Hub : Genes

LOC134481741

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression LOC134481741 0.03 0.03 3.1e-05 0.03 0.04 0.04 0.04 6.5e-05 1.9e-06 9.3e-07 2.0e-06
2 Brain gene expression LOC134481741 0.09 0.04 2.7e-10 0.09 0.1 0.09 0.1 5.2e-09 3.9e-09 7.9e-09 3.1e-09
3 PL gene expression LOC134481741 0.03 0.02 1.5e-03 0 0 -0 -0 2.4e-01 9.1e-02 5.5e-01 4.6e-01
4 Liver gene expression LOC134481741 0.02 0.02 8.0e-03 0.02 0.01 0.01 0.01 6.1e-03 3.9e-02 1.0e-02 2.4e-02
5 Brain mRNA stability LOC134481741 0.03 0.02 4.8e-03 0.02 0.01 0 0.01 1.2e-02 1.5e-02 1.6e-01 4.5e-02
6 Adipose mRNA stability LOC134481741 0.03 0.02 1.1e-04 0.03 0.03 0.03 0.03 2.0e-04 1.5e-04 1.7e-04 1.2e-04
7 Adipose gene expression LOC134481741 0.1 0.04 2.2e-16 0.15 0.15 0.13 0.15 1.4e-16 6.2e-16 1.7e-14 5.2e-16
8 BLA gene expression LOC134481741 0.06 0.05 1.7e-03 0.01 0.01 -0 0 6.3e-02 7.3e-02 6.1e-01 2.3e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density0.20.41.2-1.11.10.9-0.3-0.30.2-0.2-0.3
Area under the delay curve0.50.71.0-1.00.90.9-0.7-0.90.7-0.8-0.8
BMI with tail0.10.41.10.1-0.4-0.30.61.1-0.70.80.8
BMI without tail0.00.21.0-0.1-0.4-0.00.51.0-0.40.30.4
Body weight0.10.21.1-0.1-0.1-0.20.31.0-0.30.50.5
Weight adjusted by age0.20.61.60.8-0.8-0.61.20.5-0.60.40.7
Bone surface0.00.10.3-0.60.40.10.20.3-0.20.20.1
Bone volume0.00.10.2-0.30.30.30.30.0-0.40.40.2
Breakpoint value in progressive ratio session1.32.33.1-1.61.41.7-1.6-0.91.4-1.7-1.8
Number of licking bursts0.10.30.50.1-0.3-0.50.70.6-0.50.50.5
Context. condit. distance diff. score3.44.14.82.0-2.1-1.62.22.0-2.22.02.1
Locomotion velocity, session 10.40.50.70.8-0.8-0.70.70.7-0.70.50.6
Locomotion distance, session 10.50.61.00.9-1.0-0.90.90.7-0.70.40.5
Locomotion velocity, session 20.20.30.6-0.20.30.6-0.5-0.30.7-0.8-0.6
Locomotion distance, session 21.52.13.1-1.31.31.4-1.4-1.31.6-1.8-1.6
Locomotion velocity, session 30.91.01.61.1-0.8-0.91.20.4-1.11.01.2
Locomotion distance, session 31.61.82.21.4-1.5-1.31.51.3-1.41.11.4
Stereotopy head waving bouts, day 31.41.73.6-0.61.21.7-1.3-1.91.3-1.1-1.0
Stereotopy head waving duration, day 30.91.14.62.2-1.5-0.60.50.2-0.60.70.7
Locomotion velocity, session 73.13.54.42.1-2.0-1.41.62.0-1.81.92.0
Locomotion distance, session 74.35.59.93.1-2.9-2.61.91.7-2.12.12.1
Stereotopy head waving bouts, day 70.80.91.9-0.81.01.0-1.0-1.40.8-0.8-0.7
Stereotopy head waving duration, day 74.35.37.1-2.62.72.5-2.0-2.32.1-2.1-1.8
Locomotion velocity, session 80.30.40.6-0.70.80.7-0.5-0.50.6-0.7-0.6
Locomotion distance, session 81.31.92.61.5-1.6-1.21.61.4-1.41.11.2
