Hub : Genes

Mea1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain alternative TSS XM_006244567.4 0.04 0.03 1.6e-03 0.04 0.02 0.01 0.03 2.3e-04 2.2e-03 1.9e-02 8.7e-04
2 Brain alternative TSS XM_008766880.2 0.09 0.06 1.5e-07 0.08 0.08 0.06 0.08 6.0e-08 1.1e-07 2.6e-06 1.4e-07
3 BLA alternative TSS XM_008766880.2 0.06 0.05 5.5e-03 0.04 0.03 -0 0.04 2.0e-03 1.0e-02 4.1e-01 4.6e-03
4 NAcc alternative TSS XM_008766880.2 0.03 0.02 8.2e-04 0.03 0.03 0.02 0.03 3.3e-04 4.2e-04 7.3e-04 3.2e-04
5 pVTA alternative TSS XM_008766880.2 0.07 0.05 2.1e-03 0.06 0.04 0.01 0.03 1.9e-03 5.6e-03 1.0e-01 1.9e-02
6 Liver alternative TSS XM_008766880.2 0.04 0.03 3.5e-05 0.04 0.03 0.03 0.04 6.0e-05 9.9e-05 5.0e-04 5.6e-05
7 PL alternative TSS XM_008766880.2 0.05 0.03 4.6e-07 0.05 0.06 0.03 0.05 1.9e-06 5.3e-07 4.9e-04 2.3e-06
8 Brain gene expression Mea1 0.03 0.02 6.9e-03 0.01 0 0 0 4.8e-02 3.4e-01 1.1e-01 2.4e-01
9 Adipose alternative TSS XM_008766880.2 0.02 0.02 2.4e-03 0.01 0.01 0.01 0.01 4.6e-02 1.3e-02 4.4e-02 2.8e-02
10 BLA gene expression Mea1 0.14 0.16 9.0e-03 0.04 0.01 0.04 0.02 2.1e-03 5.5e-02 5.0e-03 2.2e-02
11 LHb intron excision ratio chr9_14301586_14301993 0.17 0.11 7.3e-03 0.09 0.06 0.04 0.06 3.7e-03 1.5e-02 3.2e-02 1.8e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.40.72.10.6-0.6-0.60.7-0.70.60.2-1.4-0.21.3-1.0
Area under the delay curve7.47.810.43.2-3.2-3.03.0-3.03.03.2-1.13.2-2.01.9
BMI with tail3.110.114.6-3.83.83.8-3.63.7-3.6-3.33.2-2.7-0.0-0.3
BMI without tail9.419.427.7-5.25.25.3-5.05.1-5.1-4.83.9-4.10.8-0.7
Body weight2.39.713.4-3.73.73.7-3.53.6-3.6-3.52.1-3.11.3-0.7
Weight adjusted by age0.20.20.4-0.40.40.5-0.60.6-0.6-0.40.6-0.30.20.1
Bone surface1.01.83.81.4-1.4-1.51.6-1.61.51.1-1.90.71.0-0.5
Bone volume0.40.81.90.9-0.9-0.91.0-1.00.90.6-1.40.30.9-0.5
Breakpoint value in progressive ratio session0.10.10.50.1-0.1-0.10.10.00.20.30.50.4-0.10.7
Number of licking bursts4.04.77.2-2.12.12.1-2.22.1-2.2-2.50.3-2.72.2-2.4
Context. condit. distance diff. score0.20.31.0-0.40.40.4-0.40.3-0.4-0.5-0.5-0.61.0-0.0
Locomotion velocity, session 10.70.82.4-0.70.70.7-0.70.7-0.6-0.31.60.2-1.21.4
Locomotion distance, session 11.72.23.1-1.81.81.6-1.71.7-1.7-1.61.1-1.40.60.1
Locomotion velocity, session 24.14.86.8-2.52.52.6-2.62.6-2.6-2.12.4-1.6-0.00.9
Locomotion distance, session 21.01.42.2-1.51.51.3-1.41.3-1.4-1.21.4-0.9-0.10.4
Locomotion velocity, session 30.60.71.8-0.60.60.7-0.70.7-0.6-0.31.30.1-1.21.4
Locomotion distance, session 31.01.11.90.9-0.9-1.01.0-1.01.11.20.21.3-1.31.4
Stereotopy head waving bouts, day 31.01.21.7-1.31.31.2-1.31.2-1.3-1.30.6-1.20.2-0.6
Stereotopy head waving duration, day 31.51.92.7-1.61.61.6-1.61.6-1.6-1.41.3-1.1-0.4-0.1
Locomotion velocity, session 70.50.51.9-0.40.40.3-0.30.4-0.20.01.30.4-1.21.4
Locomotion distance, session 70.30.41.4-0.30.30.1-0.10.1-0.10.11.10.4-1.21.2
Stereotopy head waving bouts, day 70.20.20.5-0.50.50.5-0.50.4-0.5-0.6-0.1-0.60.7-0.4
