Hub : Genes

LOC681367

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 RMTg gene expression LOC681367 0.14 0.09 4.4e-03 0.06 0.08 0.07 0.07 8.1e-03 3.9e-03 6.2e-03 5.6e-03
2 pVTA gene expression LOC681367 0.12 0.08 7.1e-05 0.08 0.08 0.06 0.07 2.1e-04 1.8e-04 1.9e-03 4.8e-04
3 NAcc gene expression LOC681367 0.11 0.06 8.9e-16 0.15 0.14 0.15 0.14 4.4e-17 3.2e-16 1.2e-16 1.6e-16
4 BLA gene expression LOC681367 0.18 0.1 9.8e-10 0.19 0.17 0.21 0.18 1.5e-10 1.2e-09 2.5e-11 4.4e-10
5 PL gene expression LOC681367 0.14 0.07 5.6e-17 0.16 0.16 0.15 0.15 1.3e-17 9.3e-17 9.6e-16 1.1e-16
6 IL gene expression LOC681367 0.14 0.1 6.7e-03 0.03 0.06 0.01 0.07 6.5e-02 1.3e-02 1.8e-01 1.1e-02
7 Liver gene expression LOC681367 0.21 0.09 0.0e+00 0.22 0.22 0.21 0.22 1.8e-24 1.7e-23 4.1e-23 3.7e-24
8 Adipose gene expression LOC681367 0.08 0.05 2.2e-10 0.09 0.09 0.09 0.08 9.3e-10 7.8e-10 6.6e-10 1.9e-09
9 Brain gene expression LOC681367 0.09 0.05 2.4e-09 0.09 0.1 0.09 0.09 6.3e-09 3.1e-09 2.2e-08 1.0e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.30.51.0-0.9-0.90.71.00.6-0.60.70.40.0
Area under the delay curve8.38.711.6-2.8-2.73.42.33.2-3.13.02.8-3.2
BMI with tail4.313.916.93.94.0-3.8-4.1-3.83.7-3.7-3.42.9
BMI without tail12.726.329.65.45.4-5.1-5.4-5.25.1-5.1-4.84.4
Body weight3.113.014.73.83.8-3.6-3.4-3.73.6-3.5-3.73.3
Weight adjusted by age0.20.30.50.60.6-0.2-0.7-0.40.5-0.60.20.4
Bone surface1.32.23.4-1.7-1.71.41.81.4-1.41.61.2-0.9
Bone volume0.50.81.4-1.0-1.10.91.20.9-0.81.00.6-0.4
Breakpoint value in progressive ratio session0.10.10.30.10.10.2-0.40.1-0.2-0.00.5-0.3
Number of licking bursts3.94.57.11.81.8-2.1-2.0-2.12.1-2.1-2.22.7
Context. condit. distance diff. score0.20.20.50.40.4-0.4-0.3-0.40.5-0.3-0.70.6
Locomotion velocity, session 10.60.61.11.01.0-0.7-1.0-0.70.7-0.7-0.60.0
Locomotion distance, session 12.32.93.61.91.9-1.8-1.3-1.81.7-1.7-1.81.5
Locomotion velocity, session 25.46.38.73.02.9-2.5-2.2-2.52.5-2.6-2.51.8
Locomotion distance, session 21.42.02.51.61.6-1.5-1.3-1.51.4-1.3-1.41.0
Locomotion velocity, session 30.50.61.01.01.0-0.5-1.0-0.60.6-0.7-0.80.0
Locomotion distance, session 30.80.91.7-0.7-0.71.00.90.9-0.91.00.8-1.3
Stereotopy head waving bouts, day 31.41.72.21.21.2-1.3-1.5-1.31.3-1.2-1.31.2
Stereotopy head waving duration, day 32.12.53.41.71.7-1.5-1.8-1.61.6-1.6-1.51.2
Locomotion velocity, session 70.20.20.50.70.7-0.4-0.4-0.40.4-0.4-0.4-0.3
Locomotion distance, session 70.10.10.40.50.5-0.3-0.7-0.30.3-0.1-0.1-0.3
Stereotopy head waving bouts, day 70.20.20.40.40.4-0.5-0.5-0.50.5-0.4-0.50.6
Stereotopy head waving duration, day 70.00.10.1-0.3-0.30.20.30.2-0.20.1-0.10.3
Locomotion velocity, session 80.60.71.11.00.9-0.7-0.9-0.70.7-0.9-1.00.7