Degree of sensitization distance1.41.53.11.8-1.5-1.20.80.7-1.01.31.0
Degree of sensitization stereotypy2.12.44.1-2.01.91.5-1.4-1.41.3-1.3-1.2
Conditioned locomotion0.40.40.9-0.30.31.0-0.7-0.60.7-0.8-0.6
Cocaine response after cond. corrected0.30.50.7-0.60.50.8-0.8-0.00.8-0.8-0.7
Cocaine response after cond. not corrected0.10.10.3-0.1-0.20.1-0.20.50.4-0.4-0.4
Cocaine response before conditioning0.30.40.70.6-0.7-0.80.80.3-0.60.50.5
Saline control response0.20.20.50.3-0.3-0.70.60.2-0.60.60.5
Bone: connectivity density2.64.16.8-2.62.42.0-2.0-1.11.9-1.8-2.1
Bone: cortical apparent density0.60.91.9-1.41.21.2-0.7-0.80.7-0.5-0.6
Bone: cortical area1.01.62.50.9-0.9-1.11.50.6-1.61.61.6
Bone: cortical porosity1.61.82.9-1.31.41.4-1.2-1.71.2-1.2-1.2
Bone: cortical porosity2.02.23.7-1.51.71.6-1.2-1.91.2-1.2-1.2
Bone: cortical thickness1.22.03.21.1-0.9-1.41.60.6-1.61.81.8
Bone: cortical thickness0.10.10.80.00.30.4-0.2-0.90.2-0.1-0.1
Bone: cortical tissue density0.50.91.9-1.41.21.2-0.7-0.80.7-0.5-0.6
Condit. Reinf. active minus inactive responses0.20.20.50.00.10.6-0.7-0.20.5-0.5-0.3
Condit. Reinf. active-inactive response ratio0.10.10.60.3-0.30.4-0.10.8-0.20.20.2
Condit. Reinf. active responses0.91.21.6-0.40.81.2-1.2-1.31.2-1.2-1.0
Condit. Reinf. inactive responses0.81.02.7-0.50.90.7-0.8-1.61.0-1.0-0.9
Incentive salience index mean0.81.01.5-0.90.91.2-1.1-0.81.1-1.2-1.0
Condit. Reinf. lever presses1.62.33.0-1.71.61.3-1.3-1.61.5-1.7-1.4
Condit. Reinf. active minus inactive responses0.20.30.60.8-0.7-0.60.30.3-0.40.50.5
Condit. Reinf. active-inactive response ratio0.00.10.30.2-0.4-0.00.00.6-0.10.00.1
Condit. Reinf. active responses0.81.11.51.2-1.2-1.21.10.6-1.11.00.9
Condit. Reinf. inactive responses1.52.22.91.6-1.5-1.71.70.8-1.61.51.4
Condit. Reinf. lever presses0.20.30.5-0.70.70.2-0.6-0.70.5-0.5-0.6
Condit. Reinf. lever reinforcers received0.40.50.80.9-0.8-0.90.70.3-0.70.60.6
Conditioned reinforcement - actives0.31.22.01.4-1.0-1.40.90.3-1.01.21.2
Conditioned reinforcement - inactives0.72.03.4-1.10.81.3-1.7-0.81.6-1.9-1.6
Conditioned locomotion0.40.61.10.4-0.8-0.91.00.7-1.00.50.7
Patch foraging indifference point 0 sec1.64.67.12.4-2.1-2.72.21.1-2.22.22.0
Patch foraging indifference point AUC1.22.85.11.5-2.1-1.51.62.3-1.41.31.3
Delay disc. indifference point, 0s delay0.60.62.1-0.60.60.6-0.4-1.50.5-0.9-0.9
Delay disc. indifference point, 16s delay0.81.11.7-1.31.21.3-0.8-1.01.0-0.9-0.9
Delay disc. indifference point, 2s delay0.10.10.2-0.30.30.4-0.3-0.10.0-0.2-0.2
Delay disc. indifference point, 24s delay0.40.71.6-1.31.01.0-0.2-0.70.7-0.7-0.7
