Hub : Genes

Lbhd2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL intron excision ratio chr6_130442458_130444051 0.08 0.07 1.7e-07 0.05 0.06 0.05 0.05 2.5e-06 5.3e-07 3.7e-06 2.7e-06
2 Brain intron excision ratio chr6_130442448_130444051 0.28 0.17 0.0e+00 0.22 0.24 0.23 0.23 6.4e-20 8.1e-22 3.4e-21 3.5e-21
3 PL intron excision ratio chr6_130442448_130444051 0.13 0.08 1.7e-16 0.14 0.14 0.14 0.14 2.7e-15 1.4e-15 2.9e-15 2.8e-15
4 pVTA gene expression Lbhd2 0.07 0.07 5.2e-03 0.03 0.03 0.03 0.03 1.8e-02 1.4e-02 2.2e-02 2.9e-02
5 BLA intron excision ratio chr6_130442448_130444051 0.1 0.07 1.0e-06 0.1 0.12 0.11 0.11 3.9e-06 3.8e-07 2.2e-06 1.3e-06
6 Brain gene expression Lbhd2 0.05 0.04 6.3e-04 0.03 0.03 0.02 0.03 1.2e-03 9.7e-04 2.3e-03 1.1e-03
7 NAcc gene expression Lbhd2 0.02 0.02 5.2e-03 0.01 0.02 0.01 0.01 1.0e-02 3.8e-03 1.2e-02 8.1e-03
8 pVTA intron excision ratio chr6_130442458_130444051 0.2 0.22 2.5e-05 0.1 0.1 0.1 0.08 6.5e-05 4.0e-05 5.8e-05 2.4e-04
9 pVTA intron excision ratio chr6_130442448_130444051 0.65 0.19 5.7e-10 0.18 0.18 0.16 0.17 3.6e-08 3.3e-08 1.2e-07 1.1e-07
10 PL intron excision ratio chr6_130442448_130444056 0.03 0.03 3.3e-03 0.02 0.01 0.02 0.02 1.4e-03 7.2e-03 4.9e-03 2.8e-03
11 RMTg intron excision ratio chr6_130442448_130444051 0.13 0.11 5.6e-03 0.06 0.05 0.01 0.05 8.0e-03 1.8e-02 1.4e-01 2.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.10.20.9-0.10.20.2-0.20.3-0.2-0.2-0.2-0.10.9-0.9
Area under the delay curve0.20.20.4-0.60.30.5-0.30.2-0.4-0.4-0.30.6-0.50.5
BMI with tail2.37.412.1-3.32.93.0-2.82.6-2.9-2.9-2.93.50.5-0.5
BMI without tail0.71.43.4-1.51.21.1-1.00.9-1.0-1.0-1.11.8-1.11.1
Body weight0.20.82.90.3-0.6-0.50.6-0.80.60.50.6-0.0-1.71.7
Weight adjusted by age0.00.00.00.0-0.1-0.10.1-0.20.10.10.1-0.1-0.20.2
Bone surface0.00.00.0-0.10.20.1-0.10.2-0.1-0.1-0.10.00.2-0.2
Bone volume0.10.10.4-0.00.20.1-0.20.3-0.1-0.1-0.2-0.00.6-0.6
Breakpoint value in progressive ratio session0.00.00.10.00.0-0.0-0.00.1-0.0-0.0-0.0-0.10.3-0.3
Number of licking bursts0.30.41.60.1-0.2-0.30.3-0.40.40.30.30.2-1.31.3
Context. condit. distance diff. score1.62.02.91.6-1.5-1.51.5-1.41.51.51.5-1.7-0.60.6
Locomotion velocity, session 10.30.40.40.6-0.5-0.70.6-0.50.70.60.6-0.5-0.70.7
Locomotion distance, session 10.30.30.6-0.60.80.5-0.60.6-0.5-0.6-0.70.70.3-0.3
Locomotion velocity, session 20.00.00.1-0.10.10.2-0.20.1-0.2-0.3-0.20.20.1-0.1
Locomotion distance, session 20.30.40.6-0.60.70.6-0.60.6-0.6-0.6-0.70.80.4-0.4
Locomotion velocity, session 30.50.52.3-0.20.40.5-0.50.5-0.5-0.5-0.4-0.01.5-1.5
Locomotion distance, session 30.20.20.80.4-0.2-0.20.2-0.10.20.20.2-0.60.9-0.9
Stereotopy head waving bouts, day 30.10.10.20.4-0.4-0.40.4-0.40.40.40.4-0.3-0.30.3
Stereotopy head waving duration, day 30.20.20.30.5-0.4-0.50.5-0.50.50.40.4-0.3-0.50.5
Locomotion velocity, session 70.91.04.1-0.20.50.6-0.60.7-0.7-0.6-0.6-0.12.0-2.0
Locomotion distance, session 71.11.43.7-0.71.01.0-1.01.1-1.0-1.0-1.00.51.9-1.9
