Hub : Genes

LOC134483348

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	RMTg	gene expression	LOC134483348	0.33	0.19	7.5e-03	0.04	0.05	0.04	0.05	2.8e-02	1.7e-02	3.7e-02	2.1e-02
2	Brain	intron excision ratio	chr19_50328051_50357042	0.18	0.16	4.5e-06	0.07	0.06	0.07	0.06	4.2e-07	6.7e-06	1.7e-07	2.7e-06
3	Liver	gene expression	LOC134483348	0.04	0.03	3.2e-05	0.04	0.04	0.05	0.04	5.1e-05	7.5e-05	7.5e-06	2.8e-05
4	Brain	intron excision ratio	chr19_50342955_50357042	0.64	0.08	2.6e-05	0.04	0.06	0.07	0.03	7.1e-05	4.9e-06	7.4e-07	4.1e-04
5	IC	intron excision ratio	chr19_50328051_50357042	0.06	0.04	6.4e-03	0.01	0.03	0.05	0.01	1.1e-01	2.4e-02	3.0e-03	1.3e-01
6	PL	intron excision ratio	chr19_50328051_50357042	0.06	0.06	1.7e-04	0.02	0.02	0.02	0.01	4.8e-03	1.3e-03	6.7e-03	8.1e-03
7	NAcc	intron excision ratio	chr19_50328051_50357042	0.03	0.04	9.9e-03	0.01	0.01	0.01	0.01	4.0e-02	8.6e-03	2.8e-02	2.7e-02
8	pVTA	intron excision ratio	chr19_50342955_50357042	0.04	0.03	2.9e-04	0.01	0.04	0.02	0.02	2.1e-02	4.7e-04	6.5e-03	6.6e-03
9	IC	intron excision ratio	chr19_50342955_50357042	0.07	0.05	1.8e-03	0.03	0.06	0.04	0.05	1.6e-02	2.1e-03	1.2e-02	5.0e-03
10	OFC	intron excision ratio	chr19_50328051_50342690	0.15	0.13	8.4e-03	0.04	0.05	0.01	0.04	4.1e-02	2.8e-02	1.7e-01	4.8e-02
11	PL	intron excision ratio	chr19_50342955_50357042	0.03	0.03	1.4e-04	0.02	0.02	0.01	0.01	6.7e-03	1.6e-03	5.2e-02	1.6e-02
12	Brain	gene expression	LOC134483348	0.04	0.04	1.4e-03	0.02	0.01	-0	0.01	1.1e-02	1.9e-02	4.8e-01	7.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Bone: apparent density	0.1	0.2	0.6	-0.6	0.8	0.1	-0.8	-0.0	0.4	0.4	-0.3	-0.3	-0.3	-0.2	0.1
Area under the delay curve	0.2	0.2	1.2	0.1	-1.1	-0.2	0.9	0.1	0.1	0.1	-0.1	0.0	-0.0	-0.1	0.4
BMI with tail	0.1	0.4	1.4	-0.4	1.0	0.8	-1.2	0.7	0.5	0.6	-0.4	-0.4	-0.4	-0.4	0.1
BMI without tail	0.0	0.0	0.2	0.4	-0.2	0.2	-0.1	0.3	0.0	0.0	-0.1	-0.0	-0.1	-0.2	0.3
Body weight	0.4	1.9	4.9	-1.1	1.9	1.7	-2.2	1.3	1.1	1.0	-1.1	-1.2	-1.2	-1.1	0.7
Weight adjusted by age	0.1	0.1	0.6	0.0	-0.3	-0.6	-0.2	-0.8	-0.1	-0.1	-0.0	-0.1	-0.1	-0.0	0.2
Bone surface	1.3	2.4	3.8	-1.9	1.9	1.3	-1.8	1.3	1.5	1.5	-1.5	-1.6	-1.5	-1.4	1.3
Bone volume	1.1	1.9	3.5	-1.7	1.9	1.2	-1.8	0.9	1.3	1.3	-1.3	-1.4	-1.3	-1.2	1.1
Breakpoint value in progressive ratio session	2.0	2.4	4.1	1.2	-0.8	-1.7	0.8	-2.0	-1.6	-1.5	1.6	1.6	1.6	1.7	-2.0
Number of licking bursts	0.5	0.8	1.1	-1.1	0.7	0.7	-0.6	0.8	1.0	0.9	-1.0	-1.0	-0.9	-0.9	1.0
Context. condit. distance diff. score	0.1	0.1	0.3	0.0	-0.3	-0.5	0.3	-0.3	-0.3	-0.5	0.3	0.2	0.3	0.4	0.2
Locomotion velocity, session 1	0.1	0.1	0.3	-0.1	-0.1	0.4	0.5	0.4	0.4	0.4	-0.3	-0.2	-0.3	-0.4	0.4
Locomotion distance, session 1	0.1	0.2	0.4	0.6	-0.5	-0.3	0.4	-0.3	-0.4	-0.5	0.3	0.3	0.3	0.3	-0.2
Locomotion velocity, session 2	0.7	0.8	1.7	1.3	-0.6	-0.9	0.3	-0.9	-1.2	-1.3	1.0	0.9	0.9	0.9	-0.3
Locomotion distance, session 2	0.2	0.2	0.5	0.7	-0.5	-0.3	0.4	-0.4	-0.6	-0.7	0.4	0.4	0.3	0.4	0.1
Locomotion velocity, session 3	0.4	0.4	1.1	0.5	-1.0	-0.8	1.1	-0.6	-0.4	-0.3	0.5	0.6	0.5	0.5	-0.5
Locomotion distance, session 3	0.2	0.2	0.7	0.2	-0.8	-0.4	0.7	-0.2	-0.3	-0.4	0.3	0.2	0.2	0.3	0.1
Stereotopy head waving bouts, day 3	0.1	0.1	0.3	-0.1	0.2	0.4	-0.1	0.5	0.4	0.4	-0.4	-0.3	-0.4	-0.4	0.4
Stereotopy head waving duration, day 3	0.6	0.7	1.5	-0.8	1.2	0.9	-1.1	0.8	0.8	0.8	-0.8	-0.8	-0.8	-0.8	0.4
Locomotion velocity, session 7	0.1	0.1	0.2	-0.2	0.2	-0.3	-0.1	-0.4	-0.1	-0.1	0.2	0.1	0.2	0.2	-0.5
Locomotion distance, session 7	0.1	0.1	0.5	-0.0	-0.6	-0.5	0.7	-0.3	-0.3	-0.3	0.3	0.2	0.3	0.3	-0.3
Stereotopy head waving bouts, day 7	0.2	0.2	0.6	-0.8	0.5	0.3	-0.2	0.4	0.6	0.7	-0.4	-0.4	-0.4	-0.4	0.2