Delay disc. indifference point, 4s delay0.50.50.7-0.60.60.8-0.7-0.80.4-0.8-0.8
Delay disc. indifference point, 8s delay0.10.20.3-0.50.40.5-0.4-0.50.4-0.5-0.5
Indifference point function ln k0.61.93.3-1.11.41.3-1.5-1.81.3-1.3-1.3
Indifference point function log k0.61.93.3-1.11.41.3-1.5-1.81.3-1.3-1.3
Patch foraging total patch changes 0 sec2.36.89.92.9-2.5-3.12.61.5-2.62.72.5
Patch foraging total patch changes 12 sec1.72.33.31.5-1.6-1.81.41.6-1.41.41.4
Patch foraging total patch changes 18 sec3.07.08.22.8-2.9-2.82.72.4-2.52.52.4
Patch foraging total patch changes 24 sec1.55.06.42.3-2.3-2.52.41.8-2.22.12.2
Patch foraging total patch changes 6 sec3.45.87.92.3-2.8-2.52.62.6-2.31.92.0
Patch foraging time to switch 0 sec0.41.52.9-1.61.71.0-1.0-1.11.0-1.0-1.0
Patch foraging water rate 0 sec0.10.41.51.2-1.0-0.60.30.3-0.30.40.4
Patch foraging water rate 12 sec0.00.20.70.8-0.80.0-0.10.20.1-0.1-0.0
Patch foraging water rate 18 sec0.92.13.1-1.31.21.8-1.6-1.11.4-1.6-1.5
Patch foraging water rate 24 sec0.30.41.0-0.40.51.0-0.7-0.50.6-0.8-0.5
Patch foraging water rate 6 sec0.10.20.50.3-0.10.7-0.6-0.30.4-0.4-0.5
Seeking ratio, delayed vs. immediate footshock1.62.33.1-1.51.41.3-1.6-1.11.6-1.8-1.8
Distance traveled before self-admin0.20.41.10.2-0.5-0.40.51.0-0.80.50.5
Distance traveled after self-admin0.10.20.40.5-0.3-0.50.4-0.2-0.50.60.6
Extensor digitorum longus weight1.24.79.1-3.02.72.0-1.8-1.41.9-2.0-1.9
Bone: elastic displacement0.00.00.10.1-0.20.20.2-0.3-0.2-0.00.1
Bone: elastic work0.10.10.20.2-0.3-0.20.4-0.5-0.50.20.3
Bone: endosteal estimation0.20.61.00.2-0.6-0.51.00.9-1.00.90.8
Bone: endosteal perimeter0.10.30.40.5-0.6-0.50.50.6-0.60.60.4
Epididymis fat weight0.41.83.11.0-1.2-1.51.11.8-1.31.41.4
Delta time in closed arm before/after self-admin2.72.63.31.8-1.8-1.51.61.2-1.71.61.7
Delta time in open arm before/after self-admin0.40.51.5-0.40.90.1-0.9-1.20.7-0.2-0.4
Diff in mean of infusions in LGA sessions0.50.91.4-0.80.71.2-0.9-0.41.0-1.0-1.2
Delay discount exponential model param0.30.30.60.8-0.7-0.60.40.6-0.40.60.6
Extinction: sum of active levers before priming0.00.00.20.4-0.3-0.3-0.1-0.0-0.1-0.1-0.1
Active lever presses in extinction session 60.00.00.1-0.20.3-0.0-0.3-0.3-0.20.10.1
Bone: final force0.10.20.6-0.70.70.7-0.1-0.50.1-0.2-0.1
Bone: final moment0.30.50.9-0.91.00.9-0.4-0.80.4-0.4-0.4
Food consumed during 24 hour testing period0.00.00.00.2-0.0-0.0-0.00.1-0.00.0-0.2
Glucose0.00.10.50.1-0.30.00.00.7-0.10.10.1
Heart weight0.10.20.6-0.40.00.8-0.10.50.5-0.4-0.3
Delay discount hyperbolic model param0.30.40.60.8-0.7-0.70.50.6-0.40.60.6
