Hub : Genes

Lsm2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression Lsm2 0.18 0.14 9.1e-03 0.04 0.05 0 0.04 4.7e-02 2.1e-02 2.4e-01 3.5e-02
2 Liver intron excision ratio chr20_3848861_3851065 0.28 0.1 0.0e+00 0.08 0.12 0.1 0.11 1.7e-09 4.9e-13 1.0e-10 2.6e-12
3 Liver intron excision ratio chr20_3851132_3851663 0.27 0.1 2.2e-16 0.08 0.11 0.09 0.1 1.4e-09 2.8e-12 1.5e-10 3.5e-11
4 NAcc intron excision ratio chr20_3848861_3851065 0.06 0.04 3.6e-07 0.03 0.04 0.03 0.03 3.0e-05 1.2e-06 7.6e-05 1.6e-05
5 BLA gene expression Lsm2 0.17 0.12 6.7e-04 0.07 0.04 0.07 0.07 1.1e-04 3.4e-03 1.3e-04 1.7e-04
6 NAcc intron excision ratio chr20_3851132_3851663 0.05 0.03 5.2e-06 0.03 0.03 0.02 0.02 3.5e-05 1.4e-05 2.3e-04 2.1e-04
7 PL gene expression Lsm2 0.13 0.07 1.3e-08 0.09 0.08 0.08 0.09 3.4e-10 2.8e-09 9.3e-09 4.5e-10
8 Adipose gene expression Lsm2 0.05 0.03 5.2e-05 0.05 0.04 0.04 0.04 4.7e-06 3.7e-05 5.7e-05 1.3e-05
9 IC gene expression Lsm2 0.11 0.07 2.0e-03 0.02 0.03 0.01 0.02 4.0e-02 2.6e-02 1.1e-01 6.4e-02
10 NAcc gene expression Lsm2 0.09 0.04 2.1e-12 0.09 0.08 0.08 0.08 1.9e-13 8.5e-12 7.0e-12 2.5e-12
11 Liver gene expression Lsm2 0.05 0.03 4.5e-04 0.01 0.02 0 0.01 2.4e-02 1.8e-03 1.4e-01 8.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.50.93.70.1-1.91.9-0.7-0.30.7-0.3-0.20.8-0.2-0.6
Area under the delay curve0.40.51.50.21.0-0.90.61.2-0.60.60.60.10.60.8
BMI with tail2.37.810.6-2.6-2.32.4-2.9-3.22.9-3.0-3.0-2.7-3.3-2.1
BMI without tail1.85.410.1-3.0-0.70.8-2.4-2.62.4-2.6-2.6-3.2-2.80.1
Body weight1.77.716.2-2.9-0.30.4-2.3-3.32.4-3.3-3.3-4.0-3.5-1.9
Weight adjusted by age0.91.34.0-1.30.3-0.4-0.9-0.70.9-1.4-1.4-2.0-1.4-0.8
Bone surface0.00.00.20.20.2-0.20.2-0.2-0.2-0.00.0-0.00.0-0.5
Bone volume0.20.30.6-0.3-0.80.8-0.6-0.70.6-0.5-0.5-0.2-0.5-0.5
Breakpoint value in progressive ratio session0.40.50.90.60.6-0.60.70.8-0.70.90.90.70.80.4
Number of licking bursts1.52.53.61.71.8-1.81.91.3-1.91.71.71.21.60.1
Context. condit. distance diff. score3.34.08.62.90.8-0.82.22.0-2.22.22.12.62.0-1.2
Locomotion velocity, session 11.51.62.81.21.0-1.11.31.7-1.31.41.41.21.21.0
Locomotion distance, session 10.30.31.00.5-1.00.9-0.00.4-0.00.40.41.00.3-0.2
Locomotion velocity, session 21.01.21.61.20.8-0.81.21.2-1.21.31.21.11.20.4
Locomotion distance, session 20.50.71.61.1-0.70.70.50.8-0.50.70.71.30.5-1.0
Locomotion velocity, session 30.20.21.1-0.6-0.20.1-0.4-0.10.4-0.00.0-0.2-0.41.0
Locomotion distance, session 30.70.82.31.0-0.50.40.51.0-0.61.01.11.50.90.4
Stereotopy head waving bouts, day 30.60.72.90.31.7-1.70.90.3-0.80.40.4-0.40.30.1
Stereotopy head waving duration, day 30.50.62.2-0.31.5-1.50.40.2-0.30.00.0-0.80.10.8
Locomotion velocity, session 71.51.74.71.7-1.41.40.51.4-0.61.01.02.20.9-1.2
Locomotion distance, session 71.92.47.31.9-1.00.91.01.9-1.11.61.72.71.6-0.1
Stereotopy head waving bouts, day 71.31.55.00.11.7-1.70.91.0-0.91.01.10.21.02.2
Stereotopy head waving duration, day 70.50.62.5-0.31.2-1.20.40.4-0.40.50.5-0.30.41.6
