Hub : Genes

LOC134483957

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability LOC134483957 0.72 0.09 0.0e+00 0.4 0.42 0.42 0.41 1.7e-47 7.8e-51 1.2e-50 4.2e-49
2 Adipose gene expression LOC134483957 0.86 0.06 0.0e+00 0.53 0.54 0.53 0.53 1.1e-68 5.9e-71 7.6e-70 1.2e-69
3 OFC gene expression LOC134483957 0.61 0.12 1.1e-16 0.49 0.49 0.51 0.51 1.7e-13 1.8e-13 3.6e-14 3.5e-14
4 pVTA gene expression LOC134483957 0.48 0.13 0.0e+00 0.51 0.5 0.53 0.52 1.1e-46 5.6e-46 4.1e-49 1.2e-48
5 PL gene expression LOC134483957 0.65 0.1 0.0e+00 0.67 0.67 0.67 0.67 3.0e-98 7.4e-99 1.1e-98 7.1e-99
6 Liver gene expression LOC134483957 0.39 0.13 0.0e+00 0.32 0.31 0.32 0.32 5.1e-36 1.2e-34 2.2e-36 1.1e-36
7 NAcc gene expression LOC134483957 0.52 0.08 0.0e+00 0.69 0.7 0.71 0.71 3.5e-146 1.5e-148 3.6e-153 1.5e-153
8 IL gene expression LOC134483957 0.76 0.1 0.0e+00 0.52 0.54 0.51 0.53 1.6e-14 2.4e-15 3.4e-14 7.4e-15
9 BLA gene expression LOC134483957 0.65 0.12 0.0e+00 0.57 0.61 0.61 0.61 2.1e-36 4.9e-40 7.1e-40 1.2e-39
10 Eye gene expression LOC134483957 0.56 0.18 3.0e-05 0.17 0.09 0.1 0.1 1.5e-03 1.8e-02 1.4e-02 1.3e-02
11 IC gene expression LOC134483957 0.66 0.11 0.0e+00 0.47 0.43 0.39 0.43 1.1e-21 1.5e-19 1.0e-17 8.2e-20
12 LHb gene expression LOC134483957 0.67 0.14 0.0e+00 0.52 0.49 0.42 0.51 2.3e-14 2.9e-13 3.2e-11 3.8e-14
13 Brain gene expression LOC134483957 0.62 0.1 0.0e+00 0.59 0.59 0.59 0.59 2.4e-68 2.4e-67 2.1e-67 7.9e-68
14 Brain mRNA stability LOC134483957 0.14 0.07 9.0e-13 0.14 0.12 0.12 0.13 5.4e-13 2.4e-11 1.6e-11 6.8e-12
15 RMTg gene expression LOC134483957 0.27 0.16 3.5e-04 0.1 0.06 0.08 0.07 1.0e-03 1.3e-02 3.2e-03 6.1e-03
16 RMTg mRNA stability LOC134483957 0.2 0.12 1.8e-03 0.02 0.04 0.02 0.04 8.7e-02 4.0e-02 7.9e-02 3.6e-02
17 BLA mRNA stability LOC134483957 0.21 0.16 9.5e-05 0.07 0.05 0.05 0.04 8.9e-05 1.2e-03 1.4e-03 2.0e-03
18 NAcc mRNA stability LOC134483957 0.12 0.08 1.2e-09 0.06 0.06 0.08 0.06 2.8e-09 1.0e-09 6.7e-12 3.2e-09
19 PL mRNA stability LOC134483957 0.03 0.02 4.2e-04 0.02 0.03 0.05 0.02 1.7e-03 5.4e-04 3.3e-06 1.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.61.13.4-1.2-1.1-1.00.8-0.9-0.9-0.9-1.3-1.40.90.91.00.91.00.9-1.9-0.60.50.7
Area under the delay curve0.10.20.80.00.10.4-0.30.20.30.30.20.0-0.3-0.3-0.3-0.3-0.4-0.4-0.7-0.9-0.70.0
BMI with tail1.96.716.9-3.4-3.0-2.52.3-2.6-2.4-2.5-2.8-3.22.52.52.42.42.42.3-4.1-1.31.61.5
BMI without tail0.63.08.2-2.1-1.9-1.71.7-1.8-1.7-1.7-1.5-2.11.71.71.61.61.71.7-2.9-1.10.70.8
Body weight2.912.517.2-4.1-4.0-3.73.7-3.8-3.7-3.8-3.6-4.03.73.63.73.73.63.5-4.11.12.31.8
Weight adjusted by age0.82.22.9-1.3-1.4-1.71.6-1.6-1.6-1.6-1.5-1.41.51.71.41.51.71.7-1.21.11.61.0
Bone surface4.69.113.2-3.3-3.4-3.23.0-3.1-3.0-3.1-3.6-3.43.03.03.13.03.13.0-3.11.42.42.0
Bone volume1.63.35.4-2.1-2.1-1.91.7-1.8-1.7-1.8-2.3-2.11.81.71.81.81.81.7-2.00.41.61.3
Breakpoint value in progressive ratio session2.54.55.5-2.3-2.2-2.32.2-2.2-2.2-2.2-2.3-2.22.32.32.22.22.22.2-1.61.42.01.4
Number of licking bursts0.20.60.8-0.8-0.7-0.70.8-0.7-0.7-0.7-0.9-0.70.80.90.80.80.90.7-0.60.50.90.7
Context. condit. distance diff. score2.22.73.61.61.71.6-1.71.91.71.81.81.6-1.8-1.6-1.8-1.8-1.7-1.61.4-1.4-1.7-1.1
Locomotion velocity, session 10.00.00.20.10.10.20.00.1-0.10.10.40.1-0.00.0-0.0-0.0-0.1-0.20.10.2-0.4-0.1
Locomotion distance, session 10.50.72.4-1.0-1.0-0.70.7-0.7-0.8-0.7-0.7-1.10.80.80.80.80.60.6-1.5-0.60.10.2
Locomotion velocity, session 22.73.35.0-2.2-2.1-1.81.9-1.9-1.8-1.9-1.7-2.02.01.92.02.01.71.7-2.20.61.30.8
Locomotion distance, session 20.81.13.5-1.3-1.2-0.91.1-1.1-1.1-1.1-0.8-1.31.01.11.01.01.00.9-1.9-0.40.30.1
Locomotion velocity, session 30.10.11.00.20.20.3-0.40.40.30.40.40.2-0.3-0.3-0.3-0.3-0.3-0.3-0.2-1.0-0.4-0.3
Locomotion distance, session 30.00.00.00.10.10.1-0.10.1-0.10.10.10.1-0.1-0.0-0.1-0.1-0.1-0.1-0.2-0.1-0.1-0.0
Stereotopy head waving bouts, day 30.91.12.70.70.81.1-1.11.01.21.01.00.7-1.1-1.1-1.1-1.1-1.2-1.20.0-1.6-1.3-1.0
Stereotopy head waving duration, day 31.01.32.00.90.91.2-1.21.21.31.11.00.9-1.3-1.2-1.3-1.3-1.2-1.20.6-1.4-1.2-0.9