Intermittent access intake day 1-15 change0.53.05.4-1.42.01.3-2.1-2.31.8-1.2-1.3
Intermittent access intake escalation0.63.25.4-1.52.11.4-2.1-2.31.8-1.4-1.4
Intermittent access intake escalation 22.64.36.5-1.72.31.8-2.5-2.62.2-1.7-1.7
Intermitt. access day 1 inactive lever presses0.33.45.22.3-2.2-1.71.91.5-1.61.71.7
Intermitt. access day 15 inactive lever presses0.42.22.9-1.71.31.7-1.4-1.01.4-1.6-1.5
Intermitt. access escalation Index0.00.00.20.0-0.30.00.10.4-0.3-0.0-0.1
Intermittent access day 1 total infusions0.00.10.20.4-0.3-0.1-0.1-0.30.3-0.3-0.3
Intermittent access day 15 total infusions1.02.54.1-0.91.41.3-2.0-2.01.7-1.5-1.6
Intermittent access terminal intake (last 3 days)1.93.35.3-1.01.61.5-2.3-2.32.1-1.7-1.8
Intermittent access total infusions0.40.51.2-0.20.50.4-1.1-1.00.9-0.7-0.7
Intermittent access day 1 locomotion0.71.22.01.4-1.2-1.11.20.8-1.11.00.9
Intermittent access day 15 total locomotion0.10.50.9-0.50.70.3-0.9-0.80.9-0.7-0.7
Intermittent access total locomotion0.10.10.40.4-0.6-0.40.30.5-0.30.10.2
Intermittent access standard deviation0.10.31.4-0.10.7-0.3-0.4-1.20.30.10.2
Left kidney weight0.10.71.4-0.2-0.2-0.51.11.2-1.01.00.9
Right kidney weight0.42.73.71.2-1.5-1.91.71.6-1.61.71.7
Cocaine induced anxiety0.30.81.1-1.00.61.1-0.4-1.01.0-1.0-1.0
Post-drug Anxiety0.81.02.9-1.71.31.0-0.6-0.30.7-0.7-0.8
Baseline Anxiety0.10.21.2-0.1-0.1-0.30.21.1-0.50.30.3
Tail length0.10.81.90.6-0.9-1.00.91.4-0.80.70.7
Length with tail0.00.20.60.2-0.3-0.60.30.8-0.20.40.3
Length without tail0.10.71.20.7-0.6-1.10.70.8-0.71.00.8
Times rat made contact with spout0.10.10.20.2-0.3-0.30.50.2-0.30.20.1
Lifetime Intake0.20.20.6-0.00.40.2-0.8-0.80.6-0.4-0.3
Liver weight, left1.11.92.81.4-1.2-1.31.41.0-1.51.71.5
Liver weight, right0.10.20.6-0.10.20.8-0.4-0.30.5-0.5-0.5
Locomotor activity5.38.311.23.3-3.3-3.12.62.7-2.62.62.6
Locomotor testing distance4.09.913.63.6-3.4-3.72.82.7-2.83.02.9
Locomotor testing rearing1.34.66.42.3-2.2-2.51.82.1-2.12.12.1
Locomotion in novel chamber1.82.44.9-1.01.41.0-1.8-2.21.4-1.4-1.8
Locomotion in novel chamber post-restriction0.10.40.90.1-0.6-0.40.81.0-0.70.50.7
Fecal boli incidents, locomotor time 12.05.26.22.2-2.4-2.52.32.2-2.32.12.1
Change in fecal boli incidents, locomotor task1.31.42.6-1.11.21.3-1.6-0.71.1-1.0-1.0
Time >=10cm from walls, locomotor time 10.00.10.1-0.00.1-0.30.4-0.3-0.20.20.2
Bouts of movement, locomotor time 10.00.10.30.10.30.20.0-0.5-0.10.20.2
Total resting periods, locomotor time 10.10.10.30.10.30.10.2-0.5-0.30.50.5
Rest time, locomotor task time 10.81.42.31.4-1.4-0.90.81.5-1.01.01.1