Stereotopy head waving duration, day 70.20.31.00.2-0.2-0.10.1-0.10.0-0.1-1.0-0.41.0-0.9
Locomotion velocity, session 80.40.50.9-0.70.70.8-0.90.9-0.9-0.70.5-0.60.30.5
Locomotion distance, session 80.81.11.8-1.31.31.1-1.11.1-1.2-1.20.5-1.10.70.2
Degree of sensitization distance1.31.31.9-1.41.41.3-1.31.3-1.4-1.21.2-0.9-0.00.1
Degree of sensitization stereotypy0.40.51.20.7-0.7-0.70.7-0.80.70.5-1.10.20.8-0.2
Conditioned locomotion2.32.74.41.5-1.5-1.51.5-1.61.51.90.12.1-2.12.0
Cocaine response after cond. corrected0.20.20.30.5-0.5-0.50.5-0.50.50.5-0.40.4-0.2-0.1
Cocaine response after cond. not corrected0.30.40.50.7-0.7-0.70.6-0.60.60.7-0.40.7-0.50.3
Cocaine response before conditioning0.20.20.7-0.10.10.1-0.20.3-0.20.10.70.3-0.70.8
Saline control response0.00.10.50.1-0.1-0.10.0-0.0-0.10.10.10.2-0.10.7
Bone: connectivity density0.91.43.90.9-0.9-1.01.0-1.00.90.4-2.0-0.21.7-1.7
Bone: cortical apparent density0.70.91.31.2-1.2-1.01.0-1.01.01.1-0.61.1-0.30.9
Bone: cortical area0.50.82.5-0.90.90.8-0.80.8-0.7-0.51.1-0.2-0.41.6
Bone: cortical porosity0.10.10.2-0.40.40.3-0.30.3-0.3-0.4-0.2-0.40.1-0.3
Bone: cortical porosity0.10.10.4-0.40.40.2-0.20.2-0.2-0.20.2-0.0-0.60.2
Bone: cortical thickness0.71.23.1-1.11.11.1-1.11.1-1.0-0.71.4-0.3-0.41.8
Bone: cortical thickness0.10.10.40.1-0.1-0.10.1-0.10.0-0.1-0.6-0.20.5-0.3
Bone: cortical tissue density0.60.81.21.1-1.1-0.90.9-0.90.91.0-0.61.0-0.30.8
Condit. Reinf. active minus inactive responses1.41.52.2-1.41.41.4-1.51.4-1.4-1.31.2-1.20.3-0.4
Condit. Reinf. active-inactive response ratio0.30.40.6-0.50.50.6-0.60.6-0.6-0.70.2-0.70.6-0.8
Condit. Reinf. active responses2.32.83.9-1.91.91.9-2.01.9-1.9-1.91.3-1.70.8-0.5
Condit. Reinf. inactive responses1.82.23.1-1.71.71.8-1.71.6-1.6-1.70.8-1.60.8-0.5
Incentive salience index mean1.72.03.0-1.61.61.7-1.71.7-1.6-1.41.7-1.20.10.3
Condit. Reinf. lever presses3.04.05.6-2.32.32.4-2.32.3-2.2-2.12.1-1.70.50.3
Condit. Reinf. active minus inactive responses0.20.31.1-0.00.00.1-0.30.3-0.3-0.4-0.7-0.60.9-1.1
Condit. Reinf. active-inactive response ratio1.41.43.1-0.80.80.9-1.11.2-1.2-1.3-0.3-1.51.5-1.8
Condit. Reinf. active responses0.00.10.20.1-0.10.0-0.10.1-0.1-0.1-0.4-0.20.4-0.5
Condit. Reinf. inactive responses0.20.20.70.3-0.3-0.10.3-0.30.40.40.30.6-0.70.9
Condit. Reinf. lever presses0.60.81.6-0.80.80.9-0.80.9-0.9-1.0-0.2-1.21.3-1.0
Condit. Reinf. lever reinforcers received0.00.10.20.2-0.2-0.0-0.10.0-0.0-0.1-0.4-0.20.5-0.4
Conditioned reinforcement - actives1.31.32.70.9-0.9-1.01.0-1.01.21.30.71.5-1.21.6
Conditioned reinforcement - inactives0.70.83.2-1.01.00.8-0.70.8-0.5-0.51.8-0.2-0.60.8
Conditioned locomotion0.00.00.2-0.20.2-0.10.0-0.00.10.00.40.00.20.3
Patch foraging indifference point 0 sec0.71.11.6-1.11.11.3-1.21.1-1.1-1.10.9-1.10.4-0.7
Patch foraging indifference point AUC1.31.56.3-0.80.80.9-0.90.9-0.7-0.32.50.2-1.71.7
Delay disc. indifference point, 0s delay1.31.42.81.4-1.4-1.11.1-1.11.11.30.21.4-1.70.5
Delay disc. indifference point, 16s delay10.210.413.73.7-3.7-3.53.5-3.53.53.7-1.83.6-1.71.9
