Hub : Genes

Lcat

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain isoform ratio XM_006255441.3 0.25 0.12 2.5e-15 0.14 0.16 0.14 0.16 5.2e-13 2.7e-14 3.2e-13 1.9e-14
2 Brain isoform ratio XM_039097472.2 0.08 0.07 7.7e-04 0.03 0.03 0.02 0.03 4.8e-04 5.4e-04 3.1e-03 7.7e-04
3 Brain mRNA stability Lcat 0.15 0.07 2.3e-15 0.15 0.16 0.16 0.15 1.4e-13 1.1e-14 2.7e-14 4.2e-14
4 Liver gene expression Lcat 0.03 0.02 2.1e-03 0.02 0.02 0 0.02 9.0e-04 2.6e-03 1.2e-01 3.6e-03
5 RMTg gene expression Lcat 0.26 0.15 4.0e-05 0.26 0.16 0.19 0.24 1.1e-07 5.2e-05 8.5e-06 4.2e-07
6 NAcc gene expression Lcat 0.26 0.06 0.0e+00 0.24 0.24 0.25 0.25 8.7e-37 1.2e-35 4.5e-37 8.2e-37
7 OFC gene expression Lcat 0.31 0.16 3.2e-05 0.25 0.17 0.21 0.24 1.5e-06 6.2e-05 8.6e-06 1.9e-06
8 Brain gene expression Lcat 0.34 0.1 0.0e+00 0.27 0.27 0.27 0.27 1.2e-25 8.2e-25 2.7e-25 2.5e-25
9 LHb gene expression Lcat 0.4 0.16 3.1e-06 0.2 0.22 0.15 0.21 2.0e-05 7.3e-06 2.0e-04 9.5e-06
10 PL gene expression Lcat 0.44 0.22 0.0e+00 0.25 0.21 0.23 0.24 1.7e-27 1.1e-22 5.9e-25 5.5e-26
11 PL mRNA stability Lcat 0.05 0.04 4.0e-03 0.02 0.02 0.02 0.02 2.0e-03 3.8e-03 3.9e-03 2.4e-03
12 BLA gene expression Lcat 0.22 0.12 2.1e-05 0.14 0.09 0.12 0.13 1.2e-07 1.3e-05 4.3e-07 3.5e-07
13 Brain isoform ratio NM_017024.2 0.29 0.12 8.5e-14 0.15 0.15 0.13 0.15 5.2e-14 1.8e-13 2.9e-12 1.0e-13
14 IC gene expression Lcat 0.57 0.17 2.1e-05 0.16 0.13 0.11 0.16 3.9e-07 3.2e-06 3.3e-05 3.8e-07
15 pVTA gene expression Lcat 0.36 0.11 0.0e+00 0.26 0.24 0.25 0.25 8.2e-21 3.9e-19 3.1e-20 4.4e-20
16 IL gene expression Lcat 0.48 0.16 1.1e-07 0.3 0.11 0.26 0.26 5.2e-08 1.5e-03 7.0e-07 5.0e-07
17 Brain alternative TSS XM_006255441.3 0.31 0.13 7.8e-16 0.18 0.16 0.15 0.16 9.2e-17 1.2e-14 1.5e-13 3.7e-15
18 Brain alternative TSS NM_017024.2 0.3 0.13 8.9e-16 0.18 0.16 0.15 0.16 3.8e-16 1.1e-14 7.6e-14 5.4e-15
19 NAcc alternative TSS XM_006255441.3 0.04 0.04 9.2e-03 0.02 0.01 0.02 0.02 2.2e-04 3.8e-02 7.0e-04 3.2e-04
20 pVTA mRNA stability Lcat 0.03 0.02 5.6e-03 -0 0 -0 -0 6.6e-01 1.5e-01 9.1e-01 5.9e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.00.00.10.40.3-0.30.0-0.3-0.2-0.2-0.2-0.2-0.3-0.2-0.1-0.2-0.2-0.1-0.2-0.10.1-0.1-0.2
Area under the delay curve0.20.30.5-0.70.0-0.20.4-0.7-0.4-0.6-0.7-0.4-0.7-0.6-0.7-0.6-0.6-0.5-0.70.4-0.40.4-0.2
BMI with tail0.20.60.90.60.8-0.70.9-0.9-0.8-0.8-0.9-0.5-0.9-0.8-1.0-0.9-0.8-0.7-0.80.9-0.90.70.5
BMI without tail0.10.20.40.20.3-0.20.5-0.6-0.5-0.6-0.6-0.2-0.7-0.6-0.5-0.7-0.6-0.4-0.40.6-0.60.40.5
Body weight0.10.61.31.21.2-1.11.0-0.8-0.7-0.6-0.6-0.7-0.8-0.6-1.0-0.7-0.6-0.5-0.80.6-0.60.60.2
Weight adjusted by age0.00.00.2-0.10.00.1-0.00.10.20.10.10.00.20.00.10.20.00.30.1-0.40.4-0.3-0.4
Bone surface0.50.82.01.31.2-1.40.8-0.9-0.9-0.8-0.8-1.1-0.9-0.8-0.8-0.8-0.8-0.8-0.90.7-0.70.8-0.6
Bone volume0.30.51.51.21.0-1.10.5-0.7-0.7-0.5-0.5-0.9-0.7-0.6-0.6-0.6-0.5-0.6-0.60.3-0.30.4-1.1
Breakpoint value in progressive ratio session2.22.63.3-1.6-1.51.6-1.71.81.61.61.61.61.71.71.71.61.71.61.7-1.81.8-1.80.9
Number of licking bursts0.30.51.10.70.9-1.00.9-0.7-0.7-0.6-0.6-0.5-0.5-0.6-0.6-0.6-0.5-0.6-0.70.7-0.70.70.9
Context. condit. distance diff. score0.60.71.0-0.7-0.70.5-0.90.90.90.90.90.70.90.91.01.00.90.90.9-0.90.9-0.90.4
Locomotion velocity, session 10.50.61.00.40.3-0.60.5-0.8-0.8-0.8-0.9-0.5-0.8-0.8-0.7-0.8-0.9-1.0-0.90.8-0.80.90.3
Locomotion distance, session 10.10.10.7-0.3-0.50.3-0.30.30.30.30.30.50.20.30.40.30.30.10.2-0.40.4-0.30.8
Locomotion velocity, session 21.51.84.6-1.2-1.31.1-1.11.31.31.31.31.51.31.31.31.31.31.21.3-1.31.3-1.32.1
Locomotion distance, session 20.30.53.0-0.4-0.70.5-0.50.60.50.60.60.80.50.60.60.50.60.50.5-0.70.7-0.61.7
Locomotion velocity, session 30.00.10.5-0.5-0.30.3-0.3-0.10.1-0.1-0.10.2-0.1-0.10.1-0.1-0.1-0.0-0.0-0.00.0-0.10.7
Locomotion distance, session 30.30.40.8-0.5-0.40.4-0.90.60.70.60.60.40.60.60.60.60.70.70.6-0.60.6-0.70.1
Stereotopy head waving bouts, day 30.30.30.60.30.5-0.40.5-0.6-0.6-0.7-0.7-0.5-0.5-0.7-0.5-0.6-0.6-0.7-0.50.7-0.70.8-0.3
Stereotopy head waving duration, day 30.50.60.70.80.8-0.80.8-0.7-0.8-0.8-0.8-0.7-0.7-0.8-0.7-0.7-0.8-0.8-0.70.8-0.80.8-0.1
Locomotion velocity, session 70.20.20.9-0.3-0.40.3-0.80.40.40.40.40.00.40.40.50.40.40.40.5-0.40.4-0.4-0.9
