Hub : Genes

Matk

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL intron excision ratio chr7_8461466_8462372 0.02 0.02 2.1e-03 0.01 0.01 0.01 0.01 3.6e-02 2.0e-02 9.3e-03 3.5e-02
2 PL gene expression Matk 0.06 0.04 5.4e-07 0.07 0.06 0.06 0.06 1.0e-07 2.7e-07 1.2e-07 1.7e-07
3 OFC gene expression Matk 0.24 0.16 3.5e-04 0.11 0.06 0.07 0.07 1.6e-03 1.8e-02 8.7e-03 8.4e-03
4 IL gene expression Matk 0.15 0.11 2.8e-03 0.06 0.08 0.05 0.07 1.3e-02 5.0e-03 2.9e-02 7.9e-03
5 BLA gene expression Matk 0.08 0.06 2.9e-05 0.08 0.08 0.08 0.07 6.8e-05 3.2e-05 4.3e-05 8.0e-05
6 PL isoform ratio NM_021859.2 0.03 0.02 4.6e-04 0.02 0.02 0.02 0.02 5.4e-03 1.2e-03 1.8e-03 5.7e-03
7 PL mRNA stability Matk 0.02 0.02 2.3e-03 0.02 0.02 0.02 0.02 6.5e-03 2.5e-03 4.9e-03 3.5e-03
8 NAcc isoform ratio XM_039079841.1 0.02 0.01 5.2e-03 0.01 0.01 0.01 0.01 1.9e-02 9.8e-03 2.8e-02 1.0e-02
9 NAcc alternative TSS XM_039079842.1 0.02 0.02 9.9e-03 0.02 0.02 0.01 0.02 4.1e-03 4.2e-03 8.3e-03 5.1e-03
10 NAcc gene expression Matk 0.04 0.03 3.6e-06 0.05 0.05 0.05 0.05 1.2e-06 1.9e-06 3.1e-06 1.8e-06
11 NAcc isoform ratio NM_021859.2 0.03 0.02 5.0e-04 0.02 0.02 0.02 0.02 1.2e-03 1.3e-03 3.2e-03 1.2e-03
12 LHb gene expression Matk 0.35 0.18 3.9e-06 0.21 0.13 0.14 0.16 8.5e-06 5.8e-04 3.2e-04 1.4e-04
13 LHb isoform ratio NM_021859.2 0.11 0.09 4.7e-03 0.1 0.09 0.1 0.09 1.8e-03 3.8e-03 2.4e-03 3.1e-03
14 NAcc alternative TSS XM_039079845.1 0.02 0.02 1.5e-03 0.02 0.02 0.02 0.02 7.4e-04 1.2e-03 3.9e-03 1.5e-03
15 IL isoform ratio NM_021859.2 0.15 0.12 9.0e-03 -0 -0 -0 0 3.7e-01 3.6e-01 3.5e-01 3.0e-01
16 NAcc alternative TSS XM_039079843.1 0.02 0.01 7.2e-03 0.01 0.01 0.01 0.01 6.2e-03 1.3e-02 4.1e-02 1.0e-02
17 NAcc mRNA stability Matk 0.02 0.02 6.2e-04 0.03 0.02 0.02 0.02 3.9e-04 1.0e-03 1.2e-03 1.2e-03
18 LHb isoform ratio XM_039079841.1 0.15 0.11 7.9e-04 0.1 0.09 0.11 0.1 2.1e-03 3.3e-03 1.2e-03 2.4e-03
19 Brain gene expression Matk 0.13 0.08 4.2e-12 0.12 0.1 0.1 0.11 7.2e-11 5.8e-10 1.0e-09 2.4e-10
20 Brain alternative TSS XM_039079845.1 0.02 0.02 9.1e-03 0 0 -0 0 1.1e-01 1.6e-01 5.3e-01 1.7e-01
21 pVTA isoform ratio NM_021859.2 0.11 0.09 4.8e-04 0.09 0.08 0.08 0.08 1.5e-04 2.8e-04 2.9e-04 2.6e-04
22 PL intron excision ratio chr7_8461466_8465664 0.03 0.02 2.0e-03 0.02 0.02 0.01 0.02 3.4e-03 4.7e-03 1.0e-02 4.1e-03
23 PL alternative TSS XM_039079845.1 0.06 0.04 1.2e-06 0.06 0.06 0.06 0.05 2.2e-07 7.0e-07 3.6e-07 1.4e-06
24 PL isoform ratio XM_039079841.1 0.04 0.03 3.5e-06 0.05 0.05 0.05 0.05 1.4e-06 2.7e-06 4.5e-06 2.1e-06
25 PL alternative TSS XM_039079842.1 0.05 0.04 7.7e-05 0.03 0.04 0.04 0.04 1.1e-04 2.2e-05 2.8e-05 3.9e-05
26 Adipose gene expression Matk 0.03 0.03 4.9e-03 0.02 0.02 0.02 0.02 4.0e-03 2.8e-03 2.7e-03 4.7e-03
27 PL alternative TSS XM_039079842.1 0.04 0.03 5.6e-04 0.03 0.03 0.03 0.03 3.8e-04 2.1e-04 1.3e-04 4.5e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27
Bone: apparent density0.40.74.5-0.0-1.2-1.20.20.1-0.10.40.40.60.6-0.60.50.5-0.5-0.50.5-0.5-0.60.6-0.60.60.6-0.6-0.6-1.71.92.1
Area under the delay curve2.32.43.1-1.21.21.2-1.5-1.5-1.61.61.61.61.6-1.61.61.6-1.6-1.61.6-1.6-1.61.6-1.61.81.8-1.6-1.6-1.61.51.3
BMI with tail6.220.229.9-5.54.64.6-4.8-4.8-4.74.64.64.64.6-4.64.64.6-4.6-4.64.6-4.6-4.64.5-4.54.54.5-4.6-4.6-3.53.32.6
BMI without tail2.04.212.2-3.52.42.4-2.3-2.3-2.22.12.12.02.0-2.02.02.0-2.0-2.02.0-2.0-2.02.0-2.01.91.9-2.0-2.0-1.11.10.4
Body weight1.14.65.5-2.12.32.3-2.3-2.3-2.32.22.22.22.2-2.22.22.2-2.2-2.22.2-2.2-2.22.2-2.22.02.0-2.1-2.1-1.61.51.2
Weight adjusted by age0.20.32.7-1.61.00.9-0.6-0.6-0.50.40.40.30.3-0.30.40.4-0.4-0.40.4-0.4-0.40.3-0.30.20.2-0.3-0.30.2-0.1-0.4
Bone surface0.61.17.80.5-2.2-2.20.90.70.4-0.1-0.00.30.3-0.30.30.3-0.3-0.30.3-0.3-0.30.3-0.30.30.3-0.3-0.3-2.02.32.8
Bone volume0.71.18.00.6-2.2-2.20.90.70.4-0.1-0.00.30.3-0.30.30.3-0.3-0.30.3-0.3-0.30.3-0.30.30.3-0.3-0.3-2.02.22.8
Breakpoint value in progressive ratio session5.76.27.22.0-2.0-2.02.52.52.6-2.6-2.6-2.7-2.72.6-2.5-2.52.52.5-2.52.52.5-2.72.7-2.6-2.62.62.62.5-2.3-2.3
Number of licking bursts0.10.10.7-0.10.80.8-0.3-0.2-0.1-0.0-0.0-0.0-0.00.00.00.0-0.0-0.00.0-0.0-0.0-0.20.2-0.2-0.20.00.00.7-0.8-0.7
Context. condit. distance diff. score0.30.40.5-0.60.70.7-0.6-0.6-0.60.60.60.60.6-0.60.70.7-0.7-0.70.7-0.7-0.70.6-0.60.60.6-0.6-0.6-0.40.30.3
Locomotion velocity, session 10.40.41.80.7-1.3-1.30.90.80.7-0.6-0.6-0.6-0.60.6-0.6-0.60.60.6-0.60.60.6-0.40.4-0.4-0.40.60.6-0.20.30.2
Locomotion distance, session 10.20.21.20.1-1.0-1.00.40.30.2-0.0-0.00.10.1-0.10.00.0-0.0-0.00.0-0.0-0.00.2-0.20.20.2-0.1-0.1-0.91.01.1
Locomotion velocity, session 22.52.97.11.8-2.7-2.72.22.11.9-1.8-1.7-1.6-1.61.6-1.7-1.71.71.7-1.71.71.7-1.51.5-1.5-1.51.61.60.4-0.2-0.1
Locomotion distance, session 20.91.34.61.2-2.1-2.11.61.51.3-1.1-1.1-0.9-0.90.9-1.0-1.01.01.0-1.01.01.0-0.90.9-0.9-0.90.90.9-0.10.30.6
Locomotion velocity, session 36.17.17.72.7-2.5-2.52.72.82.8-2.8-2.8-2.8-2.82.8-2.8-2.82.82.8-2.82.82.8-2.72.7-2.7-2.72.82.82.3-2.1-2.0
Locomotion distance, session 30.00.00.30.0-0.0-0.00.00.00.1-0.1-0.1-0.2-0.20.2-0.2-0.20.20.2-0.20.20.2-0.00.0-0.0-0.00.20.20.2-0.2-0.5