Locomotion distance, session 81.11.72.11.41.3-1.3-1.2-1.31.3-1.1-1.51.1
Degree of sensitization distance1.91.92.81.41.5-1.5-1.7-1.41.4-1.3-1.11.0
Degree of sensitization stereotypy0.40.40.6-0.8-0.80.70.70.7-0.70.80.4-0.4
Conditioned locomotion1.92.24.0-1.2-1.11.51.51.5-1.51.61.4-2.0
Cocaine response after cond. corrected0.20.20.4-0.6-0.60.5-0.00.5-0.50.50.5-0.4
Cocaine response after cond. not corrected0.40.40.6-0.7-0.70.70.20.7-0.70.60.7-0.7
Cocaine response before conditioning0.00.00.10.30.3-0.2-0.1-0.10.0-0.30.0-0.2
Saline control response0.00.00.00.10.10.1-0.00.1-0.10.00.1-0.2
Bone: connectivity density0.71.22.4-1.4-1.40.91.50.9-0.81.00.8-0.1
Bone: cortical apparent density0.81.11.5-0.9-0.91.11.21.2-1.11.01.0-1.1
Bone: cortical area0.60.91.71.31.3-0.8-0.4-0.90.9-0.8-1.30.3
Bone: cortical porosity0.10.10.20.30.3-0.40.2-0.40.4-0.3-0.50.4
Bone: cortical porosity0.10.10.10.30.3-0.30.2-0.40.4-0.2-0.30.1
Bone: cortical thickness0.81.42.51.61.5-1.1-0.4-1.11.1-1.1-1.50.5
Bone: cortical thickness0.00.00.1-0.1-0.20.00.10.1-0.00.1-0.30.2
Bone: cortical tissue density0.71.01.2-0.8-0.91.11.11.1-1.00.91.0-1.0
Condit. Reinf. active minus inactive responses1.82.03.81.41.4-1.4-2.0-1.41.4-1.4-1.21.3
Condit. Reinf. active-inactive response ratio0.30.41.00.40.4-0.5-1.0-0.50.6-0.6-0.30.8
Condit. Reinf. active responses2.93.64.02.01.9-1.9-2.0-1.91.9-1.9-1.91.8
Condit. Reinf. inactive responses2.32.73.71.71.7-1.7-1.2-1.71.7-1.6-1.91.6
Incentive salience index mean2.32.84.11.91.8-1.6-2.0-1.61.6-1.7-1.51.3
Condit. Reinf. lever presses4.05.36.82.62.6-2.2-2.3-2.32.3-2.3-2.21.8
Condit. Reinf. active minus inactive responses0.00.10.3-0.1-0.1-0.0-0.2-0.00.0-0.3-0.10.5
Condit. Reinf. active-inactive response ratio0.90.92.20.70.6-0.9-0.8-0.80.8-1.2-0.91.5
Condit. Reinf. active responses0.00.00.0-0.1-0.10.1-0.10.1-0.1-0.10.00.2
Condit. Reinf. inactive responses0.10.10.3-0.00.00.3-0.10.3-0.20.30.2-0.5
Condit. Reinf. lever presses0.50.71.20.70.7-0.8-0.6-0.80.8-0.9-0.91.1
Condit. Reinf. lever reinforcers received0.00.00.0-0.1-0.10.1-0.00.2-0.1-0.00.00.1
Conditioned reinforcement - actives0.90.92.0-0.7-0.60.90.30.9-0.91.01.2-1.4
Conditioned reinforcement - inactives0.80.92.01.11.1-1.0-1.4-1.00.9-0.8-0.50.3
Conditioned locomotion0.00.00.20.10.1-0.1-0.2-0.20.20.00.4-0.1
Patch foraging indifference point 0 sec0.81.21.71.11.1-1.1-1.3-1.11.3-1.1-0.81.1
Patch foraging indifference point AUC0.80.91.81.21.3-0.7-1.4-0.80.8-0.9-0.60.0
Delay disc. indifference point, 0s delay1.41.62.3-1.3-1.21.50.11.4-1.31.11.5-1.3
Delay disc. indifference point, 16s delay12.112.213.6-3.3-3.33.73.33.7-3.63.53.5-3.7
Delay disc. indifference point, 2s delay3.13.45.4-1.7-1.72.30.82.0-2.01.81.9-2.0
