Hub : Genes

Lekr1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA alternative polyA XM_017590967.2 0.31 0.17 3.1e-03 -0 0.03 0.05 0 6.2e-01 1.6e-02 1.5e-03 2.2e-01
2 Adipose isoform ratio XM_039102619.1 0.03 0.02 1.9e-03 0.02 0.01 0.01 0.01 5.4e-03 1.3e-02 1.1e-02 2.9e-02
3 PL isoform ratio XM_039102619.1 0.07 0.04 4.6e-04 0.04 0.03 0.02 0.03 6.4e-05 2.9e-04 1.1e-03 1.4e-04
4 Brain alternative TSS XM_039102617.1 0.06 0.04 3.9e-03 0.01 0.01 0.01 0.01 2.4e-02 2.5e-02 7.0e-02 2.6e-02
5 Adipose alternative TSS XM_039102620.1 0.04 0.02 5.7e-06 0.01 0.03 0.02 0.01 9.7e-03 5.5e-04 1.7e-03 6.9e-03
6 Brain alternative polyA XM_039102618.1 0.03 0.03 9.6e-03 0 0 -0 -0 2.0e-01 3.3e-01 4.7e-01 4.7e-01
7 Adipose alternative TSS XM_017590967.2 0.04 0.02 3.5e-05 0 0.02 0.02 0.01 9.2e-02 1.8e-03 2.8e-03 8.6e-03
8 pVTA alternative TSS XM_039102617.1 0.06 0.04 3.7e-03 0.05 0.04 0.03 0.04 3.1e-03 6.2e-03 1.4e-02 8.1e-03
9 Brain isoform ratio XM_039102616.1 0.04 0.02 1.2e-03 0.03 0.03 0.03 0.03 4.6e-04 1.9e-03 1.2e-03 1.3e-03
10 IL isoform ratio XM_039102619.1 0.22 0.12 6.1e-04 0.15 0.07 0.07 0.11 1.7e-04 9.5e-03 1.2e-02 1.3e-03
11 Brain isoform ratio XM_039102619.1 0.06 0.04 8.6e-06 0.02 0.03 0.01 0.02 3.2e-03 1.1e-03 2.1e-02 5.2e-03
12 pVTA alternative TSS XM_039102617.1 0.05 0.04 9.6e-03 0.05 0.02 -0 0.02 2.8e-03 3.0e-02 3.4e-01 3.1e-02
13 BLA alternative polyA NM_001115029.2 0.28 0.16 6.3e-03 -0 0.01 0.04 -0 6.7e-01 1.1e-01 5.1e-03 3.7e-01
14 Brain gene expression Lekr1 0.07 0.04 2.4e-04 0 0.03 0.03 0.01 1.6e-01 3.8e-04 1.3e-03 2.1e-02
15 Brain alternative TSS XM_039102620.1 0.06 0.04 1.5e-05 0.03 0.05 0.07 0.06 9.6e-04 2.8e-05 8.4e-07 2.0e-06
16 Brain alternative TSS XM_039102617.1 0.04 0.03 9.4e-03 0.02 0.01 0 0.01 9.1e-03 7.3e-02 1.7e-01 7.3e-02
17 Brain isoform ratio XM_039102617.1 0.07 0.04 8.4e-04 0.02 0.04 0.04 0.03 2.6e-03 2.7e-04 2.4e-04 3.6e-04
18 Brain alternative TSS XM_017590967.2 0.06 0.04 4.2e-05 0.03 0.04 0.06 0.05 1.4e-03 1.2e-04 2.9e-06 1.0e-05
19 Brain isoform ratio NM_001115029.2 0.03 0.02 7.0e-03 0.02 0.01 0 0.01 3.9e-03 5.7e-02 2.7e-01 5.1e-02
20 Adipose gene expression Lekr1 0.26 0.1 0.0e+00 0.12 0.15 0.14 0.14 1.0e-13 6.4e-16 9.6e-16 2.2e-15

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density8.414.123.94.2-4.9-4.14.74.6-4.44.54.44.4-4.44.34.4-2.4-3.5-2.61.92.7-2.01.81.4
Area under the delay curve0.50.52.30.8-0.2-1.50.80.1-0.60.10.50.5-0.50.10.6-1.10.20.6-0.10.90.8-1.11.0
BMI with tail0.41.45.21.00.7-1.5-0.3-1.20.9-1.2-0.7-0.70.6-1.3-0.4-1.40.62.0-1.3-0.22.2-2.30.0
BMI without tail0.30.73.51.2-0.7-1.91.10.5-0.70.40.70.7-0.70.40.8-1.0-0.20.40.00.90.7-0.90.7
Body weight0.52.06.21.30.3-1.9-0.3-0.90.9-0.9-0.9-1.00.9-1.3-0.7-2.0-0.32.3-2.0-0.92.5-2.4-0.9
Weight adjusted by age0.60.73.21.0-0.6-1.80.70.8-1.10.70.90.9-0.90.61.1-0.8-0.80.10.10.40.2-0.30.5
Bone surface3.56.114.03.5-3.6-3.72.83.1-2.63.12.42.3-2.32.42.4-2.7-3.5-0.7-0.20.7-0.20.3-0.4
Bone volume5.59.319.13.8-4.4-3.83.63.9-3.43.93.33.2-3.23.43.2-2.5-3.9-1.70.71.3-1.21.30.0
Breakpoint value in progressive ratio session0.10.10.5-0.30.00.0-0.5-0.20.6-0.1-0.3-0.30.3-0.2-0.40.0-0.30.0-0.3-0.7-0.00.2-0.7
Number of licking bursts1.72.05.42.0-1.8-2.31.31.6-1.51.61.51.5-1.51.31.5-1.7-2.0-0.4-0.20.3-0.10.2-0.1
Context. condit. distance diff. score3.74.58.01.5-2.0-1.62.62.5-2.82.42.72.7-2.72.52.7-0.3-1.2-1.81.82.1-1.51.31.7
Locomotion velocity, session 10.10.10.40.00.20.7-0.1-0.20.2-0.20.10.1-0.1-0.00.2-0.00.4-0.20.30.1-0.30.30.2
Locomotion distance, session 11.11.43.1-0.51.11.0-1.7-1.11.5-1.1-1.5-1.51.5-1.3-1.4-0.20.10.8-1.3-1.60.6-0.3-1.4
Locomotion velocity, session 20.30.41.30.3-0.80.10.20.8-0.30.90.40.4-0.40.80.4-0.2-1.0-0.90.3-0.2-1.01.2-0.5
Locomotion distance, session 22.23.16.1-1.01.41.3-2.5-1.62.2-1.5-2.3-2.32.3-1.9-2.30.00.11.4-1.9-2.31.1-0.7-2.1
Locomotion velocity, session 30.60.72.31.5-0.9-1.50.40.7-0.20.70.50.5-0.50.30.6-1.5-1.40.5-0.8-0.50.6-0.5-0.6
Locomotion distance, session 31.71.94.72.2-1.9-1.81.61.5-1.21.51.51.5-1.51.41.6-1.5-1.4-0.80.40.7-0.50.50.2
Stereotopy head waving bouts, day 30.70.82.81.7-1.1-1.10.90.9-0.70.91.11.1-1.10.81.0-1.4-1.0-0.2-0.10.3-0.10.10.1
Stereotopy head waving duration, day 30.70.92.01.4-1.0-0.90.81.1-0.91.11.31.2-1.20.91.1-1.2-1.2-0.3-0.00.2-0.10.20.1
