Hub : Genes

Lin54

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc mRNA stability Lin54 0.03 0.02 9.4e-04 0.01 0.01 0.01 0.01 1.9e-02 5.7e-03 1.6e-02 5.8e-02
2 pVTA alternative TSS XM_006250659.4 0.07 0.04 7.4e-03 0.01 0.02 -0 0.02 7.5e-02 3.1e-02 5.4e-01 5.9e-02
3 Brain alternative TSS XM_006250659.4 0.08 0.04 3.5e-08 0.06 0.07 0.07 0.06 3.4e-06 5.5e-07 6.6e-07 1.9e-06
4 Brain alternative TSS XM_006250659.4 0.09 0.04 3.1e-08 0.06 0.07 0.08 0.08 2.0e-06 8.7e-07 1.2e-07 1.4e-07
5 PL gene expression Lin54 0.19 0.07 2.8e-09 0.09 0.08 0.08 0.08 6.5e-10 3.2e-09 3.0e-09 1.6e-09
6 Brain isoform ratio XM_006250659.4 0.06 0.03 1.3e-05 0.05 0.04 0.05 0.05 3.3e-05 9.5e-05 1.2e-05 1.4e-05
7 PL alternative TSS XM_039091835.1 0.06 0.04 9.9e-03 0.02 0 0.01 0.02 2.5e-03 1.4e-01 2.2e-02 5.3e-03
8 Adipose gene expression Lin54 0.42 0.11 0.0e+00 0.15 0.21 0.2 0.21 6.4e-16 7.1e-23 2.2e-22 2.1e-22
9 Adipose mRNA stability Lin54 0.04 0.02 7.6e-03 0.02 0 0 0.01 1.7e-03 1.1e-01 3.1e-01 8.8e-03
10 PL mRNA stability Lin54 0.06 0.03 4.2e-06 0.05 0.05 0.06 0.05 4.8e-06 1.6e-06 1.1e-06 2.1e-06
11 Brain gene expression Lin54 0.22 0.08 7.1e-09 0.12 0.1 0.1 0.11 8.0e-11 2.4e-09 6.4e-10 2.2e-10
12 NAcc gene expression Lin54 0.15 0.06 6.7e-07 0.07 0.05 0.05 0.06 4.2e-08 7.7e-07 4.0e-06 2.4e-07
13 pVTA gene expression Lin54 0.28 0.12 6.1e-05 0.11 0.07 0.09 0.1 1.7e-05 5.2e-04 1.0e-04 3.3e-05
14 Brain mRNA stability Lin54 0.03 0.02 7.2e-03 0.02 0.01 0.02 0.01 3.6e-03 3.6e-02 8.8e-03 1.3e-02
15 BLA gene expression Lin54 0.31 0.1 1.2e-09 0.14 0.19 0.15 0.19 3.8e-08 1.3e-10 1.7e-08 2.1e-10
16 NAcc intron excision ratio chr14_9132103_9146114 0.03 0.02 3.4e-03 0.01 0.01 0.01 0.02 1.3e-02 4.3e-02 3.1e-02 4.9e-03
17 Liver gene expression Lin54 0.28 0.08 0.0e+00 0.19 0.25 0.25 0.24 2.3e-20 4.5e-27 3.4e-27 5.8e-26
18 NAcc alternative TSS NM_001100564.1 0.02 0.01 7.6e-03 0.01 0.01 0 0 3.7e-02 6.4e-02 2.0e-01 6.8e-02
19 Brain intron excision ratio chr14_9132103_9146114 0.03 0.02 3.5e-03 0.02 0.01 0.01 0.01 5.2e-03 2.7e-02 2.0e-02 5.8e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density3.96.610.0-2.83.12.5-2.5-3.0-2.43.22.6-1.72.2-3.0-3.0-3.02.52.32.7-2.31.3-1.1
Area under the delay curve0.50.62.9-0.2-0.10.6-0.40.9-0.5-0.9-0.3-1.00.90.80.80.8-0.20.30.2-0.11.1-1.7
BMI with tail1.65.112.5-1.21.31.8-2.6-2.4-2.72.41.8-2.31.1-2.3-2.3-2.30.32.32.2-2.93.5-3.1
BMI without tail1.42.86.5-0.81.00.9-1.7-2.5-1.62.21.1-0.90.4-2.1-2.1-2.11.11.12.5-1.81.8-1.7
Body weight2.510.515.3-3.02.73.1-3.8-3.8-3.73.93.4-3.32.4-3.8-3.8-3.82.23.32.5-3.22.9-2.2
Weight adjusted by age1.21.33.3-1.71.21.6-1.3-0.8-1.40.81.5-1.81.3-0.7-0.7-0.71.41.30.6-0.30.5-0.5
Bone surface2.24.07.7-2.42.82.2-2.2-2.1-2.02.12.1-1.62.1-2.0-2.0-2.01.81.91.8-1.71.4-1.1
Bone volume3.15.28.6-2.62.92.3-2.3-2.8-2.12.72.8-1.52.3-2.7-2.7-2.72.12.31.8-1.80.9-0.6
Breakpoint value in progressive ratio session0.00.10.10.2-0.2-0.00.1-0.30.10.30.00.1-0.1-0.3-0.3-0.3-0.20.2-0.10.40.30.3
Number of licking bursts0.50.61.10.9-0.8-0.80.70.90.8-0.7-0.70.8-0.70.70.70.7-0.8-0.8-0.60.7-0.31.1
Context. condit. distance diff. score1.31.54.4-0.91.11.2-1.2-0.8-1.21.22.1-1.31.2-1.2-1.2-1.2-1.12.0-1.2-1.20.4-0.6
Locomotion velocity, session 10.40.41.4-1.11.20.9-0.50.3-0.5-0.20.5-0.71.00.30.30.31.00.50.4-0.20.2-0.5
Locomotion distance, session 11.62.05.9-2.21.92.1-1.4-0.4-1.50.31.2-2.02.4-0.2-0.2-0.21.81.51.1-0.71.1-1.2
Locomotion velocity, session 20.10.20.6-0.30.10.2-0.00.2-0.2-0.3-0.6-0.3-0.20.40.40.40.7-0.20.80.20.6-0.6
Locomotion distance, session 21.62.35.9-2.11.81.9-1.5-0.6-1.60.40.6-1.82.2-0.2-0.2-0.22.41.02.3-1.01.4-1.8
Locomotion velocity, session 30.20.31.7-0.1-0.10.10.20.50.1-0.5-0.1-0.20.20.60.60.6-0.40.2-1.30.9-0.50.2
Locomotion distance, session 31.01.11.9-1.21.21.2-1.1-1.3-1.21.41.0-1.30.9-1.2-1.2-1.20.81.20.3-0.60.4-0.4
Stereotopy head waving bouts, day 30.60.72.5-0.20.4-0.30.80.81.0-1.0-0.31.00.40.80.80.80.2-0.7-0.91.0-1.61.5
Stereotopy head waving duration, day 30.60.72.80.10.0-0.40.80.51.0-0.7-0.11.10.10.60.60.6-0.1-0.5-1.11.1-1.41.7