Locomotion distance, session 70.30.40.9-0.5-0.40.4-1.00.60.60.60.60.30.60.60.70.50.60.60.7-0.60.6-0.6-0.5
Stereotopy head waving bouts, day 70.20.30.40.40.6-0.60.5-0.5-0.5-0.6-0.6-0.5-0.5-0.6-0.5-0.4-0.6-0.5-0.50.6-0.60.6-0.2
Stereotopy head waving duration, day 71.11.41.81.01.1-1.11.1-1.1-1.2-1.2-1.2-1.1-1.2-1.2-1.2-1.1-1.2-1.3-1.11.3-1.31.3-0.4
Locomotion velocity, session 80.10.11.1-0.1-0.1-0.10.2-0.0-0.00.00.00.2-0.00.00.00.00.0-0.0-0.1-0.10.10.01.1
Locomotion distance, session 80.91.32.7-1.0-1.10.9-1.11.11.11.11.11.21.11.11.21.11.11.11.0-1.21.2-1.11.6
Degree of sensitization distance0.00.00.50.10.1-0.00.1-0.0-0.1-0.1-0.1-0.2-0.0-0.1-0.1-0.1-0.1-0.10.00.1-0.10.1-0.7
Degree of sensitization stereotypy0.50.50.60.70.8-0.70.7-0.7-0.7-0.8-0.8-0.7-0.8-0.8-0.7-0.7-0.8-0.7-0.70.8-0.80.8-0.5
Conditioned locomotion0.30.41.41.21.0-1.20.5-0.3-0.6-0.4-0.4-0.7-0.4-0.4-0.4-0.4-0.3-0.5-0.30.5-0.50.6-0.2
Cocaine response after cond. corrected2.42.93.71.31.3-1.11.9-1.8-1.8-1.8-1.8-1.7-1.8-1.8-1.8-1.8-1.8-1.8-1.71.7-1.71.7-1.9
Cocaine response after cond. not corrected1.72.02.70.80.9-0.61.7-1.5-1.5-1.5-1.5-1.2-1.5-1.5-1.6-1.5-1.6-1.5-1.51.4-1.41.4-1.3
Cocaine response before conditioning0.70.82.8-1.2-1.01.0-0.90.70.90.80.81.20.70.80.80.70.70.80.7-0.80.8-0.81.7
Saline control response3.14.15.92.32.2-2.42.2-2.0-2.0-1.9-2.0-1.8-2.0-2.0-2.2-2.0-2.0-1.9-2.12.0-2.02.0-0.0
Bone: connectivity density0.10.10.4-0.2-0.20.1-0.40.20.30.30.30.40.20.30.30.30.30.30.3-0.40.4-0.30.7
Bone: cortical apparent density0.20.21.0-1.0-0.60.7-0.50.40.50.50.50.60.50.50.40.50.50.50.4-0.30.3-0.30.1
Bone: cortical area0.10.22.20.50.4-0.50.2-0.2-0.2-0.1-0.1-0.6-0.2-0.1-0.3-0.1-0.1-0.2-0.30.2-0.20.2-1.5
Bone: cortical porosity1.11.22.2-0.7-1.10.8-1.51.21.11.11.11.01.21.11.21.11.11.11.2-1.01.0-1.00.6
Bone: cortical porosity0.70.81.8-0.6-0.90.7-1.31.00.90.90.90.80.90.91.00.90.90.81.0-0.70.7-0.80.3
Bone: cortical thickness0.10.11.20.30.4-0.30.2-0.3-0.2-0.2-0.2-0.5-0.2-0.2-0.3-0.2-0.2-0.2-0.30.3-0.30.3-1.1
Bone: cortical thickness1.21.41.9-0.4-0.70.7-1.21.31.21.31.30.61.21.31.21.31.31.41.4-1.31.3-1.4-0.8
Bone: cortical tissue density0.20.31.1-1.0-0.60.7-0.50.40.50.50.50.60.50.50.40.50.50.40.4-0.30.3-0.30.2
Condit. Reinf. active minus inactive responses2.73.04.9-2.1-2.22.1-2.11.81.71.71.71.61.81.71.81.71.71.61.8-1.41.4-1.40.0
Condit. Reinf. active-inactive response ratio2.12.23.7-1.9-1.91.9-1.91.51.51.41.41.41.51.51.51.51.41.41.6-1.21.2-1.20.1
Condit. Reinf. active responses2.53.14.5-2.0-2.12.0-2.01.91.81.71.71.61.91.71.91.81.71.61.9-1.51.5-1.50.2
Condit. Reinf. inactive responses0.40.50.8-0.5-0.60.7-0.60.90.70.70.70.60.80.70.80.70.70.70.8-0.80.8-0.7-0.1
Incentive salience index mean1.82.23.5-1.7-1.91.7-1.91.61.51.41.41.41.61.51.61.51.41.31.6-1.21.2-1.20.2
Condit. Reinf. lever presses0.20.20.5-0.5-0.70.4-0.70.60.50.40.40.40.60.50.60.50.40.40.6-0.30.3-0.20.2
Condit. Reinf. active minus inactive responses0.50.71.21.01.0-0.91.0-0.8-0.7-0.8-0.7-0.9-0.8-0.7-0.9-0.7-0.7-0.6-0.80.6-0.60.6-1.1
Condit. Reinf. active-inactive response ratio0.60.71.60.91.0-0.80.9-0.8-0.8-0.8-0.7-1.0-0.7-0.8-0.9-0.7-0.7-0.7-0.70.6-0.60.7-1.3
Condit. Reinf. active responses0.10.10.40.60.6-0.60.5-0.4-0.3-0.3-0.3-0.4-0.4-0.3-0.5-0.3-0.3-0.2-0.40.1-0.10.2-0.4
Condit. Reinf. inactive responses0.40.60.7-0.6-0.80.6-0.70.70.80.70.80.80.60.80.70.70.70.80.7-0.80.8-0.90.8
Condit. Reinf. lever presses4.66.37.3-2.2-2.22.1-2.32.52.62.62.62.62.42.62.52.62.62.62.4-2.72.7-2.72.5
Condit. Reinf. lever reinforcers received0.10.10.20.1-0.0-0.0-0.00.20.30.30.30.20.20.30.10.30.30.40.2-0.40.4-0.40.1
Conditioned reinforcement - actives0.10.20.8-0.8-0.90.9-0.60.30.40.40.40.60.30.30.40.40.30.40.3-0.40.4-0.20.4
Conditioned reinforcement - inactives0.30.50.80.70.7-0.60.6-0.8-0.8-0.5-0.5-0.7-0.7-0.6-0.6-0.7-0.6-0.7-0.80.8-0.80.9-0.8
Conditioned locomotion0.81.11.51.21.1-1.11.1-1.2-1.1-0.9-0.9-1.1-1.0-0.9-1.0-0.9-0.9-1.0-1.21.0-1.01.0-0.8
Patch foraging indifference point 0 sec1.73.14.82.02.2-2.21.8-1.8-1.8-1.7-1.8-1.9-1.8-1.7-1.8-1.8-1.6-1.7-1.71.6-1.61.6-1.0
Patch foraging indifference point AUC0.40.51.91.41.2-1.30.8-0.7-0.6-0.6-0.5-0.6-0.6-0.5-0.6-0.5-0.5-0.4-0.40.5-0.50.50.4