Locomotion velocity, session 84.75.77.92.72.6-2.62.82.3-2.82.42.51.82.2-0.0
Locomotion distance, session 82.63.89.43.10.0-0.01.91.8-2.01.91.92.81.6-2.1
Degree of sensitization distance0.60.61.01.00.9-0.81.00.7-1.00.70.60.60.7-0.5
Degree of sensitization stereotypy1.21.34.20.31.1-1.10.91.1-0.91.21.20.71.12.1
Conditioned locomotion0.40.41.7-0.20.1-0.1-0.2-0.80.3-0.7-0.7-0.8-0.6-1.3
Cocaine response after cond. corrected0.50.64.40.7-0.70.80.0-0.5-0.0-0.2-0.20.4-0.1-2.1
Cocaine response after cond. not corrected0.30.41.20.70.8-0.80.7-0.1-0.60.20.2-0.00.2-1.1
Cocaine response before conditioning1.51.86.3-0.72.5-2.50.70.2-0.60.30.3-1.30.11.9
Saline control response3.24.28.8-3.0-0.80.8-2.2-2.12.3-2.3-2.3-2.5-1.91.3
Bone: connectivity density0.60.93.00.2-1.71.7-0.6-0.60.6-0.6-0.50.6-0.3-1.4
Bone: cortical apparent density2.02.73.6-1.8-1.51.6-1.8-1.91.8-1.8-1.7-1.5-1.7-0.5
Bone: cortical area0.10.10.50.10.7-0.70.40.0-0.30.20.3-0.30.00.0
Bone: cortical porosity2.72.910.00.21.9-2.01.22.0-1.21.51.60.51.53.2
Bone: cortical porosity3.13.38.00.62.2-2.31.52.2-1.51.61.60.71.72.8
Bone: cortical thickness0.61.01.7-1.3-1.01.1-1.2-1.11.2-0.9-0.8-0.9-1.00.3
Bone: cortical thickness1.92.33.0-1.7-1.51.5-1.7-1.71.7-1.5-1.5-1.3-1.60.1
Bone: cortical tissue density1.82.53.2-1.7-1.41.4-1.7-1.81.8-1.7-1.7-1.5-1.7-0.5
Condit. Reinf. active minus inactive responses1.21.33.30.70.5-0.60.91.8-0.91.31.31.11.11.5
Condit. Reinf. active-inactive response ratio0.20.21.5-0.50.1-0.1-0.20.40.20.10.1-0.2-0.01.2
Condit. Reinf. active responses0.40.51.80.5-0.40.30.41.4-0.40.80.81.10.60.7
Condit. Reinf. inactive responses0.50.62.60.4-1.61.6-0.30.40.30.20.21.10.1-0.3
Incentive salience index mean2.32.85.42.00.8-0.81.72.3-1.81.91.92.01.70.2
Condit. Reinf. lever presses2.43.37.72.80.5-0.51.91.9-2.01.71.72.41.7-1.6
Condit. Reinf. active minus inactive responses0.20.30.9-0.50.9-1.00.00.1-0.0-0.1-0.1-0.7-0.20.9
Condit. Reinf. active-inactive response ratio0.40.52.1-0.21.4-1.40.40.2-0.40.00.1-0.60.10.7
Condit. Reinf. active responses0.10.10.6-0.50.3-0.4-0.2-0.10.2-0.1-0.0-0.4-0.20.8
Condit. Reinf. inactive responses0.20.30.5-0.6-0.70.7-0.7-0.60.7-0.3-0.3-0.3-0.50.2
Condit. Reinf. lever presses0.20.31.50.10.2-0.30.20.7-0.30.50.50.50.51.2
Condit. Reinf. lever reinforcers received0.20.21.1-0.20.6-0.70.20.3-0.20.30.3-0.10.21.1
Conditioned reinforcement - actives0.20.40.8-0.6-0.90.8-0.8-0.30.7-0.6-0.6-0.3-0.6-0.0
Conditioned reinforcement - inactives0.20.30.6-0.7-0.80.7-0.80.20.7-0.5-0.5-0.4-0.50.3
Conditioned locomotion0.10.10.2-0.1-0.30.3-0.20.20.2-0.4-0.4-0.1-0.4-0.1
Patch foraging indifference point 0 sec1.62.95.5-2.3-0.90.9-1.9-1.61.9-2.0-2.0-2.0-1.70.7
Patch foraging indifference point AUC0.60.92.10.21.4-1.30.80.8-0.80.70.70.21.01.4
Delay disc. indifference point, 0s delay0.40.50.80.80.6-0.60.80.9-0.80.70.70.50.7-0.5
Delay disc. indifference point, 16s delay0.10.10.7-0.6-0.10.2-0.30.40.3-0.2-0.2-0.2-0.20.8
Delay disc. indifference point, 2s delay1.21.33.10.41.7-1.81.11.5-1.11.01.00.11.00.8