Locomotion velocity, session 70.30.31.4-1.20.80.8-0.5-0.40.5-0.4-0.5-0.50.5-0.4-0.41.10.60.10.1-0.20.1-0.00.1
Locomotion distance, session 70.70.82.4-1.10.41.20.4-0.0-0.2-0.10.40.4-0.40.40.41.61.3-1.11.51.2-1.21.01.3
Stereotopy head waving bouts, day 70.10.20.70.6-0.6-0.1-0.00.40.20.4-0.00.0-0.00.20.1-0.6-0.9-0.1-0.4-0.6-0.10.3-0.7
Stereotopy head waving duration, day 70.70.82.50.6-0.1-0.5-0.8-0.20.7-0.1-0.8-0.80.8-0.6-0.6-1.1-1.21.0-1.6-1.51.0-0.7-1.6
Locomotion velocity, session 80.20.30.80.20.7-0.1-0.6-0.50.3-0.5-0.1-0.10.1-0.6-0.1-0.60.10.9-0.7-0.50.9-0.9-0.1
Locomotion distance, session 80.10.20.4-0.60.40.5-0.6-0.10.2-0.1-0.5-0.50.5-0.2-0.40.4-0.2-0.0-0.2-0.6-0.10.3-0.5
Degree of sensitization distance2.52.68.2-2.92.32.7-1.3-1.71.0-1.7-1.1-1.11.1-1.2-1.22.62.6-0.00.80.5-0.30.01.0
Degree of sensitization stereotypy0.20.20.7-0.1-0.10.4-0.5-0.10.5-0.0-0.6-0.50.5-0.2-0.4-0.1-0.40.0-0.4-0.8-0.00.2-0.8
Conditioned locomotion0.40.41.20.9-0.6-1.0-0.10.00.60.1-0.2-0.20.2-0.2-0.3-1.0-1.00.6-1.0-0.90.6-0.4-1.1
Cocaine response after cond. corrected0.80.94.3-1.01.51.2-0.2-1.20.4-1.3-0.0-0.00.0-0.8-0.11.02.10.60.50.80.5-0.91.4
Cocaine response after cond. not corrected1.01.03.2-1.01.71.0-0.7-1.40.8-1.5-0.5-0.50.5-1.2-0.60.71.81.1-0.10.21.1-1.30.8
Cocaine response before conditioning0.30.31.50.6-0.7-1.10.20.7-0.50.70.10.1-0.10.30.3-0.8-1.20.3-0.6-0.40.4-0.3-0.5
Saline control response1.21.65.31.8-0.7-2.20.20.3-0.10.30.20.2-0.2-0.30.0-2.3-1.61.6-1.7-0.91.9-1.7-1.0
Bone: connectivity density5.18.113.63.5-3.6-3.63.73.2-3.33.23.43.4-3.43.03.4-2.1-2.4-1.51.22.3-1.00.71.5
Bone: cortical apparent density2.02.67.1-0.4-0.50.91.60.8-1.30.71.71.6-1.61.41.61.41.3-2.12.72.4-2.01.62.4
Bone: cortical area1.92.910.52.4-2.6-3.11.42.1-1.52.11.01.0-1.01.20.9-2.1-3.20.2-1.1-0.50.6-0.3-1.3
Bone: cortical porosity2.22.45.1-1.41.10.9-1.9-1.31.7-1.2-2.3-2.22.2-1.6-2.10.60.01.2-1.5-1.81.0-0.7-1.8
Bone: cortical porosity1.51.64.0-0.80.50.2-1.4-0.71.3-0.6-1.9-1.91.9-1.1-1.70.1-0.71.0-1.6-1.90.8-0.5-2.0
Bone: cortical thickness1.22.06.01.7-2.3-2.11.41.9-1.52.01.21.2-1.21.41.0-1.3-2.5-0.6-0.2-0.0-0.30.5-0.7
Bone: cortical thickness2.63.09.23.0-2.3-2.61.61.8-1.51.81.81.7-1.71.51.9-2.6-2.2-0.3-0.50.30.00.0-0.2
Bone: cortical tissue density2.12.77.5-0.4-0.40.91.60.7-1.30.61.71.7-1.71.41.61.41.4-2.12.72.5-2.01.62.5
Condit. Reinf. active minus inactive responses4.14.68.3-0.51.90.5-2.5-2.52.9-2.4-2.4-2.42.4-2.7-2.4-0.80.82.5-2.4-2.32.3-2.0-1.8
Condit. Reinf. active-inactive response ratio3.74.07.8-0.51.70.7-2.5-2.32.8-2.2-2.3-2.32.3-2.5-2.4-0.70.62.1-2.2-2.31.9-1.5-2.0
Condit. Reinf. active responses6.17.412.0-0.82.40.6-3.0-3.03.5-3.0-3.1-3.13.1-3.3-3.1-0.80.93.3-3.1-2.83.1-2.8-2.2
Condit. Reinf. inactive responses1.61.94.1-0.71.50.3-1.2-1.71.5-1.7-1.3-1.41.4-1.7-1.30.01.22.0-1.3-0.72.0-2.0-0.2
Incentive salience index mean3.44.16.8-1.21.91.1-2.4-2.32.6-2.2-2.5-2.52.5-2.4-2.50.10.92.0-1.9-2.11.8-1.5-1.7
Condit. Reinf. lever presses1.52.13.8-2.01.61.9-1.7-1.51.5-1.4-1.9-1.91.9-1.4-1.81.41.10.7-0.6-1.10.4-0.3-0.8
Condit. Reinf. active minus inactive responses0.60.72.00.70.2-0.8-0.5-0.60.6-0.6-0.4-0.40.4-0.8-0.5-1.3-0.31.3-1.3-0.81.4-1.3-0.7
Condit. Reinf. active-inactive response ratio0.40.41.40.50.6-0.3-0.2-0.90.5-0.9-0.0-0.00.0-0.7-0.0-0.80.91.0-0.40.21.0-1.20.4
Condit. Reinf. active responses0.60.82.40.5-0.3-0.8-0.6-0.10.5-0.1-0.8-0.80.8-0.6-0.8-1.1-1.10.9-1.5-1.31.0-0.7-1.5
Condit. Reinf. inactive responses0.40.42.20.1-0.7-0.3-0.20.6-0.10.6-0.6-0.60.60.1-0.6-0.2-1.5-0.0-0.7-1.0-0.10.4-1.4
Condit. Reinf. lever presses2.12.94.5-0.61.60.5-1.9-2.02.1-1.9-1.9-1.91.9-2.1-1.9-0.50.72.0-1.9-1.81.9-1.7-1.4
Condit. Reinf. lever reinforcers received0.60.82.70.6-0.3-0.7-0.7-0.20.7-0.1-0.8-0.80.8-0.6-0.8-1.2-1.10.8-1.5-1.40.8-0.5-1.6
Conditioned reinforcement - actives0.90.95.2-1.80.82.3-0.7-0.30.1-0.3-0.7-0.60.6-0.2-0.62.30.8-0.20.6-0.1-0.40.40.1
Conditioned reinforcement - inactives1.92.23.5-1.31.60.9-1.7-1.71.8-1.7-1.8-1.81.8-1.8-1.90.41.01.4-1.2-1.31.3-1.1-0.9
Conditioned locomotion0.30.32.2-1.00.51.2-0.70.1-0.30.1-0.4-0.40.3-0.0-0.41.5-0.1-0.10.1-0.4-0.30.4-0.2
Patch foraging indifference point 0 sec0.40.62.01.1-1.2-1.20.61.0-0.81.00.70.7-0.70.60.5-1.1-1.40.1-0.2-0.20.3-0.1-0.4
