Hub : Genes

LOC134483858

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression LOC134483858 0.7 0.08 0.0e+00 0.47 0.57 0.59 0.6 3.5e-59 2.0e-77 4.1e-82 9.7e-84
2 Liver gene expression LOC134483858 0.74 0.08 0.0e+00 0.4 0.44 0.43 0.43 1.3e-47 2.6e-53 2.1e-51 5.4e-52
3 IL gene expression LOC134483858 0.65 0.15 3.0e-05 0.12 0.23 0.11 0.19 9.0e-04 3.9e-06 1.4e-03 2.4e-05
4 BLA gene expression LOC134483858 0.41 0.11 1.1e-11 0.15 0.18 0.16 0.16 3.8e-08 4.5e-10 1.0e-08 6.6e-09
5 OFC gene expression LOC134483858 0.43 0.15 1.4e-03 -0 0.13 0.04 0.05 4.1e-01 6.6e-04 3.5e-02 2.1e-02
6 NAcc intron excision ratio chr20_4849094_4849321 0.12 0.05 1.3e-11 0.07 0.07 0.06 0.07 2.1e-11 1.3e-10 9.8e-10 2.9e-10
7 NAcc intron excision ratio chr20_4872524_4872736 0.04 0.02 2.0e-03 0.01 0.02 0.01 0.01 1.9e-02 1.2e-03 4.3e-03 1.8e-03
8 pVTA intron excision ratio chr20_4849320_4872736 0.3 0.12 9.9e-12 0.12 0.14 0.14 0.13 3.7e-10 2.4e-11 1.0e-11 2.5e-10
9 Liver mRNA stability LOC134483858 0.04 0.03 1.4e-03 0.01 0.02 0.03 0.02 2.2e-02 2.8e-03 6.1e-04 5.7e-03
10 IC intron excision ratio chr20_4849320_4872736 0.14 0.08 4.3e-03 0 0.02 -0 0 2.8e-01 6.3e-02 3.6e-01 2.4e-01
11 NAcc gene expression LOC134483858 0.46 0.11 0.0e+00 0.16 0.29 0.28 0.29 8.7e-23 9.4e-44 3.4e-43 4.4e-45
12 PL intron excision ratio chr20_4849320_4872736 0.05 0.03 2.4e-03 0.02 0.02 0.02 0.02 6.5e-03 2.8e-03 5.6e-03 3.1e-03
13 IC gene expression LOC134483858 0.41 0.13 3.3e-10 0.22 0.21 0.18 0.21 1.6e-09 4.6e-09 4.2e-08 2.5e-09
14 NAcc intron excision ratio chr20_4849320_4872736 0.16 0.06 1.0e-14 0.07 0.09 0.1 0.09 1.8e-11 5.8e-14 1.8e-14 5.9e-14
15 PL intron excision ratio chr20_4872524_4872736 0.07 0.04 9.1e-05 0.02 0.03 0.03 0.02 2.4e-03 5.2e-04 9.1e-04 1.3e-03
16 PL gene expression LOC134483858 0.51 0.11 0.0e+00 0.2 0.32 0.32 0.31 5.8e-22 1.5e-35 2.6e-35 1.2e-34
17 Adipose mRNA stability LOC134483858 0.07 0.04 6.4e-04 0 0.02 0.01 0.01 1.2e-01 4.6e-03 2.7e-02 2.3e-02
18 LHb gene expression LOC134483858 0.43 0.14 8.7e-05 0.1 0.08 0.01 0.04 2.7e-03 6.4e-03 1.6e-01 4.2e-02
19 Brain gene expression LOC134483858 0.36 0.11 0.0e+00 0.16 0.2 0.2 0.18 2.3e-14 2.1e-18 8.4e-19 6.5e-17
20 RMTg gene expression LOC134483858 0.29 0.14 2.3e-03 0.03 0.16 0.13 0.12 6.0e-02 6.1e-05 2.4e-04 3.5e-04
21 Liver intron excision ratio chr20_4872524_4872736 0.07 0.04 7.3e-03 -0 -0 -0 -0 8.6e-01 5.6e-01 4.4e-01 5.9e-01
22 pVTA gene expression LOC134483858 0.43 0.14 0.0e+00 0.17 0.22 0.23 0.23 1.3e-13 5.7e-18 2.5e-18 3.8e-18
23 Liver intron excision ratio chr20_4849094_4849321 0.54 0.13 6.9e-11 0.02 0.01 0.04 0.01 5.5e-03 1.3e-02 4.6e-05 3.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density1.62.76.8-0.4-0.21.80.92.02.32.1-2.6-1.5-2.51.1-2.41.3-2.52.41.01.3-1.71.30.30.90.40.8
Area under the delay curve0.40.42.10.30.6-0.60.2-0.4-1.0-0.51.00.60.80.21.1-0.40.8-1.00.20.30.10.10.40.2-0.0-1.5
BMI with tail0.61.96.62.01.71.31.10.7-1.21.20.72.60.91.10.91.70.5-1.01.4-1.12.11.22.10.41.6-0.3
BMI without tail0.72.26.32.42.1-0.10.8-0.5-2.30.02.22.52.00.72.11.01.5-2.00.4-0.91.70.41.20.51.2-0.9
Body weight1.56.516.52.11.8-1.0-0.2-1.7-3.9-1.63.84.13.9-0.34.0-0.43.5-4.10.1-2.63.7-0.31.8-0.60.8-2.1
Weight adjusted by age2.03.18.50.60.7-0.60.0-1.0-2.7-1.82.72.22.3-0.02.8-1.12.8-2.80.3-0.72.9-0.41.20.30.5-2.0
Bone surface0.40.73.1-0.9-1.0-0.7-1.1-0.80.5-0.5-0.6-0.70.1-0.9-0.3-1.60.10.2-1.0-0.9-0.3-1.2-0.9-0.8-1.80.1
Bone volume0.20.31.2-0.3-0.20.4-0.10.41.00.7-1.1-0.6-0.70.1-0.9-0.5-0.80.80.00.1-0.60.0-0.10.2-0.60.5
Breakpoint value in progressive ratio session0.40.51.7-0.7-0.9-0.5-0.8-0.50.6-0.2-0.8-0.8-0.3-0.5-0.7-0.5-0.50.6-0.8-0.4-0.5-0.3-1.1-0.8-1.11.3
Number of licking bursts1.32.14.9-1.8-2.0-2.0-2.2-1.70.4-1.4-0.2-1.00.5-2.2-0.2-1.20.30.1-2.0-1.3-0.2-2.0-1.9-2.0-1.30.1
Context. condit. distance diff. score3.13.712.8-3.6-3.3-1.1-2.1-0.42.8-0.6-2.2-3.0-1.5-2.1-2.1-1.6-1.61.8-1.4-0.3-1.9-0.9-1.6-1.7-1.00.9
Locomotion velocity, session 10.70.83.3-1.1-1.0-0.5-0.4-0.10.9-0.6-0.2-1.8-0.7-0.2-0.6-1.4-0.40.7-0.40.9-1.7-0.7-1.00.2-1.40.1
Locomotion distance, session 11.11.43.8-0.5-0.41.00.41.21.81.3-1.8-1.3-1.80.4-1.90.6-1.91.80.40.8-1.70.5-0.20.20.30.4
Locomotion velocity, session 20.60.71.7-1.0-1.1-0.8-1.0-0.60.9-0.2-0.8-1.0-0.3-1.0-0.8-0.4-0.50.7-1.0-0.4-1.2-0.9-1.2-0.7-1.30.2
Locomotion distance, session 20.50.61.8-0.9-0.70.90.11.01.40.8-1.2-0.8-1.30.2-1.30.3-1.01.20.60.5-0.50.40.30.30.40.3
Locomotion velocity, session 30.20.20.90.70.60.10.30.20.20.8-0.40.3-0.30.3-0.40.9-0.60.5-0.00.30.00.2-0.30.10.50.7
Locomotion distance, session 31.31.43.8-0.7-0.60.70.21.01.81.2-1.9-1.4-1.80.2-1.90.7-1.91.90.21.0-1.10.7-0.50.10.61.4