Delay disc. indifference point, 2s delay2.83.14.62.0-2.0-1.81.8-1.81.72.0-0.32.1-1.81.2
Delay disc. indifference point, 24s delay1.00.91.61.3-1.3-1.01.0-1.00.91.0-1.10.90.10.3
Delay disc. indifference point, 4s delay4.04.27.21.9-1.9-1.91.9-1.91.92.30.92.7-2.42.5
Delay disc. indifference point, 8s delay4.84.96.82.4-2.4-2.42.4-2.42.42.6-0.52.6-1.81.7
Indifference point function ln k0.30.50.70.7-0.7-0.70.8-0.80.70.8-0.40.7-0.6-0.2
Indifference point function log k0.30.50.70.7-0.7-0.70.8-0.80.70.8-0.40.7-0.6-0.2
Patch foraging total patch changes 0 sec0.81.42.1-1.31.31.4-1.31.2-1.2-1.31.2-1.10.3-0.7
Patch foraging total patch changes 12 sec0.81.13.3-1.01.01.1-1.10.9-0.9-0.71.8-0.3-0.61.3
Patch foraging total patch changes 18 sec1.21.64.7-1.21.21.5-1.31.2-1.1-1.02.2-0.6-0.81.1
Patch foraging total patch changes 24 sec0.70.82.3-1.01.01.2-0.90.9-0.7-0.81.5-0.5-0.40.5
Patch foraging total patch changes 6 sec1.62.44.0-1.71.72.0-1.81.8-1.7-1.61.4-1.40.50.1
Patch foraging time to switch 0 sec4.06.117.62.7-2.7-2.72.7-2.62.52.1-4.21.41.2-0.6
Patch foraging water rate 0 sec2.84.619.3-1.91.91.9-1.81.7-1.6-1.04.4-0.2-2.42.2
Patch foraging water rate 12 sec3.96.09.1-2.92.92.9-2.72.8-2.7-2.53.0-1.9-0.40.3
Patch foraging water rate 18 sec0.91.22.8-1.21.21.3-1.11.2-1.1-1.01.7-0.7-0.50.3
Patch foraging water rate 24 sec1.62.25.7-1.71.71.6-1.61.6-1.4-1.32.4-0.9-0.80.2
Patch foraging water rate 6 sec0.71.04.6-0.50.50.4-0.40.4-0.3-0.02.20.4-1.71.5
Seeking ratio, delayed vs. immediate footshock1.61.83.21.4-1.4-1.81.5-1.71.61.4-1.31.10.00.0
Distance traveled before self-admin0.10.10.4-0.40.40.2-0.10.2-0.1-0.20.6-0.1-0.40.4
Distance traveled after self-admin3.03.44.8-2.22.22.1-2.12.1-2.1-2.01.4-1.7-0.3-0.5
Extensor digitorum longus weight0.10.20.3-0.60.60.6-0.50.6-0.6-0.40.5-0.3-0.20.5
Bone: elastic displacement0.30.30.50.7-0.7-0.50.5-0.50.50.6-0.70.5-0.00.5
Bone: elastic work0.10.20.9-0.00.00.2-0.20.2-0.2-0.3-0.6-0.41.0-0.0
Bone: endosteal estimation0.30.71.20.9-0.9-1.01.1-1.11.00.8-0.80.60.0-0.4
Bone: endosteal perimeter0.00.00.0-0.10.1-0.00.1-0.10.1-0.00.1-0.00.1-0.1
Epididymis fat weight2.04.76.7-2.22.22.3-2.32.3-2.2-2.50.1-2.62.3-1.6
Delta time in closed arm before/after self-admin0.40.41.7-0.50.50.3-0.20.3-0.4-0.6-0.4-0.81.3-0.9
Delta time in open arm before/after self-admin0.60.62.40.6-0.6-0.60.6-0.60.80.70.20.8-1.50.4
Diff in mean of infusions in LGA sessions0.40.52.4-0.60.60.5-0.70.6-0.4-0.31.60.00.00.9
Delay discount exponential model param7.17.510.1-3.13.12.9-2.92.9-2.9-3.21.1-3.21.9-2.0
Extinction: sum of active levers before priming0.00.00.2-0.10.10.00.00.10.0-0.00.50.1-0.20.1
Active lever presses in extinction session 60.40.41.7-0.10.10.2-0.30.3-0.00.11.30.4-0.61.2
Bone: final force0.30.50.7-0.80.80.7-0.70.6-0.7-0.80.4-0.70.70.4
Bone: final moment0.30.40.8-0.70.70.7-0.60.6-0.6-0.60.8-0.40.10.9
Food consumed during 24 hour testing period0.50.62.2-0.70.70.8-0.90.8-0.7-0.41.5-0.1-0.90.6
Glucose4.36.49.1-2.82.82.8-2.92.8-3.0-2.91.3-2.81.4-1.4
