Hub : Genes

Mafg

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA intron excision ratio chr10_105908109_105910978 0.07 0.05 2.9e-03 0.06 0.07 0.05 0.06 1.3e-03 8.5e-04 3.2e-03 9.2e-04
2 OFC alternative TSS XM_006247922.4 0.15 0.11 8.5e-03 -0.01 -0 -0 -0 5.5e-01 3.5e-01 4.1e-01 3.8e-01
3 LHb isoform ratio NM_022386.3 0.16 0.11 9.4e-03 0.02 -0.01 0.02 0 1.1e-01 8.4e-01 1.0e-01 2.6e-01
4 LHb isoform ratio XM_008768482.3 0.17 0.11 4.6e-03 0.04 0.03 0.07 0.03 5.3e-02 7.9e-02 1.2e-02 7.2e-02
5 pVTA gene expression Mafg 0.18 0.1 8.1e-06 0.13 0.13 0.13 0.12 2.1e-06 3.5e-06 3.8e-06 5.5e-06
6 NAcc gene expression Mafg 0.24 0.09 0.0e+00 0.24 0.22 0.21 0.22 4.0e-27 1.5e-25 2.5e-24 1.3e-25
7 PL alternative TSS NM_022386.3 0.03 0.02 9.9e-03 0.01 0.02 0.01 0.01 2.8e-02 2.9e-03 1.8e-02 8.6e-03
8 BLA gene expression Mafg 0.5 0.16 5.3e-14 0.23 0.25 0.25 0.26 2.4e-12 1.5e-13 1.0e-13 2.3e-14
9 PL gene expression Mafg 0.26 0.09 0.0e+00 0.3 0.29 0.27 0.3 7.5e-33 1.3e-31 4.6e-30 7.2e-33
10 PL alternative TSS XM_006247922.4 0.04 0.03 6.0e-04 0.03 0.02 0.02 0.02 1.8e-04 1.6e-03 1.7e-03 1.3e-03
11 IL gene expression Mafg 0.56 0.15 2.4e-09 0.28 0.28 0.28 0.32 1.8e-07 1.5e-07 1.7e-07 2.5e-08
12 OFC gene expression Mafg 0.43 0.16 2.1e-06 0.16 0.18 0.21 0.2 1.2e-04 4.0e-05 8.5e-06 2.2e-05
13 Brain gene expression Mafg 0.1 0.06 2.2e-07 0.08 0.08 0.07 0.08 7.5e-08 7.1e-08 9.8e-07 1.3e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.30.51.3-0.6-0.30.3-0.41.20.8-0.8-0.9-0.8-0.8-0.50.3-0.7
Area under the delay curve0.70.82.11.41.4-1.31.2-0.8-0.80.60.50.80.5-0.3-0.00.2
BMI with tail0.62.04.7-1.6-1.21.3-1.31.31.8-1.5-2.2-1.5-1.2-1.40.5-1.2
BMI without tail7.214.818.7-4.1-2.93.8-4.24.34.2-4.3-4.0-4.2-4.3-3.12.6-3.3
Body weight2.08.419.8-4.5-4.14.1-4.02.72.9-2.3-2.1-2.7-2.3-0.70.5-1.1
Weight adjusted by age1.01.13.5-1.8-1.91.4-1.40.60.8-0.3-1.4-0.5-0.1-0.2-0.30.2
Bone surface0.10.20.4-0.7-0.60.6-0.70.60.4-0.30.2-0.4-0.50.40.2-0.1
Bone volume0.20.30.9-0.7-0.60.6-0.60.90.6-0.5-0.4-0.6-0.8-0.10.1-0.4
Breakpoint value in progressive ratio session0.50.61.6-0.5-1.00.8-0.1-0.8-0.60.90.00.71.00.4-0.81.3
Number of licking bursts0.40.51.0-0.4-0.1-0.1-0.50.91.0-0.8-0.4-0.9-1.0-0.50.6-0.9
Context. condit. distance diff. score3.13.76.6-1.0-0.21.2-1.11.92.3-2.2-2.2-2.2-2.4-2.02.6-2.1
Locomotion velocity, session 13.23.45.41.91.2-1.61.5-2.0-2.32.11.92.31.91.7-1.61.8
Locomotion distance, session 11.01.34.71.82.2-1.71.60.1-0.0-0.3-0.4-0.0-0.4-1.11.0-1.0
Locomotion velocity, session 22.73.27.02.62.4-1.92.4-1.8-1.71.52.01.71.71.0-0.40.7
Locomotion distance, session 20.50.71.40.61.0-0.30.30.90.6-0.9-0.8-0.7-0.8-1.01.1-1.2
Locomotion velocity, session 31.92.23.71.71.3-1.71.6-1.7-1.61.61.11.61.90.8-0.61.1
Locomotion distance, session 31.71.94.42.12.0-1.92.0-1.5-1.21.10.81.21.10.10.10.4
Stereotopy head waving bouts, day 30.81.01.91.00.7-1.00.9-1.0-1.11.11.21.11.40.8-0.30.9
Stereotopy head waving duration, day 30.30.40.60.70.6-0.70.6-0.5-0.60.60.80.60.70.20.20.4
Locomotion velocity, session 70.30.31.01.01.0-0.81.0-0.5-0.20.2-0.00.3-0.1-0.40.2-0.1
Locomotion distance, session 71.31.75.21.72.3-1.41.6-0.10.4-0.6-1.1-0.4-0.7-1.71.4-1.3
Stereotopy head waving bouts, day 70.10.20.3-0.4-0.40.5-0.40.40.4-0.3-0.2-0.3-0.2-0.60.5-0.1