Delay disc. indifference point, 0s delay0.10.11.0-1.0-0.50.5-0.1-0.20.1-0.1-0.10.4-0.1-0.1-0.2-0.1-0.20.0-0.2-0.10.10.00.9
Delay disc. indifference point, 16s delay0.30.30.50.00.0-0.30.5-0.7-0.5-0.5-0.7-0.5-0.6-0.5-0.5-0.6-0.6-0.6-0.70.6-0.60.5-0.6
Delay disc. indifference point, 2s delay0.30.40.6-0.10.4-0.70.6-0.8-0.5-0.6-0.7-0.6-0.7-0.7-0.8-0.6-0.7-0.5-0.70.6-0.60.7-0.2
Delay disc. indifference point, 24s delay0.00.00.1-0.3-0.30.0-0.20.10.10.1-0.00.10.20.20.30.20.20.10.20.0-0.00.00.1
Delay disc. indifference point, 4s delay0.10.11.3-1.1-0.10.30.0-0.20.2-0.10.00.1-0.2-0.1-0.3-0.2-0.10.2-0.3-0.30.3-0.3-0.1
Delay disc. indifference point, 8s delay0.20.30.6-0.70.1-0.10.4-0.6-0.4-0.5-0.7-0.4-0.6-0.6-0.7-0.6-0.6-0.5-0.60.3-0.30.3-0.8
Indifference point function ln k0.10.21.7-0.3-0.20.40.1-0.3-0.2-0.2-0.2-0.3-0.4-0.2-0.3-0.3-0.2-0.3-0.40.2-0.20.3-1.3
Indifference point function log k0.10.21.7-0.3-0.20.40.1-0.3-0.2-0.2-0.2-0.3-0.4-0.2-0.3-0.3-0.2-0.3-0.40.2-0.20.3-1.3
Patch foraging total patch changes 0 sec1.52.94.62.12.2-2.11.8-1.7-1.7-1.6-1.7-1.8-1.7-1.6-1.7-1.7-1.6-1.6-1.61.5-1.51.5-1.0
Patch foraging total patch changes 12 sec0.91.23.21.71.6-1.81.1-0.9-1.0-1.0-1.0-1.0-1.0-0.9-0.9-0.9-0.9-0.9-0.80.9-0.90.90.3
Patch foraging total patch changes 18 sec0.50.72.91.71.5-1.50.9-0.6-0.7-0.6-0.6-1.1-0.7-0.6-0.7-0.6-0.5-0.5-0.50.4-0.40.4-1.1
Patch foraging total patch changes 24 sec0.10.21.80.20.3-0.4-0.20.40.30.30.30.40.30.30.40.40.30.40.5-0.50.5-0.51.3
Patch foraging total patch changes 6 sec1.01.53.11.41.7-1.81.3-1.3-1.2-1.2-1.2-1.0-1.3-1.2-1.3-1.2-1.1-1.1-1.11.0-1.01.00.4
Patch foraging time to switch 0 sec0.51.02.2-1.5-1.21.0-1.11.00.90.90.91.11.10.81.20.90.80.80.9-0.80.8-0.81.4
Patch foraging water rate 0 sec0.92.04.62.11.6-1.61.5-1.4-1.5-1.3-1.3-1.5-1.4-1.2-1.5-1.3-1.1-1.3-1.21.3-1.31.3-1.2
Patch foraging water rate 12 sec0.10.20.50.70.7-0.40.6-0.5-0.3-0.3-0.3-0.3-0.5-0.2-0.7-0.4-0.2-0.2-0.5-0.00.00.0-0.5
Patch foraging water rate 18 sec0.10.20.6-0.00.3-0.0-0.10.20.40.40.40.10.10.40.20.30.40.50.3-0.70.7-0.7-0.5
Patch foraging water rate 24 sec0.10.11.60.20.00.10.00.00.0-0.1-0.0-0.2-0.1-0.00.00.1-0.00.10.2-0.20.2-0.2-1.3
Patch foraging water rate 6 sec0.30.44.21.10.9-0.60.6-0.3-0.4-0.3-0.3-0.8-0.3-0.2-0.6-0.2-0.1-0.1-0.10.0-0.00.1-2.0
Seeking ratio, delayed vs. immediate footshock2.73.44.51.81.6-1.91.7-1.8-2.0-1.8-1.8-2.1-1.6-1.7-1.7-1.7-1.7-2.1-1.52.1-2.12.1-1.6
Distance traveled before self-admin0.40.62.0-0.50.4-0.5-0.50.90.60.90.9-0.30.60.80.70.80.90.70.8-0.60.6-0.6-1.4
Distance traveled after self-admin0.00.10.2-0.30.2-0.3-0.20.4-0.00.20.1-0.20.30.20.20.20.2-0.20.40.2-0.20.2-0.3
Extensor digitorum longus weight1.66.37.6-1.8-2.22.2-2.62.62.62.72.72.42.62.62.72.72.62.72.6-2.82.8-2.71.1
Bone: elastic displacement2.42.84.21.71.8-1.41.8-1.7-1.6-1.7-1.7-1.8-1.7-1.7-1.7-1.7-1.6-1.5-1.71.5-1.51.5-2.1
Bone: elastic work0.81.03.91.11.1-0.81.0-1.0-0.9-0.8-0.8-1.1-0.9-0.9-1.0-0.9-0.8-0.8-1.00.8-0.80.7-2.0
Bone: endosteal estimation0.00.11.00.30.1-0.1-0.10.1-0.10.00.0-0.30.00.00.10.00.1-0.1-0.1-0.00.00.0-1.0
Bone: endosteal perimeter0.00.11.00.40.0-0.2-0.40.30.10.20.2-0.20.20.20.20.20.30.20.0-0.20.2-0.1-1.0
Epididymis fat weight0.82.86.12.52.3-2.21.9-1.4-1.5-1.3-1.2-2.0-1.5-1.4-1.7-1.5-1.3-1.2-1.61.2-1.21.2-2.3
Delta time in closed arm before/after self-admin0.40.40.60.20.2-0.50.6-0.5-0.7-0.8-0.7-0.5-0.7-0.8-0.6-0.8-0.8-0.8-0.40.7-0.70.70.0
Delta time in open arm before/after self-admin0.10.10.40.10.40.10.0-0.20.20.10.1-0.00.10.10.00.20.10.3-0.2-0.20.2-0.2-0.6
Diff in mean of infusions in LGA sessions1.01.21.9-1.1-1.00.9-1.11.21.11.00.91.11.01.11.21.11.11.11.2-1.21.2-1.21.4
Delay discount exponential model param0.10.20.50.70.10.1-0.30.60.30.40.50.20.50.40.50.50.40.30.6-0.20.2-0.3-0.0
Extinction: sum of active levers before priming0.30.30.9-0.2-0.50.9-0.50.40.60.60.50.70.50.50.40.40.50.60.4-0.80.8-0.80.4
Active lever presses in extinction session 60.00.00.3-0.2-0.1-0.00.00.0-0.2-0.1-0.1-0.3-0.1-0.1-0.1-0.1-0.1-0.40.00.1-0.10.1-0.5
Bone: final force1.72.83.3-1.6-1.71.5-1.81.81.71.81.81.51.81.81.71.81.81.61.6-1.81.8-1.70.2
Bone: final moment0.71.11.4-1.0-1.11.0-1.21.11.01.21.20.91.11.11.11.11.10.90.9-1.11.1-1.0-0.1