Heart weight1.31.82.51.4-1.4-1.51.5-1.51.41.6-0.61.6-1.11.1
Delay discount hyperbolic model param6.56.99.5-3.03.02.8-2.82.8-2.7-3.00.9-3.12.0-2.0
Intermittent access intake day 1-15 change0.10.10.8-0.10.10.1-0.10.1-0.10.10.60.3-0.10.9
Intermittent access intake escalation0.00.00.20.1-0.1-0.10.1-0.00.10.1-0.00.20.20.4
Intermittent access intake escalation 20.20.21.1-0.20.20.1-0.10.2-0.10.10.60.3-0.41.0
Intermitt. access day 1 inactive lever presses1.11.21.7-1.31.31.3-1.21.3-1.1-1.21.0-1.00.2-0.3
Intermitt. access day 15 inactive lever presses1.41.52.4-1.51.51.4-1.31.4-1.3-1.31.4-1.1-0.0-0.3
Intermitt. access escalation Index0.00.00.30.0-0.0-0.1-0.1-0.10.00.0-0.2-0.0-0.2-0.5
Intermittent access day 1 total infusions0.70.91.3-1.11.10.8-0.80.8-0.8-1.00.2-1.11.1-1.0
Intermittent access day 15 total infusions0.40.40.9-0.80.80.5-0.50.5-0.5-0.70.3-0.70.9-0.5
Intermittent access terminal intake (last 3 days)0.30.31.2-0.60.60.3-0.30.3-0.3-0.6-0.1-0.71.1-0.5
Intermittent access total infusions0.30.31.1-0.50.50.3-0.30.3-0.2-0.5-0.2-0.71.1-0.8
Intermittent access day 1 locomotion0.50.51.3-0.70.70.6-0.50.4-0.5-0.8-0.2-1.00.5-1.2
Intermittent access day 15 total locomotion0.30.30.5-0.70.70.6-0.60.5-0.5-0.60.5-0.60.1-0.1
Intermittent access total locomotion0.30.31.3-0.30.30.2-0.20.1-0.2-0.5-0.7-0.70.9-1.2
Intermittent access standard deviation2.52.75.31.8-1.8-1.91.9-1.81.81.5-2.31.10.8-0.2
Left kidney weight0.30.83.1-0.50.50.5-0.40.5-0.5-0.01.50.4-1.21.7
Right kidney weight0.30.93.7-0.00.00.00.1-0.10.00.51.41.0-1.81.9
Cocaine induced anxiety0.20.20.5-0.30.30.4-0.40.4-0.4-0.5-0.2-0.60.5-0.7
Post-drug Anxiety0.30.31.60.1-0.10.1-0.10.1-0.1-0.2-1.0-0.51.3-0.9
Baseline Anxiety0.20.20.40.6-0.6-0.50.5-0.50.50.5-0.60.40.30.3
Tail length1.54.55.9-2.42.42.4-2.32.4-2.4-2.40.9-2.31.7-0.5
Length with tail0.10.41.9-0.40.40.4-0.40.4-0.5-0.6-0.5-0.71.40.4
Length without tail2.14.76.52.5-2.5-2.62.5-2.52.42.3-2.21.90.10.9
Times rat made contact with spout4.65.47.1-2.42.42.5-2.62.6-2.6-2.71.3-2.61.5-1.9
Lifetime Intake0.10.10.30.0-0.0-0.30.3-0.30.30.1-0.3-0.10.5-0.4
Liver weight, left0.40.61.9-0.70.70.6-0.80.8-0.8-0.41.4-0.1-0.91.0
Liver weight, right0.50.81.2-0.90.90.9-1.01.0-1.1-1.00.3-1.00.8-0.1
Locomotor activity2.13.44.9-1.81.81.9-2.22.1-2.2-2.10.2-2.11.8-1.0
Locomotor testing distance1.83.14.2-1.71.71.9-2.02.0-2.0-2.0-0.1-2.11.9-0.9
Locomotor testing rearing2.53.86.1-2.22.22.4-2.52.3-2.2-2.01.8-1.60.10.3
Locomotion in novel chamber0.70.91.21.0-1.0-1.11.1-1.11.11.1-0.21.1-0.60.8
Locomotion in novel chamber post-restriction1.92.33.71.2-1.2-1.31.4-1.41.51.71.11.9-1.91.7
Fecal boli incidents, locomotor time 11.11.23.00.8-0.8-0.70.7-0.70.91.00.91.3-1.61.7
Change in fecal boli incidents, locomotor task0.20.20.40.2-0.2-0.20.2-0.30.20.40.50.6-0.40.6
Time >=10cm from walls, locomotor time 10.30.31.5-0.50.50.4-0.40.4-0.3-0.31.2-0.1-0.70.5
Bouts of movement, locomotor time 10.20.21.30.1-0.1-0.30.3-0.20.3-0.2-0.8-0.4-0.2-1.1