Stereotopy head waving duration, day 70.20.20.7-0.6-0.70.9-0.60.40.4-0.10.5-0.30.10.00.30.1
Locomotion velocity, session 80.80.92.10.51.00.10.30.90.9-1.2-0.9-1.0-0.9-1.01.3-1.5
Locomotion distance, session 84.46.411.5-0.70.50.9-0.92.72.9-3.0-2.9-2.9-3.0-3.03.4-3.1
Degree of sensitization distance1.51.52.6-1.0-0.51.1-1.01.41.4-1.4-1.5-1.4-1.6-1.00.7-1.2
Degree of sensitization stereotypy0.40.50.9-0.8-0.70.9-0.80.80.8-0.5-0.6-0.7-0.5-0.70.5-0.3
Conditioned locomotion4.14.77.4-2.6-2.12.2-2.72.72.4-2.2-2.0-2.4-2.5-1.30.8-1.6
Cocaine response after cond. corrected0.30.40.80.3-0.1-0.60.3-0.7-0.90.70.10.80.40.4-0.90.8
Cocaine response after cond. not corrected0.50.61.10.80.5-0.90.8-0.8-1.10.80.60.90.60.5-0.80.7
Cocaine response before conditioning0.30.41.61.01.3-0.51.10.00.1-0.20.7-0.10.1-0.10.5-0.6
Saline control response1.62.25.0-2.2-2.12.1-2.01.51.3-1.2-0.8-1.3-1.3-0.20.3-0.5
Bone: connectivity density0.50.71.6-0.10.40.2-0.21.01.0-1.0-0.5-1.1-1.1-0.51.2-1.2
Bone: cortical apparent density1.72.36.22.11.8-2.51.9-1.6-1.51.30.41.51.60.1-0.50.8
Bone: cortical area2.43.610.9-3.2-3.32.8-2.71.91.2-0.9-0.4-1.2-0.90.6-1.30.1
Bone: cortical porosity2.93.27.2-0.5-1.50.1-0.2-1.6-1.92.01.52.02.22.0-2.72.5
Bone: cortical porosity1.92.04.7-0.7-1.50.4-0.5-1.1-1.41.51.11.41.81.5-2.22.0
Bone: cortical thickness1.93.110.9-2.9-3.32.4-2.41.10.3-0.00.2-0.30.11.4-2.21.0
Bone: cortical thickness0.60.72.6-1.4-1.60.9-1.10.70.2-0.1-0.5-0.2-0.10.2-1.20.4
Bone: cortical tissue density2.02.67.02.22.0-2.62.1-1.7-1.61.40.51.61.70.1-0.50.8
Condit. Reinf. active minus inactive responses1.51.73.8-1.9-1.72.0-1.81.31.2-1.1-1.1-1.2-1.2-0.40.3-0.6
Condit. Reinf. active-inactive response ratio0.60.61.4-1.2-1.10.9-1.00.80.7-0.6-1.1-0.7-0.6-0.50.1-0.3
Condit. Reinf. active responses3.03.67.2-2.6-2.32.7-2.72.11.8-1.7-1.4-1.8-1.8-0.50.6-1.0
Condit. Reinf. inactive responses1.01.12.8-1.3-1.21.7-1.61.10.9-1.0-0.6-1.0-1.2-0.20.4-0.6
Incentive salience index mean1.41.73.7-1.7-1.41.9-1.71.41.3-1.2-0.9-1.3-1.3-0.40.5-0.8
Condit. Reinf. lever presses0.30.40.8-0.10.20.5-0.10.80.9-0.8-0.3-0.8-0.7-0.70.9-0.9
Condit. Reinf. active minus inactive responses0.70.92.1-1.2-1.11.5-1.41.00.8-0.9-0.5-0.9-0.9-0.00.3-0.5
Condit. Reinf. active-inactive response ratio1.11.13.4-1.7-1.81.8-1.90.90.3-0.40.0-0.4-0.50.8-0.50.2
Condit. Reinf. active responses0.40.61.0-0.7-0.50.8-1.00.90.7-0.9-1.0-0.8-0.9-0.50.5-0.7
Condit. Reinf. inactive responses0.20.30.70.60.8-0.70.5-0.10.1-0.2-0.8-0.1-0.2-0.80.6-0.5
Condit. Reinf. lever presses0.71.03.6-0.6-0.30.2-0.81.10.9-1.1-1.9-1.0-1.0-1.30.5-1.0
Condit. Reinf. lever reinforcers received0.71.02.8-0.7-0.40.6-1.01.10.9-1.1-1.7-1.0-1.1-1.00.8-0.9
Conditioned reinforcement - actives0.50.51.3-0.10.2-0.5-0.10.80.8-0.8-0.4-0.9-0.5-0.71.1-0.9
Conditioned reinforcement - inactives0.60.61.9-1.3-1.41.4-1.20.50.4-0.3-0.6-0.4-0.50.3-0.10.1
Conditioned locomotion0.10.10.3-0.2-0.1-0.1-0.10.30.5-0.30.0-0.5-0.3-0.30.5-0.3
Patch foraging indifference point 0 sec0.00.10.2-0.4-0.4-0.0-0.30.20.1-0.1-0.4-0.0-0.2-0.50.30.1
Patch foraging indifference point AUC0.10.10.4-0.10.0-0.1-0.40.50.0-0.4-0.4-0.3-0.7-0.20.3-0.3
Delay disc. indifference point, 0s delay0.00.00.30.20.2-0.10.2-0.00.00.1-0.30.10.1-0.50.10.0
Delay disc. indifference point, 16s delay1.11.22.91.31.7-1.41.10.20.2-0.6-0.9-0.2-0.3-1.71.3-1.1