Patch foraging indifference point AUC0.50.61.9-1.41.01.2-0.9-0.70.5-0.7-0.7-0.70.7-0.6-0.81.30.80.5-0.1-0.30.3-0.40.0
Delay disc. indifference point, 0s delay1.11.26.52.5-1.4-0.91.00.40.40.50.70.7-0.70.60.9-2.6-0.7-0.90.30.0-0.80.9-0.6
Delay disc. indifference point, 16s delay0.70.73.10.20.4-0.50.8-0.5-0.1-0.60.60.6-0.6-0.10.7-0.41.50.40.71.60.6-1.11.8
Delay disc. indifference point, 2s delay0.60.72.81.4-0.9-1.70.50.6-0.30.6-0.0-0.00.00.20.1-1.7-1.30.4-0.9-0.40.6-0.4-0.7
Delay disc. indifference point, 24s delay0.60.62.6-0.80.4-0.80.80.0-1.0-0.10.50.5-0.50.10.40.50.80.50.31.30.7-1.21.6
Delay disc. indifference point, 4s delay0.70.83.61.0-1.0-1.91.01.1-1.21.00.60.6-0.60.80.7-1.0-1.10.1-0.20.40.3-0.30.2
Delay disc. indifference point, 8s delay0.20.20.70.6-0.0-0.80.4-0.0-0.2-0.00.20.2-0.2-0.00.3-0.80.20.4-0.10.40.6-0.70.5
Indifference point function ln k0.10.20.90.9-0.6-0.60.20.10.10.10.10.1-0.10.10.1-1.0-0.5-0.2-0.1-0.2-0.20.3-0.4
Indifference point function log k0.10.20.90.9-0.6-0.60.20.10.10.10.10.1-0.10.10.1-1.0-0.5-0.2-0.1-0.2-0.20.3-0.4
Patch foraging total patch changes 0 sec0.30.41.30.9-1.0-0.90.40.7-0.60.70.60.6-0.50.50.4-1.0-1.10.2-0.2-0.20.3-0.2-0.4
Patch foraging total patch changes 12 sec0.30.41.00.3-0.5-0.10.50.8-1.00.70.80.8-0.80.80.70.0-0.3-0.50.60.6-0.40.30.6
Patch foraging total patch changes 18 sec0.40.51.70.7-0.7-0.90.51.0-1.31.00.80.8-0.80.70.7-0.6-0.90.1-0.00.30.3-0.30.3
Patch foraging total patch changes 24 sec0.20.21.11.0-0.5-0.40.20.4-0.40.40.60.6-0.50.40.4-0.9-0.6-0.1-0.0-0.0-0.00.0-0.1
Patch foraging total patch changes 6 sec0.10.10.80.7-0.4-0.3-0.10.10.00.2-0.0-0.00.00.0-0.0-0.9-0.50.2-0.3-0.50.2-0.1-0.5
Patch foraging time to switch 0 sec1.01.53.00.4-0.6-0.71.51.0-1.61.01.61.6-1.61.21.70.30.1-1.11.41.7-1.00.61.7
Patch foraging water rate 0 sec1.21.93.6-1.11.21.0-1.7-1.31.5-1.3-1.7-1.71.7-1.5-1.90.30.31.5-1.3-1.61.4-1.1-1.4
Patch foraging water rate 12 sec0.40.62.01.4-1.1-0.60.80.9-0.40.90.80.8-0.80.90.8-1.0-0.9-0.80.40.1-0.70.8-0.2
Patch foraging water rate 18 sec1.11.53.50.10.90.9-1.5-1.21.9-1.2-1.5-1.51.5-1.4-1.6-0.60.10.8-1.3-1.70.6-0.3-1.7
Patch foraging water rate 24 sec0.30.41.91.3-0.7-0.30.10.20.70.2-0.1-0.10.10.1-0.1-1.4-0.8-0.4-0.3-0.8-0.40.7-1.0
Patch foraging water rate 6 sec0.91.37.32.4-1.2-1.50.10.40.70.40.00.0-0.00.0-0.0-2.7-1.70.2-1.2-1.20.20.2-1.7
Seeking ratio, delayed vs. immediate footshock1.51.73.20.7-1.0-0.61.61.3-1.81.21.81.8-1.81.51.70.2-0.2-1.11.31.7-0.90.61.5
Distance traveled before self-admin0.20.20.50.3-0.3-0.30.40.20.10.20.60.6-0.60.40.6-0.10.1-0.60.70.4-0.60.60.3
Distance traveled after self-admin0.91.03.11.1-0.90.41.10.00.90.00.80.8-0.80.60.7-0.90.7-1.71.40.8-1.81.70.3
Extensor digitorum longus weight2.610.316.9-0.72.20.0-3.4-3.23.5-3.1-4.0-4.04.0-3.8-3.9-1.20.43.9-4.1-3.53.7-3.3-3.2
Bone: elastic displacement0.30.31.31.1-0.9-0.90.40.6-0.20.60.20.2-0.20.40.3-1.1-1.0-0.1-0.3-0.3-0.10.2-0.6
Bone: elastic work1.41.97.12.3-2.0-2.00.41.3-0.11.40.30.4-0.40.80.4-2.3-2.7-0.1-1.1-1.2-0.00.5-1.9
Bone: endosteal estimation0.51.03.71.3-0.9-1.90.40.6-0.20.6-0.0-0.00.00.00.1-1.5-1.71.1-1.4-0.81.3-1.1-1.1
Bone: endosteal perimeter0.81.66.21.9-1.7-2.51.11.4-1.11.50.60.6-0.60.80.7-1.7-2.40.4-1.0-0.40.7-0.5-0.9
Epididymis fat weight1.22.75.61.4-1.2-1.62.21.6-2.41.52.22.1-2.11.72.2-0.6-0.4-0.91.42.0-0.60.32.0
Delta time in closed arm before/after self-admin0.10.00.3-0.20.10.6-0.3-0.00.20.00.00.0-0.00.00.10.2-0.0-0.20.3-0.2-0.30.4-0.1
Delta time in open arm before/after self-admin0.20.21.2-0.3-0.6-0.40.00.7-0.50.70.10.1-0.10.4-0.00.2-1.1-0.2-0.3-0.5-0.20.4-0.7
Diff in mean of infusions in LGA sessions1.92.15.0-0.31.10.2-2.1-1.42.1-1.3-1.6-1.61.6-1.6-1.4-0.7-0.21.4-1.6-2.21.1-0.7-1.9
Delay discount exponential model param0.40.42.1-0.40.11.4-0.7-0.10.7-0.1-0.3-0.30.3-0.0-0.40.7-0.1-0.70.2-0.8-0.91.2-0.8
Extinction: sum of active levers before priming3.83.87.2-0.61.80.7-2.4-2.22.7-2.1-2.3-2.32.3-2.3-2.3-0.80.82.1-2.2-2.11.9-1.6-1.7
Active lever presses in extinction session 60.30.32.21.10.0-1.10.0-0.40.8-0.40.30.3-0.3-0.30.2-1.50.20.4-0.2-0.00.5-0.50.0
Bone: final force2.33.713.53.0-2.8-3.41.42.1-1.32.21.00.9-0.91.20.9-2.8-3.70.3-1.6-0.90.6-0.2-1.8