Total resting periods, locomotor time 10.30.31.4-0.50.50.3-0.20.4-0.3-0.7-0.3-0.8-0.0-1.2
Rest time, locomotor task time 10.70.81.10.9-0.9-0.91.0-1.01.11.00.21.0-1.00.4
Distance moved, locomotor task time 10.10.10.3-0.20.20.2-0.30.3-0.4-0.2-0.6-0.30.4-0.4
Vertical activity count, locomotor time 10.40.50.80.9-0.9-0.70.7-0.70.60.8-0.60.7-0.00.5
Time >=10cm from walls, locomotor time 20.50.62.4-0.70.70.5-0.50.6-0.4-0.41.6-0.0-1.00.7
Bouts of movement, locomotor time 20.30.30.6-0.70.70.6-0.60.5-0.6-0.7-0.2-0.70.8-0.3
Total resting periods, locomotor time 20.20.20.9-0.30.30.2-0.20.1-0.2-0.4-0.5-0.51.0-0.4
Rest time, locomotor task time 20.50.60.90.8-0.8-0.91.0-0.90.90.6-0.80.40.4-0.4
Distance moved, locomotor task time 20.91.01.6-1.21.21.1-1.11.3-1.1-1.10.7-1.0-0.3-0.6
Vertical activity count, locomotor time 20.20.20.40.4-0.4-0.20.2-0.30.30.50.50.6-0.60.6
Light reinforcement 11.52.74.0-1.91.91.9-2.01.9-1.8-1.71.6-1.40.10.3
Light reinforcement 22.53.35.0-2.02.01.7-1.81.9-1.9-2.20.2-2.21.8-1.4
Bone: marrow area0.40.81.30.9-0.9-1.01.1-1.21.10.9-0.80.70.0-0.3
Bone: maximum diameter0.20.41.4-0.50.50.5-0.40.4-0.3-0.21.10.1-0.91.2
Bone: maximum force0.10.21.3-0.20.20.1-0.00.0-0.1-0.4-0.6-0.51.2-0.3
Bone: maximum moment0.00.00.3-0.10.10.00.0-0.1-0.0-0.1-0.2-0.20.60.2
Mean time between licks in bursts1.11.62.91.3-1.3-1.31.5-1.41.31.0-1.70.60.5-1.3
Mean num. licks in bursts0.70.92.10.8-0.8-0.80.8-0.70.81.00.41.2-1.51.1
Cd content in liver1.11.22.71.0-1.0-1.11.1-1.11.11.2-0.21.4-1.70.7
Co content in liver0.10.10.2-0.20.20.2-0.20.2-0.2-0.10.3-0.1-0.5-0.4
Cu content in liver1.01.23.00.9-0.9-0.90.8-0.90.91.20.71.4-1.71.5
Fe content in liver0.40.50.70.7-0.7-0.80.8-0.80.80.7-0.80.60.50.8
K content in liver1.31.25.10.6-0.6-0.60.6-0.60.40.0-2.3-0.51.8-1.7
Mg content in liver1.71.72.31.5-1.5-1.41.5-1.41.51.3-1.51.10.10.6
Mn content in liver1.01.12.8-1.01.01.1-1.01.1-1.0-1.10.7-1.10.1-1.7
Na content in liver0.10.10.5-0.10.10.2-0.20.2-0.2-0.10.3-0.10.40.7
Rb content in liver5.56.89.02.9-2.9-3.03.0-3.03.02.9-1.82.7-0.81.7
Se content in liver0.20.20.9-0.40.40.4-0.40.4-0.3-0.20.60.1-0.90.3
Sr content in liver0.60.61.0-0.90.90.9-0.90.9-0.8-0.71.0-0.4-0.60.0
Zn content in liver5.25.78.72.3-2.3-2.32.4-2.32.52.7-0.12.9-2.72.5
Bone: minimum diameter0.20.30.6-0.80.80.5-0.40.4-0.5-0.50.7-0.4-0.20.4
Time in familiar zone, hab. session 10.80.72.2-0.70.70.8-0.70.7-0.5-0.31.40.1-1.01.5
Time in novel zone, hab. session 10.60.60.90.9-0.9-1.00.9-0.90.70.6-0.70.40.1-0.9
Total zone transitions, hab. session 13.24.56.6-2.62.62.3-2.42.3-2.4-2.31.7-2.10.8-0.3
Total locomotion distance, hab. session 13.34.76.5-2.62.62.5-2.52.4-2.5-2.22.5-1.80.10.3
Locomotion velocity, hab. session 12.94.25.8-2.42.42.3-2.32.3-2.3-2.12.4-1.70.10.4
Time in familiar zone, hab. session 21.71.84.01.4-1.4-1.51.5-1.51.51.2-2.00.80.7-0.0
Time in novel zone, hab. session 20.50.52.4-0.60.60.6-0.60.6-0.6-0.31.5-0.1-1.00.2
Total zone transitions, hab. session 23.03.96.0-2.02.01.9-2.02.0-2.1-2.3-0.1-2.52.0-2.0