Stereotopy head waving duration, day 7	0.6	0.7	1.4	-1.1	0.8	0.8	-0.3	0.8	1.1	1.2	-0.9	-0.8	-0.7	-0.8	0.5
Locomotion velocity, session 8	0.1	0.1	0.6	-0.2	0.3	-0.4	-0.2	-0.6	0.0	0.1	0.1	0.2	0.2	0.2	-0.7
Locomotion distance, session 8	0.4	0.6	0.9	0.7	-0.9	-1.0	0.9	-0.7	-0.8	-1.0	0.8	0.7	0.8	0.8	-0.1
Degree of sensitization distance	0.0	0.0	0.1	-0.2	0.1	0.1	0.0	0.2	0.1	0.2	-0.1	-0.1	-0.1	-0.1	0.1
Degree of sensitization stereotypy	0.3	0.4	0.7	-0.8	0.6	0.5	-0.4	0.6	0.8	0.8	-0.6	-0.5	-0.5	-0.5	0.5
Conditioned locomotion	1.7	1.9	2.6	-1.6	1.5	1.4	-1.1	1.3	1.3	1.2	-1.4	-1.6	-1.5	-1.4	1.2
Cocaine response after cond. corrected	0.6	0.7	1.5	-0.8	0.7	1.0	-0.6	0.9	1.1	1.2	-0.8	-0.6	-0.7	-0.9	0.4
Cocaine response after cond. not corrected	0.1	0.1	0.5	-0.2	0.1	0.5	-0.1	0.5	0.6	0.7	-0.3	-0.1	-0.2	-0.4	0.2
Cocaine response before conditioning	1.1	1.4	2.0	1.4	-1.4	-1.2	1.3	-0.8	-1.2	-1.2	1.2	1.2	1.2	1.1	-0.4
Saline control response	4.2	5.6	7.3	-2.2	2.2	2.7	-1.9	2.5	2.3	2.2	-2.5	-2.5	-2.5	-2.5	2.4
Bone: connectivity density	0.0	0.1	0.2	-0.1	0.3	-0.4	-0.3	-0.4	-0.1	-0.1	0.2	0.2	0.3	0.3	-0.3
Bone: cortical apparent density	1.0	1.4	3.5	0.6	-1.7	-1.3	1.9	-1.1	-0.8	-0.6	1.0	1.1	1.1	1.1	-1.4
Bone: cortical area	0.3	0.5	1.1	-0.8	0.9	0.6	-1.0	0.4	0.6	0.6	-0.6	-0.7	-0.7	-0.6	0.6
Bone: cortical porosity	0.4	0.4	0.7	0.6	-0.6	-0.4	0.8	-0.7	-0.7	-0.8	0.6	0.5	0.5	0.6	-0.3
Bone: cortical porosity	0.3	0.4	1.1	0.5	-0.8	-0.4	1.0	-0.7	-0.6	-0.7	0.5	0.4	0.4	0.5	-0.2
Bone: cortical thickness	0.2	0.3	1.0	-0.7	0.9	0.3	-1.0	0.0	0.4	0.5	-0.4	-0.4	-0.3	-0.3	-0.2
Bone: cortical thickness	0.1	0.1	0.7	-0.1	0.6	0.1	-0.9	-0.2	-0.4	-0.5	0.1	-0.1	0.0	0.2	0.1
Bone: cortical tissue density	1.1	1.5	3.8	0.7	-1.8	-1.3	2.0	-1.2	-0.8	-0.6	1.0	1.1	1.1	1.1	-1.4
Condit. Reinf. active minus inactive responses	4.4	4.9	7.7	2.1	-2.6	-2.4	2.8	-2.3	-2.0	-2.0	2.1	2.2	2.1	2.1	-1.7
Condit. Reinf. active-inactive response ratio	3.8	4.0	6.5	1.8	-2.4	-2.1	2.5	-1.9	-1.8	-1.7	2.0	2.0	2.0	2.0	-1.6
Condit. Reinf. active responses	3.2	4.0	6.3	2.0	-2.5	-2.2	2.5	-2.0	-1.9	-1.9	1.9	1.9	1.9	1.9	-1.1
Condit. Reinf. inactive responses	0.2	0.3	0.4	0.5	-0.6	-0.5	0.5	-0.5	-0.6	-0.6	0.5	0.5	0.5	0.5	-0.1
Incentive salience index mean	2.4	3.0	5.2	1.6	-2.0	-1.9	2.3	-1.8	-1.6	-1.6	1.6	1.6	1.6	1.6	-1.2
Condit. Reinf. lever presses	0.2	0.3	0.8	0.3	-0.4	-0.6	0.9	-0.7	-0.4	-0.4	0.4	0.4	0.4	0.4	-0.3
Condit. Reinf. active minus inactive responses	0.7	0.9	1.3	-1.0	0.4	1.0	-0.8	0.8	1.0	0.9	-1.0	-1.0	-1.0	-1.0	1.1
Condit. Reinf. active-inactive response ratio	0.6	0.7	1.0	-0.9	0.7	0.9	-1.0	0.8	0.9	0.9	-0.8	-0.8	-0.8	-0.8	0.8
Condit. Reinf. active responses	0.3	0.5	0.9	-0.7	0.3	0.7	-0.8	0.6	0.6	0.5	-0.7	-0.8	-0.7	-0.7	0.9
Condit. Reinf. inactive responses	0.2	0.3	0.5	0.6	-0.6	-0.5	0.2	-0.5	-0.6	-0.7	0.5	0.4	0.4	0.5	-0.2
Condit. Reinf. lever presses	2.5	3.4	5.0	1.8	-1.0	-2.0	0.3	-2.1	-2.1	-2.2	2.0	1.8	1.9	2.0	-1.8
Condit. Reinf. lever reinforcers received	0.0	0.1	0.4	-0.2	0.1	0.2	-0.7	0.0	0.1	-0.0	-0.2	-0.3	-0.2	-0.2	0.4
Conditioned reinforcement - actives	0.6	1.0	2.3	1.5	-1.4	-0.6	1.3	-0.5	-1.1	-1.1	1.0	1.0	0.9	0.8	-0.3
Conditioned reinforcement - inactives	0.2	0.3	1.1	-1.0	0.3	0.4	0.2	0.4	0.7	0.9	-0.4	-0.2	-0.2	-0.2	-0.0
Conditioned locomotion	0.8	1.1	1.8	-1.4	0.8	0.9	-0.8	1.2	1.2	1.2	-1.0	-0.9	-0.9	-0.9	1.1
Patch foraging indifference point 0 sec	2.9	5.3	6.8	-2.2	2.0	2.6	-2.0	2.5	2.2	2.1	-2.3	-2.4	-2.4	-2.3	2.6
Patch foraging indifference point AUC	1.9	2.7	4.6	-1.6	1.9	1.6	-2.1	1.8	1.4	1.2	-1.5	-1.7	-1.6	-1.5	1.6
Delay disc. indifference point, 0s delay	0.5	0.6	0.9	1.0	-0.9	-0.8	0.8	-0.6	-0.7	-0.6	0.7	0.8	0.8	0.7	-0.7
Delay disc. indifference point, 16s delay	0.2	0.3	1.2	0.2	-0.6	0.5	0.4	0.5	0.3	0.2	-0.4	-0.4	-0.5	-0.5	1.1
