Hub : Genes

Lrrc29

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability Lrrc29 0.03 0.03 2.8e-03 0.02 0.02 0.01 0.02 2.6e-03 4.9e-03 3.8e-02 2.2e-03
2 Liver gene expression Lrrc29 0.05 0.05 3.9e-05 0.03 0.03 0.02 0.03 6.1e-04 1.0e-04 1.0e-03 1.3e-04
3 NAcc gene expression Lrrc29 0.06 0.05 8.0e-08 0.05 0.05 0.05 0.05 8.2e-08 9.1e-08 1.1e-07 1.6e-07
4 BLA gene expression Lrrc29 0.07 0.06 1.1e-03 0.06 0.05 0.05 0.06 2.4e-04 8.6e-04 1.0e-03 6.0e-04
5 Brain alternative polyA XM_039097947.2 0.05 0.04 8.7e-04 0.03 0.02 0.01 0.02 5.3e-04 3.9e-03 5.0e-02 2.8e-03
6 Brain alternative polyA NM_001401289.1 0.04 0.04 2.5e-03 0.02 0.01 0 0.01 7.7e-03 2.6e-02 1.2e-01 1.5e-02
7 PL gene expression Lrrc29 0.08 0.06 3.3e-07 0.06 0.05 0.06 0.06 3.6e-07 2.9e-06 9.9e-07 5.6e-07
8 Adipose alternative polyA XM_039097947.2 0.03 0.03 5.5e-03 0.02 0.01 0.02 0.02 1.8e-03 1.9e-02 2.3e-03 3.3e-03
9 Adipose isoform ratio XM_039097947.2 0.02 0.03 9.9e-03 0.02 0.01 0.02 0.02 2.9e-03 2.1e-02 3.6e-03 4.4e-03
10 Adipose gene expression Lrrc29 0.03 0.05 5.0e-03 0.01 0 0.02 0.01 7.1e-03 1.7e-01 6.1e-03 2.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.00.10.10.10.10.2-0.20.3-0.2-0.20.30.3-0.3
Area under the delay curve0.20.30.7-0.40.20.00.1-0.10.40.4-0.9-0.90.7
BMI with tail0.00.10.20.50.20.20.4-0.30.0-0.0-0.4-0.40.4
BMI without tail0.00.10.40.10.10.20.2-0.00.30.3-0.6-0.60.6
Body weight0.41.52.31.51.21.21.3-1.21.01.0-1.3-1.31.4
Weight adjusted by age0.10.10.5-0.10.20.1-0.70.40.10.2-0.2-0.20.2
Bone surface0.81.42.01.41.41.31.1-1.21.11.1-1.0-1.01.1
Bone volume0.50.81.61.21.21.20.7-0.80.80.8-0.7-0.70.8
Breakpoint value in progressive ratio session2.63.14.0-1.7-1.8-1.6-1.91.7-2.0-1.91.71.7-1.7
Number of licking bursts0.40.71.30.70.90.81.0-0.91.10.9-0.7-0.70.6
Context. condit. distance diff. score0.00.00.1-0.2-0.1-0.40.3-0.10.0-0.0-0.1-0.10.1
Locomotion velocity, session 10.20.20.30.40.30.20.4-0.40.50.4-0.6-0.60.6
Locomotion distance, session 10.00.00.1-0.2-0.2-0.20.0-0.0-0.1-0.10.20.2-0.2
Locomotion velocity, session 20.40.40.8-0.9-0.7-0.6-0.50.6-0.6-0.60.60.6-0.7
Locomotion distance, session 20.00.00.0-0.1-0.2-0.20.1-0.10.00.0-0.0-0.00.0
Locomotion velocity, session 30.30.30.5-0.7-0.6-0.6-0.40.6-0.4-0.50.60.6-0.6
Locomotion distance, session 30.10.10.2-0.00.1-0.20.5-0.30.40.4-0.2-0.20.3
Stereotopy head waving bouts, day 30.10.10.20.20.30.50.4-0.40.40.4-0.2-0.20.2
Stereotopy head waving duration, day 30.20.30.80.60.60.90.5-0.50.40.5-0.4-0.40.4
Locomotion velocity, session 70.20.20.4-0.4-0.3-0.3-0.50.5-0.7-0.50.50.5-0.5
Locomotion distance, session 70.00.00.2-0.3-0.2-0.4-0.20.3-0.3-0.20.00.00.0
Stereotopy head waving bouts, day 70.00.00.10.10.20.20.10.00.10.10.40.4-0.3
Stereotopy head waving duration, day 70.10.20.30.50.60.60.4-0.40.50.5-0.0-0.00.0
Locomotion velocity, session 80.40.50.8-0.5-0.5-0.2-0.90.8-0.7-0.80.80.8-0.8