Food consumed during 24 hour testing period0.10.20.40.1-0.0-0.1-0.30.50.40.60.60.30.60.60.30.60.60.50.4-0.50.5-0.50.3
Glucose0.40.62.3-1.5-1.01.2-0.90.60.70.60.60.90.60.60.70.60.60.60.7-0.60.6-0.60.6
Heart weight0.20.20.50.20.3-0.20.5-0.6-0.4-0.6-0.6-0.2-0.7-0.6-0.5-0.6-0.7-0.4-0.50.4-0.40.40.1
Delay discount hyperbolic model param0.10.20.80.90.10.0-0.30.60.20.40.50.10.50.40.50.50.40.30.6-0.20.2-0.2-0.1
Intermittent access intake day 1-15 change0.71.52.8-1.7-1.31.5-1.31.01.21.21.21.41.01.21.11.11.21.11.1-1.21.2-1.11.1
Intermittent access intake escalation0.71.42.8-1.7-1.41.5-1.21.01.11.21.21.40.91.21.11.01.11.11.1-1.21.2-1.01.1
Intermittent access intake escalation 20.40.41.1-1.1-0.80.9-0.70.50.60.70.70.80.40.70.60.50.60.60.6-0.60.6-0.40.5
Intermitt. access day 1 inactive lever presses0.10.41.10.10.1-0.20.5-0.7-0.6-0.8-0.7-0.2-0.6-0.8-0.6-0.6-0.8-0.7-0.90.8-0.80.71.0
Intermitt. access day 15 inactive lever presses0.00.10.2-0.2-0.40.2-0.30.20.20.50.40.10.30.40.30.30.40.20.2-0.00.0-0.2-0.1
Intermitt. access escalation Index0.40.61.00.70.6-0.70.8-0.6-0.9-0.9-0.9-0.8-0.6-0.9-0.8-0.8-0.8-1.0-0.70.8-0.80.9-0.3
Intermittent access day 1 total infusions0.81.42.30.50.2-0.40.9-1.4-1.3-1.2-1.3-0.8-1.3-1.3-1.2-1.2-1.3-1.5-1.31.5-1.51.50.2
Intermittent access day 15 total infusions0.20.21.3-1.1-1.01.0-0.4-0.30.10.10.10.6-0.20.00.0-0.0-0.0-0.1-0.10.0-0.00.20.8
Intermittent access terminal intake (last 3 days)0.50.62.4-1.5-1.51.5-0.90.30.60.60.61.10.30.50.60.50.50.50.5-0.40.4-0.31.0
Intermittent access total infusions0.30.31.6-1.2-1.31.2-0.60.00.30.30.30.70.10.30.30.20.20.20.3-0.20.2-0.10.6
Intermittent access day 1 locomotion4.05.17.01.81.6-1.82.1-2.6-2.4-2.3-2.3-2.1-2.4-2.3-2.3-2.2-2.3-2.5-2.62.6-2.62.5-1.0
Intermittent access day 15 total locomotion1.42.64.11.11.3-1.11.6-2.0-1.7-1.7-1.7-1.4-1.8-1.7-1.7-1.6-1.7-1.8-2.01.6-1.61.8-0.7
Intermittent access total locomotion1.92.33.60.90.8-0.81.4-1.9-1.7-1.5-1.6-1.4-1.7-1.5-1.6-1.5-1.6-1.8-1.81.7-1.71.9-1.0
Intermittent access standard deviation0.30.60.80.70.8-0.70.8-0.8-0.8-0.8-0.6-0.7-0.9-0.8-0.8-0.9-0.8-0.8-0.70.7-0.70.7-0.6
Left kidney weight3.014.116.2-3.2-3.13.1-3.63.84.04.03.93.93.84.03.53.94.04.03.8-3.93.9-4.03.3
Right kidney weight3.515.819.1-3.3-3.23.3-3.74.04.34.34.24.14.04.23.84.04.34.44.0-4.34.3-4.33.2
Cocaine induced anxiety3.34.75.72.22.3-2.22.3-2.3-2.2-2.3-2.4-2.0-2.2-2.3-2.3-2.3-2.2-2.1-2.42.0-2.02.0-0.9
Post-drug Anxiety1.31.42.41.01.2-1.01.3-1.5-1.2-1.3-1.3-0.9-1.5-1.2-1.4-1.4-1.2-1.1-1.50.9-0.91.0-0.0
Baseline Anxiety0.91.02.2-1.5-1.31.3-1.00.70.91.01.11.10.71.00.90.81.00.90.9-0.90.9-0.90.9
Tail length0.00.10.20.0-0.30.1-0.30.20.20.20.20.30.20.30.30.10.20.20.3-0.30.3-0.10.4
Length with tail0.00.10.40.40.3-0.3-0.10.20.40.50.60.20.20.50.10.30.50.50.2-0.60.6-0.40.3
Length without tail0.10.41.41.01.2-1.00.8-0.7-0.4-0.4-0.3-0.5-0.6-0.4-0.9-0.5-0.4-0.3-0.70.1-0.10.3-0.2
Times rat made contact with spout0.60.71.30.91.0-1.20.6-0.8-0.9-0.8-0.8-1.0-0.7-0.7-0.7-0.7-0.7-0.9-0.81.0-1.00.9-0.5
Lifetime Intake0.20.31.5-1.1-1.21.2-0.60.10.30.30.30.70.20.30.30.20.20.20.3-0.10.1-0.10.4
Liver weight, left0.10.10.50.40.5-0.60.2-0.2-0.2-0.1-0.1-0.1-0.1-0.1-0.1-0.2-0.1-0.2-0.10.3-0.30.20.7
Liver weight, right0.10.10.50.70.6-0.70.4-0.4-0.2-0.2-0.2-0.1-0.3-0.2-0.4-0.3-0.2-0.1-0.50.1-0.10.10.6
Locomotor activity1.21.83.41.81.8-1.81.5-1.3-1.2-1.2-1.1-1.6-1.2-1.2-1.3-1.2-1.1-1.1-1.31.0-1.01.0-1.8
Locomotor testing distance1.42.63.51.91.7-1.81.7-1.7-1.6-1.4-1.4-1.8-1.6-1.5-1.6-1.5-1.4-1.5-1.61.5-1.51.6-1.7
Locomotor testing rearing0.10.21.60.80.5-0.40.3-0.1-0.10.00.1-0.4-0.1-0.0-0.2-0.00.00.1-0.0-0.20.2-0.1-1.3
Locomotion in novel chamber2.73.53.91.81.7-1.92.0-1.8-1.9-1.9-1.8-2.0-2.0-1.9-1.9-1.9-1.9-1.9-1.81.9-1.91.9-1.7
Locomotion in novel chamber post-restriction1.72.84.01.41.6-1.61.8-1.7-1.7-1.5-1.5-1.8-1.8-1.6-1.8-1.7-1.5-1.7-2.01.7-1.71.7-1.5
Fecal boli incidents, locomotor time 10.20.31.10.91.1-0.90.6-0.4-0.6-0.5-0.5-0.4-0.4-0.6-0.4-0.4-0.6-0.5-0.40.4-0.40.40.2
Change in fecal boli incidents, locomotor task0.20.21.7-0.7-0.40.5-0.30.10.40.30.30.70.20.40.00.20.30.30.1-0.40.4-0.11.3
Time >=10cm from walls, locomotor time 10.50.50.90.20.8-0.60.7-0.8-0.8-0.8-0.8-0.6-0.8-0.7-0.9-0.8-0.7-0.8-0.80.7-0.70.50.1