Stereotopy head waving bouts, day 70.80.91.71.2-1.1-1.01.0-0.91.01.01.0-1.3-0.10.1
Stereotopy head waving duration, day 70.20.30.50.6-0.6-0.50.6-0.60.50.60.6-0.7-0.20.2
Locomotion velocity, session 80.10.20.30.5-0.4-0.40.4-0.40.40.40.4-0.5-0.00.0
Locomotion distance, session 80.10.10.50.10.2-0.0-0.10.2-0.0-0.1-0.1-0.10.7-0.7
Degree of sensitization distance0.10.10.2-0.40.40.4-0.40.4-0.4-0.4-0.40.30.3-0.3
Degree of sensitization stereotypy0.20.20.60.6-0.5-0.50.4-0.40.40.50.5-0.80.3-0.3
Conditioned locomotion1.11.32.31.3-1.3-1.11.2-1.11.11.21.2-1.50.1-0.1
Cocaine response after cond. corrected0.40.50.8-0.80.80.7-0.70.7-0.7-0.7-0.70.90.3-0.3
Cocaine response after cond. not corrected1.71.82.5-1.51.51.4-1.41.4-1.4-1.4-1.51.60.8-0.8
Cocaine response before conditioning2.42.93.2-1.71.71.8-1.81.7-1.8-1.8-1.71.61.5-1.5
Saline control response0.40.62.2-0.20.50.4-0.50.6-0.5-0.4-0.4-0.01.5-1.5
Bone: connectivity density0.00.00.10.3-0.2-0.20.2-0.20.20.20.2-0.30.1-0.1
Bone: cortical apparent density7.810.311.73.3-3.4-3.33.3-3.43.33.33.3-3.2-2.72.7
Bone: cortical area1.31.93.11.6-1.4-1.61.4-1.31.51.61.5-1.8-0.30.3
Bone: cortical porosity0.20.21.10.2-0.1-0.0-0.00.1-0.00.00.0-0.41.0-1.0
Bone: cortical porosity0.40.51.7-0.30.40.4-0.50.6-0.5-0.4-0.50.11.3-1.3
Bone: cortical thickness1.22.03.61.7-1.4-1.61.4-1.21.51.51.5-1.90.2-0.2
Bone: cortical thickness1.01.12.01.3-1.1-1.21.1-0.91.21.21.1-1.40.1-0.1
Bone: cortical tissue density8.010.611.73.3-3.4-3.33.4-3.43.33.33.3-3.2-2.92.9
Condit. Reinf. active minus inactive responses0.50.50.6-0.80.80.7-0.70.7-0.7-0.7-0.70.70.6-0.6
Condit. Reinf. active-inactive response ratio2.32.42.7-1.71.61.6-1.61.6-1.6-1.6-1.61.61.3-1.3
Condit. Reinf. active responses0.20.20.4-0.40.50.5-0.50.5-0.5-0.5-0.50.40.6-0.6
Condit. Reinf. inactive responses1.72.02.21.5-1.4-1.51.5-1.51.51.41.4-1.3-1.21.2
Incentive salience index mean0.40.50.6-0.70.70.7-0.70.7-0.7-0.7-0.70.70.7-0.7
Condit. Reinf. lever presses0.10.20.4-0.30.40.4-0.40.4-0.4-0.4-0.40.30.7-0.7
Condit. Reinf. active minus inactive responses0.40.51.10.5-0.5-0.60.6-0.70.60.60.6-0.3-1.11.1
Condit. Reinf. active-inactive response ratio0.40.40.60.6-0.6-0.60.7-0.70.60.60.6-0.5-0.80.8
Condit. Reinf. active responses0.10.10.2-0.20.20.2-0.10.0-0.1-0.2-0.20.4-0.50.5
Condit. Reinf. inactive responses0.60.70.8-0.90.90.9-0.90.9-0.9-0.9-0.90.90.6-0.6
Condit. Reinf. lever presses1.62.12.8-1.61.61.5-1.51.5-1.5-1.6-1.61.70.7-0.7
Condit. Reinf. lever reinforcers received0.10.10.2-0.20.20.2-0.10.1-0.2-0.2-0.20.4-0.40.4
Conditioned reinforcement - actives1.81.82.51.5-1.5-1.41.4-1.41.41.41.4-1.6-0.60.6
Conditioned reinforcement - inactives0.30.30.50.7-0.6-0.60.6-0.60.60.60.6-0.7-0.20.2
Conditioned locomotion0.91.02.1-0.70.90.9-1.01.0-1.0-0.9-0.90.61.5-1.5
Patch foraging indifference point 0 sec2.74.35.42.3-2.3-2.12.2-2.22.12.12.2-2.3-1.41.4
Patch foraging indifference point AUC2.63.04.11.6-1.6-1.71.7-1.81.71.71.7-1.4-2.02.0
Delay disc. indifference point, 0s delay0.10.10.20.1-0.2-0.20.2-0.30.20.20.2-0.1-0.40.4