Stereotopy head waving bouts, day 34.14.96.32.3-2.5-2.52.52.42.4-2.3-2.3-2.2-2.22.2-2.2-2.22.22.2-2.22.22.2-2.22.2-2.2-2.22.22.21.5-1.3-1.2
Stereotopy head waving duration, day 35.06.07.22.5-2.6-2.62.72.72.6-2.6-2.6-2.5-2.52.5-2.5-2.52.52.5-2.52.52.5-2.52.5-2.5-2.52.52.51.8-1.6-1.4
Locomotion velocity, session 70.60.71.20.9-1.1-1.11.01.00.9-0.9-0.9-0.8-0.80.8-0.9-0.90.90.9-0.90.90.9-0.80.8-0.8-0.80.80.80.5-0.4-0.2
Locomotion distance, session 70.00.10.4-0.20.50.5-0.3-0.3-0.20.10.10.00.0-0.00.00.0-0.0-0.00.0-0.0-0.00.1-0.10.10.1-0.0-0.00.3-0.4-0.7
Stereotopy head waving bouts, day 70.10.21.0-0.0-0.5-0.50.10.1-0.00.20.20.20.2-0.30.30.3-0.3-0.30.3-0.3-0.30.3-0.30.30.3-0.2-0.2-0.80.91.0
Stereotopy head waving duration, day 70.10.21.00.4-0.9-0.90.60.50.4-0.2-0.2-0.1-0.10.0-0.0-0.00.00.0-0.00.00.0-0.10.1-0.1-0.10.10.1-0.60.71.0
Locomotion velocity, session 80.30.31.90.5-1.4-1.40.90.80.6-0.4-0.4-0.3-0.30.3-0.2-0.20.20.2-0.20.20.2-0.30.3-0.3-0.30.30.3-0.60.81.0
Locomotion distance, session 80.00.10.30.3-0.6-0.60.40.30.3-0.2-0.2-0.1-0.10.1-0.2-0.20.20.2-0.20.20.2-0.20.2-0.2-0.20.10.1-0.10.20.3
Degree of sensitization distance0.40.40.5-0.60.60.6-0.6-0.6-0.60.60.60.70.7-0.70.70.7-0.7-0.70.7-0.7-0.70.6-0.60.60.6-0.7-0.7-0.50.50.6
Degree of sensitization stereotypy2.22.53.3-1.40.90.9-1.3-1.4-1.51.51.61.61.6-1.61.61.6-1.6-1.61.6-1.6-1.61.6-1.61.61.6-1.6-1.6-1.81.81.7
Conditioned locomotion1.21.43.9-1.52.02.0-1.6-1.5-1.41.21.21.11.1-1.11.11.1-1.1-1.11.1-1.1-1.11.1-1.11.01.0-1.1-1.1-0.20.0-0.0
Cocaine response after cond. corrected4.14.68.6-2.52.92.9-2.6-2.5-2.42.22.22.12.1-2.12.12.1-2.1-2.12.1-2.1-2.12.0-2.02.12.1-2.1-2.1-1.00.70.4
Cocaine response after cond. not corrected4.34.89.3-2.63.13.1-2.7-2.6-2.42.32.32.12.1-2.12.12.1-2.1-2.12.1-2.1-2.12.1-2.12.12.1-2.2-2.2-1.00.70.4
Cocaine response before conditioning0.40.50.90.6-1.0-1.00.80.80.8-0.7-0.7-0.7-0.70.7-0.7-0.70.70.7-0.70.70.7-0.60.6-0.7-0.70.70.70.3-0.2-0.1
Saline control response0.00.00.2-0.30.40.4-0.3-0.3-0.20.20.20.20.2-0.20.10.1-0.1-0.10.1-0.1-0.10.2-0.20.10.1-0.2-0.20.1-0.1-0.2
Bone: connectivity density0.60.93.6-0.5-0.5-0.5-0.3-0.4-0.50.70.70.90.9-0.90.80.8-0.8-0.80.8-0.8-0.81.0-1.01.01.0-0.9-0.9-1.71.81.9
Bone: cortical apparent density1.01.41.9-1.01.31.3-1.1-1.1-1.11.11.11.21.2-1.21.41.4-1.4-1.41.4-1.4-1.41.0-1.01.01.0-1.2-1.2-0.80.70.9
Bone: cortical area0.91.43.6-0.80.20.2-0.7-0.8-0.91.01.01.21.2-1.21.31.3-1.3-1.31.3-1.3-1.31.1-1.11.11.1-1.2-1.2-1.61.61.9
Bone: cortical porosity0.40.40.90.8-1.0-1.00.80.80.8-0.7-0.7-0.6-0.60.6-0.6-0.60.60.6-0.60.60.6-0.60.6-0.6-0.60.70.70.2-0.10.0
Bone: cortical porosity0.10.10.80.2-0.6-0.60.20.20.10.00.00.10.1-0.10.20.2-0.2-0.20.2-0.2-0.20.1-0.10.10.1-0.1-0.1-0.60.70.9
Bone: cortical thickness1.42.22.8-1.31.01.0-1.3-1.3-1.41.51.51.61.6-1.61.61.6-1.6-1.61.6-1.6-1.61.5-1.51.51.5-1.6-1.6-1.61.51.7
Bone: cortical thickness0.10.10.50.00.30.3-0.00.00.1-0.2-0.2-0.2-0.20.2-0.3-0.30.30.3-0.30.30.3-0.30.3-0.3-0.30.20.20.6-0.6-0.7
Bone: cortical tissue density0.71.01.4-0.91.11.1-1.0-0.9-0.90.90.90.90.9-1.01.21.2-1.2-1.21.2-1.2-1.20.8-0.80.80.8-1.0-1.0-0.60.50.8
Condit. Reinf. active minus inactive responses3.94.45.02.1-2.2-2.22.22.22.2-2.2-2.2-2.1-2.12.1-2.2-2.22.22.2-2.22.22.2-2.12.1-2.1-2.12.12.11.7-1.5-1.5
Condit. Reinf. active-inactive response ratio2.42.62.81.6-1.2-1.21.51.51.6-1.6-1.6-1.7-1.71.7-1.7-1.71.71.7-1.71.71.7-1.61.6-1.6-1.61.71.71.6-1.6-1.6
Condit. Reinf. active responses2.93.65.82.0-2.4-2.42.22.22.1-2.0-2.0-1.9-1.91.9-1.9-1.91.91.9-1.91.91.9-1.91.9-1.9-1.91.91.91.1-0.9-0.8
Condit. Reinf. inactive responses0.50.62.10.8-1.5-1.51.11.00.9-0.8-0.8-0.6-0.60.6-0.7-0.70.70.7-0.70.70.7-0.60.6-0.6-0.60.60.6-0.10.20.4
Incentive salience index mean1.72.13.71.5-1.9-1.91.71.71.6-1.5-1.5-1.4-1.41.4-1.4-1.41.41.4-1.41.41.4-1.41.4-1.4-1.41.41.40.8-0.6-0.6
Condit. Reinf. lever presses0.20.31.5-0.0-0.9-0.90.30.20.10.10.10.30.3-0.30.30.3-0.3-0.30.3-0.3-0.30.4-0.40.40.4-0.3-0.3-1.11.21.1
Condit. Reinf. active minus inactive responses2.83.54.11.9-1.2-1.21.71.71.8-1.9-1.9-1.9-1.91.9-1.9-1.91.91.9-1.91.91.9-1.91.9-1.9-1.91.91.92.0-2.0-1.9
Condit. Reinf. active-inactive response ratio0.50.52.30.50.40.40.10.20.4-0.5-0.5-0.7-0.70.7-0.7-0.70.70.7-0.70.70.7-0.70.7-0.6-0.60.70.71.3-1.4-1.5
Condit. Reinf. active responses2.43.33.71.9-1.7-1.71.81.91.9-1.9-1.9-1.8-1.81.8-1.9-1.91.91.9-1.91.91.9-1.91.9-1.8-1.81.81.81.6-1.5-1.3
Condit. Reinf. inactive responses1.01.32.51.2-1.6-1.61.41.31.3-1.2-1.2-1.0-1.01.1-1.1-1.11.11.1-1.11.11.1-1.11.1-1.1-1.11.01.00.6-0.4-0.2
Condit. Reinf. lever presses2.73.74.11.9-1.5-1.51.81.81.9-1.9-1.9-2.0-2.02.0-2.0-2.02.02.0-2.02.02.0-2.02.0-2.0-2.02.02.02.0-1.9-1.9
Condit. Reinf. lever reinforcers received2.02.83.11.6-1.4-1.41.61.61.7-1.7-1.7-1.7-1.71.7-1.8-1.81.81.8-1.81.81.7-1.71.7-1.7-1.71.71.71.6-1.5-1.4
Conditioned reinforcement - actives2.52.53.00.9-1.7-1.71.71.71.7-1.7-1.7-1.7-1.71.7-1.6-1.61.61.6-1.61.61.6-1.71.7-1.7-1.71.61.61.3-1.1-0.8
Conditioned reinforcement - inactives0.40.51.90.41.41.4-0.9-0.9-0.80.70.70.60.6-0.60.60.6-0.6-0.60.6-0.6-0.60.6-0.60.50.5-0.6-0.6-0.0-0.20.1
Conditioned locomotion8.19.810.73.2-3.0-3.03.23.33.3-3.3-3.3-3.2-3.23.2-3.2-3.23.23.2-3.23.23.2-3.23.2-3.1-3.13.23.22.7-2.5-2.3