Delay disc. indifference point, 24s delay1.41.31.8-1.1-1.11.31.31.3-1.31.00.9-0.9
Delay disc. indifference point, 4s delay3.03.26.4-1.3-1.22.20.61.9-1.71.92.0-2.5
Delay disc. indifference point, 8s delay5.05.27.1-2.1-2.02.71.72.4-2.32.42.1-2.6
Indifference point function ln k0.40.50.9-0.9-0.80.7-0.00.7-0.80.80.9-0.7
Indifference point function log k0.40.50.9-0.9-0.80.7-0.00.7-0.80.80.9-0.7
Patch foraging total patch changes 0 sec1.01.72.91.31.3-1.3-1.7-1.31.4-1.2-0.91.2
Patch foraging total patch changes 12 sec1.01.32.11.51.5-0.9-1.4-1.01.1-1.0-1.00.4
Patch foraging total patch changes 18 sec1.41.93.31.61.6-1.2-1.8-1.21.3-1.2-1.20.7
Patch foraging total patch changes 24 sec0.81.01.41.21.2-0.9-1.2-1.01.0-0.9-0.80.6
Patch foraging total patch changes 6 sec2.13.13.82.01.9-1.7-1.8-1.71.9-1.8-1.61.5
Patch foraging time to switch 0 sec4.97.514.9-2.9-3.02.73.92.7-2.72.61.9-1.7
Patch foraging water rate 0 sec2.74.310.12.52.6-1.9-3.2-1.91.9-1.7-1.30.5
Patch foraging water rate 12 sec5.68.511.73.23.2-2.9-3.4-2.92.9-2.8-2.72.1
Patch foraging water rate 18 sec1.21.72.71.41.5-1.2-1.6-1.21.3-1.2-1.20.8
Patch foraging water rate 24 sec2.23.07.11.81.9-1.7-2.7-1.71.7-1.6-1.21.1
Patch foraging water rate 6 sec0.40.62.40.80.9-0.5-1.6-0.50.5-0.4-0.5-0.2
Seeking ratio, delayed vs. immediate footshock2.02.33.0-1.7-1.71.51.11.4-1.51.71.6-1.2
Distance traveled before self-admin0.10.10.30.50.5-0.4-0.3-0.40.5-0.2-0.50.1
Distance traveled after self-admin3.74.15.12.12.1-2.1-1.4-2.22.3-2.1-2.01.8
Extensor digitorum longus weight0.10.30.50.70.7-0.6-0.5-0.60.6-0.6-0.70.3
Bone: elastic displacement0.30.30.5-0.5-0.60.70.50.7-0.70.50.3-0.5
Bone: elastic work0.10.10.40.20.1-0.00.1-0.00.1-0.2-0.60.4
Bone: endosteal estimation0.40.81.2-1.1-1.00.9-0.10.9-0.91.11.1-0.7
Bone: endosteal perimeter0.00.00.10.00.00.0-0.3-0.10.10.1-0.1-0.0
Epididymis fat weight2.15.06.52.22.1-2.2-2.0-2.22.2-2.3-2.32.5
Delta time in closed arm before/after self-admin0.20.20.50.20.2-0.5-0.5-0.50.5-0.3-0.10.7
Delta time in open arm before/after self-admin0.40.30.6-0.6-0.60.60.60.6-0.60.60.2-0.7
Diff in mean of infusions in LGA sessions0.60.62.70.80.9-0.6-1.7-0.60.5-0.60.40.1
Delay discount exponential model param8.08.411.62.72.7-3.4-2.3-3.13.0-2.9-2.73.2
Extinction: sum of active levers before priming0.00.00.20.10.1-0.0-0.4-0.10.0-0.10.1-0.0
Active lever presses in extinction session 60.20.20.70.40.5-0.0-0.8-0.1-0.0-0.30.4-0.4
Bone: final force0.50.81.41.00.9-0.8-1.1-0.80.8-0.6-1.20.7
Bone: final moment0.40.71.41.00.9-0.7-1.2-0.70.7-0.6-1.00.4
Food consumed during 24 hour testing period0.50.61.00.91.0-0.7-1.0-0.70.7-0.8-0.60.3
Glucose5.27.98.52.82.8-2.9-2.5-2.82.8-2.8-2.92.9
Heart weight1.31.82.4-1.2-1.21.31.11.4-1.51.51.3-1.6