Stereotopy head waving bouts, day 32.12.44.5-0.2-0.5-1.7-1.3-2.0-1.8-2.12.00.92.1-1.31.8-1.52.1-1.9-1.4-1.51.7-1.8-0.7-1.2-1.1-1.2
Stereotopy head waving duration, day 31.41.74.10.20.1-1.5-0.7-1.5-1.7-1.72.00.91.8-0.61.9-1.12.0-1.8-0.8-0.81.4-1.3-0.3-0.3-0.7-1.6
Locomotion velocity, session 72.73.07.3-1.4-0.91.90.92.32.61.7-2.3-1.6-2.70.8-2.50.8-2.22.31.61.6-0.91.50.91.11.31.0
Locomotion distance, session 73.13.99.9-1.6-0.91.81.02.32.91.8-2.5-2.3-3.20.8-2.80.9-2.62.81.42.4-1.81.60.31.21.11.9
Stereotopy head waving bouts, day 70.30.31.50.60.4-1.2-0.2-0.9-0.4-0.30.5-0.20.4-0.50.40.40.3-0.1-0.80.3-0.3-0.6-1.1-0.1-0.50.2
Stereotopy head waving duration, day 70.40.41.00.80.6-1.0-0.2-0.9-0.9-0.60.90.40.9-0.40.90.20.8-0.7-0.7-0.20.5-0.7-0.7-0.2-0.3-0.6
Locomotion velocity, session 83.13.77.7-2.7-2.8-2.6-2.7-2.20.8-2.40.1-1.70.7-2.60.1-2.70.4-0.3-2.3-1.3-0.7-2.4-2.1-2.3-2.3-0.4
Locomotion distance, session 82.43.411.8-3.4-3.2-0.2-1.70.23.0-0.1-2.6-2.8-1.9-1.7-2.5-1.1-1.92.1-0.8-0.3-1.5-0.6-1.1-1.5-0.50.9
Degree of sensitization distance0.50.51.4-1.0-1.0-0.6-0.8-0.7-0.1-1.20.4-0.50.5-1.00.4-1.20.6-0.5-0.6-0.5-0.2-1.0-0.4-0.7-1.00.0
Degree of sensitization stereotypy0.40.41.80.20.1-0.8-0.1-0.30.70.4-0.7-1.0-0.5-0.3-0.70.5-0.80.9-0.70.7-1.3-0.2-1.30.0-0.40.6
Conditioned locomotion0.91.13.3-0.5-0.7-0.9-1.3-1.2-0.6-0.90.30.81.2-1.10.7-1.61.1-1.0-0.9-1.80.8-1.3-0.2-1.3-1.3-0.3
Cocaine response after cond. corrected0.20.31.0-0.9-0.90.4-0.60.20.40.0-0.60.2-0.2-0.6-0.50.3-0.00.20.0-1.00.8-0.30.4-0.90.30.4
Cocaine response after cond. not corrected1.11.33.3-0.7-1.0-1.2-1.5-1.4-0.7-1.40.70.51.3-1.50.8-0.81.1-1.0-1.2-1.81.0-1.4-0.6-1.7-0.80.1
Cocaine response before conditioning3.23.87.90.80.3-2.6-1.3-2.8-2.4-2.42.71.02.8-1.52.6-2.02.4-2.4-2.0-1.50.9-1.8-1.5-1.2-1.8-0.6
Saline control response2.33.010.93.33.21.02.20.7-2.20.91.92.41.12.01.81.11.0-1.51.50.81.11.31.81.61.3-0.7
Bone: connectivity density0.81.23.9-0.8-0.71.40.31.31.71.2-2.0-1.1-1.70.5-1.80.6-1.51.60.60.4-1.00.80.30.4-0.1-0.2
Bone: cortical apparent density0.71.03.71.91.81.11.20.7-1.01.10.21.30.31.20.51.00.1-0.51.0-0.11.10.81.20.50.4-0.3
Bone: cortical area0.10.20.7-0.1-0.1-0.9-0.6-0.7-0.1-0.40.20.20.6-0.60.4-0.60.3-0.4-0.6-0.70.0-0.3-0.4-0.1-0.3-0.7
Bone: cortical porosity0.40.42.10.40.4-1.10.2-0.5-0.1-0.40.5-1.1-0.00.10.30.5-0.10.1-0.51.4-1.30.1-1.10.7-0.1-0.2
Bone: cortical porosity0.50.52.1-0.1-0.1-1.5-0.2-0.9-0.3-1.00.8-1.20.3-0.20.6-0.30.4-0.2-0.71.1-1.0-0.5-1.20.6-0.5-0.8
Bone: cortical thickness0.61.03.41.71.60.91.20.90.31.7-0.70.6-0.41.0-0.41.8-1.10.50.80.4-0.31.40.70.80.9-0.5
Bone: cortical thickness0.91.14.52.12.01.31.40.9-0.41.7-0.31.30.00.90.11.4-0.5-0.01.0-0.10.71.11.10.40.5-0.7
Bone: cortical tissue density0.60.93.31.81.71.01.10.6-1.10.90.31.30.41.20.60.80.2-0.60.9-0.21.10.71.20.40.3-0.4
Condit. Reinf. active minus inactive responses0.30.31.90.10.30.40.70.50.20.10.1-0.9-0.70.6-0.3-0.2-0.30.50.41.4-1.1-0.0-0.21.0-0.3-0.1
Condit. Reinf. active-inactive response ratio0.40.41.51.21.10.50.90.3-0.90.10.60.30.20.70.60.80.2-0.40.40.6-0.10.20.30.70.2-0.9
Condit. Reinf. active responses0.50.61.90.10.31.11.01.10.40.6-0.3-0.7-1.00.9-0.60.0-0.70.70.91.4-0.80.70.31.20.40.6
Condit. Reinf. inactive responses1.72.14.3-0.10.21.91.22.01.61.7-1.7-0.9-2.11.3-1.80.8-1.91.81.31.5-1.01.70.71.21.01.6
Incentive salience index mean0.70.83.0-1.6-1.3-0.3-0.60.11.3-0.3-0.8-1.7-0.9-0.4-1.0-1.0-0.71.0-0.30.6-1.5-0.3-0.70.1-0.70.4
Condit. Reinf. lever presses1.72.39.5-3.1-2.8-0.6-1.7-0.22.4-0.5-1.8-2.3-1.3-1.3-1.8-1.3-1.11.5-0.9-0.4-1.4-0.5-1.0-1.0-0.91.0
Condit. Reinf. active minus inactive responses0.40.51.80.40.4-0.9-0.3-0.9-0.9-1.01.30.41.2-0.21.3-0.41.0-1.2-0.4-0.20.1-0.1-0.20.2-0.1-0.7
Condit. Reinf. active-inactive response ratio1.11.33.9-0.0-0.1-1.4-0.7-1.4-1.3-1.82.00.41.6-0.61.7-0.81.7-1.6-0.8-0.50.3-0.7-0.40.0-0.3-1.2
Condit. Reinf. active responses0.10.10.20.40.3-0.30.1-0.3-0.4-0.30.40.10.40.20.5-0.10.3-0.3-0.10.2-0.10.1-0.20.40.1-0.1
Condit. Reinf. inactive responses0.20.30.90.80.70.70.60.60.11.0-0.60.3-0.40.6-0.40.5-0.50.50.40.2-0.10.50.20.30.30.2
Condit. Reinf. lever presses0.50.72.1-0.20.10.10.50.60.90.5-0.7-1.2-1.00.6-0.70.9-1.00.90.31.4-1.40.9-0.31.20.60.5
Condit. Reinf. lever reinforcers received0.10.10.30.30.2-0.4-0.0-0.4-0.2-0.40.4-0.20.30.00.3-0.10.2-0.2-0.30.3-0.4-0.0-0.50.4-0.10.0
Conditioned reinforcement - actives0.20.41.10.40.60.90.90.9-0.00.6-0.2-0.1-0.51.0-0.10.4-0.20.21.00.8-0.30.70.80.90.6-0.1
Conditioned reinforcement - inactives0.30.51.50.50.70.81.10.8-0.50.20.40.4-0.21.20.30.20.4-0.21.11.00.20.50.80.90.9-0.2
Conditioned locomotion0.20.30.8-0.20.20.50.60.6-0.2-0.10.3-0.2-0.20.70.3-0.20.4-0.30.90.9-0.10.40.90.90.50.2