Patch foraging indifference point 0 sec0.20.30.70.20.40.4-0.5-0.5-0.50.50.50.60.6-0.60.60.6-0.6-0.60.6-0.6-0.50.5-0.50.40.4-0.6-0.6-0.60.50.8
Patch foraging indifference point AUC1.11.21.40.2-1.0-1.01.11.11.2-1.2-1.2-1.2-1.21.2-1.1-1.11.11.1-1.11.11.1-1.21.2-1.1-1.11.21.21.1-0.9-1.1
Delay disc. indifference point, 0s delay8.39.111.7-2.92.02.0-2.7-2.8-2.93.13.13.13.1-3.13.13.1-3.1-3.13.1-3.1-3.13.2-3.23.13.1-3.0-3.0-3.43.33.0
Delay disc. indifference point, 16s delay0.20.20.3-0.10.30.3-0.4-0.4-0.40.40.40.40.4-0.40.40.4-0.4-0.40.4-0.4-0.40.4-0.40.50.5-0.5-0.5-0.40.40.4
Delay disc. indifference point, 2s delay6.26.97.9-2.82.02.0-2.5-2.5-2.62.72.72.72.7-2.72.72.7-2.7-2.72.7-2.7-2.72.8-2.82.72.7-2.7-2.7-2.72.62.3
Delay disc. indifference point, 24s delay0.50.51.3-1.10.60.6-0.7-0.8-0.70.70.70.70.7-0.70.70.7-0.7-0.70.7-0.7-0.70.7-0.70.90.9-0.8-0.8-0.60.50.3
Delay disc. indifference point, 4s delay1.41.52.6-1.00.50.5-1.0-1.0-1.11.21.21.31.3-1.31.21.2-1.2-1.21.2-1.2-1.21.2-1.21.41.4-1.3-1.3-1.61.61.5
Delay disc. indifference point, 8s delay0.80.91.5-0.41.21.2-1.1-1.1-1.11.01.01.01.0-1.00.90.9-0.9-0.90.9-0.9-0.91.0-1.01.11.1-0.9-0.9-0.60.50.1
Indifference point function ln k0.20.30.50.20.70.7-0.6-0.6-0.60.60.60.60.6-0.60.60.6-0.6-0.60.6-0.6-0.60.6-0.60.60.6-0.6-0.6-0.40.30.5
Indifference point function log k0.20.30.50.20.70.7-0.6-0.6-0.60.60.60.60.6-0.60.60.6-0.6-0.60.6-0.6-0.60.6-0.60.60.6-0.6-0.6-0.40.30.5
Patch foraging total patch changes 0 sec0.10.20.40.30.50.5-0.4-0.4-0.50.50.50.50.5-0.50.50.5-0.5-0.50.5-0.5-0.50.4-0.40.30.3-0.5-0.5-0.40.30.7
Patch foraging total patch changes 12 sec0.20.31.2-1.10.90.9-0.7-0.6-0.60.50.50.50.5-0.50.40.4-0.4-0.40.4-0.4-0.40.4-0.40.30.3-0.5-0.50.1-0.2-0.3
Patch foraging total patch changes 18 sec1.01.31.70.8-1.1-1.11.21.21.2-1.2-1.2-1.2-1.21.2-1.1-1.11.11.1-1.11.11.1-1.21.2-1.3-1.31.21.21.0-1.0-0.8
Patch foraging total patch changes 24 sec0.10.10.3-0.5-0.5-0.50.30.30.3-0.3-0.3-0.2-0.20.3-0.4-0.40.40.4-0.40.40.3-0.30.3-0.4-0.40.20.20.1-0.0-0.1
Patch foraging total patch changes 6 sec0.20.32.01.4-0.4-0.40.50.50.5-0.5-0.5-0.4-0.40.4-0.4-0.40.40.4-0.40.40.5-0.60.6-0.6-0.60.40.40.4-0.50.0
Patch foraging time to switch 0 sec1.93.05.0-1.11.01.0-1.5-1.5-1.71.71.81.91.9-1.81.71.7-1.7-1.71.7-1.7-1.71.8-1.81.71.7-1.9-1.9-2.12.02.2
Patch foraging water rate 0 sec0.20.41.80.10.50.50.10.20.3-0.4-0.4-0.5-0.50.5-0.5-0.50.50.5-0.50.50.5-0.60.6-0.4-0.40.50.51.2-1.3-1.3
Patch foraging water rate 12 sec0.61.03.1-1.61.81.8-1.3-1.2-1.10.90.90.80.8-0.80.90.9-0.9-0.90.9-0.9-0.90.8-0.80.80.8-0.8-0.80.1-0.2-0.6
Patch foraging water rate 18 sec0.81.05.40.10.80.80.10.20.5-0.7-0.7-0.8-0.80.8-0.8-0.80.80.8-0.80.80.9-1.01.0-0.8-0.80.80.82.0-2.1-2.3
Patch foraging water rate 24 sec0.50.63.50.31.91.9-0.8-0.7-0.50.20.2-0.1-0.10.1-0.1-0.10.10.1-0.10.10.1-0.10.10.10.10.10.11.4-1.7-1.9
Patch foraging water rate 6 sec0.91.33.90.80.00.00.50.60.8-0.9-1.0-1.1-1.11.1-1.2-1.21.21.2-1.21.21.2-1.11.1-1.0-1.01.11.11.7-1.8-2.0
Seeking ratio, delayed vs. immediate footshock4.55.27.22.7-2.7-2.62.52.52.4-2.4-2.4-2.3-2.32.3-2.3-2.32.32.3-2.32.32.3-2.22.2-2.2-2.22.32.31.5-1.3-1.2
Distance traveled before self-admin0.30.30.5-0.50.30.3-0.5-0.5-0.50.60.60.60.6-0.60.60.6-0.6-0.60.6-0.6-0.50.6-0.60.70.7-0.5-0.5-0.70.60.4
Distance traveled after self-admin0.91.01.51.2-1.2-1.21.11.01.0-1.0-1.0-0.9-0.90.9-1.0-1.01.01.0-1.01.01.0-0.90.9-0.9-0.91.01.00.6-0.6-0.7
Extensor digitorum longus weight3.915.321.5-4.14.64.6-4.5-4.4-4.34.14.13.93.9-3.94.04.0-4.0-4.04.0-4.0-4.03.9-4.04.14.1-3.9-3.9-2.52.11.4
Bone: elastic displacement0.30.30.40.6-0.6-0.60.60.60.6-0.6-0.6-0.6-0.60.6-0.6-0.60.60.6-0.60.60.6-0.50.5-0.5-0.50.60.60.4-0.3-0.4
Bone: elastic work0.30.30.8-0.40.20.2-0.4-0.4-0.50.50.50.60.6-0.60.60.6-0.6-0.60.6-0.6-0.60.6-0.60.60.6-0.6-0.6-0.80.80.9
Bone: endosteal estimation0.30.71.2-0.60.30.3-0.6-0.6-0.70.70.70.80.8-0.80.90.9-0.9-0.90.9-0.9-0.90.8-0.80.80.8-0.8-0.8-1.01.01.1
Bone: endosteal perimeter0.10.31.30.7-1.1-1.10.80.80.7-0.5-0.5-0.4-0.40.4-0.3-0.30.30.3-0.30.30.3-0.40.4-0.4-0.40.40.4-0.30.40.6
Epididymis fat weight0.20.61.30.4-0.3-0.30.50.60.6-0.7-0.7-0.8-0.80.8-0.8-0.80.80.8-0.80.80.8-0.80.8-0.7-0.70.80.81.0-1.0-1.1
Delta time in closed arm before/after self-admin0.40.42.2-0.91.51.5-0.9-0.8-0.60.40.40.30.3-0.30.20.2-0.2-0.20.2-0.2-0.20.3-0.30.20.2-0.2-0.20.7-0.9-1.0
Delta time in open arm before/after self-admin1.41.41.6-0.51.01.0-1.1-1.2-1.21.21.21.21.2-1.21.31.3-1.3-1.31.3-1.3-1.21.2-1.21.31.3-1.2-1.2-1.21.01.0
Diff in mean of infusions in LGA sessions1.61.82.01.1-1.2-1.21.41.41.4-1.4-1.4-1.4-1.41.4-1.3-1.31.31.3-1.31.31.4-1.41.4-1.3-1.31.41.41.2-1.1-1.1
Delay discount exponential model param2.02.12.81.2-1.2-1.21.41.51.5-1.5-1.5-1.5-1.51.5-1.5-1.51.51.5-1.51.51.5-1.51.5-1.7-1.71.51.51.5-1.4-1.1
Extinction: sum of active levers before priming1.81.73.00.9-0.5-0.51.01.11.2-1.3-1.3-1.4-1.41.4-1.3-1.31.31.3-1.31.31.3-1.41.4-1.5-1.51.41.41.7-1.7-1.6
Active lever presses in extinction session 63.02.93.51.3-1.8-1.81.91.91.8-1.8-1.8-1.8-1.81.8-1.7-1.71.71.7-1.71.71.7-1.81.8-1.8-1.81.71.71.4-1.2-1.2
Bone: final force1.62.54.1-1.40.70.7-1.2-1.3-1.41.51.51.71.7-1.71.71.7-1.7-1.71.7-1.7-1.71.6-1.61.61.6-1.7-1.7-1.91.92.0