Delay disc. indifference point, 2s delay	0.2	0.3	1.1	-1.0	0.0	0.2	0.1	0.4	0.8	0.8	-0.5	-0.4	-0.3	-0.4	0.3
Delay disc. indifference point, 24s delay	0.0	0.1	0.2	0.1	-0.3	0.3	0.5	0.3	-0.0	-0.1	-0.0	-0.1	-0.1	-0.1	0.4
Delay disc. indifference point, 4s delay	0.3	0.3	0.7	0.2	-0.9	-0.6	0.6	-0.4	-0.3	-0.2	0.5	0.5	0.6	0.5	-0.8
Delay disc. indifference point, 8s delay	0.3	0.4	2.4	0.1	-1.5	-0.5	1.4	-0.3	0.1	0.1	-0.1	0.0	-0.1	-0.1	0.4
Indifference point function ln k	0.3	0.5	2.1	0.5	-1.3	-0.4	1.5	-0.3	-0.3	-0.3	0.5	0.7	0.6	0.5	-0.5
Indifference point function log k	0.3	0.5	2.1	0.5	-1.3	-0.4	1.5	-0.3	-0.3	-0.3	0.5	0.7	0.6	0.5	-0.5
Patch foraging total patch changes 0 sec	2.8	5.2	6.7	-2.2	2.0	2.5	-2.1	2.4	2.2	2.0	-2.3	-2.4	-2.4	-2.3	2.6
Patch foraging total patch changes 12 sec	2.6	3.4	5.2	-1.8	1.8	1.8	-1.6	1.9	1.7	1.6	-1.9	-2.0	-1.9	-1.9	2.3
Patch foraging total patch changes 18 sec	2.5	3.8	5.1	-1.9	2.0	2.0	-2.3	2.0	1.7	1.4	-1.9	-2.0	-2.0	-1.8	2.2
Patch foraging total patch changes 24 sec	0.2	0.3	0.7	-0.8	0.8	0.0	-0.9	0.0	0.4	0.3	-0.5	-0.6	-0.5	-0.4	0.3
Patch foraging total patch changes 6 sec	2.0	3.0	3.7	-1.8	1.7	1.6	-1.9	1.7	1.7	1.6	-1.7	-1.8	-1.7	-1.7	1.8
Patch foraging time to switch 0 sec	0.8	1.7	2.3	1.2	-1.1	-1.5	1.4	-1.5	-1.2	-1.1	1.3	1.3	1.3	1.2	-1.3
Patch foraging water rate 0 sec	1.6	3.3	5.1	-1.5	2.1	2.1	-2.3	2.0	1.6	1.5	-1.7	-1.7	-1.8	-1.7	1.7
Patch foraging water rate 12 sec	0.2	0.4	2.2	-0.6	0.7	0.5	-1.5	0.6	0.5	0.4	-0.4	-0.4	-0.4	-0.4	0.7
Patch foraging water rate 18 sec	0.1	0.1	0.4	-0.6	0.0	0.0	-0.6	0.3	0.2	0.1	-0.2	-0.2	-0.1	-0.1	0.6
Patch foraging water rate 24 sec	0.0	0.1	0.4	0.1	-0.1	0.2	-0.3	0.2	0.0	-0.1	-0.1	-0.1	-0.2	-0.2	0.6
Patch foraging water rate 6 sec	0.8	1.1	2.6	-1.4	1.2	1.0	-1.6	0.9	1.0	0.9	-0.9	-1.0	-0.9	-0.8	0.7
Seeking ratio, delayed vs. immediate footshock	2.4	2.9	3.9	-1.9	1.0	1.7	-0.5	1.7	2.0	2.0	-1.9	-1.8	-1.8	-1.9	1.7
Distance traveled before self-admin	0.7	0.9	5.8	-2.4	1.0	0.0	-0.7	0.3	1.0	1.1	-0.6	-0.7	-0.5	-0.3	-0.0
Distance traveled after self-admin	0.1	0.2	0.7	-0.7	-0.2	-0.3	0.8	-0.0	0.4	0.4	-0.3	-0.3	-0.2	-0.2	0.1
Extensor digitorum longus weight	0.8	3.0	4.7	1.7	-1.0	-1.8	0.9	-1.9	-2.1	-2.2	1.9	1.7	1.8	1.9	-1.5
Bone: elastic displacement	1.8	2.1	2.5	-1.4	1.2	1.6	-1.4	1.6	1.5	1.6	-1.5	-1.4	-1.5	-1.5	1.2
Bone: elastic work	0.7	0.9	1.8	-1.0	1.1	0.9	-1.4	1.0	0.9	1.0	-0.9	-0.9	-0.9	-0.9	0.7
Bone: endosteal estimation	0.1	0.2	0.5	-0.2	-0.3	0.5	0.6	0.6	0.2	0.2	-0.3	-0.4	-0.4	-0.4	0.7
Bone: endosteal perimeter	0.2	0.3	1.5	-0.5	0.3	0.6	-0.4	0.6	0.4	0.2	-0.5	-0.6	-0.6	-0.5	1.2
Epididymis fat weight	2.1	7.3	10.8	-2.8	2.4	2.6	-3.0	3.0	2.5	2.3	-2.6	-2.7	-2.6	-2.5	3.3
Delta time in closed arm before/after self-admin	0.2	0.2	0.4	0.0	-0.3	0.3	0.5	0.5	0.4	0.3	-0.4	-0.4	-0.5	-0.5	0.7
Delta time in open arm before/after self-admin	0.2	0.2	0.7	-0.7	-0.1	-0.7	0.2	-0.4	0.2	0.3	0.2	0.3	0.4	0.4	-0.9
Diff in mean of infusions in LGA sessions	0.6	0.7	1.6	0.4	0.1	-1.0	-0.2	-1.3	-0.8	-0.8	0.8	0.8	0.9	1.0	-1.3
Delay discount exponential model param	0.2	0.2	1.2	-0.2	1.1	0.3	-1.0	0.0	-0.0	-0.0	-0.0	-0.1	-0.1	-0.0	-0.2
Extinction: sum of active levers before priming	0.6	0.6	1.3	1.1	0.0	-0.2	-0.6	-0.6	-1.0	-1.0	0.9	0.9	0.9	0.9	-0.7
Active lever presses in extinction session 6	0.1	0.1	0.3	0.2	-0.4	0.3	0.5	0.0	-0.0	-0.0	-0.1	-0.1	-0.2	-0.2	0.1
Bone: final force	1.0	1.6	2.3	1.2	-1.0	-1.4	0.8	-1.5	-1.4	-1.4	1.3	1.2	1.2	1.3	-1.2
Bone: final moment	0.4	0.7	1.0	0.8	-0.7	-0.9	0.7	-1.0	-0.9	-0.9	0.8	0.8	0.8	0.8	-0.8
Food consumed during 24 hour testing period	0.2	0.3	1.8	-0.1	-0.2	0.5	-0.3	0.8	0.2	-0.1	-0.4	-0.6	-0.6	-0.5	1.3
Glucose	1.5	2.4	2.9	1.5	-1.7	-1.7	1.5	-1.5	-1.4	-1.2	1.5	1.7	1.6	1.5	-1.6