Locomotion velocity, session 70.30.33.30.00.30.3-0.40.50.30.50.50.2-0.5-0.5-0.5-0.5-0.2-0.3-0.3-1.8-0.4-0.2
Locomotion distance, session 70.10.11.1-0.2-0.00.00.1-0.0-0.1-0.00.3-0.2-0.1-0.0-0.1-0.10.10.0-0.8-1.0-0.5-0.3
Stereotopy head waving bouts, day 70.00.00.3-0.00.0-0.1-0.20.20.20.2-0.30.0-0.1-0.1-0.1-0.10.00.00.1-0.50.30.2
Stereotopy head waving duration, day 70.70.91.8-1.1-1.0-1.20.9-0.8-0.9-0.8-1.3-1.00.90.90.90.91.11.1-0.70.00.90.7
Locomotion velocity, session 80.91.11.5-0.8-1.0-1.11.2-1.1-1.2-1.1-0.9-1.11.11.21.11.11.11.1-1.01.10.40.2
Locomotion distance, session 80.30.41.40.20.40.6-0.60.70.50.70.70.4-0.7-0.6-0.6-0.6-0.7-0.60.1-1.2-0.8-0.6
Degree of sensitization distance0.10.10.8-0.3-0.2-0.10.1-0.10.0-0.10.0-0.3-0.00.00.00.00.20.1-0.6-0.9-0.3-0.1
Degree of sensitization stereotypy0.60.61.3-0.9-0.8-1.00.7-0.7-0.7-0.7-1.1-0.70.80.80.80.80.90.9-0.30.31.10.8
Conditioned locomotion1.61.82.6-1.4-1.4-1.51.6-1.4-1.6-1.5-1.1-1.31.41.51.41.41.51.5-1.21.10.80.7
Cocaine response after cond. corrected1.11.62.41.41.41.2-1.21.41.11.41.61.3-1.3-1.4-1.3-1.3-1.1-1.11.0-1.2-1.3-1.0
Cocaine response after cond. not corrected0.81.11.51.21.21.0-1.11.21.01.21.21.1-1.1-1.1-1.1-1.1-0.9-0.90.8-0.9-1.0-0.8
Cocaine response before conditioning0.91.11.9-1.0-1.1-1.00.9-1.1-0.8-1.1-1.4-1.01.11.11.01.00.90.9-0.70.91.30.9
Saline control response3.95.46.6-2.3-2.5-2.32.4-2.6-2.3-2.5-2.4-2.62.62.42.62.62.22.3-2.61.81.61.2
Bone: connectivity density2.74.37.2-2.3-2.3-2.22.0-2.1-2.1-2.1-2.5-2.52.12.02.12.12.12.1-2.70.51.41.4
Bone: cortical apparent density0.10.10.4-0.3-0.3-0.40.4-0.2-0.5-0.3-0.1-0.20.20.40.40.40.30.40.30.60.20.3
Bone: cortical area0.91.41.8-1.2-1.2-1.31.3-1.3-1.2-1.3-1.2-1.01.31.31.31.31.31.3-0.81.01.30.6
Bone: cortical porosity0.10.20.9-0.5-0.5-0.20.2-0.4-0.3-0.4-0.5-0.60.40.30.30.30.20.2-1.0-0.2-0.00.1
Bone: cortical porosity0.40.51.7-0.9-0.9-0.50.6-0.8-0.6-0.8-0.8-0.90.80.60.60.70.50.4-1.30.00.30.3
Bone: cortical thickness3.35.67.6-1.9-2.1-2.52.8-2.6-2.6-2.5-1.9-2.02.62.72.62.62.72.7-1.72.52.01.1
Bone: cortical thickness0.60.71.3-0.5-0.6-0.81.1-1.0-0.9-1.0-0.4-0.71.01.01.00.91.01.0-0.91.10.60.4
Bone: cortical tissue density0.10.20.6-0.4-0.4-0.50.6-0.4-0.7-0.4-0.3-0.40.40.60.50.50.50.60.20.80.30.3
Condit. Reinf. active minus inactive responses0.20.30.7-0.5-0.5-0.50.5-0.4-0.7-0.4-0.5-0.60.50.80.50.50.60.5-0.6-0.40.30.2
Condit. Reinf. active-inactive response ratio0.00.00.3-0.1-0.1-0.20.20.0-0.3-0.0-0.3-0.20.10.50.20.20.30.2-0.1-0.30.00.1
Condit. Reinf. active responses0.10.20.5-0.5-0.3-0.40.4-0.2-0.6-0.3-0.3-0.30.40.70.40.40.50.4-0.3-0.60.50.2
Condit. Reinf. inactive responses0.00.00.3-0.10.0-0.1-0.00.1-0.00.10.20.1-0.0-0.0-0.1-0.10.00.10.1-0.60.30.0
Incentive salience index mean0.40.50.9-0.9-0.8-0.70.7-0.5-0.8-0.6-0.6-0.80.70.90.70.70.80.7-0.8-0.60.40.2
Condit. Reinf. lever presses0.50.71.4-1.2-1.0-0.90.9-0.8-0.9-0.9-0.8-0.90.90.90.80.80.90.9-0.5-0.10.80.3
Condit. Reinf. active minus inactive responses0.00.10.20.10.10.3-0.30.10.30.2-0.40.0-0.1-0.1-0.1-0.1-0.3-0.40.4-0.00.3-0.0
Condit. Reinf. active-inactive response ratio0.40.61.80.60.70.9-1.00.81.00.80.30.8-0.7-0.8-0.7-0.7-1.0-1.11.3-0.60.1-0.2
Condit. Reinf. active responses0.20.21.0-0.5-0.6-0.30.2-0.5-0.3-0.4-1.0-0.70.50.40.50.40.40.2-0.70.00.40.2
Condit. Reinf. inactive responses0.60.93.9-0.9-0.9-0.90.8-0.9-0.9-0.9-1.0-1.20.90.80.80.81.00.9-2.00.10.10.3
Condit. Reinf. lever presses2.33.35.3-1.9-1.9-1.81.8-1.9-1.7-1.9-2.3-1.92.02.02.02.01.81.6-1.61.21.81.0
Condit. Reinf. lever reinforcers received0.40.61.7-0.8-0.9-0.60.6-0.8-0.6-0.8-1.3-1.00.80.70.80.80.60.5-0.90.40.70.3
Conditioned reinforcement - actives0.00.11.00.0-0.0-0.10.0-0.10.0-0.1-0.30.20.1-0.10.10.10.0-0.00.61.01.00.5
Conditioned reinforcement - inactives1.13.15.12.22.01.8-1.92.01.92.01.52.1-2.0-1.7-1.9-1.9-1.7-1.82.3-0.5-0.2-0.2
Conditioned locomotion6.79.912.63.53.43.4-3.43.33.43.33.23.5-3.3-3.4-3.3-3.3-3.3-3.33.4-1.5-1.7-1.3
Patch foraging indifference point 0 sec0.00.10.20.10.10.3-0.40.10.50.1-0.00.0-0.2-0.4-0.3-0.3-0.3-0.3-0.2-0.1-0.10.0