Bone: final moment2.54.114.93.1-3.1-3.41.52.3-1.32.31.01.0-1.01.40.9-2.9-3.90.1-1.4-0.90.4-0.0-1.9
Food consumed during 24 hour testing period0.10.20.6-0.20.2-0.10.5-0.2-0.2-0.30.10.1-0.1-0.10.10.40.70.30.20.80.4-0.60.7
Glucose0.40.61.51.0-0.0-1.10.70.0-0.6-0.00.90.8-0.90.10.8-1.00.30.8-0.10.81.0-1.21.1
Heart weight0.10.10.6-0.40.2-0.40.10.3-0.80.30.00.1-0.10.10.00.6-0.20.10.10.20.2-0.30.3
Delay discount hyperbolic model param0.40.42.1-0.50.11.5-0.5-0.10.6-0.0-0.1-0.10.10.0-0.20.90.0-0.80.4-0.5-1.01.2-0.6
Intermittent access intake day 1-15 change0.20.20.9-1.00.30.3-0.3-0.1-0.2-0.1-0.5-0.50.6-0.2-0.61.00.00.5-0.2-0.20.5-0.5-0.1
Intermittent access intake escalation0.30.31.7-1.20.30.6-0.2-0.0-0.3-0.0-0.5-0.50.6-0.1-0.61.30.20.3-0.0-0.10.3-0.30.0
Intermittent access intake escalation 20.20.20.50.3-0.6-0.20.70.4-0.20.40.30.4-0.20.50.30.30.0-0.50.60.5-0.40.30.3
Intermitt. access day 1 inactive lever presses1.81.92.9-1.51.70.3-1.6-1.51.3-1.5-1.4-1.51.6-1.6-1.70.50.81.7-1.4-1.11.6-1.5-0.6
Intermitt. access day 15 inactive lever presses2.12.34.4-1.41.21.7-1.8-1.62.1-1.5-1.9-1.92.0-1.6-2.00.50.61.0-1.2-1.80.8-0.5-1.6
Intermitt. access escalation Index0.70.62.2-0.40.11.1-1.0-0.31.1-0.3-1.0-0.90.9-0.5-0.8-0.2-0.5-0.1-0.5-1.4-0.30.7-1.5
Intermittent access day 1 total infusions1.61.96.6-2.61.92.3-1.4-1.30.8-1.3-1.3-1.31.2-1.2-1.22.01.40.9-0.4-0.40.7-0.80.2
Intermittent access day 15 total infusions2.12.38.5-2.91.72.7-1.5-1.31.0-1.3-1.7-1.61.6-1.2-1.62.41.30.8-0.3-0.70.6-0.6-0.2
Intermittent access terminal intake (last 3 days)2.02.27.2-2.71.52.5-1.5-1.21.2-1.2-1.7-1.71.7-1.2-1.72.31.10.8-0.5-1.00.6-0.5-0.5
Intermittent access total infusions2.32.510.5-3.21.63.0-1.6-1.21.0-1.2-1.7-1.71.6-1.2-1.62.71.20.6-0.3-0.90.4-0.3-0.4
Intermittent access day 1 locomotion1.51.55.9-2.41.72.3-1.4-1.10.7-1.1-1.1-1.11.0-1.0-1.02.01.40.4-0.1-0.40.2-0.20.2
Intermittent access day 15 total locomotion0.40.42.0-1.40.71.0-0.5-0.70.7-0.7-0.6-0.60.5-0.6-0.51.00.90.30.0-0.10.2-0.20.1
Intermittent access total locomotion0.91.05.0-2.21.21.8-1.0-0.80.5-0.8-1.0-0.90.9-0.7-0.82.00.90.4-0.0-0.30.2-0.20.0
Intermittent access standard deviation1.01.13.70.1-0.5-0.01.40.6-1.10.61.21.2-1.01.01.10.60.8-0.91.51.9-0.80.41.7
Left kidney weight0.41.23.70.1-1.6-0.71.01.8-1.21.80.60.6-0.51.40.60.6-1.9-1.10.6-0.1-1.01.2-0.7
Right kidney weight0.30.71.9-0.3-1.1-0.10.51.3-0.91.30.20.2-0.21.00.20.9-1.4-1.00.5-0.2-1.01.3-0.7
Cocaine induced anxiety0.81.01.81.2-1.00.21.00.9-0.40.91.21.2-1.21.11.2-0.6-0.3-1.31.10.7-1.31.30.4
Post-drug Anxiety0.10.10.60.50.10.7-0.2-0.50.8-0.5-0.1-0.10.1-0.3-0.1-0.40.5-0.20.2-0.1-0.20.3-0.1
Baseline Anxiety3.33.55.6-1.92.10.4-2.2-1.71.2-1.7-2.3-2.32.3-2.1-2.31.00.62.4-2.1-1.62.2-2.1-1.1
Tail length0.20.72.60.7-1.4-1.60.81.2-1.01.30.50.4-0.50.80.4-0.7-1.6-0.1-0.3-0.10.10.0-0.5
Length with tail0.31.23.90.6-0.6-1.2-0.60.20.30.2-0.9-1.01.0-0.4-1.0-1.2-1.71.1-1.8-1.71.1-0.7-2.0
Length without tail0.71.53.70.30.40.0-1.3-0.91.4-0.8-1.4-1.41.4-1.2-1.4-1.0-0.61.1-1.7-1.91.0-0.6-1.9
Times rat made contact with spout2.42.86.00.8-1.6-1.32.31.9-2.51.82.02.0-2.01.92.10.3-0.7-1.21.52.1-0.90.61.7
Lifetime Intake1.82.08.7-3.01.52.8-1.5-1.00.9-1.0-1.4-1.41.4-1.0-1.42.41.00.4-0.2-0.80.2-0.1-0.4
Liver weight, left0.10.10.40.0-0.1-0.60.40.2-0.50.10.20.2-0.20.10.30.1-0.10.4-0.20.30.5-0.60.3
Liver weight, right0.30.51.80.1-0.4-1.30.20.4-0.50.4-0.4-0.40.4-0.1-0.2-0.2-1.21.0-1.1-0.61.2-1.0-0.7
Locomotor activity0.81.35.31.10.40.3-1.2-1.42.3-1.3-1.0-1.01.0-1.3-1.1-1.90.40.7-0.9-1.30.6-0.3-1.4
Locomotor testing distance1.72.98.41.11.20.4-1.7-2.32.9-2.3-1.4-1.41.4-2.2-1.6-2.41.21.5-1.4-1.41.4-1.3-1.3
Locomotor testing rearing0.61.06.82.3-0.7-0.6-0.4-0.41.4-0.4-0.2-0.20.2-0.4-0.3-2.6-0.60.1-0.7-1.00.00.2-1.4
Locomotion in novel chamber1.31.68.1-2.1-0.31.90.40.5-0.30.60.20.2-0.20.80.32.80.4-1.81.60.6-1.91.90.4
Locomotion in novel chamber post-restriction0.20.31.2-0.2-0.41.00.10.40.10.50.20.3-0.30.6-0.00.3-0.1-0.90.60.0-1.01.1-0.2
Fecal boli incidents, locomotor time 11.11.24.4-0.61.60.9-0.7-1.71.3-1.8-0.7-0.70.7-1.3-0.70.22.11.0-0.20.41.0-1.30.9
Change in fecal boli incidents, locomotor task3.53.35.40.4-1.8-0.92.32.0-2.32.02.12.1-2.12.22.10.6-0.6-2.02.02.2-1.81.51.5
Time >=10cm from walls, locomotor time 10.80.81.40.4-0.9-0.11.21.0-0.61.01.11.1-1.11.11.1-0.1-0.3-1.11.00.9-1.11.00.6