Heart weight	0.0	0.0	0.3	-0.0	-0.1	0.2	0.1	0.0	0.1	0.2	0.1	0.1	0.1	0.1	-0.6
Delay discount hyperbolic model param	0.2	0.3	1.5	-0.2	1.2	0.4	-1.1	0.2	0.0	0.0	-0.2	-0.2	-0.2	-0.1	-0.0
Intermittent access intake day 1-15 change	1.1	2.3	4.3	2.1	-1.8	-1.2	1.4	-1.2	-1.7	-1.7	1.6	1.5	1.5	1.4	-0.9
Intermittent access intake escalation	1.3	2.6	4.4	2.1	-1.9	-1.4	1.6	-1.3	-1.7	-1.7	1.6	1.6	1.6	1.5	-1.0
Intermittent access intake escalation 2	1.0	1.1	2.4	1.5	-1.4	-0.6	1.2	-0.7	-1.1	-1.1	1.0	1.0	1.0	0.9	-0.5
Intermitt. access day 1 inactive lever presses	0.1	0.2	1.1	0.5	-0.8	0.2	1.0	0.2	-0.0	0.0	0.0	0.1	0.1	-0.1	0.4
Intermitt. access day 15 inactive lever presses	0.1	0.1	0.3	-0.3	-0.3	-0.5	0.3	-0.3	-0.1	0.0	0.3	0.4	0.5	0.4	-0.3
Intermitt. access escalation Index	0.3	0.4	0.5	-0.4	0.5	0.3	-0.7	0.6	0.6	0.7	-0.7	-0.6	-0.7	-0.7	0.6
Intermittent access day 1 total infusions	0.1	0.2	0.8	0.8	-0.6	0.4	0.9	0.5	0.1	0.2	-0.1	0.1	-0.1	-0.3	0.5
Intermittent access day 15 total infusions	1.5	2.2	5.7	2.4	-2.2	-1.0	1.9	-0.7	-1.4	-1.4	1.4	1.5	1.3	1.1	-0.4
Intermittent access terminal intake (last 3 days)	2.4	3.2	7.2	2.7	-2.3	-1.1	2.2	-1.0	-1.8	-1.8	1.7	1.9	1.7	1.5	-0.7
Intermittent access total infusions	1.9	2.2	5.9	2.4	-2.0	-0.8	1.8	-0.7	-1.5	-1.5	1.4	1.5	1.3	1.2	-0.5
Intermittent access day 1 locomotion	1.6	2.0	3.6	-0.8	0.4	1.5	-0.1	1.8	1.6	1.6	-1.5	-1.3	-1.5	-1.6	1.9
Intermittent access day 15 total locomotion	0.4	0.7	1.5	-0.5	0.0	0.9	-0.0	1.2	1.0	1.0	-0.8	-0.6	-0.7	-0.9	1.2
Intermittent access total locomotion	0.3	0.3	0.7	-0.1	-0.3	0.6	0.6	0.8	0.7	0.8	-0.5	-0.2	-0.4	-0.6	0.6
Intermittent access standard deviation	0.2	0.4	0.8	-0.6	0.6	0.9	-0.3	0.8	0.6	0.7	-0.5	-0.5	-0.5	-0.6	0.6
Left kidney weight	1.6	7.2	9.7	2.2	-1.7	-2.9	1.0	-3.0	-3.0	-3.1	2.9	2.7	2.9	3.1	-2.8
Right kidney weight	1.6	7.3	10.5	2.2	-1.4	-2.9	0.5	-3.1	-3.1	-3.2	3.0	2.7	3.0	3.2	-2.7
Cocaine induced anxiety	3.1	4.4	6.6	-2.1	2.6	2.3	-2.5	2.0	2.1	2.2	-2.0	-1.9	-1.9	-1.9	1.2
Post-drug Anxiety	0.8	0.8	1.5	-0.9	1.0	1.1	-1.2	0.9	1.0	1.0	-0.8	-0.7	-0.8	-0.8	0.4
Baseline Anxiety	1.9	2.3	5.6	1.7	-2.4	-1.5	2.0	-1.0	-1.4	-1.5	1.3	1.3	1.3	1.2	-0.4
Tail length	0.0	0.1	0.3	0.5	-0.3	0.2	0.2	0.1	-0.2	-0.3	-0.1	-0.1	-0.2	-0.2	0.5
Length with tail	0.1	0.6	2.0	-0.6	1.2	0.9	-1.4	0.6	0.4	0.2	-0.6	-0.8	-0.7	-0.6	0.6
Length without tail	0.6	2.0	5.0	-1.3	1.9	1.7	-2.2	1.4	1.1	1.0	-1.2	-1.3	-1.2	-1.1	1.0
Times rat made contact with spout	1.1	1.3	2.1	-1.0	0.5	1.1	-0.4	1.0	1.1	1.0	-1.3	-1.4	-1.4	-1.3	1.4
Lifetime Intake	1.6	1.9	5.2	2.3	-1.8	-0.9	1.6	-0.7	-1.4	-1.4	1.3	1.4	1.2	1.0	-0.4
Liver weight, left	0.3	0.4	1.5	-0.8	1.2	0.3	-1.0	0.3	0.5	0.6	-0.6	-0.6	-0.5	-0.5	-0.0
Liver weight, right	0.5	0.9	2.7	-0.6	1.4	1.1	-1.6	0.9	0.6	0.5	-0.8	-0.9	-0.9	-0.8	0.8
Locomotor activity	2.7	4.2	6.4	-2.4	2.5	2.0	-2.5	1.9	2.0	1.9	-2.0	-2.1	-2.0	-1.9	1.2
Locomotor testing distance	2.1	3.8	4.7	-2.0	2.1	2.0	-2.2	1.8	1.9	1.9	-2.0	-2.0	-2.0	-1.9	1.5
Locomotor testing rearing	0.4	0.8	2.8	-1.1	1.5	0.7	-1.7	0.5	0.6	0.6	-0.6	-0.6	-0.6	-0.5	0.0
Locomotion in novel chamber	2.4	3.1	3.8	-1.9	1.3	1.8	-1.4	1.9	1.9	1.9	-1.8	-1.7	-1.7	-1.8	1.6
Locomotion in novel chamber post-restriction	1.7	2.8	3.8	-1.2	1.2	1.9	-1.4	1.9	1.6	1.5	-1.7	-1.7	-1.8	-1.9	1.9
Fecal boli incidents, locomotor time 1	0.9	1.3	3.3	-0.3	1.3	1.0	-1.8	1.0	0.6	0.5	-1.1	-1.2	-1.3	-1.2	1.3
Change in fecal boli incidents, locomotor task	0.4	0.4	0.6	0.6	-0.7	-0.5	0.7	-0.3	-0.6	-0.6	0.7	0.8	0.8	0.8	-0.6
Time >=10cm from walls, locomotor time 1	0.3	0.4	1.1	0.1	-0.1	0.5	0.0	0.6	0.4	0.4	-0.7	-0.7	-0.8	-0.8	1.0
Bouts of movement, locomotor time 1	0.2	0.2	0.5	0.1	0.7	0.7	-0.5	0.4	0.3	0.4	-0.3	-0.3	-0.3	-0.4	-0.1