Locomotion velocity, session 71.41.52.6-1.51.41.4-1.4-1.1-1.31.51.3-1.01.6-1.4-1.4-1.41.31.30.6-0.50.1-0.0
Locomotion distance, session 70.50.61.6-0.80.60.9-1.2-0.3-1.20.60.2-1.11.1-0.5-0.5-0.50.90.51.0-0.41.3-0.5
Stereotopy head waving bouts, day 70.30.31.1-0.60.60.5-0.1-0.70.10.60.70.10.2-0.7-0.7-0.7-0.00.6-1.00.2-1.00.7
Stereotopy head waving duration, day 70.20.31.5-0.00.0-0.20.5-0.40.60.20.40.7-0.3-0.3-0.3-0.3-0.20.0-1.00.4-1.20.8
Locomotion velocity, session 80.20.31.4-0.60.50.6-0.5-0.0-0.40.01.2-0.50.7-0.1-0.1-0.1-0.10.9-0.70.0-0.40.1
Locomotion distance, session 80.50.72.1-1.31.11.3-0.9-0.2-1.00.31.0-1.21.4-0.2-0.2-0.20.61.10.0-0.60.3-0.9
Degree of sensitization distance0.90.92.31.1-1.1-0.80.51.50.5-1.4-1.10.5-0.41.31.31.3-0.9-0.9-0.30.70.50.2
Degree of sensitization stereotypy0.20.20.5-0.10.20.1-0.0-0.70.10.60.40.1-0.4-0.7-0.7-0.7-0.40.4-0.7-0.2-0.70.1
Conditioned locomotion1.21.52.5-1.41.01.3-1.1-1.5-1.11.41.6-1.10.9-1.3-1.3-1.31.51.21.0-1.10.1-0.4
Cocaine response after cond. corrected0.50.51.61.3-1.1-1.10.7-0.20.80.1-0.61.1-1.2-0.0-0.0-0.0-0.9-0.7-0.10.1-0.80.4
Cocaine response after cond. not corrected0.50.51.51.2-1.1-1.00.70.10.8-0.2-0.61.0-1.10.30.30.3-0.9-0.7-0.20.1-0.70.4
Cocaine response before conditioning0.20.20.5-0.20.20.00.30.70.4-0.7-0.40.2-0.00.70.70.70.6-0.40.20.20.20.0
Saline control response0.20.20.8-0.90.70.7-0.20.2-0.2-0.30.0-0.50.60.40.40.40.70.2-0.20.30.2-0.2
Bone: connectivity density3.35.28.2-2.42.92.2-2.3-2.7-2.12.82.2-1.42.0-2.7-2.7-2.72.32.02.6-2.11.3-1.0
Bone: cortical apparent density0.10.10.70.1-0.2-0.20.20.40.2-0.1-0.40.2-0.20.30.30.30.4-0.4-0.10.5-0.50.8
Bone: cortical area2.13.25.4-2.02.21.8-1.9-2.3-1.62.11.5-1.11.8-1.9-1.9-1.91.91.41.9-1.70.9-1.1
Bone: cortical porosity1.01.16.0-1.20.90.6-0.5-1.0-0.50.90.1-0.50.5-0.7-0.7-0.72.4-0.12.5-1.00.7-0.7
Bone: cortical porosity0.80.95.2-0.80.80.3-0.3-1.0-0.20.9-0.1-0.10.1-0.7-0.7-0.72.0-0.42.3-1.10.4-0.6
Bone: cortical thickness0.71.12.2-1.21.41.0-1.1-1.4-0.81.30.5-0.41.0-1.1-1.1-1.11.50.51.5-1.20.4-0.5
Bone: cortical thickness1.41.76.2-1.52.11.0-1.1-1.2-0.91.3-0.0-0.10.9-1.1-1.1-1.12.2-0.02.5-1.20.8-1.0
Bone: cortical tissue density0.20.21.00.3-0.4-0.40.40.50.4-0.3-0.60.4-0.40.40.40.40.2-0.5-0.30.6-0.71.0
Condit. Reinf. active minus inactive responses0.20.20.60.1-0.00.2-0.3-0.5-0.10.40.80.40.4-0.5-0.5-0.5-0.80.7-0.4-0.6-0.4-0.5
Condit. Reinf. active-inactive response ratio1.01.02.90.10.20.4-0.9-1.3-0.61.31.7-0.00.5-1.4-1.4-1.4-1.31.5-0.7-1.10.1-0.6
Condit. Reinf. active responses0.30.31.5-0.70.70.8-0.70.0-0.7-0.10.6-0.41.20.00.00.00.20.70.1-0.40.3-0.6
Condit. Reinf. inactive responses0.70.83.0-1.41.11.0-0.50.7-0.5-0.8-0.3-0.71.50.80.80.81.7-0.10.90.30.50.1
Incentive salience index mean0.10.10.30.1-0.20.10.10.40.2-0.60.10.40.40.50.50.5-0.30.1-0.5-0.0-0.5-0.4
Condit. Reinf. lever presses0.40.51.7-0.80.40.8-0.40.8-0.4-1.00.0-0.71.30.90.90.90.90.20.4-0.10.2-0.8
Condit. Reinf. active minus inactive responses0.20.20.6-0.1-0.1-0.00.00.7-0.1-0.8-0.7-0.30.30.70.70.70.5-0.50.20.40.5-0.5
Condit. Reinf. active-inactive response ratio0.60.61.40.3-0.6-0.40.31.10.1-1.2-1.0-0.00.11.21.21.20.6-1.00.50.70.8-0.5
Condit. Reinf. active responses0.40.61.60.4-0.4-0.40.41.30.3-1.2-1.1-0.0-0.31.21.21.2-0.4-0.8-0.70.80.0-0.1
Condit. Reinf. inactive responses0.20.21.50.4-0.0-0.20.30.30.3-0.1-0.20.2-0.30.20.20.2-1.10.1-1.20.4-0.70.5
Condit. Reinf. lever presses1.52.03.81.3-1.2-1.21.31.71.3-1.7-1.20.9-0.71.71.71.7-1.5-1.1-1.91.6-1.21.3
Condit. Reinf. lever reinforcers received0.40.61.20.6-0.5-0.70.61.10.5-1.0-1.10.3-0.51.01.01.0-0.6-0.9-0.80.8-0.30.1
Conditioned reinforcement - actives2.12.13.91.2-0.7-1.41.91.52.0-1.6-1.62.0-0.81.61.61.6-0.8-1.7-1.01.2-1.21.2
Conditioned reinforcement - inactives0.20.20.60.3-0.3-0.30.60.50.4-0.5-0.50.2-0.50.50.50.5-0.3-0.4-0.00.5-0.80.3
Conditioned locomotion1.31.63.11.0-1.2-1.11.61.31.4-1.3-1.21.0-1.01.31.31.3-1.0-1.1-1.61.8-0.81.0
Patch foraging indifference point 0 sec0.20.30.8-0.30.40.5-0.20.9-0.4-0.90.1-0.80.50.80.80.8-0.30.4-0.40.50.7-0.4
Patch foraging indifference point AUC0.20.31.2-0.4-0.30.2-0.3-0.0-0.20.40.8-0.30.6-0.5-0.5-0.50.80.3-0.30.7-0.51.1
