Hub : Genes

Mdga1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	Mdga1	0.06	0.06	1.9e-07	0.06	0.06	0.06	0.06	2.1e-07	8.2e-07	1.0e-06	6.4e-07
2	Eye	alternative TSS	XM_039098719.1	0.92	0.06	4.2e-03	0.12	0.09	0.06	0.1	7.7e-03	1.5e-02	4.1e-02	1.5e-02
3	BLA	gene expression	Mdga1	0.1	0.12	1.1e-03	0.04	0.06	0.05	0.06	3.3e-03	5.4e-04	1.5e-03	4.1e-04
4	Brain	gene expression	Mdga1	0.04	0.04	1.8e-03	0.03	0.02	0.01	0.03	8.8e-04	7.8e-03	7.1e-02	1.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
Bone: apparent density	0.8	1.3	1.4	1.2	1.2	-1.1	-1.1
Area under the delay curve	1.7	1.8	3.3	-1.8	-1.0	1.2	1.1
BMI with tail	2.9	9.4	10.8	-3.3	-2.9	3.1	2.9
BMI without tail	1.9	4.0	4.7	-2.2	-2.1	2.0	1.7
Body weight	6.6	27.8	32.3	-5.7	-5.5	5.0	4.8
Weight adjusted by age	4.2	4.7	6.7	-1.5	-2.6	2.3	2.2
Bone surface	0.0	0.0	0.0	-0.2	0.0	0.1	-0.0
Bone volume	0.0	0.0	0.0	-0.1	-0.0	0.2	-0.0
Breakpoint value in progressive ratio session	0.5	0.5	0.7	0.6	0.6	-0.8	-0.8
Number of licking bursts	0.5	0.6	0.9	0.9	0.8	-0.6	-0.6
Context. condit. distance diff. score	0.3	0.3	0.5	0.5	0.4	-0.7	-0.7
Locomotion velocity, session 1	1.8	2.0	2.9	0.7	1.3	-1.7	-1.6
Locomotion distance, session 1	3.3	4.2	4.5	2.1	2.1	-2.1	-2.0
Locomotion velocity, session 2	0.2	0.2	0.4	0.3	0.6	-0.5	-0.3
Locomotion distance, session 2	0.7	0.9	1.2	1.1	0.9	-0.9	-0.9
Locomotion velocity, session 3	0.0	0.0	0.1	-0.1	0.0	-0.3	0.1
Locomotion distance, session 3	0.7	0.8	0.9	0.9	0.9	-1.0	-0.7
Stereotopy head waving bouts, day 3	1.2	1.4	1.6	-1.3	-1.3	1.1	1.1
Stereotopy head waving duration, day 3	0.4	0.5	0.6	-0.6	-0.7	0.6	0.8
Locomotion velocity, session 7	0.2	0.2	0.5	0.7	0.5	-0.0	-0.2
Locomotion distance, session 7	0.9	1.2	2.5	1.6	1.1	-0.8	-0.7
Stereotopy head waving bouts, day 7	0.1	0.1	0.3	-0.5	-0.1	0.2	0.4
Stereotopy head waving duration, day 7	0.6	0.7	0.8	-0.9	-0.6	0.9	0.9
Locomotion velocity, session 8	0.0	0.1	0.1	-0.1	-0.1	-0.3	-0.3
Locomotion distance, session 8	0.6	0.8	1.1	1.0	0.7	-0.9	-0.9
Degree of sensitization distance	0.2	0.2	0.5	0.0	-0.5	0.7	0.5
Degree of sensitization stereotypy	0.2	0.2	0.4	0.3	0.6	-0.5	-0.2
Conditioned locomotion	1.9	2.2	3.3	-1.4	-1.8	1.5	1.2
Cocaine response after cond. corrected	1.6	1.8	2.2	-1.4	-1.5	1.4	1.0
Cocaine response after cond. not corrected	1.3	1.5	2.2	-1.5	-1.3	1.2	0.8
