Hub : Genes

Mettl25

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr7_41129348_41132822 0.08 0.05 3.6e-03 0.01 0 0 0 6.8e-03 1.1e-01 1.2e-01 7.2e-02
2 IL intron excision ratio chr7_41129348_41132471 0.32 0.15 3.6e-03 0.03 0.04 0.04 0.04 7.3e-02 3.5e-02 3.7e-02 4.3e-02
3 BLA mRNA stability Mettl25 0.23 0.09 1.4e-06 0.02 0.08 0.07 0.06 3.2e-02 3.2e-05 1.4e-04 2.4e-04
4 pVTA intron excision ratio chr7_41135754_41142747 0.31 0.13 5.8e-03 -0 0.05 0.04 -0 6.7e-01 3.8e-03 6.3e-03 5.3e-01
5 Liver isoform ratio NM_001108089.1 0.05 0.03 1.6e-04 0.03 0.03 0.03 0.03 1.9e-04 4.2e-04 2.3e-04 2.5e-04
6 Adipose intron excision ratio chr7_41129348_41132822 0.04 0.02 5.5e-03 0.01 0.01 0.01 0.02 8.4e-03 1.1e-02 8.3e-03 4.3e-03
7 Brain isoform ratio NM_001108089.1 0.03 0.02 7.8e-03 0.02 0.02 0.01 0.01 9.2e-03 4.2e-03 5.1e-02 5.6e-02
8 Liver mRNA stability Mettl25 0.16 0.07 1.3e-07 0.03 0.08 0.08 0.07 2.0e-04 3.5e-09 3.8e-09 1.5e-08
9 Liver intron excision ratio chr7_41129348_41132822 0.04 0.03 2.5e-04 0.03 0.02 0.02 0.03 1.1e-04 2.4e-03 3.0e-03 6.0e-04
10 LHb isoform ratio XM_039079103.1 0.38 0.15 6.4e-03 0.11 0.11 0.09 0.1 1.5e-03 1.5e-03 4.2e-03 2.2e-03
11 Liver isoform ratio XM_039079101.1 0.06 0.05 1.6e-03 0.03 0.02 0.03 0.02 8.1e-04 1.4e-03 2.4e-04 9.9e-04
12 Brain gene expression Mettl25 0.21 0.09 1.7e-06 0.07 0.05 0.07 0.07 3.9e-07 8.3e-06 4.6e-07 7.8e-07
13 Liver intron excision ratio chr7_41132063_41132822 0.03 0.02 7.6e-03 0.02 0.01 0.01 0.01 5.8e-03 2.6e-02 2.8e-02 3.8e-02
14 Brain mRNA stability Mettl25 0.4 0.1 0.0e+00 0.11 0.21 0.22 0.24 1.3e-10 1.2e-19 1.5e-20 7.6e-22
15 NAcc mRNA stability Mettl25 0.1 0.04 1.6e-07 0.08 0.07 0.06 0.08 3.8e-09 1.6e-08 6.2e-08 3.7e-09
16 BLA gene expression Mettl25 0.19 0.11 2.4e-03 0.01 -0 0.01 0.01 8.0e-02 3.5e-01 8.5e-02 8.5e-02
17 PL gene expression Mettl25 0.05 0.03 2.4e-03 0.03 0.02 0.01 0.02 3.7e-04 4.9e-03 2.0e-02 4.3e-03
18 NAcc gene expression Mettl25 0.07 0.04 2.0e-04 0.01 0.02 0.03 0.01 4.1e-02 1.6e-03 6.6e-04 9.3e-03
19 PL mRNA stability Mettl25 0.19 0.07 1.7e-10 0.09 0.1 0.1 0.1 2.3e-10 1.4e-11 7.2e-11 1.2e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.40.74.9-0.7-0.40.5-2.2-0.8-0.10.60.2-0.90.41.21.10.8-0.6-0.50.50.51.1-1.0
Area under the delay curve1.61.75.3-1.61.91.60.5-0.82.30.91.4-0.4-0.5-0.20.00.51.41.5-1.5-1.5-2.00.8
BMI with tail1.13.67.62.5-2.0-1.61.92.3-2.4-2.8-1.22.62.7-2.0-2.6-2.4-0.6-0.00.00.0-0.50.6
BMI without tail1.42.87.61.4-0.8-0.10.72.2-1.3-2.70.22.22.5-1.9-2.8-2.11.11.2-1.3-1.3-1.31.4
Body weight0.31.43.21.3-1.2-1.31.81.5-0.8-1.3-1.01.71.2-1.8-1.6-1.5-0.4-0.40.40.4-0.3-0.2
Weight adjusted by age0.10.10.50.3-0.5-0.20.20.0-0.3-0.1-0.3-0.10.70.20.20.10.2-0.30.30.3-0.3-0.2
Bone surface0.61.13.10.11.01.8-1.4-1.10.01.01.3-1.20.61.30.91.40.91.0-0.9-0.9-0.60.6
Bone volume0.50.84.4-0.10.21.2-2.1-1.0-0.20.90.8-1.20.71.41.11.30.20.3-0.3-0.30.3-0.3
Breakpoint value in progressive ratio session1.11.24.2-0.9-0.7-1.10.00.31.10.5-1.6-0.2-0.2-0.30.70.0-1.7-1.61.61.61.1-2.0
Number of licking bursts0.20.30.7-0.60.80.60.00.30.6-0.10.50.3-0.2-0.7-0.6-0.10.80.6-0.6-0.6-0.50.5
Context. condit. distance diff. score2.12.57.7-2.31.21.5-2.8-2.01.41.22.1-1.6-2.01.81.21.61.01.2-1.2-1.20.50.4
Locomotion velocity, session 12.32.55.71.0-1.6-2.12.02.4-0.6-2.1-1.62.40.8-2.3-1.8-2.3-0.7-0.80.80.80.1-0.3
Locomotion distance, session 12.22.87.91.3-1.3-1.51.72.5-1.1-2.8-0.72.61.4-2.3-2.5-2.60.40.4-0.4-0.4-0.70.9
Locomotion velocity, session 21.31.53.31.1-0.10.10.91.4-0.8-1.80.51.31.3-1.0-1.6-1.31.41.2-1.2-1.2-1.51.6
Locomotion distance, session 22.43.410.02.1-1.2-1.21.82.6-1.6-3.2-0.62.52.0-2.2-2.7-2.50.80.6-0.6-0.6-1.11.4
Locomotion velocity, session 30.20.21.3-1.1-0.4-0.4-0.60.40.6-0.50.10.5-0.5-0.5-0.6-0.50.20.1-0.1-0.10.2-0.3
Locomotion distance, session 31.01.12.6-1.61.00.5-0.10.41.4-0.70.90.9-1.0-1.2-1.4-0.91.31.2-1.2-1.2-0.80.9
Stereotopy head waving bouts, day 30.60.75.10.0-0.9-0.1-2.3-0.5-0.8-0.20.2-0.90.41.30.80.7-0.6-0.10.10.11.1-0.4
Stereotopy head waving duration, day 30.60.71.80.9-1.4-0.6-1.3-0.0-1.3-0.4-0.4-0.60.81.00.80.4-0.8-0.50.50.51.1-0.6