Patch foraging indifference point AUC1.43.44.1-2.0-2.0-1.92.0-2.0-2.0-2.0-2.0-1.81.91.82.02.01.91.8-1.01.91.81.2
Delay disc. indifference point, 0s delay0.80.93.10.50.71.0-0.90.91.00.91.00.6-1.0-0.9-1.0-0.9-1.0-1.0-0.5-1.5-1.7-0.6
Delay disc. indifference point, 16s delay0.40.61.00.60.70.9-1.00.80.90.80.60.8-0.9-0.8-0.9-0.8-1.0-1.00.5-1.0-0.3-0.1
Delay disc. indifference point, 2s delay0.10.20.40.30.40.6-0.50.50.50.40.30.3-0.3-0.4-0.3-0.4-0.5-0.6-0.1-0.6-0.4-0.0
Delay disc. indifference point, 24s delay0.10.10.50.30.30.3-0.30.20.30.30.60.3-0.4-0.3-0.4-0.3-0.4-0.2-0.2-0.2-0.7-0.2
Delay disc. indifference point, 4s delay0.30.31.10.30.40.5-0.50.40.50.50.50.2-0.4-0.4-0.4-0.5-0.5-0.5-0.7-0.9-1.0-0.2
Delay disc. indifference point, 8s delay0.10.21.10.20.20.4-0.20.30.30.30.40.0-0.4-0.3-0.4-0.4-0.3-0.4-0.6-0.7-1.0-0.2
Indifference point function ln k4.212.816.13.83.84.0-3.83.63.93.74.03.6-3.5-3.8-3.7-3.7-3.9-3.82.4-2.9-3.1-2.4
Indifference point function log k4.212.816.13.83.84.0-3.83.63.93.74.03.6-3.5-3.8-3.7-3.7-3.9-3.82.4-2.9-3.1-2.4
Patch foraging total patch changes 0 sec0.00.00.20.10.10.3-0.2-0.00.40.00.10.0-0.1-0.3-0.2-0.2-0.3-0.3-0.10.2-0.2-0.1
Patch foraging total patch changes 12 sec4.76.37.8-2.8-2.8-2.62.6-2.8-2.5-2.7-2.7-2.82.62.52.72.72.62.5-2.31.62.01.4
Patch foraging total patch changes 18 sec0.40.91.3-1.1-1.1-0.90.9-1.0-1.0-1.0-1.2-1.11.00.81.11.10.90.8-1.10.60.91.0
Patch foraging total patch changes 24 sec0.72.63.8-1.6-1.7-1.61.7-1.8-1.6-1.8-1.7-1.71.61.51.71.81.61.5-1.11.91.20.9
Patch foraging total patch changes 6 sec1.11.92.6-1.3-1.4-1.51.4-1.5-1.3-1.5-1.5-1.61.41.41.61.61.51.5-1.60.70.90.7
Patch foraging time to switch 0 sec0.93.45.1-2.3-2.0-2.21.8-1.7-1.9-1.7-2.1-2.11.62.01.61.62.12.1-2.0-0.41.51.3
Patch foraging water rate 0 sec1.97.210.33.23.03.0-2.72.72.92.73.03.1-2.6-2.8-2.7-2.7-2.7-2.83.1-0.3-2.0-1.7
Patch foraging water rate 12 sec3.715.021.24.64.34.2-3.93.94.24.04.44.2-3.9-4.0-3.8-4.0-4.0-4.03.4-1.4-3.5-2.6
Patch foraging water rate 18 sec2.24.86.82.62.52.5-2.32.32.42.32.52.3-2.2-2.1-2.0-2.0-2.3-2.31.7-1.2-2.0-1.6
Patch foraging water rate 24 sec5.27.49.73.13.02.9-2.72.92.82.83.13.0-3.0-2.8-2.8-2.8-2.7-2.72.9-0.7-2.5-1.7
Patch foraging water rate 6 sec4.76.910.33.23.03.1-2.62.62.82.73.12.9-2.5-2.5-2.5-2.5-2.8-2.92.1-0.7-2.5-1.9
Seeking ratio, delayed vs. immediate footshock0.10.10.80.20.20.2-0.30.30.20.30.10.1-0.4-0.2-0.4-0.3-0.1-0.1-0.5-0.90.00.4
Distance traveled before self-admin0.30.71.4-1.2-1.0-0.80.7-0.9-0.7-0.8-1.1-0.91.00.60.90.80.70.7-0.80.30.80.6
Distance traveled after self-admin0.20.30.5-0.7-0.7-0.60.5-0.7-0.5-0.6-0.7-0.60.60.30.50.50.50.50.10.60.60.2
Extensor digitorum longus weight7.730.937.8-6.1-6.0-6.16.2-6.0-6.1-6.0-5.4-5.75.95.95.95.95.96.0-4.73.34.22.7
Bone: elastic displacement0.70.92.01.41.30.9-0.70.90.90.91.41.2-0.8-0.8-0.9-0.9-0.8-0.71.30.3-0.9-0.6
Bone: elastic work0.91.11.8-0.9-0.9-1.01.3-1.3-1.1-1.2-0.6-0.91.31.31.21.21.11.1-0.81.30.50.3
Bone: endosteal estimation0.71.73.60.70.91.5-1.51.31.61.31.00.9-1.3-1.5-1.4-1.5-1.5-1.60.5-1.9-1.2-0.7
Bone: endosteal perimeter0.81.93.90.91.01.5-1.71.41.71.40.81.1-1.4-1.6-1.5-1.5-1.6-1.70.8-2.0-0.9-0.7
Epididymis fat weight2.412.215.53.43.53.8-3.93.73.93.73.33.7-3.6-3.9-3.7-3.7-3.8-3.83.7-2.2-2.3-1.8
Delta time in closed arm before/after self-admin0.20.20.9-0.2-0.2-0.50.6-0.3-0.5-0.30.1-0.50.40.40.40.50.60.6-1.0-0.0-0.4-0.1
Delta time in open arm before/after self-admin0.20.30.7-0.5-0.5-0.60.5-0.5-0.5-0.5-0.8-0.40.30.60.30.30.50.50.50.70.90.4
Diff in mean of infusions in LGA sessions0.50.91.5-0.8-0.8-1.11.0-0.9-1.1-0.9-1.0-0.91.01.11.21.01.11.1-0.40.90.90.4
Delay discount exponential model param0.10.10.50.0-0.0-0.30.2-0.1-0.2-0.2-0.20.00.20.20.20.20.30.30.70.70.6-0.1
Extinction: sum of active levers before priming2.23.34.5-2.1-2.0-1.91.7-1.9-1.7-1.9-2.0-2.02.01.92.01.81.81.8-1.90.71.71.2
Active lever presses in extinction session 63.53.54.5-2.0-2.0-2.12.0-1.9-2.0-2.0-2.1-1.82.01.91.91.82.02.0-0.91.81.81.2
Bone: final force2.33.84.9-2.2-2.2-2.02.1-2.1-2.0-2.1-2.0-2.12.02.12.22.11.91.8-1.81.41.60.9
Bone: final moment2.23.54.5-2.1-2.1-1.92.0-2.1-1.9-2.0-2.0-2.02.02.12.12.01.81.7-1.81.31.50.9