Patch foraging indifference point 0 sec1.32.38.12.82.50.91.70.4-2.50.32.22.01.21.51.80.81.5-1.51.20.31.50.61.41.30.8-0.3
Patch foraging indifference point AUC0.40.61.50.1-0.1-1.1-0.7-1.2-0.9-0.90.9-0.30.9-0.70.6-0.50.7-0.5-1.2-0.60.1-1.1-1.1-0.6-1.2-0.0
Delay disc. indifference point, 0s delay0.30.43.1-0.7-0.6-0.6-0.5-0.4-0.1-0.80.60.10.5-0.40.5-0.80.7-0.6-0.1-0.20.2-0.60.1-0.0-0.1-1.8
Delay disc. indifference point, 16s delay0.40.51.40.91.20.51.00.7-0.20.70.00.5-0.21.10.30.8-0.2-0.10.81.0-0.01.00.90.60.4-0.6
Delay disc. indifference point, 2s delay1.21.33.3-0.2-0.1-1.3-0.5-1.2-1.7-1.81.70.31.5-0.51.7-1.51.8-1.6-0.4-0.10.3-0.9-0.2-0.3-0.7-1.7
Delay disc. indifference point, 24s delay0.91.02.71.21.4-0.11.0-0.0-1.6-0.51.50.70.90.81.6-0.21.3-1.30.61.00.80.20.70.70.4-1.6
Delay disc. indifference point, 4s delay1.11.13.00.60.5-1.1-0.4-1.2-1.7-1.11.60.91.6-0.41.6-0.61.4-1.5-0.6-0.60.4-0.8-0.2-0.6-0.8-1.1
Delay disc. indifference point, 8s delay0.30.31.70.20.6-0.10.50.1-0.5-0.20.60.30.30.50.7-0.20.4-0.60.50.7-0.20.60.70.70.5-1.3
Indifference point function ln k0.40.82.1-1.1-1.2-1.1-1.2-0.80.7-0.6-0.5-0.7-0.0-1.1-0.4-1.20.10.3-1.1-0.4-0.9-1.0-1.2-0.7-1.50.4
Indifference point function log k0.40.82.1-1.1-1.2-1.1-1.2-0.80.7-0.6-0.5-0.7-0.0-1.1-0.4-1.20.10.3-1.1-0.4-0.9-1.0-1.2-0.7-1.50.4
Patch foraging total patch changes 0 sec1.32.58.62.92.61.01.90.5-2.50.42.12.01.11.71.71.01.5-1.51.30.41.40.81.41.40.9-0.0
Patch foraging total patch changes 12 sec0.81.14.12.01.70.41.0-0.1-2.00.01.51.21.00.91.30.50.9-1.10.3-0.11.40.00.50.5-0.2-0.9
Patch foraging total patch changes 18 sec1.62.57.22.72.42.12.11.5-1.11.80.51.5-0.12.00.32.30.0-0.21.70.41.81.41.81.51.6-0.2
Patch foraging total patch changes 24 sec1.62.75.41.92.02.32.32.1-0.12.1-0.40.5-1.22.3-0.62.3-1.00.82.01.60.22.01.62.21.70.7
Patch foraging total patch changes 6 sec1.52.37.02.62.51.22.00.9-2.00.81.91.60.71.91.31.40.9-1.11.50.80.81.21.61.61.3-0.6
Patch foraging time to switch 0 sec0.61.33.70.70.71.71.01.40.21.3-0.81.3-0.41.0-0.31.5-0.50.11.4-0.31.51.61.90.61.9-1.2
Patch foraging water rate 0 sec0.30.62.40.60.5-0.10.3-0.3-1.3-0.71.61.01.00.21.2-0.31.3-1.10.2-0.11.0-0.10.50.10.20.5
Patch foraging water rate 12 sec0.30.61.70.60.60.80.80.90.51.3-0.8-0.2-0.90.7-0.91.1-0.90.90.60.6-0.40.60.20.30.41.3
Patch foraging water rate 18 sec0.20.31.00.90.80.30.50.2-0.70.20.31.00.40.60.60.50.4-0.60.50.00.50.60.70.20.70.0
Patch foraging water rate 24 sec0.10.20.80.70.60.50.50.30.00.6-0.20.4-0.10.5-0.20.3-0.30.20.2-0.00.20.30.10.10.40.9
Patch foraging water rate 6 sec0.10.20.60.60.50.40.30.2-0.30.5-0.00.8-0.00.3-0.10.6-0.10.10.3-0.20.50.10.2-0.20.40.8
Seeking ratio, delayed vs. immediate footshock1.01.23.31.20.5-1.3-0.9-1.8-1.2-0.60.80.31.4-1.30.80.10.3-0.6-1.8-1.5-0.1-0.8-1.7-1.5-1.40.4
Distance traveled before self-admin0.40.52.7-0.7-0.9-0.4-1.1-0.70.0-0.4-0.30.00.5-1.0-0.0-0.50.0-0.2-0.7-1.61.6-0.5-0.3-1.0-0.2-0.5
Distance traveled after self-admin1.31.64.20.3-0.1-1.4-1.3-1.8-1.3-1.21.00.81.8-1.31.2-0.71.1-1.3-1.6-2.01.1-1.4-0.9-1.4-1.3-0.2
Extensor digitorum longus weight0.10.51.8-1.3-1.1-1.0-1.1-0.80.1-0.90.1-0.20.5-0.80.3-1.20.4-0.4-0.6-0.7-0.1-0.5-0.2-0.8-0.4-0.4
Bone: elastic displacement0.91.03.51.11.30.91.51.1-0.10.80.1-0.2-0.61.40.01.9-0.60.21.21.7-0.81.30.71.21.2-0.6
Bone: elastic work0.20.20.60.70.80.10.70.3-0.40.20.40.10.20.60.50.70.1-0.40.60.50.00.60.60.60.2-0.8
Bone: endosteal estimation3.67.916.0-1.3-1.6-3.4-2.9-3.6-2.6-4.03.21.23.6-2.73.2-3.73.9-3.3-2.5-2.92.2-3.2-1.1-1.7-2.1-1.0
Bone: endosteal perimeter2.24.711.0-2.3-2.5-2.9-3.0-2.8-0.7-3.11.4-0.02.0-2.81.3-3.32.2-1.6-2.4-2.41.0-2.7-1.5-1.6-1.6-0.3
Epididymis fat weight3.913.528.85.05.05.14.84.2-0.95.0-0.83.9-1.14.4-0.45.4-1.40.44.51.02.14.64.63.14.60.6
Delta time in closed arm before/after self-admin0.50.54.1-0.1-0.1-0.1-0.1-0.2-0.7-0.51.00.70.7-0.10.7-0.50.9-0.80.3-0.50.7-0.40.50.40.2-2.0
Delta time in open arm before/after self-admin0.20.20.50.50.60.50.70.50.10.50.1-0.1-0.40.7-0.20.5-0.20.30.40.7-0.10.40.30.70.20.6
Diff in mean of infusions in LGA sessions1.11.46.4-1.4-1.30.5-0.50.61.90.6-2.1-1.1-1.4-0.2-1.80.1-1.41.6-0.10.1-0.80.5-0.3-0.00.12.5
Delay discount exponential model param0.40.52.2-0.4-0.60.7-0.20.51.10.6-1.0-0.5-0.9-0.2-1.20.4-0.91.1-0.1-0.30.00.1-0.3-0.10.11.5
Extinction: sum of active levers before priming0.50.51.7-1.3-1.2-0.7-1.0-0.70.2-1.0-0.1-0.50.2-0.8-0.1-1.10.4-0.1-0.7-0.60.4-0.9-0.7-0.7-0.90.6
Active lever presses in extinction session 61.21.23.10.40.81.41.51.50.10.9-0.2-0.1-0.91.6-0.30.6-0.30.41.71.6-0.21.81.41.61.20.1
Bone: final force1.01.55.61.71.60.60.80.0-1.60.11.32.41.40.31.60.61.2-1.60.7-1.02.10.61.50.10.8-1.1