Locomotion distance, session 80.10.20.8-0.6-0.6-0.9-0.00.2-0.3-0.40.20.2-0.2
Degree of sensitization distance0.00.00.00.10.0-0.0-0.10.1-0.2-0.1-0.2-0.20.2
Degree of sensitization stereotypy0.10.10.20.40.40.40.3-0.20.30.30.00.0-0.0
Conditioned locomotion2.12.42.81.61.61.71.6-1.71.51.6-1.4-1.41.4
Cocaine response after cond. corrected0.10.10.30.60.50.40.1-0.30.40.4-0.0-0.00.1
Cocaine response after cond. not corrected0.00.00.10.1-0.0-0.1-0.00.10.10.10.30.3-0.3
Cocaine response before conditioning0.50.71.8-1.1-1.0-1.3-0.20.6-0.6-0.60.70.7-0.7
Saline control response4.56.07.62.42.52.82.4-2.42.52.4-2.4-2.42.4
Bone: connectivity density0.20.30.5-0.4-0.4-0.3-0.50.6-0.6-0.60.70.7-0.7
Bone: cortical apparent density1.41.92.4-1.4-1.3-1.3-1.51.4-1.2-1.31.41.4-1.4
Bone: cortical area0.10.20.40.50.60.70.5-0.40.40.4-0.2-0.20.2
Bone: cortical porosity0.10.10.1-0.3-0.3-0.3-0.1-0.1-0.1-0.10.30.3-0.3
Bone: cortical porosity0.10.10.1-0.3-0.3-0.3-0.1-0.1-0.1-0.00.30.3-0.3
Bone: cortical thickness0.10.10.3-0.00.10.4-0.40.5-0.4-0.50.40.4-0.4
Bone: cortical thickness0.00.00.10.20.10.30.20.10.1-0.0-0.3-0.30.3
Bone: cortical tissue density1.41.92.4-1.4-1.3-1.3-1.61.4-1.2-1.31.41.4-1.4
Condit. Reinf. active minus inactive responses3.23.64.9-2.0-2.1-2.2-1.81.8-1.9-1.81.71.7-1.7
Condit. Reinf. active-inactive response ratio2.52.74.8-1.9-1.8-2.2-1.41.4-1.6-1.51.51.5-1.5
Condit. Reinf. active responses1.92.33.5-1.7-1.7-1.9-1.41.4-1.5-1.51.31.3-1.3
Condit. Reinf. inactive responses0.10.10.1-0.3-0.4-0.4-0.30.3-0.2-0.30.20.2-0.2
Incentive salience index mean1.82.22.6-1.6-1.6-1.6-1.41.4-1.5-1.51.41.4-1.4
Condit. Reinf. lever presses0.30.40.5-0.6-0.5-0.3-0.60.7-0.7-0.70.70.7-0.7
Condit. Reinf. active minus inactive responses1.01.31.81.11.10.91.3-1.11.21.2-1.2-1.21.2
Condit. Reinf. active-inactive response ratio0.40.40.60.80.80.70.8-0.50.50.5-0.7-0.70.6
Condit. Reinf. active responses0.70.91.40.90.90.71.2-0.91.01.0-1.0-1.01.0
Condit. Reinf. inactive responses0.00.00.1-0.3-0.2-0.20.10.00.10.10.00.0-0.0
Condit. Reinf. lever presses2.23.03.4-1.8-1.8-1.8-1.71.9-1.7-1.71.61.6-1.6
Condit. Reinf. lever reinforcers received0.10.20.40.40.30.20.6-0.30.40.4-0.4-0.40.4
Conditioned reinforcement - actives0.20.30.7-0.5-0.7-0.80.7-0.8-0.30.00.30.3-0.3
Conditioned reinforcement - inactives0.10.20.50.70.2-0.40.5-0.60.10.2-0.4-0.40.4
Conditioned locomotion0.81.01.81.20.80.41.3-1.31.01.0-0.9-0.90.9
Patch foraging indifference point 0 sec3.66.68.02.52.52.42.4-2.52.52.4-2.8-2.82.8
Patch foraging indifference point AUC1.52.13.21.51.61.61.8-1.41.61.6-1.0-1.01.0
Delay disc. indifference point, 0s delay0.70.81.5-1.2-0.8-0.8-1.01.1-0.9-0.90.60.6-0.6
Delay disc. indifference point, 16s delay1.21.32.20.50.80.71.0-1.21.11.1-1.5-1.51.4
Delay disc. indifference point, 2s delay0.10.10.3-0.10.4-0.10.10.00.30.4-0.6-0.60.5