Delay disc. indifference point, 0s delay0.50.61.6-1.11.30.9-0.70.1-0.6-0.3-0.2-0.91.10.30.30.30.50.21.0-0.90.8-1.2
Delay disc. indifference point, 16s delay1.01.02.60.7-1.0-0.50.91.60.9-1.5-1.00.60.11.61.61.6-0.3-0.7-0.41.0-0.4-0.0
Delay disc. indifference point, 2s delay0.70.82.8-0.60.61.0-1.0-0.6-1.00.50.6-1.30.9-0.5-0.5-0.5-0.41.10.3-1.01.2-1.7
Delay disc. indifference point, 24s delay2.72.65.11.8-2.2-1.51.61.81.5-1.9-1.20.9-1.21.81.81.8-2.0-1.2-2.31.5-1.10.7
Delay disc. indifference point, 4s delay2.22.36.5-1.71.81.9-1.8-0.8-1.70.60.7-2.01.9-0.7-0.7-0.70.81.41.4-1.61.7-2.5
Delay disc. indifference point, 8s delay0.40.42.6-0.1-0.20.5-0.70.3-0.8-0.20.1-1.00.7-0.1-0.1-0.1-0.30.60.1-0.21.2-1.6
Indifference point function ln k0.30.41.9-0.10.80.1-0.00.1-0.2-0.2-0.9-0.2-0.70.10.10.10.1-0.31.3-0.80.8-1.4
Indifference point function log k0.30.41.9-0.10.80.1-0.00.1-0.2-0.2-0.9-0.2-0.70.10.10.10.1-0.31.3-0.80.8-1.4
Patch foraging total patch changes 0 sec0.30.51.3-0.50.50.7-0.31.2-0.5-1.10.1-1.00.71.01.01.0-0.10.5-0.30.40.9-0.6
Patch foraging total patch changes 12 sec0.00.10.4-0.10.10.1-0.20.1-0.1-0.1-0.0-0.20.30.00.00.00.40.10.60.00.4-0.3
Patch foraging total patch changes 18 sec0.40.53.3-1.00.70.9-0.60.5-0.5-0.30.6-0.71.80.30.30.31.10.50.00.40.10.1
Patch foraging total patch changes 24 sec2.73.36.4-1.81.52.0-2.2-1.5-2.11.72.5-1.92.5-1.7-1.7-1.71.02.30.9-1.51.5-1.3
Patch foraging total patch changes 6 sec0.71.12.9-0.60.61.2-1.3-0.6-1.30.71.5-1.41.5-0.9-0.9-0.9-0.61.7-0.3-0.51.4-0.5
Patch foraging time to switch 0 sec0.10.20.60.6-0.4-0.40.2-0.40.30.2-0.20.6-0.3-0.1-0.1-0.1-0.6-0.10.5-0.60.1-0.8
Patch foraging water rate 0 sec0.40.62.30.1-0.4-0.10.51.30.3-1.1-0.3-0.2-0.31.01.01.0-0.4-0.2-1.51.3-0.81.1
Patch foraging water rate 12 sec2.74.17.1-2.62.72.5-2.2-1.7-2.11.92.6-2.22.5-1.9-1.9-1.91.72.40.7-1.60.5-1.0
Patch foraging water rate 18 sec2.02.75.1-2.01.82.1-2.0-1.4-2.11.21.6-2.31.7-1.2-1.2-1.21.22.01.1-1.31.5-1.6
Patch foraging water rate 24 sec3.04.26.8-2.62.52.4-2.1-1.9-2.12.02.1-2.32.0-1.9-1.9-1.92.12.11.7-1.81.2-1.7
Patch foraging water rate 6 sec0.20.41.6-1.11.00.7-0.30.2-0.2-0.20.2-0.30.90.20.20.21.30.1-0.20.5-0.70.6
Seeking ratio, delayed vs. immediate footshock2.63.04.4-1.91.71.9-2.0-1.5-2.01.71.6-2.11.7-1.7-1.7-1.71.41.71.7-1.61.6-1.4
Distance traveled before self-admin0.40.51.5-0.71.20.8-0.7-0.7-0.60.60.6-0.21.1-0.6-0.6-0.60.10.70.3-0.90.7-0.5
Distance traveled after self-admin0.20.31.2-1.01.10.7-0.30.0-0.3-0.10.3-0.41.00.00.00.00.80.20.2-0.30.00.1
Extensor digitorum longus weight4.718.629.8-5.55.25.3-4.8-3.5-4.63.54.4-4.95.0-3.4-3.4-3.44.64.44.1-3.73.5-3.4
Bone: elastic displacement0.50.62.6-0.90.70.6-0.30.4-0.5-0.6-0.2-0.70.80.70.70.71.6-0.11.5-0.10.6-0.4
Bone: elastic work0.50.62.9-1.01.10.8-0.7-0.4-0.60.20.1-0.40.7-0.1-0.1-0.11.60.11.7-0.60.5-0.8
Bone: endosteal estimation0.61.31.9-1.11.01.1-1.4-1.3-1.41.11.4-1.10.9-1.4-1.4-1.40.71.20.6-0.80.8-0.8
Bone: endosteal perimeter1.42.84.7-1.91.72.0-2.0-1.7-2.01.52.2-1.81.9-1.7-1.7-1.71.32.01.1-1.01.2-0.9
Epididymis fat weight0.20.51.2-0.30.00.5-0.8-0.5-1.00.70.8-1.1-0.0-0.7-0.7-0.7-0.30.80.1-0.71.1-0.9
Delta time in closed arm before/after self-admin1.01.02.7-1.21.31.2-1.20.1-1.2-0.00.6-1.21.70.00.00.01.10.71.4-1.01.2-1.2
Delta time in open arm before/after self-admin3.63.57.72.8-2.5-2.72.00.52.2-0.4-1.72.7-2.80.50.50.5-2.2-1.8-1.71.3-1.51.7
Diff in mean of infusions in LGA sessions1.51.64.81.9-2.1-1.41.30.91.1-0.9-1.10.8-1.50.90.90.9-2.2-0.7-1.61.1-0.70.6
Delay discount exponential model param0.50.62.60.10.3-0.50.4-1.00.50.90.31.0-0.8-0.8-0.8-0.80.4-0.30.1-0.1-1.11.6
Extinction: sum of active levers before priming0.30.31.60.3-0.6-0.20.20.20.2-0.30.70.1-0.00.10.10.1-0.60.4-1.31.0-1.11.0
Active lever presses in extinction session 60.40.30.7-0.1-0.20.2-0.7-0.8-0.60.80.7-0.30.7-0.8-0.8-0.80.10.50.4-0.40.7-0.2
Bone: final force2.44.06.8-1.82.11.8-2.3-2.6-2.02.41.7-1.51.7-2.4-2.4-2.41.21.81.8-2.11.8-1.3
Bone: final moment2.94.77.5-1.92.32.0-2.5-2.7-2.32.61.8-1.81.8-2.5-2.5-2.51.31.92.1-2.32.2-1.6