Bone: final moment0.81.44.31.51.50.60.90.2-1.50.21.22.11.20.51.40.71.1-1.40.9-0.62.00.71.50.51.0-1.0
Food consumed during 24 hour testing period0.70.93.1-0.4-0.6-0.7-1.0-0.9-0.9-1.00.91.21.3-0.91.0-0.71.4-1.2-0.5-1.61.8-0.60.3-1.00.0-0.2
Glucose2.53.913.9-3.2-2.9-2.5-2.5-2.2-0.3-3.51.5-1.11.2-2.31.0-3.71.9-1.2-1.8-0.70.6-2.2-1.5-1.1-0.6-0.1
Heart weight1.52.49.30.90.9-1.20.1-1.2-2.5-1.73.11.42.10.12.6-1.12.1-2.4-0.1-0.10.6-0.20.40.50.1-2.5
Delay discount hyperbolic model param0.50.52.0-0.4-0.60.8-0.00.61.20.8-1.1-0.5-1.0-0.1-1.30.5-1.01.10.1-0.30.10.2-0.1-0.00.31.4
Intermittent access intake day 1-15 change0.10.21.20.30.1-0.5-0.3-0.6-0.2-0.20.1-0.20.3-0.40.1-0.20.1-0.1-0.7-0.4-0.3-0.9-0.7-0.4-0.4-1.1
Intermittent access intake escalation0.10.21.41.21.00.10.50.0-0.30.50.10.10.10.40.10.6-0.20.0-0.00.2-0.4-0.1-0.20.20.1-1.0
Intermittent access intake escalation 20.20.32.3-0.1-0.2-0.7-0.4-0.5-0.1-0.3-0.0-0.40.2-0.40.1-0.40.20.0-0.5-0.0-0.5-0.7-0.6-0.4-0.6-1.5
Intermitt. access day 1 inactive lever presses0.62.35.2-1.6-2.1-1.7-2.3-1.90.0-1.8-0.00.01.0-2.00.1-1.60.9-0.4-1.9-2.10.1-2.2-1.7-2.2-1.50.7
Intermitt. access day 15 inactive lever presses0.20.41.10.30.1-0.3-0.1-0.5-0.9-0.71.10.70.8-0.10.8-0.40.9-0.8-0.2-0.51.0-0.40.10.10.2-0.6
Intermitt. access escalation Index1.72.510.1-1.9-2.1-0.7-1.7-0.62.00.0-2.0-1.6-0.9-1.4-1.9-0.3-1.61.6-1.5-1.2-1.3-0.4-1.7-1.6-1.23.2
Intermittent access day 1 total infusions1.22.07.4-0.40.31.71.72.10.80.9-0.6-1.5-1.81.9-0.80.5-0.61.02.12.7-0.91.21.31.91.30.5
Intermittent access day 15 total infusions0.71.13.60.71.11.21.61.40.11.0-0.3-0.7-1.01.6-0.40.9-0.50.61.41.9-0.90.80.81.41.00.1
Intermittent access terminal intake (last 3 days)0.70.93.70.81.11.01.61.2-0.40.60.2-0.6-0.71.70.10.60.00.11.41.9-0.60.70.91.51.0-0.3
Intermittent access total infusions1.11.34.90.51.01.31.71.60.00.8-0.1-0.7-1.11.8-0.20.7-0.30.41.72.2-0.80.91.11.71.20.3
Intermittent access day 1 locomotion0.81.12.50.30.71.41.41.50.30.9-0.1-0.3-0.91.4-0.30.8-0.40.41.61.40.11.31.31.61.50.2
Intermittent access day 15 total locomotion0.40.72.81.01.10.30.70.1-1.2-0.11.10.80.80.51.20.10.8-1.10.70.01.20.31.10.40.6-1.7
Intermittent access total locomotion0.80.91.91.01.31.01.41.0-0.50.60.50.3-0.21.30.50.70.1-0.41.31.10.50.91.31.31.1-1.4
Intermittent access standard deviation0.81.64.81.91.80.51.10.1-1.80.11.62.21.11.01.50.41.4-1.40.8-0.11.30.01.11.11.1-2.0
Left kidney weight0.83.911.12.62.3-0.70.3-1.2-3.1-0.42.73.33.00.33.00.42.1-3.00.1-2.02.50.41.4-0.10.8-2.0
Right kidney weight0.94.012.42.31.9-0.50.1-1.2-3.1-0.62.53.53.00.13.00.32.2-3.00.2-2.33.00.31.5-0.70.8-1.5
Cocaine induced anxiety0.81.13.6-1.1-1.3-0.8-1.5-1.00.5-0.6-0.6-0.20.3-1.4-0.4-0.9-0.20.2-1.4-1.6-0.2-1.0-1.1-1.9-1.31.5
Post-drug Anxiety0.50.52.0-0.4-0.7-0.8-1.1-1.0-0.1-0.60.20.30.7-1.00.2-0.40.1-0.3-1.2-1.4-0.0-0.5-0.7-1.1-0.70.7
Baseline Anxiety0.40.53.20.60.70.10.50.1-0.7-0.21.10.40.50.50.80.10.7-0.70.40.30.50.20.61.20.5-1.8
Tail length2.18.319.60.2-0.2-3.8-2.1-3.9-3.6-4.04.41.54.2-2.24.0-2.53.9-3.9-2.5-2.21.7-2.7-1.4-1.6-1.5-1.8
Length with tail2.410.525.20.40.1-3.4-2.0-3.8-4.2-4.25.02.74.9-2.14.9-3.14.8-4.8-1.9-2.83.1-2.5-0.3-1.4-1.1-2.4
Length without tail1.96.316.00.40.2-1.4-1.2-2.0-3.3-2.53.33.33.7-1.23.7-1.93.9-3.9-0.3-3.04.0-1.11.5-1.3-0.2-2.0
Times rat made contact with spout1.61.83.71.41.61.41.81.60.91.9-0.9-0.4-1.41.7-1.01.6-1.61.21.31.9-1.21.30.51.61.00.0
Lifetime Intake0.91.14.30.61.01.31.71.5-0.20.60.1-0.5-0.81.80.00.6-0.10.21.72.1-0.40.91.21.61.30.2
Liver weight, left2.43.97.5-1.2-1.5-2.3-2.4-2.6-1.6-2.71.81.02.4-2.41.8-1.82.0-2.0-2.0-2.61.8-2.0-1.0-2.7-1.1-0.5
Liver weight, right2.64.59.6-1.6-1.7-2.5-2.4-2.7-1.5-3.12.10.22.4-2.22.0-2.92.6-2.2-1.9-2.11.2-2.6-1.0-2.3-2.1-1.4
Locomotor activity1.52.35.90.2-0.4-2.3-1.6-2.4-1.2-1.61.10.51.8-1.91.2-0.81.0-1.1-2.3-1.80.6-1.9-2.0-2.1-1.20.3
Locomotor testing distance0.91.63.6-0.2-0.6-1.7-1.5-1.9-0.7-1.30.80.41.4-1.70.8-0.60.9-0.8-1.8-1.81.2-1.6-1.5-1.8-0.91.0
Locomotor testing rearing0.71.54.2-0.1-0.4-1.1-1.1-1.5-1.1-1.41.31.11.6-1.21.2-0.91.4-1.3-1.2-1.82.0-1.3-0.6-1.3-0.40.5
Locomotion in novel chamber0.00.10.30.10.3-0.0-0.00.10.30.5-0.40.4-0.0-0.1-0.1-0.3-0.20.10.0-0.1-0.50.20.2-0.2-0.2-0.4
Locomotion in novel chamber post-restriction0.40.72.11.01.20.30.60.1-1.10.01.11.40.90.61.20.30.7-1.20.6-0.41.00.61.10.20.6-0.9
Fecal boli incidents, locomotor time 10.40.61.5-0.4-0.11.10.71.20.70.7-0.7-0.2-1.00.9-0.70.2-0.20.61.20.90.30.91.01.20.80.4
Change in fecal boli incidents, locomotor task2.72.65.0-0.3-0.7-1.8-1.6-2.2-1.5-2.21.60.72.1-1.71.7-1.61.8-1.8-1.7-1.90.7-2.0-1.0-2.0-1.9-0.1