Bouts of movement, locomotor time 10.30.41.10.0-0.6-0.10.30.9-1.01.00.10.1-0.10.70.10.4-1.1-0.8-0.0-0.1-0.80.9-0.4
Total resting periods, locomotor time 10.80.92.20.4-1.1-0.20.71.4-1.21.40.60.6-0.61.20.70.2-1.2-1.40.60.3-1.41.5-0.1
Rest time, locomotor task time 10.91.01.90.9-1.3-0.10.91.3-1.01.31.01.0-1.01.40.9-0.0-0.8-1.30.80.6-1.21.20.3
Distance moved, locomotor task time 11.41.63.6-1.01.6-0.0-1.0-1.50.9-1.6-1.3-1.31.3-1.6-1.10.31.11.8-1.1-0.51.8-1.9-0.0
Vertical activity count, locomotor time 11.31.43.7-1.91.61.1-1.1-1.10.7-1.1-1.5-1.51.5-1.2-1.41.61.00.9-0.5-0.50.7-0.8-0.2
Time >=10cm from walls, locomotor time 20.60.72.8-0.5-0.71.10.10.8-0.20.90.30.3-0.30.90.30.8-0.7-1.31.0-0.2-1.41.7-0.6
Bouts of movement, locomotor time 20.50.51.5-0.7-0.70.60.51.0-0.91.00.00.0-0.00.9-0.11.2-0.7-1.00.3-0.1-1.01.2-0.3
Total resting periods, locomotor time 20.50.51.3-0.6-0.70.30.61.1-1.11.10.10.1-0.10.9-0.01.1-0.8-0.90.20.1-0.91.0-0.2
Rest time, locomotor task time 21.82.03.81.5-2.0-1.31.61.8-1.71.81.41.4-1.41.71.2-0.8-1.5-1.60.60.9-1.41.40.1
Distance moved, locomotor task time 21.11.32.5-1.01.50.6-1.3-1.31.1-1.3-1.1-1.11.1-1.4-1.00.40.81.6-0.9-0.91.5-1.4-0.3
Vertical activity count, locomotor time 20.40.42.1-1.50.90.9-0.6-0.3-0.0-0.3-0.6-0.60.6-0.4-0.51.40.40.6-0.2-0.30.5-0.50.1
Light reinforcement 10.91.74.40.21.4-0.5-1.1-1.61.2-1.7-0.9-0.91.0-1.7-1.0-1.10.92.0-1.6-0.72.0-2.1-0.2
Light reinforcement 21.11.43.3-1.81.71.5-1.2-1.41.0-1.4-1.2-1.21.3-1.3-1.31.31.60.8-0.3-0.20.6-0.70.2
Bone: marrow area0.41.03.61.4-1.0-1.90.50.6-0.30.60.00.0-0.00.10.1-1.5-1.70.9-1.3-0.71.1-0.9-1.1
Bone: maximum diameter2.24.09.02.3-2.7-3.02.42.6-2.52.62.12.0-2.02.12.0-1.6-2.7-0.60.20.8-0.10.20.1
Bone: maximum force1.52.510.12.3-2.1-2.80.61.4-0.71.50.20.2-0.20.60.2-2.4-3.20.8-1.9-1.31.1-0.6-2.1
Bone: maximum moment1.52.510.42.3-2.2-2.70.71.5-0.71.60.20.2-0.20.70.2-2.3-3.20.7-1.7-1.30.9-0.5-2.1
Mean time between licks in bursts4.26.08.8-2.02.91.7-2.8-3.02.8-2.9-2.9-2.92.9-3.0-2.80.61.82.5-2.1-1.92.2-2.1-1.2
Mean num. licks in bursts0.50.62.8-1.40.81.3-0.0-0.60.2-0.6-0.4-0.40.4-0.3-0.41.71.4-0.20.80.6-0.30.10.8
Cd content in liver0.10.21.0-0.20.41.0-0.4-0.30.4-0.3-0.3-0.30.3-0.2-0.50.30.4-0.30.2-0.2-0.40.5-0.1
Co content in liver1.51.73.1-0.61.51.1-1.5-1.81.7-1.8-1.4-1.41.4-1.7-1.3-0.11.31.4-1.0-0.91.3-1.2-0.5
Cu content in liver0.30.31.2-0.10.5-0.0-0.3-0.60.3-0.6-0.5-0.50.5-0.7-0.6-0.10.31.0-0.7-0.21.1-1.1-0.1
Fe content in liver1.51.84.10.8-1.2-1.32.01.4-1.91.31.61.6-1.61.41.7-0.1-0.4-0.71.11.8-0.40.11.5
K content in liver0.70.72.3-0.40.00.3-0.9-0.30.8-0.2-1.1-1.11.1-0.6-1.1-0.1-0.70.6-1.0-1.30.5-0.2-1.5
Mg content in liver1.61.62.8-1.11.10.6-1.5-1.21.3-1.1-1.7-1.71.7-1.4-1.60.30.21.4-1.3-1.41.3-1.2-1.2
Mn content in liver0.30.32.00.40.0-0.70.3-0.1-0.5-0.10.20.2-0.2-0.20.3-0.5-0.01.1-0.40.31.3-1.40.4
Na content in liver0.40.41.20.8-1.1-0.80.60.8-0.40.90.40.4-0.40.70.5-0.7-1.1-0.6-0.0-0.1-0.50.7-0.5
Rb content in liver0.30.41.3-0.30.70.2-0.0-0.90.4-0.9-0.5-0.50.5-0.7-0.50.21.20.8-0.10.40.9-1.10.5
Se content in liver1.01.24.1-0.10.00.51.20.5-1.30.41.21.2-1.20.81.30.71.0-0.71.71.9-0.60.22.0
Sr content in liver0.80.71.40.2-0.9-0.10.71.0-0.71.01.01.0-1.01.11.00.2-0.5-1.21.00.6-1.11.20.3
Zn content in liver0.30.41.6-1.20.70.6-0.0-0.4-0.2-0.5-0.1-0.10.1-0.2-0.11.31.00.40.50.60.4-0.60.8
Bone: minimum diameter1.22.26.91.9-1.3-2.60.20.7-0.10.8-0.3-0.30.3-0.1-0.2-2.2-2.61.5-2.2-1.61.7-1.3-2.0
Time in familiar zone, hab. session 12.32.23.30.5-1.3-0.41.71.7-1.81.61.71.7-1.71.81.70.4-0.6-1.71.71.6-1.51.41.2
Time in novel zone, hab. session 10.40.41.30.30.2-0.5-0.5-0.40.5-0.4-0.4-0.40.4-0.6-0.5-0.8-0.31.1-1.1-0.71.1-1.0-0.6
Total zone transitions, hab. session 11.72.43.7-0.31.60.4-1.9-1.81.8-1.8-1.7-1.71.7-1.9-1.5-0.60.71.9-1.8-1.51.8-1.7-1.0
Total locomotion distance, hab. session 11.72.44.1-0.81.91.4-2.0-2.02.0-2.0-1.7-1.71.7-1.9-1.6-0.01.31.4-1.2-1.31.2-1.1-0.8
Locomotion velocity, hab. session 12.94.17.2-1.42.52.0-2.7-2.52.7-2.5-2.4-2.42.4-2.4-2.30.41.71.6-1.4-1.71.2-1.1-1.1
Time in familiar zone, hab. session 27.57.711.81.7-2.9-1.33.23.2-3.13.23.43.4-3.43.43.3-0.1-1.6-3.12.82.5-2.92.71.7