Total resting periods, locomotor time 1	0.0	0.0	0.1	0.4	0.3	0.3	0.0	0.2	0.0	0.1	-0.0	0.0	-0.0	-0.1	-0.3
Rest time, locomotor task time 1	0.1	0.1	0.7	0.6	0.4	-0.2	0.1	-0.1	-0.2	0.0	0.2	0.4	0.3	0.1	-0.8
Distance moved, locomotor task time 1	0.1	0.2	0.6	-0.6	-0.2	0.5	-0.1	0.3	0.4	0.3	-0.4	-0.4	-0.4	-0.3	0.8
Vertical activity count, locomotor time 1	0.5	1.2	2.9	-0.9	0.4	1.4	-1.0	1.3	0.8	0.6	-1.0	-1.1	-1.1	-1.0	1.7
Time >=10cm from walls, locomotor time 2	0.3	0.4	0.8	0.8	-0.4	-0.6	0.3	-0.9	-0.7	-0.7	0.6	0.6	0.6	0.6	-0.8
Bouts of movement, locomotor time 2	0.5	0.9	1.4	1.0	-0.8	-0.6	1.0	-0.8	-0.9	-0.9	0.9	1.0	0.9	0.9	-1.2
Total resting periods, locomotor time 2	0.6	1.1	1.8	1.1	-0.8	-0.8	1.0	-0.9	-1.1	-1.0	1.1	1.1	1.1	1.1	-1.3
Rest time, locomotor task time 2	0.5	0.6	2.1	1.4	-0.6	-0.5	0.6	-0.5	-1.0	-0.9	0.8	0.8	0.7	0.6	-0.7
Distance moved, locomotor task time 2	0.7	0.8	2.6	-1.6	0.9	0.7	-0.9	0.6	1.1	1.1	-0.8	-0.8	-0.7	-0.6	0.4
Vertical activity count, locomotor time 2	1.1	1.5	2.5	-1.6	1.1	1.3	-1.3	1.2	1.2	1.1	-1.1	-1.2	-1.1	-1.1	1.0
Light reinforcement 1	2.3	5.6	7.5	-2.7	2.6	2.3	-2.7	2.2	2.2	2.1	-2.3	-2.4	-2.3	-2.1	2.3
Light reinforcement 2	2.2	3.3	4.5	-2.1	1.4	1.7	-1.3	1.8	1.9	1.8	-1.9	-1.9	-1.9	-1.9	2.1
Bone: marrow area	0.1	0.2	0.5	-0.1	-0.4	0.4	0.7	0.5	0.2	0.1	-0.3	-0.3	-0.3	-0.3	0.6
Bone: maximum diameter	0.4	0.7	1.3	-0.8	0.6	0.9	-0.8	0.9	0.8	0.7	-0.9	-0.9	-0.9	-0.9	1.1
Bone: maximum force	0.3	0.5	0.9	0.5	-0.4	-0.9	0.3	-0.9	-0.7	-0.7	0.7	0.7	0.7	0.7	-0.8
Bone: maximum moment	0.0	0.1	0.2	0.1	-0.2	-0.4	0.2	-0.4	-0.2	-0.2	0.2	0.2	0.3	0.3	-0.4
Mean time between licks in bursts	0.1	0.2	0.9	-0.3	-1.0	-0.1	0.6	0.0	0.2	0.1	-0.1	-0.1	-0.1	-0.1	0.7
Mean num. licks in bursts	0.0	0.0	0.1	0.3	-0.3	0.1	0.3	0.0	-0.2	-0.2	0.0	-0.0	-0.0	-0.0	0.1
Cd content in liver	0.1	0.1	0.4	-0.1	0.3	-0.1	-0.4	-0.0	-0.2	-0.1	0.3	0.3	0.3	0.3	-0.6
Co content in liver	0.0	0.0	0.1	0.3	0.0	0.1	-0.3	0.0	-0.3	-0.3	0.2	0.2	0.2	0.2	-0.3
Cu content in liver	0.7	0.8	1.5	1.2	-0.5	-0.7	0.3	-0.6	-1.1	-1.2	1.0	1.0	1.0	1.0	-0.6
Fe content in liver	2.3	2.8	5.1	-1.4	2.2	1.7	-2.3	1.8	1.5	1.5	-1.6	-1.6	-1.6	-1.6	1.3
K content in liver	0.3	0.3	1.7	0.6	-1.0	-0.1	1.3	-0.1	-0.3	-0.3	0.3	0.3	0.3	0.2	0.1
Mg content in liver	0.4	0.4	0.8	-0.4	0.0	0.9	0.1	0.8	0.7	0.6	-0.7	-0.7	-0.7	-0.8	0.8
Mn content in liver	0.6	0.7	1.1	-0.9	-0.2	0.8	0.5	0.5	1.0	1.1	-0.9	-0.8	-0.8	-0.9	0.8
Na content in liver	0.1	0.1	0.9	0.2	-0.6	0.0	0.9	0.3	0.1	0.2	-0.0	0.1	-0.0	-0.1	-0.0
Rb content in liver	0.2	0.2	0.5	0.7	-0.4	-0.2	0.2	-0.5	-0.5	-0.5	0.5	0.5	0.5	0.4	-0.6
Se content in liver	0.1	0.2	0.5	0.1	-0.7	-0.4	0.6	-0.6	-0.3	-0.3	0.3	0.2	0.2	0.3	-0.1
Sr content in liver	0.8	0.7	1.1	-1.0	0.5	0.8	-0.6	0.5	0.9	0.9	-0.9	-1.0	-0.9	-0.9	0.8
Zn content in liver	1.7	1.9	2.7	1.6	-1.5	-1.2	1.3	-1.0	-1.6	-1.6	1.5	1.4	1.4	1.4	-1.0
Bone: minimum diameter	0.1	0.2	0.3	-0.5	0.4	0.6	-0.3	0.4	0.5	0.5	-0.5	-0.5	-0.5	-0.5	0.5
Time in familiar zone, hab. session 1	0.3	0.3	0.6	-0.7	0.3	0.5	-0.3	0.6	0.7	0.8	-0.5	-0.5	-0.4	-0.5	0.5
Time in novel zone, hab. session 1	0.3	0.3	0.6	0.6	-0.2	-0.5	0.3	-0.7	-0.6	-0.6	0.5	0.4	0.4	0.4	-0.8
Total zone transitions, hab. session 1	0.8	1.1	1.5	-0.9	1.1	1.2	-0.9	1.0	1.0	0.9	-1.1	-1.1	-1.1	-1.1	1.2
Total locomotion distance, hab. session 1	1.1	1.6	2.5	-1.1	1.6	1.3	-1.6	1.3	1.1	1.0	-1.2	-1.3	-1.3	-1.2	1.2
Locomotion velocity, hab. session 1	1.4	2.0	2.8	-1.2	1.7	1.5	-1.7	1.4	1.2	1.0	-1.4	-1.4	-1.4	-1.3	1.4
Time in familiar zone, hab. session 2	0.9	1.0	2.0	-1.2	0.4	1.0	-0.1	0.9	1.3	1.4	-1.1	-0.9	-1.0	-1.1	0.8
Time in novel zone, hab. session 2	4.5	4.6	5.3	2.3	-1.7	-2.3	1.5	-2.2	-2.3	-2.3	2.2	2.2	2.2	2.2	-2.2
Total zone transitions, hab. session 2	2.1	2.7	4.8	-1.5	2.1	1.7	-2.2	1.2	1.4	1.3	-1.6	-1.7	-1.7	-1.6	1.3