Bone: final moment1.32.13.5-1.20.60.6-1.1-1.2-1.31.41.41.51.5-1.51.51.5-1.5-1.51.5-1.5-1.51.4-1.41.41.4-1.5-1.5-1.81.71.9
Food consumed during 24 hour testing period0.50.50.6-0.80.80.8-0.8-0.8-0.80.80.80.80.8-0.80.80.8-0.8-0.80.8-0.8-0.80.7-0.70.70.7-0.8-0.8-0.60.50.5
Glucose1.11.62.0-1.31.41.4-1.4-1.4-1.41.41.31.31.3-1.31.21.2-1.2-1.21.2-1.2-1.21.4-1.41.41.4-1.3-1.3-1.00.90.5
Heart weight0.50.71.40.3-0.4-0.40.60.70.7-0.8-0.8-0.9-0.90.9-0.9-0.90.90.9-0.90.90.9-0.80.8-0.8-0.80.90.91.1-1.0-1.2
Delay discount hyperbolic model param2.93.13.81.6-1.4-1.41.71.81.8-1.8-1.8-1.8-1.81.8-1.8-1.81.81.8-1.81.81.8-1.81.8-1.9-1.91.81.81.8-1.7-1.4
Intermittent access intake day 1-15 change7.57.410.53.2-2.2-2.22.72.72.7-2.8-2.8-2.8-2.82.8-2.8-2.82.82.8-2.82.82.8-2.82.8-2.8-2.82.82.82.6-2.5-2.0
Intermittent access intake escalation8.07.910.53.2-1.7-1.72.52.62.7-2.8-2.8-3.0-3.02.9-2.9-2.92.92.9-2.92.92.9-2.92.9-2.9-2.92.92.93.1-3.0-2.7
Intermittent access intake escalation 29.59.410.73.0-2.1-2.12.82.93.0-3.1-3.1-3.2-3.23.2-3.2-3.23.23.2-3.23.23.2-3.23.2-3.2-3.23.23.23.3-3.2-3.0
Intermitt. access day 1 inactive lever presses0.70.82.01.0-0.3-0.30.60.60.7-0.8-0.8-0.9-0.90.9-0.9-0.90.90.9-0.90.90.9-0.90.9-0.7-0.70.90.91.1-1.1-1.4
Intermitt. access day 15 inactive lever presses0.50.61.81.3-0.2-0.20.60.70.7-0.7-0.7-0.8-0.80.8-0.7-0.70.70.7-0.70.70.7-0.80.8-0.8-0.80.70.70.9-1.0-0.7
Intermitt. access escalation Index0.60.61.8-1.0-0.2-0.2-0.3-0.3-0.40.60.60.70.7-0.70.80.8-0.8-0.80.8-0.8-0.80.7-0.70.70.7-0.8-0.8-1.21.31.3
Intermittent access day 1 total infusions0.10.10.6-0.20.30.3-0.3-0.3-0.30.30.30.20.2-0.30.40.4-0.4-0.40.4-0.4-0.40.3-0.30.20.2-0.4-0.4-0.30.30.8
Intermittent access day 15 total infusions2.12.43.31.8-0.9-0.91.41.51.5-1.6-1.6-1.7-1.71.7-1.5-1.51.51.5-1.51.51.5-1.71.7-1.8-1.81.51.51.7-1.7-1.1
Intermittent access terminal intake (last 3 days)1.11.21.70.6-1.0-1.01.21.21.2-1.2-1.2-1.3-1.31.2-1.0-1.01.01.0-1.01.01.1-1.21.2-1.3-1.31.01.01.1-0.9-0.5
Intermittent access total infusions0.20.20.50.7-0.1-0.10.40.40.5-0.5-0.5-0.6-0.60.6-0.4-0.40.40.4-0.40.40.4-0.60.6-0.7-0.70.40.40.6-0.7-0.1
Intermittent access day 1 locomotion0.30.31.11.0-0.2-0.20.50.50.5-0.6-0.6-0.7-0.70.7-0.5-0.50.50.5-0.50.50.5-0.60.6-0.7-0.70.50.50.7-0.7-0.2
Intermittent access day 15 total locomotion3.84.17.22.7-1.5-1.52.02.02.0-2.1-2.1-2.2-2.22.2-2.0-2.02.02.0-2.02.02.0-2.22.2-2.1-2.12.02.02.0-2.0-1.4
Intermittent access total locomotion1.11.22.51.6-0.9-0.91.11.11.1-1.1-1.1-1.2-1.21.2-1.0-1.01.01.0-1.01.01.0-1.21.2-1.2-1.21.01.01.0-1.0-0.5
Intermittent access standard deviation3.63.84.51.7-1.5-1.51.91.92.0-2.0-2.0-2.1-2.12.1-2.0-2.02.02.0-2.02.02.0-2.12.1-2.0-2.02.02.02.0-1.9-1.7
Left kidney weight0.00.10.7-0.8-0.8-0.80.40.30.3-0.2-0.2-0.0-0.00.0-0.0-0.00.00.0-0.00.00.0-0.00.0-0.1-0.10.10.1-0.40.60.5
Right kidney weight1.33.75.21.4-2.3-2.32.22.12.1-2.0-2.0-1.9-1.91.9-2.0-2.02.02.0-2.02.02.0-2.02.0-2.0-2.02.02.01.4-1.2-1.1
Cocaine induced anxiety0.50.62.20.2-1.5-1.51.01.00.9-0.8-0.8-0.6-0.60.7-0.7-0.70.70.7-0.70.70.7-0.60.6-0.6-0.60.70.7-0.00.20.0
Post-drug Anxiety0.30.42.2-0.8-1.5-1.50.80.70.6-0.5-0.4-0.3-0.30.3-0.4-0.40.40.4-0.40.40.4-0.30.3-0.3-0.30.40.4-0.50.80.4
Baseline Anxiety0.10.10.3-0.10.20.20.10.10.2-0.2-0.2-0.2-0.20.2-0.2-0.20.20.2-0.20.20.2-0.30.3-0.3-0.30.20.20.5-0.5-0.4
Tail length3.410.212.53.5-2.6-2.63.13.23.2-3.3-3.3-3.3-3.33.3-3.3-3.33.33.3-3.33.33.3-3.23.2-3.3-3.33.33.33.0-2.9-2.7
Length with tail1.86.814.53.8-2.6-2.62.72.72.7-2.7-2.7-2.6-2.62.6-2.6-2.62.62.6-2.62.62.6-2.62.6-2.7-2.72.72.72.0-1.9-1.4
Length without tail0.10.21.91.4-0.7-0.70.40.30.2-0.1-0.1-0.0-0.00.0-0.0-0.00.00.0-0.00.00.0-0.00.0-0.1-0.10.10.1-0.60.60.9
Times rat made contact with spout0.10.10.5-0.40.70.7-0.5-0.5-0.40.30.30.30.3-0.30.20.2-0.2-0.20.2-0.2-0.20.3-0.30.30.3-0.3-0.30.2-0.2-0.3
Lifetime Intake0.10.10.2-0.1-0.1-0.10.30.30.3-0.3-0.3-0.4-0.40.3-0.1-0.10.10.1-0.10.10.1-0.30.3-0.5-0.50.10.10.3-0.30.3
Liver weight, left2.23.56.6-2.62.12.1-2.1-2.1-2.12.02.01.81.8-1.81.91.9-1.9-1.91.9-1.9-1.91.9-1.91.81.8-1.8-1.8-1.31.10.6
Liver weight, right1.72.83.2-1.71.61.6-1.7-1.8-1.81.81.81.71.7-1.71.71.7-1.7-1.71.7-1.7-1.71.8-1.81.81.8-1.7-1.7-1.51.41.1
Locomotor activity2.84.49.83.1-2.7-2.72.52.52.3-2.2-2.2-2.0-2.02.0-2.0-2.02.02.0-2.02.02.0-2.12.1-2.1-2.12.02.01.1-0.9-0.2
Locomotor testing distance1.72.85.12.3-2.0-2.02.02.01.9-1.8-1.8-1.7-1.71.6-1.6-1.61.61.6-1.61.61.6-1.71.7-1.7-1.71.61.61.0-0.9-0.3
Locomotor testing rearing0.00.10.2-0.10.00.00.20.20.2-0.3-0.3-0.3-0.30.3-0.2-0.20.20.2-0.20.20.2-0.30.3-0.3-0.30.30.30.4-0.4-0.4
Locomotion in novel chamber0.50.71.40.3-0.6-0.50.70.70.8-0.8-0.8-0.9-0.90.9-0.9-0.90.90.9-0.90.90.9-0.80.8-0.8-0.80.80.81.0-0.9-1.2
Locomotion in novel chamber post-restriction0.70.91.30.7-0.8-0.91.01.01.0-1.0-1.0-0.9-0.90.9-1.0-1.01.01.0-1.01.00.9-1.01.0-1.1-1.10.90.90.8-0.7-0.4
Fecal boli incidents, locomotor time 11.51.73.6-1.31.91.9-1.6-1.5-1.41.31.31.21.2-1.21.31.3-1.3-1.31.3-1.3-1.31.2-1.21.11.1-1.2-1.2-0.50.40.3
Change in fecal boli incidents, locomotor task0.20.21.20.2-1.1-1.10.70.60.5-0.4-0.4-0.3-0.30.3-0.3-0.30.30.3-0.30.30.3-0.30.3-0.4-0.40.40.4-0.40.50.4