Food consumed during 24 hour testing period0.10.11.00.1-0.0-0.10.1-0.2-0.0-0.2-0.30.10.20.20.20.20.10.10.71.00.6-0.0
Glucose2.53.97.81.71.82.0-2.22.12.22.11.81.6-2.2-2.0-2.2-2.1-2.1-2.00.7-2.8-1.9-1.3
Heart weight1.22.07.91.01.21.3-1.41.41.31.41.30.8-1.5-1.4-1.4-1.4-1.3-1.2-0.4-2.8-2.1-0.9
Delay discount hyperbolic model param0.10.10.50.0-0.1-0.30.3-0.2-0.3-0.2-0.2-0.00.20.20.20.20.30.40.70.70.6-0.1
Intermittent access intake day 1-15 change0.31.74.21.51.41.2-1.31.41.31.41.11.5-1.4-1.3-1.4-1.3-1.3-1.22.1-0.1-0.2-0.2
Intermittent access intake escalation0.21.34.21.31.31.0-1.21.21.11.21.01.4-1.3-1.1-1.2-1.2-1.1-1.02.10.1-0.0-0.1
Intermittent access intake escalation 20.81.44.31.21.21.1-1.21.21.21.21.01.4-1.3-1.2-1.2-1.2-1.2-1.12.10.0-0.3-0.4
Intermitt. access day 1 inactive lever presses0.00.10.70.40.40.2-0.30.40.20.40.30.4-0.5-0.1-0.4-0.4-0.2-0.20.80.0-0.1-0.1
Intermitt. access day 15 inactive lever presses0.31.52.71.51.51.2-1.31.41.21.41.01.5-1.4-1.0-1.2-1.2-1.0-1.11.6-1.10.1-0.1
Intermitt. access escalation Index1.44.46.02.12.12.5-2.32.12.42.12.22.1-2.0-2.2-2.1-2.1-2.3-2.41.1-2.2-2.0-1.4
Intermittent access day 1 total infusions0.92.67.51.61.71.6-1.81.81.61.81.31.5-1.7-1.7-1.7-1.7-1.5-1.50.5-2.7-0.9-0.4
Intermittent access day 15 total infusions2.25.47.52.72.72.4-2.62.62.42.62.12.7-2.5-2.4-2.4-2.4-2.3-2.32.5-1.9-0.6-0.5
Intermittent access terminal intake (last 3 days)2.44.25.72.32.42.0-2.32.42.12.31.82.3-2.3-2.1-2.2-2.2-2.0-1.92.1-2.0-0.6-0.4
Intermittent access total infusions2.42.84.81.92.01.7-1.91.91.71.91.41.8-1.8-1.7-1.7-1.7-1.6-1.61.1-2.2-0.4-0.3
Intermittent access day 1 locomotion1.01.84.61.41.51.3-1.51.61.31.51.21.3-1.5-1.5-1.4-1.4-1.2-1.20.6-2.1-0.7-0.2
Intermittent access day 15 total locomotion1.14.25.72.42.42.0-2.42.42.22.31.72.3-2.2-2.2-2.1-2.1-2.1-2.02.1-1.8-0.2-0.0
Intermittent access total locomotion5.26.38.52.72.82.6-2.92.92.72.82.12.7-2.7-2.7-2.6-2.6-2.6-2.52.2-2.7-0.6-0.4
Intermittent access standard deviation0.31.63.01.61.61.2-1.31.51.21.41.31.5-1.5-1.2-1.3-1.3-1.1-1.11.7-0.3-0.7-0.4
Left kidney weight0.54.05.31.51.82.0-2.12.02.22.02.12.0-2.1-2.3-2.1-2.1-2.1-2.11.9-2.2-1.5-1.5
Right kidney weight0.32.22.91.31.41.6-1.51.41.61.51.61.6-1.6-1.6-1.5-1.5-1.6-1.61.7-0.9-1.0-1.2
Cocaine induced anxiety0.00.10.4-0.3-0.3-0.30.3-0.3-0.2-0.2-0.3-0.10.20.30.10.10.30.30.30.10.60.2
Post-drug Anxiety0.80.91.2-1.1-1.1-1.00.9-1.1-0.9-1.0-1.1-0.91.01.00.90.90.90.9-0.31.11.10.4
Baseline Anxiety0.20.30.9-0.5-0.6-0.40.5-0.7-0.4-0.7-0.5-0.60.60.40.60.70.40.4-0.60.9-0.1-0.2
Tail length0.21.22.0-1.0-1.1-1.21.4-1.4-1.3-1.3-0.7-1.01.31.11.21.21.11.2-0.51.40.3-0.1
Length with tail1.77.49.7-2.8-2.9-2.93.1-3.1-3.0-3.1-2.5-2.73.12.83.03.02.82.8-2.22.71.70.9
Length without tail1.16.07.5-2.3-2.5-2.52.7-2.7-2.6-2.7-2.3-2.52.72.62.72.72.42.4-2.22.71.51.0
Times rat made contact with spout0.50.51.9-0.8-0.8-0.60.7-0.8-0.7-0.7-0.7-0.90.80.70.80.80.60.6-1.40.20.40.5
Lifetime Intake1.62.03.91.71.71.4-1.61.61.41.61.21.5-1.5-1.5-1.4-1.4-1.3-1.30.7-2.0-0.5-0.3
Liver weight, left1.01.72.91.31.31.3-1.21.41.31.41.71.4-1.3-1.4-1.3-1.3-1.2-1.21.1-0.7-1.3-0.8
Liver weight, right2.34.16.12.32.22.1-2.02.22.02.22.52.0-2.2-2.0-2.1-2.1-2.0-1.91.1-1.5-2.1-1.3
Locomotor activity2.03.15.12.32.12.1-1.81.91.91.92.21.9-1.6-1.6-1.6-1.5-1.9-1.91.5-0.4-1.6-1.0
Locomotor testing distance1.74.16.72.62.42.4-2.02.02.12.12.52.2-1.8-2.1-1.8-1.8-2.2-2.21.4-0.5-2.1-1.3
Locomotor testing rearing1.03.66.02.52.22.1-2.02.02.02.02.21.9-1.8-2.0-1.8-1.8-2.0-2.01.0-0.8-2.1-1.2
Locomotion in novel chamber5.37.18.82.82.83.0-2.92.82.92.82.62.8-2.8-2.7-2.8-2.8-2.9-3.02.7-1.6-1.7-1.2
Locomotion in novel chamber post-restriction1.34.05.12.12.22.2-2.32.12.32.21.92.2-1.9-2.0-2.1-2.0-2.2-2.22.0-1.6-1.1-0.9
Fecal boli incidents, locomotor time 10.10.20.8-0.2-0.1-0.30.1-0.1-0.2-0.0-0.40.10.2-0.00.20.00.20.20.50.80.90.9
Change in fecal boli incidents, locomotor task0.10.10.40.00.00.3-0.10.00.20.00.2-0.2-0.2-0.1-0.2-0.1-0.3-0.3-0.6-0.6-0.6-0.3
Time >=10cm from walls, locomotor time 10.50.62.40.50.70.7-0.91.00.80.90.30.6-0.9-0.7-0.9-0.9-0.7-0.70.6-1.5-0.10.4