Total locomotion distance, hab. session 2	1.3	1.7	3.9	-1.0	1.7	1.3	-2.0	1.1	1.0	0.9	-1.2	-1.3	-1.3	-1.2	1.1
Locomotion velocity, hab. session 2	1.2	1.6	4.5	-1.0	1.8	1.3	-2.1	1.0	0.9	0.8	-1.1	-1.3	-1.2	-1.1	1.0
Novel to familiar place preference ratio	2.0	2.2	3.7	1.2	-1.5	-1.7	1.9	-1.3	-1.2	-1.1	1.4	1.6	1.6	1.5	-1.5
Novelty place preference	3.2	3.4	5.4	1.6	-1.9	-2.1	2.3	-1.7	-1.5	-1.4	1.8	1.9	1.9	1.8	-2.0
Time in novel zone, NPP test	3.0	3.2	5.5	1.5	-1.9	-2.0	2.3	-1.6	-1.5	-1.3	1.7	1.9	1.8	1.7	-1.9
Total zone transitions, NPP test	1.9	2.7	4.8	-1.5	2.0	1.7	-2.2	1.6	1.4	1.3	-1.6	-1.6	-1.6	-1.5	1.5
Total locomotion distance, NPP test	1.1	1.5	5.0	-0.9	1.8	1.2	-2.2	1.0	0.8	0.6	-1.0	-1.2	-1.1	-1.0	0.9
Locomotion velocity, NPP test	1.0	1.4	5.1	-0.9	1.8	1.1	-2.3	0.9	0.7	0.5	-0.9	-1.1	-1.1	-0.9	0.8
Intraocular pressure	0.5	0.7	1.1	0.4	0.0	-0.8	-0.1	-0.9	-0.9	-0.9	0.9	0.8	0.9	1.0	-1.1
Delta distance traveled before/after self-admin	0.5	0.5	1.4	0.9	-0.8	-0.6	1.2	-0.5	-0.6	-0.5	0.6	0.7	0.6	0.6	-0.5
Delta ambulatory time before/after self-admin	0.8	1.0	2.3	1.5	-1.4	-0.8	1.5	-0.7	-0.9	-0.9	0.8	0.9	0.8	0.7	-0.5
Parametrial fat weight	7.0	16.4	20.5	-4.1	4.1	4.5	-3.8	4.2	4.0	4.0	-4.1	-4.1	-4.0	-4.1	3.6
Pavlov. Cond. lever latency	0.1	0.2	0.4	-0.2	-0.4	0.4	0.6	0.6	0.4	0.5	-0.3	-0.2	-0.2	-0.4	0.4
Pavlov. Cond. magazine entry latency	0.7	0.9	1.9	1.1	-0.7	-1.0	0.4	-1.1	-1.2	-1.4	1.0	0.8	0.8	1.0	-0.7
Pavlov. Cond. change in total contacts	0.9	0.9	1.6	0.8	-0.7	-1.2	0.6	-1.2	-1.0	-1.0	1.0	0.9	1.0	1.0	-1.0
Pavlov. Cond. index score	0.5	0.7	1.4	0.7	-0.3	-1.0	0.0	-1.1	-1.0	-1.2	0.8	0.6	0.7	0.9	-0.6
Pavlov. Cond. latency score	0.4	0.5	1.2	0.7	-0.2	-0.8	-0.1	-1.0	-0.9	-1.1	0.7	0.5	0.6	0.7	-0.5
Pavlov. Cond. lever contacts	0.6	0.7	1.5	0.7	-0.2	-1.0	-0.1	-1.2	-1.0	-1.1	0.9	0.8	0.8	0.9	-0.8
Pavlov. Cond. magazine entry number	0.8	1.0	1.9	-1.1	0.9	1.1	-0.7	1.1	1.2	1.4	-1.0	-0.8	-0.9	-1.0	0.8
Pavlov. Cond. intertrial magazine entries	0.3	0.3	1.1	-0.4	-0.4	0.5	0.4	0.6	0.5	0.5	-0.5	-0.4	-0.5	-0.5	1.1
Pavlov. Cond. lever-magazine prob. diff.	0.6	0.7	1.4	0.8	-0.3	-1.0	0.1	-1.1	-1.0	-1.2	0.8	0.7	0.7	0.9	-0.6
Pavlov. Cond. response bias	0.4	0.5	1.0	0.7	-0.3	-0.8	0.1	-0.9	-0.9	-1.0	0.7	0.5	0.6	0.7	-0.6
Pavlov. Cond. lever latency	1.4	1.9	2.7	-1.4	1.1	1.5	-0.6	1.6	1.6	1.6	-1.4	-1.3	-1.4	-1.5	1.4
Pavlov. Cond. magazine entry latency	3.5	4.3	5.1	2.0	-1.8	-2.3	1.6	-2.3	-2.2	-2.2	2.1	2.1	2.1	2.2	-2.0
Pavlov. Cond. change in total contacts	1.9	3.1	4.6	1.5	-1.2	-2.0	0.6	-2.1	-2.0	-2.0	1.9	1.7	1.8	1.9	-1.7
Pavlov. Cond. index score	3.5	4.7	5.8	2.1	-1.8	-2.3	1.3	-2.4	-2.4	-2.4	2.3	2.1	2.2	2.3	-2.0
Pavlov. Cond. latency score	3.5	4.7	5.9	2.1	-1.7	-2.3	1.4	-2.4	-2.3	-2.4	2.2	2.1	2.2	2.3	-2.1
Pavlov. Cond. lever contacts	1.8	2.4	3.7	1.6	-1.2	-1.6	0.6	-1.8	-1.8	-1.9	1.6	1.5	1.6	1.7	-1.4
Pavlov. Cond. magazine entry number	5.6	6.9	8.6	-2.4	2.3	2.9	-2.1	2.9	2.7	2.7	-2.7	-2.6	-2.7	-2.7	2.7
Pavlov. Cond. intertrial magazine entries	4.3	6.5	7.9	-2.5	2.4	2.8	-2.2	2.7	2.5	2.4	-2.6	-2.7	-2.7	-2.6	2.7
Pavlov. Cond. lever-magazine prob. diff.	3.9	5.2	6.3	2.3	-2.0	-2.5	1.6	-2.5	-2.5	-2.5	2.4	2.3	2.3	2.4	-2.1
Pavlov. Cond. response bias	3.2	4.4	5.8	2.0	-1.7	-2.3	1.2	-2.4	-2.3	-2.4	2.2	2.0	2.1	2.2	-1.9
Time in closed arm before self-admin	4.0	5.1	9.0	-1.9	2.9	2.7	-3.0	2.7	1.9	1.9	-2.0	-2.0	-1.9	-1.9	1.5
Time in closed arm after self-admin	3.3	3.5	4.3	-2.1	2.1	2.0	-1.6	2.0	2.0	2.0	-1.9	-1.9	-1.8	-1.8	1.2
Time in open arm before self-admin	2.1	2.3	3.6	1.5	-1.7	-1.9	1.1	-1.8	-1.7	-1.8	1.5	1.3	1.4	1.5	-0.9
Time in open arm after self-admin	0.9	1.0	2.4	0.4	-1.2	-1.6	0.7	-1.2	-0.8	-0.8	0.9	0.9	0.9	1.0	-1.0