Delay disc. indifference point, 24s delay0.40.41.00.30.30.10.7-1.00.40.5-0.9-0.90.8
Delay disc. indifference point, 4s delay0.60.61.7-1.3-0.6-0.7-0.90.8-0.7-0.70.60.6-0.7
Delay disc. indifference point, 8s delay0.20.30.7-0.50.30.0-0.00.00.40.3-0.9-0.90.8
Indifference point function ln k0.10.10.7-0.3-0.5-0.8-0.30.1-0.1-0.1-0.1-0.10.1
Indifference point function log k0.10.10.7-0.3-0.5-0.8-0.30.1-0.1-0.1-0.1-0.10.1
Patch foraging total patch changes 0 sec3.56.68.02.52.52.42.4-2.52.52.4-2.8-2.82.8
Patch foraging total patch changes 12 sec3.24.14.82.02.12.02.2-2.02.12.0-2.0-2.01.9
Patch foraging total patch changes 18 sec3.14.85.42.32.22.12.3-2.22.22.1-2.1-2.12.2
Patch foraging total patch changes 24 sec0.00.10.20.30.50.30.10.00.30.2-0.2-0.20.2
Patch foraging total patch changes 6 sec1.42.22.81.41.71.71.4-1.11.61.5-1.5-1.51.4
Patch foraging time to switch 0 sec1.02.02.6-1.6-1.4-1.2-1.61.5-1.5-1.51.31.3-1.3
Patch foraging water rate 0 sec1.63.34.72.21.81.92.0-1.71.71.8-1.7-1.71.6
Patch foraging water rate 12 sec0.10.30.50.70.50.20.5-0.50.70.7-0.4-0.40.4
Patch foraging water rate 18 sec0.20.40.80.40.4-0.20.8-0.60.70.9-0.6-0.60.6
Patch foraging water rate 24 sec0.10.20.40.30.30.40.4-0.00.50.6-0.4-0.40.4
Patch foraging water rate 6 sec0.50.71.41.20.90.71.0-0.90.90.9-0.6-0.60.6
Seeking ratio, delayed vs. immediate footshock2.93.64.51.91.91.61.7-1.61.91.9-2.1-2.12.1
Distance traveled before self-admin0.00.00.1-0.20.3-0.2-0.30.0-0.00.00.20.2-0.2
Distance traveled after self-admin0.00.10.1-0.10.20.1-0.20.10.10.1-0.4-0.40.4
Extensor digitorum longus weight0.62.22.7-1.4-1.6-1.5-1.31.5-1.6-1.51.41.4-1.5
Bone: elastic displacement1.61.82.41.51.41.31.1-1.41.31.3-1.4-1.41.4
Bone: elastic work0.30.40.70.80.70.80.3-0.60.50.5-0.5-0.50.5
Bone: endosteal estimation0.30.81.00.80.60.40.9-1.00.90.9-1.0-1.01.0
Bone: endosteal perimeter0.61.22.01.00.90.51.4-1.41.21.3-1.0-1.01.1
Epididymis fat weight2.79.111.63.12.92.43.4-3.33.13.0-2.9-2.92.9
Delta time in closed arm before/after self-admin0.30.30.50.10.50.70.6-0.20.60.5-0.5-0.50.5
Delta time in open arm before/after self-admin0.80.82.2-0.4-0.5-1.0-1.41.5-0.6-0.70.70.7-0.7
Diff in mean of infusions in LGA sessions1.21.52.1-1.2-1.0-0.8-1.31.1-1.4-1.21.31.3-1.3
Delay discount exponential model param0.20.20.60.5-0.10.1-0.00.1-0.3-0.30.80.8-0.7
Extinction: sum of active levers before priming0.50.50.9-0.4-0.9-0.9-0.70.4-0.9-0.60.70.7-0.7
Active lever presses in extinction session 60.10.10.2-0.00.20.4-0.0-0.10.30.1-0.4-0.40.4
Bone: final force0.91.41.8-1.3-1.2-1.0-1.01.2-1.2-1.31.21.2-1.2
Bone: final moment0.40.60.7-0.9-0.8-0.6-0.60.8-0.8-0.80.80.8-0.8
Food consumed during 24 hour testing period2.02.83.91.31.20.71.8-2.01.81.8-1.9-1.91.9
Glucose1.52.33.0-1.6-1.6-1.7-1.31.3-1.5-1.51.51.5-1.4
Heart weight0.00.00.10.1-0.2-0.3-0.10.1-0.2-0.10.00.0-0.0