Bouts of movement, locomotor time 11.31.73.1-1.4-1.4-1.51.4-1.2-1.6-1.3-1.5-1.31.21.41.11.11.41.4-0.21.81.01.1
Total resting periods, locomotor time 11.01.21.8-1.2-1.2-1.21.1-1.0-1.3-1.0-1.4-1.11.01.10.90.91.11.1-0.21.31.01.0
Rest time, locomotor task time 11.21.93.41.51.51.5-1.51.41.51.51.31.6-1.3-1.5-1.3-1.4-1.5-1.51.8-0.2-0.9-0.7
Distance moved, locomotor task time 10.10.31.3-0.5-0.4-0.50.4-0.4-0.4-0.4-0.5-0.70.40.60.40.50.50.5-1.1-1.00.10.1
Vertical activity count, locomotor time 10.10.81.31.11.10.9-1.01.10.91.01.01.0-1.0-0.9-1.0-1.0-0.8-0.80.4-0.9-0.5-0.3
Time >=10cm from walls, locomotor time 20.00.00.1-0.3-0.2-0.00.0-0.00.0-0.1-0.3-0.1-0.10.1-0.10.0-0.1-0.10.30.10.10.3
Bouts of movement, locomotor time 20.20.81.2-1.0-1.0-1.00.9-0.9-1.1-0.9-0.9-0.90.70.80.60.71.01.0-0.70.70.70.8
Total resting periods, locomotor time 20.10.40.6-0.8-0.7-0.70.6-0.6-0.8-0.6-0.7-0.60.40.60.30.40.70.7-0.50.30.50.6
Rest time, locomotor task time 21.83.13.61.71.81.8-1.81.81.81.91.81.9-1.9-1.8-1.8-1.8-1.7-1.71.8-1.5-1.5-1.1
Distance moved, locomotor task time 21.11.52.0-1.1-1.2-1.31.4-1.3-1.3-1.3-1.3-1.31.21.41.31.41.31.3-1.01.00.80.6
Vertical activity count, locomotor time 20.00.11.30.40.3-0.00.20.0-0.1-0.00.30.2-0.00.2-0.00.10.10.10.41.10.10.0
Light reinforcement 10.00.20.50.50.40.5-0.50.30.50.30.40.4-0.3-0.7-0.2-0.3-0.5-0.50.1-0.1-0.3-0.2
Light reinforcement 20.40.91.41.01.01.1-1.21.01.11.00.71.2-0.9-1.1-0.9-1.0-1.1-1.21.2-0.30.0-0.1
Bone: marrow area0.81.94.20.70.91.5-1.61.41.61.41.11.0-1.4-1.6-1.5-1.5-1.6-1.70.5-2.0-1.4-0.8
Bone: maximum diameter0.10.30.6-0.6-0.6-0.50.4-0.5-0.4-0.5-0.8-0.40.50.40.40.40.50.40.10.70.80.2
Bone: maximum force3.16.08.5-2.9-2.8-2.52.5-2.6-2.4-2.6-2.8-2.72.62.62.72.62.42.3-2.40.92.01.3
Bone: maximum moment2.95.57.6-2.8-2.7-2.42.3-2.5-2.3-2.5-2.7-2.62.42.52.52.52.32.2-2.30.91.91.3
Mean time between licks in bursts0.00.31.0-0.3-0.4-0.40.6-0.5-0.5-0.5-0.2-0.60.50.50.60.50.50.5-1.00.7-0.2-0.0
Mean num. licks in bursts0.10.40.70.60.60.6-0.70.60.60.60.70.4-0.6-0.7-0.6-0.6-0.8-0.60.0-0.6-0.8-0.5
Cd content in liver1.21.32.11.11.21.3-1.41.21.31.20.91.2-1.1-1.2-1.1-1.2-1.4-1.31.4-0.6-0.00.1
Co content in liver1.72.03.71.61.61.6-1.21.31.31.31.91.6-1.4-1.3-1.4-1.4-1.4-1.51.5-0.1-1.5-1.1
Cu content in liver0.10.10.6-0.10.00.1-0.1-0.10.10.0-0.1-0.10.10.10.10.1-0.1-0.1-0.8-0.60.30.2
Fe content in liver0.10.20.6-0.2-0.3-0.40.4-0.5-0.4-0.5-0.3-0.30.50.30.50.40.50.4-0.30.80.30.4
K content in liver0.50.51.7-0.8-0.8-0.70.7-0.7-0.7-0.7-0.6-0.90.70.70.70.70.70.7-1.3-0.30.20.2
Mg content in liver0.40.41.00.50.60.7-0.60.60.60.60.60.4-0.6-0.5-0.6-0.6-0.6-0.6-0.4-1.0-0.8-0.4
Mn content in liver4.14.66.0-2.1-2.2-2.42.3-2.1-2.4-2.2-2.4-2.12.22.32.22.22.42.4-1.31.71.91.3
Na content in liver0.30.31.2-0.5-0.6-0.30.6-0.7-0.5-0.7-0.6-0.40.70.50.70.70.50.30.11.10.50.2
Rb content in liver1.92.23.01.61.61.7-1.71.51.71.61.51.4-1.5-1.6-1.5-1.5-1.7-1.60.4-1.4-1.4-0.7
Se content in liver0.10.10.10.40.30.2-0.30.30.30.3-0.10.3-0.2-0.2-0.2-0.2-0.3-0.20.4-0.10.30.1
Sr content in liver2.62.22.9-1.4-1.5-1.71.7-1.6-1.7-1.7-1.5-1.41.61.31.61.51.71.7-0.81.61.30.8
Zn content in liver0.20.30.9-0.6-0.5-0.40.5-0.6-0.4-0.6-0.4-0.60.50.60.50.50.40.4-1.0-0.00.30.2
Bone: minimum diameter0.61.14.70.50.71.1-1.31.01.21.00.60.6-1.0-1.1-1.1-1.1-1.1-1.2-0.1-2.2-0.8-0.4
Time in familiar zone, hab. session 10.20.21.00.30.40.5-0.50.40.50.40.30.3-0.3-0.4-0.3-0.3-0.4-0.50.4-1.0-0.1-0.2
Time in novel zone, hab. session 10.30.30.60.80.60.5-0.40.50.40.50.70.5-0.6-0.5-0.6-0.6-0.4-0.40.10.5-0.8-0.5
Total zone transitions, hab. session 10.81.11.5-1.2-1.2-0.91.1-1.1-1.1-1.1-1.0-1.11.11.21.11.10.90.9-1.10.11.00.6
Total locomotion distance, hab. session 10.40.51.60.20.40.7-0.70.70.70.70.70.6-0.7-0.7-0.8-0.8-0.8-0.80.8-1.3-0.7-0.5
Locomotion velocity, hab. session 10.10.10.7-0.3-0.10.2-0.20.10.20.10.20.1-0.2-0.2-0.2-0.2-0.3-0.30.3-0.8-0.2-0.2
Time in familiar zone, hab. session 20.00.00.10.40.3-0.00.10.0-0.2-0.00.30.0-0.00.1-0.0-0.00.10.2-0.20.3-0.4-0.1
Time in novel zone, hab. session 20.10.10.2-0.5-0.4-0.10.0-0.20.1-0.1-0.4-0.30.20.10.10.10.1-0.0-0.4-0.40.10.0