Total locomotion distance, hab. session 22.83.75.0-2.12.12.1-2.12.0-2.2-2.21.0-2.21.3-1.4
Locomotion velocity, hab. session 22.33.14.2-1.91.91.9-1.91.8-2.0-2.00.8-2.01.3-1.5
Novel to familiar place preference ratio0.10.10.2-0.20.20.4-0.30.4-0.3-0.30.4-0.30.0-0.1
Novelty place preference0.00.00.00.0-0.00.1-0.10.1-0.0-0.00.2-0.00.00.2
Time in novel zone, NPP test0.00.00.10.0-0.00.1-0.00.1-0.00.00.30.1-0.20.1
Total zone transitions, NPP test5.57.810.6-3.33.33.1-3.13.1-3.2-3.21.6-3.01.7-0.9
Total locomotion distance, NPP test5.06.98.9-2.92.92.9-2.92.9-3.0-3.01.8-2.81.6-1.2
Locomotion velocity, NPP test5.57.810.3-3.13.13.1-3.13.1-3.1-3.21.4-3.12.2-1.2
Intraocular pressure0.81.11.71.1-1.1-1.21.1-1.11.21.1-0.11.2-1.30.2
Delta distance traveled before/after self-admin4.44.87.1-2.42.42.5-2.72.5-2.6-2.51.0-2.30.5-1.5
Delta ambulatory time before/after self-admin3.64.05.9-2.22.22.3-2.42.2-2.3-2.31.0-2.10.4-1.4
Parametrial fat weight5.110.013.9-3.53.53.7-3.63.6-3.7-3.61.6-3.41.8-1.3
Pavlov. Cond. lever latency1.82.35.21.7-1.7-1.71.6-1.61.51.3-2.30.90.2-1.3
Pavlov. Cond. magazine entry latency0.91.24.5-0.90.90.8-0.80.8-0.7-0.32.10.2-1.41.7
Pavlov. Cond. change in total contacts1.61.74.7-1.51.51.4-1.31.2-1.3-1.12.2-0.7-0.60.7
Pavlov. Cond. index score2.02.67.0-1.71.71.7-1.71.6-1.5-1.22.6-0.7-0.61.6
Pavlov. Cond. latency score1.52.06.1-1.41.41.3-1.31.3-1.2-0.82.5-0.3-0.81.9
Pavlov. Cond. lever contacts2.53.05.6-2.02.02.0-1.91.8-1.8-1.62.4-1.20.01.1
Pavlov. Cond. magazine entry number1.51.95.31.5-1.5-1.41.4-1.31.20.9-2.30.50.7-1.3
Pavlov. Cond. intertrial magazine entries0.60.81.21.0-1.0-1.11.1-1.11.00.9-0.80.7-0.0-0.1
Pavlov. Cond. lever-magazine prob. diff.2.02.47.1-1.71.71.6-1.61.5-1.4-1.12.7-0.6-0.81.6
Pavlov. Cond. response bias3.13.87.5-2.32.32.2-2.22.1-2.0-1.82.7-1.3-0.31.0
Pavlov. Cond. lever latency2.43.24.61.9-1.9-1.91.7-1.81.92.1-0.22.2-2.11.3
Pavlov. Cond. magazine entry latency1.51.82.5-1.51.51.5-1.31.3-1.4-1.50.2-1.61.5-0.6
Pavlov. Cond. change in total contacts2.33.24.8-1.81.81.9-1.81.8-1.9-2.10.2-2.22.2-1.3
Pavlov. Cond. index score3.84.96.6-2.52.52.5-2.22.4-2.4-2.60.7-2.62.1-1.1
Pavlov. Cond. latency score4.25.27.0-2.52.52.5-2.32.4-2.5-2.60.7-2.62.2-1.2
Pavlov. Cond. lever contacts2.53.44.9-2.02.02.0-1.81.9-2.0-2.10.3-2.22.1-1.2
Pavlov. Cond. magazine entry number0.70.92.01.0-1.0-1.00.8-0.80.91.00.11.1-1.40.2
Pavlov. Cond. intertrial magazine entries0.00.10.50.0-0.0-0.0-0.10.0-0.10.10.30.2-0.70.0
Pavlov. Cond. lever-magazine prob. diff.3.95.06.8-2.42.42.5-2.22.3-2.4-2.60.7-2.62.3-1.2
Pavlov. Cond. response bias1.01.43.8-1.11.11.2-0.91.0-1.1-1.3-0.4-1.52.0-0.8
Time in closed arm before self-admin0.20.31.00.5-0.5-0.30.2-0.30.30.1-1.0-0.10.6-1.0
Time in closed arm after self-admin0.70.83.3-0.10.10.0-0.10.0-0.1-0.4-1.3-0.81.6-1.8
Time in open arm before self-admin1.92.14.1-1.81.81.5-1.41.5-1.6-1.32.0-0.90.01.0
Time in open arm after self-admin0.70.82.9-0.80.80.5-0.50.6-0.5-0.31.70.1-1.41.2