Time in novel zone, hab. session 24.54.56.9-0.31.80.3-2.4-2.32.5-2.3-2.4-2.42.4-2.6-2.4-1.10.52.6-2.6-2.32.4-2.1-1.8
Total zone transitions, hab. session 21.21.63.5-0.81.31.3-1.9-1.21.5-1.2-1.6-1.61.6-1.3-1.40.10.31.0-1.3-1.60.7-0.5-1.3
Total locomotion distance, hab. session 21.92.54.4-1.42.11.5-2.0-2.01.7-2.0-1.7-1.71.7-1.9-1.70.61.41.6-1.1-1.11.4-1.4-0.5
Locomotion velocity, hab. session 22.33.05.3-1.82.31.9-2.2-2.11.8-2.1-1.9-1.91.9-2.0-2.00.91.61.6-1.2-1.21.3-1.3-0.6
Novel to familiar place preference ratio1.21.23.7-0.60.30.6-1.4-0.51.1-0.5-1.6-1.61.6-0.9-1.5-0.0-0.70.5-1.4-1.80.30.0-1.9
Novelty place preference1.11.24.5-0.40.10.6-1.3-0.31.1-0.2-1.5-1.51.5-0.7-1.4-0.2-1.00.2-1.3-1.9-0.00.5-2.1
Time in novel zone, NPP test1.01.14.8-0.0-0.20.3-1.2-0.11.0-0.0-1.3-1.31.3-0.5-1.2-0.5-1.20.1-1.3-1.9-0.10.5-2.2
Total zone transitions, NPP test2.63.77.7-1.62.01.9-2.8-2.02.5-1.9-2.5-2.52.5-2.1-2.30.60.71.3-1.6-2.31.0-0.6-1.8
Total locomotion distance, NPP test2.63.67.3-1.81.92.2-2.7-1.82.4-1.7-2.4-2.42.4-1.9-2.40.80.71.0-1.4-2.30.7-0.3-1.9
Locomotion velocity, NPP test3.04.28.4-2.22.22.6-2.9-2.12.6-2.0-2.6-2.62.6-2.1-2.61.11.01.1-1.3-2.30.6-0.3-1.8
Intraocular pressure0.30.31.00.40.80.9-0.9-0.81.0-0.8-0.1-0.10.1-0.7-0.2-1.00.60.1-0.4-0.5-0.00.1-0.2
Delta distance traveled before/after self-admin0.80.92.71.6-1.30.40.90.20.80.30.50.5-0.50.60.5-1.50.0-1.50.90.3-1.51.7-0.4
Delta ambulatory time before/after self-admin1.61.74.51.8-1.70.41.60.70.20.71.21.2-1.21.21.1-1.20.1-2.11.51.1-2.12.10.3
Parametrial fat weight0.30.61.81.4-0.8-0.81.10.3-0.10.30.80.9-0.90.51.0-1.10.1-0.30.51.0-0.2-0.00.7
Pavlov. Cond. lever latency0.70.91.61.1-0.7-0.91.30.6-0.80.61.21.2-1.20.81.3-0.60.1-0.71.01.2-0.60.41.0
Pavlov. Cond. magazine entry latency0.20.20.90.4-0.6-0.4-0.10.30.20.4-0.1-0.20.20.1-0.2-0.5-0.9-0.1-0.5-0.7-0.10.3-0.9
Pavlov. Cond. change in total contacts0.91.03.1-1.81.21.6-0.7-1.00.7-1.1-0.8-0.90.9-0.8-1.01.61.50.20.30.10.1-0.20.5
Pavlov. Cond. index score0.10.20.5-0.5-0.20.3-0.30.3-0.00.4-0.3-0.40.40.1-0.40.4-0.7-0.3-0.3-0.6-0.40.5-0.7
Pavlov. Cond. latency score0.10.20.4-0.6-0.10.4-0.40.20.00.3-0.3-0.40.40.0-0.50.5-0.5-0.2-0.2-0.5-0.30.4-0.6
Pavlov. Cond. lever contacts0.80.91.8-1.10.71.0-1.3-0.61.0-0.6-1.3-1.31.3-0.8-1.30.7-0.10.5-0.9-1.30.3-0.1-1.2
Pavlov. Cond. magazine entry number0.50.73.4-0.81.31.1-0.1-0.90.1-0.90.10.2-0.2-0.40.20.81.80.20.80.90.2-0.51.5
Pavlov. Cond. intertrial magazine entries4.04.88.6-2.12.72.3-2.7-2.82.9-2.8-2.7-2.62.6-2.6-2.60.92.11.4-1.0-1.71.1-0.9-0.9
Pavlov. Cond. lever-magazine prob. diff.0.10.10.4-0.5-0.20.2-0.20.4-0.10.4-0.3-0.30.30.2-0.40.5-0.6-0.3-0.2-0.5-0.30.5-0.6
Pavlov. Cond. response bias0.40.52.5-0.1-0.4-0.1-0.70.10.60.2-0.8-0.90.9-0.2-0.9-0.1-1.10.1-1.0-1.3-0.00.4-1.6
Pavlov. Cond. lever latency1.01.42.20.5-1.2-0.61.31.4-1.51.41.31.3-1.31.51.30.2-0.7-1.41.21.1-1.31.20.8
Pavlov. Cond. magazine entry latency1.31.54.62.2-1.9-1.60.71.3-0.41.40.70.7-0.71.00.7-1.9-2.1-0.7-0.4-0.6-0.60.9-1.2
Pavlov. Cond. change in total contacts0.60.81.50.30.6-0.2-0.8-0.91.0-0.9-0.8-0.80.8-1.0-0.8-0.90.01.2-1.2-1.01.2-1.1-0.8
Pavlov. Cond. index score0.50.72.00.9-0.2-0.5-0.6-0.41.0-0.3-0.6-0.60.6-0.6-0.6-1.4-0.80.7-1.3-1.30.7-0.4-1.4
Pavlov. Cond. latency score0.60.72.41.1-0.2-0.6-0.6-0.41.0-0.3-0.5-0.50.5-0.6-0.6-1.5-0.80.7-1.3-1.20.7-0.4-1.4
Pavlov. Cond. lever contacts0.60.91.4-0.61.10.7-1.0-1.21.2-1.2-1.0-1.01.0-1.2-1.00.10.71.0-0.8-0.80.9-0.9-0.5
Pavlov. Cond. magazine entry number0.60.83.5-1.91.31.2-0.4-0.6-0.1-0.7-0.4-0.40.4-0.4-0.41.81.40.30.50.60.2-0.51.1
Pavlov. Cond. intertrial magazine entries0.30.42.0-1.40.61.0-0.4-0.40.4-0.4-0.5-0.50.5-0.2-0.41.40.7-0.40.40.0-0.50.50.1
Pavlov. Cond. lever-magazine prob. diff.0.40.51.50.8-0.2-0.5-0.5-0.30.9-0.3-0.5-0.50.5-0.5-0.5-1.2-0.60.5-1.0-1.00.5-0.3-1.2
Pavlov. Cond. response bias0.40.61.20.10.50.1-0.8-0.81.1-0.7-0.8-0.80.8-0.9-0.8-0.6-0.00.8-1.0-1.00.8-0.6-0.9
Time in closed arm before self-admin0.70.83.5-1.3-0.80.40.51.1-1.31.20.20.2-0.21.00.21.9-0.9-1.00.80.2-1.11.2-0.3
Time in closed arm after self-admin1.31.38.8-2.50.72.3-0.5-0.2-0.0-0.2-0.3-0.30.30.1-0.33.00.9-0.91.30.2-1.11.10.3
Time in open arm before self-admin1.31.45.11.61.2-0.7-0.9-1.41.5-1.4-0.4-0.40.4-1.3-0.4-2.30.81.5-1.2-0.61.5-1.60.0