Cocaine response before conditioning	0.2	0.2	0.4	0.1	0.5	-0.6	-0.4
Saline control response	0.5	0.6	1.1	-0.9	-1.0	0.5	0.5
Bone: connectivity density	0.6	0.9	1.1	0.9	1.0	-0.9	-1.0
Bone: cortical apparent density	0.0	0.1	0.2	0.0	0.4	-0.1	-0.1
Bone: cortical area	0.9	1.3	1.9	-1.4	-1.1	1.0	1.0
Bone: cortical porosity	0.0	0.0	0.1	-0.2	0.0	0.1	0.1
Bone: cortical porosity	0.0	0.0	0.1	-0.2	-0.1	0.2	0.3
Bone: cortical thickness	0.0	0.0	0.1	-0.3	0.1	-0.1	-0.0
Bone: cortical thickness	0.0	0.0	0.1	0.2	-0.3	0.0	0.0
Bone: cortical tissue density	0.0	0.0	0.1	-0.1	0.3	-0.0	-0.1
Condit. Reinf. active minus inactive responses	1.3	1.5	1.8	0.9	1.2	-1.3	-1.3
Condit. Reinf. active-inactive response ratio	0.1	0.1	0.2	0.0	0.4	-0.4	-0.5
Condit. Reinf. active responses	0.9	1.0	1.4	0.7	1.0	-1.2	-1.2
Condit. Reinf. inactive responses	1.0	1.2	1.5	0.9	1.0	-1.2	-1.2
Incentive salience index mean	0.5	0.6	0.8	0.5	0.8	-0.9	-0.9
Condit. Reinf. lever presses	0.0	0.0	0.0	-0.1	0.1	-0.2	-0.2
Condit. Reinf. active minus inactive responses	2.0	2.5	3.6	1.0	1.4	-1.9	-1.9
Condit. Reinf. active-inactive response ratio	0.8	0.8	1.5	0.5	0.6	-1.2	-1.1
Condit. Reinf. active responses	1.6	2.3	3.4	1.1	1.4	-1.8	-1.6
Condit. Reinf. inactive responses	0.1	0.1	0.1	0.2	0.3	-0.3	-0.3
Condit. Reinf. lever presses	5.0	6.8	8.2	2.6	2.4	-2.9	-2.6
Condit. Reinf. lever reinforcers received	2.6	3.7	5.1	1.6	1.8	-2.3	-2.0
Conditioned reinforcement - actives	0.1	0.1	0.3	-0.3	-0.5	0.3	0.3
Conditioned reinforcement - inactives	0.5	0.6	0.7	0.9	0.6	-0.7	-0.8
Conditioned locomotion	0.5	0.6	0.9	-0.4	-0.9	0.9	0.8
Patch foraging indifference point 0 sec	0.4	0.6	0.9	-0.0	-0.9	0.9	0.7
Patch foraging indifference point AUC	0.2	0.2	0.3	0.5	0.4	-0.6	-0.3
Delay disc. indifference point, 0s delay	1.5	1.7	2.2	-1.1	-1.3	1.3	1.5
Delay disc. indifference point, 16s delay	0.4	0.4	1.0	-1.0	0.2	-0.4	-0.6
Delay disc. indifference point, 2s delay	0.2	0.2	0.4	-0.1	-0.2	0.6	0.6
Delay disc. indifference point, 24s delay	2.9	2.8	6.2	-2.5	-1.4	1.4	1.1
Delay disc. indifference point, 4s delay	2.1	2.2	2.7	-1.6	-1.4	1.5	1.3
Delay disc. indifference point, 8s delay	2.0	2.0	2.9	-1.7	-1.3	1.3	1.3
Indifference point function ln k	0.1	0.1	0.2	0.4	-0.0	0.4	0.1
Indifference point function log k	0.1	0.1	0.2	0.4	-0.0	0.4	0.1