Delay disc. indifference point, 24s delay0.40.52.1-0.40.8-0.80.21.1-0.20.10.1-0.40.11.4
Delay disc. indifference point, 4s delay0.40.51.5-0.31.2-1.20.40.5-0.30.30.3-0.60.30.8
Delay disc. indifference point, 8s delay0.40.41.60.40.6-0.60.61.2-0.60.60.60.40.60.6
Indifference point function ln k0.81.52.11.21.2-1.21.31.5-1.31.41.51.01.10.4
Indifference point function log k0.81.52.11.21.2-1.21.31.5-1.31.41.51.01.10.4
Patch foraging total patch changes 0 sec1.63.05.9-2.4-1.01.0-1.9-1.61.9-2.0-2.0-2.1-1.70.8
Patch foraging total patch changes 12 sec1.11.43.0-1.7-0.40.4-1.2-1.21.3-1.3-1.3-1.5-0.91.0
Patch foraging total patch changes 18 sec2.94.45.8-2.3-2.12.2-2.3-2.32.3-2.4-2.4-1.7-1.9-0.1
Patch foraging total patch changes 24 sec1.11.83.8-1.4-2.02.0-1.6-1.01.6-1.3-1.3-0.5-0.90.3
Patch foraging total patch changes 6 sec1.72.64.6-2.1-1.01.1-1.8-1.51.8-1.9-1.9-1.7-1.50.7
Patch foraging time to switch 0 sec2.24.56.2-1.3-2.52.5-2.1-2.42.0-2.1-2.1-1.2-2.2-2.5
Patch foraging water rate 0 sec0.00.10.2-0.30.4-0.3-0.00.20.0-0.2-0.3-0.5-0.20.2
Patch foraging water rate 12 sec0.10.20.5-0.4-0.70.7-0.5-0.20.4-0.1-0.10.0-0.20.3
Patch foraging water rate 18 sec0.10.20.5-0.7-0.30.3-0.5-0.30.6-0.4-0.4-0.6-0.60.1
Patch foraging water rate 24 sec0.20.20.5-0.6-0.40.4-0.6-0.70.6-0.4-0.3-0.5-0.50.1
Patch foraging water rate 6 sec0.00.10.1-0.4-0.30.4-0.3-0.30.3-0.1-0.1-0.2-0.20.1
Seeking ratio, delayed vs. immediate footshock0.60.72.6-0.61.3-1.30.3-0.6-0.20.30.3-0.70.41.6
Distance traveled before self-admin0.40.52.50.1-0.30.3-0.3-1.20.3-0.6-0.6-0.5-0.6-1.6
Distance traveled after self-admin0.40.51.5-0.70.8-0.7-0.2-1.10.3-0.5-0.5-1.2-0.4-0.0
Extensor digitorum longus weight0.00.20.70.50.5-0.50.4-0.1-0.4-0.00.0-0.1-0.1-0.9
Bone: elastic displacement0.20.21.5-0.6-0.40.4-0.40.30.4-0.1-0.10.00.01.2
Bone: elastic work0.10.10.3-0.5-0.00.0-0.30.10.3-0.3-0.3-0.4-0.30.4
Bone: endosteal estimation0.81.98.10.32.8-2.81.10.0-1.00.10.2-1.2-0.0-0.5
Bone: endosteal perimeter1.22.56.41.62.5-2.51.90.9-1.81.11.10.20.9-0.8
Epididymis fat weight8.830.139.0-5.5-6.26.2-6.2-5.56.2-5.5-5.5-4.2-5.8-2.0
Delta time in closed arm before/after self-admin0.50.51.2-0.5-0.40.4-0.6-0.80.6-0.8-0.8-0.8-0.7-1.1
Delta time in open arm before/after self-admin0.30.30.5-0.7-0.60.5-0.7-0.30.6-0.4-0.4-0.3-0.50.5
Diff in mean of infusions in LGA sessions0.81.02.91.6-0.30.41.00.6-1.01.01.01.70.7-0.9
Delay discount exponential model param0.60.61.7-0.1-1.11.1-0.6-1.30.6-0.7-0.7-0.0-0.7-1.0
Extinction: sum of active levers before priming0.80.91.31.10.9-0.81.11.0-1.11.01.00.81.0-0.3
Active lever presses in extinction session 60.40.41.1-0.5-1.11.0-0.70.40.7-0.4-0.4-0.1-0.40.1
Bone: final force1.72.84.5-1.7-0.91.0-1.6-2.11.7-1.9-1.9-2.0-2.0-1.1
Bone: final moment1.52.43.5-1.6-0.90.9-1.5-1.91.6-1.8-1.8-1.9-1.8-0.9
Food consumed during 24 hour testing period0.30.53.10.10.1-0.0-0.1-0.70.1-0.5-0.5-0.6-0.6-1.8
Glucose4.16.48.92.82.9-3.03.02.6-3.02.42.51.82.3-0.3