Time >=10cm from walls, locomotor time 12.82.98.7-0.6-0.9-1.5-1.8-2.1-1.6-1.81.31.52.3-1.71.6-1.72.0-1.9-1.5-3.02.3-1.6-0.3-2.1-1.4-0.4
Bouts of movement, locomotor time 10.60.72.5-0.5-0.7-0.4-0.7-0.31.00.3-1.0-0.9-0.6-0.6-1.10.3-1.11.0-0.9-0.3-1.6-0.2-1.2-0.4-0.41.1
Total resting periods, locomotor time 10.40.51.5-0.6-0.7-0.5-0.7-0.40.90.1-0.8-0.9-0.4-0.6-0.80.2-0.70.8-0.8-0.3-1.2-0.3-1.0-0.3-0.41.0
Rest time, locomotor task time 10.20.30.8-0.9-0.8-0.8-0.8-0.50.4-0.3-0.5-0.7-0.1-0.5-0.4-0.40.00.3-0.6-0.1-0.3-0.7-0.8-0.1-0.60.7
Distance moved, locomotor task time 10.40.61.81.00.90.30.5-0.1-1.3-0.41.31.20.90.21.20.00.9-1.20.3-0.31.00.20.8-0.30.3-0.8
Vertical activity count, locomotor time 10.61.43.71.81.60.81.00.2-1.8-0.01.51.91.10.71.50.71.0-1.50.7-0.41.60.61.3-0.00.8-1.3
Time >=10cm from walls, locomotor time 22.13.28.80.40.3-1.0-0.4-1.3-2.6-2.12.61.82.4-0.62.8-1.72.9-2.8-0.2-1.13.0-1.00.8-0.6-0.0-1.8
Bouts of movement, locomotor time 20.30.51.80.2-0.2-1.1-0.7-1.0-0.0-0.50.2-0.40.4-0.80.1-0.4-0.1-0.0-1.2-0.4-1.0-1.0-1.3-0.7-1.00.0
Total resting periods, locomotor time 20.61.13.6-0.3-0.7-1.6-1.2-1.40.2-0.90.1-1.00.5-1.20.0-0.8-0.20.1-1.7-0.5-1.4-1.4-1.9-1.0-1.60.1
Rest time, locomotor task time 21.51.95.0-2.1-2.2-1.5-2.2-1.40.9-1.0-0.8-0.90.3-1.9-0.6-1.40.00.3-1.7-1.7-0.1-1.7-1.5-1.6-1.60.8
Distance moved, locomotor task time 22.53.07.21.82.31.72.21.5-1.70.51.61.90.51.91.60.91.1-1.52.31.21.71.72.71.52.2-2.0
Vertical activity count, locomotor time 21.82.45.21.61.91.21.70.9-1.80.01.81.90.81.51.80.61.4-1.71.80.81.91.32.31.21.8-2.1
Light reinforcement 10.30.85.60.50.10.3-0.4-0.4-0.8-0.10.41.60.9-0.70.60.30.6-0.8-0.3-1.92.4-0.90.3-1.20.40.3
Light reinforcement 20.40.74.0-0.2-0.20.1-0.4-0.3-0.8-0.50.81.50.9-0.40.70.31.0-0.90.1-1.32.0-0.60.6-0.70.7-0.5
Bone: marrow area3.78.016.2-1.1-1.4-3.4-2.8-3.6-2.7-4.03.31.43.7-2.73.3-3.74.0-3.4-2.4-2.92.2-3.1-1.0-1.7-2.1-1.1
Bone: maximum diameter1.32.47.1-2.1-2.1-2.2-2.3-1.90.1-2.10.5-0.71.0-2.00.5-2.71.2-0.7-1.8-1.3-0.4-1.9-1.4-1.0-1.3-0.7
Bone: maximum force0.50.82.71.00.90.20.4-0.1-1.2-0.11.01.61.10.21.2-0.31.1-1.30.5-0.81.60.21.00.30.3-1.0
Bone: maximum moment0.40.72.10.80.80.20.4-0.0-1.0-0.21.01.30.90.41.2-0.21.1-1.20.6-0.41.50.31.00.70.5-0.8
Mean time between licks in bursts1.43.57.9-2.7-2.8-2.3-2.7-2.00.7-1.9-0.4-1.80.3-2.5-0.5-2.40.50.3-2.3-1.2-0.9-2.0-2.4-2.0-2.60.4
Mean num. licks in bursts2.23.58.22.42.62.42.82.3-0.02.2-0.20.7-1.02.9-0.22.0-1.00.52.42.1-0.42.41.92.51.7-0.1
Cd content in liver1.82.06.70.50.82.41.82.1-0.20.90.31.1-0.81.9-0.00.6-0.2-0.12.41.01.11.72.51.42.6-0.4
Co content in liver1.41.64.41.71.51.31.30.8-1.30.41.22.10.71.31.20.60.8-1.21.4-0.12.01.11.90.71.6-1.2
Cu content in liver1.61.94.01.01.11.51.51.60.91.9-1.5-0.4-1.51.5-1.32.0-2.01.51.11.4-1.51.50.41.21.40.9
Fe content in liver0.70.82.41.11.21.11.11.0-0.41.00.21.1-0.11.20.21.2-0.2-0.21.20.30.61.21.30.71.6-0.2
K content in liver0.80.83.4-1.1-0.90.0-0.50.31.70.6-1.8-1.2-1.1-0.1-1.40.0-1.51.2-0.30.1-0.70.1-0.4-0.7-0.20.3
Mg content in liver2.72.76.2-2.4-2.5-1.5-2.2-1.31.7-0.9-1.6-2.0-0.3-2.0-1.1-1.7-0.80.9-1.9-1.2-1.3-1.6-1.9-2.3-1.90.0
Mn content in liver2.52.88.7-2.7-2.6-1.8-2.4-1.70.8-1.9-0.2-1.10.7-2.30.1-3.00.7-0.4-1.7-1.60.4-2.1-1.1-2.0-1.4-0.4
Na content in liver0.40.52.00.60.3-0.1-0.0-0.00.60.8-1.0-0.2-0.5-0.0-0.71.3-1.30.8-0.40.1-0.60.3-0.7-0.60.11.4
Rb content in liver0.10.20.6-0.8-0.50.60.10.50.50.1-0.4-0.3-0.50.3-0.4-0.1-0.30.30.50.10.00.40.50.10.50.2
Se content in liver2.42.96.0-2.0-2.2-2.3-2.2-2.00.3-2.10.4-1.50.6-2.50.1-2.10.6-0.1-2.3-0.8-0.9-2.2-2.3-2.0-1.80.5
Sr content in liver0.30.31.1-0.2-0.1-0.00.10.1-0.5-0.51.00.60.40.20.7-0.40.6-0.70.60.20.80.20.9-0.10.8-0.4
Zn content in liver0.30.31.6-0.7-0.60.1-0.3-0.1-0.3-0.80.20.10.3-0.20.4-1.30.8-0.50.1-0.20.8-0.60.3-0.1-0.1-1.3
Bone: minimum diameter1.62.86.1-1.7-1.7-2.3-2.2-2.2-0.7-2.41.20.21.8-2.31.3-2.51.9-1.5-1.8-1.90.7-1.7-1.0-1.1-1.1-0.5
Time in familiar zone, hab. session 13.93.87.00.81.42.12.12.51.62.6-2.0-0.7-2.42.2-1.82.1-2.22.01.92.6-1.82.41.02.11.60.1
Time in novel zone, hab. session 13.23.25.7-0.4-0.8-1.9-1.7-2.3-1.8-2.42.10.92.3-1.71.9-1.82.1-2.0-1.6-2.21.9-2.3-0.8-1.9-1.3-0.5
Total zone transitions, hab. session 10.60.91.9-0.8-1.0-0.3-0.7-0.21.30.3-1.4-1.2-0.8-0.9-1.30.3-1.31.2-0.8-0.3-1.0-0.5-1.2-1.3-0.81.1
Total locomotion distance, hab. session 10.71.02.7-1.0-1.1-0.1-0.70.11.60.6-1.7-1.2-1.1-0.8-1.60.3-1.41.4-0.6-0.3-1.0-0.2-0.9-1.1-0.61.3
Locomotion velocity, hab. session 10.50.71.6-0.8-0.9-0.2-0.7-0.11.30.4-1.3-1.1-0.8-0.8-1.20.3-1.21.1-0.6-0.3-1.1-0.1-0.9-1.0-0.61.1
Time in familiar zone, hab. session 20.40.41.60.90.50.30.10.10.21.0-1.10.1-0.3-0.3-0.81.3-1.10.8-0.5-0.5-0.3-0.0-0.6-1.0-0.50.1