Patch foraging total patch changes 0 sec	0.4	0.6	1.0	0.1	-0.9	1.0	0.8
Patch foraging total patch changes 12 sec	0.1	0.2	0.5	0.7	0.0	-0.3	-0.1
Patch foraging total patch changes 18 sec	0.2	0.2	0.3	-0.4	-0.5	0.5	0.6
Patch foraging total patch changes 24 sec	0.3	0.3	0.7	0.8	0.7	-0.3	-0.2
Patch foraging total patch changes 6 sec	0.0	0.1	0.2	0.1	-0.4	0.1	0.2
Patch foraging time to switch 0 sec	0.8	1.3	2.6	-1.6	-1.1	0.7	0.8
Patch foraging water rate 0 sec	0.2	0.4	0.9	1.0	-0.1	0.7	0.4
Patch foraging water rate 12 sec	0.0	0.1	0.3	0.5	-0.1	0.0	-0.1
Patch foraging water rate 18 sec	0.6	0.8	1.0	1.0	1.0	-0.7	-0.9
Patch foraging water rate 24 sec	0.2	0.2	0.7	0.8	0.1	-0.1	-0.4
Patch foraging water rate 6 sec	0.1	0.1	0.2	0.4	-0.3	0.3	0.0
Seeking ratio, delayed vs. immediate footshock	0.8	0.9	1.2	-0.6	1.0	-1.1	-1.0
Distance traveled before self-admin	0.8	0.8	1.1	-0.5	-0.9	1.1	1.1
Distance traveled after self-admin	0.1	0.1	0.1	-0.3	-0.1	0.3	0.2
Extensor digitorum longus weight	0.2	1.0	1.3	1.1	0.7	-1.0	-1.0
Bone: elastic displacement	0.1	0.2	0.3	-0.2	0.5	-0.5	-0.3
Bone: elastic work	0.1	0.1	0.4	-0.6	-0.2	0.2	0.4
Bone: endosteal estimation	3.1	6.8	7.3	-2.6	-2.7	2.6	2.6
Bone: endosteal perimeter	2.2	4.5	5.0	-2.2	-2.2	2.1	2.0
Epididymis fat weight	1.7	4.0	6.0	-2.3	-2.4	1.5	1.6
Delta time in closed arm before/after self-admin	2.8	2.7	4.2	-1.4	-2.0	1.6	1.5
Delta time in open arm before/after self-admin	1.1	1.1	1.2	1.0	1.1	-0.9	-1.1
Diff in mean of infusions in LGA sessions	0.6	0.7	1.0	1.0	0.8	-0.8	-0.7
Delay discount exponential model param	1.4	1.4	2.8	1.7	0.9	-1.1	-1.0
Extinction: sum of active levers before priming	0.4	0.4	0.6	0.7	-0.2	-0.6	-0.8
Active lever presses in extinction session 6	0.2	0.2	0.4	-0.4	-0.0	-0.5	-0.6
Bone: final force	4.6	7.5	8.7	-2.9	-2.7	2.6	2.7
Bone: final moment	3.9	6.3	7.4	-2.7	-2.4	2.4	2.5
Food consumed during 24 hour testing period	0.6	0.8	1.2	-1.1	-1.0	0.8	0.6
Glucose	0.4	0.6	0.9	-0.8	-0.6	0.7	0.9
Heart weight	1.2	1.6	2.2	1.4	1.5	-1.0	-1.1
Delay discount hyperbolic model param	1.0	1.1	2.1	1.4	0.8	-1.0	-0.9
Intermittent access intake day 1-15 change	0.1	0.1	0.1	-0.3	0.2	-0.2	-0.2
Intermittent access intake escalation	0.1	0.1	0.4	-0.6	-0.0	-0.1	-0.1
Intermittent access intake escalation 2	0.9	0.9	1.1	0.8	1.0	-1.0	-1.0