Delay discount hyperbolic model param7.17.510.72.52.5-3.3-2.0-3.02.8-2.8-2.63.0
Intermittent access intake day 1-15 change0.10.10.20.40.4-0.2-0.2-0.10.1-0.10.1-0.2
Intermittent access intake escalation0.00.00.10.10.1-0.00.20.1-0.10.00.1-0.2
Intermittent access intake escalation 20.10.10.20.50.5-0.2-0.2-0.20.2-0.2-0.2-0.2
Intermitt. access day 1 inactive lever presses1.41.52.11.31.3-1.5-1.1-1.31.2-1.3-1.21.0
Intermitt. access day 15 inactive lever presses2.02.23.01.51.6-1.7-1.6-1.51.5-1.4-1.31.2
Intermitt. access escalation Index0.00.00.1-0.2-0.2-0.00.30.0-0.00.1-0.10.0
Intermittent access day 1 total infusions0.60.71.20.60.6-1.1-0.8-1.11.0-0.8-0.41.1
Intermittent access day 15 total infusions0.30.40.80.40.5-0.9-0.5-0.80.8-0.5-0.20.7
Intermittent access terminal intake (last 3 days)0.20.20.50.20.3-0.7-0.2-0.60.6-0.3-0.10.6
Intermittent access total infusions0.10.20.40.10.1-0.7-0.1-0.50.5-0.30.00.6
Intermittent access day 1 locomotion0.30.30.80.20.2-0.7-0.2-0.70.7-0.4-0.70.9
Intermittent access day 15 total locomotion0.30.40.50.60.6-0.7-0.5-0.70.7-0.5-0.50.6
Intermittent access total locomotion0.10.10.4-0.2-0.2-0.40.4-0.30.3-0.1-0.30.6
Intermittent access standard deviation3.33.55.4-2.0-2.11.82.31.8-1.81.81.6-1.3
Left kidney weight0.20.51.31.11.1-0.6-0.5-0.50.5-0.5-0.7-0.2
Right kidney weight0.10.20.60.60.60.1-0.4-0.0-0.00.10.0-0.8
Cocaine induced anxiety0.10.10.30.30.3-0.4-0.1-0.30.3-0.4-0.30.5
Post-drug Anxiety0.00.00.2-0.1-0.2-0.10.10.1-0.1-0.1-0.10.4
Baseline Anxiety0.20.20.3-0.5-0.50.40.30.6-0.60.50.4-0.4
Tail length1.95.66.62.62.5-2.3-2.0-2.42.4-2.4-2.52.3
Length with tail0.10.30.90.70.5-0.40.1-0.40.5-0.4-0.90.6
Length without tail2.76.08.9-2.4-2.52.53.02.5-2.52.41.9-2.1
Times rat made contact with spout5.36.17.32.32.3-2.4-2.6-2.42.5-2.6-2.52.7
Lifetime Intake0.10.10.2-0.4-0.4-0.10.30.0-0.00.30.4-0.0
Liver weight, left0.40.61.11.11.1-0.7-1.0-0.70.6-0.7-0.70.2
Liver weight, right0.71.11.81.11.0-0.9-1.2-0.90.9-1.0-1.31.0
Locomotor activity2.23.54.51.91.8-1.9-1.2-1.81.9-2.1-2.12.1
Locomotor testing distance1.93.24.41.81.7-1.8-0.9-1.71.8-2.0-2.12.0
Locomotor testing rearing3.25.06.02.42.4-2.2-2.2-2.22.3-2.3-2.11.8
Locomotion in novel chamber0.70.91.2-0.9-0.91.00.51.0-1.01.11.1-1.1
Locomotion in novel chamber post-restriction1.41.73.7-0.9-0.81.10.61.2-1.31.41.9-1.8
Fecal boli incidents, locomotor time 10.40.41.4-0.3-0.30.5-0.30.8-0.70.70.3-1.2
Change in fecal boli incidents, locomotor task0.10.10.5-0.1-0.00.3-0.00.2-0.20.30.7-0.5
Time >=10cm from walls, locomotor time 10.40.41.40.60.7-0.5-1.2-0.50.7-0.4-0.30.1
Bouts of movement, locomotor time 10.10.10.3-0.6-0.6-0.10.40.1-0.00.2-0.30.3
Total resting periods, locomotor time 10.20.30.70.00.0-0.6-0.1-0.50.6-0.4-0.80.7