Bouts of movement, locomotor time 10.70.71.20.80.6-0.60.7-0.8-0.9-1.0-1.0-0.5-0.9-1.1-0.6-0.9-1.1-1.0-0.81.0-1.00.90.5
Total resting periods, locomotor time 10.40.40.70.40.4-0.30.5-0.5-0.7-0.8-0.7-0.3-0.7-0.8-0.3-0.7-0.8-0.7-0.50.8-0.80.80.6
Rest time, locomotor task time 10.50.61.20.40.2-0.20.5-0.8-0.8-1.0-1.0-0.2-0.9-1.0-0.5-0.9-1.1-1.0-0.70.8-0.80.91.0
Distance moved, locomotor task time 10.10.11.1-0.00.3-0.20.2-0.10.10.10.2-0.30.00.2-0.20.00.20.3-0.1-0.10.1-0.3-1.0
Vertical activity count, locomotor time 10.10.34.00.50.6-0.50.4-0.3-0.1-0.1-0.1-0.7-0.1-0.1-0.2-0.10.00.1-0.3-0.00.0-0.0-2.0
Time >=10cm from walls, locomotor time 20.20.30.7-0.8-0.30.7-0.50.30.50.50.60.50.50.50.20.50.50.50.3-0.60.6-0.70.3
Bouts of movement, locomotor time 20.30.51.2-0.8-1.10.8-0.90.90.70.70.60.80.70.70.70.70.70.50.8-0.50.5-0.70.7
Total resting periods, locomotor time 20.50.81.4-0.9-1.21.0-1.01.00.80.90.81.00.90.80.90.90.80.71.0-0.70.7-0.91.0
Rest time, locomotor task time 20.20.21.4-0.4-0.50.6-0.60.40.30.20.20.60.30.10.70.30.10.10.4-0.30.3-0.21.2
Distance moved, locomotor task time 20.50.64.10.61.0-0.70.8-0.8-0.4-0.3-0.3-0.9-0.6-0.3-1.0-0.6-0.2-0.2-0.80.4-0.40.2-2.0
Vertical activity count, locomotor time 20.50.63.31.01.0-0.90.9-0.9-0.5-0.5-0.5-1.0-0.7-0.4-0.9-0.7-0.4-0.4-0.90.5-0.50.3-1.8
Light reinforcement 10.61.63.92.01.6-1.91.3-0.9-1.2-0.9-0.9-1.7-0.9-0.9-1.1-0.9-0.8-1.1-0.81.0-1.01.1-1.9
Light reinforcement 21.21.83.01.31.6-1.71.3-1.2-1.3-1.3-1.3-1.7-1.1-1.2-1.2-1.2-1.2-1.3-1.11.3-1.31.3-1.7
Bone: marrow area0.00.11.00.30.1-0.1-0.10.1-0.10.00.0-0.3-0.00.00.10.00.1-0.1-0.10.0-0.00.1-1.0
Bone: maximum diameter0.20.31.80.80.6-0.70.5-0.5-0.5-0.3-0.3-0.7-0.4-0.4-0.5-0.4-0.3-0.4-0.60.5-0.50.5-1.3
Bone: maximum force0.50.91.2-0.9-0.90.8-1.11.00.91.01.00.71.01.01.01.01.00.90.9-1.01.0-1.0-0.2
Bone: maximum moment0.10.10.4-0.3-0.30.3-0.50.30.30.40.40.10.30.40.30.40.40.20.2-0.30.3-0.3-0.6
Mean time between licks in bursts0.00.10.8-0.00.0-0.0-0.20.00.10.10.1-0.10.10.10.10.10.10.10.1-0.20.2-0.2-0.9
Mean num. licks in bursts0.10.11.8-0.0-0.20.3-0.60.40.20.20.2-0.10.20.20.20.20.20.10.3-0.20.2-0.2-1.3
Cd content in liver0.10.10.2-0.2-0.20.30.00.30.30.30.30.20.20.20.20.30.20.40.3-0.30.3-0.4-0.3
Co content in liver0.10.11.3-0.2-0.10.4-0.10.20.30.30.3-0.00.30.20.20.30.20.30.2-0.40.4-0.5-1.1
Cu content in liver0.81.01.4-1.1-1.11.1-1.00.91.00.90.91.10.90.90.70.90.91.00.9-1.21.2-1.21.0
Fe content in liver1.51.83.01.41.7-1.51.5-1.2-1.4-1.4-1.4-1.5-1.2-1.3-1.3-1.2-1.3-1.4-1.21.2-1.21.1-1.3
K content in liver0.00.00.2-0.20.10.2-0.1-0.2-0.1-0.2-0.20.2-0.2-0.2-0.2-0.2-0.2-0.1-0.2-0.10.1-0.10.5
Mg content in liver0.70.71.00.80.9-0.70.6-1.0-0.9-0.9-1.0-0.7-0.9-0.9-0.9-0.9-0.9-0.9-0.90.7-0.70.70.0
Mn content in liver1.21.31.71.11.2-1.10.9-1.3-1.2-1.3-1.3-1.1-1.2-1.2-1.3-1.3-1.2-1.2-1.21.1-1.11.2-0.5
Na content in liver0.30.41.00.01.0-0.20.5-0.7-0.6-0.7-0.7-0.4-0.7-0.6-0.7-0.7-0.6-0.6-0.70.4-0.40.5-0.2
Rb content in liver0.10.10.8-0.2-0.90.4-0.50.10.20.10.10.40.10.00.20.1-0.00.10.1-0.50.5-0.40.5
Se content in liver0.50.52.8-0.2-0.50.6-0.80.80.50.60.60.10.80.70.70.80.80.60.8-0.70.7-0.7-1.7
Sr content in liver0.40.30.80.90.7-0.90.4-0.4-0.5-0.5-0.5-0.6-0.4-0.4-0.4-0.4-0.4-0.5-0.40.8-0.80.8-0.2
Zn content in liver2.12.32.9-1.5-1.31.7-1.51.61.51.61.51.31.61.51.61.61.51.51.6-1.71.7-1.7-0.1
Bone: minimum diameter0.20.32.60.60.3-0.40.3-0.4-0.5-0.4-0.4-0.7-0.4-0.3-0.4-0.3-0.3-0.5-0.50.2-0.20.3-1.6
Time in familiar zone, hab. session 10.70.71.31.00.9-0.70.7-0.8-0.8-0.9-0.9-0.9-0.8-0.9-0.8-0.8-0.9-0.8-0.80.8-0.80.7-1.2
Time in novel zone, hab. session 10.30.30.6-0.8-0.60.6-0.30.50.50.50.50.50.40.50.50.40.50.50.5-0.40.4-0.40.3
Total zone transitions, hab. session 10.50.71.41.20.9-1.10.6-0.8-0.9-0.8-0.8-0.7-0.8-0.8-0.7-0.8-0.8-0.9-0.80.9-0.90.90.4
Total locomotion distance, hab. session 10.30.51.21.10.9-1.00.5-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.5-0.7-0.7-0.6-0.50.7-0.70.6-0.1
Locomotion velocity, hab. session 10.40.61.41.20.9-1.20.6-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.6-0.7-0.7-0.7-0.60.8-0.80.70.3
Time in familiar zone, hab. session 22.42.54.01.11.3-1.31.6-1.5-1.6-1.6-1.7-1.7-1.5-1.6-1.5-1.5-1.6-1.7-1.51.7-1.71.7-2.0