Distance moved, locomotor task time 10.72.04.6-1.21.41.4-0.9-2.11.5-1.3-1.3
Vertical activity count, locomotor time 10.64.55.1-2.02.12.1-1.8-2.22.3-2.2-2.2
Time >=10cm from walls, locomotor time 20.72.12.6-1.41.41.6-1.4-0.91.6-1.6-1.6
Bouts of movement, locomotor time 20.10.20.50.7-0.6-0.30.20.1-0.50.50.5
Total resting periods, locomotor time 20.20.71.31.1-1.1-0.60.60.5-0.90.80.8
Rest time, locomotor task time 23.35.58.12.8-2.8-2.11.92.6-2.12.12.1
Distance moved, locomotor task time 26.38.412.5-3.03.32.5-2.4-3.52.9-2.7-2.7
Vertical activity count, locomotor time 24.310.111.5-3.43.22.9-2.8-3.13.3-3.4-3.4
Light reinforcement 10.10.51.80.1-0.7-0.40.91.3-0.60.50.5
Light reinforcement 20.40.91.21.0-1.1-1.01.00.8-0.90.90.9
Bone: marrow area0.20.50.90.2-0.5-0.40.90.8-1.00.80.7
Bone: maximum diameter0.61.21.70.9-1.0-1.11.20.6-1.31.31.2
Bone: maximum force0.20.40.70.2-0.1-0.50.8-0.0-0.80.80.9
Bone: maximum moment0.10.20.3-0.00.1-0.20.5-0.3-0.50.50.5
Mean time between licks in bursts0.42.44.01.8-2.0-1.11.71.4-1.51.31.4
Mean num. licks in bursts0.00.10.20.20.00.3-0.4-0.40.3-0.3-0.5
Cd content in liver1.11.21.81.2-1.2-1.00.91.4-1.01.01.0
Co content in liver1.21.51.7-1.21.21.2-1.2-0.91.3-1.3-1.3
Cu content in liver0.00.00.10.2-0.1-0.10.00.00.2-0.1-0.1
Fe content in liver0.20.20.4-0.40.60.3-0.4-0.60.4-0.4-0.4
K content in liver3.73.74.51.4-1.6-1.72.12.1-2.12.12.1
Mg content in liver3.23.53.82.0-1.9-1.71.91.9-1.81.91.9
Mn content in liver7.88.810.3-3.13.23.0-3.1-2.43.1-2.8-2.8
Na content in liver0.00.00.1-0.20.1-0.10.10.30.0-0.0-0.1
Rb content in liver0.10.10.3-0.50.30.3-0.10.60.1-0.1-0.1
Se content in liver0.91.12.0-0.91.21.1-1.0-1.41.0-0.9-0.9
Sr content in liver0.10.10.4-0.70.50.2-0.00.10.0-0.0-0.0
Zn content in liver1.51.73.01.7-1.7-0.81.21.6-1.01.01.0
Bone: minimum diameter1.12.13.01.3-1.3-1.31.71.0-1.71.71.6
Time in familiar zone, hab. session 10.10.10.2-0.3-0.00.0-0.30.30.4-0.5-0.5
Time in novel zone, hab. session 10.10.10.30.4-0.1-0.10.4-0.1-0.30.50.5
Total zone transitions, hab. session 10.50.71.4-0.40.30.9-0.6-0.71.0-1.2-1.1
Total locomotion distance, hab. session 18.211.727.25.2-4.7-2.92.92.5-2.72.72.6
Locomotion velocity, hab. session 18.411.926.95.2-4.7-3.03.02.4-2.82.72.7
Time in familiar zone, hab. session 20.20.31.8-0.1-0.40.10.11.3-0.1-0.1-0.1
Time in novel zone, hab. session 20.60.73.8-0.20.80.3-0.7-1.90.4-0.2-0.4
Total zone transitions, hab. session 20.00.00.2-0.2-0.00.00.4-0.1-0.0-0.2-0.1
Total locomotion distance, hab. session 28.611.320.54.5-4.3-3.03.32.7-2.92.82.9