Delay discount hyperbolic model param0.10.20.50.70.00.20.2-0.1-0.1-0.10.60.6-0.5
Intermittent access intake day 1-15 change0.30.61.5-1.1-1.2-1.2-0.60.3-0.9-0.70.40.4-0.4
Intermittent access intake escalation0.40.81.9-1.2-1.3-1.4-0.80.5-1.0-0.80.50.5-0.5
Intermittent access intake escalation 20.10.20.5-0.6-0.7-0.7-0.2-0.0-0.5-0.3-0.1-0.10.0
Intermitt. access day 1 inactive lever presses0.00.10.30.10.1-0.10.1-0.10.40.4-0.5-0.50.6
Intermitt. access day 15 inactive lever presses0.10.20.9-0.2-0.5-0.9-0.20.3-0.5-0.60.30.3-0.4
Intermitt. access escalation Index0.10.20.40.20.60.60.2-0.30.50.4-0.3-0.30.3
Intermittent access day 1 total infusions0.20.30.90.10.20.20.9-1.00.50.6-0.4-0.40.4
Intermittent access day 15 total infusions0.30.41.4-1.0-1.1-1.20.1-0.4-0.5-0.30.30.3-0.3
Intermittent access terminal intake (last 3 days)0.60.82.3-1.2-1.4-1.5-0.1-0.2-0.9-0.60.50.5-0.6
Intermittent access total infusions0.40.51.3-1.0-1.1-1.10.1-0.3-0.5-0.40.50.5-0.6
Intermittent access day 1 locomotion1.92.43.01.31.51.31.6-1.61.71.6-1.6-1.61.5
Intermittent access day 15 total locomotion0.50.81.30.80.70.50.8-0.80.90.9-1.1-1.11.1
Intermittent access total locomotion0.20.20.40.40.30.10.6-0.60.40.3-0.6-0.60.6
Intermittent access standard deviation0.20.40.50.70.50.40.5-0.70.50.6-0.7-0.70.7
Left kidney weight1.36.09.7-2.4-2.7-3.1-2.02.3-2.6-2.52.22.2-2.2
Right kidney weight1.46.69.2-2.5-2.7-3.0-2.52.6-2.8-2.62.22.2-2.2
Cocaine induced anxiety1.41.93.61.91.61.71.3-1.11.01.0-1.3-1.31.3
Post-drug Anxiety0.50.50.80.90.60.60.7-0.70.40.4-0.8-0.80.8
Baseline Anxiety0.30.41.5-1.1-0.9-1.2-0.40.2-0.2-0.20.10.1-0.3
Tail length0.10.30.60.30.50.50.3-0.30.70.8-0.7-0.70.8
Length with tail0.20.81.01.00.90.80.6-0.70.90.8-1.0-1.01.0
Length without tail0.51.72.61.61.31.11.3-1.41.21.1-1.3-1.31.3
Times rat made contact with spout2.02.32.81.31.51.51.3-1.71.71.5-1.6-1.61.6
Lifetime Intake0.30.41.0-1.0-1.0-1.00.0-0.3-0.5-0.30.50.5-0.5
Liver weight, left0.10.20.40.50.40.60.3-0.2-0.00.1-0.6-0.60.6
Liver weight, right0.50.91.11.10.91.00.8-1.00.90.9-0.9-0.91.1
Locomotor activity1.42.24.11.81.82.01.4-1.11.41.3-1.3-1.31.3
Locomotor testing distance1.42.54.61.81.82.11.5-1.21.51.4-1.5-1.51.5
Locomotor testing rearing0.00.10.40.60.30.70.20.00.0-0.00.10.1-0.0
Locomotion in novel chamber2.02.53.11.71.81.61.3-1.41.61.7-1.6-1.61.6
Locomotion in novel chamber post-restriction1.52.44.21.41.82.01.3-0.91.81.5-1.5-1.51.6
Fecal boli incidents, locomotor time 10.91.34.11.01.32.01.0-1.01.21.1-0.7-0.70.7
Change in fecal boli incidents, locomotor task0.30.31.1-0.6-0.7-1.1-0.20.3-0.5-0.50.30.3-0.3
Time >=10cm from walls, locomotor time 10.70.71.40.31.01.20.5-0.51.11.0-0.8-0.80.9
Bouts of movement, locomotor time 10.10.10.40.50.20.50.2-0.6-0.1-0.10.10.10.1
Total resting periods, locomotor time 10.10.10.20.1-0.10.30.1-0.4-0.3-0.30.40.4-0.3