Bone: periosteal estimation	0.2	0.4	0.6	-0.8	0.5	0.7	-0.4	0.6	0.6	0.5	-0.6	-0.7	-0.7	-0.6	0.8
Bone: periosteal perimeter	0.7	1.3	2.3	-1.1	1.3	1.1	-1.5	1.0	0.9	0.8	-1.0	-1.1	-1.1	-1.0	1.3
Bone: post-yield work	0.6	0.8	1.4	-1.0	0.6	0.8	-0.2	1.0	1.1	1.2	-1.0	-0.9	-0.9	-1.0	0.9
Progressive ratio test 1 active lever presses	2.9	3.6	6.9	2.6	-2.4	-1.7	2.1	-1.4	-2.0	-2.1	1.8	1.8	1.7	1.6	-0.8
Progressive ratio test 1 breakpoint	2.6	3.2	6.1	2.5	-2.3	-1.6	2.0	-1.3	-1.9	-2.0	1.7	1.7	1.6	1.5	-0.7
Progressive ratio test 1 inactive lever presses	0.2	0.3	1.7	0.7	-1.1	-0.1	1.3	0.1	-0.1	-0.1	0.1	0.2	0.1	-0.0	0.4
Progressive ratio test 2 active lever presses	2.1	2.5	7.3	2.7	-2.2	-1.0	1.9	-0.7	-1.7	-1.7	1.4	1.4	1.2	1.1	-0.1
Progressive ratio test 2 breakpoint	2.3	2.6	7.3	2.7	-2.3	-1.1	1.9	-0.8	-1.7	-1.7	1.4	1.5	1.3	1.1	-0.2
Progressive ratio test 2 inactive lever presses	0.1	0.2	0.8	0.5	-0.8	-0.2	0.9	0.0	-0.1	-0.0	0.2	0.3	0.3	0.1	0.0
Incentive Sensitization - Responses	0.6	0.8	3.7	1.9	-1.1	-0.2	0.9	-0.1	-1.0	-1.0	0.7	0.8	0.6	0.5	0.3
Incentive Sensitization - Breakpoint	0.8	1.0	4.3	2.1	-1.2	-0.2	1.0	-0.2	-1.1	-1.1	0.8	0.9	0.7	0.5	0.2
Sum of active levers in priming session hrs 5-6	0.3	0.3	0.7	0.1	-0.5	-0.6	0.4	-0.8	-0.3	-0.3	0.5	0.6	0.6	0.6	-0.7
Progressive ratio	0.4	0.6	1.4	-1.1	0.9	-0.9	-0.9	-1.1	-0.0	-0.0	0.2	0.1	0.3	0.5	-1.2
Food seeking constrained by brief footshock	1.7	2.1	3.9	1.1	-0.8	-1.8	0.4	-2.0	-1.6	-1.6	1.5	1.4	1.5	1.6	-1.5
Seeking ratio, punishment vs. effort	0.6	0.8	2.3	1.5	-1.4	-0.6	1.1	-0.4	-0.9	-1.0	0.8	0.9	0.8	0.7	-0.0
Retroperitoneal fat weight	6.3	26.7	31.4	-5.6	4.3	5.2	-3.7	5.4	5.5	5.5	-5.4	-5.3	-5.3	-5.3	5.1
Reaction time number correct	0.8	1.6	3.2	1.8	-1.2	-0.6	1.0	-0.6	-1.5	-1.5	1.4	1.4	1.3	1.3	-0.9
Reaction time mean minus median	0.7	1.7	3.7	0.5	-0.4	-1.6	0.9	-1.9	-1.2	-1.1	1.3	1.2	1.4	1.4	-1.9
Reaction time mean minus median AUC	0.6	1.4	3.7	0.4	-0.0	-1.4	0.5	-1.7	-1.1	-1.1	1.2	1.1	1.2	1.4	-1.9
Reaction time num false alarms	0.1	0.1	0.3	0.4	-0.6	-0.2	0.4	-0.2	-0.2	-0.2	0.3	0.4	0.4	0.3	0.1
Reaction time num false alarms AUC	0.1	0.1	0.5	0.2	-0.2	0.4	0.0	0.3	0.1	0.1	-0.1	-0.1	-0.1	-0.2	0.7
Reaction time trials correct on left	0.8	1.6	3.2	1.8	-1.2	-0.6	1.0	-0.6	-1.5	-1.5	1.4	1.4	1.3	1.3	-0.9
Reaction time trials on left	0.9	1.6	3.4	1.8	-1.2	-0.7	1.0	-0.7	-1.5	-1.5	1.4	1.4	1.3	1.3	-0.9
Reaction time mean	0.4	0.6	2.0	-1.0	1.0	-0.8	-0.7	-0.8	0.0	0.1	0.3	0.3	0.5	0.6	-1.4
Reaction time mean AUC	0.4	0.7	2.8	-0.7	0.9	-0.9	-0.5	-1.0	-0.2	-0.1	0.6	0.6	0.8	0.9	-1.7
Median of all reaction times	0.4	0.5	1.8	-1.3	1.3	-0.4	-1.1	-0.3	0.4	0.5	-0.0	-0.0	0.2	0.2	-0.9
Reaction time omissions	0.0	0.1	0.3	0.1	0.0	0.2	0.2	0.1	-0.1	-0.2	-0.2	-0.3	-0.3	-0.3	0.6
Reaction time false alarm rate	0.4	0.5	1.2	-0.7	0.3	0.7	-0.5	0.6	0.8	0.8	-0.8	-0.7	-0.7	-0.8	1.1
Reaction time premature initiation rate	1.4	2.0	3.1	1.1	-1.0	-1.8	1.0	-1.8	-1.5	-1.4	1.4	1.3	1.4	1.5	-1.6
Reaction time premature initiations	2.3	4.1	4.9	2.1	-1.6	-2.1	1.4	-2.1	-2.2	-2.2	2.1	2.1	2.1	2.1	-2.1
Std. dev. reaction times	0.3	0.6	2.5	-0.3	0.6	-1.0	-0.3	-1.1	-0.5	-0.3	0.7	0.6	0.8	0.8	-1.6
Reaction time trials completed	0.9	1.6	3.4	1.8	-1.2	-0.7	1.0	-0.7	-1.5	-1.5	1.4	1.4	1.3	1.3	-0.9
Reaction time trials AUC	0.9	1.7	3.4	1.8	-1.2	-0.7	1.0	-0.7	-1.5	-1.6	1.4	1.4	1.4	1.3	-1.0
Run reversals in cocaine runway, females	2.0	2.0	3.6	-1.0	1.2	1.5	-1.8	1.7	1.2	1.1	-1.3	-1.4	-1.4	-1.4	1.9
Run reversals in cocaine runway, males	0.5	0.6	1.8	-0.0	0.5	0.7	-0.9	0.8	0.3	0.2	-0.7	-0.8	-0.8	-0.8	1.3
Latency to leave start box in cocaine runway	0.2	0.2	0.8	0.2	0.3	-0.2	-0.1	-0.1	-0.3	-0.2	0.5	0.6	0.6	0.5	-0.9
Latency to leave start box in cocaine runway, F	1.0	1.1	2.1	1.5	-1.3	-1.0	1.4	-0.7	-0.9	-0.7	1.0	1.2	1.1	0.9	-1.1