Delay disc. indifference point, 2s delay0.30.30.50.70.6-0.30.7-0.7-0.70.60.60.60.5-0.2-0.20.5
Delay disc. indifference point, 24s delay3.93.86.62.62.1-2.42.5-2.2-2.01.91.92.01.80.9-0.91.2
Delay disc. indifference point, 4s delay0.30.30.80.80.6-0.90.6-0.3-0.60.50.70.50.30.3-0.20.3
Delay disc. indifference point, 8s delay0.91.01.51.10.7-0.90.8-1.2-1.21.11.21.10.90.8-0.70.9
Indifference point function ln k0.40.61.81.11.2-1.11.4-0.6-0.30.3-0.00.50.7-0.40.1-0.1
Indifference point function log k0.40.61.81.11.2-1.11.4-0.6-0.30.3-0.00.50.7-0.40.1-0.1
Patch foraging total patch changes 0 sec0.10.10.5-0.4-0.3-0.1-0.40.30.2-0.2-0.7-0.2-0.3-0.70.4-0.1
Patch foraging total patch changes 12 sec0.10.10.3-0.1-0.3-0.1-0.3-0.0-0.60.20.20.3-0.40.2-0.40.4
Patch foraging total patch changes 18 sec0.50.72.00.10.4-0.7-0.11.00.5-0.8-1.4-0.6-0.7-1.41.0-0.9
Patch foraging total patch changes 24 sec0.40.41.3-0.9-0.80.3-0.70.70.6-0.6-1.1-0.5-0.6-0.60.2-0.3
Patch foraging total patch changes 6 sec0.10.20.7-0.7-0.90.3-0.70.2-0.20.10.20.1-0.10.3-0.10.4
Patch foraging time to switch 0 sec0.30.50.90.90.8-1.00.9-0.7-0.60.60.80.70.80.3-0.20.3
Patch foraging water rate 0 sec1.93.04.9-2.2-1.82.2-2.21.81.7-1.7-1.9-1.7-1.7-1.20.9-1.1
Patch foraging water rate 12 sec0.91.32.5-0.7-0.20.7-0.61.21.3-1.4-1.6-1.3-0.7-1.51.5-1.3
Patch foraging water rate 18 sec1.41.93.0-1.1-0.51.2-0.91.61.7-1.7-1.4-1.7-1.3-1.61.3-1.5
Patch foraging water rate 24 sec3.65.010.0-1.9-1.21.4-1.82.32.5-2.4-3.2-2.4-1.9-2.82.2-2.0
Patch foraging water rate 6 sec0.40.51.0-0.4-0.10.8-0.40.61.0-0.9-0.6-0.9-0.7-0.70.9-0.9
Seeking ratio, delayed vs. immediate footshock1.01.12.3-1.5-1.31.0-1.41.41.2-1.0-0.8-1.1-0.9-0.10.3-0.5
Distance traveled before self-admin0.80.82.3-1.1-1.51.2-0.6-0.6-0.20.80.30.40.50.7-1.41.2
Distance traveled after self-admin0.70.81.4-0.9-0.60.9-0.91.00.9-1.0-1.2-0.9-0.8-0.90.9-0.8
Extensor digitorum longus weight0.83.26.5-0.70.20.6-0.61.92.1-2.1-2.6-2.1-1.7-2.51.8-2.1
Bone: elastic displacement0.50.52.1-1.2-1.40.6-1.00.4-0.00.1-0.00.00.10.4-1.10.6
Bone: elastic work2.93.713.3-2.9-3.72.3-2.50.3-0.40.60.30.40.21.7-2.71.8
Bone: endosteal estimation0.61.22.2-0.20.30.2-0.21.31.2-1.2-1.2-1.2-1.4-1.51.4-1.3
Bone: endosteal perimeter0.30.61.5-1.2-1.21.2-0.90.80.6-0.5-0.1-0.7-0.80.3-0.3-0.1
Epididymis fat weight0.92.13.8-1.8-1.31.4-1.41.41.9-1.5-1.7-1.7-1.1-1.10.8-1.2
Delta time in closed arm before/after self-admin0.20.20.40.20.4-0.4-0.10.60.2-0.50.5-0.3-0.60.10.6-0.6
Delta time in open arm before/after self-admin0.20.21.1-0.10.00.30.0-0.10.5-0.2-1.1-0.3-0.1-1.00.6-0.3
Diff in mean of infusions in LGA sessions0.40.51.70.60.4-0.81.1-0.8-0.50.80.60.61.30.1-0.10.6
Delay discount exponential model param1.21.33.0-1.7-1.51.6-1.51.11.2-0.9-0.9-1.1-0.8-0.10.3-0.5
Extinction: sum of active levers before priming1.81.84.01.51.1-0.61.8-2.0-1.11.50.61.32.00.4-1.01.1
Active lever presses in extinction session 61.61.63.60.70.10.21.2-1.9-1.41.70.51.51.90.5-1.11.6
Bone: final force2.43.810.7-3.3-3.33.0-2.81.81.4-1.2-1.0-1.4-1.4-0.1-0.5-0.1
Bone: final moment2.54.112.7-3.5-3.63.0-3.01.81.2-1.0-1.0-1.3-1.2-0.0-0.80.1
Food consumed during 24 hour testing period0.40.53.4-0.8-0.71.8-0.80.10.5-0.5-0.5-0.5-0.5-0.5-0.2-0.2
Glucose7.010.517.32.41.1-2.22.3-4.2-4.03.92.54.04.02.7-3.43.6