Rest time, locomotor task time 10.70.81.8-0.5-0.5-0.1-0.70.6-0.9-1.01.21.2-1.3
Distance moved, locomotor task time 10.50.71.30.60.50.20.6-0.70.81.0-1.1-1.11.2
Vertical activity count, locomotor time 11.22.83.81.41.41.21.7-1.71.71.8-1.9-1.91.9
Time >=10cm from walls, locomotor time 20.61.01.6-1.1-0.8-0.4-1.01.3-0.8-0.81.11.1-1.1
Bouts of movement, locomotor time 20.50.81.2-0.9-1.0-0.9-0.40.4-1.0-1.11.01.0-1.0
Total resting periods, locomotor time 20.71.21.8-1.0-1.2-1.0-0.60.6-1.2-1.31.21.2-1.2
Rest time, locomotor task time 20.30.40.6-0.6-0.7-0.4-0.50.3-0.7-0.80.70.7-0.8
Distance moved, locomotor task time 20.30.30.50.70.60.30.4-0.40.40.6-0.7-0.70.7
Vertical activity count, locomotor time 21.11.51.81.31.10.91.2-1.21.11.2-1.3-1.31.3
Light reinforcement 12.04.95.92.42.32.12.1-2.12.22.2-2.2-2.22.3
Light reinforcement 22.53.85.11.72.01.91.7-1.51.92.0-2.3-2.32.2
Bone: marrow area0.30.71.00.70.60.40.9-1.00.80.9-0.9-0.90.9
Bone: maximum diameter0.61.21.81.11.10.81.4-1.21.21.2-0.9-0.90.9
Bone: maximum force0.50.91.3-0.9-0.8-0.7-0.90.9-0.9-1.01.11.1-1.1
Bone: maximum moment0.10.30.5-0.5-0.4-0.3-0.40.5-0.4-0.50.70.7-0.7
Mean time between licks in bursts0.10.20.40.30.3-0.30.4-0.40.60.5-0.6-0.60.6
Mean num. licks in bursts0.10.10.30.30.20.3-0.0-0.30.10.2-0.5-0.50.5
Cd content in liver0.20.20.4-0.3-0.4-0.5-0.60.5-0.5-0.50.50.5-0.6
Co content in liver0.00.10.2-0.2-0.2-0.1-0.1-0.0-0.0-0.10.30.3-0.4
Cu content in liver0.50.61.0-1.0-0.9-0.8-0.50.6-0.7-0.60.80.8-0.9
Fe content in liver1.11.43.41.21.41.91.1-0.91.01.0-1.0-1.00.9
K content in liver0.00.00.1-0.1-0.1-0.30.3-0.20.20.2-0.2-0.20.2
Mg content in liver0.90.91.20.80.80.70.9-1.01.11.0-1.0-1.01.0
Mn content in liver0.91.01.51.10.90.70.7-1.01.10.8-1.2-1.21.2
Na content in liver0.00.00.1-0.20.00.00.00.10.10.20.00.0-0.0
Rb content in liver0.10.10.2-0.3-0.4-0.4-0.40.1-0.3-0.20.40.4-0.3
Se content in liver0.10.10.2-0.2-0.2-0.2-0.10.1-0.2-0.30.30.3-0.4
Sr content in liver1.51.31.51.21.10.90.9-1.21.21.2-1.2-1.21.2
Zn content in liver0.80.91.8-1.2-1.2-1.3-0.80.6-0.7-0.70.80.8-0.9
Bone: minimum diameter0.10.20.50.50.50.50.7-0.50.30.4-0.2-0.20.2
Time in familiar zone, hab. session 10.30.30.70.80.50.30.5-0.50.60.6-0.5-0.50.5
Time in novel zone, hab. session 10.50.50.8-0.9-0.6-0.2-0.80.7-0.8-0.90.70.7-0.8
Total zone transitions, hab. session 11.11.52.01.31.21.11.4-1.11.11.2-1.3-1.31.3
Total locomotion distance, hab. session 11.21.72.21.41.31.31.3-1.11.11.1-1.5-1.51.5
Locomotion velocity, hab. session 11.72.32.91.61.51.51.6-1.41.41.4-1.7-1.71.7
Time in familiar zone, hab. session 20.50.50.70.80.80.70.7-0.70.70.7-0.7-0.70.7
Time in novel zone, hab. session 25.05.05.3-2.3-2.3-2.0-2.32.3-2.3-2.32.32.3-2.3
Total zone transitions, hab. session 21.72.23.51.61.61.91.3-1.31.31.3-1.5-1.51.5
Total locomotion distance, hab. session 21.31.82.01.41.41.41.2-1.21.21.2-1.4-1.41.4