Food consumed during 24 hour testing period1.51.83.50.8-0.8-1.21.51.21.5-1.2-1.71.5-1.11.21.21.20.2-1.6-0.61.8-1.61.9
Glucose0.40.62.00.0-0.50.20.11.4-0.2-1.3-0.6-0.60.61.21.21.2-0.2-0.1-0.41.01.1-0.3
Heart weight2.84.07.1-2.02.72.0-2.3-2.2-2.32.42.0-1.81.7-2.3-2.3-2.30.82.00.6-2.31.4-1.4
Delay discount hyperbolic model param0.70.74.10.4-0.1-0.90.8-0.60.90.5-0.11.4-1.1-0.4-0.4-0.40.4-0.7-0.20.4-1.52.0
Intermittent access intake day 1-15 change0.40.40.6-0.80.70.6-0.4-0.7-0.40.70.7-0.20.6-0.7-0.7-0.70.70.50.6-0.7-0.30.4
Intermittent access intake escalation0.60.61.0-1.00.90.8-0.7-0.8-0.70.80.8-0.50.8-0.8-0.8-0.80.80.60.9-1.00.20.0
Intermittent access intake escalation 20.80.81.8-1.00.61.1-1.1-0.4-1.20.41.1-1.31.3-0.4-0.4-0.40.61.10.7-1.00.7-0.7
Intermitt. access day 1 inactive lever presses2.42.64.9-1.61.61.8-1.7-1.8-1.61.82.2-1.51.7-1.8-1.8-1.80.32.10.4-1.80.5-1.1
Intermitt. access day 15 inactive lever presses2.02.24.5-1.41.01.5-1.4-2.0-1.52.02.1-1.51.3-2.0-2.0-2.00.02.00.3-1.2-0.0-0.4
Intermitt. access escalation Index0.40.31.10.6-0.2-0.40.1-0.70.20.70.00.3-0.9-0.7-0.7-0.7-1.10.2-0.7-0.1-0.10.4
Intermittent access day 1 total infusions0.91.13.31.6-1.4-1.21.20.71.2-0.7-0.81.3-1.00.70.70.7-1.8-0.7-1.30.6-0.50.5
Intermittent access day 15 total infusions0.20.20.80.5-0.5-0.20.2-0.60.30.60.30.6-0.1-0.6-0.6-0.6-0.90.2-0.3-0.4-0.10.4
Intermittent access terminal intake (last 3 days)0.30.40.9-0.0-0.00.2-0.2-1.0-0.11.00.70.20.3-1.0-1.0-1.0-0.60.6-0.6-0.3-0.40.4
Intermittent access total infusions0.40.41.91.0-0.8-0.70.5-0.50.60.50.01.0-0.6-0.5-0.5-0.5-1.4-0.0-0.9-0.0-0.30.5
Intermittent access day 1 locomotion1.01.01.81.2-1.3-1.01.41.01.3-1.0-0.91.1-0.71.01.01.0-1.0-0.8-0.91.1-0.60.6
Intermittent access day 15 total locomotion1.41.62.81.3-1.5-1.41.61.01.5-1.0-1.31.7-1.21.01.01.0-0.8-1.4-1.11.1-1.31.2
Intermittent access total locomotion1.21.42.51.4-1.6-1.31.50.81.4-0.8-1.01.5-1.10.80.80.8-1.5-0.9-1.41.2-1.01.0
Intermittent access standard deviation2.12.33.2-1.51.51.5-1.5-1.8-1.51.81.5-1.31.3-1.8-1.8-1.81.01.61.5-1.70.8-1.1
Left kidney weight2.36.49.4-2.82.92.9-3.0-2.5-3.12.72.6-2.82.3-2.7-2.7-2.71.52.71.2-2.02.2-1.7
Right kidney weight2.67.310.1-3.03.13.0-3.2-2.8-3.22.92.6-2.92.3-2.9-2.9-2.91.72.81.7-2.22.4-2.1
Cocaine induced anxiety0.91.03.2-0.2-0.30.10.61.80.3-1.8-1.0-0.60.01.81.81.80.1-0.6-0.21.00.3-0.5
Post-drug Anxiety0.20.20.6-0.80.60.6-0.10.3-0.3-0.40.2-0.70.50.40.40.40.70.30.20.2-0.1-0.4
Baseline Anxiety1.31.43.5-0.10.8-0.0-0.1-1.90.31.81.11.1-0.1-1.8-1.8-1.8-0.10.6-0.6-0.5-1.81.5
Tail length0.51.65.1-1.51.30.9-1.0-1.8-0.81.61.3-0.41.0-1.6-1.6-1.62.30.71.5-0.4-0.50.5
Length with tail1.24.37.3-2.72.22.3-2.3-2.2-2.12.42.6-1.92.1-2.4-2.4-2.42.52.01.1-1.10.30.1
Length without tail1.02.14.1-1.81.41.9-1.7-1.0-1.81.31.9-2.01.4-1.4-1.4-1.40.81.9-0.3-1.00.9-0.4
Times rat made contact with spout0.30.41.2-0.00.10.00.20.90.0-0.9-1.1-0.3-0.20.90.90.9-0.2-0.5-0.51.00.7-0.1
Lifetime Intake0.30.31.40.8-0.6-0.60.5-0.60.50.6-0.00.9-0.5-0.6-0.6-0.6-1.20.0-0.7-0.1-0.30.4
Liver weight, left2.74.37.5-2.21.52.6-2.5-1.5-2.71.62.2-2.72.3-1.6-1.6-1.61.52.71.5-1.12.6-2.3
Liver weight, right0.81.44.3-0.0-0.6-0.20.81.80.7-1.7-0.40.30.11.71.71.70.3-0.5-1.12.1-1.11.5
Locomotor activity0.10.21.3-0.81.10.5-0.3-0.3-0.3-0.1-0.2-0.20.50.10.10.10.9-0.10.6-0.20.2-0.4
Locomotor testing distance0.71.25.0-1.82.21.4-0.8-0.4-0.6-0.10.3-0.71.70.00.00.01.90.31.6-0.90.5-0.9
Locomotor testing rearing0.61.03.3-1.21.71.0-0.9-0.7-0.80.4-0.3-0.71.0-0.4-0.4-0.40.90.21.4-1.41.3-1.8
Locomotion in novel chamber2.63.25.3-1.41.41.9-1.9-1.9-2.01.61.7-1.91.5-1.8-1.8-1.80.62.11.3-2.12.3-2.3
Locomotion in novel chamber post-restriction0.30.31.50.8-0.5-0.60.20.60.1-0.5-0.70.3-0.90.50.50.5-1.2-0.5-0.3-0.40.5-0.7
Fecal boli incidents, locomotor time 10.50.51.20.00.30.4-1.1-0.2-1.00.50.9-0.50.8-0.6-0.6-0.6-0.90.90.1-1.01.1-0.7
Change in fecal boli incidents, locomotor task0.70.73.6-1.00.70.50.30.80.1-0.9-1.0-0.60.21.01.01.01.9-0.70.90.70.1-0.2
Time >=10cm from walls, locomotor time 10.70.72.3-0.80.31.2-1.0-0.1-1.00.21.4-1.41.5-0.2-0.2-0.2-0.01.5-0.4-0.20.5-0.5
