50.6-0.50.50.20.40.40.20.4-0.80.2-0.1-0.40.3
Food seeking constrained by brief footshock0.10.10.30.10.3-0.5-0.20.50.30.20.4-0.30.3-0.4-0.2-0.3-0.3-0.5-0.30.2-0.20.3-0.50.2
Seeking ratio, punishment vs. effort0.20.21.5-1.20.3-0.4-0.70.40.60.70.4-0.40.4-0.5-0.1-0.3-0.3-0.3-0.30.5-0.20.10.1-0.1
Retroperitoneal fat weight0.41.33.00.0-1.61.71.2-1.7-1.2-1.2-1.21.4-1.31.21.11.01.01.21.0-1.40.7-0.80.60.1
Reaction time number correct0.71.02.71.4-1.41.31.5-1.2-1.4-1.3-1.01.2-1.00.90.60.50.50.60.5-1.70.0-0.1-0.40.7
Reaction time mean minus median0.70.91.5-0.51.2-1.1-0.91.11.00.91.0-1.11.1-0.9-1.0-1.0-1.0-0.8-1.10.9-0.90.9-0.50.3
Reaction time mean minus median AUC0.40.51.90.30.9-0.7-0.60.50.80.60.3-0.60.30.00.10.20.30.40.21.30.6-0.71.1-1.4
Reaction time num false alarms0.10.10.40.7-0.30.30.4-0.3-0.4-0.4-0.30.3-0.20.20.10.10.10.00.0-0.5-0.10.1-0.30.4
Reaction time num false alarms AUC0.20.30.91.0-0.60.60.7-0.5-0.7-0.7-0.50.5-0.40.30.10.10.10.10.1-0.9-0.20.2-0.50.6
Reaction time trials correct on left0.71.02.71.4-1.41.31.5-1.2-1.4-1.3-1.01.2-1.00.90.60.50.50.60.5-1.70.0-0.1-0.40.7
Reaction time trials on left0.71.02.51.4-1.31.31.4-1.2-1.4-1.2-1.01.2-1.00.90.60.50.50.60.5-1.60.1-0.1-0.30.7
Reaction time mean0.20.31.20.30.6-0.4-0.30.30.40.30.1-0.30.10.10.30.20.30.40.20.90.5-0.61.0-1.1
Reaction time mean AUC0.20.31.30.20.5-0.3-0.30.20.40.20.0-0.20.00.20.40.30.30.50.30.80.6-0.71.0-1.1
Median of all reaction times0.40.51.90.60.00.10.1-0.2-0.1-0.2-0.40.2-0.40.60.80.80.80.90.70.51.0-1.11.4-1.4
Reaction time omissions0.20.30.6-0.60.7-0.6-0.70.60.80.70.5-0.70.6-0.5-0.5-0.5-0.5-0.4-0.60.7-0.40.3-0.1-0.0
Reaction time false alarm rate0.00.00.10.40.1-0.1-0.00.0-0.0-0.0-0.20.0-0.00.10.10.10.10.10.10.10.1-0.10.1-0.2
Reaction time premature initiation rate1.01.43.2-1.80.5-0.6-0.90.70.80.91.2-0.81.0-1.2-1.3-1.4-1.4-1.3-1.40.1-1.51.5-1.41.5
Reaction time premature initiations0.81.14.1-1.2-0.10.1-0.20.10.10.20.7-0.30.6-0.9-1.1-1.3-1.2-1.1-1.3-0.8-1.61.5-1.82.0
Std. dev. reaction times0.30.41.00.11.0-0.8-0.60.70.80.70.6-0.80.7-0.4-0.5-0.5-0.4-0.2-0.51.0-0.30.20.1-0.4
Reaction time trials completed0.71.02.51.4-1.31.31.4-1.2-1.4-1.2-1.01.2-1.00.90.60.50.50.60.5-1.60.1-0.1-0.30.7
Reaction time trials AUC0.71.13.01.4-1.41.41.5-1.2-1.4-1.3-1.01.2-1.00.90.50.40.40.50.4-1.7-0.10.1-0.60.9