Locomotion velocity, hab. session 28.211.019.94.5-4.2-3.03.32.6-2.92.72.9
Novel to familiar place preference ratio0.20.30.6-0.00.40.5-0.6-0.80.6-0.4-0.4
Novelty place preference0.40.60.9-0.40.70.7-0.9-0.90.8-0.7-0.7
Time in novel zone, NPP test0.91.11.6-0.71.11.0-1.2-1.31.1-1.0-1.0
Total zone transitions, NPP test0.81.22.61.0-1.2-1.01.61.1-1.00.80.9
Total locomotion distance, NPP test11.716.329.35.4-5.0-3.94.02.8-3.53.53.6
Locomotion velocity, NPP test12.818.332.05.7-5.2-4.24.23.0-3.83.83.8
Intraocular pressure1.11.83.5-0.41.01.4-1.8-1.91.3-1.2-1.1
Delta distance traveled before/after self-admin0.50.50.90.9-0.4-0.80.6-0.4-0.51.00.9
Delta ambulatory time before/after self-admin0.10.20.50.7-0.4-0.50.3-0.4-0.30.50.5
Parametrial fat weight0.82.02.91.7-1.5-1.31.41.2-1.31.31.5
Pavlov. Cond. lever latency0.70.81.40.9-0.9-1.10.61.2-0.71.00.6
Pavlov. Cond. magazine entry latency0.20.31.60.10.30.2-0.3-1.30.3-0.4-0.2
Pavlov. Cond. change in total contacts1.41.53.5-0.81.21.1-1.2-1.91.1-1.1-1.0
Pavlov. Cond. index score0.50.61.9-0.50.70.8-0.6-1.40.7-0.8-0.6
Pavlov. Cond. latency score0.20.21.0-0.20.40.5-0.2-1.00.2-0.5-0.2
Pavlov. Cond. lever contacts0.70.91.7-0.80.91.2-0.6-1.30.7-1.1-0.7
Pavlov. Cond. magazine entry number0.91.13.20.4-0.7-0.91.01.8-1.01.11.0
Pavlov. Cond. intertrial magazine entries2.53.03.6-1.51.51.8-1.9-1.51.9-1.8-1.8
Pavlov. Cond. lever-magazine prob. diff.0.91.12.7-0.71.01.0-0.8-1.70.9-1.0-0.9
Pavlov. Cond. response bias1.01.33.4-0.71.01.1-0.9-1.81.0-1.2-1.0
Pavlov. Cond. lever latency0.30.50.60.6-0.7-0.30.70.8-0.70.70.8
Pavlov. Cond. magazine entry latency0.30.51.1-0.80.90.3-0.7-1.00.5-0.5-0.6
Pavlov. Cond. change in total contacts0.00.00.2-0.10.2-0.4-0.2-0.1-0.10.1-0.0
Pavlov. Cond. index score0.30.40.7-0.60.80.1-0.7-0.90.6-0.6-0.6
Pavlov. Cond. latency score0.20.40.6-0.60.70.1-0.7-0.80.6-0.6-0.7
Pavlov. Cond. lever contacts0.30.50.7-0.70.80.4-0.7-0.70.7-0.7-0.7
Pavlov. Cond. magazine entry number0.40.51.00.9-1.0-0.30.60.9-0.60.50.6
Pavlov. Cond. intertrial magazine entries1.43.14.61.9-2.1-1.31.92.0-1.71.51.5
Pavlov. Cond. lever-magazine prob. diff.0.20.20.5-0.50.7-0.1-0.5-0.70.4-0.4-0.4
Pavlov. Cond. response bias0.50.71.3-0.81.00.5-0.9-1.10.8-0.8-0.8
Time in closed arm before self-admin0.20.30.9-0.81.0-0.1-0.5-0.60.4-0.1-0.2
Time in closed arm after self-admin0.70.71.10.8-0.8-1.00.90.5-0.90.90.9
Time in open arm before self-admin3.84.67.42.6-2.7-1.62.12.2-2.11.71.8
Time in open arm after self-admin0.60.71.51.2-0.9-1.00.40.3-0.80.90.8
Bone: periosteal estimation0.71.62.60.8-0.9-1.01.50.9-1.61.51.4