Rest time, locomotor task time 10.70.71.0-0.9-0.90.8-0.10.9-0.81.01.0-1.0
Distance moved, locomotor task time 10.10.10.40.20.10.10.6-0.20.2-0.3-0.10.3
Vertical activity count, locomotor time 10.70.71.3-0.7-0.71.11.00.9-0.90.70.6-0.7
Time >=10cm from walls, locomotor time 20.60.61.40.91.0-0.6-1.2-0.70.9-0.6-0.30.2
Bouts of movement, locomotor time 20.30.30.60.60.6-0.6-0.0-0.70.8-0.5-0.20.6
Total resting periods, locomotor time 20.10.10.20.10.2-0.30.1-0.30.4-0.10.20.4
Rest time, locomotor task time 20.60.61.1-1.1-1.10.80.20.8-0.80.90.6-0.5
Distance moved, locomotor task time 21.01.21.61.11.1-1.1-0.7-1.21.2-1.3-0.81.0
Vertical activity count, locomotor time 20.20.20.4-0.1-0.10.6-0.10.4-0.40.30.6-0.6
Light reinforcement 12.03.74.42.12.1-2.0-1.9-1.92.0-1.9-1.81.5
Light reinforcement 22.73.64.81.81.7-2.1-1.3-2.02.0-1.9-1.92.2
Bone: marrow area0.40.91.3-1.1-1.11.00.00.9-1.01.21.1-0.8
Bone: maximum diameter0.20.30.70.80.8-0.5-0.3-0.50.5-0.4-0.6-0.1
Bone: maximum force0.00.10.30.20.1-0.2-0.4-0.20.2-0.0-0.50.4
Bone: maximum moment0.00.00.20.20.1-0.1-0.5-0.10.10.1-0.30.1
Mean time between licks in bursts1.41.93.1-1.8-1.71.31.21.3-1.31.41.5-0.7
Mean num. licks in bursts0.50.61.3-0.6-0.60.80.50.8-0.70.70.9-1.1
Cd content in liver1.11.21.7-1.0-1.01.11.11.0-1.01.11.1-1.3
Co content in liver0.00.00.10.00.1-0.2-0.2-0.20.2-0.20.20.1
Cu content in liver0.60.71.7-0.6-0.51.00.40.9-0.80.91.0-1.3
Fe content in liver0.50.61.8-0.6-0.70.61.30.7-0.60.80.5-0.7
K content in liver0.60.61.7-0.9-1.10.61.30.6-0.60.60.10.3
Mg content in liver1.92.02.4-1.4-1.51.51.51.5-1.51.41.0-1.3
Mn content in liver0.91.02.20.70.8-1.0-1.5-1.01.0-1.1-0.51.2
Na content in liver0.10.10.30.40.3-0.1-0.6-0.10.1-0.2-0.40.1
Rb content in liver6.58.18.8-2.8-2.82.92.82.9-2.93.02.6-2.8
Se content in liver0.10.10.20.40.5-0.30.1-0.40.4-0.4-0.20.0
Sr content in liver0.70.70.90.90.9-0.9-0.9-0.90.9-0.9-0.60.5
Zn content in liver4.65.18.5-2.0-1.92.21.82.3-2.32.32.2-2.9
Bone: minimum diameter0.30.50.70.80.8-0.7-0.5-0.80.8-0.4-0.90.4
Time in familiar zone, hab. session 10.60.61.11.01.0-0.8-0.7-0.70.7-0.7-0.7-0.0
Time in novel zone, hab. session 10.90.91.4-1.2-1.10.90.60.9-0.90.91.2-0.4
Total zone transitions, hab. session 14.36.06.92.62.6-2.6-2.1-2.62.5-2.3-2.52.2
Total locomotion distance, hab. session 14.76.69.12.82.8-2.5-3.0-2.62.5-2.4-2.42.0
Locomotion velocity, hab. session 14.26.08.12.72.7-2.4-2.8-2.42.3-2.3-2.31.8
Time in familiar zone, hab. session 22.22.35.1-1.6-1.71.42.31.4-1.51.50.9-1.0
Time in novel zone, hab. session 20.50.52.10.60.7-0.6-1.4-0.60.7-0.6-0.10.2
Total zone transitions, hab. session 22.93.75.91.81.7-2.0-1.1-2.02.0-2.0-2.22.4
Total locomotion distance, hab. session 23.34.34.92.02.0-2.2-2.0-2.12.1-2.0-2.02.2