Bouts of movement, locomotor time 11.01.12.91.4-1.7-1.40.90.90.7-1.1-1.50.8-1.51.01.01.0-0.7-1.4-0.50.70.40.2
Total resting periods, locomotor time 11.41.53.21.4-1.8-1.51.21.30.9-1.4-1.80.9-1.51.31.31.3-0.4-1.7-0.40.90.20.3
Rest time, locomotor task time 10.20.32.4-0.30.0-0.10.20.40.1-0.3-0.60.1-0.30.10.10.11.5-0.71.10.00.3-0.2
Distance moved, locomotor task time 11.11.22.6-0.81.41.0-1.1-1.6-1.11.41.2-0.80.8-1.3-1.3-1.3-0.31.30.4-1.10.2-0.5
Vertical activity count, locomotor time 10.60.61.9-0.31.30.8-0.6-0.9-0.50.80.9-0.10.8-0.6-0.6-0.6-1.41.2-0.5-0.7-0.2-0.1
Time >=10cm from walls, locomotor time 20.60.61.4-0.10.4-0.20.80.90.9-1.0-0.80.8-0.11.11.11.10.5-0.8-0.01.2-1.00.8
Bouts of movement, locomotor time 21.21.34.71.4-1.2-1.10.81.00.8-1.0-0.81.0-1.10.90.90.9-2.2-0.6-2.00.7-0.80.6
Total resting periods, locomotor time 21.61.74.01.5-1.4-1.31.01.41.0-1.4-1.11.2-1.21.31.31.3-2.0-0.9-2.01.0-0.80.8
Rest time, locomotor task time 20.10.10.4-0.4-0.00.3-0.30.0-0.30.20.5-0.40.3-0.3-0.3-0.30.60.3-0.50.2-0.20.6
Distance moved, locomotor task time 20.10.10.50.30.0-0.30.1-0.70.00.50.00.3-0.6-0.4-0.4-0.4-0.6-0.00.4-0.20.2-0.1
Vertical activity count, locomotor time 20.30.31.4-0.10.70.4-0.5-0.3-0.40.50.7-0.10.5-0.3-0.3-0.3-1.20.8-0.1-0.90.6-0.4
Light reinforcement 10.81.44.0-2.01.81.8-1.2-0.6-1.20.51.0-1.61.8-0.4-0.4-0.41.61.20.8-0.40.3-1.1
Light reinforcement 20.10.20.4-0.0-0.6-0.10.20.40.2-0.6-0.3-0.1-0.10.60.60.60.1-0.2-0.30.6-0.50.3
Bone: marrow area0.51.11.7-1.10.91.1-1.3-1.2-1.31.01.3-1.10.9-1.3-1.3-1.30.71.10.6-0.70.8-0.9
Bone: maximum diameter0.40.71.3-1.00.80.8-0.9-1.1-0.70.91.1-0.41.2-1.0-1.0-1.00.90.70.5-0.30.2-0.3
Bone: maximum force3.76.411.3-2.42.82.4-2.9-3.4-2.63.32.6-1.82.2-3.2-3.2-3.21.42.51.7-2.41.8-1.2
Bone: maximum moment4.37.412.3-2.52.92.6-3.1-3.5-2.83.52.7-2.12.2-3.3-3.3-3.31.52.72.0-2.62.2-1.5
Mean time between licks in bursts1.82.54.52.1-2.1-1.81.41.91.4-1.7-1.81.3-1.31.71.71.7-2.0-1.5-1.30.9-0.90.1
Mean num. licks in bursts0.30.41.0-1.00.90.8-0.6-0.4-0.70.20.1-0.80.6-0.2-0.2-0.20.80.50.4-0.10.6-1.0
Cd content in liver1.01.12.70.5-0.4-0.60.91.60.8-1.5-0.70.6-0.31.51.51.5-0.5-0.8-1.31.2-0.81.0
Co content in liver0.30.32.20.10.3-0.2-0.3-0.1-0.30.1-0.70.30.0-0.0-0.0-0.00.5-0.51.5-0.71.0-0.9
Cu content in liver2.32.86.6-2.02.01.8-2.0-0.9-2.10.91.0-1.81.7-1.0-1.0-1.02.21.22.6-1.22.3-1.4
Fe content in liver1.51.76.8-1.81.91.2-0.8-1.4-0.71.10.6-0.60.8-1.0-1.0-1.02.60.32.5-1.40.5-0.8
K content in liver1.71.76.01.2-1.5-1.41.11.01.1-0.6-0.31.2-1.30.50.50.5-1.0-0.8-2.22.0-1.82.5
Mg content in liver0.40.52.90.4-0.4-0.60.30.20.40.10.40.5-0.6-0.2-0.2-0.2-0.4-0.2-1.30.8-1.21.7
Mn content in liver0.30.31.40.8-1.2-0.70.40.40.3-0.2-0.10.6-0.50.20.20.2-0.4-0.4-0.60.7-0.60.6
Na content in liver1.81.94.0-1.72.01.6-1.6-1.0-1.51.51.2-1.31.5-1.6-1.6-1.61.01.30.6-0.51.10.2
Rb content in liver0.81.02.61.6-1.3-1.30.61.00.5-1.1-1.20.8-1.30.90.90.9-1.4-1.0-0.10.20.6-0.1
Se content in liver0.81.02.5-0.71.20.7-0.8-1.3-0.71.51.6-0.20.4-1.5-1.5-1.5-0.21.1-0.0-0.9-0.2-0.0
Sr content in liver2.72.54.0-0.80.91.4-1.8-1.8-1.91.81.7-1.51.4-1.8-1.8-1.8-0.42.00.6-1.71.8-1.5
Zn content in liver0.50.61.8-0.90.80.9-0.7-0.2-0.8-0.00.5-0.80.9-0.1-0.1-0.11.10.51.3-0.50.9-1.3
Bone: minimum diameter0.91.63.3-1.31.21.4-1.5-1.8-1.21.41.2-1.01.1-1.6-1.6-1.60.71.30.7-0.90.6-1.2
Time in familiar zone, hab. session 11.41.33.1-1.51.81.1-1.1-1.3-0.91.31.5-0.71.2-1.3-1.3-1.31.21.00.5-0.90.20.4
Time in novel zone, hab. session 11.51.52.81.1-1.2-1.01.11.71.0-1.6-1.50.8-0.81.61.61.6-0.9-1.2-0.91.3-0.60.6
Total zone transitions, hab. session 10.30.41.9-1.00.80.7-0.5-0.3-0.50.00.0-0.60.70.20.20.21.40.10.9-0.20.5-0.3
Total locomotion distance, hab. session 10.91.36.7-2.21.91.6-0.90.0-0.9-0.20.7-1.31.60.10.10.12.60.60.50.60.00.7
Locomotion velocity, hab. session 10.71.04.9-1.91.61.4-0.9-0.1-0.9-0.00.5-1.21.3-0.0-0.0-0.02.20.60.60.40.20.2
Time in familiar zone, hab. session 20.50.61.6-0.50.40.8-0.9-0.4-1.00.21.3-1.21.1-0.2-0.2-0.2-0.41.1-0.2-0.61.1-0.1