Time >=10cm from walls, locomotor time 10.50.51.4-0.70.10.1-0.4-0.5-0.60.60.60.70.7-0.70.70.7-0.7-0.70.7-0.7-0.70.7-0.70.70.7-0.8-0.8-1.01.01.2
Bouts of movement, locomotor time 10.20.20.30.4-0.3-0.30.40.40.4-0.4-0.4-0.5-0.50.5-0.4-0.40.40.4-0.40.40.4-0.50.5-0.5-0.50.40.40.5-0.5-0.3
Total resting periods, locomotor time 10.20.20.30.5-0.4-0.40.50.50.5-0.5-0.5-0.5-0.50.5-0.4-0.40.40.4-0.40.40.4-0.50.5-0.5-0.50.40.40.4-0.4-0.1
Rest time, locomotor task time 10.10.10.30.0-0.5-0.50.50.50.5-0.4-0.4-0.4-0.40.4-0.3-0.30.30.3-0.30.30.3-0.40.4-0.5-0.50.40.40.2-0.3-0.0
Distance moved, locomotor task time 10.60.71.7-0.20.10.1-0.5-0.6-0.70.80.80.80.8-0.80.80.8-0.8-0.80.8-0.8-0.80.8-0.80.90.9-0.8-0.8-1.21.31.3
Vertical activity count, locomotor time 10.00.00.10.30.30.3-0.3-0.2-0.20.20.20.20.2-0.20.10.1-0.1-0.10.1-0.1-0.10.2-0.20.10.1-0.1-0.1-0.0-0.0-0.2
Time >=10cm from walls, locomotor time 20.90.91.6-1.01.31.3-1.1-1.1-1.11.01.00.90.9-0.91.01.0-1.0-1.01.0-1.0-1.00.9-0.91.01.0-1.0-1.0-0.50.20.4
Bouts of movement, locomotor time 20.30.31.10.7-1.0-1.00.70.70.6-0.5-0.5-0.4-0.40.4-0.4-0.40.40.4-0.40.40.4-0.40.4-0.3-0.30.40.4-0.20.30.4
Total resting periods, locomotor time 20.20.21.10.4-1.1-1.10.70.60.5-0.4-0.4-0.3-0.30.3-0.4-0.40.40.4-0.40.40.4-0.30.3-0.2-0.20.30.3-0.30.40.6
Rest time, locomotor task time 20.30.41.00.4-1.0-1.00.80.80.7-0.7-0.7-0.6-0.60.6-0.5-0.50.50.5-0.50.50.5-0.60.6-0.5-0.50.40.40.2-0.10.3
Distance moved, locomotor task time 20.60.61.5-0.51.21.2-1.0-1.0-0.90.90.80.80.8-0.80.80.8-0.8-0.80.8-0.8-0.80.8-0.80.80.8-0.8-0.8-0.30.10.1
Vertical activity count, locomotor time 20.50.52.0-0.61.41.4-1.0-0.9-0.80.70.70.60.6-0.60.70.7-0.7-0.70.7-0.7-0.70.6-0.60.50.5-0.5-0.50.1-0.4-0.4
Light reinforcement 15.49.814.93.9-3.2-3.23.33.33.3-3.2-3.3-3.1-3.13.1-3.2-3.23.23.2-3.23.23.2-3.13.1-3.2-3.23.13.12.5-2.2-1.8
Light reinforcement 21.72.25.62.4-1.4-1.41.61.61.6-1.5-1.5-1.5-1.51.5-1.4-1.41.41.4-1.41.41.5-1.51.5-1.5-1.51.51.51.1-1.1-0.7
Bone: marrow area0.30.71.2-0.60.30.3-0.6-0.6-0.70.80.80.80.8-0.80.90.9-0.9-0.90.9-0.9-0.90.8-0.80.80.8-0.8-0.8-1.01.01.1
Bone: maximum diameter0.40.72.51.1-1.6-1.61.31.21.0-0.9-0.9-0.7-0.70.6-0.6-0.60.60.6-0.60.60.6-0.80.8-0.8-0.80.70.7-0.10.30.7
Bone: maximum force1.62.73.8-1.40.90.9-1.3-1.4-1.51.61.61.71.7-1.71.81.8-1.8-1.81.8-1.8-1.81.6-1.61.61.6-1.7-1.7-1.81.82.0
Bone: maximum moment1.32.33.4-1.20.80.8-1.2-1.3-1.41.41.41.61.6-1.61.71.7-1.7-1.71.7-1.7-1.71.5-1.51.51.5-1.6-1.6-1.71.61.9
Mean time between licks in bursts4.26.06.52.5-2.0-2.02.42.42.5-2.5-2.5-2.5-2.52.5-2.5-2.52.52.5-2.52.52.5-2.62.6-2.6-2.62.52.52.4-2.3-2.1
Mean num. licks in bursts0.00.00.3-0.2-0.2-0.2-0.1-0.1-0.10.20.20.20.2-0.10.10.1-0.1-0.10.1-0.1-0.10.3-0.30.30.3-0.2-0.2-0.50.50.3
Cd content in liver0.20.20.3-0.40.30.3-0.4-0.5-0.50.50.50.50.5-0.50.50.5-0.5-0.50.5-0.5-0.50.5-0.50.50.5-0.5-0.5-0.50.50.5
Co content in liver0.70.81.21.1-0.6-0.60.80.80.9-0.9-0.9-0.9-0.90.9-0.9-0.90.90.9-0.90.90.9-0.90.9-0.7-0.70.90.91.0-1.0-1.0
Cu content in liver0.20.31.1-0.0-0.2-0.2-0.1-0.2-0.30.40.40.50.5-0.50.50.5-0.5-0.50.5-0.5-0.50.5-0.60.70.7-0.5-0.5-1.01.01.0
Fe content in liver0.10.10.3-0.10.20.20.00.10.1-0.2-0.2-0.2-0.20.2-0.2-0.20.20.2-0.20.20.2-0.20.3-0.3-0.30.20.20.5-0.5-0.5
K content in liver0.10.10.5-0.2-0.7-0.70.10.1-0.00.10.10.20.2-0.20.20.2-0.2-0.20.2-0.2-0.20.3-0.30.50.5-0.2-0.2-0.70.70.7
Mg content in liver0.20.20.9-0.3-0.8-0.80.20.1-0.00.10.10.20.2-0.20.20.2-0.2-0.20.2-0.2-0.20.3-0.40.60.6-0.2-0.2-0.90.90.9
Mn content in liver0.60.74.00.7-2.0-2.01.31.10.9-0.7-0.7-0.5-0.50.5-0.5-0.50.50.5-0.50.50.5-0.40.5-0.4-0.40.50.5-0.71.01.3
Na content in liver1.31.31.9-0.90.60.6-1.0-1.0-1.11.11.21.21.2-1.21.21.2-1.2-1.21.2-1.2-1.21.3-1.21.11.1-1.2-1.2-1.41.31.4
Rb content in liver0.70.92.3-0.9-0.1-0.1-0.5-0.6-0.70.80.80.90.9-0.90.90.9-0.9-0.90.9-0.9-0.90.9-0.91.01.0-0.9-0.9-1.41.51.5
Se content in liver0.10.20.30.3-0.6-0.60.50.50.5-0.4-0.4-0.4-0.40.4-0.4-0.40.40.4-0.40.40.4-0.40.4-0.3-0.30.40.40.2-0.2-0.1
Sr content in liver0.20.20.80.20.50.5-0.1-0.00.1-0.2-0.2-0.3-0.30.3-0.3-0.30.30.3-0.30.30.3-0.30.3-0.6-0.60.30.30.8-0.9-0.9
Zn content in liver2.93.27.01.3-0.8-0.81.31.41.6-1.7-1.7-1.9-1.91.9-1.9-1.91.91.9-1.91.91.9-1.91.8-1.7-1.71.91.92.4-2.4-2.6
Bone: minimum diameter0.10.21.1-0.0-0.3-0.30.0-0.0-0.10.20.20.30.3-0.40.40.4-0.4-0.40.4-0.4-0.40.3-0.30.30.3-0.3-0.3-0.80.81.0
Time in familiar zone, hab. session 12.42.22.51.4-1.2-1.21.41.41.5-1.5-1.5-1.5-1.51.5-1.6-1.61.61.6-1.61.61.6-1.61.6-1.6-1.61.51.51.4-1.3-1.2
Time in novel zone, hab. session 11.41.42.3-1.00.50.5-0.8-0.9-1.01.11.11.21.2-1.21.21.2-1.2-1.21.2-1.2-1.21.2-1.21.21.2-1.2-1.2-1.51.51.5
Total zone transitions, hab. session 10.60.82.71.0-1.6-1.61.21.11.0-0.9-0.9-0.7-0.70.7-0.8-0.80.80.8-0.80.80.8-0.70.7-0.7-0.70.70.7-0.00.20.4
Total locomotion distance, hab. session 10.70.94.41.0-2.1-2.11.41.31.1-0.9-0.8-0.6-0.60.7-0.8-0.80.80.8-0.80.80.8-0.60.6-0.6-0.60.60.6-0.60.81.0
Locomotion velocity, hab. session 11.01.44.61.2-2.1-2.11.61.51.3-1.2-1.1-1.0-1.01.0-1.1-1.11.11.1-1.11.11.1-1.01.0-1.0-1.01.01.0-0.10.30.5
Time in familiar zone, hab. session 27.17.38.02.6-2.1-2.12.52.62.7-2.7-2.7-2.8-2.82.8-2.8-2.82.82.8-2.82.82.8-2.82.8-2.8-2.82.82.82.7-2.6-2.6