Latency to leave start box in cocaine runway, M	1.8	1.7	6.3	-1.9	2.5	1.0	-2.3	0.6	1.0	1.0	-0.8	-0.8	-0.6	-0.5	-0.2
Std. dev. time between licks in bursts	1.7	2.3	3.0	-1.7	1.5	1.5	-1.7	1.5	1.5	1.3	-1.5	-1.6	-1.6	-1.5	1.4
Total sessions with >9 infusions	1.5	1.9	4.3	2.1	-2.0	-1.1	1.7	-0.8	-1.4	-1.5	1.2	1.2	1.1	1.0	-0.2
Short access day 1 total inactive lever presses	0.0	0.0	0.1	0.0	-0.1	0.2	0.3	0.1	0.2	0.3	-0.1	-0.0	-0.1	-0.2	-0.1
Short access day 10 total inactive lever presses	0.1	0.2	0.4	-0.5	0.1	0.6	0.2	0.4	0.6	0.6	-0.5	-0.5	-0.5	-0.5	0.5
Short access day 1 total infusions	0.4	0.6	2.4	1.5	-1.3	-0.2	1.1	-0.0	-0.7	-0.7	0.4	0.5	0.3	0.2	0.5
Short access day 10 total infusions	0.3	0.4	1.8	1.4	-1.0	0.0	1.0	0.1	-0.5	-0.5	0.4	0.5	0.3	0.2	0.2
Short access total infusions	1.8	2.2	5.7	2.4	-2.1	-1.1	2.0	-0.9	-1.5	-1.5	1.3	1.4	1.2	1.0	-0.5
Short access day 1 locomotion	0.2	0.3	1.3	1.2	-0.7	-0.3	0.3	-0.2	-0.7	-0.8	0.4	0.3	0.2	0.2	0.2
Short access day 10 total locomotion	1.6	3.0	4.6	-1.8	0.9	1.8	-0.4	1.9	2.1	2.2	-1.8	-1.6	-1.7	-1.8	1.8
Short access total locomotion	0.4	0.5	0.9	-0.5	0.2	0.8	0.2	0.9	0.9	0.9	-0.7	-0.6	-0.7	-0.8	0.8
One hour access (0.3 mA shock)	1.0	1.1	3.8	2.0	-1.3	-0.5	1.2	-0.5	-1.2	-1.2	0.9	1.0	0.9	0.7	-0.2
Compulsive drug intake	0.1	0.2	0.6	-0.6	0.7	-0.1	-0.8	-0.1	0.2	0.2	-0.3	-0.4	-0.3	-0.2	-0.1
One hour access (shock baseline)	0.8	1.2	4.6	2.1	-1.4	-0.2	1.3	-0.2	-1.1	-1.1	0.9	1.1	0.9	0.7	-0.1
Social response proportion	0.8	1.0	3.2	1.3	-1.8	-0.6	1.7	-0.6	-0.7	-0.8	0.7	0.7	0.6	0.5	-0.2
Social responses	0.1	0.2	0.9	0.4	-1.0	-0.0	0.8	-0.2	-0.1	-0.2	0.0	0.0	-0.0	-0.1	0.2
Social time	0.1	0.1	0.6	0.4	-0.8	0.1	0.6	0.3	-0.1	-0.1	0.1	0.1	0.0	-0.0	0.4
Soleus weight	0.1	0.4	1.0	-1.0	0.5	0.5	-0.3	0.4	0.7	0.7	-0.7	-0.7	-0.7	-0.6	0.4
Bone: stiffness	3.4	5.5	7.1	2.1	-2.1	-2.6	2.1	-2.7	-2.4	-2.5	2.4	2.3	2.4	2.4	-2.1
Tibialis anterior weight	0.3	0.9	1.9	0.9	-0.1	-0.9	-0.0	-1.1	-1.3	-1.4	1.0	0.8	0.9	1.1	-0.9
Time to tail flick, vehicle, before self-admin	0.5	0.5	1.5	1.2	-0.9	-0.7	0.8	-0.4	-0.8	-0.8	0.6	0.7	0.6	0.5	-0.4
Time to tail flick, vehicle, after self-admin	1.2	1.7	4.6	-0.4	0.9	2.2	-0.5	1.9	1.1	1.1	-1.2	-1.1	-1.3	-1.4	1.3
Time to tail flick, test, before self-admin	3.4	3.5	5.8	-1.3	1.9	2.4	-2.0	2.1	1.6	1.6	-1.9	-1.9	-1.9	-1.9	1.9
Time to tail flick, test, after self-admin	0.2	0.3	0.8	0.2	-0.6	0.6	0.9	0.5	0.2	0.2	-0.4	-0.4	-0.4	-0.5	0.7
Delta time to tail flick, vehicle, before/after SA	1.4	1.3	4.5	-0.5	0.9	2.1	-0.6	1.5	0.9	0.9	-1.1	-1.0	-1.1	-1.2	1.1
Delta time to tail flick, test, before/after SA	1.6	1.6	3.4	1.2	-1.8	-1.5	1.8	-1.3	-1.1	-1.2	1.1	1.1	1.0	1.1	-0.7
Tibia length	0.1	0.2	1.1	0.2	0.7	-0.1	-1.0	-0.3	-0.4	-0.4	0.2	0.2	0.2	0.3	-0.6
Ambulatory time before self-admin	0.9	1.4	5.6	-2.4	1.2	0.6	-1.1	0.7	1.3	1.3	-1.0	-1.1	-0.9	-0.7	0.7
Ambulatory time after self-admin	0.3	0.3	1.1	-1.0	-0.1	-0.2	0.4	0.3	0.7	0.6	-0.5	-0.6	-0.5	-0.4	0.6
Bone: tissue strength	0.5	0.5	2.7	0.4	-1.3	-0.6	1.6	-0.2	-0.0	0.2	0.3	0.5	0.4	0.2	-0.5
Total heroin consumption	0.9	1.0	1.5	1.2	-0.7	-0.7	1.0	-0.8	-1.0	-0.9	1.1	1.2	1.1	1.1	-1.2
Bone: trabecular number	0.4	0.6	1.2	-1.0	1.1	0.5	-1.1	0.5	0.8	0.8	-0.7	-0.7	-0.6	-0.6	0.5
Bone: trabecular spacing	0.1	0.1	0.5	0.0	0.0	0.7	0.0	0.6	0.1	0.1	-0.2	-0.3	-0.3	-0.3	0.5
Bone: trabecular thickness	0.5	0.7	1.4	0.5	0.1	-1.1	-0.3	-1.2	-0.8	-0.8	0.8	0.8	0.8	0.9	-1.1
Bone: trabecular tissue density	0.7	1.0	1.6	1.0	-0.9	-1.1	1.0	-1.0	-0.9	-0.9	1.0	1.0	1.0	1.0	-1.3
Water consumed over 24 hours	0.2	0.3	0.6	-0.4	-0.1	0.4	0.2	0.4	0.4	0.3	-0.6	-0.7	-0.6	-0.6	0.8
Number of responses in last shaping day	0.8	0.8	1.9	0.1	-0.4	-1.4	0.2	-1.1	-0.8	-0.8	1.0	0.9	1.1	1.2	-1.1