Heart weight0.20.30.8-0.9-0.90.8-0.80.40.4-0.2-0.7-0.3-0.3-0.2-0.10.0
Delay discount hyperbolic model param1.21.22.9-1.7-1.51.5-1.51.11.2-0.9-0.9-1.1-0.8-0.00.2-0.5
Intermittent access intake day 1-15 change0.40.41.3-1.0-1.11.0-1.00.6-0.0-0.2-0.4-0.3-0.30.2-0.70.2
Intermittent access intake escalation0.40.41.0-1.0-1.00.9-1.00.80.2-0.5-0.5-0.4-0.5-0.1-0.2-0.1
Intermittent access intake escalation 20.90.83.3-1.4-1.81.4-1.10.2-0.20.40.10.10.20.6-1.01.0
Intermitt. access day 1 inactive lever presses0.60.63.5-1.1-1.31.9-0.9-0.1-0.00.1-0.40.1-0.00.3-0.60.5
Intermitt. access day 15 inactive lever presses1.01.11.7-1.2-0.91.3-1.21.11.1-1.2-1.2-1.0-1.1-0.80.6-0.9
Intermitt. access escalation Index1.81.62.5-1.0-0.50.9-1.21.41.4-1.6-1.0-1.4-1.5-1.11.5-1.4
Intermittent access day 1 total infusions0.30.40.7-0.8-0.60.5-0.90.60.8-0.6-0.4-0.6-0.7-0.10.5-0.4
Intermittent access day 15 total infusions0.70.71.3-1.1-0.90.9-1.21.00.9-0.8-0.9-0.9-0.9-0.40.4-0.5
Intermittent access terminal intake (last 3 days)0.70.81.8-1.3-1.31.0-1.31.00.8-0.6-0.6-0.8-0.8-0.20.2-0.2
Intermittent access total infusions0.50.61.1-1.0-0.80.8-1.10.90.9-0.8-0.5-0.9-0.9-0.30.5-0.5
Intermittent access day 1 locomotion0.50.50.8-0.7-0.40.5-0.80.70.9-0.8-0.7-0.9-0.8-0.60.8-0.7
Intermittent access day 15 total locomotion0.20.20.7-0.7-0.80.6-0.80.40.2-0.10.3-0.3-0.50.40.20.1
Intermittent access total locomotion0.30.30.8-0.8-0.70.9-0.90.50.5-0.5-0.2-0.6-0.7-0.00.3-0.2
Intermittent access standard deviation1.71.84.00.6-0.0-0.11.0-1.6-1.41.81.01.51.71.1-2.01.8
Left kidney weight0.20.41.9-0.1-0.4-0.0-0.1-0.3-0.50.61.40.50.21.2-0.60.7
Right kidney weight0.10.21.00.20.1-0.40.1-0.1-0.10.21.00.10.00.90.10.1
Cocaine induced anxiety2.42.88.3-2.1-2.92.8-1.3-0.8-0.21.1-0.10.50.91.7-2.12.0
Post-drug Anxiety0.90.92.2-0.6-1.11.0-0.3-0.9-0.71.00.20.80.81.3-1.51.4
Baseline Anxiety2.93.111.22.93.2-3.32.3-0.8-1.10.30.81.00.3-0.30.8-0.8
Tail length4.613.825.2-4.8-3.94.6-5.04.33.7-3.7-2.3-3.8-4.2-1.52.1-2.4
Length with tail1.03.510.4-3.2-3.22.9-3.01.51.3-0.90.0-1.3-1.10.8-0.30.1
Length without tail2.35.18.51.0-0.0-1.01.4-2.4-2.22.82.72.42.92.8-2.42.7
Times rat made contact with spout1.11.22.7-1.0-1.51.7-1.2-0.7-0.80.90.80.80.51.2-1.41.4
Lifetime Intake0.20.20.3-0.5-0.40.5-0.60.50.5-0.5-0.2-0.5-0.6-0.10.4-0.3
Liver weight, left0.91.52.90.5-0.1-0.40.6-1.4-1.31.60.91.41.71.2-1.61.6
Liver weight, right0.91.45.1-1.8-1.72.2-1.60.81.0-0.50.8-0.8-0.90.8-0.4-0.1
Locomotor activity0.50.72.11.11.0-1.51.4-0.7-0.80.70.20.80.8-0.2-0.30.3
Locomotor testing distance0.60.93.81.31.4-2.01.6-0.4-0.30.2-0.50.40.6-0.90.3-0.3
Locomotor testing rearing0.20.40.90.70.9-0.90.90.10.1-0.2-0.70.00.2-0.90.6-0.5
Locomotion in novel chamber0.20.20.50.40.6-0.30.5-0.20.5-0.3-0.6-0.2-0.3-0.70.7-0.5
Locomotion in novel chamber post-restriction1.41.64.0-1.9-1.81.9-2.01.30.9-0.9-0.0-1.1-1.40.6-0.1-0.3
Fecal boli incidents, locomotor time 10.20.20.90.81.0-0.70.6-0.2-0.1-0.00.20.10.0-0.1-0.0-0.3
Change in fecal boli incidents, locomotor task3.33.14.61.50.8-2.01.7-1.7-2.02.02.12.02.01.5-1.01.8
Time >=10cm from walls, locomotor time 11.91.94.0-0.9-0.30.5-1.31.71.7-1.7-0.7-1.6-2.0-0.71.6-1.6
Bouts of movement, locomotor time 11.11.23.01.51.4-1.41.7-1.4-0.90.90.20.91.10.5-0.60.4