Time in novel zone, hab. session 25.45.46.3-2.21.61.6-2.1-2.1-2.22.32.32.42.4-2.42.42.4-2.4-2.42.4-2.4-2.42.4-2.42.42.4-2.4-2.4-2.52.42.4
Total zone transitions, hab. session 20.60.73.1-0.6-0.4-0.4-0.3-0.4-0.50.70.70.90.9-0.80.70.7-0.7-0.70.7-0.7-0.70.8-0.80.80.8-0.9-0.9-1.51.61.8
Total locomotion distance, hab. session 20.60.72.50.9-1.6-1.61.11.11.0-0.8-0.8-0.7-0.70.7-0.9-0.90.90.9-0.90.90.9-0.70.7-0.7-0.70.70.7-0.00.20.4
Locomotion velocity, hab. session 20.50.72.80.8-1.7-1.71.11.00.9-0.7-0.7-0.6-0.60.6-0.7-0.70.70.7-0.70.70.7-0.60.6-0.6-0.60.60.6-0.30.50.7
Novel to familiar place preference ratio4.74.96.5-2.11.31.3-1.9-2.0-2.12.22.22.22.2-2.32.32.3-2.3-2.32.3-2.3-2.32.3-2.32.32.3-2.2-2.2-2.52.52.3
Novelty place preference2.92.94.4-1.60.90.9-1.4-1.5-1.61.71.71.71.7-1.71.81.8-1.8-1.81.8-1.8-1.81.9-1.91.91.9-1.7-1.7-2.12.11.8
Time in novel zone, NPP test3.23.34.6-1.81.01.0-1.5-1.6-1.71.81.81.81.8-1.81.91.9-1.9-1.91.9-1.9-1.92.0-2.02.02.0-1.8-1.8-2.12.11.8
Total zone transitions, NPP test0.10.10.8-0.2-0.3-0.3-0.0-0.1-0.20.20.20.40.4-0.30.20.2-0.2-0.20.2-0.2-0.20.3-0.30.30.3-0.4-0.4-0.70.70.9
Total locomotion distance, NPP test0.20.31.4-0.3-0.5-0.5-0.0-0.1-0.20.30.40.50.5-0.40.30.3-0.3-0.30.3-0.3-0.30.5-0.50.50.5-0.5-0.5-1.01.11.2
Locomotion velocity, NPP test0.10.10.80.0-0.7-0.70.30.20.10.00.00.20.2-0.10.00.0-0.0-0.00.0-0.0-0.00.2-0.20.20.2-0.2-0.2-0.70.80.9
Intraocular pressure0.20.32.2-0.70.40.4-0.00.10.2-0.4-0.4-0.5-0.50.5-0.5-0.50.50.5-0.50.50.5-0.50.5-0.5-0.50.50.51.1-1.1-1.5
Delta distance traveled before/after self-admin1.51.72.71.6-1.3-1.31.31.31.3-1.3-1.3-1.3-1.31.3-1.3-1.31.31.3-1.31.31.3-1.31.3-1.4-1.41.31.31.0-0.9-0.7
Delta ambulatory time before/after self-admin1.51.62.61.0-1.6-1.61.51.41.4-1.4-1.3-1.3-1.31.3-1.3-1.31.31.3-1.31.31.3-1.31.3-1.4-1.41.21.20.8-0.7-0.5
Parametrial fat weight0.51.02.41.5-0.6-0.60.91.01.0-1.0-1.0-1.1-1.11.1-1.0-1.01.01.0-1.01.01.0-1.01.0-1.0-1.01.11.11.0-1.0-0.9
Pavlov. Cond. lever latency0.20.21.00.20.50.5-0.10.00.1-0.2-0.2-0.3-0.30.3-0.3-0.30.30.3-0.30.30.3-0.40.4-0.4-0.40.30.30.9-1.0-1.0
Pavlov. Cond. magazine entry latency2.83.64.11.9-1.7-1.71.91.92.0-2.0-2.0-1.9-1.91.9-1.9-1.91.91.9-1.91.91.9-2.02.0-2.0-2.01.91.91.8-1.7-1.4
Pavlov. Cond. change in total contacts0.00.10.10.2-0.3-0.30.30.20.2-0.2-0.2-0.2-0.20.2-0.3-0.30.30.3-0.30.30.3-0.20.2-0.2-0.20.20.20.1-0.1-0.1
Pavlov. Cond. index score0.20.30.90.6-1.0-1.00.80.70.6-0.6-0.6-0.5-0.50.5-0.5-0.50.50.5-0.50.50.5-0.50.5-0.5-0.50.50.50.00.10.2
Pavlov. Cond. latency score0.20.31.20.5-1.1-1.10.80.70.6-0.5-0.5-0.4-0.40.4-0.4-0.40.40.4-0.40.40.4-0.40.4-0.4-0.40.40.4-0.20.40.5
Pavlov. Cond. lever contacts0.10.21.00.0-0.8-0.80.30.20.10.00.00.10.1-0.10.10.1-0.1-0.10.1-0.1-0.10.2-0.20.20.2-0.1-0.1-0.91.01.0
Pavlov. Cond. magazine entry number0.60.70.8-0.80.80.8-0.9-0.9-0.90.90.90.80.8-0.80.80.8-0.8-0.80.8-0.8-0.80.9-0.90.90.9-0.8-0.8-0.70.60.5
Pavlov. Cond. intertrial magazine entries0.20.30.90.30.10.10.20.30.4-0.4-0.4-0.4-0.40.5-0.5-0.50.50.5-0.50.50.5-0.60.6-0.6-0.60.40.40.9-1.0-0.9
Pavlov. Cond. lever-magazine prob. diff.0.50.71.40.8-1.2-1.21.01.00.9-0.9-0.8-0.8-0.80.8-0.8-0.80.80.8-0.80.80.8-0.80.8-0.8-0.80.80.80.3-0.2-0.1
Pavlov. Cond. response bias1.01.21.41.0-1.1-1.11.21.21.1-1.1-1.1-1.1-1.11.1-1.1-1.11.11.1-1.11.11.1-1.11.1-1.1-1.11.11.10.8-0.7-0.7
Pavlov. Cond. lever latency0.91.21.4-1.11.21.2-1.2-1.2-1.11.11.11.11.1-1.11.11.1-1.1-1.11.1-1.1-1.11.0-1.01.11.1-1.1-1.1-0.80.70.6
Pavlov. Cond. magazine entry latency0.40.50.90.8-0.9-0.90.90.80.8-0.8-0.8-0.8-0.80.7-0.6-0.60.60.6-0.60.60.7-0.70.7-0.7-0.70.80.80.4-0.3-0.4
Pavlov. Cond. change in total contacts1.01.41.51.2-1.1-1.11.11.11.2-1.2-1.2-1.2-1.21.2-1.2-1.21.21.2-1.21.21.2-1.11.1-1.1-1.11.21.21.0-0.9-1.0
Pavlov. Cond. index score1.01.31.51.2-1.2-1.21.21.21.2-1.2-1.2-1.2-1.21.2-1.1-1.11.11.1-1.11.11.2-1.11.1-1.1-1.11.21.20.9-0.8-0.8
Pavlov. Cond. latency score0.81.01.41.1-1.2-1.21.21.11.1-1.1-1.1-1.1-1.11.1-1.0-1.01.01.0-1.01.01.0-1.01.0-1.0-1.01.11.10.7-0.6-0.6
Pavlov. Cond. lever contacts0.91.21.41.1-1.0-1.01.11.11.1-1.1-1.1-1.2-1.21.2-1.2-1.21.21.2-1.21.21.2-1.11.1-1.1-1.11.21.21.0-1.0-1.0
Pavlov. Cond. magazine entry number0.81.01.5-1.21.21.2-1.1-1.1-1.11.01.01.01.0-1.00.90.9-0.9-0.90.9-0.9-0.91.0-1.00.90.9-1.0-1.0-0.50.40.6
Pavlov. Cond. intertrial magazine entries0.30.41.2-0.71.11.1-0.8-0.7-0.70.60.60.70.7-0.70.60.6-0.6-0.60.6-0.6-0.60.4-0.40.40.4-0.7-0.70.0-0.10.2
Pavlov. Cond. lever-magazine prob. diff.0.91.21.51.2-1.2-1.21.21.21.2-1.1-1.1-1.2-1.21.1-1.1-1.11.11.1-1.11.11.1-1.11.1-1.1-1.11.21.20.8-0.7-0.7
Pavlov. Cond. response bias2.12.93.21.7-1.5-1.51.71.71.7-1.7-1.7-1.8-1.81.8-1.7-1.71.71.7-1.71.71.7-1.71.7-1.7-1.71.81.81.5-1.4-1.5
Time in closed arm before self-admin1.21.42.8-0.50.40.4-0.9-0.9-1.01.11.11.21.2-1.21.21.2-1.2-1.21.2-1.2-1.21.2-1.21.21.2-1.3-1.3-1.51.61.7
Time in closed arm after self-admin0.00.00.1-0.3-0.2-0.20.10.10.1-0.1-0.1-0.0-0.00.1-0.3-0.30.30.3-0.30.30.2-0.00.0-0.2-0.20.20.20.1-0.1-0.2
Time in open arm before self-admin1.31.41.61.1-0.9-0.91.11.11.2-1.2-1.2-1.2-1.21.2-1.3-1.31.31.3-1.31.31.3-1.21.2-1.1-1.11.21.21.2-1.2-1.2