Total zone transitions, hab. session 21.41.84.8-1.8-1.7-1.11.1-1.3-1.2-1.3-1.6-1.91.31.31.31.31.00.9-2.2-0.70.50.7
Total locomotion distance, hab. session 20.20.22.6-0.4-0.20.2-0.30.20.20.20.0-0.3-0.2-0.2-0.2-0.2-0.4-0.4-0.7-1.6-0.7-0.2
Locomotion velocity, hab. session 20.20.33.0-0.3-0.00.4-0.50.40.40.30.2-0.1-0.4-0.4-0.4-0.4-0.5-0.6-0.4-1.7-0.6-0.2
Novel to familiar place preference ratio1.01.32.3-1.4-1.3-1.41.1-1.1-1.1-1.1-1.5-1.11.10.91.11.11.31.4-0.50.71.30.8
Novelty place preference0.50.61.3-1.0-0.9-1.00.6-0.7-0.7-0.7-1.1-0.70.70.50.70.70.90.9-0.30.31.00.6
Time in novel zone, NPP test0.30.40.9-0.8-0.7-0.90.5-0.6-0.6-0.6-0.9-0.60.60.40.60.60.70.8-0.20.30.80.5
Total zone transitions, NPP test2.02.94.9-2.2-2.1-1.61.7-1.9-1.7-1.9-1.9-2.11.81.81.81.81.51.3-2.00.41.20.8
Total locomotion distance, NPP test0.10.10.7-0.6-0.40.10.1-0.1-0.0-0.2-0.0-0.40.10.10.10.1-0.1-0.2-0.5-0.9-0.3-0.3
Locomotion velocity, NPP test0.10.10.6-0.7-0.5-0.00.2-0.3-0.1-0.3-0.1-0.50.30.20.20.2-0.0-0.1-0.5-0.7-0.1-0.1
Intraocular pressure0.81.46.31.31.30.7-0.91.30.91.21.01.5-1.4-1.1-1.4-1.4-0.6-0.52.50.5-0.2-0.1
Delta distance traveled before/after self-admin0.10.10.50.50.40.3-0.20.20.20.20.50.3-0.4-0.4-0.3-0.3-0.2-0.20.70.3-0.4-0.7
Delta ambulatory time before/after self-admin0.00.10.30.30.20.1-0.0-0.00.10.00.30.1-0.1-0.3-0.1-0.1-0.0-0.00.40.5-0.2-0.4
Parametrial fat weight3.78.611.62.72.92.9-3.13.23.03.12.93.0-3.3-3.2-3.4-3.3-2.7-2.82.7-3.0-2.3-1.7
Pavlov. Cond. lever latency0.20.30.60.80.70.5-0.50.60.50.60.50.6-0.6-0.5-0.5-0.5-0.5-0.40.70.2-0.3-0.2
Pavlov. Cond. magazine entry latency0.20.20.9-0.9-0.8-0.30.3-0.4-0.3-0.4-0.7-0.70.40.40.40.40.20.1-0.6-0.70.30.1
Pavlov. Cond. change in total contacts0.10.10.5-0.7-0.5-0.20.2-0.3-0.3-0.3-0.7-0.30.30.40.30.30.20.10.2-0.50.70.3
Pavlov. Cond. index score0.10.20.5-0.7-0.6-0.30.4-0.4-0.3-0.5-0.6-0.50.50.40.40.40.20.2-0.2-0.00.40.2
Pavlov. Cond. latency score0.10.10.4-0.6-0.5-0.10.2-0.3-0.1-0.3-0.4-0.40.30.20.30.30.10.0-0.3-0.30.20.0
Pavlov. Cond. lever contacts0.10.10.3-0.5-0.4-0.10.2-0.3-0.1-0.3-0.3-0.40.30.20.20.20.10.1-0.5-0.50.0-0.0
Pavlov. Cond. magazine entry number0.20.30.60.80.70.4-0.50.60.50.60.80.5-0.6-0.6-0.6-0.6-0.4-0.30.1-0.4-0.7-0.3
Pavlov. Cond. intertrial magazine entries0.30.31.50.90.80.5-0.50.50.50.50.50.8-0.4-0.3-0.4-0.4-0.4-0.41.2-0.10.4-0.0
Pavlov. Cond. lever-magazine prob. diff.0.30.30.9-1.0-0.9-0.50.5-0.6-0.5-0.6-0.8-0.70.60.60.60.60.40.3-0.4-0.10.60.2
Pavlov. Cond. response bias0.20.20.4-0.7-0.6-0.30.4-0.5-0.4-0.5-0.6-0.40.50.50.50.50.30.3-0.00.20.60.2
Pavlov. Cond. lever latency0.70.91.41.01.01.0-1.01.00.91.01.10.8-1.0-1.1-1.0-1.0-1.0-0.90.4-0.9-1.2-0.5
Pavlov. Cond. magazine entry latency4.66.58.2-2.8-2.7-2.72.6-2.7-2.7-2.6-2.9-2.72.62.72.72.72.72.6-2.61.22.21.5
Pavlov. Cond. change in total contacts1.22.95.1-1.9-1.9-1.71.6-1.8-1.7-1.8-2.3-1.71.81.71.81.81.71.5-1.00.92.11.2
Pavlov. Cond. index score2.64.15.6-2.2-2.2-2.12.0-2.1-2.1-2.1-2.4-2.02.12.22.22.22.11.9-1.71.12.11.2
Pavlov. Cond. latency score2.23.54.7-2.1-2.0-1.91.9-2.0-1.9-1.9-2.2-1.92.02.02.02.01.91.8-1.41.02.01.2
Pavlov. Cond. lever contacts0.71.01.5-1.0-1.0-1.01.0-1.0-1.0-1.0-1.2-0.91.01.11.11.11.00.9-0.50.91.20.6
Pavlov. Cond. magazine entry number7.910.213.43.43.43.4-3.33.43.33.33.73.4-3.4-3.4-3.4-3.4-3.3-3.22.9-1.9-2.8-2.0
Pavlov. Cond. intertrial magazine entries0.81.72.21.31.31.5-1.41.31.41.31.31.4-1.4-1.4-1.4-1.4-1.5-1.51.4-0.7-0.8-0.6
Pavlov. Cond. lever-magazine prob. diff.3.24.96.7-2.4-2.4-2.32.3-2.3-2.3-2.3-2.6-2.32.32.42.42.42.32.1-1.91.22.21.3
Pavlov. Cond. response bias2.43.34.7-1.9-2.0-1.91.9-1.9-1.8-1.9-2.2-1.91.92.01.91.91.91.8-1.51.11.81.0
Time in closed arm before self-admin0.20.30.60.30.40.7-0.70.50.60.50.20.5-0.6-0.7-0.8-0.7-0.8-0.80.3-0.3-0.20.1
Time in closed arm after self-admin0.10.20.30.40.50.4-0.40.50.30.40.50.4-0.4-0.5-0.6-0.5-0.3-0.3-0.1-0.5-0.3-0.2
Time in open arm before self-admin0.30.42.00.70.70.5-0.30.60.40.51.10.4-0.4-0.4-0.2-0.3-0.3-0.3-0.3-0.8-1.4-0.9