Total resting periods, locomotor time 11.61.83.51.71.5-1.51.9-1.6-1.31.30.71.31.30.9-1.00.8
Rest time, locomotor task time 10.70.81.90.60.2-0.30.8-1.0-1.01.01.01.00.91.0-1.40.9
Distance moved, locomotor task time 10.70.81.7-0.9-0.60.4-0.81.01.1-0.9-1.3-1.0-0.8-0.90.5-0.7
Vertical activity count, locomotor time 11.91.93.4-1.2-0.71.2-1.01.41.8-1.5-1.8-1.7-1.3-1.61.0-1.4
Time >=10cm from walls, locomotor time 20.20.20.7-0.20.0-0.2-0.50.70.4-0.40.7-0.5-0.90.20.7-0.5
Bouts of movement, locomotor time 20.40.41.61.21.3-0.71.0-0.7-0.40.1-0.00.30.20.00.2-0.3
Total resting periods, locomotor time 20.30.31.30.91.2-0.60.7-0.30.0-0.3-0.4-0.1-0.1-0.20.6-0.7
Rest time, locomotor task time 20.10.10.40.30.3-0.10.4-0.4-0.20.20.60.10.30.6-0.40.1
Distance moved, locomotor task time 20.10.10.4-0.1-0.1-0.3-0.20.50.3-0.2-0.7-0.2-0.2-0.60.3-0.2
Vertical activity count, locomotor time 20.91.01.9-0.40.10.2-0.41.21.1-1.2-1.3-1.1-1.0-1.41.1-1.2
Light reinforcement 11.62.95.8-1.6-0.91.2-1.41.82.4-2.0-1.8-2.2-1.5-1.51.6-1.8
Light reinforcement 21.72.24.2-1.9-1.51.9-1.51.72.1-1.5-1.0-1.8-1.1-0.70.9-1.1
Bone: marrow area0.51.22.2-0.20.30.1-0.21.31.2-1.2-1.2-1.2-1.4-1.51.4-1.3
Bone: maximum diameter0.61.23.0-1.7-1.71.7-1.21.40.9-0.70.1-0.9-0.60.4-0.5-0.2
Bone: maximum force2.74.611.9-3.5-3.33.2-3.12.21.7-1.5-1.2-1.7-1.7-0.1-0.4-0.4
Bone: maximum moment2.84.813.3-3.6-3.63.3-3.22.11.5-1.3-1.2-1.6-1.50.0-0.7-0.2
Mean time between licks in bursts0.60.93.01.61.7-1.71.4-0.3-0.50.30.30.50.2-0.40.3-0.2
Mean num. licks in bursts0.70.91.8-0.3-0.81.2-0.3-1.1-1.11.00.41.01.00.7-1.21.3
Cd content in liver0.60.62.21.41.5-0.71.2-0.7-0.40.2-0.40.40.6-0.90.2-0.2
Co content in liver0.10.10.30.40.50.00.5-0.5-0.10.1-0.40.1-0.1-0.60.4-0.1
Cu content in liver1.21.42.7-0.2-0.81.0-0.2-1.4-1.41.31.21.30.71.5-1.61.6
Fe content in liver0.50.51.61.21.2-1.21.2-0.3-0.30.2-0.30.30.6-0.6-0.1-0.2
K content in liver2.32.33.7-1.6-1.11.7-1.61.81.7-1.7-0.7-1.7-1.9-0.61.3-1.3
Mg content in liver2.42.44.2-0.60.20.5-0.82.01.9-2.0-0.9-1.9-2.0-1.32.0-2.1
Mn content in liver0.20.20.6-0.5-0.60.6-0.50.20.2-0.10.7-0.1-0.30.60.00.1
Na content in liver0.00.00.30.00.00.10.1-0.3-0.00.20.40.1-0.20.5-0.10.1
Rb content in liver1.62.03.1-1.3-0.81.1-1.51.71.5-1.6-1.1-1.6-1.8-1.11.4-1.3
Se content in liver0.30.30.7-0.7-0.60.2-0.80.80.6-0.6-0.3-0.6-0.7-0.20.4-0.4
Sr content in liver2.62.44.40.5-0.2-1.30.6-1.6-1.91.91.41.92.11.6-1.82.0
Zn content in liver0.30.32.30.20.20.00.0-0.2-0.40.31.50.30.11.1-0.40.2
Bone: minimum diameter1.22.26.8-2.5-2.62.3-2.11.40.9-0.6-0.2-0.9-0.90.3-0.90.2
Time in familiar zone, hab. session 10.30.31.00.1-0.1-0.3-0.0-0.3-0.70.5-0.10.60.70.5-1.00.6
Time in novel zone, hab. session 10.20.21.0-0.10.10.30.00.00.5-0.4-0.1-0.5-0.5-0.41.0-0.5
Total zone transitions, hab. session 10.20.20.70.60.8-0.40.60.20.2-0.3-0.8-0.2-0.0-0.80.3-0.5
Total locomotion distance, hab. session 10.60.82.7-0.4-0.00.5-0.21.01.0-1.0-1.6-1.0-0.8-1.40.7-1.0
Locomotion velocity, hab. session 10.60.92.6-0.4-0.00.5-0.31.01.1-1.0-1.6-1.0-0.8-1.40.6-1.0
Time in familiar zone, hab. session 20.20.21.10.40.5-0.60.4-0.20.0-0.2-1.0-0.1-0.2-0.90.1-0.3
Time in novel zone, hab. session 20.10.10.50.20.2-0.10.20.2-0.00.10.70.00.10.50.2-0.0
Total zone transitions, hab. session 21.62.03.90.10.90.0-0.11.51.5-1.7-1.6-1.6-1.7-1.81.7-2.0