Time in novel zone, hab. session 24.04.05.0-2.2-2.12.2-1.91.92.02.02.02.22.02.01.91.92.02.02.0-2.02.0-2.01.8
Total zone transitions, hab. session 20.81.02.31.51.1-1.50.9-1.0-1.0-0.8-0.8-0.9-1.0-0.8-0.9-0.9-0.8-1.1-1.00.9-0.91.00.6
Total locomotion distance, hab. session 20.30.31.21.10.7-1.00.5-0.5-0.5-0.5-0.5-0.6-0.5-0.5-0.5-0.5-0.5-0.5-0.40.5-0.50.5-0.0
Locomotion velocity, hab. session 20.10.20.91.00.6-0.90.3-0.3-0.3-0.3-0.3-0.4-0.2-0.3-0.3-0.3-0.3-0.3-0.20.3-0.30.30.4
Novel to familiar place preference ratio0.60.71.7-1.3-1.11.1-0.70.70.70.60.61.00.70.60.90.80.50.50.7-0.60.6-0.61.1
Novelty place preference1.01.12.8-1.7-1.41.4-0.90.90.90.70.81.30.90.71.11.00.70.71.0-0.80.8-0.81.3
Time in novel zone, NPP test0.80.82.6-1.6-1.31.3-0.80.80.80.60.71.10.80.61.00.80.60.60.9-0.70.7-0.71.0
Total zone transitions, NPP test0.60.92.31.51.2-1.41.0-0.9-1.0-0.8-0.8-0.9-0.8-0.8-0.9-0.8-0.7-0.9-0.90.9-0.90.90.1
Total locomotion distance, NPP test0.10.10.70.80.6-0.70.2-0.1-0.1-0.1-0.1-0.3-0.0-0.1-0.1-0.1-0.0-0.00.00.1-0.10.10.2
Locomotion velocity, NPP test0.00.10.50.70.5-0.60.10.10.00.10.1-0.20.10.10.10.10.10.10.2-0.00.0-0.10.3
Intraocular pressure1.31.92.6-0.7-1.31.1-1.31.51.41.61.61.21.61.51.41.61.61.41.5-1.41.4-1.40.2
Delta distance traveled before/after self-admin0.10.11.50.1-0.30.4-0.10.0-0.0-0.1-0.20.40.2-0.00.00.1-0.1-0.20.10.0-0.00.01.2
Delta ambulatory time before/after self-admin0.10.22.0-0.4-0.50.6-0.1-0.10.0-0.2-0.20.60.1-0.1-0.0-0.0-0.2-0.1-0.0-0.00.0-0.01.4
Parametrial fat weight5.212.317.24.14.2-4.13.8-3.4-3.5-3.3-3.2-3.7-3.4-3.3-3.6-3.4-3.2-3.3-3.43.5-3.53.5-2.5
Pavlov. Cond. lever latency0.60.71.00.60.6-0.50.8-0.9-0.9-0.9-0.9-0.8-0.9-0.9-0.7-0.9-0.9-1.0-0.90.8-0.80.9-1.0
Pavlov. Cond. magazine entry latency2.22.83.8-1.3-1.61.4-1.71.81.71.91.91.41.81.91.81.81.91.71.8-1.71.7-1.60.6
Pavlov. Cond. change in total contacts1.41.52.0-1.2-1.21.0-1.41.41.31.31.21.31.31.21.21.31.31.21.3-1.11.1-1.11.4
Pavlov. Cond. index score2.12.63.3-1.2-1.51.1-1.71.71.71.81.81.51.71.81.61.71.81.71.7-1.61.6-1.61.4
Pavlov. Cond. latency score1.72.22.7-1.1-1.31.0-1.51.51.51.61.61.41.61.61.51.61.71.61.6-1.51.5-1.51.2
Pavlov. Cond. lever contacts1.51.82.1-1.1-1.21.0-1.41.41.41.41.41.41.41.41.31.41.41.41.4-1.31.3-1.41.4
Pavlov. Cond. magazine entry number2.02.53.31.31.5-1.41.6-1.7-1.6-1.8-1.8-1.4-1.7-1.8-1.7-1.7-1.8-1.7-1.71.6-1.61.5-0.6
Pavlov. Cond. intertrial magazine entries0.40.54.60.50.5-0.30.3-0.5-0.6-0.6-0.6-0.9-0.5-0.6-0.5-0.6-0.7-0.5-0.50.5-0.50.5-2.1
Pavlov. Cond. lever-magazine prob. diff.2.22.73.2-1.3-1.51.1-1.71.71.71.81.81.61.71.81.71.71.81.71.7-1.61.6-1.61.5
Pavlov. Cond. response bias1.41.72.2-1.0-1.21.0-1.41.41.41.51.51.21.41.51.31.41.51.41.4-1.31.3-1.31.0
Pavlov. Cond. lever latency2.43.33.81.61.6-1.61.7-1.8-1.9-1.9-1.9-1.8-1.8-1.9-1.8-1.9-1.9-1.9-1.81.9-1.91.9-1.3
Pavlov. Cond. magazine entry latency4.25.15.8-2.3-2.42.3-2.32.42.32.42.32.12.32.42.42.42.42.22.3-2.12.1-2.21.0
Pavlov. Cond. change in total contacts3.96.27.4-2.1-2.22.1-2.72.62.62.72.72.32.62.72.62.72.72.62.6-2.72.7-2.61.1
Pavlov. Cond. index score4.86.57.4-2.5-2.52.4-2.62.62.62.72.62.52.62.72.62.72.72.62.6-2.52.5-2.61.6
Pavlov. Cond. latency score4.66.26.9-2.4-2.52.4-2.52.62.52.62.62.52.52.62.62.62.62.52.5-2.42.4-2.41.8
Pavlov. Cond. lever contacts3.34.65.3-1.9-1.91.9-2.12.22.22.32.32.12.22.32.22.32.32.32.2-2.32.3-2.31.5
Pavlov. Cond. magazine entry number6.17.68.62.92.9-2.82.9-2.8-2.8-2.9-2.8-2.6-2.8-2.9-2.9-2.9-2.8-2.7-2.82.6-2.62.7-1.2
Pavlov. Cond. intertrial magazine entries2.74.16.82.62.4-2.32.1-1.9-2.0-1.9-1.9-2.3-1.9-1.9-1.9-1.9-1.8-1.8-1.91.8-1.81.8-2.1
Pavlov. Cond. lever-magazine prob. diff.5.06.67.5-2.6-2.62.5-2.62.72.62.72.72.52.62.72.72.72.72.62.6-2.52.5-2.61.4
Pavlov. Cond. response bias5.06.87.9-2.5-2.52.5-2.62.62.72.82.82.52.62.82.72.82.82.72.6-2.72.7-2.71.3
Time in closed arm before self-admin2.12.76.62.62.1-2.11.7-1.5-1.7-1.5-1.6-1.4-1.4-1.4-1.6-1.4-1.4-1.5-1.61.6-1.61.60.4
Time in closed arm after self-admin2.72.84.41.61.8-2.11.7-1.4-1.8-1.8-1.9-1.6-1.7-1.7-1.7-1.8-1.7-1.8-1.41.8-1.81.80.3
Time in open arm before self-admin3.84.15.2-2.3-1.91.9-2.01.92.22.12.21.72.02.12.12.02.12.22.0-2.22.2-2.20.2