Time in open arm after self-admin0.10.10.2-0.1-0.1-0.30.3-0.1-0.3-0.2-0.1-0.20.10.40.20.20.40.40.10.1-0.4-0.3
Bone: periosteal estimation0.00.00.2-0.4-0.20.0-0.1-0.10.1-0.0-0.2-0.10.0-0.1-0.0-0.1-0.0-0.1-0.1-0.40.20.0
Bone: periosteal perimeter0.10.20.6-0.6-0.6-0.40.3-0.5-0.3-0.5-0.8-0.50.50.40.40.40.40.3-0.5-0.10.40.1
Bone: post-yield work0.81.44.6-1.9-1.5-0.90.5-0.8-0.8-0.8-1.7-1.50.80.80.90.90.80.6-1.6-2.10.90.8
Progressive ratio test 1 active lever presses0.00.10.30.50.50.1-0.20.30.10.30.20.4-0.2-0.2-0.2-0.30.0-0.00.2-0.40.20.2
Progressive ratio test 1 breakpoint0.00.10.20.40.50.0-0.10.20.00.20.10.3-0.1-0.1-0.2-0.20.10.10.1-0.30.30.3
Progressive ratio test 1 inactive lever presses0.00.00.20.30.30.1-0.10.20.10.20.00.2-0.2-0.1-0.2-0.2-0.0-0.10.30.10.20.4
Progressive ratio test 2 active lever presses1.21.72.91.71.71.3-1.51.51.41.51.11.6-1.4-1.4-1.4-1.4-1.2-1.21.3-1.1-0.1-0.1
Progressive ratio test 2 breakpoint1.31.72.91.71.71.2-1.41.51.31.51.11.5-1.4-1.3-1.4-1.4-1.2-1.11.3-1.0-0.1-0.1
Progressive ratio test 2 inactive lever presses2.78.611.23.33.33.1-3.33.33.13.22.73.2-3.2-3.1-3.1-3.2-2.9-3.02.9-2.1-1.3-0.7
Incentive Sensitization - Responses0.00.10.4-0.1-0.0-0.20.0-0.0-0.1-0.1-0.4-0.10.10.10.10.10.20.2-0.4-0.50.70.4
Incentive Sensitization - Breakpoint0.00.10.40.10.20.0-0.20.20.10.2-0.20.1-0.1-0.1-0.1-0.1-0.0-0.0-0.2-0.60.50.3
Sum of active levers in priming session hrs 5-62.12.07.2-0.8-1.0-1.31.3-1.2-1.2-1.2-1.4-0.61.31.21.51.31.31.30.92.72.41.2
Progressive ratio0.41.33.0-1.5-1.3-1.10.9-0.9-1.0-0.9-1.4-1.51.01.10.90.91.01.0-1.7-1.10.50.9
Food seeking constrained by brief footshock0.10.10.2-0.2-0.3-0.30.4-0.3-0.3-0.3-0.3-0.30.40.30.40.40.40.4-0.40.10.50.3
Seeking ratio, punishment vs. effort0.71.63.01.71.51.4-1.11.21.31.21.71.5-1.2-1.3-1.1-1.1-1.3-1.31.30.3-1.0-1.1
Retroperitoneal fat weight9.643.150.96.86.97.1-7.16.97.16.96.76.8-6.8-6.9-6.9-6.9-6.9-6.95.7-5.1-5.3-4.0
Reaction time number correct0.10.30.8-0.4-0.5-0.40.6-0.7-0.4-0.6-0.4-0.30.80.50.70.70.50.4-0.20.90.3-0.1
Reaction time mean minus median0.85.27.2-2.5-2.4-2.62.4-2.3-2.7-2.3-2.6-2.32.22.52.12.12.52.5-1.31.72.21.8
Reaction time mean minus median AUC0.42.94.4-1.7-1.7-1.91.9-1.7-2.1-1.7-1.7-1.51.61.81.61.61.91.9-0.81.61.61.5
Reaction time num false alarms0.30.41.40.80.80.6-0.50.50.70.51.20.7-0.5-0.5-0.5-0.5-0.5-0.50.6-0.5-0.9-0.8
Reaction time num false alarms AUC0.00.10.30.10.1-0.10.3-0.1-0.1-0.20.50.00.10.30.20.20.30.3-0.0-0.2-0.4-0.4
Reaction time trials correct on left0.10.30.8-0.4-0.5-0.40.6-0.7-0.4-0.6-0.4-0.30.80.50.70.70.50.4-0.20.90.3-0.1
Reaction time trials on left0.10.41.1-0.5-0.6-0.60.7-0.8-0.5-0.7-0.5-0.40.90.60.80.80.60.5-0.31.00.4-0.0
Reaction time mean0.10.10.4-0.4-0.3-0.30.3-0.2-0.4-0.2-0.4-0.20.00.3-0.00.00.30.30.60.30.60.7
Reaction time mean AUC0.00.10.5-0.4-0.3-0.20.2-0.1-0.3-0.1-0.4-0.2-0.10.2-0.1-0.10.20.20.60.10.50.7
Median of all reaction times0.10.20.90.20.30.4-0.40.50.30.40.20.4-0.6-0.3-0.6-0.6-0.4-0.40.9-0.3-0.00.2
Reaction time omissions1.93.24.8-1.8-1.8-2.12.0-1.8-2.1-1.8-1.8-1.71.71.91.61.62.22.2-1.11.21.51.1
Reaction time false alarm rate0.20.30.90.60.70.4-0.30.50.30.41.00.5-0.6-0.2-0.5-0.5-0.2-0.10.3-0.7-0.7-0.5
Reaction time premature initiation rate1.92.93.8-1.6-1.7-1.81.9-1.9-1.9-1.9-1.5-2.01.91.71.81.91.71.8-1.71.60.50.8
Reaction time premature initiations1.64.86.9-2.0-2.2-2.22.4-2.5-2.3-2.4-2.0-2.32.62.22.52.52.22.2-1.92.41.00.9
Std. dev. reaction times0.51.62.4-1.4-1.4-1.51.4-1.2-1.6-1.2-1.4-1.21.01.40.91.01.51.4-0.31.11.21.2
Reaction time trials completed0.10.41.1-0.5-0.6-0.60.7-0.8-0.5-0.7-0.5-0.40.90.60.80.80.60.5-0.31.00.4-0.0
Reaction time trials AUC0.10.20.7-0.3-0.4-0.40.5-0.6-0.3-0.5-0.3-0.30.70.40.60.60.40.4-0.20.80.2-0.1
Run reversals in cocaine runway, females0.40.53.1-0.7-0.6-0.50.5-0.5-0.6-0.5-0.3-0.70.50.60.50.60.50.5-1.8-1.2-0.20.1
Run reversals in cocaine runway, males0.30.41.41.00.80.3-0.30.60.40.60.90.9-0.5-0.4-0.4-0.4-0.2-0.21.20.6-0.1-0.4
Latency to leave start box in cocaine runway0.00.10.8-0.10.00.1-0.20.20.10.2-0.1-0.1-0.2-0.1-0.2-0.1-0.1-0.1-0.2-0.90.00.0