Locomotion velocity, session 70.30.31.6-1.30.30.3-0.8-0.11.0-0.00.7-0.2-0.60.1-0.20.20.80.6-0.6-0.6-0.20.1
Locomotion distance, session 70.70.92.4-1.51.10.8-0.9-0.81.10.31.2-0.6-1.10.3-0.10.61.41.0-1.0-1.0-0.60.8
Stereotopy head waving bouts, day 70.40.41.4-0.40.90.80.60.61.00.10.20.10.4-0.8-0.6-0.00.70.7-0.7-0.7-1.20.3
Stereotopy head waving duration, day 70.50.61.9-0.91.21.2-0.10.01.40.50.8-0.4-0.2-0.2-0.10.40.80.8-0.9-0.9-1.00.3
Locomotion velocity, session 80.60.71.90.8-1.0-1.41.00.9-0.5-1.0-1.01.1-0.2-0.7-0.5-1.1-0.8-0.70.70.70.7-0.3
Locomotion distance, session 80.30.51.3-1.10.20.1-0.7-0.10.8-0.60.90.2-1.0-0.1-0.4-0.20.80.9-0.9-0.9-0.10.7
Degree of sensitization distance1.11.14.0-0.40.30.5-0.9-1.70.11.30.4-2.0-0.61.91.91.90.0-0.10.10.10.1-0.2
Degree of sensitization stereotypy0.80.82.9-0.21.31.01.00.71.00.00.50.40.5-1.1-0.9-0.31.11.0-1.0-1.0-1.70.8
Conditioned locomotion0.70.82.70.7-0.20.2-0.7-1.2-0.31.2-0.4-1.40.41.41.61.5-0.7-0.60.50.50.5-0.9
Cocaine response after cond. corrected1.82.06.5-0.22.31.61.6-0.41.50.91.4-0.6-0.5-0.2-0.30.71.61.8-1.8-1.8-2.61.6
Cocaine response after cond. not corrected2.32.57.0-1.02.51.91.4-0.62.01.01.7-0.7-0.8-0.1-0.20.91.92.0-2.0-2.0-2.61.7
Cocaine response before conditioning0.20.33.2-1.80.10.2-0.8-0.30.6-0.30.5-0.2-0.60.30.10.10.30.1-0.0-0.00.30.2
Saline control response0.30.41.1-0.70.1-0.10.4-0.00.70.4-1.1-0.10.3-0.30.50.1-0.9-1.01.01.00.2-1.0
Bone: connectivity density0.61.05.4-0.80.51.5-2.3-1.20.10.80.8-1.20.51.51.11.20.40.2-0.2-0.20.4-0.2
Bone: cortical apparent density1.01.38.1-2.81.30.80.20.12.50.51.00.1-1.4-1.0-0.5-0.01.00.8-0.8-0.8-1.10.2
Bone: cortical area0.81.23.3-0.60.81.3-1.30.10.3-0.81.7-0.00.3-0.0-0.80.01.81.7-1.7-1.7-0.81.5
Bone: cortical porosity0.80.91.71.3-1.1-1.20.90.4-1.2-0.4-1.30.40.20.00.2-0.3-1.3-1.21.21.21.2-0.6
Bone: cortical porosity1.31.42.91.2-1.5-1.70.90.4-1.2-0.3-1.60.30.10.10.4-0.3-1.7-1.61.61.61.5-1.1
Bone: cortical thickness0.91.54.2-1.80.81.2-2.0-0.71.1-0.01.9-1.0-0.70.70.11.01.61.5-1.5-1.5-0.71.0
Bone: cortical thickness0.60.74.2-2.1-0.5-0.3-1.80.20.8-0.90.80.2-1.3-0.2-0.4-0.30.20.2-0.2-0.21.10.0
Bone: cortical tissue density0.91.27.8-2.81.30.80.20.02.50.60.90.1-1.4-1.0-0.40.00.90.7-0.7-0.7-1.00.1
Condit. Reinf. active minus inactive responses0.50.61.50.8-0.7-1.10.30.2-0.5-0.0-1.00.4-0.5-0.20.3-0.3-1.1-1.01.01.01.2-0.8
Condit. Reinf. active-inactive response ratio0.10.10.6-0.0-0.2-0.40.0-0.0-0.10.3-0.20.3-0.7-0.10.1-0.2-0.5-0.50.50.50.8-0.5
Condit. Reinf. active responses0.40.41.10.7-0.7-0.90.0-0.0-0.5-0.1-1.0-0.0-0.10.20.60.1-0.9-0.91.01.01.0-0.7
Condit. Reinf. inactive responses0.10.10.4-0.1-0.3-0.3-0.00.20.2-0.5-0.6-0.10.6-0.10.30.1-0.3-0.30.30.30.1-0.3
Incentive salience index mean0.80.92.01.4-0.9-1.31.00.3-1.0-0.0-1.40.40.0-0.20.4-0.3-1.3-1.31.31.31.1-0.8
Condit. Reinf. lever presses0.71.03.41.8-0.8-1.01.60.6-1.4-0.3-1.50.61.1-0.30.0-0.4-1.0-1.01.01.00.3-0.4
Condit. Reinf. active minus inactive responses1.21.54.9-0.1-0.5-0.70.82.00.3-2.0-0.32.10.4-2.2-2.2-2.10.10.1-0.1-0.1-0.10.4
Condit. Reinf. active-inactive response ratio1.21.24.0-0.4-0.8-1.10.81.70.4-1.6-0.71.80.2-2.0-1.7-1.9-0.2-0.30.40.40.1-0.1
Condit. Reinf. active responses0.70.92.80.1-0.3-0.61.21.50.2-1.5-0.31.60.3-1.7-1.6-1.70.10.1-0.1-0.1-0.30.4
Condit. Reinf. inactive responses0.10.20.4-0.10.60.50.4-0.10.30.10.5-0.1-0.30.1-0.10.10.70.6-0.6-0.6-0.50.6
Condit. Reinf. lever presses0.10.10.3-0.2-0.1-0.2-0.20.20.2-0.50.30.3-0.4-0.2-0.3-0.40.20.2-0.2-0.20.10.3
Condit. Reinf. lever reinforcers received0.81.13.2-0.00.2-0.31.51.50.4-1.5-0.11.60.3-1.8-1.8-1.60.50.5-0.4-0.4-0.80.8
Conditioned reinforcement - actives0.70.73.21.80.10.5-0.30.9-1.0-0.50.51.00.8-0.8-1.4-0.70.50.6-0.6-0.6-0.10.7
Conditioned reinforcement - inactives0.30.32.00.60.10.3-1.4-0.2-0.40.11.0-0.2-0.90.4-0.20.50.30.5-0.5-0.50.60.5
Conditioned locomotion0.30.41.40.5-0.30.1-1.20.8-0.8-0.70.60.50.1-0.3-0.9-0.20.60.6-0.6-0.60.40.5
Patch foraging indifference point 0 sec0.71.23.7-0.81.01.1-0.7-1.90.21.60.5-1.6-0.61.81.91.60.2-0.20.20.2-0.10.0