Total locomotion distance, hab. session 22.83.75.7-0.9-0.01.1-1.02.42.3-2.3-1.9-2.3-2.3-2.22.0-2.3
Locomotion velocity, hab. session 22.83.86.1-1.1-0.31.4-1.22.52.3-2.4-1.9-2.4-2.4-2.11.9-2.3
Novel to familiar place preference ratio1.21.24.4-1.6-2.11.5-1.50.0-0.30.50.30.30.40.9-1.11.2
Novelty place preference1.21.24.2-1.6-2.11.4-1.4-0.1-0.40.50.30.40.51.1-1.31.2
Time in novel zone, NPP test0.90.93.4-1.5-1.81.4-1.30.1-0.20.40.10.20.30.8-1.01.0
Total zone transitions, NPP test2.13.05.80.41.3-0.30.11.81.8-2.0-1.9-1.8-2.0-2.22.1-2.4
Total locomotion distance, NPP test3.34.57.4-0.50.60.6-0.62.42.5-2.5-2.3-2.5-2.6-2.62.5-2.7
Locomotion velocity, NPP test2.53.55.5-0.70.20.6-0.72.22.2-2.2-2.1-2.2-2.3-2.32.0-2.3
Intraocular pressure0.71.03.4-1.1-0.90.9-1.31.80.8-1.1-0.7-1.0-1.1-0.70.3-0.8
Delta distance traveled before/after self-admin1.01.02.90.40.9-0.70.21.00.7-1.1-1.3-0.8-0.6-1.31.7-1.4
Delta ambulatory time before/after self-admin1.01.12.81.01.5-1.40.70.70.2-0.9-0.8-0.4-0.3-1.21.7-1.3
Parametrial fat weight0.81.64.3-2.0-1.91.4-2.11.21.0-0.9-0.9-1.0-1.2-0.1-0.2-0.3
Pavlov. Cond. lever latency1.62.06.90.71.3-1.00.60.61.1-1.3-2.6-1.1-1.3-2.21.5-1.7
Pavlov. Cond. magazine entry latency1.41.94.7-1.5-2.21.5-1.5-0.2-0.80.90.90.80.91.7-1.91.6
Pavlov. Cond. change in total contacts1.41.53.1-0.2-0.8-0.0-0.0-1.1-1.41.51.11.51.81.2-1.41.8
Pavlov. Cond. index score1.41.75.2-1.8-2.31.9-1.70.3-0.20.41.20.30.61.5-1.21.1
Pavlov. Cond. latency score1.41.84.2-1.5-2.01.7-1.4-0.1-0.50.81.80.60.91.9-1.31.4
Pavlov. Cond. lever contacts0.70.83.0-0.7-1.00.9-0.60.0-0.40.61.70.50.71.4-0.80.9
Pavlov. Cond. magazine entry number2.12.65.41.32.1-1.21.20.81.3-1.5-1.4-1.4-1.4-2.12.3-2.2
Pavlov. Cond. intertrial magazine entries1.21.42.2-0.7-0.20.5-0.91.51.3-1.4-1.4-1.4-1.5-1.30.9-1.3
Pavlov. Cond. lever-magazine prob. diff.1.41.75.4-1.9-2.31.8-1.70.3-0.20.51.00.30.61.4-1.41.2
Pavlov. Cond. response bias1.72.04.0-1.3-1.91.2-1.2-0.4-1.01.11.51.01.31.9-2.01.7
Pavlov. Cond. lever latency1.52.05.61.10.6-0.81.1-1.6-1.61.62.41.51.31.8-1.01.4
Pavlov. Cond. magazine entry latency1.01.22.91.21.7-1.31.20.20.4-0.7-1.4-0.4-0.4-1.70.8-1.2
Pavlov. Cond. change in total contacts0.81.14.60.20.6-0.60.10.60.9-0.9-2.2-0.8-0.5-1.81.0-1.1
Pavlov. Cond. index score0.81.04.90.10.5-0.60.10.70.8-1.0-2.2-0.8-0.7-1.80.7-1.1
Pavlov. Cond. latency score1.01.35.00.00.5-0.4-0.00.91.0-1.1-2.2-1.0-0.9-1.90.9-1.3
Pavlov. Cond. lever contacts2.02.86.3-1.3-0.71.0-1.31.81.9-1.9-2.5-1.9-1.5-2.01.3-1.6
Pavlov. Cond. magazine entry number1.01.23.2-1.0-1.51.3-1.0-0.4-0.60.81.60.60.61.8-0.91.2
Pavlov. Cond. intertrial magazine entries1.11.53.7-1.7-1.61.6-1.91.41.0-1.0-0.5-1.2-1.1-0.10.6-0.5
Pavlov. Cond. lever-magazine prob. diff.0.81.14.90.30.7-0.70.20.70.8-0.9-2.2-0.7-0.6-1.80.8-1.1
Pavlov. Cond. response bias1.11.54.7-0.50.00.2-0.41.21.3-1.4-2.2-1.3-1.0-1.90.9-1.3
Time in closed arm before self-admin0.70.81.70.3-0.1-0.00.4-1.0-0.91.10.70.91.01.0-1.31.2
Time in closed arm after self-admin2.32.34.00.90.3-0.50.9-1.5-1.81.81.91.71.52.0-2.01.7
Time in open arm before self-admin0.30.31.20.40.6-0.90.20.50.3-0.50.5-0.3-0.4-0.21.1-0.7
Time in open arm after self-admin0.40.41.60.30.6-0.40.20.30.6-0.6-0.7-0.5-0.4-1.01.3-0.8