Delay disc. indifference point, 16s delay0.10.10.3-0.40.20.3-0.20.1-0.3-0.3-0.20.5-0.60.6
Delay disc. indifference point, 2s delay0.10.10.2-0.30.30.2-0.20.2-0.2-0.2-0.20.4-0.30.3
Delay disc. indifference point, 24s delay0.10.10.4-0.40.20.2-0.10.1-0.1-0.1-0.10.4-0.70.7
Delay disc. indifference point, 4s delay0.20.21.10.0-0.3-0.10.3-0.40.20.20.30.1-1.01.0
Delay disc. indifference point, 8s delay0.30.30.6-0.80.50.7-0.50.4-0.6-0.6-0.50.8-0.30.3
Indifference point function ln k0.40.61.00.9-0.9-0.90.8-0.80.80.90.9-1.0-0.10.1
Indifference point function log k0.40.61.00.9-0.9-0.90.8-0.80.80.90.9-1.0-0.10.1
Patch foraging total patch changes 0 sec2.94.75.92.3-2.4-2.22.3-2.32.22.22.3-2.3-1.51.5
Patch foraging total patch changes 12 sec3.14.04.52.0-2.1-1.92.0-2.12.01.92.0-1.8-2.02.0
Patch foraging total patch changes 18 sec1.01.31.81.3-1.3-1.11.2-1.31.11.11.2-1.3-0.70.7
Patch foraging total patch changes 24 sec0.20.31.10.2-0.4-0.20.3-0.50.30.30.3-0.1-1.01.0
Patch foraging total patch changes 6 sec1.92.85.51.4-1.6-1.51.6-1.81.51.51.6-1.1-2.32.3
Patch foraging time to switch 0 sec10.416.017.3-4.14.14.2-4.14.1-4.1-4.1-4.13.83.6-3.6
Patch foraging water rate 0 sec17.427.930.15.4-5.5-5.45.5-5.55.45.45.4-5.1-4.74.7
Patch foraging water rate 12 sec9.414.419.03.5-3.7-3.83.8-3.93.83.73.7-3.0-4.44.4
Patch foraging water rate 18 sec4.86.47.22.6-2.7-2.72.6-2.62.72.72.6-2.6-2.02.0
Patch foraging water rate 24 sec4.15.76.12.3-2.4-2.52.4-2.42.52.52.4-2.2-2.32.3
Patch foraging water rate 6 sec4.26.26.92.6-2.6-2.62.6-2.62.62.62.6-2.5-2.02.0
Seeking ratio, delayed vs. immediate footshock0.30.40.90.5-0.5-0.60.6-0.60.60.60.6-0.4-0.90.9
Distance traveled before self-admin0.10.10.2-0.30.20.2-0.20.1-0.1-0.2-0.20.4-0.50.5
Distance traveled after self-admin0.50.50.60.7-0.7-0.80.7-0.70.80.70.7-0.6-0.80.8
Extensor digitorum longus weight5.722.523.94.6-4.7-4.94.8-4.94.94.84.8-4.2-4.84.8
Bone: elastic displacement0.60.71.21.0-0.9-1.00.9-0.80.90.90.9-1.1-0.10.1
Bone: elastic work0.20.20.40.6-0.4-0.60.5-0.40.60.60.5-0.70.1-0.1
Bone: endosteal estimation0.20.40.7-0.80.70.6-0.60.5-0.6-0.6-0.60.9-0.40.4
Bone: endosteal perimeter0.00.10.5-0.10.1-0.10.1-0.10.10.10.10.2-0.70.7
Epididymis fat weight4.39.911.0-3.33.23.3-3.33.3-3.3-3.3-3.23.12.7-2.7
Delta time in closed arm before/after self-admin0.00.00.1-0.20.20.2-0.20.2-0.2-0.2-0.20.20.2-0.2
Delta time in open arm before/after self-admin0.60.51.20.5-0.7-0.60.7-0.80.60.60.7-0.4-1.11.1
Diff in mean of infusions in LGA sessions0.10.10.40.3-0.2-0.20.1-0.10.10.20.2-0.40.6-0.6
Delay discount exponential model param0.20.20.40.5-0.3-0.40.2-0.10.30.30.3-0.50.6-0.6
Extinction: sum of active levers before priming0.00.00.10.10.10.0-0.10.1-0.0-0.0-0.1-0.00.2-0.2
Active lever presses in extinction session 61.21.21.31.1-1.1-1.21.1-1.11.11.11.1-1.1-1.01.0
Bone: final force0.50.71.61.0-0.8-1.00.8-0.70.90.90.9-1.30.3-0.3
Bone: final moment0.50.91.71.1-0.9-1.10.9-0.71.01.01.0-1.30.2-0.2
Food consumed during 24 hour testing period0.10.20.30.3-0.3-0.40.4-0.40.40.40.4-0.3-0.50.5