Intermitt. access day 1 inactive lever presses	0.2	0.3	0.3	0.6	-0.5	0.5	0.4
Intermitt. access day 15 inactive lever presses	0.2	0.2	0.8	-0.9	-0.3	0.1	0.2
Intermitt. access escalation Index	0.2	0.2	0.3	0.0	0.6	-0.4	-0.4
Intermittent access day 1 total infusions	0.4	0.5	1.1	0.5	1.0	-0.7	-0.5
Intermittent access day 15 total infusions	0.1	0.1	0.3	-0.0	0.5	-0.3	-0.1
Intermittent access terminal intake (last 3 days)	0.1	0.1	0.2	-0.1	0.0	0.2	0.4
Intermittent access total infusions	0.2	0.2	0.6	0.4	0.8	-0.3	-0.1
Intermittent access day 1 locomotion	0.1	0.1	0.2	-0.1	-0.1	0.5	0.4
Intermittent access day 15 total locomotion	1.4	1.5	3.0	-1.7	-1.2	1.0	0.9
Intermittent access total locomotion	0.3	0.4	1.0	-1.0	-0.3	0.5	0.4
Intermittent access standard deviation	0.6	0.6	0.8	-0.4	-0.7	0.9	0.9
Left kidney weight	2.4	6.8	8.4	-2.9	-2.3	2.6	2.6
Right kidney weight	3.1	8.6	9.7	-3.1	-2.7	3.0	2.9
Cocaine induced anxiety	0.3	0.4	0.7	0.4	0.6	-0.5	-0.8
Post-drug Anxiety	0.8	0.8	1.6	0.5	0.7	-1.0	-1.3
Baseline Anxiety	0.0	0.0	0.1	0.2	-0.3	0.1	0.1
Tail length	1.0	3.0	4.1	-1.6	-2.0	1.7	1.5
Length with tail	1.8	6.6	8.4	-2.7	-2.9	2.4	2.2
Length without tail	1.3	2.9	3.7	-1.9	-1.9	1.5	1.5
Times rat made contact with spout	4.7	5.4	5.8	2.4	2.3	-2.2	-2.4
Lifetime Intake	0.0	0.1	0.1	0.1	0.2	0.2	0.3
Liver weight, left	2.8	4.6	5.7	-2.1	-2.4	2.1	1.9
Liver weight, right	2.0	3.3	4.5	-1.3	-1.8	2.1	1.9
Locomotor activity	0.3	0.4	0.8	-0.4	-0.9	0.6	0.6
Locomotor testing distance	0.4	0.6	1.4	-0.3	-1.2	0.8	0.7
Locomotor testing rearing	1.4	2.2	2.6	-1.4	-1.6	1.4	1.5
Locomotion in novel chamber	0.1	0.1	0.1	0.0	0.2	0.3	0.3
Locomotion in novel chamber post-restriction	1.9	2.3	2.5	-1.6	-1.4	1.5	1.6
Fecal boli incidents, locomotor time 1	0.0	0.0	0.0	-0.2	0.1	0.0	-0.0
Change in fecal boli incidents, locomotor task	3.1	2.9	4.0	-0.4	-2.0	1.9	2.0
Time >=10cm from walls, locomotor time 1	3.1	3.1	3.9	-1.3	-1.9	1.8	2.0
Bouts of movement, locomotor time 1	0.8	0.9	1.3	0.7	0.9	-1.0	-1.2
Total resting periods, locomotor time 1	0.6	0.7	1.1	0.5	0.7	-0.9	-1.1
Rest time, locomotor task time 1	0.1	0.1	0.2	-0.1	-0.5	0.4	0.3
Distance moved, locomotor task time 1	0.1	0.1	0.2	-0.4	-0.1	-0.1	0.1
Vertical activity count, locomotor time 1	0.5	0.5	0.9	-1.0	-0.7	0.6	0.6