Bone: periosteal estimation0.10.10.6-0.20.20.1-0.00.0-0.00.00.70.2-0.50.8
Bone: periosteal perimeter0.40.61.1-1.01.00.9-0.80.8-0.9-0.80.6-0.70.40.5
Bone: post-yield work0.20.20.9-0.20.2-0.00.1-0.1-0.0-0.3-0.5-0.50.9-0.9
Progressive ratio test 1 active lever presses1.41.42.2-1.21.21.2-1.11.1-1.1-1.30.0-1.51.5-1.3
Progressive ratio test 1 breakpoint1.01.11.5-1.11.11.1-1.01.0-1.0-1.20.2-1.21.1-0.9
Progressive ratio test 1 inactive lever presses0.70.81.7-1.21.21.0-0.91.0-0.8-0.91.3-0.70.10.1
Progressive ratio test 2 active lever presses0.91.02.0-1.31.31.1-1.01.0-0.8-1.01.4-0.80.20.2
Progressive ratio test 2 breakpoint1.41.52.9-1.61.61.4-1.31.3-1.1-1.21.7-1.00.20.2
Progressive ratio test 2 inactive lever presses0.40.41.2-0.90.90.6-0.60.7-0.4-0.61.1-0.50.10.1
Incentive Sensitization - Responses0.90.92.4-1.21.21.0-1.01.0-0.7-0.91.6-0.6-0.10.3
Incentive Sensitization - Breakpoint0.90.92.4-1.21.21.0-1.11.0-0.8-0.91.6-0.6-0.20.4
Sum of active levers in priming session hrs 5-61.71.63.21.0-1.0-0.90.8-0.91.01.41.11.7-1.81.7
Progressive ratio0.60.71.01.0-1.0-0.80.9-0.80.80.8-1.00.70.50.7
Food seeking constrained by brief footshock0.10.10.4-0.20.20.3-0.30.2-0.3-0.3-0.6-0.40.6-0.4
Seeking ratio, punishment vs. effort0.50.60.9-1.01.00.8-0.90.9-0.9-0.80.5-0.7-0.4-0.5
Retroperitoneal fat weight1.24.06.3-2.32.32.3-2.32.3-2.2-1.82.5-1.3-0.61.0
Reaction time number correct0.71.03.20.3-0.3-0.30.5-0.40.50.81.81.1-1.71.6
Reaction time mean minus median0.10.20.60.5-0.5-0.40.2-0.20.30.3-0.80.20.60.3
Reaction time mean minus median AUC0.40.51.70.8-0.8-0.70.5-0.50.60.5-1.30.20.9-0.3
Reaction time num false alarms0.60.81.21.0-1.0-1.11.0-1.01.10.9-0.90.8-0.10.4
Reaction time num false alarms AUC0.40.60.90.9-0.9-0.90.8-0.81.00.9-0.60.8-0.30.6
Reaction time trials correct on left0.71.03.20.3-0.3-0.30.5-0.40.50.81.81.1-1.71.6
Reaction time trials on left0.60.93.00.3-0.3-0.20.4-0.30.50.71.71.1-1.61.5
Reaction time mean1.01.35.60.3-0.3-0.30.2-0.20.0-0.3-2.3-0.82.4-1.7
Reaction time mean AUC1.11.56.10.2-0.2-0.30.1-0.2-0.0-0.4-2.4-1.02.5-1.9
Median of all reaction times1.01.45.70.0-0.0-0.20.1-0.1-0.1-0.5-2.2-1.02.4-1.9
Reaction time omissions0.50.71.2-0.80.80.8-0.90.9-1.0-0.90.0-1.01.1-0.5
Reaction time false alarm rate0.60.83.00.9-0.9-1.00.8-0.90.90.7-1.70.40.6-0.3
Reaction time premature initiation rate0.81.01.4-1.21.21.1-1.21.1-1.1-1.10.8-1.00.4-0.3
Reaction time premature initiations0.71.03.7-1.11.11.1-1.01.0-0.9-0.81.9-0.4-0.60.7
Std. dev. reaction times0.60.94.20.4-0.4-0.40.2-0.30.2-0.0-1.9-0.42.0-0.8
Reaction time trials completed0.60.93.00.3-0.3-0.20.4-0.30.50.71.71.1-1.61.5
Reaction time trials AUC0.60.93.50.2-0.2-0.10.3-0.20.40.61.90.9-1.61.5
Run reversals in cocaine runway, females0.60.51.6-0.70.70.7-0.70.7-0.8-0.51.3-0.30.10.9
Run reversals in cocaine runway, males0.10.10.3-0.30.30.1-0.10.1-0.1-0.10.50.1-0.60.2
Latency to leave start box in cocaine runway1.61.73.0-1.71.71.4-1.41.4-1.3-1.21.6-1.0-0.50.4
Latency to leave start box in cocaine runway, F0.20.20.5-0.70.70.4-0.50.4-0.4-0.50.3-0.5-0.3-0.3