Glucose0.71.11.81.2-1.2-1.11.1-1.11.11.11.2-1.3-0.20.2
Heart weight0.00.00.0-0.10.10.1-0.10.1-0.2-0.2-0.10.20.0-0.0
Delay discount hyperbolic model param0.20.20.30.5-0.3-0.40.3-0.20.40.30.3-0.60.6-0.6
Intermittent access intake day 1-15 change1.41.42.2-1.01.11.1-1.21.2-1.1-1.2-1.20.91.5-1.5
Intermittent access intake escalation1.61.62.4-1.01.21.2-1.31.3-1.2-1.2-1.31.01.5-1.5
Intermittent access intake escalation 20.10.10.4-0.20.30.2-0.30.4-0.3-0.3-0.30.10.7-0.7
Intermitt. access day 1 inactive lever presses2.42.63.01.7-1.7-1.71.7-1.61.71.71.7-1.7-1.21.2
Intermitt. access day 15 inactive lever presses0.70.81.11.0-1.0-0.90.9-0.90.90.91.0-1.1-0.40.4
Intermitt. access escalation Index0.70.62.50.2-0.5-0.40.5-0.70.50.50.5-0.0-1.61.6
Intermittent access day 1 total infusions0.40.40.6-0.80.70.7-0.70.6-0.7-0.7-0.70.80.3-0.3
Intermittent access day 15 total infusions1.82.02.2-1.41.51.5-1.51.5-1.5-1.5-1.51.41.2-1.2
Intermittent access terminal intake (last 3 days)2.12.32.5-1.51.61.6-1.61.6-1.6-1.6-1.61.61.2-1.2
Intermittent access total infusions0.80.91.0-0.91.01.0-1.00.9-1.0-1.0-1.00.90.7-0.7
Intermittent access day 1 locomotion1.01.01.1-1.01.01.1-1.01.0-1.1-1.0-1.01.00.9-0.9
Intermittent access day 15 total locomotion0.40.40.5-0.50.60.6-0.60.7-0.6-0.6-0.60.50.7-0.7
Intermittent access total locomotion0.50.60.7-0.60.70.7-0.80.8-0.7-0.8-0.80.60.8-0.8
Intermittent access standard deviation3.53.74.0-1.82.01.9-2.02.0-1.9-1.9-2.01.71.9-1.9
Left kidney weight0.51.41.71.1-1.3-1.11.2-1.31.21.21.2-1.1-1.11.1
Right kidney weight0.20.60.80.7-0.9-0.70.8-0.90.70.80.8-0.6-0.80.8
Cocaine induced anxiety2.93.43.51.8-1.8-1.91.9-1.91.91.91.9-1.7-1.81.8
Post-drug Anxiety2.42.72.91.6-1.7-1.71.7-1.71.71.71.7-1.5-1.61.6
Baseline Anxiety1.51.61.7-1.31.21.3-1.31.3-1.3-1.3-1.31.11.3-1.3
Tail length3.19.39.93.0-3.0-3.13.1-3.13.13.13.0-2.6-3.13.1
Length with tail3.813.715.53.9-3.9-3.93.9-3.93.93.83.8-3.8-2.92.9
Length without tail1.53.24.82.1-2.0-1.81.9-1.91.81.81.9-2.2-0.70.7
Times rat made contact with spout0.30.30.60.6-0.7-0.50.6-0.60.50.60.6-0.8-0.00.0
Lifetime Intake0.40.50.5-0.60.70.7-0.70.7-0.7-0.7-0.70.60.7-0.7
Liver weight, left3.65.88.62.1-2.2-2.42.4-2.42.42.42.3-1.8-2.92.9
Liver weight, right0.00.00.0-0.1-0.1-0.00.1-0.10.00.00.10.1-0.20.2
Locomotor activity0.10.10.20.4-0.4-0.20.3-0.20.20.30.3-0.50.3-0.3
Locomotor testing distance0.20.40.90.8-0.7-0.60.6-0.50.60.60.6-1.00.4-0.4
Locomotor testing rearing1.72.64.4-1.31.41.6-1.61.6-1.6-1.6-1.51.12.1-2.1
Locomotion in novel chamber5.46.68.62.3-2.5-2.62.6-2.62.62.52.5-2.1-2.92.9
Locomotion in novel chamber post-restriction0.10.10.4-0.40.30.1-0.20.1-0.1-0.1-0.20.5-0.60.6
Fecal boli incidents, locomotor time 11.41.52.8-1.51.41.2-1.31.2-1.2-1.2-1.31.70.0-0.0
Change in fecal boli incidents, locomotor task0.10.10.30.3-0.4-0.30.3-0.40.30.30.3-0.3-0.50.5
Time >=10cm from walls, locomotor time 10.40.40.6-0.80.70.7-0.70.7-0.7-0.7-0.70.70.4-0.4
Bouts of movement, locomotor time 10.91.01.3-1.01.11.0-1.01.1-1.0-1.0-1.01.00.8-0.8