Patch foraging indifference point AUC0.91.12.6-0.41.61.3-0.1-1.40.61.50.7-1.6-0.91.41.31.60.40.5-0.5-0.5-0.40.5
Delay disc. indifference point, 0s delay1.71.93.8-0.31.31.9-1.1-2.00.41.01.7-1.70.31.81.11.61.21.5-1.5-1.5-1.31.2
Delay disc. indifference point, 16s delay2.52.66.8-1.62.21.70.8-0.02.40.31.60.1-0.4-1.0-1.10.02.12.1-2.1-2.1-2.61.4
Delay disc. indifference point, 2s delay0.50.62.0-0.80.80.80.4-1.41.41.30.4-0.7-0.20.60.91.0-0.00.1-0.1-0.1-0.5-0.3
Delay disc. indifference point, 24s delay1.71.74.2-0.81.11.2-0.30.61.2-0.71.70.5-0.3-0.7-1.3-0.61.62.0-2.0-2.0-1.61.6
Delay disc. indifference point, 4s delay0.50.51.9-0.50.50.40.1-1.40.71.30.4-0.9-0.60.71.11.00.00.2-0.2-0.2-0.4-0.2
Delay disc. indifference point, 8s delay2.22.26.4-1.42.31.91.0-0.42.20.71.5-0.2-0.4-0.4-0.50.31.81.9-1.9-1.9-2.51.4
Indifference point function ln k0.91.34.90.3-1.0-0.90.81.80.1-1.2-0.52.00.8-2.2-1.8-1.8-0.2-0.20.30.3-0.2-0.3
Indifference point function log k0.91.34.90.3-1.0-0.90.81.80.1-1.2-0.52.00.8-2.2-1.8-1.8-0.2-0.20.30.3-0.2-0.3
Patch foraging total patch changes 0 sec0.81.23.4-0.91.21.1-0.6-1.90.61.70.5-1.6-0.81.71.81.70.3-0.10.10.1-0.2-0.0
Patch foraging total patch changes 12 sec2.22.96.0-1.42.21.9-0.6-2.51.11.81.5-2.4-1.62.22.02.31.41.0-1.0-1.0-1.11.1
Patch foraging total patch changes 18 sec1.82.35.3-1.41.81.5-0.6-2.31.42.10.8-2.3-1.62.12.22.30.20.3-0.3-0.3-0.20.1
Patch foraging total patch changes 24 sec0.70.92.1-0.31.31.3-0.1-0.60.20.11.0-0.8-0.10.90.40.71.51.2-1.2-1.2-1.21.3
Patch foraging total patch changes 6 sec0.71.03.7-0.71.91.30.7-1.30.81.10.8-0.9-1.20.70.71.00.80.6-0.6-0.6-0.91.0
Patch foraging time to switch 0 sec0.00.10.20.1-0.00.0-0.2-0.2-0.3-0.40.2-0.00.00.2-0.1-0.00.20.3-0.3-0.3-0.10.4
Patch foraging water rate 0 sec0.10.21.0-0.90.50.30.1-0.01.00.20.6-0.1-0.9-0.2-0.00.10.60.4-0.4-0.4-0.40.2
Patch foraging water rate 12 sec0.81.24.00.7-0.8-0.60.91.9-0.5-1.7-0.21.61.2-1.7-2.0-1.50.30.4-0.4-0.4-0.70.4
Patch foraging water rate 18 sec0.40.61.70.3-1.3-1.10.31.00.0-0.8-0.90.71.0-0.6-0.3-0.6-0.6-0.90.90.90.3-0.9
Patch foraging water rate 24 sec1.31.84.9-1.50.70.41.41.71.4-1.40.50.80.6-1.7-1.8-0.91.61.4-1.4-1.4-2.21.2
Patch foraging water rate 6 sec1.31.96.40.6-1.9-1.60.52.4-0.5-2.5-0.81.91.0-1.9-2.0-2.0-0.2-0.20.20.20.3-0.1
Seeking ratio, delayed vs. immediate footshock0.70.92.4-0.10.60.5-0.01.30.4-1.00.90.7-0.1-0.9-1.6-0.81.11.2-1.2-1.2-0.61.2
Distance traveled before self-admin1.01.03.4-1.20.50.9-1.8-1.10.80.70.9-1.6-0.21.51.61.31.00.4-0.3-0.3-0.30.0
Distance traveled after self-admin0.20.20.9-0.2-0.10.3-0.9-0.3-0.30.10.1-0.90.41.00.90.70.20.00.00.00.1-0.0
Extensor digitorum longus weight0.41.43.50.9-1.9-1.5-0.30.3-1.4-0.6-1.40.00.70.40.3-0.3-1.5-1.61.61.61.6-1.2
Bone: elastic displacement0.91.03.6-0.4-1.9-1.7-1.30.3-0.5-1.0-0.50.4-0.90.10.1-0.5-1.0-0.90.90.91.7-0.9
Bone: elastic work0.70.93.10.0-1.7-1.3-0.91.2-0.8-1.8-0.21.10.1-0.8-1.1-1.2-0.4-0.30.30.31.1-0.2
Bone: endosteal estimation0.20.52.41.5-0.2-0.21.10.9-1.0-0.7-0.60.90.9-0.7-0.8-1.0-0.2-0.0-0.0-0.00.20.3
Bone: endosteal perimeter0.30.61.61.20.90.61.30.7-0.1-0.20.00.90.5-1.0-1.1-0.80.70.6-0.6-0.6-0.80.8
Epididymis fat weight0.40.92.8-0.91.61.40.4-0.61.00.61.0-0.5-0.20.00.00.61.61.0-1.0-1.0-1.71.0
Delta time in closed arm before/after self-admin2.42.36.0-0.8-0.5-0.2-1.4-2.10.31.8-0.5-2.2-0.62.22.51.8-1.8-1.31.31.31.7-1.8
Delta time in open arm before/after self-admin0.70.62.2-0.8-0.0-0.3-0.1-1.00.81.2-0.4-0.8-0.90.61.50.7-0.3-0.90.90.90.2-1.0
Diff in mean of infusions in LGA sessions1.41.64.9-0.9-1.2-1.4-0.10.61.2-0.1-1.70.6-0.3-0.90.1-0.6-1.9-1.71.61.61.6-2.2
Delay discount exponential model param1.21.34.81.5-1.6-1.3-0.70.5-2.2-0.7-1.10.10.50.50.2-0.2-1.2-1.31.31.31.8-0.6
Extinction: sum of active levers before priming0.90.93.00.8-0.0-0.1-0.3-1.3-0.51.7-0.6-1.0-0.41.01.50.9-0.9-0.90.90.90.8-1.2
Active lever presses in extinction session 61.91.85.5-0.3-1.2-1.4-1.5-0.8-0.00.7-1.2-0.4-1.20.71.40.0-1.5-1.91.81.82.3-2.0
Bone: final force0.81.33.1-0.71.21.2-1.2-1.00.30.11.8-1.0-1.30.90.20.91.41.4-1.4-1.4-0.51.5