Time in novel zone, hab. session 20.80.82.90.20.50.20.80.3-0.9-0.71.70.60.51.01.2-0.61.4-1.11.00.90.80.21.11.50.9-0.9
Total zone transitions, hab. session 20.50.72.0-0.5-0.8-0.1-0.9-0.21.10.5-1.3-0.3-0.4-0.9-1.10.5-1.10.8-0.8-1.2-0.3-0.5-0.6-1.4-0.51.2
Total locomotion distance, hab. session 21.21.65.3-1.2-1.30.3-0.90.32.11.1-2.3-1.0-1.4-1.0-2.10.6-1.91.8-0.6-0.8-0.8-0.3-0.7-1.4-0.41.3
Locomotion velocity, hab. session 21.52.06.3-1.5-1.70.1-1.10.22.31.0-2.5-1.4-1.5-1.2-2.30.4-2.02.0-0.8-0.8-1.1-0.3-1.0-1.4-0.61.6
Novel to familiar place preference ratio0.10.10.7-0.10.20.20.50.3-0.1-0.00.5-0.5-0.30.40.00.00.20.10.40.8-0.0-0.00.20.40.10.1
Novelty place preference0.10.10.5-0.10.2-0.10.30.1-0.3-0.30.7-0.4-0.00.20.3-0.20.4-0.10.20.7-0.0-0.2-0.00.2-0.2-0.1
Time in novel zone, NPP test0.10.10.90.10.2-0.20.3-0.1-0.5-0.40.9-0.40.10.20.4-0.20.6-0.30.10.7-0.1-0.3-0.10.2-0.2-0.3
Total zone transitions, NPP test1.01.54.6-1.4-1.40.6-0.40.82.10.8-2.1-1.8-1.7-0.3-2.00.3-1.81.8-0.10.3-1.20.0-0.5-0.2-0.00.6
Total locomotion distance, NPP test1.21.64.0-1.2-0.91.40.31.62.01.3-1.9-1.3-1.90.5-1.90.7-1.71.71.00.7-0.80.90.60.61.00.2
Locomotion velocity, NPP test1.62.36.4-1.5-1.21.50.21.72.51.5-2.5-1.6-2.30.3-2.50.8-2.12.20.90.6-0.80.90.40.41.00.7
Intraocular pressure0.91.32.60.60.81.51.31.50.51.3-0.30.5-1.11.4-0.71.4-0.80.71.31.10.51.61.11.51.61.4
Delta distance traveled before/after self-admin1.01.03.11.31.0-1.10.1-1.1-1.7-1.01.70.81.4-0.11.6-0.41.4-1.4-0.6-0.0-0.4-0.9-0.50.0-0.7-0.1
Delta ambulatory time before/after self-admin1.01.32.71.00.7-1.4-0.4-1.5-1.7-1.31.60.71.6-0.61.6-0.71.5-1.4-1.1-0.5-0.4-1.3-0.8-0.4-1.20.1
Parametrial fat weight0.81.86.91.61.61.61.11.0-0.71.40.32.60.41.10.42.1-0.0-0.61.4-1.01.91.42.10.31.80.2
Pavlov. Cond. lever latency2.73.411.63.22.91.61.70.7-2.41.01.33.41.31.21.72.01.1-1.61.4-0.72.91.12.00.51.7-1.0
Pavlov. Cond. magazine entry latency1.62.16.6-1.9-1.7-1.8-1.5-1.11.3-1.0-0.6-2.6-0.5-1.4-0.8-1.2-0.80.9-1.60.4-2.5-1.2-2.1-1.1-1.70.8
Pavlov. Cond. change in total contacts0.91.02.4-1.1-1.1-1.3-1.0-1.00.4-1.10.1-1.50.0-1.0-0.1-1.5-0.10.2-1.10.2-1.5-0.9-1.4-0.7-1.30.8
Pavlov. Cond. index score2.43.09.9-2.8-2.5-1.9-1.8-1.02.0-1.1-1.1-3.2-0.9-1.5-1.3-1.8-1.01.2-1.60.5-2.8-1.1-2.1-0.9-1.60.9
Pavlov. Cond. latency score2.73.410.6-2.9-2.7-2.0-2.0-1.12.1-1.2-1.2-3.3-0.9-1.6-1.3-1.9-1.01.3-1.70.4-2.9-1.2-2.3-1.0-1.81.0
Pavlov. Cond. lever contacts2.22.69.2-3.0-2.8-1.4-1.7-0.72.1-1.1-1.1-2.9-1.0-1.3-1.3-2.0-0.81.2-1.20.3-2.2-0.9-1.5-0.6-1.30.8
Pavlov. Cond. magazine entry number1.21.54.71.71.51.51.30.9-1.20.80.62.20.51.20.81.10.7-0.91.4-0.42.11.01.80.91.4-0.7
Pavlov. Cond. intertrial magazine entries1.92.36.71.61.72.62.22.1-0.41.6-0.11.3-0.92.3-0.21.1-0.20.22.31.21.01.62.01.61.80.2
Pavlov. Cond. lever-magazine prob. diff.2.32.99.9-2.8-2.4-1.7-1.7-0.82.1-0.9-1.2-3.1-1.0-1.4-1.3-1.8-1.11.3-1.40.6-2.8-0.9-2.0-0.8-1.60.8
Pavlov. Cond. response bias1.72.16.6-2.4-2.2-1.6-1.6-0.91.6-1.0-0.8-2.6-0.7-1.3-1.0-1.5-0.71.0-1.40.3-2.1-1.0-1.8-0.9-1.40.7
Pavlov. Cond. lever latency0.91.22.8-0.7-1.0-0.7-1.2-1.2-0.8-1.30.70.41.1-1.40.7-1.71.3-0.9-1.0-1.61.1-1.6-0.5-1.4-1.3-0.2
Pavlov. Cond. magazine entry latency0.10.10.5-0.7-0.4-0.2-0.00.10.3-0.30.1-0.6-0.30.1-0.1-0.3-0.10.10.20.7-0.60.20.10.60.4-0.6
Pavlov. Cond. change in total contacts0.20.31.30.50.7-0.00.60.30.20.5-0.2-0.5-0.40.8-0.10.6-0.60.40.31.1-1.00.8-0.20.90.2-0.3
Pavlov. Cond. index score0.30.41.4-0.00.30.00.50.50.50.4-0.3-0.7-0.60.7-0.30.5-0.70.40.51.2-1.10.70.10.90.6-0.4
Pavlov. Cond. latency score0.20.31.10.10.4-0.00.50.40.40.4-0.2-0.5-0.40.7-0.20.5-0.60.30.41.1-1.00.70.10.90.6-0.5
Pavlov. Cond. lever contacts0.71.02.50.70.90.61.11.00.61.2-0.6-0.3-0.91.2-0.61.6-1.20.80.91.4-0.91.40.41.21.30.2
Pavlov. Cond. magazine entry number0.10.10.50.30.0-0.1-0.3-0.4-0.3-0.10.00.20.3-0.40.1-0.10.2-0.1-0.5-0.60.4-0.5-0.4-0.6-0.70.5
Pavlov. Cond. intertrial magazine entries1.32.04.9-1.1-1.6-1.4-1.8-1.50.4-1.0-0.5-1.10.2-1.9-0.5-1.70.00.5-2.1-1.2-0.7-1.9-2.2-1.8-2.11.3
Pavlov. Cond. lever-magazine prob. diff.0.30.41.3-0.00.30.00.50.50.50.4-0.3-0.6-0.60.7-0.30.6-0.70.40.51.1-1.10.80.21.00.7-0.5
Pavlov. Cond. response bias0.50.71.8-0.10.20.20.60.71.00.8-0.7-0.7-1.00.8-0.71.2-1.10.80.61.3-1.11.10.11.01.00.3
Time in closed arm before self-admin0.20.20.5-0.2-0.2-0.7-0.5-0.6-0.2-0.70.40.20.5-0.30.5-0.60.6-0.5-0.4-0.20.2-0.6-0.2-0.7-0.50.7
Time in closed arm after self-admin0.00.00.2-0.1-0.1-0.00.00.1-0.1-0.10.30.40.10.20.2-0.40.2-0.20.40.10.00.10.40.30.3-0.2
Time in open arm before self-admin0.20.31.2-0.5-0.3-0.3-0.00.00.4-0.1-0.1-1.1-0.6-0.2-0.5-0.1-0.30.6-0.20.9-1.0-0.2-0.80.6-0.3-0.0