Total resting periods, locomotor time 11.01.11.3-1.11.11.0-1.11.1-1.0-1.0-1.11.00.9-0.9
Rest time, locomotor task time 10.40.51.50.3-0.5-0.50.5-0.60.50.50.5-0.2-1.21.2
Distance moved, locomotor task time 10.70.72.3-0.40.60.7-0.70.8-0.7-0.7-0.70.31.5-1.5
Vertical activity count, locomotor time 10.50.51.00.9-0.8-0.80.7-0.70.70.70.7-1.00.2-0.2
Time >=10cm from walls, locomotor time 20.60.61.20.9-0.8-0.80.8-0.70.80.80.8-1.10.2-0.2
Bouts of movement, locomotor time 22.32.43.01.4-1.4-1.61.6-1.61.61.61.6-1.3-1.71.7
Total resting periods, locomotor time 21.81.93.01.1-1.3-1.41.4-1.41.41.41.3-1.0-1.71.7
Rest time, locomotor task time 20.60.71.80.4-0.7-0.70.7-0.70.70.70.7-0.4-1.31.3
Distance moved, locomotor task time 20.70.93.4-0.20.50.6-0.60.7-0.6-0.6-0.60.11.8-1.8
Vertical activity count, locomotor time 20.60.61.41.1-0.7-0.80.7-0.60.70.70.7-1.20.7-0.7
Light reinforcement 10.00.00.1-0.20.10.2-0.20.2-0.2-0.2-0.20.10.3-0.3
Light reinforcement 21.31.72.3-1.21.31.2-1.31.4-1.2-1.2-1.31.01.5-1.5
Bone: marrow area0.10.30.6-0.70.60.5-0.50.5-0.5-0.5-0.50.8-0.40.4
Bone: maximum diameter0.20.30.80.3-0.3-0.50.4-0.40.50.50.4-0.2-0.90.9
Bone: maximum force0.50.81.71.1-0.9-1.00.8-0.70.91.00.9-1.30.3-0.3
Bone: maximum moment0.40.71.61.0-0.8-1.00.8-0.70.91.00.9-1.30.3-0.3
Mean time between licks in bursts0.91.21.4-1.11.21.1-1.21.2-1.1-1.1-1.21.11.0-1.0
Mean num. licks in bursts0.30.41.70.3-0.10.0-0.00.1-0.10.00.1-0.61.3-1.3
Cd content in liver0.80.93.20.5-0.5-0.80.7-0.70.80.70.6-0.1-1.81.8
Co content in liver0.70.81.01.0-0.9-1.00.9-0.91.00.90.9-0.8-0.90.9
Cu content in liver0.91.01.6-1.21.11.1-1.11.0-1.1-1.1-1.11.30.4-0.4
Fe content in liver0.10.10.1-0.30.30.3-0.30.3-0.3-0.3-0.30.20.4-0.4
K content in liver0.10.10.10.3-0.3-0.20.3-0.30.20.20.3-0.3-0.20.2
Mg content in liver0.00.00.10.2-0.2-0.10.2-0.20.10.10.2-0.1-0.30.3
Mn content in liver0.30.31.40.3-0.10.00.00.1-0.00.00.1-0.61.2-1.2
Na content in liver0.00.00.0-0.10.10.1-0.10.1-0.1-0.1-0.10.10.2-0.2
Rb content in liver0.50.60.80.8-0.9-0.80.8-0.90.80.80.8-0.8-0.80.8
Se content in liver0.20.31.1-0.40.30.1-0.10.1-0.1-0.1-0.20.6-1.01.0
Sr content in liver0.50.51.10.5-0.5-0.70.6-0.60.70.70.6-0.3-1.11.1
Zn content in liver0.30.41.30.4-0.4-0.50.5-0.50.50.50.4-0.1-1.11.1
Bone: minimum diameter0.71.21.51.2-1.1-1.21.2-1.11.21.21.2-1.2-0.80.8
Time in familiar zone, hab. session 10.90.91.8-0.70.80.9-0.90.9-0.9-0.9-0.90.61.3-1.3
Time in novel zone, hab. session 10.20.20.7-0.30.20.0-0.10.1-0.0-0.0-0.10.4-0.90.9
Total zone transitions, hab. session 10.60.81.3-0.70.90.8-0.90.9-0.8-0.8-0.90.71.1-1.1
Total locomotion distance, hab. session 10.00.00.10.2-0.1-0.20.1-0.10.20.20.1-0.20.3-0.3
Locomotion velocity, hab. session 10.30.50.70.8-0.7-0.80.7-0.70.80.80.7-0.8-0.20.2
Time in familiar zone, hab. session 20.90.91.6-0.70.81.0-0.90.9-1.0-1.0-0.90.61.3-1.3
Time in novel zone, hab. session 20.20.21.2-0.20.1-0.10.0-0.00.10.0-0.00.4-1.11.1
Total zone transitions, hab. session 20.50.70.9-0.81.00.8-0.90.9-0.8-0.8-0.90.90.7-0.7