Heart weight0.50.72.1-0.91.4-1.4-0.00.10.1-0.4-0.4-1.4-0.41.0
Delay discount hyperbolic model param0.80.92.0-0.1-1.21.3-0.7-1.40.7-0.8-0.8-0.0-0.8-1.2
Intermittent access intake day 1-15 change0.10.10.60.00.4-0.40.3-0.2-0.20.20.20.10.20.8
Intermittent access intake escalation0.10.22.0-0.60.10.0-0.2-0.40.2-0.1-0.1-0.2-0.11.4
Intermittent access intake escalation 20.40.51.00.40.8-0.70.70.4-0.70.80.80.40.81.0
Intermitt. access day 1 inactive lever presses0.20.81.81.11.0-1.01.00.4-0.90.80.80.30.8-1.3
Intermitt. access day 15 inactive lever presses0.10.20.5-0.40.1-0.1-0.3-0.30.3-0.5-0.5-0.7-0.5-0.3
Intermitt. access escalation Index1.01.52.91.70.3-0.21.30.8-1.31.41.41.71.4-0.8
Intermittent access day 1 total infusions0.30.41.30.4-1.00.9-0.11.20.00.30.31.00.30.4
Intermittent access day 15 total infusions0.20.31.4-0.4-0.70.7-0.40.30.3-0.0-0.00.3-0.01.2
Intermittent access terminal intake (last 3 days)0.20.21.7-0.5-0.40.3-0.40.40.4-0.1-0.1-0.0-0.01.3
Intermittent access total infusions0.20.30.8-0.4-0.80.7-0.50.60.4-0.2-0.20.2-0.20.9
Intermittent access day 1 locomotion0.50.61.5-0.4-1.21.2-0.8-0.40.8-0.8-0.8-0.1-0.8-0.4
Intermittent access day 15 total locomotion0.30.61.1-0.8-0.20.3-0.6-0.90.7-1.0-1.0-0.9-1.0-0.1
Intermittent access total locomotion0.60.70.9-0.9-0.80.8-0.9-0.50.9-1.0-1.0-0.6-1.00.2
Intermittent access standard deviation1.22.64.1-2.0-0.90.9-1.7-1.71.7-1.8-1.8-2.0-1.80.1
Left kidney weight1.88.116.2-3.4-0.70.7-2.7-3.22.8-3.3-3.3-4.0-3.5-0.9
Right kidney weight1.98.615.8-3.2-0.91.0-2.8-3.42.8-3.5-3.4-4.0-3.5-1.7
Cocaine induced anxiety0.20.30.70.70.4-0.40.60.1-0.50.40.40.30.4-0.9
Post-drug Anxiety0.10.10.3-0.00.3-0.30.0-0.4-0.0-0.0-0.0-0.3-0.0-0.5
Baseline Anxiety0.10.10.2-0.40.1-0.1-0.2-0.40.3-0.3-0.3-0.5-0.30.2
Tail length0.72.711.5-0.53.4-3.41.00.2-0.90.10.1-1.8-0.01.4
Length with tail0.52.27.1-0.92.7-2.60.3-0.6-0.2-0.8-0.8-2.5-1.0-0.3
Length without tail1.34.19.9-1.30.1-0.1-1.2-2.21.3-2.4-2.2-2.9-2.5-3.2
Times rat made contact with spout0.50.53.6-0.4-0.60.6-0.20.60.20.50.50.60.31.9
Lifetime Intake0.20.30.6-0.5-0.80.6-0.50.60.5-0.2-0.20.1-0.20.8
Liver weight, left0.50.82.60.51.6-1.60.8-0.5-0.70.00.1-0.6-0.1-1.2
Liver weight, right0.81.34.01.02.0-2.01.30.7-1.30.60.7-0.20.6-0.7
Locomotor activity0.60.93.2-0.11.8-1.80.70.2-0.60.50.5-0.60.51.1
Locomotor testing distance0.10.21.0-0.01.0-1.00.3-0.1-0.30.10.1-0.50.10.1
Locomotor testing rearing0.20.41.0-0.50.2-0.2-0.4-0.90.4-0.8-0.7-1.0-0.8-0.8
Locomotion in novel chamber0.00.00.3-0.3-0.10.1-0.2-0.50.20.00.1-0.20.10.0
Locomotion in novel chamber post-restriction1.01.62.5-1.4-0.70.7-1.3-1.41.3-1.5-1.5-1.6-1.5-0.6
Fecal boli incidents, locomotor time 10.71.02.4-0.6-1.61.4-1.1-0.31.0-0.9-0.9-0.3-0.8-1.0
Change in fecal boli incidents, locomotor task1.21.13.60.91.9-1.81.30.2-1.20.70.6-0.00.8-0.3
Time >=10cm from walls, locomotor time 11.01.14.5-0.40.4-0.3-0.4-1.40.4-0.9-0.9-1.4-1.0-2.1
Bouts of movement, locomotor time 10.60.61.10.90.4-0.40.90.7-0.80.91.11.00.90.3