Time in open arm after self-admin0.10.10.7-0.10.1-0.10.20.00.0-0.00.3-0.8-0.30.2-0.20.10.00.3-0.00.8-0.8-0.1-0.50.7-0.40.2
Bone: periosteal estimation2.04.17.6-0.7-0.9-2.7-2.1-2.8-1.8-2.72.21.02.7-2.12.3-2.72.7-2.4-1.9-2.31.4-2.2-0.9-1.1-1.5-1.1
Bone: periosteal perimeter1.12.04.6-1.0-1.2-2.2-1.8-2.0-0.7-1.91.20.11.6-1.81.1-2.01.5-1.2-1.6-1.50.4-1.5-1.1-1.0-0.9-0.8
Bone: post-yield work1.01.56.0-1.5-1.6-1.3-1.6-1.3-0.2-1.70.5-0.21.0-1.30.6-2.41.3-0.8-1.0-1.31.0-1.5-0.6-0.7-1.0-0.2
Progressive ratio test 1 active lever presses0.50.61.90.00.50.91.11.0-0.3-0.00.4-0.0-0.41.30.3-0.00.5-0.21.21.40.30.41.11.21.1-0.5
Progressive ratio test 1 breakpoint0.40.51.7-0.00.40.81.00.9-0.3-0.10.5-0.0-0.31.20.4-0.10.5-0.31.21.30.30.21.11.21.0-0.6
Progressive ratio test 1 inactive lever presses0.40.61.90.60.61.41.01.20.30.9-0.50.8-0.61.1-0.40.7-0.40.31.00.40.30.71.10.40.90.6
Progressive ratio test 2 active lever presses0.50.61.4-0.10.20.90.81.10.70.8-0.8-0.6-1.10.9-0.80.5-0.60.80.91.2-0.70.50.50.80.60.5
Progressive ratio test 2 breakpoint0.60.71.80.00.31.00.91.20.80.9-0.8-0.7-1.21.0-0.80.6-0.70.90.91.3-0.80.60.50.90.60.6
Progressive ratio test 2 inactive lever presses0.10.20.8-0.9-0.60.20.10.40.2-0.50.1-0.7-0.40.4-0.1-0.80.40.10.40.8-0.2-0.60.20.50.1-0.7
Incentive Sensitization - Responses0.40.62.1-0.5-0.6-0.2-0.40.01.10.4-1.1-1.0-0.8-0.3-1.10.2-0.91.1-0.50.2-1.4-0.2-0.8-0.3-0.51.4
Incentive Sensitization - Breakpoint0.50.72.6-0.4-0.50.0-0.20.21.20.7-1.3-0.9-1.0-0.1-1.30.4-1.11.3-0.30.3-1.4-0.0-0.7-0.2-0.31.6
Sum of active levers in priming session hrs 5-60.10.10.5-0.4-0.4-0.4-0.2-0.3-0.1-0.60.0-0.7-0.0-0.10.1-0.50.2-0.0-0.20.5-0.10.0-0.5-0.2-0.40.4
Progressive ratio1.32.16.62.62.0-0.30.4-0.9-2.5-0.01.72.52.20.12.00.41.4-2.0-0.2-1.61.60.10.6-0.40.2-0.6
Food seeking constrained by brief footshock0.50.61.50.91.00.71.10.9-0.40.70.50.7-0.31.00.10.80.10.11.11.20.61.00.81.10.90.4
Seeking ratio, punishment vs. effort0.71.03.6-1.7-1.30.0-0.10.61.5-0.2-1.0-1.9-1.60.0-1.3-0.3-0.81.40.21.6-1.0-0.3-0.60.3-0.30.4
Retroperitoneal fat weight0.10.61.90.30.51.20.71.00.11.0-0.21.0-0.30.8-0.31.2-0.20.11.1-0.10.61.11.40.61.20.6
Reaction time number correct0.50.93.21.81.61.11.30.7-1.00.90.51.60.21.20.40.80.4-0.31.00.21.10.40.90.60.6-0.2
Reaction time mean minus median0.51.13.8-2.0-1.9-0.9-1.2-0.51.4-0.8-0.9-1.9-0.7-0.8-0.9-0.8-1.20.8-1.00.2-1.2-0.5-1.1-0.5-0.10.6
Reaction time mean minus median AUC0.41.04.4-2.0-1.6-0.1-0.40.41.4-0.6-0.8-2.1-1.20.0-0.9-0.9-1.00.9-0.01.1-1.00.2-0.30.50.70.1
Reaction time num false alarms1.01.43.1-0.8-1.1-1.6-1.6-1.6-0.0-1.10.1-0.50.6-1.70.0-1.20.3-0.1-1.8-1.2-0.1-1.4-1.7-1.5-1.61.0
Reaction time num false alarms AUC1.42.15.3-0.7-1.2-2.1-2.0-2.1-0.4-1.40.2-0.51.1-2.10.3-1.40.5-0.3-2.3-1.6-0.2-1.8-2.2-1.9-2.10.7
Reaction time trials correct on left0.50.93.21.81.61.11.30.7-1.00.90.51.60.21.20.40.80.4-0.31.00.21.10.40.90.60.6-0.2
Reaction time trials on left0.40.83.11.81.61.01.20.7-1.00.90.41.60.21.20.50.70.4-0.40.90.21.10.40.90.60.6-0.2
Reaction time mean0.60.95.6-2.4-2.1-0.7-1.2-0.31.3-1.1-0.3-1.5-0.4-0.7-0.5-1.1-0.30.3-0.5-0.0-0.7-0.5-0.30.00.0-0.3
Reaction time mean AUC0.50.74.9-2.2-1.9-0.5-1.0-0.11.2-1.0-0.2-1.4-0.5-0.5-0.5-1.0-0.30.3-0.20.2-0.6-0.3-0.10.30.2-0.2
Median of all reaction times0.40.53.9-2.0-1.6-0.4-0.9-0.10.9-0.90.1-1.0-0.2-0.5-0.2-0.90.0-0.0-0.1-0.1-0.3-0.30.10.30.1-0.6
Reaction time omissions0.81.13.7-1.8-1.9-0.9-1.5-0.71.4-0.8-0.8-1.5-0.4-1.2-0.8-1.2-0.80.5-1.1-0.6-0.5-0.9-1.0-0.9-0.50.7
Reaction time false alarm rate2.23.06.6-1.6-2.0-2.5-2.4-2.30.2-1.80.1-1.50.8-2.50.0-1.80.3-0.1-2.6-1.4-0.8-1.8-2.5-2.0-2.30.8
Reaction time premature initiation rate0.10.20.60.10.30.10.20.1-0.2-0.10.40.80.40.30.6-0.20.5-0.60.4-0.10.80.00.70.10.00.7
Reaction time premature initiations0.40.83.11.21.30.60.80.4-1.00.40.81.70.70.91.00.10.8-0.90.8-0.11.50.21.20.40.20.4
Std. dev. reaction times0.81.54.9-2.2-2.1-1.5-1.6-1.01.0-1.6-0.3-2.0-0.2-1.2-0.3-1.6-0.40.3-1.4-0.0-1.3-1.1-1.4-0.5-0.60.1
Reaction time trials completed0.40.83.11.81.61.01.20.7-1.00.90.41.60.21.20.50.70.4-0.40.90.21.10.40.90.60.6-0.2
Reaction time trials AUC0.40.83.01.71.51.11.20.7-1.00.90.41.60.21.20.40.80.4-0.31.00.11.10.41.00.60.7-0.2
Run reversals in cocaine runway, females1.21.22.90.91.21.51.61.5-0.01.1-0.20.4-0.61.4-0.01.0-0.30.11.71.20.50.91.71.21.4-1.0
Run reversals in cocaine runway, males0.60.61.7-1.3-1.1-0.8-0.9-0.50.9-0.4-0.6-1.1-0.3-0.8-0.5-0.6-0.20.5-0.7-0.1-0.6-1.1-0.9-0.6-0.9-0.5
Latency to leave start box in cocaine runway0.50.52.7-1.6-1.5-0.7-1.1-0.50.7-0.70.1-0.7-0.1-0.8-0.4-1.10.00.2-0.5-0.5-0.0-0.4-0.5-0.5-0.60.8
Latency to leave start box in cocaine runway, F0.30.31.6-1.3-1.2-0.1-0.5-0.00.6-0.50.2-0.7-0.4-0.4-0.5-0.7-0.10.4-0.1-0.10.20.1-0.3-0.1-0.11.1