Locomotion velocity, hab. session 22.53.44.21.81.7-1.9-1.7-1.91.9-1.8-1.82.1
Novel to familiar place preference ratio0.10.10.10.30.3-0.3-0.4-0.20.3-0.4-0.30.3
Novelty place preference0.00.00.00.10.1-0.0-0.20.0-0.0-0.1-0.10.0
Time in novel zone, NPP test0.00.00.10.10.1-0.0-0.30.0-0.0-0.1-0.0-0.0
Total zone transitions, NPP test7.09.911.13.33.2-3.3-2.5-3.33.2-3.1-3.33.1
Total locomotion distance, NPP test6.38.69.03.03.0-3.0-3.0-2.92.9-2.9-2.92.9
Locomotion velocity, NPP test6.89.610.13.23.1-3.1-2.9-3.13.0-3.1-3.23.1
Intraocular pressure1.01.42.1-1.3-1.21.01.11.1-1.11.11.5-1.1
Delta distance traveled before/after self-admin4.65.06.12.12.1-2.3-1.7-2.42.4-2.5-2.12.4
Delta ambulatory time before/after self-admin3.84.25.02.02.0-2.0-1.7-2.22.2-2.2-2.02.2
Parametrial fat weight6.212.113.23.63.5-3.6-2.7-3.53.6-3.6-3.63.5
Pavlov. Cond. lever latency2.43.04.6-2.1-2.11.71.91.7-1.71.61.5-1.0
Pavlov. Cond. magazine entry latency0.60.81.71.21.3-0.9-1.0-0.90.8-0.8-0.6-0.0
Pavlov. Cond. change in total contacts1.92.03.11.71.8-1.5-1.6-1.51.5-1.2-0.90.8
Pavlov. Cond. index score2.43.15.02.22.2-1.7-1.8-1.71.7-1.6-1.40.8
Pavlov. Cond. latency score1.62.13.71.91.9-1.4-1.5-1.41.4-1.3-1.20.5
Pavlov. Cond. lever contacts3.54.15.72.42.4-2.0-2.3-2.02.0-1.8-1.71.3
Pavlov. Cond. magazine entry number1.72.13.5-1.8-1.91.51.61.5-1.41.31.0-0.6
Pavlov. Cond. intertrial magazine entries0.80.91.3-1.1-1.11.10.11.0-1.01.11.0-0.8
Pavlov. Cond. lever-magazine prob. diff.2.32.84.62.12.1-1.7-1.9-1.71.7-1.5-1.30.7
Pavlov. Cond. response bias4.15.07.02.62.6-2.3-2.3-2.32.2-2.1-1.91.4
Pavlov. Cond. lever latency2.43.34.4-1.8-1.71.91.51.9-1.81.81.9-2.1
Pavlov. Cond. magazine entry latency1.82.12.71.51.4-1.6-1.2-1.51.4-1.3-1.61.5
Pavlov. Cond. change in total contacts2.43.44.51.81.7-1.8-1.7-1.81.8-1.8-2.02.1
Pavlov. Cond. index score4.55.86.52.42.3-2.5-2.1-2.52.4-2.4-2.62.5
Pavlov. Cond. latency score4.96.16.92.52.4-2.6-2.0-2.52.5-2.4-2.62.6
Pavlov. Cond. lever contacts2.83.84.71.91.8-2.0-1.6-2.01.9-1.9-2.22.2
Pavlov. Cond. magazine entry number0.81.01.7-1.0-0.91.10.71.0-0.90.81.3-1.0
Pavlov. Cond. intertrial magazine entries0.00.00.10.00.00.10.20.00.0-0.00.1-0.1
Pavlov. Cond. lever-magazine prob. diff.4.55.86.62.42.3-2.5-2.1-2.42.4-2.3-2.52.6
Pavlov. Cond. response bias0.91.32.11.11.0-1.1-0.8-1.11.1-1.0-1.51.4
Time in closed arm before self-admin0.20.20.4-0.6-0.70.20.60.5-0.40.30.10.1
Time in closed arm after self-admin0.10.10.5-0.4-0.5-0.20.4-0.10.2-0.0-0.00.7
Time in open arm before self-admin2.72.94.82.02.1-1.6-2.2-1.81.7-1.5-1.01.0
Time in open arm after self-admin0.50.61.20.91.0-0.6-1.1-0.80.7-0.6-0.60.1
Bone: periosteal estimation0.10.10.50.40.4-0.2-0.7-0.20.2-0.0-0.2-0.2