Bone: final moment0.71.22.8-0.71.11.2-1.2-0.80.2-0.11.7-1.0-0.80.90.20.91.41.5-1.4-1.4-0.61.5
Food consumed during 24 hour testing period0.50.61.80.6-1.3-1.0-0.50.6-1.1-1.3-0.30.70.4-0.2-0.6-0.8-0.5-0.40.40.41.0-0.1
Glucose0.50.82.2-0.10.71.5-1.20.10.1-0.31.1-0.51.10.60.00.51.41.2-1.2-1.2-0.90.9
Heart weight0.60.93.50.1-1.9-1.6-0.40.9-0.4-1.2-1.20.70.8-0.40.1-0.7-0.9-1.00.90.90.8-1.1
Delay discount hyperbolic model param1.11.24.61.5-1.5-1.2-0.60.8-2.1-0.9-1.10.40.50.2-0.2-0.5-1.0-1.11.11.11.6-0.5
Intermittent access intake day 1-15 change0.70.72.10.51.00.71.00.10.1-0.10.60.40.1-0.7-0.80.21.11.1-1.1-1.1-1.41.2
Intermittent access intake escalation0.90.93.10.11.51.01.3-0.00.50.20.70.1-0.1-0.6-0.60.61.31.1-1.1-1.1-1.81.2
Intermittent access intake escalation 20.90.94.10.80.40.02.01.0-0.1-0.9-0.31.10.7-1.5-1.4-0.70.70.4-0.4-0.4-1.30.8
Intermitt. access day 1 inactive lever presses0.90.93.9-0.30.70.7-0.5-1.10.31.10.5-1.7-0.61.91.72.00.30.2-0.2-0.2-0.30.2
Intermitt. access day 15 inactive lever presses0.60.71.60.4-0.6-0.50.7-0.1-0.70.4-1.3-0.50.80.50.80.6-1.2-1.31.31.30.5-0.9
Intermitt. access escalation Index1.51.44.00.4-1.2-1.21.01.6-0.7-2.0-1.01.90.9-1.6-1.6-1.7-0.6-0.40.40.40.40.1
Intermittent access day 1 total infusions0.91.15.6-0.10.71.5-2.4-0.7-0.40.31.7-0.6-0.11.00.20.51.01.3-1.3-1.30.10.9
Intermittent access day 15 total infusions1.21.33.60.11.41.6-0.9-0.70.10.51.9-0.4-0.50.4-0.20.81.71.6-1.6-1.6-1.01.4
Intermittent access terminal intake (last 3 days)0.70.81.80.70.81.3-0.7-0.3-0.60.11.3-0.10.50.2-0.40.41.21.2-1.2-1.2-0.71.2
Intermittent access total infusions0.91.02.80.70.91.5-1.4-0.4-0.50.41.7-0.30.00.5-0.20.51.31.4-1.4-1.4-0.41.1
Intermittent access day 1 locomotion1.41.47.2-1.00.61.0-2.7-1.40.30.72.0-0.8-1.61.30.70.51.11.2-1.2-1.20.50.7
Intermittent access day 15 total locomotion2.12.29.7-1.70.71.0-3.1-1.81.01.12.1-1.4-2.21.71.21.41.01.1-1.1-1.10.60.3
Intermittent access total locomotion1.31.56.9-1.10.61.0-2.6-1.40.30.72.1-0.9-1.51.30.70.91.01.3-1.3-1.30.30.7
Intermittent access standard deviation0.40.41.11.10.30.70.20.1-0.7-0.10.60.10.80.0-0.50.40.90.8-0.8-0.8-0.90.8
Left kidney weight0.41.14.4-0.8-0.8-0.80.40.41.00.7-1.40.20.5-0.60.5-0.2-1.4-1.51.51.50.7-2.1
Right kidney weight0.10.41.8-1.40.2-0.1-0.3-0.71.21.00.1-0.5-1.00.10.60.5-0.2-0.10.10.10.2-0.8
Cocaine induced anxiety0.60.72.60.71.20.81.6-1.1-0.41.5-0.1-1.0-0.20.70.91.30.1-0.20.20.2-0.70.3
Post-drug Anxiety0.40.52.71.30.70.61.6-0.3-1.00.9-0.3-0.41.00.30.20.50.0-0.00.00.0-0.80.3
Baseline Anxiety0.30.30.9-0.5-0.3-0.2-0.30.90.8-0.5-0.10.80.5-1.0-0.7-0.7-0.10.2-0.2-0.2-0.2-0.3
Tail length0.41.23.6-1.41.41.4-0.80.31.80.11.40.1-0.5-0.7-0.7-0.21.91.3-1.3-1.3-1.00.7
Length with tail0.20.62.7-0.81.30.70.6-0.51.61.30.5-0.5-1.3-0.30.30.51.00.2-0.1-0.1-0.7-0.1
Length without tail0.20.41.40.30.2-0.41.0-0.70.21.2-0.6-0.3-0.90.10.60.4-0.6-0.80.80.80.3-0.7
Times rat made contact with spout1.61.94.31.4-2.1-1.70.41.2-1.6-1.3-1.71.11.5-0.6-0.6-1.1-1.6-1.51.51.51.3-1.0
Lifetime Intake1.31.43.90.71.01.7-1.8-0.6-0.60.22.0-0.50.10.8-0.20.61.51.7-1.7-1.7-0.51.5
Liver weight, left1.93.011.51.80.71.80.21.3-1.3-1.60.91.23.4-1.1-2.2-1.21.91.9-1.9-1.9-2.02.0
Liver weight, right1.01.63.90.9-0.9-0.91.81.7-0.5-1.3-1.51.71.7-2.0-1.6-1.9-0.4-0.60.60.6-0.2-0.4
Locomotor activity0.10.20.7-0.7-0.7-0.8-0.30.40.1-0.90.00.5-0.5-0.5-0.6-0.5-0.10.1-0.1-0.10.30.1
Locomotor testing distance0.20.30.9-0.6-0.1-0.20.00.40.3-0.90.40.7-0.5-0.7-0.7-0.70.50.7-0.7-0.7-0.50.7
Locomotor testing rearing0.20.31.5-1.2-0.3-0.3-1.1-0.40.5-0.10.5-0.2-1.20.30.30.20.10.1-0.1-0.10.30.1
Locomotion in novel chamber1.21.53.6-1.61.31.2-1.6-0.41.90.11.8-0.2-1.60.1-0.30.41.71.4-1.4-1.4-0.60.9
Locomotion in novel chamber post-restriction0.20.22.20.0-0.6-0.2-1.5-0.0-0.4-0.60.4-0.1-0.30.4-0.2-0.30.1-0.00.00.00.9-0.0
Fecal boli incidents, locomotor time 10.80.92.5-0.90.1-0.50.5-1.01.21.6-0.7-0.2-1.0-0.11.10.2-0.9-1.21.21.20.5-1.5
Change in fecal boli incidents, locomotor task0.30.31.2-1.0-0.10.0-1.10.40.7-0.40.9-0.2-0.70.0-0.5-0.2-0.10.7-0.7-0.70.30.2
Time >=10cm from walls, locomotor time 10.00.00.20.0-0.1-0.10.5-0.1-0.2-0.2-0.1-0.00.30.20.1-0.1-0.1-0.00.00.0-0.00.1