Time in open arm after self-admin1.41.58.92.5-0.8-2.40.30.6-0.20.60.60.6-0.60.20.6-3.0-1.60.7-1.4-0.60.9-0.7-0.7
Bone: periosteal estimation1.12.28.32.0-1.9-2.91.01.5-1.01.50.50.4-0.40.60.4-2.0-2.90.9-1.5-0.81.2-0.9-1.5
Bone: periosteal perimeter1.93.110.02.5-2.7-3.01.72.3-1.82.31.21.2-1.21.51.2-2.1-3.2-0.2-0.7-0.20.20.1-1.0
Bone: post-yield work1.72.44.8-0.61.40.1-1.5-1.61.5-1.6-1.6-1.71.7-1.9-1.6-0.30.42.2-1.9-1.52.2-2.0-1.1
Progressive ratio test 1 active lever presses1.21.33.5-1.81.41.9-1.5-0.90.8-0.9-1.3-1.31.1-1.0-1.11.40.60.8-0.7-1.00.6-0.5-0.5
Progressive ratio test 1 breakpoint1.41.43.9-2.01.51.9-1.6-1.00.8-1.0-1.4-1.41.1-1.1-1.21.50.70.9-0.7-1.00.7-0.6-0.5
Progressive ratio test 1 inactive lever presses3.33.65.9-2.22.31.6-2.4-2.22.1-2.2-2.2-2.22.2-2.2-2.30.91.31.7-1.7-1.71.4-1.3-1.0
Progressive ratio test 2 active lever presses1.61.73.0-1.31.71.0-1.3-1.51.1-1.6-1.5-1.41.4-1.5-1.30.81.41.5-0.9-0.51.4-1.50.1
Progressive ratio test 2 breakpoint1.51.72.6-0.91.60.8-1.3-1.61.2-1.6-1.5-1.41.4-1.5-1.30.41.21.6-1.1-0.71.5-1.6-0.2
Progressive ratio test 2 inactive lever presses1.11.32.9-1.21.01.3-1.1-1.31.7-1.3-1.4-1.41.4-1.3-1.40.61.00.9-0.6-0.90.7-0.6-0.7
Incentive Sensitization - Responses1.51.53.2-0.71.30.0-1.3-1.10.7-1.1-1.6-1.51.5-1.4-1.40.30.41.8-1.5-1.01.8-1.7-0.6
Incentive Sensitization - Breakpoint1.51.52.8-0.61.30.1-1.3-1.20.9-1.2-1.6-1.51.5-1.4-1.40.20.51.7-1.4-1.01.6-1.6-0.6
Sum of active levers in priming session hrs 5-61.81.83.1-1.31.81.6-1.4-1.71.5-1.8-1.4-1.41.4-1.6-1.51.01.71.0-0.5-0.40.9-1.00.0
Progressive ratio0.40.52.1-0.50.4-1.50.10.1-0.80.10.60.6-0.6-0.00.50.0-0.21.1-0.50.41.2-1.40.6
Food seeking constrained by brief footshock0.40.52.81.7-0.8-0.10.1-0.00.80.00.30.2-0.20.10.0-1.7-0.4-0.6-0.1-0.4-0.60.8-0.8
Seeking ratio, punishment vs. effort0.70.92.91.3-0.41.5-0.5-0.71.7-0.6-0.8-0.80.8-0.5-0.8-1.10.3-0.80.1-0.8-1.01.3-1.1
Retroperitoneal fat weight0.20.52.20.10.8-1.00.3-0.3-0.8-0.40.20.2-0.2-0.40.2-0.30.61.0-0.40.71.2-1.51.2
Reaction time number correct3.65.28.32.4-2.9-1.72.92.6-2.22.62.82.8-2.82.72.6-1.3-1.6-2.12.01.9-1.91.71.0
Reaction time mean minus median2.02.75.90.81.3-0.3-1.4-2.22.4-2.2-1.3-1.31.3-2.1-1.3-1.91.22.0-1.8-1.12.0-2.0-0.8
Reaction time mean minus median AUC3.95.010.50.12.20.3-2.2-3.23.2-3.2-2.0-2.02.0-3.0-2.0-1.72.12.7-2.2-1.42.6-2.6-0.8
Reaction time num false alarms1.72.314.13.4-1.7-2.80.50.60.20.60.60.6-0.70.20.7-3.8-1.90.4-1.2-0.80.6-0.3-1.2
Reaction time num false alarms AUC1.92.615.03.5-1.9-2.80.60.80.00.80.70.7-0.80.40.8-3.9-2.20.2-1.2-0.80.4-0.1-1.3
Reaction time trials correct on left3.65.28.32.4-2.9-1.72.92.6-2.22.62.82.8-2.82.72.6-1.3-1.6-2.12.01.9-1.91.71.0
Reaction time trials on left3.55.07.92.4-2.8-1.72.82.5-2.12.52.82.8-2.72.62.5-1.3-1.5-2.11.91.8-1.81.61.0
Reaction time mean1.31.93.70.31.3-0.0-1.3-1.91.9-1.9-1.2-1.21.3-1.8-1.2-1.21.11.6-1.5-0.91.6-1.6-0.6
Reaction time mean AUC2.33.15.3-0.11.70.2-1.9-2.32.3-2.3-1.8-1.81.8-2.3-1.7-1.01.22.1-1.9-1.42.0-1.9-0.9
Median of all reaction times0.71.02.00.21.00.0-1.0-1.41.4-1.4-0.9-0.91.0-1.3-0.8-0.80.91.2-1.1-0.71.2-1.2-0.3
Reaction time omissions2.63.67.5-1.02.30.4-1.6-2.72.2-2.7-1.6-1.61.6-2.5-1.8-0.32.22.4-1.5-0.72.4-2.6-0.1
Reaction time false alarm rate1.31.87.11.8-0.1-1.8-0.9-0.61.0-0.6-0.8-0.80.7-1.0-0.6-2.7-1.11.4-2.1-1.61.5-1.2-1.6
Reaction time premature initiation rate1.62.13.61.0-1.5-0.61.71.9-1.71.91.91.9-1.81.91.8-0.3-1.2-1.31.31.0-1.11.10.8
Reaction time premature initiations4.25.99.32.2-2.8-1.53.03.0-2.63.03.13.1-3.03.02.9-1.1-1.9-2.22.11.8-1.91.81.1
Std. dev. reaction times1.92.76.31.00.9-0.4-1.5-2.12.5-2.0-1.4-1.41.4-2.0-1.4-2.10.81.8-2.0-1.51.8-1.6-1.3
Reaction time trials completed3.55.07.92.4-2.8-1.72.82.5-2.12.52.82.8-2.72.62.5-1.3-1.5-2.11.91.8-1.81.61.0
Reaction time trials AUC3.34.87.72.2-2.8-1.62.82.5-2.12.52.72.7-2.72.62.5-1.1-1.5-2.11.91.9-1.81.61.0
Run reversals in cocaine runway, females0.90.92.9-1.70.70.8-1.1-0.81.1-0.8-1.2-1.11.1-0.9-1.10.90.20.6-0.7-1.20.5-0.2-0.9
Run reversals in cocaine runway, males0.50.52.7-0.40.61.6-0.4-0.81.0-0.8-0.2-0.20.2-0.4-0.20.31.2-0.70.50.1-0.90.90.2
Latency to leave start box in cocaine runway0.70.82.9-1.31.00.00.4-0.1-1.0-0.20.20.2-0.2-0.00.31.51.00.80.31.30.9-1.41.7