Total resting periods, locomotor time 10.50.50.90.90.5-0.40.80.6-0.80.80.90.90.80.2
Rest time, locomotor task time 10.10.10.30.20.4-0.40.20.6-0.30.40.30.10.40.2
Distance moved, locomotor task time 10.10.10.3-0.40.2-0.1-0.2-0.40.3-0.5-0.5-0.6-0.5-0.0
Vertical activity count, locomotor time 10.30.71.3-1.0-0.40.5-0.8-1.10.8-1.0-1.0-1.0-0.9-0.4
Time >=10cm from walls, locomotor time 20.30.51.3-0.30.9-0.90.1-0.4-0.0-0.7-0.7-1.1-0.6-1.1
Bouts of movement, locomotor time 20.50.81.70.21.2-1.20.80.6-0.81.01.00.31.01.3
Total resting periods, locomotor time 21.11.93.10.61.7-1.81.31.2-1.31.51.50.61.51.6
Rest time, locomotor task time 20.70.91.81.30.8-0.71.10.4-1.10.90.90.70.9-1.3
Distance moved, locomotor task time 21.51.73.0-1.3-1.11.1-1.4-0.91.4-1.7-1.7-1.3-1.7-0.3
Vertical activity count, locomotor time 20.81.11.9-1.1-0.70.7-1.1-0.81.1-1.4-1.3-1.2-1.3-0.5
Light reinforcement 10.51.22.9-0.5-0.70.8-0.7-1.70.8-1.3-1.3-0.9-1.2-1.6
Light reinforcement 20.40.73.0-0.1-0.40.5-0.4-1.00.4-0.7-0.7-0.6-1.1-1.7
Bone: marrow area0.81.77.60.12.8-2.81.0-0.2-0.9-0.0-0.0-1.4-0.2-0.5
Bone: maximum diameter1.62.94.91.82.2-2.22.11.5-2.01.71.70.91.4-0.2
Bone: maximum force0.91.62.6-1.3-0.60.6-1.2-1.51.2-1.4-1.4-1.6-1.6-1.0
Bone: maximum moment0.71.22.2-1.2-0.50.5-1.1-1.21.1-1.3-1.3-1.5-1.4-0.8
Mean time between licks in bursts1.33.24.42.01.9-1.92.11.7-2.11.81.81.51.90.1
Mean num. licks in bursts1.52.33.7-1.9-1.91.9-1.9-1.01.8-1.3-1.3-0.9-1.41.0
Cd content in liver2.12.44.6-0.8-2.22.1-1.5-1.11.5-1.5-1.6-0.6-1.5-1.7
Co content in liver2.52.94.0-1.7-1.41.4-1.7-2.01.8-1.9-1.9-1.7-2.0-0.9
Cu content in liver0.40.51.6-0.2-0.90.9-0.30.70.30.70.70.70.31.3
Fe content in liver1.72.12.7-1.5-1.41.4-1.6-1.41.6-1.6-1.6-1.3-1.3-0.5
K content in liver0.40.30.90.8-0.20.20.50.4-0.50.70.70.90.6-0.3
Mg content in liver2.72.84.92.21.3-1.31.91.3-1.91.81.81.71.6-0.5
Mn content in liver2.32.64.82.21.6-1.62.01.6-1.91.41.41.31.1-1.3
Na content in liver0.40.41.30.20.4-0.40.40.6-0.40.70.80.50.91.2
Rb content in liver0.30.41.80.3-0.80.8-0.3-0.70.2-0.5-0.50.2-0.2-1.3
Se content in liver6.37.510.52.62.9-2.93.02.6-3.03.23.22.12.61.3
Sr content in liver0.30.30.9-0.3-0.00.0-0.3-0.00.3-0.8-1.0-0.6-0.7-0.5
Zn content in liver0.10.10.30.40.1-0.10.20.1-0.20.10.10.20.0-0.6
Bone: minimum diameter0.71.33.71.11.9-1.91.40.5-1.30.70.7-0.00.5-0.9
Time in familiar zone, hab. session 10.80.82.5-0.6-1.61.5-0.90.00.8-0.2-0.20.5-0.01.2
Time in novel zone, hab. session 10.50.52.00.11.4-1.40.5-0.3-0.4-0.1-0.1-0.9-0.2-0.7
Total zone transitions, hab. session 10.20.30.70.80.2-0.10.60.3-0.60.70.70.80.7-0.1
Total locomotion distance, hab. session 10.20.20.60.7-0.30.30.30.2-0.30.40.40.80.4-0.5
Locomotion velocity, hab. session 10.10.20.50.6-0.10.10.40.2-0.40.40.50.70.4-0.2
Time in familiar zone, hab. session 20.30.30.9-0.7-0.60.6-0.6-1.00.6-0.3-0.3-0.4-0.40.4
Time in novel zone, hab. session 20.00.00.2-0.10.2-0.3-0.00.40.0-0.2-0.2-0.20.00.2