Time in open arm after self-admin1.01.11.7-1.0-0.71.2-0.90.61.21.21.30.71.11.11.01.21.11.30.7-1.21.2-1.2-1.1
Bone: periosteal estimation0.10.22.70.60.3-0.40.0-0.0-0.20.00.0-0.5-0.00.0-0.00.00.1-0.1-0.2-0.00.00.0-1.6
Bone: periosteal perimeter0.10.32.10.90.6-0.70.2-0.2-0.3-0.2-0.2-0.7-0.2-0.2-0.3-0.2-0.1-0.2-0.40.2-0.20.2-1.5
Bone: post-yield work1.01.52.00.91.1-1.11.1-1.3-1.3-1.3-1.3-1.2-1.3-1.3-1.3-1.3-1.3-1.4-1.41.1-1.11.3-0.9
Progressive ratio test 1 active lever presses1.72.14.6-1.8-2.11.9-1.61.41.41.41.41.51.31.41.51.41.31.21.4-1.11.1-1.10.6
Progressive ratio test 1 breakpoint1.51.84.1-1.7-2.01.8-1.61.31.31.31.31.41.31.31.41.31.21.11.4-1.11.1-1.10.6
Progressive ratio test 1 inactive lever presses0.20.30.70.10.0-0.10.3-0.5-0.6-0.6-0.7-0.2-0.6-0.6-0.5-0.6-0.7-0.8-0.40.8-0.80.80.3
Progressive ratio test 2 active lever presses0.40.41.7-1.3-1.31.3-0.70.30.50.40.30.90.20.40.50.30.30.30.4-0.30.3-0.20.9
Progressive ratio test 2 breakpoint0.40.51.8-1.3-1.31.3-0.80.40.50.40.41.00.30.40.50.40.40.40.4-0.30.3-0.31.0
Progressive ratio test 2 inactive lever presses0.20.30.60.10.0-0.00.4-0.8-0.7-0.6-0.7-0.4-0.8-0.6-0.6-0.6-0.6-0.8-0.70.6-0.60.8-0.5
Incentive Sensitization - Responses0.10.11.1-0.7-0.50.6-0.1-0.2-0.0-0.1-0.20.4-0.2-0.1-0.1-0.2-0.2-0.1-0.10.1-0.10.21.1
Incentive Sensitization - Breakpoint0.10.21.3-0.8-0.60.7-0.2-0.10.0-0.1-0.20.5-0.2-0.1-0.0-0.2-0.1-0.1-0.10.1-0.10.21.2
Sum of active levers in priming session hrs 5-60.10.10.3-0.4-0.50.5-0.30.40.40.20.20.30.20.30.30.20.20.30.3-0.40.4-0.4-0.2
Progressive ratio1.01.62.3-0.8-0.90.4-1.21.41.41.41.40.81.41.41.41.31.51.51.4-1.51.5-1.50.3
Food seeking constrained by brief footshock2.93.64.7-1.7-1.41.6-1.81.72.01.81.72.11.91.91.81.81.92.11.9-2.22.2-2.12.0
Seeking ratio, punishment vs. effort0.10.11.2-0.5-0.20.6-0.20.10.30.10.10.70.20.10.00.10.10.20.1-0.20.2-0.21.1
Retroperitoneal fat weight5.422.930.05.55.3-5.34.9-4.5-4.8-4.6-4.6-5.3-4.6-4.6-4.5-4.8-4.5-4.6-4.64.7-4.74.6-4.6
Reaction time number correct0.51.12.0-1.3-1.41.4-1.01.11.01.01.01.11.01.00.81.01.01.00.8-0.90.9-0.90.7
Reaction time mean minus median1.12.63.4-1.4-1.71.3-1.81.81.71.81.91.51.81.71.81.71.71.71.6-1.51.5-1.50.6
Reaction time mean minus median AUC1.12.93.8-1.3-1.71.3-1.81.91.81.91.91.51.91.91.91.81.81.91.6-1.61.6-1.60.6
Reaction time num false alarms0.10.10.5-0.1-0.10.10.2-0.4-0.0-0.2-0.20.3-0.4-0.3-0.2-0.3-0.4-0.1-0.30.0-0.00.10.7
Reaction time num false alarms AUC0.10.20.50.30.3-0.20.5-0.7-0.4-0.5-0.5-0.1-0.7-0.6-0.5-0.6-0.6-0.4-0.60.3-0.30.40.5
Reaction time trials correct on left0.51.12.0-1.3-1.41.4-1.01.11.01.01.01.11.01.00.81.01.01.00.8-0.90.9-0.90.7
Reaction time trials on left0.61.22.1-1.3-1.41.5-1.11.11.11.01.01.21.11.10.81.01.01.00.9-0.90.9-0.90.7
Reaction time mean0.40.61.2-0.4-0.40.3-0.70.90.91.01.10.60.90.90.90.80.91.00.7-0.90.9-0.80.1
Reaction time mean AUC0.50.71.3-0.5-0.60.5-0.80.90.91.01.10.81.00.91.00.91.01.00.7-0.90.9-0.90.4
Median of all reaction times0.10.10.40.10.1-0.2-0.20.40.40.50.60.20.40.40.40.40.40.50.2-0.50.5-0.4-0.1
Reaction time omissions0.20.30.8-0.3-0.50.1-0.70.50.50.70.70.40.60.60.90.50.70.50.5-0.40.4-0.4-0.0
Reaction time false alarm rate0.60.91.50.91.0-0.91.0-1.2-0.9-1.0-1.0-0.7-1.2-1.1-1.0-1.1-1.1-0.9-1.00.7-0.70.8-0.0
Reaction time premature initiation rate2.12.84.3-1.4-1.51.5-1.82.11.71.71.61.62.01.71.91.81.81.71.9-1.71.7-1.70.8
Reaction time premature initiations2.74.86.7-2.0-2.22.3-2.32.62.22.22.12.12.52.32.22.32.32.22.3-2.12.1-2.11.2
Std. dev. reaction times0.51.01.5-0.7-0.80.6-1.01.11.11.21.20.91.11.11.01.01.11.20.8-1.01.0-1.00.2
Reaction time trials completed0.61.22.1-1.3-1.41.5-1.11.11.11.01.01.21.11.10.81.01.01.00.9-0.90.9-0.90.7
Reaction time trials AUC0.61.22.2-1.4-1.51.5-1.11.21.11.11.11.21.11.10.91.11.11.10.9-0.90.9-1.00.6
Run reversals in cocaine runway, females1.41.43.41.81.7-1.21.3-1.1-1.2-1.0-1.0-1.3-1.1-1.0-1.2-1.2-1.0-0.9-0.91.0-1.00.9-1.3
Run reversals in cocaine runway, males0.10.10.60.80.6-0.40.2-0.1-0.2-0.2-0.2-0.2-0.2-0.2-0.1-0.2-0.2-0.2-0.00.2-0.20.2-0.2
Latency to leave start box in cocaine runway0.00.00.30.50.00.20.00.20.00.10.10.20.00.1-0.00.10.20.00.10.0-0.0-0.00.3
Latency to leave start box in cocaine runway, F0.10.10.4-0.2-0.30.60.1-0.1-0.2-0.3-0.40.2-0.3-0.3-0.3-0.3-0.4-0.4-0.20.5-0.50.40.4