Time in novel zone, hab. session 20.40.41.30.4-0.0-0.70.7-0.10.80.3-1.01.2-1.1-0.3-0.3-0.30.4-0.90.50.2-0.9-0.1
Total zone transitions, hab. session 21.41.84.5-1.91.51.7-1.20.0-1.4-0.00.5-1.91.60.30.30.32.00.91.7-0.71.4-2.1
Total locomotion distance, hab. session 21.41.98.5-2.52.01.9-0.90.8-1.1-0.70.4-1.71.90.70.70.72.90.61.00.80.5-0.4
Locomotion velocity, hab. session 21.21.77.6-2.31.81.7-0.80.9-0.9-0.80.2-1.61.80.80.80.82.80.40.90.90.4-0.3
Novel to familiar place preference ratio0.60.61.9-0.10.50.1-0.3-1.4-0.21.40.1-0.1-0.6-1.3-1.3-1.30.00.30.3-0.8-0.1-1.0
Novelty place preference0.50.51.30.30.0-0.3-0.0-1.10.01.1-0.30.2-1.1-1.1-1.1-1.1-0.3-0.00.2-0.6-0.1-1.0
Time in novel zone, NPP test0.40.51.30.20.2-0.2-0.0-1.10.01.1-0.20.2-1.0-1.1-1.1-1.1-0.2-0.00.2-0.6-0.2-1.0
Total zone transitions, NPP test0.50.71.9-1.10.81.0-0.40.6-0.4-0.7-0.2-0.91.20.90.90.91.40.21.0-0.20.2-1.3
Total locomotion distance, NPP test0.91.24.3-1.81.31.6-0.90.7-1.0-0.50.3-1.61.60.50.50.52.10.70.90.30.5-0.8
Locomotion velocity, NPP test0.81.13.8-1.81.21.5-0.90.6-1.0-0.40.3-1.71.60.50.50.52.00.70.90.10.6-0.9
Intraocular pressure0.81.12.61.1-1.3-1.11.21.20.9-1.2-1.60.7-1.31.31.31.3-0.4-1.30.10.70.3-0.9
Delta distance traveled before/after self-admin0.20.31.4-0.70.30.20.30.50.2-0.50.1-0.20.40.50.50.51.2-0.30.10.5-0.80.8
Delta ambulatory time before/after self-admin1.01.13.3-0.30.0-0.51.11.11.2-1.1-0.50.8-0.21.11.11.11.3-1.2-0.20.9-1.81.7
Parametrial fat weight0.51.02.9-1.40.91.3-0.80.6-1.1-0.40.7-1.71.00.50.50.51.30.90.90.41.6-0.6
Pavlov. Cond. lever latency0.30.41.4-0.4-0.00.2-0.3-0.8-0.31.01.2-0.30.2-0.9-0.9-0.90.70.60.10.1-0.10.8
Pavlov. Cond. magazine entry latency0.30.42.5-0.30.50.4-0.20.7-0.2-0.9-0.7-0.30.40.70.70.70.2-0.11.0-0.21.0-1.6
Pavlov. Cond. change in total contacts0.30.31.9-0.30.70.5-0.4-0.2-0.5-0.1-0.2-0.30.60.00.00.0-0.00.20.8-1.00.6-1.4
Pavlov. Cond. index score0.30.32.4-0.40.70.5-0.20.3-0.3-0.6-0.5-0.30.50.40.40.40.00.10.7-0.50.7-1.6
Pavlov. Cond. latency score0.30.42.1-0.30.60.5-0.10.6-0.2-0.8-0.7-0.30.50.70.70.7-0.0-0.00.6-0.30.6-1.5
Pavlov. Cond. lever contacts0.40.41.50.30.1-0.10.21.00.1-1.1-1.20.10.11.01.01.0-0.5-0.50.10.00.4-1.0
Pavlov. Cond. magazine entry number0.40.53.80.3-0.5-0.60.4-0.30.50.50.30.6-0.6-0.3-0.3-0.30.3-0.3-0.70.8-1.42.0
Pavlov. Cond. intertrial magazine entries0.91.13.20.8-0.3-1.31.20.31.3-0.6-1.01.7-1.00.60.60.60.2-1.6-0.30.9-1.81.7
Pavlov. Cond. lever-magazine prob. diff.0.30.42.6-0.40.80.5-0.30.3-0.3-0.6-0.5-0.30.50.40.40.40.10.10.8-0.60.7-1.6
Pavlov. Cond. response bias0.30.32.1-0.10.30.2-0.00.7-0.1-0.9-0.7-0.20.30.70.70.7-0.2-0.20.5-0.20.8-1.5
Pavlov. Cond. lever latency1.41.83.2-1.31.11.2-1.2-1.6-1.21.51.5-0.90.9-1.6-1.6-1.61.61.31.8-1.40.9-1.2
Pavlov. Cond. magazine entry latency0.91.01.81.3-1.1-1.31.20.71.2-0.7-1.31.3-1.10.70.70.7-0.8-1.3-0.60.8-1.10.8
Pavlov. Cond. change in total contacts3.04.16.62.0-2.0-2.12.22.22.1-2.3-2.61.8-1.82.32.32.3-1.3-2.4-1.52.1-1.51.5
Pavlov. Cond. index score2.32.94.21.6-1.6-1.81.81.81.8-1.8-2.11.5-1.51.81.81.8-1.1-2.0-1.41.8-1.51.5
Pavlov. Cond. latency score2.53.14.21.6-1.6-1.81.91.81.9-1.8-2.01.6-1.41.81.81.8-1.0-2.1-1.52.0-1.71.8
Pavlov. Cond. lever contacts0.81.11.90.9-0.7-0.80.91.40.8-1.4-1.00.5-0.41.41.41.4-1.1-0.9-1.41.2-0.71.0
Pavlov. Cond. magazine entry number1.41.73.1-1.41.41.6-1.4-1.3-1.41.31.8-1.21.3-1.3-1.3-1.30.91.70.8-1.11.1-0.7
Pavlov. Cond. intertrial magazine entries0.10.10.30.0-0.1-0.10.50.50.5-0.5-0.20.4-0.40.50.50.50.3-0.30.00.6-0.10.3
Pavlov. Cond. lever-magazine prob. diff.2.43.14.61.7-1.6-1.91.91.81.9-1.8-2.11.7-1.61.91.91.9-1.0-2.1-1.31.8-1.71.5
Pavlov. Cond. response bias0.81.11.81.3-1.2-1.10.91.20.8-1.2-1.30.6-0.81.21.21.2-1.3-1.0-1.00.8-0.40.4
Time in closed arm before self-admin0.80.91.8-1.00.90.9-0.9-1.2-1.01.00.8-1.10.4-1.0-1.0-1.00.70.70.9-1.31.0-1.0
Time in closed arm after self-admin3.63.76.4-2.32.12.1-2.1-1.6-2.11.41.4-2.12.1-1.4-1.4-1.42.31.42.5-2.32.0-2.0
Time in open arm before self-admin0.50.51.5-1.10.71.1-0.60.1-0.7-0.10.9-1.11.20.00.00.01.10.8-0.10.20.1-0.2
Time in open arm after self-admin0.50.51.41.1-1.2-0.90.70.50.7-0.3-0.60.7-1.00.40.40.4-0.7-0.5-0.91.0-0.60.5