Total zone transitions, hab. session 20.20.21.20.3-0.50.5-0.1-0.70.1-0.2-0.20.2-0.1-1.1
Total locomotion distance, hab. session 20.40.52.40.8-1.01.00.1-0.4-0.10.10.10.90.3-1.5
Locomotion velocity, hab. session 20.50.72.01.2-0.70.70.50.1-0.50.50.51.20.6-1.4
Novel to familiar place preference ratio0.20.20.50.30.3-0.30.40.7-0.40.50.50.50.70.7
Novelty place preference0.40.40.80.30.6-0.60.50.8-0.50.60.60.40.80.9
Time in novel zone, NPP test0.40.41.10.20.7-0.70.50.7-0.50.50.50.30.81.1
Total zone transitions, NPP test0.40.61.61.1-0.70.70.40.3-0.40.60.61.30.6-0.9
Total locomotion distance, NPP test0.71.03.40.7-1.71.7-0.4-0.00.3-0.2-0.20.9-0.2-1.9
Locomotion velocity, NPP test0.91.24.31.0-1.81.8-0.20.10.1-0.0-0.01.30.0-2.1
Intraocular pressure0.71.02.1-0.6-1.41.4-1.0-1.21.0-1.0-1.0-0.2-0.9-0.3
Delta distance traveled before/after self-admin0.70.83.7-0.91.2-1.30.00.4-0.00.20.1-0.90.21.9
Delta ambulatory time before/after self-admin0.60.82.7-0.51.4-1.50.30.4-0.30.30.3-0.70.41.6
Parametrial fat weight3.17.310.3-2.2-2.52.6-2.7-3.22.7-3.0-3.0-2.3-3.2-2.2
Pavlov. Cond. lever latency5.87.410.1-3.2-2.02.1-3.0-3.23.0-2.9-2.9-3.0-2.9-0.6
Pavlov. Cond. magazine entry latency5.16.67.92.32.5-2.52.72.8-2.72.82.82.32.81.9
Pavlov. Cond. change in total contacts3.23.44.11.61.9-1.92.02.0-2.02.02.01.51.91.4
Pavlov. Cond. index score6.68.310.23.12.5-2.53.23.2-3.23.13.12.93.11.1
Pavlov. Cond. latency score7.08.811.03.22.6-2.63.33.2-3.33.23.23.03.21.1
Pavlov. Cond. lever contacts4.55.48.83.01.7-1.72.62.6-2.62.42.32.62.5-0.2
Pavlov. Cond. magazine entry number3.34.15.1-1.9-1.91.9-2.2-2.22.2-2.3-2.2-1.8-2.2-1.4
Pavlov. Cond. intertrial magazine entries2.73.36.3-1.5-2.52.5-2.1-1.52.0-1.7-1.6-0.9-1.8-0.9
Pavlov. Cond. lever-magazine prob. diff.6.47.910.13.12.3-2.33.13.2-3.13.13.12.93.01.1
Pavlov. Cond. response bias4.55.67.42.62.0-2.02.62.7-2.62.62.62.42.50.9
Pavlov. Cond. lever latency0.20.21.50.60.5-0.40.4-0.2-0.4-0.0-0.0-0.10.0-1.2
Pavlov. Cond. magazine entry latency0.20.20.40.50.3-0.30.50.6-0.50.40.40.50.50.3
Pavlov. Cond. change in total contacts0.20.32.2-0.50.2-0.3-0.10.30.10.10.1-0.10.21.5
Pavlov. Cond. index score0.10.21.1-0.00.2-0.30.20.6-0.20.30.40.30.41.0
Pavlov. Cond. latency score0.10.11.0-0.20.1-0.1-0.00.40.00.10.20.10.21.0
Pavlov. Cond. lever contacts0.10.21.1-0.6-0.40.4-0.50.10.4-0.1-0.1-0.1-0.11.0
Pavlov. Cond. magazine entry number0.00.00.1-0.10.3-0.30.1-0.0-0.10.10.1-0.1-0.00.1
Pavlov. Cond. intertrial magazine entries1.42.02.61.41.5-1.51.61.3-1.61.61.61.21.50.5
Pavlov. Cond. lever-magazine prob. diff.0.10.10.8-0.10.1-0.10.10.5-0.10.20.30.20.30.9
Pavlov. Cond. response bias0.20.20.90.2-0.0-0.00.20.7-0.20.50.50.50.50.9
Time in closed arm before self-admin0.10.20.60.20.8-0.70.40.2-0.40.20.2-0.00.10.2
Time in closed arm after self-admin0.10.10.2-0.2-0.20.1-0.2-0.40.2-0.3-0.3-0.3-0.3-0.4
Time in open arm before self-admin1.31.42.20.91.0-1.01.11.5-1.11.31.31.11.31.4
Time in open arm after self-admin0.20.21.4-0.10.3-0.40.10.7-0.20.40.40.20.41.2