Locomotion velocity, hab. session 21.21.61.91.41.31.41.2-1.11.11.1-1.4-1.41.4
Novel to familiar place preference ratio2.52.83.3-1.7-1.7-1.8-1.61.7-1.7-1.61.61.6-1.6
Novelty place preference4.14.44.8-2.2-2.1-2.2-2.02.1-2.1-2.12.12.1-2.1
Time in novel zone, NPP test3.84.14.5-2.1-2.0-2.1-1.92.0-2.0-2.02.02.0-2.0
Total zone transitions, NPP test1.82.53.11.71.61.71.7-1.61.51.5-1.5-1.51.5
Total locomotion distance, NPP test0.81.11.81.21.11.31.0-1.00.90.9-1.0-1.01.1
Locomotion velocity, NPP test0.71.01.61.11.11.30.9-0.90.80.8-1.0-1.01.0
Intraocular pressure0.71.11.4-0.7-1.0-0.9-0.71.1-1.1-1.21.21.2-1.1
Delta distance traveled before/after self-admin0.20.20.4-0.1-0.6-0.6-0.30.6-0.4-0.60.10.1-0.1
Delta ambulatory time before/after self-admin0.20.20.4-0.5-0.7-0.6-0.30.6-0.4-0.50.10.1-0.1
Parametrial fat weight6.014.118.54.33.93.93.9-3.93.63.6-3.5-3.53.5
Pavlov. Cond. lever latency0.30.30.50.50.40.00.5-0.50.60.7-0.7-0.70.7
Pavlov. Cond. magazine entry latency0.30.30.5-0.7-0.7-0.5-0.50.5-0.6-0.60.60.6-0.5
Pavlov. Cond. change in total contacts1.01.11.2-1.1-1.0-0.9-1.01.0-1.0-1.11.11.1-1.1
Pavlov. Cond. index score0.30.40.6-0.8-0.6-0.4-0.50.6-0.7-0.80.70.7-0.7
Pavlov. Cond. latency score0.30.40.5-0.7-0.6-0.3-0.50.5-0.6-0.70.70.7-0.7
Pavlov. Cond. lever contacts0.91.01.4-1.0-0.9-0.6-1.00.9-1.1-1.11.21.2-1.1
Pavlov. Cond. magazine entry number0.20.20.50.70.70.60.4-0.30.50.5-0.4-0.40.4
Pavlov. Cond. intertrial magazine entries0.40.50.70.60.60.40.8-0.60.80.8-0.7-0.70.8
Pavlov. Cond. lever-magazine prob. diff.0.40.50.7-0.8-0.7-0.4-0.60.6-0.7-0.80.80.8-0.7
Pavlov. Cond. response bias0.20.20.4-0.6-0.5-0.3-0.40.4-0.6-0.60.50.5-0.4
Pavlov. Cond. lever latency1.01.41.81.31.31.21.3-1.31.11.2-1.1-1.11.0
Pavlov. Cond. magazine entry latency3.13.74.3-2.1-2.0-2.1-2.02.0-1.9-2.01.71.7-1.7
Pavlov. Cond. change in total contacts1.82.83.0-1.7-1.7-1.7-1.61.7-1.6-1.71.71.7-1.7
Pavlov. Cond. index score2.93.94.6-2.1-2.1-2.1-2.12.1-2.0-2.01.81.8-1.8
Pavlov. Cond. latency score2.93.94.5-2.1-2.1-2.1-2.02.0-2.0-2.01.81.8-1.8
Pavlov. Cond. lever contacts1.21.62.0-1.4-1.4-1.3-1.41.3-1.2-1.31.11.1-1.1
Pavlov. Cond. magazine entry number5.26.47.12.72.62.62.6-2.62.62.6-2.3-2.32.3
Pavlov. Cond. intertrial magazine entries4.16.18.12.72.62.92.7-2.42.52.5-2.2-2.22.2
Pavlov. Cond. lever-magazine prob. diff.3.14.25.0-2.2-2.2-2.2-2.12.1-2.0-2.01.91.9-1.9
Pavlov. Cond. response bias2.63.64.3-2.1-2.0-1.9-2.02.0-1.9-1.91.71.7-1.7
Time in closed arm before self-admin3.34.37.12.61.91.82.5-2.71.81.8-1.7-1.71.7
Time in closed arm after self-admin2.02.13.21.41.71.81.8-1.71.31.2-1.2-1.21.2
Time in open arm before self-admin1.11.22.7-1.7-1.1-1.2-1.11.2-1.0-0.80.80.8-0.8
Time in open arm after self-admin1.11.23.0-1.0-0.9-1.2-1.61.7-0.8-0.80.80.8-0.8
Bone: periosteal estimation0.30.60.80.90.80.70.9-0.90.80.8-0.8-0.80.8
Bone: periosteal perimeter0.71.21.91.21.21.01.4-1.21.21.2-0.8-0.80.8