Total locomotion distance, hab. session 20.40.60.80.8-0.7-0.90.8-0.70.80.80.7-0.7-0.70.7
Locomotion velocity, hab. session 20.60.81.11.0-0.9-1.00.9-0.91.01.00.9-0.9-0.50.5
Novel to familiar place preference ratio0.20.20.3-0.50.50.5-0.50.5-0.5-0.5-0.50.50.2-0.2
Novelty place preference0.10.10.2-0.40.40.4-0.40.4-0.4-0.4-0.40.40.1-0.1
Time in novel zone, NPP test0.10.10.1-0.40.30.3-0.30.4-0.3-0.3-0.30.30.1-0.1
Total zone transitions, NPP test0.10.10.3-0.40.50.2-0.30.4-0.2-0.3-0.40.6-0.00.0
Total locomotion distance, NPP test0.10.10.10.3-0.2-0.40.3-0.20.30.30.3-0.30.0-0.0
Locomotion velocity, NPP test0.10.10.20.4-0.3-0.40.3-0.20.40.40.3-0.3-0.10.1
Intraocular pressure0.10.10.2-0.20.20.3-0.30.3-0.3-0.2-0.20.10.4-0.4
Delta distance traveled before/after self-admin0.10.20.50.4-0.2-0.20.1-0.00.20.20.2-0.50.7-0.7
Delta ambulatory time before/after self-admin0.50.61.11.0-0.8-0.80.8-0.70.80.80.8-1.00.1-0.1
Parametrial fat weight0.10.20.9-0.20.0-0.10.1-0.10.10.10.00.3-1.01.0
Pavlov. Cond. lever latency0.60.81.01.0-0.9-0.90.9-0.90.90.90.9-1.0-0.60.6
Pavlov. Cond. magazine entry latency0.70.92.3-0.60.70.8-0.80.9-0.8-0.8-0.80.41.5-1.5
Pavlov. Cond. change in total contacts0.30.40.4-0.60.60.6-0.60.6-0.6-0.7-0.60.60.6-0.6
Pavlov. Cond. index score0.91.11.2-1.11.11.1-1.11.1-1.1-1.1-1.11.01.0-1.0
Pavlov. Cond. latency score0.50.70.8-0.90.90.8-0.90.9-0.8-0.9-0.90.90.6-0.6
Pavlov. Cond. lever contacts0.81.01.1-1.11.01.0-1.01.0-1.0-1.0-1.01.00.8-0.8
Pavlov. Cond. magazine entry number1.11.41.61.1-1.2-1.21.2-1.21.21.21.2-1.0-1.31.3
Pavlov. Cond. intertrial magazine entries5.06.06.92.6-2.6-2.62.6-2.62.62.62.6-2.6-1.61.6
Pavlov. Cond. lever-magazine prob. diff.0.60.80.9-0.80.90.8-0.90.9-0.8-0.8-0.90.70.9-0.9
Pavlov. Cond. response bias1.41.72.9-1.11.21.2-1.21.3-1.2-1.2-1.20.91.7-1.7
Pavlov. Cond. lever latency2.12.83.41.7-1.8-1.71.8-1.81.71.71.8-1.8-1.21.2
Pavlov. Cond. magazine entry latency4.75.46.1-2.52.42.5-2.42.4-2.5-2.4-2.42.41.7-1.7
Pavlov. Cond. change in total contacts4.15.76.2-2.42.42.5-2.52.4-2.5-2.5-2.52.32.0-2.0
Pavlov. Cond. index score4.96.37.1-2.72.72.7-2.62.6-2.6-2.7-2.72.61.8-1.8
Pavlov. Cond. latency score4.86.06.7-2.62.62.6-2.62.5-2.6-2.6-2.62.61.8-1.8
Pavlov. Cond. lever contacts2.73.85.2-2.12.22.0-2.12.0-2.0-2.1-2.12.31.0-1.0
Pavlov. Cond. magazine entry number4.04.95.72.4-2.3-2.42.3-2.22.42.42.3-2.3-1.61.6
Pavlov. Cond. intertrial magazine entries4.55.87.82.7-2.7-2.52.6-2.52.52.52.6-2.8-1.21.2
Pavlov. Cond. lever-magazine prob. diff.5.67.17.9-2.82.82.8-2.82.8-2.8-2.8-2.82.72.0-2.0
Pavlov. Cond. response bias3.85.26.8-2.52.52.4-2.42.4-2.4-2.4-2.52.61.3-1.3
Time in closed arm before self-admin2.73.13.7-1.91.91.9-1.91.8-1.8-1.8-1.91.91.2-1.2
Time in closed arm after self-admin1.61.71.9-1.41.31.4-1.31.3-1.3-1.3-1.31.31.0-1.0
Time in open arm before self-admin4.75.15.62.3-2.3-2.32.3-2.42.32.32.3-2.1-2.12.1
Time in open arm after self-admin3.13.43.91.7-1.9-1.81.9-1.91.81.81.8-1.6-2.02.0