Bone: periosteal estimation0.51.04.6-0.02.1-2.10.7-0.2-0.60.00.1-1.2-0.2-0.2
Bone: periosteal perimeter0.81.44.00.92.0-1.91.40.9-1.30.90.90.10.8-0.0
Bone: post-yield work0.30.41.90.70.8-0.80.6-0.2-0.6-0.00.1-0.10.0-1.4
Progressive ratio test 1 active lever presses0.10.10.2-0.1-0.50.4-0.30.40.3-0.2-0.20.0-0.20.0
Progressive ratio test 1 breakpoint0.10.10.2-0.1-0.40.4-0.30.40.2-0.2-0.20.0-0.20.0
Progressive ratio test 1 inactive lever presses0.91.32.6-0.7-1.61.6-1.2-1.01.2-1.1-1.1-0.5-1.1-1.0
Progressive ratio test 2 active lever presses0.10.20.50.2-0.70.7-0.10.40.10.20.20.60.20.4
Progressive ratio test 2 breakpoint0.20.20.50.1-0.70.7-0.10.40.10.20.20.60.20.5
Progressive ratio test 2 inactive lever presses0.10.20.90.6-0.10.10.30.9-0.30.40.40.60.4-0.2
Incentive Sensitization - Responses0.40.61.00.70.1-0.10.60.6-0.61.01.01.01.00.8
Incentive Sensitization - Breakpoint0.30.40.90.6-0.10.10.40.4-0.50.80.80.90.80.6
Sum of active levers in priming session hrs 5-60.30.31.20.30.4-0.50.41.1-0.50.60.50.40.40.6
Progressive ratio2.54.07.9-2.6-0.30.4-1.9-2.82.0-2.2-2.2-2.8-2.00.0
Food seeking constrained by brief footshock0.10.20.5-0.5-0.40.4-0.50.10.4-0.3-0.3-0.2-0.10.7
Seeking ratio, punishment vs. effort2.33.36.82.10.7-0.71.72.6-1.82.02.02.32.00.7
Retroperitoneal fat weight0.41.83.1-0.8-1.71.7-1.3-1.21.3-1.2-1.2-0.7-1.6-1.5
Reaction time number correct1.53.04.2-2.1-1.41.4-1.9-1.62.0-1.9-1.9-1.8-2.0-0.0
Reaction time mean minus median1.02.64.02.01.1-1.11.81.7-1.81.81.81.81.80.0
Reaction time mean minus median AUC0.92.23.81.90.5-0.61.51.9-1.61.61.61.91.5-0.1
Reaction time num false alarms1.01.42.11.11.4-1.41.30.9-1.31.21.30.81.20.6
Reaction time num false alarms AUC1.42.24.01.12.0-1.91.61.1-1.61.51.50.71.51.0
Reaction time trials correct on left1.53.04.2-2.1-1.41.4-1.9-1.62.0-1.9-1.9-1.8-2.0-0.0
Reaction time trials on left1.52.94.1-2.0-1.31.3-1.9-1.61.9-1.9-1.8-1.8-2.0-0.0
Reaction time mean1.32.14.82.20.7-0.71.61.4-1.61.31.31.71.3-1.4
Reaction time mean AUC1.22.04.52.10.6-0.61.51.4-1.61.31.31.71.2-1.3
Median of all reaction times0.81.12.91.70.3-0.31.10.9-1.10.80.81.20.7-1.6
Reaction time omissions0.91.32.71.70.7-0.71.30.9-1.31.11.11.21.1-1.0
Reaction time false alarm rate4.05.57.22.22.7-2.62.62.1-2.62.52.51.72.61.0
Reaction time premature initiation rate0.50.71.2-0.7-0.50.4-0.8-0.80.8-1.1-1.0-0.9-1.0-0.8
Reaction time premature initiations1.73.04.5-1.9-1.11.0-1.8-1.71.8-2.1-2.0-2.0-2.1-0.7
Std. dev. reaction times2.24.15.52.41.8-1.82.32.2-2.32.22.22.02.20.2
Reaction time trials completed1.52.94.1-2.0-1.31.3-1.9-1.61.9-1.9-1.8-1.8-2.0-0.0
Reaction time trials AUC1.52.94.0-2.0-1.41.4-1.9-1.71.9-1.9-1.9-1.8-2.0-0.2
Run reversals in cocaine runway, females1.01.01.6-0.9-1.31.2-1.2-0.81.1-1.2-1.2-0.6-1.0-0.3
Run reversals in cocaine runway, males0.50.50.80.90.6-0.60.80.7-0.80.70.70.70.7-0.1
Latency to leave start box in cocaine runway0.91.11.91.40.6-0.71.11.0-1.11.11.01.11.1-0.9
Latency to leave start box in cocaine runway, F0.60.71.31.10.3-0.30.80.9-0.80.90.91.01.0-0.7