Bone: periosteal perimeter0.51.01.31.0-1.0-1.10.90.8-1.11.11.0
Bone: post-yield work0.00.00.00.1-0.0-0.0-0.00.00.00.10.0
Progressive ratio test 1 active lever presses0.10.30.70.8-0.7-0.30.30.3-0.30.40.6
Progressive ratio test 1 breakpoint0.30.51.11.0-0.8-0.50.50.4-0.50.60.8
Progressive ratio test 1 inactive lever presses0.00.10.3-0.1-0.20.60.00.50.1-0.1-0.1
Progressive ratio test 2 active lever presses0.60.81.6-0.20.60.4-1.2-1.31.1-0.9-0.8
Progressive ratio test 2 breakpoint0.60.71.4-0.10.60.4-1.2-1.21.1-0.9-0.8
Progressive ratio test 2 inactive lever presses0.41.42.7-0.40.80.8-1.5-1.61.4-1.3-1.1
Incentive Sensitization - Responses1.23.44.2-1.71.71.7-2.0-1.82.1-2.0-1.9
Incentive Sensitization - Breakpoint1.53.34.1-1.61.71.6-2.0-1.82.0-2.0-1.8
Sum of active levers in priming session hrs 5-61.31.32.1-1.31.50.9-1.4-0.91.0-0.9-1.0
Progressive ratio2.16.28.02.1-2.3-2.82.42.7-2.52.52.5
Food seeking constrained by brief footshock3.74.65.92.0-2.2-2.22.12.4-2.22.11.9
Seeking ratio, punishment vs. effort0.10.30.8-0.30.30.9-0.5-0.50.5-0.6-0.7
Retroperitoneal fat weight1.88.39.13.0-2.9-3.02.62.9-2.72.92.9
Reaction time number correct0.00.10.3-0.30.50.20.0-0.2-0.20.40.3
Reaction time mean minus median0.32.13.1-1.71.81.4-1.2-1.61.3-1.3-1.2
Reaction time mean minus median AUC0.64.05.6-2.12.41.9-1.9-2.21.9-1.9-1.7
Reaction time num false alarms0.30.51.0-0.91.00.3-0.6-1.00.5-0.5-0.8
Reaction time num false alarms AUC0.20.40.8-0.90.90.2-0.5-0.80.5-0.6-0.8
Reaction time trials correct on left0.00.10.3-0.30.50.20.0-0.2-0.20.40.3
Reaction time trials on left0.00.10.4-0.40.60.3-0.0-0.3-0.10.30.2
Reaction time mean1.12.53.8-1.91.91.6-1.1-1.81.4-1.5-1.4
Reaction time mean AUC1.02.43.7-1.91.81.6-1.1-1.71.4-1.5-1.3
Median of all reaction times1.42.23.3-1.81.81.5-1.0-1.71.2-1.3-1.3
Reaction time omissions2.74.37.2-2.72.71.9-1.8-2.01.8-1.8-1.8
Reaction time false alarm rate0.30.40.8-0.50.50.1-0.6-0.70.6-0.7-0.9
Reaction time premature initiation rate5.07.810.4-3.22.93.0-2.4-2.42.8-2.8-2.7
Reaction time premature initiations2.06.19.2-3.02.92.7-2.0-2.22.3-2.2-2.1
Std. dev. reaction times0.51.62.5-1.61.51.2-0.8-1.31.1-1.2-1.1
Reaction time trials completed0.00.10.4-0.40.60.3-0.0-0.3-0.10.30.2
Reaction time trials AUC0.00.10.4-0.40.60.4-0.1-0.3-0.00.20.1
Run reversals in cocaine runway, females0.20.20.5-0.70.40.50.40.20.0-0.4-0.4
Run reversals in cocaine runway, males0.40.50.70.5-0.7-0.40.80.7-0.80.70.7
Latency to leave start box in cocaine runway3.54.86.52.2-1.9-2.22.51.1-2.52.52.4
Latency to leave start box in cocaine runway, F2.02.44.41.3-1.2-1.42.10.4-1.91.81.8