Bone: periosteal estimation0.20.40.60.5-0.5-0.70.6-0.50.70.70.6-0.5-0.80.8
Bone: periosteal perimeter0.10.20.30.4-0.3-0.50.4-0.40.50.50.4-0.4-0.50.5
Bone: post-yield work1.01.41.81.3-1.3-1.21.2-1.21.21.31.3-1.4-0.70.7
Progressive ratio test 1 active lever presses0.10.10.2-0.10.20.2-0.20.2-0.2-0.2-0.20.00.5-0.5
Progressive ratio test 1 breakpoint0.20.20.4-0.30.30.4-0.40.4-0.4-0.4-0.40.20.6-0.6
Progressive ratio test 1 inactive lever presses2.42.63.61.9-1.7-1.81.7-1.71.71.71.7-1.9-0.80.8
Progressive ratio test 2 active lever presses0.00.00.0-0.10.10.1-0.10.1-0.2-0.2-0.10.10.2-0.2
Progressive ratio test 2 breakpoint0.00.00.0-0.10.10.1-0.10.1-0.1-0.1-0.10.10.2-0.2
Progressive ratio test 2 inactive lever presses0.70.80.91.0-0.9-0.90.9-0.90.90.90.9-0.9-0.80.8
Incentive Sensitization - Responses0.00.00.1-0.20.10.1-0.10.1-0.1-0.1-0.10.3-0.30.3
Incentive Sensitization - Breakpoint0.00.00.2-0.10.00.0-0.0-0.0-0.0-0.0-0.00.2-0.40.4
Sum of active levers in priming session hrs 5-60.30.30.9-0.20.40.4-0.40.5-0.4-0.4-0.40.11.0-1.0
Progressive ratio0.40.50.60.7-0.7-0.80.7-0.70.80.70.7-0.6-0.80.8
Food seeking constrained by brief footshock1.82.23.21.8-1.5-1.71.6-1.51.61.61.6-1.8-0.60.6
Seeking ratio, punishment vs. effort0.20.20.50.5-0.4-0.40.3-0.20.30.40.4-0.70.6-0.6
Retroperitoneal fat weight0.20.61.1-1.00.80.8-0.80.7-0.8-0.8-0.81.0-0.20.2
Reaction time number correct2.43.54.22.0-2.0-1.92.0-2.01.91.92.0-2.0-1.21.2
Reaction time mean minus median0.10.20.3-0.50.40.4-0.30.3-0.3-0.3-0.30.6-0.40.4
Reaction time mean minus median AUC0.10.10.2-0.50.30.3-0.30.3-0.3-0.3-0.30.4-0.20.2
Reaction time num false alarms0.60.91.31.0-1.1-0.91.0-1.00.91.01.0-1.1-0.40.4
Reaction time num false alarms AUC1.11.52.01.4-1.4-1.31.3-1.31.31.31.3-1.4-0.70.7
Reaction time trials correct on left2.43.54.22.0-2.0-1.92.0-2.01.91.92.0-2.0-1.21.2
Reaction time trials on left2.43.44.12.0-2.0-1.92.0-2.01.91.92.0-2.0-1.31.3
Reaction time mean0.81.11.7-1.21.11.1-1.11.1-1.1-1.1-1.11.30.3-0.3
Reaction time mean AUC0.50.71.1-1.00.90.9-0.90.8-0.9-0.9-0.91.10.1-0.1
Median of all reaction times0.50.71.1-1.00.90.9-0.90.9-0.9-0.9-0.91.00.3-0.3
Reaction time omissions1.21.63.40.9-1.1-1.11.2-1.21.21.11.1-0.7-1.91.9
Reaction time false alarm rate0.10.10.20.3-0.4-0.30.3-0.30.30.30.3-0.4-0.20.2
Reaction time premature initiation rate0.70.91.01.0-0.9-1.01.0-1.01.00.91.0-0.9-0.90.9
Reaction time premature initiations2.02.93.41.8-1.8-1.71.8-1.81.71.71.8-1.8-1.21.2
Std. dev. reaction times0.30.40.9-0.90.70.6-0.60.6-0.6-0.6-0.60.9-0.40.4
Reaction time trials completed2.43.44.12.0-2.0-1.92.0-2.01.91.92.0-2.0-1.31.3
Reaction time trials AUC2.63.74.42.1-2.1-1.92.0-2.11.92.02.0-2.0-1.41.4
Run reversals in cocaine runway, females1.11.11.2-1.00.91.1-1.01.0-1.1-1.1-1.00.91.0-1.0
Run reversals in cocaine runway, males0.90.91.21.1-1.0-1.01.0-0.91.01.01.0-1.1-0.40.4
Latency to leave start box in cocaine runway0.20.20.3-0.40.40.5-0.40.4-0.5-0.5-0.40.40.4-0.4
Latency to leave start box in cocaine runway, F0.20.20.3-0.40.40.6-0.40.4-0.5-0.5-0.40.40.4-0.4