Time >=10cm from walls, locomotor time 2	12.5	13.2	16.1	-2.7	-3.8	3.9	4.0
Bouts of movement, locomotor time 2	0.2	0.2	0.5	-0.1	0.1	-0.5	-0.7
Total resting periods, locomotor time 2	0.4	0.4	0.8	0.3	0.3	-0.7	-0.9
Rest time, locomotor task time 2	0.0	0.0	0.1	-0.0	-0.3	0.1	0.0
Distance moved, locomotor task time 2	1.7	2.0	2.4	-1.4	-1.4	1.3	1.6
Vertical activity count, locomotor time 2	1.4	1.5	1.8	-1.0	-1.2	1.3	1.3
Light reinforcement 1	2.2	4.0	4.8	-1.8	-2.2	2.1	2.0
Light reinforcement 2	2.3	3.1	3.7	-1.9	-1.5	1.9	1.7
Bone: marrow area	3.3	7.1	7.6	-2.6	-2.8	2.6	2.6
Bone: maximum diameter	1.0	1.8	2.3	-1.5	-1.3	1.3	1.3
Bone: maximum force	1.8	3.1	3.6	-1.9	-1.8	1.7	1.7
Bone: maximum moment	1.3	2.2	2.7	-1.7	-1.5	1.4	1.4
Mean time between licks in bursts	0.6	0.8	1.5	0.6	1.2	-0.8	-0.8
Mean num. licks in bursts	0.6	0.7	1.0	0.7	0.7	-0.9	-1.0
Cd content in liver	0.5	0.6	0.9	-0.8	-0.5	0.7	0.9
Co content in liver	2.3	2.7	3.5	-1.5	-1.9	1.6	1.6
Cu content in liver	2.2	2.7	4.6	2.1	1.6	-1.4	-1.3
Fe content in liver	3.0	3.6	4.1	-2.0	-1.9	1.8	1.8
K content in liver	0.8	0.8	1.5	1.2	0.8	-0.7	-0.8
Mg content in liver	1.4	1.4	2.2	1.5	1.1	-1.0	-1.0
Mn content in liver	0.0	0.0	0.1	0.2	-0.0	0.1	0.1
Na content in liver	0.3	0.3	0.6	0.7	0.7	-0.4	-0.5
Rb content in liver	0.2	0.2	0.2	-0.4	-0.4	0.5	0.5
Se content in liver	1.7	2.0	2.9	1.7	1.4	-1.3	-1.2
Sr content in liver	0.0	0.0	0.0	0.0	-0.0	0.0	0.0
Zn content in liver	4.0	4.5	5.4	-1.6	-2.3	2.1	2.3
Bone: minimum diameter	2.4	4.5	5.2	-2.3	-2.1	2.0	2.1
Time in familiar zone, hab. session 1	0.3	0.3	0.5	-0.1	0.5	-0.7	-0.7
Time in novel zone, hab. session 1	1.0	0.9	1.3	-0.5	-1.0	1.1	1.1
Total zone transitions, hab. session 1	3.2	4.5	5.0	2.2	2.1	-2.1	-2.0
Total locomotion distance, hab. session 1	2.1	2.9	3.4	1.7	1.7	-1.8	-1.6
Locomotion velocity, hab. session 1	1.8	2.6	3.0	1.7	1.6	-1.7	-1.5
Time in familiar zone, hab. session 2	0.8	0.8	1.1	1.0	1.0	-0.7	-0.8
Time in novel zone, hab. session 2	0.4	0.4	0.7	-0.8	-0.8	0.4	0.5
Total zone transitions, hab. session 2	0.2	0.3	0.9	1.0	0.4	-0.3	-0.2
Total locomotion distance, hab. session 2	1.8	2.4	3.8	2.0	1.5	-1.4	-1.3
Locomotion velocity, hab. session 2	2.1	2.8	4.7	2.2	1.6	-1.5	-1.3
Novel to familiar place preference ratio	0.6	0.6	1.1	-0.7	-1.0	0.6	0.7