Latency to leave start box in cocaine runway, F0.50.52.3-0.90.6-0.40.60.2-1.20.10.40.4-0.40.20.41.00.60.40.21.20.6-1.01.5
Latency to leave start box in cocaine runway, M0.30.31.1-0.80.90.8-0.2-0.50.1-0.5-0.2-0.20.2-0.3-0.01.11.00.20.40.40.1-0.30.7
Std. dev. time between licks in bursts4.45.211.8-0.42.2-0.3-2.2-2.42.1-2.4-2.3-2.32.3-2.8-2.2-1.00.83.4-3.1-1.93.4-3.3-1.3
Total sessions with >9 infusions2.22.45.8-2.12.22.4-1.8-2.01.8-2.0-1.5-1.41.4-1.7-1.41.31.90.8-0.6-0.70.6-0.6-0.1
Short access day 1 total inactive lever presses1.82.07.0-2.61.01.7-1.6-0.60.6-0.6-1.8-1.81.9-1.0-2.02.2-0.00.7-0.9-1.50.5-0.3-1.3
Short access day 10 total inactive lever presses0.30.31.31.00.3-0.7-0.1-0.60.6-0.6-0.0-0.10.2-0.5-0.3-1.10.30.6-0.5-0.10.7-0.7-0.0
Short access day 1 total infusions1.31.47.7-2.41.32.8-1.1-0.90.7-0.9-0.9-0.80.9-0.7-0.92.11.20.10.2-0.3-0.20.10.1
Short access day 10 total infusions1.51.69.0-3.00.92.9-1.1-0.20.2-0.2-1.0-0.90.8-0.3-0.82.80.3-0.40.2-0.7-0.60.8-0.5
Short access total infusions1.31.56.0-2.41.32.2-1.5-0.90.9-0.9-1.3-1.31.2-1.0-1.21.70.60.5-0.5-1.10.2-0.1-0.7
Short access day 1 locomotion0.10.10.7-0.40.50.8-0.3-0.20.1-0.20.20.2-0.1-0.10.10.30.5-0.30.30.1-0.40.30.4
Short access day 10 total locomotion0.80.92.2-0.50.00.90.60.3-0.50.31.11.1-1.20.81.20.70.8-1.21.51.2-1.31.11.3
Short access total locomotion0.30.31.2-0.80.71.1-0.5-0.50.6-0.50.10.1-0.2-0.20.20.40.9-0.30.40.1-0.50.50.4
One hour access (0.3 mA shock)0.60.72.7-1.60.90.8-0.7-0.50.2-0.6-0.8-0.80.9-0.6-0.91.50.60.8-0.4-0.30.8-0.80.0
Compulsive drug intake1.41.58.22.3-1.0-2.90.80.9-1.20.90.60.6-0.40.50.5-2.3-1.60.5-0.8-0.00.8-0.7-0.2
One hour access (shock baseline)1.82.19.3-3.01.53.0-1.1-1.11.0-1.1-0.9-0.90.9-0.8-0.93.01.80.00.60.0-0.20.10.4
Social response proportion0.40.41.90.4-0.5-0.1-0.3-0.21.2-0.2-0.5-0.50.5-0.3-0.7-0.9-0.6-0.0-0.7-1.0-0.10.4-1.4
Social responses1.01.38.12.5-1.5-1.60.40.40.80.50.70.7-0.70.30.5-2.8-1.3-0.1-0.5-0.7-0.00.3-1.1
Social time0.30.41.50.80.4-0.2-0.5-0.81.1-0.8-0.3-0.30.3-0.8-0.4-1.20.30.4-0.7-0.40.4-0.3-0.4
Soleus weight0.61.73.41.6-1.9-1.41.31.8-1.41.81.21.2-1.21.51.3-1.1-1.8-1.10.20.4-0.91.0-0.2
Bone: stiffness0.20.42.10.7-0.9-0.90.30.8-0.60.8-0.0-0.10.10.40.0-0.5-1.4-0.1-0.6-0.5-0.10.3-0.9
Tibialis anterior weight0.41.23.00.8-1.3-1.01.71.3-1.61.21.31.2-1.21.31.3-0.1-0.5-0.61.01.4-0.40.21.0
Time to tail flick, vehicle, before self-admin0.70.73.82.0-0.6-1.40.70.4-0.40.31.01.0-1.00.30.7-1.6-0.40.3-0.00.50.5-0.60.3
Time to tail flick, vehicle, after self-admin4.95.28.2-2.12.61.2-2.7-2.62.2-2.5-2.9-2.92.9-2.7-2.80.81.42.4-2.2-1.82.1-2.1-1.2
Time to tail flick, test, before self-admin2.92.87.3-2.72.41.6-1.6-1.91.0-1.9-1.6-1.61.6-1.8-1.62.32.01.5-0.9-0.41.3-1.50.5
Time to tail flick, test, after self-admin0.60.65.0-1.80.41.4-0.50.00.00.0-0.5-0.50.50.0-0.62.20.2-0.40.5-0.2-0.50.6-0.2
Delta time to tail flick, vehicle, before/after SA3.13.19.2-3.01.91.7-2.1-1.30.9-1.3-2.4-2.42.4-1.6-2.22.20.61.2-1.2-1.50.9-0.8-1.0
Delta time to tail flick, test, before/after SA0.90.81.40.3-1.0-0.11.01.2-1.01.20.90.9-0.91.20.80.3-0.7-1.11.10.7-1.01.00.3
Tibia length0.20.61.7-1.30.01.0-0.70.20.40.2-0.8-0.80.8-0.0-0.81.2-0.6-0.5-0.1-1.0-0.71.0-1.1
Ambulatory time before self-admin0.00.10.40.10.2-0.60.0-0.20.3-0.20.20.2-0.2-0.10.3-0.20.20.10.10.10.1-0.10.2
Ambulatory time after self-admin1.92.15.91.2-1.70.11.80.80.10.91.41.4-1.41.41.3-0.60.1-2.41.91.2-2.42.40.5
Bone: tissue strength0.50.51.6-1.30.50.9-0.8-0.20.5-0.2-0.9-0.90.9-0.3-0.81.0-0.0-0.1-0.0-0.7-0.30.5-0.7
Total heroin consumption0.50.61.00.8-0.8-0.60.80.8-0.70.81.01.0-1.00.81.0-0.8-0.5-0.80.50.5-0.70.70.4
Bone: trabecular number10.516.528.64.9-5.3-4.44.94.9-4.44.84.74.7-4.74.64.7-3.0-3.9-3.01.82.6-2.42.31.3
Bone: trabecular spacing6.17.913.3-3.53.53.5-3.7-3.23.4-3.1-3.4-3.43.4-2.9-3.42.22.41.3-1.1-2.30.7-0.4-1.4
Bone: trabecular thickness12.214.523.83.6-4.6-3.04.94.4-4.14.34.74.7-4.74.54.6-1.6-2.6-3.53.03.3-3.02.72.1
Bone: trabecular tissue density0.81.24.8-2.21.31.7-0.6-0.80.4-0.9-0.7-0.70.7-0.5-0.62.11.6-0.41.00.5-0.50.30.8
Water consumed over 24 hours1.92.26.22.0-2.1-2.52.01.7-1.71.71.51.5-1.51.51.5-1.3-1.8-0.50.10.8-0.20.10.2
Number of responses in last shaping day1.51.57.7-2.51.42.8-0.4-0.60.1-0.70.10.1-0.0-0.2-0.02.71.9-0.10.70.8-0.2-0.11.5