Latency to leave start box in cocaine runway, M2.72.63.51.9-1.5-1.91.41.1-1.61.81.5
Std. dev. time between licks in bursts0.10.10.30.5-0.40.20.0-0.30.2-0.3-0.2
Total sessions with >9 infusions0.10.10.20.4-0.3-0.40.20.1-0.30.40.5
Short access day 1 total inactive lever presses0.61.21.81.0-1.2-1.31.01.4-0.90.91.0
Short access day 10 total inactive lever presses0.32.12.71.3-1.5-1.31.51.6-1.51.41.5
Short access day 1 total infusions0.10.30.7-0.40.70.4-0.8-0.60.4-0.4-0.2
Short access day 10 total infusions0.20.30.7-0.20.60.5-0.8-0.60.7-0.4-0.3
Short access total infusions0.10.20.4-0.10.40.2-0.6-0.70.5-0.3-0.2
Short access day 1 locomotion1.01.72.41.3-1.5-1.21.11.5-1.41.01.2
Short access day 10 total locomotion0.62.33.71.9-1.3-1.71.21.0-1.51.81.5
Short access total locomotion1.21.82.41.6-1.5-1.31.41.1-1.41.31.2
One hour access (0.3 mA shock)0.40.40.80.30.20.5-0.9-0.90.8-0.6-0.6
Compulsive drug intake1.11.62.31.5-1.5-0.91.21.3-1.11.11.3
One hour access (shock baseline)0.71.92.3-1.11.21.3-1.5-1.31.5-1.5-1.5
Social response proportion0.20.31.1-0.2-0.4-0.60.71.0-0.20.20.3
Social responses2.33.04.41.1-1.8-1.82.02.1-1.81.51.6
Social time0.20.41.4-1.20.20.70.30.90.0-0.5-0.2
Soleus weight0.20.51.2-1.10.80.7-0.6-0.10.8-0.8-0.7
Bone: stiffness0.30.50.90.4-0.1-0.60.9-0.1-0.80.91.0
Tibialis anterior weight1.13.87.0-2.62.42.2-1.6-1.41.7-1.7-1.7
Time to tail flick, vehicle, before self-admin0.91.11.8-0.90.91.0-1.0-1.01.1-1.3-1.3
Time to tail flick, vehicle, after self-admin2.55.06.32.4-2.3-2.52.01.8-2.32.22.3
Time to tail flick, test, before self-admin0.30.31.40.20.20.5-0.5-1.20.4-0.4-0.3
Time to tail flick, test, after self-admin2.83.04.31.7-1.7-2.11.51.7-1.71.61.7
Delta time to tail flick, vehicle, before/after SA0.80.91.40.4-0.5-1.00.81.0-1.11.21.2
Delta time to tail flick, test, before/after SA0.70.91.50.6-0.7-1.20.81.2-0.90.90.9
Tibia length0.00.00.20.1-0.0-0.40.1-0.3-0.00.10.0
Ambulatory time before self-admin0.10.20.4-0.30.0-0.10.30.6-0.60.40.4
Ambulatory time after self-admin0.00.00.2-0.10.10.00.1-0.4-0.20.20.2
Bone: tissue strength2.52.63.61.2-1.6-1.61.71.9-1.71.41.6
Total heroin consumption0.20.20.6-0.30.40.5-0.8-0.20.4-0.5-0.5
Bone: trabecular number0.00.10.2-0.40.40.40.10.4-0.10.10.0
Bone: trabecular spacing0.10.10.50.20.0-0.10.0-0.70.1-0.00.1
Bone: trabecular thickness0.81.12.1-0.91.01.5-1.1-1.01.0-0.9-1.1
Bone: trabecular tissue density0.71.31.81.0-1.0-0.61.21.1-1.31.31.2
Water consumed over 24 hours0.61.11.4-1.11.11.1-0.9-0.91.0-1.0-1.2
Number of responses in last shaping day0.40.50.80.7-0.6-0.90.70.1-0.50.70.9