Latency to leave start box in cocaine runway, F0.10.10.9-0.10.00.1-0.10.10.10.1-0.0-0.1-0.1-0.0-0.1-0.0-0.1-0.1-0.4-1.0-0.2-0.1
Latency to leave start box in cocaine runway, M0.10.10.4-0.3-0.3-0.30.3-0.3-0.3-0.3-0.4-0.30.20.30.20.30.40.4-0.00.20.60.3
Std. dev. time between licks in bursts0.10.10.70.40.40.2-0.00.20.30.20.80.2-0.2-0.2-0.2-0.3-0.1-0.1-0.10.2-0.8-0.5
Total sessions with >9 infusions0.10.10.8-0.1-0.1-0.20.1-0.1-0.2-0.2-0.3-0.30.30.20.30.20.30.2-0.8-0.90.30.4
Short access day 1 total inactive lever presses1.42.83.81.81.81.9-1.91.71.91.71.71.7-1.6-1.8-1.5-1.6-1.9-1.91.2-1.3-0.9-0.8
Short access day 10 total inactive lever presses0.10.40.70.80.80.6-0.50.70.50.80.80.7-0.8-0.5-0.7-0.6-0.4-0.50.5-0.6-0.6-0.4
Short access day 1 total infusions0.81.63.71.31.41.4-1.51.41.31.41.21.2-1.2-1.4-1.2-1.3-1.3-1.30.3-1.9-1.0-0.7
Short access day 10 total infusions0.20.34.50.30.40.2-0.50.40.20.4-0.00.1-0.2-0.3-0.1-0.2-0.1-0.1-0.9-2.10.40.4
Short access total infusions0.20.32.50.50.60.4-0.50.50.40.50.30.3-0.3-0.4-0.3-0.3-0.2-0.3-0.6-1.6-0.10.1
Short access day 1 locomotion0.71.12.41.41.41.0-1.21.31.01.31.01.1-1.2-1.0-1.0-1.0-0.9-0.90.4-1.5-0.4-0.2
Short access day 10 total locomotion0.20.92.61.01.10.9-1.11.20.91.10.81.0-1.0-1.0-0.9-0.9-0.8-0.80.5-1.6-0.20.1
Short access total locomotion0.71.12.91.21.31.1-1.21.31.11.20.91.1-1.1-1.1-0.9-1.0-1.0-1.00.6-1.7-0.3-0.0
One hour access (0.3 mA shock)5.66.79.33.13.02.5-2.73.02.62.92.62.8-3.0-2.5-2.8-2.8-2.4-2.32.4-2.0-1.8-1.0
Compulsive drug intake1.11.62.4-1.2-1.3-1.31.5-1.4-1.3-1.4-0.8-1.41.31.31.41.31.21.3-1.41.6-0.10.0
One hour access (shock baseline)2.97.510.03.13.22.8-3.03.12.83.02.53.1-3.0-2.8-3.0-2.9-2.6-2.72.8-2.3-1.2-0.8
Social response proportion0.70.91.5-1.0-1.0-0.90.8-0.9-0.9-0.9-1.2-1.10.81.00.80.90.80.8-0.81.00.91.0
Social responses0.30.31.0-0.3-0.5-0.60.6-0.6-0.6-0.5-0.6-0.50.50.60.60.60.60.6-0.51.00.50.6
Social time0.20.40.8-0.4-0.6-0.70.7-0.6-0.7-0.6-0.5-0.60.60.70.70.70.70.7-0.50.90.40.2
Soleus weight4.814.017.43.73.94.1-3.93.94.13.94.24.0-3.9-3.9-3.8-3.9-4.0-4.03.5-2.7-2.9-2.2
Bone: stiffness2.34.26.3-2.5-2.4-2.11.9-2.1-2.0-2.1-2.5-2.32.12.12.12.11.91.9-2.10.71.71.2
Tibialis anterior weight10.235.044.2-6.0-6.1-6.56.6-6.4-6.5-6.4-5.7-5.76.46.36.46.46.36.4-4.04.94.92.9
Time to tail flick, vehicle, before self-admin0.10.20.7-0.6-0.5-0.40.3-0.4-0.3-0.4-0.4-0.50.40.40.30.40.40.4-0.8-0.30.20.4
Time to tail flick, vehicle, after self-admin0.30.62.5-1.1-0.8-0.80.7-0.5-0.8-0.6-0.6-1.00.60.90.50.60.80.8-1.6-1.0-0.40.2
Time to tail flick, test, before self-admin1.71.94.31.31.51.4-1.41.71.31.51.51.1-1.7-1.3-1.4-1.2-1.2-1.20.1-2.1-1.5-0.5
Time to tail flick, test, after self-admin0.10.10.2-0.1-0.2-0.30.2-0.2-0.2-0.2-0.3-0.10.20.20.00.10.20.20.50.50.20.2
Delta time to tail flick, vehicle, before/after SA0.40.40.9-0.7-0.6-0.70.6-0.5-0.8-0.5-0.6-0.80.50.80.50.50.70.7-0.9-0.2-0.10.2
Delta time to tail flick, test, before/after SA1.61.96.6-1.1-1.3-1.51.5-1.5-1.4-1.4-1.3-0.91.51.31.21.11.41.40.62.61.40.7
Tibia length1.23.27.1-1.8-1.8-1.71.8-1.9-1.7-1.9-2.0-1.41.91.91.91.91.61.6-0.02.12.71.5
Ambulatory time before self-admin0.20.61.3-1.0-0.9-0.80.6-0.8-0.7-0.7-1.2-0.80.80.70.70.60.70.7-0.50.21.00.8
Ambulatory time after self-admin0.10.10.60.10.20.3-0.50.20.40.3-0.00.3-0.4-0.6-0.5-0.5-0.3-0.30.8-0.30.1-0.1
Bone: tissue strength0.00.00.0-0.1-0.1-0.10.0-0.0-0.0-0.1-0.2-0.20.00.20.10.10.00.0-0.1-0.20.10.0
Total heroin consumption5.36.37.9-2.8-2.7-2.72.6-2.6-2.6-2.7-2.7-2.72.72.52.82.72.62.6-2.02.01.91.3
Bone: trabecular number0.91.73.1-1.4-1.4-1.41.1-1.3-1.3-1.2-1.8-1.61.21.21.31.21.31.3-1.7-0.01.21.1
Bone: trabecular spacing0.50.71.50.90.90.9-0.80.90.90.91.20.9-0.8-0.8-0.8-0.8-0.9-0.80.6-0.5-1.0-0.7
Bone: trabecular thickness0.20.21.00.40.50.6-0.60.50.40.50.10.3-0.5-0.5-0.5-0.5-0.5-0.6-0.2-1.0-0.20.0
Bone: trabecular tissue density3.76.69.62.72.72.7-2.62.72.62.72.82.9-2.7-2.6-2.6-2.6-2.7-2.63.1-1.3-1.7-1.6
Water consumed over 24 hours0.71.31.9-1.0-1.1-1.21.2-1.3-1.1-1.2-1.2-1.21.21.21.31.21.11.1-1.41.00.70.6
Number of responses in last shaping day0.00.00.30.20.10.10.00.1-0.00.00.20.1-0.0-0.2-0.1-0.10.1-0.0-0.20.2-0.5-0.5