Bone: periosteal estimation1.22.54.1-1.71.71.6-1.8-2.0-1.61.81.6-1.21.4-1.8-1.8-1.81.51.41.2-1.20.9-0.9
Bone: periosteal perimeter1.82.94.0-2.01.81.9-2.0-2.0-1.81.72.0-1.51.8-1.7-1.7-1.71.61.81.5-1.31.1-1.1
Bone: post-yield work3.24.47.5-2.12.42.1-2.3-2.6-2.02.72.5-1.32.0-2.7-2.7-2.71.22.30.8-1.60.8-0.2
Progressive ratio test 1 active lever presses0.60.61.61.1-0.8-0.90.8-0.00.90.1-0.71.3-0.7-0.1-0.1-0.1-1.1-0.6-1.00.7-0.71.0
Progressive ratio test 1 breakpoint0.60.61.51.0-0.6-0.90.8-0.20.80.2-0.61.2-0.8-0.2-0.2-0.2-1.1-0.6-1.10.7-0.91.2
Progressive ratio test 1 inactive lever presses1.21.33.0-0.40.31.1-1.2-0.7-1.30.71.4-1.41.2-0.7-0.7-0.7-1.31.7-0.2-1.31.5-1.6
Progressive ratio test 2 active lever presses0.70.72.31.0-0.6-0.91.10.11.2-0.2-0.51.5-0.60.20.20.2-1.1-0.6-1.00.6-1.11.2
Progressive ratio test 2 breakpoint1.01.13.51.1-0.7-1.21.40.31.5-0.3-0.61.9-0.90.30.30.3-1.1-0.9-1.20.8-1.61.6
Progressive ratio test 2 inactive lever presses0.70.84.11.3-1.1-1.00.90.50.8-0.5-0.80.9-1.10.50.50.5-2.0-0.5-1.10.6-0.60.4
Incentive Sensitization - Responses3.33.36.31.7-1.6-2.22.11.22.2-1.3-1.82.5-2.01.31.31.3-0.9-2.2-1.31.8-2.32.4
Incentive Sensitization - Breakpoint2.82.85.41.6-1.5-2.01.91.12.0-1.2-1.52.3-1.81.21.21.2-0.9-2.0-1.31.8-2.32.3
Sum of active levers in priming session hrs 5-61.01.02.61.0-0.8-0.80.6-0.90.70.80.31.2-0.9-0.8-0.8-0.8-1.20.0-1.60.8-1.51.6
Progressive ratio0.50.62.31.1-1.5-0.80.70.00.7-0.30.10.6-0.60.20.20.2-1.1-0.1-1.10.6-1.30.6
Food seeking constrained by brief footshock2.02.44.4-1.81.41.5-1.8-1.6-1.51.52.1-1.31.8-1.7-1.7-1.72.01.51.4-1.20.7-0.7
Seeking ratio, punishment vs. effort3.44.28.2-2.72.72.2-2.2-1.8-2.11.91.8-1.82.1-1.9-1.9-1.92.91.52.3-1.71.7-1.2
Retroperitoneal fat weight0.72.25.8-0.70.71.3-1.8-1.1-2.11.31.3-2.10.7-1.3-1.3-1.3-0.91.90.3-1.42.4-2.1
Reaction time number correct0.50.81.51.0-0.9-0.90.90.70.8-0.6-0.80.6-1.00.70.70.7-1.2-0.7-1.20.9-1.10.8
Reaction time mean minus median0.20.21.30.1-0.5-0.1-0.20.4-0.4-0.3-0.3-0.6-0.40.30.30.30.3-0.20.5-0.20.9-1.1
Reaction time mean minus median AUC0.20.21.70.3-0.3-0.30.00.2-0.3-0.2-0.5-0.4-0.60.10.10.10.1-0.40.9-0.40.9-1.3
Reaction time num false alarms2.43.25.8-1.92.42.0-2.0-1.8-1.82.01.6-1.51.7-2.0-2.0-2.00.81.81.1-2.01.7-1.2
Reaction time num false alarms AUC1.92.64.6-1.62.11.7-1.8-1.6-1.61.91.6-1.31.5-1.9-1.9-1.90.41.80.7-1.91.5-1.0
Reaction time trials correct on left0.50.81.51.0-0.9-0.90.90.70.8-0.6-0.80.6-1.00.70.70.7-1.2-0.7-1.20.9-1.10.8
Reaction time trials on left0.40.61.30.9-0.8-0.80.80.60.7-0.5-0.70.5-1.00.60.60.6-1.1-0.6-1.10.8-1.00.7
Reaction time mean0.40.62.6-0.6-0.10.6-0.60.2-1.1-0.30.2-1.60.10.20.20.21.00.31.0-0.41.4-1.2
Reaction time mean AUC0.30.41.9-0.5-0.10.5-0.50.0-0.9-0.10.3-1.40.00.10.10.10.80.30.8-0.41.1-1.0
Median of all reaction times0.30.32.0-0.4-0.30.4-0.50.1-0.9-0.30.2-1.40.00.20.20.20.80.30.6-0.21.1-0.7
Reaction time omissions1.52.14.8-1.01.01.1-1.4-1.7-1.51.72.2-1.50.8-1.7-1.7-1.70.41.60.8-2.10.7-1.0
Reaction time false alarm rate2.43.35.2-1.92.32.0-2.0-1.7-1.81.81.7-1.41.8-1.9-1.9-1.91.11.81.5-2.12.1-1.5
Reaction time premature initiation rate0.30.41.80.30.1-0.40.3-0.20.40.3-0.40.8-0.7-0.2-0.2-0.2-0.7-0.4-1.30.7-1.11.1
Reaction time premature initiations0.81.14.20.9-0.5-0.90.90.20.9-0.2-0.81.1-1.30.20.20.2-1.4-0.8-2.01.2-1.71.5
Std. dev. reaction times0.50.72.5-0.80.40.8-0.8-0.1-1.10.10.5-1.50.4-0.1-0.1-0.11.00.61.1-0.91.4-1.6
Reaction time trials completed0.40.61.30.9-0.8-0.80.80.60.7-0.5-0.70.5-1.00.60.60.6-1.1-0.6-1.10.8-1.00.7
Reaction time trials AUC0.30.51.10.8-0.7-0.70.70.50.6-0.4-0.60.4-0.80.50.50.5-1.0-0.5-1.00.6-1.00.6
Run reversals in cocaine runway, females0.30.30.7-0.50.80.5-0.5-0.5-0.50.20.5-0.50.7-0.3-0.3-0.30.20.40.8-0.80.7-0.8
Run reversals in cocaine runway, males0.90.92.3-0.91.10.6-0.8-1.5-0.61.30.8-0.20.3-1.1-1.1-1.10.90.50.6-1.31.0-0.9
Latency to leave start box in cocaine runway0.20.21.0-0.20.40.00.0-0.60.30.5-0.30.60.3-0.4-0.4-0.40.7-0.31.0-0.7-0.3-0.0
Latency to leave start box in cocaine runway, F0.00.00.2-0.10.10.1-0.2-0.10.00.1-0.00.30.4-0.0-0.0-0.00.4-0.10.4-0.30.0-0.0