Run reversals in cocaine runway, females0.70.61.7-0.11.1-1.3-0.81.30.90.81.0-1.00.9-0.9-0.5-0.5-0.5-0.8-0.51.1-0.20.4-0.2-0.3
Run reversals in cocaine runway, males1.21.22.3-0.61.4-1.5-1.21.51.11.31.3-1.31.2-1.2-0.9-1.0-1.0-1.1-1.01.3-0.70.7-0.5-0.1
Latency to leave start box in cocaine runway1.31.43.4-1.41.6-1.5-1.71.31.61.71.2-1.41.2-1.0-0.8-0.8-0.8-0.5-0.91.8-0.40.20.5-0.7
Latency to leave start box in cocaine runway, F0.70.73.2-0.11.0-0.9-1.00.60.81.00.3-0.60.3-0.00.40.20.20.50.21.60.7-1.01.6-1.8
Latency to leave start box in cocaine runway, M2.72.64.3-1.61.2-1.1-1.21.21.21.21.5-1.41.6-1.6-2.0-1.9-1.9-1.8-1.90.4-2.12.1-1.91.9
Std. dev. time between licks in bursts0.91.12.3-1.21.3-1.3-1.41.31.41.41.1-1.31.1-1.0-0.7-0.8-0.8-0.7-0.81.5-0.40.30.2-0.5
Total sessions with >9 infusions0.20.20.60.80.6-0.5-0.30.40.30.40.2-0.30.20.00.1-0.0-0.00.20.10.70.1-0.40.5-0.8
Short access day 1 total inactive lever presses0.00.00.1-0.00.2-0.1-0.10.10.10.20.1-0.10.2-0.2-0.2-0.3-0.3-0.2-0.20.0-0.40.2-0.20.2
Short access day 10 total inactive lever presses0.10.20.7-0.6-0.20.20.0-0.1-0.0-0.10.2-0.00.1-0.3-0.4-0.3-0.3-0.4-0.4-0.4-0.50.6-0.70.9
Short access day 1 total infusions0.30.30.90.10.9-0.7-0.60.60.60.80.4-0.60.4-0.2-0.2-0.3-0.30.0-0.10.9-0.1-0.20.5-0.7
Short access day 10 total infusions0.00.00.40.60.20.00.0-0.0-0.00.1-0.1-0.00.10.0-0.2-0.3-0.30.1-0.2-0.1-0.40.1-0.10.1
Short access total infusions0.10.11.01.00.5-0.3-0.10.20.10.20.1-0.20.10.1-0.0-0.1-0.10.20.00.4-0.1-0.20.3-0.5
Short access day 1 locomotion1.01.14.2-2.11.1-0.9-1.40.91.41.50.9-1.01.0-1.0-0.9-1.0-1.0-0.7-0.91.1-0.70.50.00.0
Short access day 10 total locomotion4.04.57.2-2.71.8-1.7-2.01.82.02.02.1-2.02.1-2.3-2.4-2.5-2.5-2.3-2.41.0-2.52.3-1.91.8
Short access total locomotion1.01.01.5-1.21.2-1.0-1.11.01.11.21.1-1.01.0-1.0-1.1-1.1-1.1-0.8-1.00.9-1.00.8-0.40.3
One hour access (0.3 mA shock)0.20.20.4-0.2-0.50.70.4-0.7-0.4-0.3-0.70.6-0.50.50.40.30.30.50.4-0.50.2-0.40.4-0.1
Compulsive drug intake0.90.91.60.5-0.90.70.7-0.7-0.7-0.7-1.00.9-0.90.91.21.21.20.91.2-0.31.3-1.11.0-0.9
One hour access (shock baseline)0.10.10.6-0.6-0.10.3-0.0-0.20.00.10.00.10.1-0.1-0.4-0.5-0.5-0.2-0.4-0.4-0.60.5-0.50.8
Social response proportion0.60.61.2-0.61.1-1.1-0.91.00.80.91.0-0.90.9-0.8-0.7-0.6-0.7-0.8-0.61.0-0.40.4-0.3-0.1
Social responses7.19.113.4-2.93.6-3.7-3.33.63.33.33.5-3.43.3-3.2-3.0-2.8-2.9-3.0-2.83.1-2.32.3-1.50.6