Bone: periosteal estimation1.12.25.0-2.2-2.01.9-1.82.01.4-1.2-0.9-1.5-1.4-0.5-0.1-0.6
Bone: periosteal perimeter1.32.17.0-2.2-2.62.1-1.70.60.00.30.9-0.00.21.6-1.91.1
Bone: post-yield work0.40.61.0-0.10.30.2-0.21.00.9-0.9-0.9-0.9-0.7-0.70.9-1.0
Progressive ratio test 1 active lever presses0.90.91.7-1.3-1.11.2-1.20.91.1-0.9-0.7-1.1-0.9-0.30.7-0.6
Progressive ratio test 1 breakpoint1.11.12.2-1.5-1.31.4-1.41.01.2-1.0-0.8-1.2-1.0-0.20.6-0.6
Progressive ratio test 1 inactive lever presses1.92.14.6-1.9-1.62.2-1.71.21.5-1.3-1.5-1.5-1.3-0.90.7-0.8
Progressive ratio test 2 active lever presses0.30.30.8-0.8-0.70.5-0.90.60.5-0.4-0.0-0.5-0.60.30.0-0.2
Progressive ratio test 2 breakpoint0.50.51.0-0.9-0.70.6-1.01.00.8-0.8-0.3-0.9-0.9-0.10.4-0.6
Progressive ratio test 2 inactive lever presses0.20.20.7-0.7-0.80.6-0.70.30.1-0.1-0.1-0.1-0.20.3-0.00.2
Incentive Sensitization - Responses0.20.20.6-0.6-0.50.3-0.80.70.2-0.4-0.1-0.3-0.50.4-0.4-0.2
Incentive Sensitization - Breakpoint0.10.10.4-0.5-0.50.2-0.70.50.1-0.2-0.0-0.2-0.40.5-0.5-0.0
Sum of active levers in priming session hrs 5-60.50.41.5-0.8-1.20.8-0.6-0.3-0.50.6-0.50.50.5-0.1-0.31.1
Progressive ratio0.30.30.70.80.8-0.60.7-0.6-0.70.40.40.60.3-0.1-0.20.2
Food seeking constrained by brief footshock0.50.61.50.50.10.40.5-1.2-1.01.00.50.90.70.5-1.21.0
Seeking ratio, punishment vs. effort0.20.20.6-0.5-0.40.8-0.50.30.4-0.4-0.6-0.5-0.5-0.20.1-0.2
Retroperitoneal fat weight2.47.918.2-4.3-3.93.5-3.92.32.9-2.2-2.6-2.7-2.5-1.10.5-1.0
Reaction time number correct5.27.514.8-0.60.7-0.1-0.72.93.3-3.3-3.2-3.0-2.4-3.73.9-3.5
Reaction time mean minus median0.70.91.50.50.1-0.20.7-1.1-0.91.21.10.91.21.1-1.11.1
Reaction time mean minus median AUC0.10.10.60.1-0.00.20.2-0.3-0.10.40.80.20.50.6-0.40.3
Reaction time num false alarms0.10.20.80.60.5-0.90.5-0.5-0.50.3-0.10.40.2-0.2-0.00.2
Reaction time num false alarms AUC0.30.41.61.01.0-1.30.9-0.4-0.50.2-0.00.40.2-0.40.2-0.1
Reaction time trials correct on left5.27.514.8-0.60.7-0.1-0.72.93.3-3.3-3.2-3.0-2.4-3.73.9-3.5
Reaction time trials on left5.47.715.3-0.60.8-0.1-0.63.03.3-3.3-3.2-3.1-2.5-3.83.9-3.6
Reaction time mean0.20.30.9-0.6-0.50.2-0.60.50.7-0.4-1.0-0.6-0.6-0.60.3-0.3
Reaction time mean AUC0.50.71.5-0.6-0.30.1-0.50.81.1-0.8-1.2-1.0-0.8-1.00.9-0.8
Median of all reaction times0.50.71.9-0.7-0.50.2-0.70.81.0-0.8-1.4-0.9-0.9-0.90.7-0.7
Reaction time omissions0.30.41.5-0.3-0.10.0-0.10.60.7-0.7-0.7-0.7-0.6-1.20.8-0.7
Reaction time false alarm rate1.72.34.11.20.5-1.01.1-1.8-2.01.81.61.81.41.5-1.71.7
Reaction time premature initiation rate0.60.82.21.41.2-1.51.1-0.4-1.10.60.21.00.6-0.0-0.20.3
Reaction time premature initiations1.21.74.00.91.5-1.40.61.30.8-1.2-1.6-0.7-0.8-2.01.8-1.6
Std. dev. reaction times0.10.20.60.70.7-0.70.8-0.5-0.10.3-0.20.20.4-0.30.10.0
Reaction time trials completed5.47.715.3-0.60.8-0.1-0.63.03.3-3.3-3.2-3.1-2.5-3.83.9-3.6
Reaction time trials AUC5.47.815.3-0.70.7-0.1-0.73.03.3-3.3-3.2-3.1-2.5-3.83.9-3.6
Run reversals in cocaine runway, females0.70.71.80.60.9-0.70.50.30.6-0.7-1.1-0.4-0.4-1.21.4-0.9
Run reversals in cocaine runway, males0.90.92.2-1.0-1.51.0-0.8-0.4-0.40.80.90.50.51.2-1.11.2
Latency to leave start box in cocaine runway0.10.20.40.50.7-0.60.30.30.1-0.3-0.4-0.1-0.3-0.40.2-0.6
Latency to leave start box in cocaine runway, F0.80.91.80.51.0-0.90.30.90.7-1.0-1.0-0.8-0.8-1.01.3-1.4