Novelty place preference	0.5	0.5	1.0	-0.6	-1.0	0.5	0.6
Time in novel zone, NPP test	0.4	0.4	0.8	-0.7	-0.9	0.3	0.5
Total zone transitions, NPP test	1.0	1.5	2.8	1.7	1.1	-1.0	-0.9
Total locomotion distance, NPP test	0.8	1.1	2.2	1.5	1.0	-0.7	-0.8
Locomotion velocity, NPP test	1.0	1.5	3.3	1.8	1.1	-0.8	-0.8
Intraocular pressure	0.6	0.8	1.5	-1.2	-1.0	0.7	0.7
Delta distance traveled before/after self-admin	0.5	0.5	0.8	0.4	0.7	-0.7	-0.9
Delta ambulatory time before/after self-admin	0.6	0.7	1.0	0.5	0.9	-0.9	-1.0
Parametrial fat weight	0.5	0.9	1.7	-1.3	-1.1	0.6	0.6
Pavlov. Cond. lever latency	0.1	0.1	0.2	-0.5	-0.3	0.2	0.1
Pavlov. Cond. magazine entry latency	0.3	0.3	0.5	0.7	0.6	-0.5	-0.5
Pavlov. Cond. change in total contacts	0.2	0.2	0.6	-0.7	-0.4	0.2	0.2
Pavlov. Cond. index score	0.0	0.0	0.0	0.1	-0.0	0.0	-0.0
Pavlov. Cond. latency score	0.1	0.1	0.1	0.0	-0.3	0.3	0.3
Pavlov. Cond. lever contacts	0.0	0.1	0.1	0.3	0.2	-0.2	-0.2
Pavlov. Cond. magazine entry number	0.6	0.8	0.9	-0.9	-0.9	0.8	0.9
Pavlov. Cond. intertrial magazine entries	0.4	0.4	0.6	0.4	0.8	-0.8	-0.6
Pavlov. Cond. lever-magazine prob. diff.	0.0	0.0	0.0	0.1	-0.0	0.0	0.0
Pavlov. Cond. response bias	1.1	1.3	1.6	0.9	1.2	-1.2	-1.3
Pavlov. Cond. lever latency	2.9	3.9	4.7	-2.0	-1.8	2.2	1.9
Pavlov. Cond. magazine entry latency	0.1	0.1	0.1	-0.3	0.2	-0.3	-0.2
Pavlov. Cond. change in total contacts	2.4	3.4	3.8	1.8	1.7	-1.9	-1.9
Pavlov. Cond. index score	1.4	1.8	2.5	1.2	1.3	-1.6	-1.4
Pavlov. Cond. latency score	1.0	1.2	1.7	0.9	1.0	-1.3	-1.1
Pavlov. Cond. lever contacts	2.8	3.8	4.6	2.0	1.7	-2.1	-1.9
Pavlov. Cond. magazine entry number	0.1	0.1	0.1	-0.1	-0.4	0.3	0.2
Pavlov. Cond. intertrial magazine entries	0.3	0.5	1.2	1.1	0.4	-0.5	-0.4
Pavlov. Cond. lever-magazine prob. diff.	1.0	1.2	1.8	0.9	1.0	-1.3	-1.1
Pavlov. Cond. response bias	2.1	2.9	3.7	1.6	1.5	-1.9	-1.7
Time in closed arm before self-admin	0.2	0.2	0.5	0.7	-0.0	0.3	0.6
Time in closed arm after self-admin	0.6	0.6	0.9	-0.5	-1.0	0.7	0.9
Time in open arm before self-admin	1.4	1.5	2.2	0.6	1.5	-1.4	-1.3
Time in open arm after self-admin	3.8	4.2	5.7	1.7	2.4	-1.9	-2.1
Bone: periosteal estimation	2.6	5.4	6.0	-2.5	-2.4	2.2	2.2
Bone: periosteal perimeter	1.3	2.2	3.0	-1.7	-1.4	1.3	1.4
Bone: post-yield work	0.1	0.2	0.2	-0.4	-0.5	0.5	0.4