Bone: post-yield work0.30.50.80.60.80.60.8-0.70.90.8-0.5-0.50.5
Progressive ratio test 1 active lever presses0.81.02.3-1.5-1.4-1.5-0.40.4-0.7-0.50.80.8-0.9
Progressive ratio test 1 breakpoint0.70.82.0-1.4-1.3-1.4-0.30.3-0.6-0.40.80.8-0.8
Progressive ratio test 1 inactive lever presses0.10.10.2-0.10.0-0.10.3-0.30.40.3-0.5-0.50.4
Progressive ratio test 2 active lever presses0.20.31.0-1.0-0.9-0.80.2-0.3-0.2-0.1-0.1-0.10.0
Progressive ratio test 2 breakpoint0.30.31.1-1.1-0.9-0.80.1-0.2-0.3-0.2-0.0-0.0-0.0
Progressive ratio test 2 inactive lever presses0.00.10.2-0.1-0.3-0.40.4-0.4-0.1-0.0-0.2-0.20.2
Incentive Sensitization - Responses0.10.10.2-0.4-0.4-0.10.5-0.5-0.00.0-0.5-0.50.4
Incentive Sensitization - Breakpoint0.10.10.2-0.5-0.5-0.20.4-0.4-0.1-0.1-0.4-0.40.3
Sum of active levers in priming session hrs 5-60.60.50.7-0.7-0.7-0.8-0.50.9-0.7-0.70.80.8-0.8
Progressive ratio0.81.22.5-0.8-0.5-0.7-1.61.4-1.3-1.21.01.0-1.0
Food seeking constrained by brief footshock2.42.94.6-1.7-1.5-1.4-2.22.0-1.6-1.41.71.7-1.7
Seeking ratio, punishment vs. effort0.10.10.3-0.5-0.5-0.6-0.10.20.10.00.20.2-0.3
Retroperitoneal fat weight5.925.329.85.55.34.95.0-4.95.04.9-4.9-4.94.9
Reaction time number correct0.50.91.4-1.1-1.2-1.2-0.50.6-0.9-0.90.90.9-0.9
Reaction time mean minus median1.33.24.4-1.5-1.6-1.3-2.11.9-2.1-2.01.81.8-1.7
Reaction time mean minus median AUC1.12.84.1-1.3-1.4-1.2-2.01.7-2.0-2.01.71.7-1.6
Reaction time num false alarms0.00.10.3-0.2-0.2-0.50.40.2-0.10.0-0.0-0.00.0
Reaction time num false alarms AUC0.10.20.90.30.30.11.0-0.30.50.5-0.5-0.50.5
Reaction time trials correct on left0.50.91.4-1.1-1.2-1.2-0.50.6-0.9-0.90.90.9-0.9
Reaction time trials on left0.50.91.5-1.2-1.2-1.2-0.50.6-0.9-0.90.90.9-0.9
Reaction time mean1.11.73.1-0.7-0.9-0.9-1.81.6-1.6-1.51.31.3-1.3
Reaction time mean AUC1.52.44.0-0.9-1.1-1.2-2.01.8-1.8-1.71.51.5-1.5
Median of all reaction times0.50.81.6-0.3-0.4-0.7-1.31.1-1.0-0.90.90.9-0.8
Reaction time omissions0.40.71.20.40.60.70.6-0.70.70.8-1.1-1.11.1
Reaction time false alarm rate0.50.71.30.80.80.61.2-0.50.80.9-0.9-0.90.9
Reaction time premature initiation rate1.72.32.9-1.3-1.5-1.3-1.61.5-1.6-1.71.61.6-1.5
Reaction time premature initiations2.34.14.8-2.0-2.1-1.9-1.91.9-2.1-2.22.12.1-2.0
Std. dev. reaction times1.32.33.6-1.1-1.1-0.9-1.91.8-1.8-1.71.61.6-1.5
Reaction time trials completed0.50.91.5-1.2-1.2-1.2-0.50.6-0.9-0.90.90.9-0.9
Reaction time trials AUC0.51.01.6-1.2-1.3-1.2-0.60.7-1.0-1.01.01.0-1.1
Run reversals in cocaine runway, females2.22.13.31.81.51.61.2-1.21.71.5-1.3-1.31.3
Run reversals in cocaine runway, males1.31.32.01.10.91.11.4-0.91.31.0-1.2-1.21.1
Latency to leave start box in cocaine runway0.40.50.80.1-0.7-0.7-0.70.5-0.9-0.80.80.8-0.8
Latency to leave start box in cocaine runway, F1.01.11.4-0.8-1.2-1.0-1.01.0-1.1-1.01.11.1-1.2