Latency to leave start box in cocaine runway, M0.20.20.8-0.2-0.40.4-0.5-0.0-0.20.20.40.1-0.10.4-0.90.3
Std. dev. time between licks in bursts4.35.18.0-1.1-0.00.8-1.12.52.8-2.7-2.8-2.7-2.7-2.62.4-2.7
Total sessions with >9 infusions0.10.10.40.50.6-0.60.4-0.0-0.1-0.10.4-0.0-0.00.20.4-0.3
Short access day 1 total inactive lever presses0.70.82.9-0.00.5-0.3-0.10.90.9-1.1-0.4-0.9-0.9-0.91.7-1.3
Short access day 10 total inactive lever presses1.71.97.1-2.1-2.22.7-2.11.00.8-0.7-0.4-0.7-0.90.4-0.50.1
Short access day 1 total infusions0.91.02.51.51.4-1.31.6-1.1-0.80.80.70.80.90.2-0.10.3
Short access day 10 total infusions0.30.30.8-0.8-0.90.9-0.80.10.5-0.10.1-0.4-0.30.4-0.00.2
Short access total infusions0.00.00.1-0.00.00.2-0.1-0.10.0-0.00.1-0.1-0.10.20.0-0.0
Short access day 1 locomotion0.70.71.60.80.6-0.90.9-0.9-0.81.01.30.80.90.8-0.30.8
Short access day 10 total locomotion0.70.81.50.4-0.0-0.10.5-1.0-1.11.21.21.00.91.0-1.01.2
Short access total locomotion0.70.82.20.80.5-0.50.7-0.9-1.01.01.50.80.81.0-0.70.8
One hour access (0.3 mA shock)1.21.42.8-1.5-1.31.2-1.71.31.2-1.2-1.0-1.3-1.4-0.20.6-0.8
Compulsive drug intake0.50.51.5-0.8-0.61.0-0.60.50.6-0.6-1.2-0.6-0.5-0.7-0.0-0.4
One hour access (shock baseline)0.40.50.9-0.5-0.20.1-0.70.80.8-0.80.1-0.8-0.9-0.10.9-0.8
Social response proportion0.20.20.60.60.8-0.70.50.10.1-0.3-0.2-0.1-0.1-0.70.6-0.5
Social responses0.10.20.50.40.6-0.20.5-0.10.3-0.2-0.1-0.3-0.5-0.70.0-0.5
Social time0.10.10.40.30.5-0.50.50.30.4-0.3-0.1-0.20.1-0.60.1-0.5
Soleus weight0.82.45.7-2.2-1.92.4-2.11.31.6-1.4-0.9-1.6-1.3-0.20.4-0.8
Bone: stiffness0.50.81.7-1.3-1.11.3-1.01.10.9-0.9-0.6-1.0-0.9-0.30.0-0.5
Tibialis anterior weight0.20.81.4-0.40.10.9-0.41.01.1-1.1-0.5-1.1-1.1-0.60.9-1.2
Time to tail flick, vehicle, before self-admin0.20.20.8-0.3-0.10.7-0.40.30.5-0.40.3-0.5-0.4-0.10.9-0.4
Time to tail flick, vehicle, after self-admin1.11.23.51.71.8-1.91.7-0.7-0.60.50.80.70.90.3-0.3-0.1
Time to tail flick, test, before self-admin0.20.20.5-0.2-0.40.7-0.50.2-0.60.10.20.2-0.00.7-0.30.3
Time to tail flick, test, after self-admin0.30.30.60.70.6-0.40.8-0.6-0.50.50.80.50.60.20.10.3
Delta time to tail flick, vehicle, before/after SA0.30.31.10.60.9-1.00.70.40.2-0.4-0.6-0.2-0.1-0.60.1-0.7
Delta time to tail flick, test, before/after SA0.80.81.60.90.6-1.31.1-1.0-0.61.00.90.91.10.4-0.30.7
Tibia length3.29.032.9-5.1-5.74.3-4.71.50.8-0.40.1-0.8-0.42.5-2.41.4
Ambulatory time before self-admin1.01.13.8-1.6-2.01.9-1.1-0.30.30.40.1-0.00.10.5-1.01.0
Ambulatory time after self-admin0.30.30.5-0.7-0.50.7-0.50.50.7-0.6-0.7-0.6-0.3-0.60.5-0.4
Bone: tissue strength1.61.62.4-1.3-0.91.2-1.11.51.5-1.4-1.3-1.5-1.6-1.00.6-1.1
Total heroin consumption1.11.23.40.1-0.40.20.8-1.5-1.11.50.51.21.80.4-1.51.6
Bone: trabecular number0.00.00.2-0.1-0.0-0.0-0.10.50.2-0.2-0.1-0.2-0.30.2-0.0-0.2
Bone: trabecular spacing3.03.98.0-0.70.20.6-0.52.02.3-2.3-2.4-2.3-2.2-2.82.3-2.4
Bone: trabecular thickness1.51.84.8-0.4-1.10.2-0.4-1.0-1.51.51.21.41.01.9-2.21.9
Bone: trabecular tissue density0.40.61.41.21.1-1.01.1-0.7-0.60.60.40.60.8-0.00.20.2
Water consumed over 24 hours0.81.01.80.3-0.10.60.3-1.2-1.01.11.31.11.11.1-1.11.1
Number of responses in last shaping day0.60.61.0-1.0-0.81.0-0.90.60.9-0.7-0.8-0.8-0.8-0.50.5-0.5