Latency to leave start box in cocaine runway, M0.10.10.1-0.30.30.3-0.30.3-0.3-0.3-0.30.20.3-0.3
Std. dev. time between licks in bursts0.70.91.7-0.70.90.8-0.91.0-0.9-0.8-0.90.61.3-1.3
Total sessions with >9 infusions0.20.21.0-0.10.30.3-0.30.4-0.3-0.3-0.30.01.0-1.0
Short access day 1 total inactive lever presses0.10.10.2-0.20.20.3-0.30.3-0.3-0.3-0.30.20.4-0.4
Short access day 10 total inactive lever presses0.40.50.90.5-0.6-0.60.7-0.70.60.60.6-0.5-0.90.9
Short access day 1 total infusions0.20.20.20.5-0.4-0.40.4-0.50.40.40.4-0.4-0.40.4
Short access day 10 total infusions0.50.50.7-0.70.70.8-0.70.7-0.8-0.7-0.70.50.9-0.9
Short access total infusions0.30.30.5-0.50.50.5-0.50.6-0.6-0.6-0.50.40.7-0.7
Short access day 1 locomotion0.90.91.4-0.80.91.0-0.90.9-1.0-1.0-0.90.71.2-1.2
Short access day 10 total locomotion0.60.70.8-0.80.80.8-0.90.9-0.9-0.9-0.90.80.8-0.8
Short access total locomotion0.10.10.3-0.20.30.3-0.30.3-0.3-0.3-0.30.20.5-0.5
One hour access (0.3 mA shock)0.00.10.10.3-0.2-0.30.2-0.20.20.20.2-0.3-0.00.0
Compulsive drug intake0.00.00.0-0.20.10.1-0.10.1-0.1-0.1-0.10.2-0.10.1
One hour access (shock baseline)0.00.00.2-0.10.20.1-0.20.2-0.2-0.2-0.20.00.4-0.4
Social response proportion0.30.30.70.4-0.5-0.40.5-0.60.40.40.5-0.3-0.80.8
Social responses0.10.10.3-0.10.20.3-0.30.3-0.3-0.3-0.20.10.6-0.6
Social time0.81.11.60.9-1.0-1.01.0-1.11.01.01.0-0.8-1.31.3
Soleus weight0.00.10.1-0.10.20.2-0.20.2-0.2-0.2-0.20.10.3-0.3
Bone: stiffness1.72.74.21.9-1.7-1.81.7-1.61.81.81.8-2.0-0.60.6
Tibialis anterior weight0.31.11.41.0-1.0-1.01.0-1.11.01.01.0-0.8-1.21.2
Time to tail flick, vehicle, before self-admin0.70.71.20.7-0.8-0.80.8-0.80.90.80.8-0.6-1.11.1
Time to tail flick, vehicle, after self-admin0.30.30.8-0.30.50.5-0.50.5-0.5-0.5-0.50.20.9-0.9
Time to tail flick, test, before self-admin0.00.00.10.3-0.2-0.20.2-0.20.20.20.2-0.30.1-0.1
Time to tail flick, test, after self-admin1.61.71.91.3-1.4-1.31.4-1.41.31.41.4-1.3-1.01.0
Delta time to tail flick, vehicle, before/after SA0.30.31.5-0.10.30.3-0.40.4-0.4-0.4-0.3-0.11.2-1.2
Delta time to tail flick, test, before/after SA1.00.91.10.9-1.0-1.01.0-1.01.01.01.0-1.0-0.80.8
Tibia length0.51.32.01.3-1.2-1.31.2-1.11.31.31.3-1.4-0.50.5
Ambulatory time before self-admin0.10.10.3-0.40.30.3-0.30.2-0.3-0.3-0.30.5-0.40.4
Ambulatory time after self-admin0.00.00.0-0.10.10.0-0.10.1-0.1-0.1-0.10.1-0.00.0
Bone: tissue strength0.20.20.40.5-0.4-0.50.4-0.30.50.50.5-0.70.2-0.2
Total heroin consumption1.11.31.71.3-1.2-1.31.2-1.21.21.21.2-1.3-0.70.7
Bone: trabecular number0.00.10.20.2-0.2-0.10.1-0.10.10.10.2-0.40.5-0.5
Bone: trabecular spacing0.00.00.1-0.20.20.1-0.20.2-0.1-0.1-0.20.3-0.10.1
Bone: trabecular thickness0.10.10.10.4-0.3-0.40.4-0.30.40.30.3-0.3-0.30.3
Bone: trabecular tissue density0.20.20.40.6-0.6-0.40.5-0.50.40.40.5-0.7-0.00.0
Water consumed over 24 hours2.93.54.01.9-2.0-1.92.0-2.01.91.92.0-1.9-1.51.5
Number of responses in last shaping day0.30.30.5-0.70.60.6-0.60.6-0.6-0.6-0.60.70.0-0.0