Bouts of movement, locomotor time 10.70.73.9-1.51.0-0.11.60.42.00.5-0.40.3-1.2-1.2-0.3-0.1-0.1-0.00.00.0-0.9-0.3
Total resting periods, locomotor time 10.30.41.9-0.80.7-0.11.30.21.40.7-0.50.0-0.7-0.70.10.3-0.3-0.20.20.2-0.6-0.4
Rest time, locomotor task time 10.10.10.60.4-0.3-0.2-0.3-0.5-0.30.1-0.3-0.30.10.40.50.1-0.8-0.30.30.30.5-0.3
Distance moved, locomotor task time 10.20.20.7-0.20.0-0.00.50.5-0.0-0.70.20.50.1-0.6-0.8-0.20.70.5-0.5-0.5-0.50.5
Vertical activity count, locomotor time 10.20.20.7-0.60.50.20.80.20.90.10.20.4-0.4-0.7-0.6-0.50.40.3-0.3-0.3-0.40.0
Time >=10cm from walls, locomotor time 20.20.20.60.7-0.4-0.1-0.1-0.1-0.30.2-0.4-0.30.80.50.50.0-0.6-0.40.40.40.2-0.5
Bouts of movement, locomotor time 20.20.20.9-0.1-0.5-0.70.60.30.1-0.5-0.90.30.4-0.40.1-0.5-0.2-0.20.20.2-0.4-0.3
Total resting periods, locomotor time 20.10.10.80.0-0.3-0.60.70.10.2-0.4-0.90.30.3-0.30.2-0.4-0.2-0.10.10.1-0.4-0.2
Rest time, locomotor task time 20.60.72.3-0.70.0-0.3-0.2-1.30.81.2-0.4-1.0-0.90.81.50.8-1.0-0.50.50.50.5-0.9
Distance moved, locomotor task time 20.91.02.30.9-0.00.5-0.01.0-1.1-1.40.50.61.5-0.5-1.5-0.51.51.1-1.1-1.1-1.11.3
Vertical activity count, locomotor time 20.70.82.80.10.30.30.10.9-0.0-1.00.91.00.0-1.0-1.7-1.11.40.9-0.9-0.9-0.71.1
Light reinforcement 10.20.41.61.0-0.9-0.80.30.2-1.3-0.8-0.7-0.20.80.30.20.1-0.6-0.40.50.50.10.1
Light reinforcement 20.91.12.71.1-1.4-1.50.20.4-0.9-0.2-1.5-0.10.40.20.60.0-1.4-1.61.71.71.1-1.2
Bone: marrow area0.20.52.21.5-0.1-0.11.20.9-0.9-0.6-0.50.90.9-0.7-0.8-1.0-0.10.0-0.1-0.10.10.3
Bone: maximum diameter0.40.71.71.30.70.80.70.6-0.4-0.60.50.51.1-0.6-0.9-0.41.21.0-1.0-1.0-1.11.2
Bone: maximum force0.61.02.6-0.51.01.3-1.2-0.40.1-0.11.6-0.6-0.40.5-0.30.61.51.5-1.5-1.5-0.71.4
Bone: maximum moment0.61.12.5-0.41.01.4-1.2-0.30.0-0.31.6-0.60.10.5-0.30.51.61.5-1.5-1.5-0.81.5
Mean time between licks in bursts0.91.34.8-0.70.4-0.41.21.61.3-1.10.21.4-0.8-2.2-2.0-1.50.80.6-0.6-0.6-0.70.6
Mean num. licks in bursts0.91.12.81.0-1.7-1.3-0.00.3-1.2-0.5-1.30.11.00.40.4-0.3-1.5-1.31.31.31.1-1.1
Cd content in liver0.20.20.70.1-0.10.0-0.5-0.4-0.7-0.50.5-0.3-0.30.80.20.10.20.3-0.3-0.30.30.7
Co content in liver0.20.30.9-0.2-0.30.3-1.00.1-0.4-0.60.7-0.30.60.3-0.30.00.60.7-0.8-0.8-0.20.5
Cu content in liver1.82.16.61.2-0.2-0.82.32.2-0.2-1.8-0.72.30.9-2.6-2.3-2.10.20.4-0.4-0.4-1.00.8
Fe content in liver0.81.02.11.4-0.7-1.11.41.1-1.3-1.2-1.01.40.4-1.1-1.2-1.5-0.4-0.50.50.50.40.2
K content in liver3.93.87.12.5-2.6-2.21.01.9-1.7-0.9-2.71.62.3-1.3-0.6-1.6-2.4-2.22.22.21.6-2.2
Mg content in liver0.70.72.81.7-1.2-0.90.20.6-1.5-0.6-0.90.41.2-0.1-0.2-0.4-0.9-0.70.60.60.6-0.4
Mn content in liver0.20.31.10.6-0.5-0.1-0.70.4-0.9-1.00.30.50.6-0.1-0.5-0.5-0.10.3-0.3-0.30.30.5
Na content in liver1.11.25.82.4-0.5-0.21.11.3-1.6-0.6-1.01.02.2-0.9-1.0-1.0-0.6-0.40.40.40.1-0.1
Rb content in liver0.60.81.80.80.61.3-0.9-0.7-0.70.30.7-1.31.11.20.51.20.70.8-0.9-0.9-0.70.7
Se content in liver0.60.81.70.90.90.41.30.70.1-0.40.41.00.1-1.1-1.1-0.81.10.9-0.9-0.9-1.31.1
Sr content in liver0.20.20.8-0.1-0.10.6-0.80.3-0.3-0.60.50.10.9-0.1-0.6-0.20.40.5-0.5-0.5-0.00.4
Zn content in liver1.41.53.41.8-1.2-1.41.81.5-1.2-1.2-1.31.61.0-1.4-1.2-1.6-0.8-0.70.70.70.2-0.2
Bone: minimum diameter1.12.14.60.31.61.21.21.00.7-0.61.41.0-0.1-1.4-1.9-0.92.12.0-2.0-2.0-1.91.9
Time in familiar zone, hab. session 12.22.14.50.9-1.7-2.00.80.9-0.8-0.5-2.10.90.2-1.0-0.2-1.0-2.0-2.02.02.01.9-1.7
Time in novel zone, hab. session 12.32.35.2-1.21.61.9-1.4-1.40.90.82.3-1.5-0.81.50.71.41.81.8-1.8-1.8-1.51.5
Total zone transitions, hab. session 12.43.36.91.2-2.2-2.51.92.5-1.2-2.4-1.72.50.9-2.5-2.3-2.6-0.8-1.11.11.10.6-0.5
Total locomotion distance, hab. session 12.53.57.01.5-2.0-2.42.22.6-1.2-2.1-2.02.60.9-2.6-2.1-2.6-1.1-1.31.31.30.8-0.7
Locomotion velocity, hab. session 12.33.26.81.6-1.7-2.22.42.5-1.1-2.0-2.02.51.2-2.6-2.1-2.5-1.0-1.21.21.20.5-0.5
Time in familiar zone, hab. session 20.40.41.5-0.3-0.3-0.30.41.10.2-1.0-0.50.90.5-1.2-1.0-1.0-0.3-0.10.10.10.0-0.0