Latency to leave start box in cocaine runway, M0.40.30.9-0.8-0.8-0.8-1.0-0.70.1-0.4-0.0-0.10.4-0.70.1-0.80.2-0.2-0.6-0.9-0.0-0.6-0.2-0.7-0.8-0.7
Std. dev. time between licks in bursts3.64.911.0-2.8-2.9-3.2-3.3-2.80.3-2.60.3-1.31.2-3.10.3-2.60.9-0.5-2.9-2.0-1.0-2.4-2.5-2.6-2.9-0.1
Total sessions with >9 infusions0.50.62.70.71.00.71.30.8-0.60.00.6-0.3-0.31.30.50.30.2-0.21.11.60.10.60.61.20.8-0.2
Short access day 1 total inactive lever presses0.20.21.0-0.7-0.5-0.10.10.1-0.4-1.00.6-0.20.00.40.5-0.50.8-0.40.40.90.3-0.10.20.10.1-0.1
Short access day 10 total inactive lever presses0.71.74.2-1.1-1.6-0.8-1.7-1.11.2-0.2-1.3-0.3-0.1-1.6-1.2-0.3-0.91.0-1.8-1.9-0.4-1.4-1.8-2.1-1.21.5
Short access day 1 total infusions0.40.52.8-0.10.30.61.00.8-0.3-0.30.5-0.7-0.51.20.3-0.20.4-0.21.01.70.20.30.71.20.50.0
Short access day 10 total infusions0.81.02.90.50.71.41.51.40.20.7-0.3-0.5-1.01.6-0.40.8-0.50.51.41.7-0.41.00.81.11.31.2
Short access total infusions0.81.04.10.30.71.21.61.3-0.30.20.3-0.5-0.81.80.20.30.10.01.62.0-0.00.91.11.61.30.3
Short access day 1 locomotion0.40.51.7-1.0-0.90.1-0.40.11.0-0.1-0.9-1.3-0.7-0.3-0.8-0.2-0.70.8-0.40.1-0.4-0.2-0.6-0.3-0.41.3
Short access day 10 total locomotion2.03.76.9-0.2-0.6-2.2-1.9-2.6-1.9-2.41.90.82.6-1.92.1-1.72.1-2.2-2.0-2.31.7-2.2-1.2-2.0-1.8-1.8
Short access total locomotion0.50.61.7-0.4-0.4-0.6-0.5-0.8-0.8-1.31.10.11.0-0.51.1-0.91.1-1.1-0.5-0.61.1-0.9-0.2-0.4-0.4-0.9
One hour access (0.3 mA shock)1.21.44.6-1.1-1.00.1-0.50.41.80.9-2.1-1.7-1.4-0.3-1.80.3-1.61.7-0.40.2-1.7-0.3-0.8-0.7-0.61.2
Compulsive drug intake3.94.711.2-2.6-3.1-2.0-3.4-2.11.7-1.1-1.8-1.50.2-3.2-1.3-1.6-0.70.8-2.9-2.9-0.2-2.2-2.3-3.3-2.90.5
One hour access (shock baseline)1.62.46.51.11.71.82.32.1-0.01.5-0.3-0.1-1.32.4-0.41.5-0.70.72.32.6-1.01.71.52.02.00.4
Social response proportion1.01.12.5-0.1-0.4-1.1-0.8-1.3-1.1-1.51.60.71.5-0.61.3-1.41.5-1.4-0.7-1.10.7-1.1-0.3-0.3-0.8-1.0
Social responses0.91.12.80.0-0.4-1.5-1.2-1.7-0.9-1.31.20.61.5-0.91.1-1.10.9-1.1-1.4-1.40.5-1.2-1.0-0.9-0.6-0.3
Social time4.15.612.5-2.5-3.1-2.6-3.5-2.81.0-1.9-0.8-1.60.7-3.4-0.7-1.8-0.10.4-3.4-3.0-0.3-3.1-3.2-3.3-3.01.0
Soleus weight2.98.517.9-3.0-3.1-3.5-3.7-3.6-1.4-4.21.9-0.22.8-3.62.1-4.23.1-2.4-3.0-3.11.4-3.9-1.8-2.8-2.8-1.4
Bone: stiffness0.30.42.30.90.80.60.40.2-0.70.40.41.40.50.10.5-0.30.5-0.50.4-0.81.50.20.80.00.2-0.0
Tibialis anterior weight0.10.51.80.91.00.80.60.6-0.11.2-0.60.6-0.30.8-0.31.4-0.50.20.6-0.0-0.01.00.70.20.3-0.7
Time to tail flick, vehicle, before self-admin1.01.13.2-0.3-0.8-0.2-1.2-0.51.20.6-1.7-0.6-0.3-1.2-1.20.6-1.61.0-1.3-1.7-0.6-0.2-1.1-1.8-0.80.3
Time to tail flick, vehicle, after self-admin0.10.21.1-0.6-0.7-0.5-0.4-0.30.4-0.60.2-0.5-0.1-0.4-0.1-0.5-0.00.1-0.40.1-0.1-0.2-0.60.3-0.11.0
Time to tail flick, test, before self-admin0.50.52.10.40.2-0.2-0.2-0.20.50.8-1.3-0.5-0.4-0.4-0.80.7-1.00.9-0.8-0.3-1.4-0.1-1.1-0.9-0.40.9
Time to tail flick, test, after self-admin1.71.86.4-0.7-0.60.20.00.71.91.1-1.8-1.6-1.80.1-2.00.8-1.82.1-0.11.1-2.50.6-1.00.3-0.22.2
Delta time to tail flick, vehicle, before/after SA1.51.46.50.00.61.11.61.60.30.50.3-0.4-1.21.6-0.30.4-0.10.51.82.6-0.51.21.02.31.41.0
Delta time to tail flick, test, before/after SA0.70.71.6-0.5-0.30.90.41.11.30.9-0.9-0.5-1.20.6-1.10.6-1.01.00.80.7-0.41.00.60.80.70.7
Tibia length2.36.411.5-0.8-1.3-3.1-2.8-3.4-1.9-3.02.41.13.1-3.02.3-3.22.9-2.5-2.7-3.31.8-3.3-1.5-2.6-2.6-0.6
Ambulatory time before self-admin0.10.20.6-0.6-0.60.0-0.5-0.10.40.1-0.5-0.5-0.2-0.4-0.5-0.1-0.50.3-0.3-0.70.8-0.0-0.2-0.3-0.0-0.0
Ambulatory time after self-admin1.01.12.50.3-0.1-1.3-1.0-1.6-1.2-1.11.10.51.5-1.01.1-0.81.0-1.1-1.3-1.50.6-1.4-0.9-1.0-1.2-0.3
Bone: tissue strength0.50.51.50.40.50.70.80.6-0.6-0.10.80.70.21.10.60.40.6-0.61.00.50.90.71.11.21.2-0.3
Total heroin consumption0.50.63.8-0.5-0.7-0.8-1.0-0.90.2-0.4-0.5-0.30.2-0.8-0.3-0.5-0.20.2-1.2-1.0-0.4-0.6-1.2-1.0-1.01.9
Bone: trabecular number2.23.78.2-0.2-0.02.41.32.42.52.5-2.9-1.5-2.91.3-2.82.1-2.92.71.41.6-1.61.70.50.90.80.8
Bone: trabecular spacing2.53.48.60.70.4-1.9-0.8-2.0-2.7-2.32.91.82.8-0.82.9-1.62.9-2.8-0.9-1.31.9-1.3-0.10.0-0.2-1.1
Bone: trabecular thickness1.72.14.9-0.40.01.80.91.92.12.1-2.1-0.8-2.11.1-2.10.8-2.21.91.21.0-1.21.50.80.60.70.5
Bone: trabecular tissue density0.20.30.90.20.3-0.8-0.0-0.5-0.5-0.61.0-0.10.4-0.10.6-0.90.5-0.4-0.30.7-0.1-0.7-0.6-0.0-0.40.6
Water consumed over 24 hours0.30.40.9-0.7-0.7-0.9-0.9-0.80.0-0.80.2-0.20.5-0.90.3-0.90.4-0.4-0.8-0.70.1-0.8-0.5-0.8-0.5-0.3
Number of responses in last shaping day2.12.35.7-0.8-0.8-2.0-1.3-1.8-1.6-2.42.0-0.41.7-1.21.8-2.22.1-1.8-1.1-0.40.5-1.8-0.7-0.5-1.6-1.2