Latency to leave start box in cocaine runway, M0.20.22.21.50.6-0.70.30.30.00.30.3-0.20.30.30.00.30.40.30.2-0.30.3-0.3-0.3
Std. dev. time between licks in bursts0.60.81.71.21.3-1.20.8-0.9-0.8-0.7-0.7-1.1-0.7-0.7-0.8-0.7-0.7-0.6-0.70.6-0.60.6-1.3
Total sessions with >9 infusions0.50.71.8-1.2-1.31.3-1.00.70.70.80.70.70.70.70.80.70.70.60.7-0.50.5-0.5-0.5
Short access day 1 total inactive lever presses0.40.51.70.30.3-0.30.5-0.6-0.7-0.7-0.7-0.7-0.6-0.7-0.5-0.6-0.7-0.8-0.60.8-0.80.8-1.3
Short access day 10 total inactive lever presses0.20.40.50.60.6-0.70.6-0.7-0.7-0.6-0.6-0.6-0.7-0.6-0.6-0.6-0.6-0.7-0.60.7-0.70.60.1
Short access day 1 total infusions0.10.10.2-0.3-0.40.40.0-0.3-0.2-0.4-0.4-0.0-0.2-0.4-0.2-0.4-0.5-0.4-0.20.4-0.40.4-0.4
Short access day 10 total infusions0.20.20.5-0.1-0.50.30.1-0.5-0.4-0.4-0.5-0.1-0.5-0.5-0.3-0.5-0.5-0.6-0.40.7-0.70.60.0
Short access total infusions0.40.52.1-1.2-1.51.3-0.80.40.50.50.50.80.50.50.60.40.40.30.5-0.20.2-0.20.2
Short access day 1 locomotion0.10.10.4-0.6-0.40.5-0.40.30.30.20.20.30.30.20.30.30.20.20.1-0.30.3-0.30.1
Short access day 10 total locomotion3.15.77.12.21.9-2.02.3-2.5-2.5-2.3-2.4-2.6-2.3-2.4-2.3-2.2-2.4-2.5-2.72.6-2.62.4-2.4
Short access total locomotion1.51.82.81.00.8-0.91.1-1.4-1.4-1.2-1.3-1.4-1.3-1.3-1.2-1.1-1.3-1.5-1.71.6-1.61.5-1.5
One hour access (0.3 mA shock)0.20.21.0-0.8-1.00.8-0.50.20.20.20.20.60.10.20.30.20.10.10.3-0.10.10.00.9
Compulsive drug intake0.10.10.30.10.2-0.1-0.20.50.30.20.30.10.50.30.30.30.30.40.3-0.60.6-0.4-0.4
One hour access (shock baseline)0.10.20.9-0.7-0.80.7-0.1-0.4-0.2-0.2-0.20.3-0.5-0.3-0.2-0.4-0.4-0.4-0.10.6-0.60.50.9
Social response proportion0.10.10.5-0.7-0.70.6-0.2-0.00.1-0.2-0.20.30.1-0.20.1-0.1-0.2-0.1-0.0-0.10.1-0.00.1
Social responses0.00.00.2-0.3-0.20.10.00.00.0-0.0-0.1-0.00.0-0.0-0.00.0-0.0-0.1-0.1-0.00.0-0.0-0.5
Social time0.10.11.20.1-0.10.10.3-0.3-0.2-0.4-0.3-0.3-0.2-0.4-0.4-0.4-0.5-0.3-0.30.1-0.10.2-1.1
Soleus weight0.00.10.60.50.6-0.60.4-0.1-0.3-0.2-0.2-0.5-0.1-0.2-0.1-0.1-0.1-0.2-0.20.3-0.30.3-0.8
Bone: stiffness4.57.38.2-2.7-2.82.5-2.92.82.72.82.82.62.82.82.82.82.82.62.7-2.82.8-2.71.6
Tibialis anterior weight1.03.33.9-1.2-1.71.4-1.91.91.91.92.01.81.91.91.91.91.92.01.9-1.91.9-1.91.5
Time to tail flick, vehicle, before self-admin0.10.10.6-0.8-0.60.6-0.50.30.30.30.20.50.30.20.30.40.20.10.2-0.20.2-0.20.3
Time to tail flick, vehicle, after self-admin2.02.63.41.21.1-1.31.5-1.6-1.7-1.6-1.8-1.5-1.8-1.7-1.6-1.7-1.7-1.8-1.61.9-1.91.9-1.3
Time to tail flick, test, before self-admin2.22.33.41.71.5-1.81.5-1.6-1.5-1.5-1.6-1.4-1.4-1.5-1.5-1.4-1.5-1.5-1.61.6-1.61.6-0.1
Time to tail flick, test, after self-admin0.20.20.70.5-0.1-0.30.2-0.2-0.5-0.3-0.4-0.5-0.2-0.3-0.3-0.3-0.3-0.6-0.10.8-0.80.8-0.7
Delta time to tail flick, vehicle, before/after SA1.51.53.51.50.8-0.91.1-1.1-1.2-1.1-1.2-1.3-1.3-1.1-1.2-1.2-1.1-1.2-1.01.2-1.21.2-1.9
Delta time to tail flick, test, before/after SA1.31.31.9-1.2-1.31.2-1.31.31.01.31.20.91.21.31.21.11.31.01.4-0.90.9-0.9-0.3
Tibia length0.10.40.6-0.1-0.40.3-0.50.70.60.70.80.60.70.70.70.70.70.60.6-0.70.7-0.50.6
Ambulatory time before self-admin0.20.32.90.10.8-0.8-0.10.50.20.50.4-0.60.30.50.30.40.60.30.4-0.20.2-0.2-1.7
Ambulatory time after self-admin0.00.10.3-0.50.5-0.50.00.1-0.10.0-0.1-0.30.10.00.10.10.1-0.10.10.1-0.10.1-0.4
Bone: tissue strength0.70.71.4-0.00.3-0.20.6-0.9-0.9-0.9-0.9-0.5-0.9-0.9-0.8-0.9-0.9-1.0-0.81.2-1.21.2-0.2
Total heroin consumption0.30.30.8-0.9-0.80.9-0.60.50.50.30.40.70.40.40.50.40.40.40.4-0.40.4-0.40.7
Bone: trabecular number0.20.30.70.80.7-0.80.4-0.6-0.6-0.6-0.6-0.5-0.7-0.6-0.6-0.6-0.6-0.6-0.60.3-0.30.3-0.2
Bone: trabecular spacing0.00.10.20.30.2-0.20.4-0.1-0.2-0.1-0.1-0.2-0.1-0.1-0.3-0.1-0.1-0.1-0.20.3-0.30.2-0.5
Bone: trabecular thickness0.70.91.2-0.9-0.90.9-1.00.91.11.01.00.90.91.01.11.01.01.11.0-1.01.0-1.00.4
Bone: trabecular tissue density0.40.61.7-1.0-0.90.8-0.90.80.80.80.81.00.80.70.80.70.70.70.7-0.60.6-0.51.3
Water consumed over 24 hours0.00.10.40.40.3-0.5-0.1-0.1-0.1-0.1-0.1-0.1-0.0-0.0-0.2-0.0-0.0-0.1-0.20.2-0.20.20.7
Number of responses in last shaping day1.82.02.8-1.0-1.01.1-1.41.71.51.51.41.31.51.51.51.61.51.51.5-1.71.7-1.60.6