Time in novel zone, hab. session 20.50.52.00.4-0.20.1-1.1-0.9-0.80.20.8-0.8-0.41.40.80.90.40.4-0.4-0.40.10.5
Total zone transitions, hab. session 21.92.47.00.9-1.0-1.31.92.2-1.2-2.4-0.72.40.9-2.2-2.6-2.50.20.1-0.1-0.1-0.20.8
Total locomotion distance, hab. session 22.22.97.21.2-1.6-2.12.12.3-1.1-2.3-1.42.60.4-2.5-2.4-2.7-0.5-0.60.60.60.40.1
Locomotion velocity, hab. session 21.82.46.11.2-1.3-1.82.22.1-0.9-2.0-1.32.50.5-2.4-2.2-2.5-0.4-0.60.60.60.30.1
Novel to familiar place preference ratio0.30.31.30.11.10.80.6-0.70.30.80.4-0.5-0.50.50.50.60.40.5-0.5-0.5-0.60.6
Novelty place preference0.30.31.2-0.01.10.60.8-0.60.50.80.1-0.4-0.60.30.50.60.20.2-0.2-0.2-0.50.4
Time in novel zone, NPP test0.30.31.6-0.21.30.80.8-0.60.70.80.3-0.3-0.70.20.40.50.40.4-0.4-0.4-0.70.5
Total zone transitions, NPP test1.31.84.61.0-0.8-1.22.11.8-1.0-2.0-0.92.00.7-2.0-2.1-2.1-0.2-0.10.10.1-0.20.6
Total locomotion distance, NPP test3.44.611.11.8-1.5-2.33.23.1-1.3-2.9-2.03.31.0-3.2-2.9-3.3-0.7-0.60.60.60.00.4
Locomotion velocity, NPP test2.84.09.01.6-1.6-2.43.02.7-1.3-2.6-2.12.90.9-2.9-2.4-3.0-1.0-0.90.90.90.4-0.0
Intraocular pressure1.31.84.2-1.51.21.6-2.0-1.60.60.42.0-1.4-1.01.50.61.31.31.5-1.5-1.5-0.51.3
Delta distance traveled before/after self-admin0.10.10.4-0.3-0.3-0.60.50.1-0.3-0.2-0.50.2-0.2-0.10.0-0.0-0.7-0.30.30.30.3-0.2
Delta ambulatory time before/after self-admin0.20.31.41.0-0.1-0.10.50.2-1.2-0.60.10.50.3-0.1-0.6-0.3-0.20.4-0.4-0.40.00.7
Parametrial fat weight0.61.23.61.50.10.40.81.6-0.3-1.10.11.21.5-1.5-1.9-1.20.70.8-0.8-0.8-1.00.7
Pavlov. Cond. lever latency0.20.31.10.10.30.10.30.3-0.3-0.80.40.3-0.4-0.4-0.9-0.40.60.7-0.7-0.7-0.31.1
Pavlov. Cond. magazine entry latency0.50.72.1-1.30.80.9-0.6-1.11.21.50.4-0.9-0.30.81.11.00.20.0-0.0-0.0-0.2-0.6
Pavlov. Cond. change in total contacts0.10.10.7-0.70.40.4-0.0-0.50.60.80.3-0.3-0.30.30.40.3-0.10.0-0.0-0.00.0-0.3
Pavlov. Cond. index score0.20.21.3-0.90.30.3-0.0-0.21.20.9-0.0-0.0-0.0-0.10.50.2-0.0-0.20.30.3-0.2-0.8
Pavlov. Cond. latency score0.20.20.9-0.60.10.1-0.1-0.30.90.9-0.2-0.10.00.10.70.3-0.3-0.40.40.4-0.1-0.9
Pavlov. Cond. lever contacts0.20.20.90.1-0.3-0.20.50.00.30.6-0.60.10.5-0.10.50.1-0.6-0.70.70.70.0-1.0
Pavlov. Cond. magazine entry number0.50.73.11.8-0.7-0.70.60.7-1.7-1.4-0.30.70.4-0.3-0.9-0.8-0.10.1-0.1-0.10.20.9
Pavlov. Cond. intertrial magazine entries0.70.84.4-0.2-0.2-1.41.3-0.10.70.4-0.90.3-2.1-0.60.2-0.3-1.0-0.90.90.90.8-0.7
Pavlov. Cond. lever-magazine prob. diff.0.10.10.8-0.60.30.40.1-0.00.90.70.10.20.1-0.30.10.00.2-0.00.00.0-0.4-0.5
Pavlov. Cond. response bias0.20.31.3-0.70.70.80.1-0.31.01.20.3-0.30.20.00.40.60.30.1-0.1-0.1-0.7-0.5
Pavlov. Cond. lever latency0.40.61.60.4-1.3-1.0-0.10.5-1.1-0.5-0.90.50.6-0.3-0.2-0.5-0.7-0.90.90.91.0-0.8
Pavlov. Cond. magazine entry latency1.11.34.1-1.11.91.60.1-0.82.01.30.9-1.0-0.30.30.61.11.21.0-1.0-1.0-1.70.4
Pavlov. Cond. change in total contacts0.70.93.4-1.01.71.10.70.01.80.40.9-0.1-0.7-0.6-0.40.11.01.0-1.0-1.0-1.30.8
Pavlov. Cond. index score0.81.04.0-1.11.81.30.5-0.62.01.20.9-0.7-0.80.00.30.70.90.9-0.9-0.9-1.30.5
Pavlov. Cond. latency score0.81.04.6-1.01.81.20.8-0.42.11.20.6-0.5-0.6-0.20.20.60.70.7-0.7-0.7-1.40.3
Pavlov. Cond. lever contacts0.30.41.3-0.51.10.90.2-0.41.00.50.6-0.4-0.40.10.20.40.40.7-0.6-0.6-0.90.6
Pavlov. Cond. magazine entry number1.92.46.11.8-2.3-2.10.81.3-2.5-1.6-1.71.51.2-0.7-0.7-1.4-1.6-1.51.51.51.6-0.7
Pavlov. Cond. intertrial magazine entries0.10.10.8-0.0-0.4-0.40.1-0.4-0.9-0.10.1-0.3-0.30.60.30.3-0.30.0-0.1-0.10.40.2
Pavlov. Cond. lever-magazine prob. diff.0.91.14.5-1.21.91.40.4-0.72.11.30.9-0.7-1.00.00.30.80.80.9-0.8-0.8-1.30.4
Pavlov. Cond. response bias0.81.13.0-0.71.71.50.0-0.51.30.51.3-0.5-0.50.1-0.10.51.31.4-1.4-1.4-1.51.2
Time in closed arm before self-admin1.01.13.1-0.81.41.00.90.61.1-0.21.1-0.0-0.6-0.8-1.00.21.61.3-1.2-1.2-1.81.4
Time in closed arm after self-admin0.40.41.1-0.70.40.20.3-0.71.01.0-0.1-1.1-0.40.50.80.8-0.5-0.40.40.40.0-0.6
Time in open arm before self-admin0.60.62.31.0-1.1-0.5-1.40.3-1.1-0.4-0.40.40.80.40.2-0.5-1.0-0.60.60.61.5-0.7