Latency to leave start box in cocaine runway, M0.30.31.91.40.50.30.0-0.4-0.2-0.1-0.2-0.20.2
Std. dev. time between licks in bursts2.02.83.11.71.71.51.6-1.61.71.7-1.7-1.71.8
Total sessions with >9 infusions0.20.20.8-0.9-0.8-0.8-0.10.0-0.2-0.20.20.2-0.3
Short access day 1 total inactive lever presses0.00.00.1-0.2-0.00.2-0.30.2-0.2-0.20.20.2-0.1
Short access day 10 total inactive lever presses0.10.30.50.50.60.6-0.20.10.50.4-0.6-0.60.7
Short access day 1 total infusions0.10.20.5-0.3-0.00.10.5-0.70.40.4-0.4-0.40.4
Short access day 10 total infusions0.10.20.8-0.1-0.1-0.20.7-0.90.30.4-0.3-0.30.3
Short access total infusions0.30.41.2-1.1-0.9-0.9-0.1-0.1-0.4-0.30.50.5-0.5
Short access day 1 locomotion0.10.10.2-0.2-0.10.10.1-0.30.10.1-0.5-0.50.4
Short access day 10 total locomotion1.32.53.21.71.61.41.3-1.31.61.5-1.8-1.81.7
Short access total locomotion0.50.60.80.80.60.50.8-0.80.70.6-0.9-0.90.8
One hour access (0.3 mA shock)0.10.20.4-0.6-0.6-0.40.4-0.5-0.3-0.10.10.1-0.1
Compulsive drug intake0.00.00.10.00.30.4-0.30.2-0.1-0.2-0.1-0.10.1
One hour access (shock baseline)0.10.20.5-0.5-0.7-0.60.5-0.7-0.10.00.10.1-0.1
Social response proportion0.10.10.5-0.5-0.3-0.70.3-0.40.20.2-0.1-0.10.1
Social responses0.20.20.5-0.00.30.00.7-0.70.70.7-0.3-0.30.3
Social time0.20.30.70.30.3-0.10.6-0.80.70.8-0.5-0.50.6
Soleus weight0.10.30.50.60.70.70.4-0.50.50.5-0.5-0.50.5
Bone: stiffness3.04.95.8-2.4-2.3-2.3-2.02.2-2.1-2.22.22.2-2.2
Tibialis anterior weight0.10.40.6-0.7-0.7-0.5-0.70.7-0.8-0.70.60.6-0.6
Time to tail flick, vehicle, before self-admin0.20.20.6-0.8-0.4-0.3-0.70.4-0.4-0.20.50.5-0.5
Time to tail flick, vehicle, after self-admin2.33.16.71.41.41.61.9-2.61.71.9-1.6-1.61.6
Time to tail flick, test, before self-admin4.95.17.92.12.02.22.6-2.82.22.1-2.1-2.12.1
Time to tail flick, test, after self-admin1.11.22.80.90.70.51.5-1.71.11.1-1.0-1.01.0
Delta time to tail flick, vehicle, before/after SA2.32.24.31.61.11.31.9-2.11.31.3-1.3-1.31.3
Delta time to tail flick, test, before/after SA0.60.71.3-1.0-0.9-1.1-0.90.9-0.7-0.60.60.6-0.6
Tibia length0.10.30.4-0.2-0.4-0.1-0.60.6-0.6-0.60.60.6-0.6
Ambulatory time before self-admin0.20.30.70.50.80.40.5-0.70.60.7-0.5-0.50.5
Ambulatory time after self-admin0.20.30.6-0.10.50.30.2-0.20.50.5-0.7-0.70.7
Bone: tissue strength0.20.20.3-0.5-0.5-0.6-0.30.3-0.3-0.30.40.4-0.4
Total heroin consumption0.91.01.4-1.1-1.2-1.0-1.20.9-1.1-0.90.90.9-0.9
Bone: trabecular number0.00.10.30.50.40.50.2-0.00.10.10.10.1-0.0
Bone: trabecular spacing0.50.71.20.70.60.40.7-0.80.70.8-1.1-1.11.1
Bone: trabecular thickness1.72.13.4-1.3-1.1-0.8-1.41.4-1.4-1.41.81.8-1.8
Bone: trabecular tissue density0.91.41.6-1.2-1.1-1.0-1.21.2-1.2-1.21.21.2-1.2
Water consumed over 24 hours0.70.91.20.80.90.70.9-1.11.11.0-1.1-1.11.0
Number of responses in last shaping day1.01.12.4-0.9-1.1-1.5-0.91.0-1.0-1.11.01.0-1.1