Bone: periosteal perimeter0.61.01.91.21.1-1.0-0.6-1.01.0-0.8-1.40.7
Bone: post-yield work0.00.00.1-0.1-0.1-0.2-0.1-0.20.10.10.00.4
Progressive ratio test 1 active lever presses1.11.12.00.80.8-1.3-0.7-1.21.2-1.1-0.81.4
Progressive ratio test 1 breakpoint0.90.91.50.80.8-1.2-0.7-1.11.1-1.0-0.61.2
Progressive ratio test 1 inactive lever presses1.01.11.61.01.1-1.3-1.2-1.21.1-1.0-0.60.7
Progressive ratio test 2 active lever presses1.21.31.91.11.2-1.4-1.3-1.31.3-1.0-0.50.8
Progressive ratio test 2 breakpoint1.82.02.71.41.5-1.7-1.6-1.61.5-1.3-0.91.1
Progressive ratio test 2 inactive lever presses0.50.61.10.80.8-1.0-1.0-0.90.9-0.7-0.40.5
Incentive Sensitization - Responses1.21.21.61.21.3-1.3-1.2-1.21.2-1.0-0.60.7
Incentive Sensitization - Breakpoint1.21.21.61.21.3-1.3-1.2-1.21.2-1.0-0.60.7
Sum of active levers in priming session hrs 5-61.01.02.5-0.5-0.50.90.21.0-1.10.91.4-1.6
Progressive ratio0.60.71.0-0.7-0.81.00.61.0-0.90.80.5-0.8
Food seeking constrained by brief footshock0.10.10.90.20.1-0.10.1-0.20.1-0.2-0.90.4
Seeking ratio, punishment vs. effort0.60.71.20.80.8-0.9-0.4-1.00.8-0.9-1.10.8
Retroperitoneal fat weight1.75.67.42.72.7-2.3-2.6-2.32.3-2.3-2.21.5
Reaction time number correct0.20.41.1-0.00.10.4-1.10.3-0.40.40.7-1.0
Reaction time mean minus median0.20.21.1-0.3-0.40.51.00.5-0.50.20.1-0.2
Reaction time mean minus median AUC0.40.61.2-0.8-0.90.81.10.8-0.80.50.6-0.3
Reaction time num false alarms0.81.12.2-1.0-1.01.01.51.0-0.91.00.9-0.9
Reaction time num false alarms AUC0.50.71.1-0.8-0.80.81.10.9-0.80.80.8-0.9
Reaction time trials correct on left0.20.41.1-0.00.10.4-1.10.3-0.40.40.7-1.0
Reaction time trials on left0.20.31.10.00.10.3-1.10.3-0.30.30.7-0.9
Reaction time mean0.30.42.3-0.7-0.80.21.50.3-0.30.3-0.00.6
Reaction time mean AUC0.30.52.5-0.7-0.80.11.60.2-0.30.2-0.10.7
Median of all reaction times0.30.41.8-0.6-0.6-0.11.30.0-0.10.1-0.20.8
Reaction time omissions0.50.71.00.80.7-0.9-0.5-0.80.8-0.9-0.81.0
Reaction time false alarm rate0.71.03.2-1.1-1.10.91.80.9-0.80.80.7-0.5
Reaction time premature initiation rate1.01.41.61.21.2-1.3-1.2-1.21.3-1.1-1.11.1
Reaction time premature initiations1.01.43.31.31.3-1.1-1.8-1.11.1-1.0-0.80.6
Std. dev. reaction times0.30.42.2-0.6-0.70.41.50.4-0.40.30.10.3
Reaction time trials completed0.20.31.10.00.10.3-1.10.3-0.30.30.7-0.9
Reaction time trials AUC0.20.31.60.20.20.2-1.30.2-0.20.20.6-0.8
Run reversals in cocaine runway, females0.70.61.11.11.1-0.7-0.8-0.70.7-0.7-0.80.4
Run reversals in cocaine runway, males0.10.10.10.20.3-0.4-0.2-0.30.3-0.10.1-0.0
Latency to leave start box in cocaine runway2.02.13.01.61.6-1.6-1.5-1.71.5-1.4-1.01.0
Latency to leave start box in cocaine runway, F0.20.30.50.40.4-0.6-0.2-0.70.5-0.4-0.70.5