Time in open arm after self-admin0.60.61.50.1-0.7-0.6-0.9-0.6-0.10.8-0.5-0.3-0.40.61.20.2-0.7-1.11.11.11.2-1.2
Bone: periosteal estimation0.30.51.20.70.20.40.10.9-0.4-0.90.50.70.8-0.7-1.1-0.70.90.9-0.9-0.9-0.40.9
Bone: periosteal perimeter0.50.92.10.31.51.40.50.20.5-0.20.80.20.4-0.5-0.8-0.11.41.3-1.3-1.3-1.21.3
Bone: post-yield work0.50.72.60.90.41.4-1.2-0.2-0.70.10.8-0.71.60.80.10.60.90.9-0.9-0.9-0.50.6
Progressive ratio test 1 active lever presses0.50.54.5-0.20.30.9-2.1-0.50.20.31.0-0.3-0.00.60.30.50.50.6-0.6-0.60.50.1
Progressive ratio test 1 breakpoint0.50.55.8-0.00.10.9-2.4-0.5-0.00.30.9-0.30.30.70.30.60.40.5-0.5-0.50.7-0.0
Progressive ratio test 1 inactive lever presses0.80.94.20.10.31.2-2.0-0.7-0.3-0.21.2-1.00.71.20.41.10.91.0-1.0-1.0-0.30.8
Progressive ratio test 2 active lever presses0.30.31.81.1-0.20.2-1.30.0-1.0-0.20.7-0.10.00.4-0.20.40.20.4-0.4-0.40.60.4
Progressive ratio test 2 breakpoint0.30.42.11.1-0.10.4-1.40.0-0.9-0.10.80.0-0.10.3-0.30.40.30.5-0.5-0.50.60.5
Progressive ratio test 2 inactive lever presses0.10.10.70.60.10.2-0.8-0.2-0.30.40.50.0-0.40.20.00.3-0.10.2-0.2-0.20.50.0
Incentive Sensitization - Responses0.30.31.31.0-0.20.1-0.8-0.2-1.2-0.20.5-0.2-0.20.5-0.10.60.20.3-0.3-0.30.50.5
Incentive Sensitization - Breakpoint0.20.21.10.8-0.10.2-0.9-0.2-1.0-0.10.6-0.3-0.30.6-0.10.70.30.3-0.3-0.30.40.5
Sum of active levers in priming session hrs 5-61.21.12.8-0.2-0.5-1.21.21.11.30.2-1.51.1-0.2-1.7-0.4-1.1-1.0-1.21.11.10.4-1.6
Progressive ratio3.43.99.0-2.02.52.6-1.9-1.72.11.23.0-1.4-1.61.20.50.92.42.4-2.4-2.4-1.61.7
Food seeking constrained by brief footshock0.81.03.0-0.6-0.8-1.21.10.81.20.5-1.30.3-0.1-1.10.2-0.3-1.4-1.31.21.20.5-1.7
Seeking ratio, punishment vs. effort3.03.69.11.0-2.0-2.62.52.2-0.5-0.7-3.01.51.1-2.0-0.6-1.0-2.4-2.32.32.31.0-2.2
Retroperitoneal fat weight0.10.31.1-0.2-0.2-0.20.90.70.1-0.3-0.80.71.0-1.0-0.5-0.6-0.2-0.30.30.3-0.2-0.5
Reaction time number correct1.21.811.92.8-1.5-0.2-0.31.4-2.4-1.3-0.80.73.4-0.2-0.8-0.6-0.2-0.40.50.50.1-0.1
Reaction time mean minus median2.63.510.0-1.03.22.70.3-1.62.01.52.3-1.3-1.10.70.41.42.32.2-2.2-2.2-2.21.9
Reaction time mean minus median AUC3.24.210.2-0.43.23.10.1-1.51.21.32.6-1.5-0.61.00.21.62.72.7-2.6-2.6-2.62.5
Reaction time num false alarms1.01.43.8-0.9-1.4-1.4-0.4-0.10.10.3-1.50.2-0.2-0.00.9-0.1-1.8-1.71.71.71.5-2.0
Reaction time num false alarms AUC1.01.44.1-1.2-1.0-1.0-0.6-0.60.50.8-1.2-0.4-0.40.51.50.4-1.7-1.61.61.61.4-2.0
Reaction time trials correct on left1.21.811.92.8-1.5-0.2-0.31.4-2.4-1.3-0.80.73.4-0.2-0.8-0.6-0.2-0.40.50.50.1-0.1
Reaction time trials on left1.11.610.92.6-1.4-0.1-0.41.3-2.3-1.1-0.80.53.3-0.1-0.6-0.4-0.3-0.50.50.50.1-0.2
Reaction time mean5.98.223.1-4.73.42.2-1.3-3.54.83.82.3-3.2-4.82.22.93.01.31.0-1.0-1.0-0.5-0.2
Reaction time mean AUC5.06.720.1-4.23.11.9-1.0-3.24.53.61.9-2.8-4.41.82.62.71.00.7-0.7-0.7-0.4-0.4
Median of all reaction times6.18.328.6-5.32.91.5-1.4-3.45.13.91.9-3.1-5.32.03.02.90.70.4-0.4-0.40.2-1.0
Reaction time omissions2.12.87.6-1.72.01.5-0.3-2.52.02.81.1-2.5-1.92.02.22.40.50.5-0.5-0.5-0.5-0.2
Reaction time false alarm rate1.11.54.9-2.2-0.4-0.9-0.7-1.11.31.1-0.6-0.6-2.00.61.60.6-1.4-1.21.11.11.4-1.6
Reaction time premature initiation rate1.01.42.8-1.6-1.2-1.6-0.31.61.2-1.4-0.51.6-1.1-1.6-1.1-1.7-0.5-0.60.60.61.1-0.8
Reaction time premature initiations1.11.54.30.1-1.9-1.5-0.52.1-0.3-1.9-0.91.61.0-1.4-1.2-1.7-0.6-0.70.80.81.0-0.9
Std. dev. reaction times3.54.912.0-2.83.42.7-0.6-2.53.52.52.4-2.1-2.71.41.42.11.91.8-1.7-1.7-1.51.0
Reaction time trials completed1.11.610.92.6-1.4-0.1-0.41.3-2.3-1.1-0.80.53.3-0.1-0.6-0.4-0.3-0.50.50.50.1-0.2
Reaction time trials AUC1.21.710.32.6-1.6-0.4-0.21.4-2.3-1.2-1.00.73.2-0.3-0.7-0.6-0.5-0.70.70.70.3-0.4
Run reversals in cocaine runway, females0.40.41.0-1.00.70.7-0.5-0.50.4-0.10.7-0.5-0.20.50.30.40.80.8-0.9-0.9-0.70.7
Run reversals in cocaine runway, males0.40.41.20.2-0.2-0.80.80.20.50.5-0.80.1-0.8-0.20.3-0.0-1.1-0.90.90.90.7-0.9
Latency to leave start box in cocaine runway1.51.64.70.51.62.2-0.8-0.3-0.00.41.6-0.71.10.6-0.10.71.71.8-1.7-1.7-1.61.6