Latency to leave start box in cocaine runway, M3.83.66.2-2.22.22.1-2.12.1-2.1-1.82.5-1.3-0.20.8
Std. dev. time between licks in bursts1.61.93.31.4-1.4-1.41.7-1.81.71.5-0.61.4-0.90.3
Total sessions with >9 infusions0.10.10.4-0.10.1-0.10.2-0.20.20.20.60.3-0.20.5
Short access day 1 total inactive lever presses0.30.31.6-0.30.30.2-0.10.1-0.00.11.30.3-1.00.7
Short access day 10 total inactive lever presses0.80.82.5-1.01.00.9-1.00.9-0.8-0.71.6-0.3-0.80.6
Short access day 1 total infusions0.40.40.70.5-0.5-0.60.7-0.70.80.70.30.8-0.50.5
Short access day 10 total infusions0.30.31.4-0.20.20.10.00.00.0-0.3-0.7-0.61.2-0.9
Short access total infusions0.30.30.50.5-0.5-0.60.7-0.70.70.5-0.60.30.3-0.2
Short access day 1 locomotion0.50.50.90.7-0.7-0.90.9-0.90.90.8-0.40.7-0.10.3
Short access day 10 total locomotion1.61.84.81.5-1.5-1.41.4-1.61.31.1-2.20.60.5-0.8
Short access total locomotion1.61.72.71.4-1.4-1.51.5-1.61.51.4-0.91.3-0.70.4
One hour access (0.3 mA shock)0.60.71.90.5-0.5-0.60.6-0.60.70.80.71.1-1.11.4
Compulsive drug intake0.40.41.50.3-0.3-0.10.2-0.10.20.50.90.7-1.21.0
One hour access (shock baseline)0.20.20.4-0.60.60.4-0.50.4-0.4-0.60.0-0.60.6-0.4
Social response proportion0.80.91.80.9-0.9-1.11.2-1.11.00.9-1.40.70.40.2
Social responses2.02.53.61.7-1.7-1.81.8-1.91.91.7-1.51.40.31.0
Social time2.63.49.11.4-1.4-1.61.5-1.41.51.90.62.3-2.43.0
Soleus weight0.30.81.1-1.11.11.0-1.01.0-1.0-1.00.5-0.90.60.3
Bone: stiffness0.00.10.4-0.00.0-0.10.2-0.20.1-0.1-0.4-0.20.6-0.2
Tibialis anterior weight0.20.60.7-0.80.80.8-0.70.8-0.8-0.90.3-0.90.5-0.5
Time to tail flick, vehicle, before self-admin0.20.20.40.4-0.4-0.60.2-0.40.50.5-0.40.50.60.5
Time to tail flick, vehicle, after self-admin2.22.47.21.7-1.7-1.51.4-1.61.21.2-2.70.71.6-0.6
Time to tail flick, test, before self-admin5.15.07.42.2-2.2-2.42.2-2.32.42.6-0.12.7-2.21.9
Time to tail flick, test, after self-admin0.40.40.80.9-0.9-0.70.4-0.70.60.8-0.40.70.10.4
Delta time to tail flick, vehicle, before/after SA0.50.51.71.0-1.0-0.50.7-0.70.40.5-1.30.30.3-0.2
Delta time to tail flick, test, before/after SA2.82.57.8-1.01.01.2-1.31.2-1.3-1.6-1.1-2.02.8-2.0
Tibia length1.84.98.0-2.52.52.6-2.62.6-2.5-2.12.8-1.6-0.50.4
Ambulatory time before self-admin0.20.20.70.2-0.2-0.20.4-0.30.40.40.70.5-0.80.8
Ambulatory time after self-admin2.83.14.2-2.12.12.1-2.02.0-2.0-2.01.3-1.7-0.1-0.7
Bone: tissue strength0.10.10.40.4-0.4-0.30.3-0.30.20.40.10.4-0.20.6
Total heroin consumption0.10.10.5-0.50.5-0.1-0.00.00.0-0.30.3-0.30.7-0.1
Bone: trabecular number0.40.61.60.7-0.7-0.90.9-0.90.80.5-1.30.21.0-0.2
Bone: trabecular spacing0.50.72.3-0.70.70.7-0.80.8-0.7-0.41.5-0.0-1.20.8
Bone: trabecular thickness0.70.82.50.8-0.8-0.91.0-1.01.00.6-1.60.30.7-0.8
Bone: trabecular tissue density1.11.56.90.3-0.3-0.30.3-0.30.50.91.91.4-2.61.8
Water consumed over 24 hours1.61.93.1-1.51.51.6-1.71.6-1.5-1.31.8-0.9-0.20.8
Number of responses in last shaping day0.20.20.8-0.30.30.2-0.30.3-0.2-0.10.90.1-0.50.6