Social time0.70.91.30.7-1.11.11.1-1.1-1.0-1.1-1.01.1-1.01.00.90.90.90.90.9-1.00.7-0.70.5-0.2
Soleus weight8.224.028.65.3-4.95.15.1-5.1-5.0-4.9-5.35.2-5.35.45.25.25.25.35.2-3.84.7-4.63.6-2.6
Bone: stiffness2.74.36.12.1-1.81.71.7-1.9-1.8-1.7-2.22.0-2.22.32.52.32.32.42.3-0.92.4-2.42.2-1.9
Tibialis anterior weight0.93.14.42.0-1.71.71.7-1.7-1.7-2.0-1.81.8-1.91.91.82.12.11.81.9-1.22.0-1.71.3-1.1
Time to tail flick, vehicle, before self-admin0.80.82.5-0.41.4-1.4-1.11.31.21.10.9-1.11.0-0.8-0.5-0.4-0.4-0.5-0.41.6-0.00.00.3-0.8
Time to tail flick, vehicle, after self-admin0.30.31.20.8-0.20.10.40.1-0.4-0.40.30.00.1-0.2-0.4-0.5-0.5-0.6-0.4-0.7-0.70.8-1.11.0
Time to tail flick, test, before self-admin0.50.51.60.71.0-1.0-0.60.90.70.80.6-0.70.5-0.3-0.1-0.2-0.2-0.1-0.01.30.1-0.30.6-1.1
Time to tail flick, test, after self-admin0.20.20.70.10.9-0.8-0.40.70.60.60.5-0.60.5-0.4-0.3-0.3-0.3-0.2-0.30.8-0.10.00.2-0.5
Delta time to tail flick, vehicle, before/after SA1.01.03.11.2-1.41.31.3-1.1-1.4-1.3-0.81.1-0.90.70.40.30.30.30.4-1.8-0.20.2-0.71.1
Delta time to tail flick, test, before/after SA0.20.21.0-0.7-0.10.10.1-0.0-0.0-0.10.1-0.00.2-0.3-0.5-0.4-0.4-0.5-0.5-0.5-0.60.7-0.81.0
Tibia length0.82.33.5-1.91.4-1.3-1.51.41.51.51.6-1.51.6-1.6-1.8-1.7-1.7-1.6-1.70.9-1.61.6-1.31.2
Ambulatory time before self-admin0.20.20.40.6-0.30.40.3-0.4-0.4-0.4-0.30.4-0.40.40.40.60.60.50.4-0.10.6-0.50.5-0.4
Ambulatory time after self-admin0.50.51.0-0.70.8-0.8-1.00.80.70.71.0-0.80.8-0.8-0.7-0.6-0.6-0.7-0.80.7-0.40.6-0.30.2
Bone: tissue strength1.71.62.51.2-1.11.21.0-1.3-1.1-1.1-1.41.3-1.31.51.51.41.41.61.4-0.61.3-1.41.3-1.0
Total heroin consumption1.82.12.9-0.81.7-1.6-1.71.61.41.61.7-1.61.6-1.5-1.5-1.6-1.6-1.4-1.51.3-1.41.3-1.00.6
Bone: trabecular number1.01.64.4-1.21.8-1.9-1.61.71.81.61.4-1.51.3-1.1-0.7-0.6-0.6-0.8-0.62.10.00.00.5-1.1
Bone: trabecular spacing1.31.75.91.0-1.71.71.6-1.5-1.7-1.7-1.01.3-1.00.70.10.10.10.10.1-2.4-0.60.7-1.41.9
Bone: trabecular thickness1.92.29.4-0.51.6-1.6-1.51.21.61.60.6-1.00.5-0.20.70.70.70.60.72.71.6-1.72.5-3.1
Bone: trabecular tissue density2.23.15.61.7-2.22.41.9-2.3-2.2-1.9-2.12.1-1.91.91.61.41.41.81.4-2.10.9-1.00.60.2
Water consumed over 24 hours0.60.71.90.6-0.30.30.3-0.4-0.3-0.3-0.60.5-0.60.81.01.01.01.01.00.31.2-1.21.4-1.4
Number of responses in last shaping day0.20.20.4-0.60.5-0.4-0.50.40.50.70.6-0.40.4-0.4-0.4-0.6-0.6-0.3-0.40.4-0.50.3-0.20.1