Progressive ratio test 1 active lever presses	0.0	0.0	0.1	0.2	0.1	-0.2	-0.1
Progressive ratio test 1 breakpoint	0.0	0.0	0.1	0.2	-0.1	0.0	0.1
Progressive ratio test 1 inactive lever presses	0.2	0.2	0.4	-0.7	-0.5	0.2	-0.0
Progressive ratio test 2 active lever presses	0.4	0.5	0.7	0.5	0.5	-0.8	-0.8
Progressive ratio test 2 breakpoint	0.4	0.4	0.6	0.5	0.6	-0.8	-0.7
Progressive ratio test 2 inactive lever presses	1.2	1.4	1.5	1.2	1.1	-1.2	-1.2
Incentive Sensitization - Responses	2.5	2.5	3.0	1.3	1.6	-1.7	-1.6
Incentive Sensitization - Breakpoint	1.9	1.9	2.4	1.0	1.4	-1.6	-1.4
Sum of active levers in priming session hrs 5-6	0.6	0.6	0.8	0.5	0.7	-0.9	-0.9
Progressive ratio	1.3	1.5	3.4	-1.8	-1.0	0.8	1.0
Food seeking constrained by brief footshock	0.0	0.0	0.1	-0.2	0.2	-0.2	0.0
Seeking ratio, punishment vs. effort	0.4	0.5	1.5	1.2	0.4	-0.3	-0.4
Retroperitoneal fat weight	1.4	4.7	7.1	-2.1	-2.7	2.1	1.8
Reaction time number correct	0.0	0.0	0.1	-0.2	-0.1	0.0	-0.3
Reaction time mean minus median	0.4	0.5	0.8	-0.2	0.7	-0.9	-0.8
Reaction time mean minus median AUC	0.3	0.3	0.4	-0.6	0.6	-0.6	-0.5
Reaction time num false alarms	0.3	0.4	1.2	1.1	0.6	-0.3	-0.2
Reaction time num false alarms AUC	0.7	1.0	2.5	1.6	1.0	-0.6	-0.4
Reaction time trials correct on left	0.0	0.0	0.1	-0.2	-0.1	0.0	-0.3
Reaction time trials on left	0.0	0.0	0.1	-0.2	-0.1	-0.0	-0.4
Reaction time mean	0.1	0.1	0.3	-0.6	-0.2	-0.1	0.0
Reaction time mean AUC	0.2	0.2	0.7	-0.8	-0.3	0.1	0.2
Median of all reaction times	0.2	0.2	0.5	-0.7	-0.5	0.3	0.4
Reaction time omissions	0.3	0.5	0.9	0.0	0.7	-0.9	-0.7
Reaction time false alarm rate	0.6	0.8	2.2	1.5	0.9	-0.5	-0.2
Reaction time premature initiation rate	0.0	0.1	0.1	0.3	-0.1	-0.3	-0.3
Reaction time premature initiations	0.0	0.1	0.1	-0.0	-0.3	-0.2	-0.3
Std. dev. reaction times	0.2	0.3	0.5	-0.3	0.4	-0.7	-0.6
Reaction time trials completed	0.0	0.0	0.1	-0.2	-0.1	-0.0	-0.4
Reaction time trials AUC	0.0	0.0	0.1	-0.2	-0.0	-0.0	-0.3
Run reversals in cocaine runway, females	0.1	0.1	0.1	-0.3	0.0	-0.2	-0.3
Run reversals in cocaine runway, males	1.1	1.0	1.7	0.1	1.1	-1.0	-1.3
Latency to leave start box in cocaine runway	0.1	0.2	0.5	0.3	-0.7	-0.1	-0.2
Latency to leave start box in cocaine runway, F	0.1	0.1	0.4	0.1	-0.6	-0.2	-0.2