Time in open arm after self-admin0.60.71.30.01.11.1-0.9-0.9-0.90.90.90.80.8-0.80.90.9-0.9-0.90.9-0.9-0.90.7-0.71.01.0-0.8-0.8-0.50.40.3
Bone: periosteal estimation0.61.33.9-0.70.10.1-0.6-0.7-0.81.01.01.21.2-1.21.31.3-1.3-1.31.3-1.3-1.31.1-1.11.11.1-1.2-1.2-1.71.72.0
Bone: periosteal perimeter0.10.21.50.3-0.9-0.90.40.40.2-0.1-0.10.10.1-0.10.20.2-0.2-0.20.2-0.2-0.20.0-0.00.00.0-0.1-0.1-0.80.91.2
Bone: post-yield work0.70.91.1-0.91.01.0-0.9-0.9-0.90.90.91.01.0-1.01.11.1-1.1-1.11.1-1.1-1.10.8-0.80.80.8-1.0-1.0-0.70.60.8
Progressive ratio test 1 active lever presses0.10.10.4-0.40.70.7-0.4-0.4-0.30.30.30.20.2-0.20.30.3-0.3-0.30.3-0.3-0.30.2-0.20.10.1-0.3-0.30.0-0.10.2
Progressive ratio test 1 breakpoint0.20.20.5-0.70.70.7-0.5-0.5-0.40.40.40.30.3-0.30.50.5-0.5-0.50.5-0.5-0.50.3-0.30.20.2-0.5-0.5-0.10.10.3
Progressive ratio test 1 inactive lever presses0.00.00.10.3-0.0-0.00.10.10.1-0.1-0.1-0.1-0.10.1-0.0-0.00.00.0-0.00.00.0-0.10.1-0.1-0.10.00.00.0-0.10.2
Progressive ratio test 2 active lever presses0.30.30.70.1-0.2-0.20.50.50.5-0.6-0.6-0.7-0.70.7-0.6-0.60.60.6-0.60.60.6-0.70.7-0.7-0.70.60.60.8-0.8-0.6
Progressive ratio test 2 breakpoint0.30.30.50.0-0.6-0.60.60.60.6-0.7-0.6-0.7-0.70.7-0.6-0.60.60.6-0.60.60.6-0.70.7-0.7-0.70.60.60.6-0.5-0.4
Progressive ratio test 2 inactive lever presses0.00.00.10.1-0.2-0.20.30.30.3-0.3-0.2-0.3-0.30.2-0.1-0.10.10.1-0.10.10.2-0.20.2-0.3-0.30.10.10.1-0.10.2
Incentive Sensitization - Responses0.50.51.0-0.1-0.4-0.40.60.60.7-0.7-0.7-0.8-0.80.8-0.7-0.70.70.7-0.70.70.7-0.80.8-0.7-0.70.70.70.9-0.8-1.0
Incentive Sensitization - Breakpoint0.50.50.9-0.3-0.6-0.60.70.70.7-0.7-0.7-0.8-0.80.8-0.8-0.80.80.8-0.80.80.8-0.80.8-0.7-0.70.80.80.8-0.7-0.9
Sum of active levers in priming session hrs 5-60.00.00.10.00.20.2-0.0-0.00.0-0.0-0.0-0.1-0.10.00.00.0-0.0-0.00.0-0.0-0.0-0.10.1-0.0-0.00.00.00.2-0.2-0.3
Progressive ratio0.20.21.4-1.20.50.5-0.5-0.5-0.40.40.40.20.2-0.20.30.3-0.3-0.30.3-0.3-0.30.4-0.40.40.4-0.2-0.20.00.0-0.7
Food seeking constrained by brief footshock0.10.10.3-0.3-0.5-0.50.30.30.3-0.3-0.3-0.2-0.20.3-0.5-0.50.50.5-0.50.50.4-0.30.3-0.4-0.40.20.20.2-0.20.0
Seeking ratio, punishment vs. effort0.10.10.90.9-0.3-0.40.40.40.3-0.3-0.3-0.1-0.10.2-0.3-0.30.30.3-0.30.30.2-0.30.3-0.5-0.50.10.10.1-0.10.7
Retroperitoneal fat weight0.41.23.00.11.71.7-1.3-1.2-1.21.11.11.11.1-1.11.21.2-1.2-1.21.2-1.2-1.20.9-0.90.90.9-1.1-1.1-0.50.30.5
Reaction time number correct0.30.51.7-1.31.31.3-1.0-0.9-0.80.70.70.60.6-0.60.50.5-0.5-0.50.5-0.5-0.50.5-0.50.50.5-0.6-0.60.2-0.3-0.4
Reaction time mean minus median0.70.91.30.4-1.1-1.11.11.11.1-1.1-1.1-1.0-1.01.0-0.9-0.90.90.9-0.90.90.9-1.11.1-0.9-0.91.01.00.7-0.6-0.8
Reaction time mean minus median AUC0.20.21.1-0.5-0.7-0.70.30.20.10.00.00.10.1-0.20.40.4-0.4-0.40.4-0.4-0.30.2-0.20.20.2-0.2-0.2-0.91.10.9
Reaction time num false alarms0.00.00.3-0.60.30.3-0.2-0.2-0.20.10.10.10.1-0.10.00.0-0.0-0.00.0-0.0-0.10.0-0.00.10.1-0.1-0.10.2-0.2-0.3
Reaction time num false alarms AUC0.10.10.7-0.90.60.6-0.4-0.3-0.20.20.20.10.1-0.10.10.1-0.1-0.10.1-0.1-0.10.1-0.10.10.1-0.1-0.10.4-0.4-0.6
Reaction time trials correct on left0.30.51.7-1.31.31.3-1.0-0.9-0.80.70.70.60.6-0.60.50.5-0.5-0.50.5-0.5-0.50.5-0.50.50.5-0.6-0.60.2-0.3-0.4
Reaction time trials on left0.40.51.7-1.31.31.3-1.0-0.9-0.80.70.70.60.6-0.60.60.6-0.6-0.60.6-0.6-0.60.5-0.50.60.6-0.6-0.60.1-0.2-0.3
Reaction time mean0.10.20.7-0.5-0.4-0.40.10.1-0.00.10.10.30.3-0.30.40.4-0.4-0.40.4-0.4-0.40.2-0.20.20.2-0.3-0.3-0.70.80.8
Reaction time mean AUC0.20.20.9-0.3-0.3-0.30.0-0.0-0.10.20.20.40.4-0.40.50.5-0.5-0.50.5-0.5-0.50.3-0.30.30.3-0.4-0.4-0.80.90.9
Median of all reaction times0.50.71.7-0.80.10.1-0.4-0.5-0.60.70.70.80.8-0.81.01.0-1.0-1.01.0-1.0-0.90.7-0.70.70.7-0.8-0.8-1.21.21.3
Reaction time omissions0.20.20.40.6-0.6-0.60.70.60.6-0.6-0.6-0.5-0.50.5-0.4-0.40.40.4-0.40.40.4-0.60.6-0.5-0.50.50.50.3-0.3-0.1
Reaction time false alarm rate0.00.00.2-0.4-0.1-0.1-0.0-0.0-0.10.10.10.10.1-0.10.10.1-0.1-0.10.1-0.1-0.10.1-0.10.10.1-0.1-0.1-0.10.20.1
Reaction time premature initiation rate1.31.83.81.9-0.6-0.61.01.11.2-1.3-1.3-1.3-1.31.3-1.4-1.41.41.4-1.41.41.3-1.41.4-1.4-1.41.31.31.5-1.7-1.3
Reaction time premature initiations1.01.33.71.40.00.00.60.70.9-1.0-1.0-1.1-1.11.1-1.2-1.21.21.2-1.21.21.2-1.21.2-1.2-1.21.11.11.8-1.9-1.6
Std. dev. reaction times0.20.20.7-0.3-0.8-0.80.70.70.6-0.6-0.5-0.5-0.50.4-0.2-0.20.20.2-0.20.20.3-0.50.5-0.4-0.40.40.40.10.1-0.1
Reaction time trials completed0.40.51.7-1.31.31.3-1.0-0.9-0.80.70.70.60.6-0.60.60.6-0.6-0.60.6-0.6-0.60.5-0.50.60.6-0.6-0.60.1-0.2-0.3
Reaction time trials AUC0.30.51.8-1.31.41.4-0.9-0.9-0.70.60.60.50.5-0.50.50.5-0.5-0.50.5-0.5-0.50.4-0.40.50.5-0.5-0.50.3-0.4-0.5
Run reversals in cocaine runway, females0.50.52.0-0.2-1.4-1.40.90.80.8-0.7-0.7-0.5-0.50.6-0.8-0.80.80.8-0.80.80.8-0.50.5-0.5-0.50.60.60.10.1-0.1
Run reversals in cocaine runway, males1.01.02.40.4-1.5-1.61.21.21.1-1.0-1.0-0.9-0.90.9-1.1-1.11.11.1-1.11.11.0-0.91.0-1.1-1.10.90.90.5-0.30.0
Latency to leave start box in cocaine runway0.70.72.11.3-1.4-1.41.21.21.0-0.9-0.9-0.8-0.80.8-0.6-0.60.60.6-0.60.60.6-0.90.8-0.7-0.70.60.60.00.10.6