Latency to leave start box in cocaine runway, M0.20.20.40.50.5-0.50.50.2-0.50.40.20.20.4-0.6
Std. dev. time between licks in bursts2.43.36.11.92.5-2.42.21.4-2.21.61.61.01.7-0.1
Total sessions with >9 infusions0.10.21.2-0.4-0.20.1-0.20.70.2-0.0-0.00.0-0.01.1
Short access day 1 total inactive lever presses0.20.31.70.50.3-0.40.41.3-0.50.50.50.40.5-0.1
Short access day 10 total inactive lever presses0.20.41.00.90.00.00.6-0.1-0.60.60.60.70.6-1.0
Short access day 1 total infusions0.20.31.90.2-0.1-0.00.11.4-0.20.30.30.50.30.6
Short access day 10 total infusions0.20.31.0-0.3-1.00.9-0.50.30.5-0.2-0.20.2-0.20.3
Short access total infusions0.20.20.8-0.2-0.70.6-0.40.90.3-0.1-0.10.2-0.10.5
Short access day 1 locomotion0.50.61.41.10.1-0.10.80.6-0.80.90.91.20.9-0.1
Short access day 10 total locomotion0.30.62.5-0.11.6-1.50.5-0.4-0.4-0.1-0.1-1.0-0.10.0
Short access total locomotion0.10.10.20.20.5-0.50.20.0-0.2-0.1-0.1-0.2-0.1-0.4
One hour access (0.3 mA shock)0.91.12.81.3-0.00.11.00.7-1.01.31.31.71.30.2
Compulsive drug intake2.63.16.32.51.4-1.22.10.4-2.01.81.81.71.8-1.7
One hour access (shock baseline)0.50.81.9-0.9-1.41.3-1.00.11.0-0.6-0.6-0.1-0.61.2
Social response proportion0.20.20.8-0.10.8-0.90.20.3-0.20.0-0.0-0.7-0.2-0.3
Social responses0.30.41.3-0.11.1-1.10.40.5-0.30.40.4-0.50.20.5
Social time2.33.14.62.11.8-1.72.11.2-2.01.91.91.41.8-0.9
Soleus weight1.44.19.82.33.1-3.02.51.0-2.51.21.20.61.3-1.5
Bone: stiffness0.81.22.2-1.0-0.90.9-1.1-1.51.1-1.1-1.1-1.1-1.3-0.9
Tibialis anterior weight0.30.91.3-1.1-1.11.1-1.2-1.11.2-0.8-0.8-0.7-1.0-0.0
Time to tail flick, vehicle, before self-admin0.30.30.70.80.00.20.6-0.5-0.50.50.50.70.4-0.8
Time to tail flick, vehicle, after self-admin0.81.01.31.10.9-0.81.11.1-1.11.11.11.01.00.3
Time to tail flick, test, before self-admin0.20.21.10.00.3-0.30.3-0.1-0.20.40.40.30.51.0
Time to tail flick, test, after self-admin0.90.92.20.9-0.20.20.61.0-0.71.11.11.51.31.2
Delta time to tail flick, vehicle, before/after SA0.40.32.00.1-0.40.30.01.4-0.10.30.30.60.40.8
Delta time to tail flick, test, before/after SA0.40.41.70.1-1.31.3-0.5-0.10.5-0.4-0.40.4-0.2-0.7
Tibia length0.51.32.9-0.31.7-1.70.2-1.4-0.2-0.8-0.8-1.7-1.1-1.3
Ambulatory time before self-admin0.10.10.50.2-0.30.3-0.1-0.60.1-0.2-0.2-0.0-0.2-0.7
Ambulatory time after self-admin0.20.30.9-0.60.8-0.8-0.1-0.60.1-0.2-0.2-0.9-0.10.4
Bone: tissue strength0.60.60.9-0.6-0.80.7-0.8-0.60.8-0.8-0.8-0.7-1.0-0.8
Total heroin consumption0.20.20.40.40.6-0.60.50.3-0.50.60.60.20.30.2
Bone: trabecular number0.81.35.40.1-2.32.3-0.8-0.30.8-0.4-0.31.0-0.2-0.7
Bone: trabecular spacing0.70.93.9-0.42.0-1.90.5-0.1-0.4-0.2-0.2-1.3-0.30.3
Bone: trabecular thickness1.01.24.5-0.2-2.12.1-1.0-0.61.0-0.6-0.60.4-0.5-0.9
Bone: trabecular tissue density0.50.83.2-0.11.2-1.20.60.7-0.60.60.6-0.00.81.8
Water consumed over 24 hours0.30.40.70.70.8-0.80.80.6-0.80.70.70.40.5-0.1
Number of responses in last shaping day1.92.15.40.82.3-2.31.51.6-1.51.31.30.21.20.8