Latency to leave start box in cocaine runway, F0.40.41.00.90.71.0-0.3-0.6-0.50.90.4-0.90.50.90.60.60.20.4-0.4-0.4-0.40.4
Latency to leave start box in cocaine runway, M2.92.86.7-1.72.12.6-1.5-0.31.70.32.1-1.00.40.50.01.22.42.1-2.1-2.1-2.11.6
Std. dev. time between licks in bursts0.60.72.0-1.1-0.2-0.4-0.7-0.71.11.2-0.4-0.7-1.20.20.90.6-0.7-0.90.90.91.0-1.4
Total sessions with >9 infusions0.70.72.80.70.31.2-1.7-0.3-1.0-0.41.3-0.30.60.8-0.20.30.91.0-1.0-1.00.01.2
Short access day 1 total inactive lever presses1.82.05.7-0.90.81.2-2.4-1.90.71.61.8-1.9-1.62.01.62.00.90.8-0.8-0.80.10.2
Short access day 10 total inactive lever presses2.02.35.50.5-2.1-1.90.81.3-0.9-0.8-2.30.41.4-0.40.20.0-2.1-2.12.12.11.3-1.8
Short access day 1 total infusions0.91.02.60.40.81.6-1.5-0.4-0.40.11.3-0.71.00.7-0.10.71.31.4-1.4-1.4-0.81.0
Short access day 10 total infusions1.61.75.0-0.61.31.9-2.0-0.90.20.22.2-0.8-0.40.9-0.10.51.61.9-1.9-1.9-0.61.5
Short access total infusions0.80.92.60.60.71.5-1.6-0.7-0.70.11.4-0.40.60.7-0.20.41.01.3-1.3-1.3-0.31.1
Short access day 1 locomotion1.21.33.90.21.31.40.20.50.4-0.21.20.40.5-0.8-1.1-0.22.01.5-1.5-1.5-1.71.4
Short access day 10 total locomotion0.80.92.8-1.60.80.6-0.7-0.91.00.71.4-0.6-1.70.70.60.51.20.9-0.9-0.9-0.50.5
Short access total locomotion0.10.20.5-0.10.40.4-0.10.1-0.00.00.60.2-0.1-0.1-0.3-0.30.70.6-0.6-0.6-0.40.5
One hour access (0.3 mA shock)0.70.82.2-0.11.01.1-1.4-0.7-0.10.71.5-0.7-1.20.90.30.91.20.9-0.9-0.90.10.8
Compulsive drug intake0.20.20.6-0.1-0.2-0.50.80.20.30.1-0.7-0.5-0.10.40.70.5-0.6-0.50.50.50.1-0.4
One hour access (shock baseline)0.91.02.60.11.41.6-1.0-0.7-0.10.71.6-0.4-0.60.3-0.30.51.61.3-1.3-1.3-0.61.2
Social response proportion2.83.08.2-0.2-1.8-1.9-0.8-0.70.11.1-1.6-0.5-0.90.51.40.5-2.6-2.52.62.62.6-2.9
Social responses1.41.85.30.9-2.2-1.7-1.30.0-1.4-0.6-1.30.40.50.20.4-0.5-2.0-1.51.51.52.3-1.6
Social time0.20.30.9-0.90.30.2-0.6-0.80.50.30.4-0.9-0.70.70.80.70.20.1-0.1-0.1-0.20.1
Soleus weight0.31.05.22.1-0.8-0.0-0.10.8-2.3-1.2-0.40.62.10.2-0.6-0.60.1-0.10.20.20.30.4
Bone: stiffness0.71.12.8-0.41.21.20.20.40.5-0.41.20.20.1-0.6-1.0-0.21.71.5-1.5-1.5-1.41.5
Tibialis anterior weight0.20.61.5-0.4-0.4-0.70.2-0.50.40.5-0.9-0.4-0.70.40.90.4-1.0-1.21.21.20.7-1.0
Time to tail flick, vehicle, before self-admin0.70.72.1-1.5-0.7-0.9-0.60.10.6-0.3-1.10.1-0.3-0.00.80.3-1.0-1.01.01.01.0-1.1
Time to tail flick, vehicle, after self-admin0.60.72.4-1.20.81.00.1-0.60.7-0.40.5-0.40.90.10.10.71.10.9-0.9-0.9-1.50.8
Time to tail flick, test, before self-admin2.92.87.81.3-0.8-1.02.22.8-0.5-2.3-1.42.32.0-2.8-2.7-2.3-0.3-0.30.30.3-0.60.2
Time to tail flick, test, after self-admin2.22.27.00.1-0.1-0.61.72.30.3-2.3-0.02.30.3-2.6-2.6-2.20.90.7-0.6-0.6-0.91.1
Delta time to tail flick, vehicle, before/after SA1.11.12.90.51.31.50.2-1.0-0.00.61.3-0.60.40.4-0.20.41.51.3-1.3-1.3-1.71.3
Delta time to tail flick, test, before/after SA0.50.41.5-0.50.80.60.2-0.10.5-0.11.00.1-0.6-0.1-0.2-0.11.20.9-0.9-0.9-0.81.0
Tibia length0.61.64.21.01.91.41.6-0.7-0.00.81.5-0.4-0.30.1-0.40.51.81.5-1.5-1.5-2.12.0
Ambulatory time before self-admin1.01.02.5-1.30.61.0-1.6-0.91.10.61.0-1.5-0.31.41.41.21.30.5-0.5-0.5-0.60.2
Ambulatory time after self-admin0.30.31.3-0.4-0.10.2-1.2-0.50.00.30.3-0.9-0.11.01.00.60.10.0-0.0-0.00.3-0.2
Bone: tissue strength0.50.41.10.7-0.8-1.00.90.6-0.6-0.5-1.10.50.3-0.4-0.1-0.5-0.8-0.80.80.80.3-0.5
Total heroin consumption0.40.51.60.4-0.7-0.8-0.1-0.40.10.4-0.9-0.3-0.10.20.70.1-1.3-0.90.90.90.9-1.1
Bone: trabecular number1.52.311.6-1.70.61.7-3.4-1.90.41.31.5-2.0-0.22.41.82.00.50.4-0.4-0.40.6-0.2
Bone: trabecular spacing1.31.64.81.60.71.00.50.6-1.3-1.40.80.51.6-0.2-1.3-0.61.41.7-1.7-1.7-1.42.2
Bone: trabecular thickness1.82.15.1-0.2-2.0-1.90.11.20.2-0.6-1.91.00.5-1.0-0.0-1.0-1.9-2.02.02.01.8-2.3
Bone: trabecular tissue density2.12.96.21.0-1.7-2.12.22.4-0.5-1.5-1.92.30.8-2.5-1.8-2.3-1.6-1.41.41.40.6-1.0
Water consumed over 24 hours1.41.73.90.7-2.0-1.70.21.5-1.0-1.6-1.31.40.9-1.2-1.1-1.5-1.3-1.31.31.31.3-0.9
Number of responses in last shaping day1.21.22.40.8-1.5-1.5-0.10.4-0.7-0.5-1.21.40.3-0.9-0.4-1.3-1.3-1.31.31.31.5-1.3