Latency to leave start box in cocaine runway, F0.40.43.8-0.2-0.8-0.80.30.20.00.20.20.40.4-0.40.50.5-0.5-0.50.5-0.5-0.50.2-0.20.20.2-0.5-0.5-1.21.31.9
Latency to leave start box in cocaine runway, M3.53.45.81.8-1.2-1.01.61.71.8-1.9-1.9-2.0-2.02.0-1.8-1.81.81.8-1.81.81.9-2.01.9-1.7-1.72.02.02.1-2.1-2.4
Std. dev. time between licks in bursts0.60.71.81.0-1.3-1.31.11.11.0-0.9-0.9-0.7-0.70.7-0.7-0.70.70.7-0.70.70.7-0.80.8-0.8-0.80.70.70.10.00.3
Total sessions with >9 infusions0.10.11.4-1.2-0.5-0.50.20.10.10.00.00.10.1-0.10.20.2-0.2-0.20.2-0.2-0.20.1-0.1-0.1-0.1-0.2-0.2-0.50.60.9
Short access day 1 total inactive lever presses0.00.00.1-0.2-0.1-0.10.20.20.2-0.2-0.2-0.2-0.20.2-0.2-0.20.20.2-0.20.20.2-0.20.2-0.3-0.30.20.20.2-0.2-0.0
Short access day 10 total inactive lever presses0.20.20.80.90.20.20.20.20.3-0.3-0.3-0.4-0.40.4-0.4-0.40.40.4-0.40.40.4-0.40.4-0.2-0.20.40.40.7-0.8-0.9
Short access day 1 total infusions0.10.10.9-0.6-0.7-0.70.40.40.3-0.2-0.2-0.2-0.20.10.00.0-0.0-0.00.0-0.0-0.0-0.10.1-0.3-0.3-0.0-0.0-0.30.51.0
Short access day 10 total infusions0.00.10.9-0.90.00.00.10.10.1-0.1-0.1-0.2-0.20.20.10.1-0.1-0.10.1-0.1-0.1-0.20.2-0.3-0.3-0.1-0.10.2-0.10.3
Short access total infusions0.10.12.2-1.5-0.3-0.30.10.10.1-0.00.0-0.0-0.0-0.00.20.2-0.2-0.20.2-0.2-0.20.0-0.0-0.1-0.1-0.2-0.2-0.30.40.7
Short access day 1 locomotion0.70.73.21.8-0.9-0.91.01.01.0-0.9-0.9-0.9-0.90.9-0.7-0.70.70.7-0.70.70.7-0.90.9-1.0-1.00.70.70.5-0.40.5
Short access day 10 total locomotion4.65.26.92.6-1.7-1.72.22.22.3-2.3-2.3-2.4-2.42.4-2.3-2.32.32.3-2.32.32.3-2.42.4-2.5-2.52.32.32.3-2.2-1.7
Short access total locomotion0.80.91.30.9-1.0-1.01.11.11.0-1.0-1.0-1.1-1.11.0-0.8-0.80.80.8-0.80.80.8-1.01.0-1.1-1.10.80.80.7-0.6-0.0
One hour access (0.3 mA shock)0.20.20.40.00.70.7-0.5-0.5-0.50.50.50.40.4-0.40.50.5-0.5-0.50.5-0.5-0.50.4-0.40.40.4-0.5-0.5-0.30.20.7
Compulsive drug intake1.01.01.6-0.30.70.7-1.0-1.0-1.11.11.11.21.2-1.20.90.9-0.9-0.90.9-0.9-0.91.2-1.21.31.3-0.9-0.9-1.21.10.7
One hour access (shock baseline)0.10.10.50.60.30.30.10.20.2-0.3-0.3-0.4-0.40.4-0.2-0.20.20.2-0.20.20.2-0.40.4-0.5-0.50.20.20.6-0.7-0.2
Social response proportion0.50.51.20.5-1.1-1.10.80.80.8-0.7-0.7-0.7-0.70.7-0.8-0.80.80.8-0.80.80.8-0.60.6-0.7-0.70.70.70.3-0.2-0.2
Social responses6.68.513.42.7-3.7-3.73.33.23.2-3.0-3.0-3.0-3.03.0-3.0-3.03.03.0-3.03.03.0-2.82.8-2.8-2.83.03.01.8-1.5-1.4
Social time0.60.81.3-0.61.11.1-1.0-1.0-1.00.90.90.90.9-0.90.90.9-0.9-0.90.9-0.9-0.90.9-0.90.80.8-0.9-0.9-0.60.50.4
Soleus weight8.725.628.4-5.34.94.9-5.3-5.3-5.35.35.35.25.2-5.25.25.2-5.2-5.25.2-5.2-5.25.2-5.25.25.2-5.1-5.1-4.23.83.4
Bone: stiffness3.45.46.1-2.11.81.8-2.2-2.2-2.32.32.32.52.5-2.52.52.5-2.5-2.52.5-2.5-2.52.3-2.32.32.3-2.4-2.4-2.32.22.3
Tibialis anterior weight1.03.34.3-1.91.61.6-1.9-1.9-1.91.91.91.81.8-1.81.81.8-1.8-1.81.8-1.8-1.82.0-2.02.12.1-1.8-1.8-1.61.50.8
Time to tail flick, vehicle, before self-admin0.40.42.1-0.0-1.4-1.40.90.80.7-0.6-0.6-0.5-0.50.5-0.5-0.50.50.5-0.50.50.5-0.50.5-0.4-0.40.50.5-0.30.50.2
Time to tail flick, vehicle, after self-admin0.30.31.6-0.60.10.10.10.20.3-0.4-0.4-0.4-0.40.4-0.6-0.60.60.6-0.60.60.6-0.40.4-0.4-0.40.50.50.8-0.8-1.2
Time to tail flick, test, before self-admin0.20.21.1-1.1-1.0-1.00.50.50.4-0.2-0.2-0.1-0.10.1-0.1-0.10.10.1-0.10.10.1-0.20.2-0.2-0.20.00.0-0.50.80.9
Time to tail flick, test, after self-admin0.10.20.7-0.6-0.8-0.80.50.50.4-0.3-0.3-0.3-0.30.3-0.2-0.20.20.2-0.20.20.2-0.30.3-0.2-0.20.20.2-0.20.30.5
Delta time to tail flick, vehicle, before/after SA0.40.31.7-0.91.31.3-0.9-0.8-0.60.50.50.40.4-0.40.30.3-0.3-0.30.3-0.3-0.30.4-0.40.30.3-0.3-0.30.5-0.6-0.8
Delta time to tail flick, test, before/after SA0.30.20.80.80.10.10.20.20.3-0.4-0.4-0.5-0.50.5-0.5-0.50.50.5-0.50.50.5-0.50.5-0.5-0.50.40.40.8-0.9-0.7
Tibia length1.02.83.71.9-1.3-1.31.61.61.7-1.7-1.7-1.8-1.81.8-1.7-1.71.71.7-1.71.71.7-1.71.7-1.6-1.61.81.81.5-1.5-1.4
Ambulatory time before self-admin0.20.20.4-0.40.40.4-0.4-0.5-0.50.50.50.40.4-0.40.50.5-0.5-0.50.5-0.5-0.50.5-0.50.60.6-0.5-0.5-0.50.40.3
Ambulatory time after self-admin0.50.50.90.9-0.8-0.80.80.80.8-0.7-0.7-0.7-0.70.7-0.7-0.70.70.7-0.70.70.7-0.70.7-0.6-0.60.80.80.5-0.5-0.6
Bone: tissue strength2.12.02.5-1.31.21.2-1.3-1.3-1.41.41.41.51.5-1.51.61.6-1.6-1.61.6-1.6-1.61.4-1.41.41.4-1.5-1.5-1.31.21.3
Total heroin consumption1.82.12.70.6-1.6-1.61.61.61.6-1.6-1.6-1.5-1.51.5-1.4-1.41.41.4-1.41.41.4-1.61.6-1.5-1.51.41.41.2-0.9-1.0
Bone: trabecular number0.50.83.31.0-1.8-1.81.21.11.0-0.8-0.8-0.7-0.70.7-0.7-0.70.70.7-0.70.70.7-0.60.6-0.6-0.60.70.7-0.30.50.6
Bone: trabecular spacing0.40.52.9-0.71.71.7-0.9-0.8-0.60.40.30.10.1-0.10.10.1-0.1-0.10.1-0.1-0.10.1-0.10.10.1-0.1-0.11.1-1.2-1.6
Bone: trabecular thickness0.91.17.40.1-1.6-1.60.40.2-0.10.40.40.70.7-0.70.70.7-0.7-0.70.7-0.7-0.70.7-0.70.70.7-0.7-0.7-2.12.32.7
Bone: trabecular tissue density1.82.65.5-1.62.32.3-1.9-1.8-1.71.61.61.61.6-1.61.71.7-1.7-1.71.7-1.7-1.71.4-1.41.41.4-1.6-1.6-0.60.40.6
Water consumed over 24 hours0.80.92.0-0.80.30.3-0.7-0.7-0.80.90.91.01.0-1.01.01.0-1.0-1.01.0-1.0-1.01.0-1.01.01.0-1.0-1.0-1.31.31.4
Number of responses in last shaping day0.10.10.30.3-0.4-0.40.50.50.5-0.5-0.4-0.4-0.40.4-0.3-0.30.30.3-0.30.30.3-0.40.4-0.5-0.50.30.30.3-0.30.2