Latency to leave start box in cocaine runway, M4.64.46.02.42.5-2.3-2.1-2.22.2-2.1-1.31.5
Std. dev. time between licks in bursts1.92.23.3-1.6-1.51.41.21.4-1.41.81.6-1.5
Total sessions with >9 infusions0.10.10.3-0.1-0.0-0.1-0.2-0.10.10.20.6-0.3
Short access day 1 total inactive lever presses0.10.10.40.40.5-0.3-0.6-0.30.3-0.1-0.0-0.2
Short access day 10 total inactive lever presses0.91.01.61.21.2-1.1-1.3-1.00.9-0.9-0.80.4
Short access day 1 total infusions0.40.40.9-0.6-0.50.50.30.5-0.50.70.9-0.8
Short access day 10 total infusions0.10.10.2-0.3-0.3-0.40.3-0.20.2-0.00.10.4
Short access total infusions0.40.40.7-0.8-0.80.40.70.5-0.50.70.7-0.4
Short access day 1 locomotion0.60.60.9-0.9-0.90.70.60.7-0.70.90.9-0.7
Short access day 10 total locomotion2.12.44.0-1.8-1.91.42.01.5-1.51.61.0-0.8
Short access total locomotion2.12.12.7-1.6-1.61.41.41.4-1.41.61.3-1.4
One hour access (0.3 mA shock)0.30.31.0-0.3-0.30.60.20.5-0.60.60.7-1.0
Compulsive drug intake0.10.10.30.00.10.4-0.30.3-0.30.10.2-0.6
One hour access (shock baseline)0.20.20.40.40.4-0.6-0.2-0.60.6-0.4-0.40.6
Social response proportion1.01.12.5-1.0-1.00.91.60.9-1.01.10.7-0.8
Social responses2.22.83.7-1.6-1.71.61.91.7-1.71.91.4-1.6
Social time1.41.84.9-0.8-0.81.30.91.4-1.41.41.2-2.2
Soleus weight0.41.11.71.21.2-1.1-0.5-1.11.0-1.0-1.30.9
Bone: stiffness0.00.00.0-0.1-0.10.0-0.0-0.0-0.00.2-0.10.1
Tibialis anterior weight0.20.60.70.80.8-0.8-0.7-0.80.8-0.8-0.70.9
Time to tail flick, vehicle, before self-admin0.20.20.3-0.4-0.50.30.50.4-0.50.40.5-0.5
Time to tail flick, vehicle, after self-admin2.72.95.1-1.8-1.91.72.31.7-1.71.61.3-0.9
Time to tail flick, test, before self-admin4.94.87.1-1.9-1.92.41.52.2-2.32.32.1-2.7
Time to tail flick, test, after self-admin0.60.61.1-0.6-0.71.10.00.9-1.00.70.7-0.7
Delta time to tail flick, vehicle, before/after SA0.70.71.1-0.8-0.81.01.11.0-0.90.70.5-0.4
Delta time to tail flick, test, before/after SA1.31.23.30.80.7-0.9-0.8-1.01.0-1.2-1.11.8
Tibia length2.26.28.32.82.9-2.5-2.4-2.52.4-2.6-2.31.9
Ambulatory time before self-admin0.00.00.30.10.10.2-0.10.2-0.10.30.0-0.5
Ambulatory time after self-admin3.43.84.62.12.1-1.9-1.5-2.12.2-2.0-1.81.8
Bone: tissue strength0.10.10.2-0.2-0.20.40.10.4-0.40.30.3-0.4
Total heroin consumption0.10.10.20.20.3-0.3-0.3-0.50.4-0.00.50.3
Bone: trabecular number0.40.61.2-0.9-1.00.71.10.7-0.70.90.5-0.4
Bone: trabecular spacing0.50.61.11.01.0-0.7-1.0-0.70.7-0.8-0.60.2
Bone: trabecular thickness0.70.91.4-1.1-1.20.91.20.8-0.81.00.6-0.4
Bone: trabecular tissue density0.20.31.4-0.00.10.3-0.30.3-0.30.30.8-1.2
Water consumed over 24 hours2.22.73.61.91.9-1.5-1.9-1.51.6-1.6-1.61.1
Number of responses in last shaping day0.10.10.30.40.5-0.3-0.6-0.30.4-0.3-0.30.0