Latency to leave start box in cocaine runway, M	0.1	0.1	0.3	0.1	-0.5	0.3	0.4
Std. dev. time between licks in bursts	1.3	1.5	1.6	-1.3	-1.2	1.2	1.2
Total sessions with >9 infusions	0.1	0.1	0.2	-0.0	-0.4	0.3	0.3
Short access day 1 total inactive lever presses	0.1	0.1	0.3	0.3	0.5	-0.3	-0.3
Short access day 10 total inactive lever presses	0.0	0.0	0.0	0.1	0.1	-0.1	-0.2
Short access day 1 total infusions	0.8	0.8	1.6	1.3	1.0	-0.6	-0.6
Short access day 10 total infusions	0.1	0.1	0.2	0.4	0.4	0.1	0.2
Short access total infusions	0.1	0.1	0.1	0.2	-0.0	0.4	0.4
Short access day 1 locomotion	0.0	0.0	0.0	0.2	-0.0	0.2	0.1
Short access day 10 total locomotion	0.6	0.6	1.8	1.3	-0.4	0.6	0.5
Short access total locomotion	0.6	0.6	1.0	0.3	-0.6	1.0	0.9
One hour access (0.3 mA shock)	1.8	2.1	2.4	1.4	1.6	-1.5	-1.3
Compulsive drug intake	0.9	0.9	1.9	1.4	0.8	-0.7	-0.6
One hour access (shock baseline)	0.3	0.4	0.6	-0.1	0.8	-0.7	-0.6
Social response proportion	1.3	1.4	3.1	-0.2	-0.7	1.4	1.8
Social responses	0.2	0.3	0.9	-0.1	-0.2	0.5	0.9
Social time	0.5	0.6	0.8	0.7	0.9	-0.9	-0.7
Soleus weight	0.8	2.4	2.8	-1.4	-1.7	1.6	1.6
Bone: stiffness	1.3	2.0	2.1	-1.3	-1.5	1.5	1.4
Tibialis anterior weight	0.8	2.6	3.0	1.6	1.4	-1.7	-1.7
Time to tail flick, vehicle, before self-admin	0.7	0.7	2.0	-1.4	-0.7	0.5	0.4
Time to tail flick, vehicle, after self-admin	0.1	0.1	0.2	0.0	-0.0	0.3	0.5
Time to tail flick, test, before self-admin	0.2	0.2	0.3	0.3	0.5	-0.5	-0.4
Time to tail flick, test, after self-admin	0.6	0.6	1.0	0.1	1.0	-0.9	-0.8
Delta time to tail flick, vehicle, before/after SA	0.2	0.2	0.5	0.7	0.5	-0.3	-0.0
Delta time to tail flick, test, before/after SA	0.8	0.8	1.1	-1.1	-0.7	0.9	0.8
Tibia length	2.0	5.6	6.2	-2.5	-2.2	2.3	2.4
Ambulatory time before self-admin	0.2	0.2	0.2	-0.3	-0.4	0.4	0.4
Ambulatory time after self-admin	0.3	0.4	0.6	0.2	0.8	-0.5	-0.8
Bone: tissue strength	0.0	0.0	0.1	0.2	0.1	0.1	0.2
Total heroin consumption	1.5	1.8	2.1	1.3	1.4	-1.4	-1.2
Bone: trabecular number	1.1	1.6	1.9	1.4	1.2	-1.3	-1.3
Bone: trabecular spacing	2.6	3.4	4.0	-1.5	-1.9	1.9	2.0
Bone: trabecular thickness	0.0	0.0	0.1	-0.3	-0.1	0.1	-0.0
Bone: trabecular tissue density	0.1	0.1	0.3	0.3	0.6	-0.2	-0.0
Water consumed over 24 hours	0.9	1.1	1.7	0.7	1.0	-1.0	-1.3
Number of responses in last shaping day	0.4	0.4	0.7	0.9	-0.6	0.5	0.6