Latency to leave start box in cocaine runway, M0.30.21.3-0.40.80.20.2-0.70.30.5-0.40.40.3-0.4-0.4-0.40.7-0.21.1-0.4-0.2-0.1
Std. dev. time between licks in bursts0.40.51.40.0-0.1-0.40.41.00.5-0.6-1.20.6-0.20.60.60.61.1-1.10.41.0-1.00.6
Total sessions with >9 infusions0.10.10.90.6-0.7-0.30.20.00.2-0.0-0.20.2-0.10.00.00.0-0.90.1-0.70.20.3-0.2
Short access day 1 total inactive lever presses0.10.20.70.40.4-0.30.5-0.20.60.1-0.50.9-0.4-0.1-0.1-0.1-0.6-0.2-0.0-0.1-0.70.0
Short access day 10 total inactive lever presses1.31.43.2-1.71.51.6-1.3-0.7-1.50.60.8-1.81.1-0.6-0.6-0.61.21.11.2-1.20.9-1.6
Short access day 1 total infusions0.40.51.9-0.30.50.5-0.6-0.7-0.60.70.3-0.50.5-0.7-0.7-0.70.20.60.7-0.61.4-0.9
Short access day 10 total infusions0.30.41.40.3-0.10.0-0.2-0.8-0.20.80.60.2-0.0-0.8-0.8-0.8-1.20.7-0.7-0.40.30.2
Short access total infusions0.10.10.50.5-0.2-0.20.3-0.40.20.4-0.00.5-0.2-0.4-0.4-0.4-0.70.1-0.30.0-0.00.2
Short access day 1 locomotion1.41.53.6-1.20.91.6-1.2-0.5-1.30.61.3-1.61.8-0.6-0.6-0.60.51.71.1-1.11.9-1.4
Short access day 10 total locomotion3.03.35.22.0-2.3-1.92.12.11.9-2.0-1.71.5-1.92.02.02.0-1.5-1.6-1.41.7-1.11.0
Short access total locomotion0.30.30.80.2-0.7-0.20.60.80.4-0.7-0.3-0.0-0.30.70.70.70.0-0.2-0.40.9-0.20.4
One hour access (0.3 mA shock)1.92.24.21.6-1.7-1.81.80.71.8-0.7-1.22.0-1.60.70.70.7-1.4-1.5-1.91.4-1.92.1
Compulsive drug intake0.90.91.80.9-1.4-0.80.81.30.5-1.3-1.00.1-1.11.31.31.3-0.5-0.8-0.81.0-0.00.0
One hour access (shock baseline)0.50.61.80.4-0.3-0.50.5-0.80.70.80.31.2-0.3-0.8-0.8-0.8-0.8-0.1-1.00.0-1.21.3
Social response proportion0.91.02.31.4-0.6-1.20.91.20.9-0.9-1.51.2-1.40.90.90.9-1.0-1.10.30.3-0.0-0.4
Social responses1.92.54.51.5-0.7-1.61.62.11.7-1.9-2.11.8-1.61.81.81.8-1.1-1.8-0.71.5-0.80.4
Social time5.47.210.32.3-2.3-2.83.03.12.9-2.9-2.72.6-2.62.82.82.8-0.9-3.1-2.13.2-3.02.3
Soleus weight4.011.719.1-4.43.94.1-3.7-3.2-3.73.12.9-4.03.5-3.1-3.1-3.14.13.23.5-2.42.8-2.7
Bone: stiffness1.52.47.1-1.11.51.0-1.4-2.7-1.12.51.7-0.50.8-2.4-2.4-2.40.61.20.7-1.50.4-0.2
Tibialis anterior weight1.44.89.7-2.82.32.8-2.4-1.9-2.21.93.1-2.72.4-2.0-2.0-2.01.82.91.0-1.81.3-1.0
Time to tail flick, vehicle, before self-admin0.40.41.70.8-0.3-0.90.8-0.40.80.1-0.91.3-1.2-0.0-0.0-0.0-0.5-0.8-0.0-0.1-0.40.5
Time to tail flick, vehicle, after self-admin0.10.10.60.6-0.8-0.40.10.3-0.0-0.4-0.20.20.00.50.50.5-0.3-0.30.10.20.4-0.2
Time to tail flick, test, before self-admin0.70.72.20.00.80.1-0.4-1.4-0.11.50.60.70.3-1.4-1.4-1.4-0.10.50.7-1.0-0.0-0.2
Time to tail flick, test, after self-admin0.40.51.2-0.10.7-0.2-0.1-1.10.11.00.00.7-0.4-1.1-1.1-1.10.1-0.30.1-1.0-0.70.4
Delta time to tail flick, vehicle, before/after SA0.20.20.8-0.4-0.10.3-0.20.6-0.2-0.40.4-0.50.90.40.40.40.90.00.30.40.00.0
Delta time to tail flick, test, before/after SA0.30.30.60.1-0.3-0.30.40.50.4-0.6-0.50.1-0.60.50.50.50.0-0.7-0.80.5-0.80.5
Tibia length0.00.10.30.1-0.6-0.1-0.1-0.3-0.10.40.2-0.2-0.00.00.00.00.30.00.3-0.30.4-0.3
Ambulatory time before self-admin0.91.02.3-1.01.51.1-0.9-1.0-0.91.10.7-0.71.2-1.0-1.0-1.00.41.00.7-1.21.0-0.9
Ambulatory time after self-admin0.60.73.8-1.51.91.0-0.6-0.3-0.60.30.4-0.51.2-0.3-0.3-0.31.30.30.7-0.8-0.0-0.0
Bone: tissue strength0.30.31.0-0.20.30.5-0.4-0.4-0.40.51.0-0.40.3-0.4-0.4-0.4-0.91.0-1.0-0.20.10.6
Total heroin consumption0.40.51.60.10.3-0.3-0.0-1.30.11.10.30.6-0.5-1.1-1.1-1.1-0.0-0.00.2-0.2-0.91.0
Bone: trabecular number5.17.912.6-3.23.53.0-2.9-3.0-2.73.13.4-2.13.0-3.1-3.1-3.12.73.02.5-2.31.4-1.0
Bone: trabecular spacing1.72.25.12.0-2.2-1.91.60.71.6-0.7-1.61.6-2.10.80.80.8-1.6-1.5-1.51.0-1.50.8
Bone: trabecular thickness0.81.04.3-1.61.51.1-0.8-0.7-0.60.71.0-0.51.2-0.6-0.6-0.62.10.51.5-0.4-0.1-0.2
Bone: trabecular tissue density2.23.15.31.1-1.3-1.61.92.12.0-1.8-1.51.6-1.22.02.02.0-0.2-1.9-1.71.9-2.32.1
Water consumed over 24 hours1.62.04.21.1-0.8-1.31.41.41.4-1.1-1.91.4-1.51.11.11.1-0.7-1.6-1.52.0-1.32.0
Number of responses in last shaping day0.80.83.3-0.50.90.8-0.7-0.4-0.80.40.3-0.70.6-0.4-0.4-0.40.00.91.5-1.21.8-1.8