Hub : Genes

LOC134481483

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression LOC134481483 0.63 0.12 0.0e+00 0.34 0.38 0.36 0.36 1.6e-28 9.8e-32 2.2e-30 2.0e-30
2 BLA gene expression LOC134481483 0.42 0.12 0.0e+00 0.22 0.28 0.26 0.28 8.6e-12 4.8e-15 4.9e-14 6.5e-15
3 pVTA intron excision ratio chr13_35111875_35113956 0.14 0.07 1.0e-08 0.1 0.1 0.06 0.09 4.1e-08 3.3e-08 2.3e-05 1.1e-07
4 Brain gene expression LOC134481483 0.13 0.07 9.2e-12 0.13 0.11 0.09 0.12 8.9e-12 2.4e-10 1.5e-08 6.1e-11
5 pVTA intron excision ratio chr13_35128262_35130575 0.05 0.04 2.6e-03 0 0.01 0 0 1.1e-01 3.0e-02 3.1e-01 1.7e-01
6 pVTA intron excision ratio chr13_35130689_35130901 0.04 0.03 4.5e-03 0 0.01 0 -0 1.2e-01 9.7e-02 1.2e-01 4.4e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6
Bone: apparent density0.30.51.20.60.40.10.61.1-1.1
Area under the delay curve1.11.32.8-1.2-1.01.0-1.0-1.7-0.6
BMI with tail2.48.210.7-2.8-3.13.3-2.5-2.4-3.0
BMI without tail0.61.92.3-1.2-1.51.5-1.5-1.2-1.4
Body weight0.62.43.9-1.4-1.81.9-1.2-0.8-2.0
Weight adjusted by age0.50.71.1-0.9-0.80.9-0.6-1.1-0.8
Bone surface0.50.92.6-0.6-0.91.2-0.6-0.2-1.6
Bone volume0.20.31.00.30.20.20.40.6-1.0
Breakpoint value in progressive ratio session0.10.10.4-0.10.4-0.40.0-0.30.6
Number of licking bursts0.10.20.7-0.4-0.10.1-0.1-0.80.1
Context. condit. distance diff. score0.20.30.7-0.4-0.2-0.1-0.5-0.70.8
Locomotion velocity, session 11.41.53.6-1.4-0.90.6-1.4-1.90.6
Locomotion distance, session 10.30.41.5-0.10.4-0.6-0.1-0.61.2
Locomotion velocity, session 21.21.32.11.21.4-1.21.30.90.8
Locomotion distance, session 20.00.10.20.20.4-0.20.3-0.1-0.1
Locomotion velocity, session 30.40.52.00.40.4-0.80.20.21.4
Locomotion distance, session 30.10.10.4-0.1-0.60.4-0.20.3-0.4
Stereotopy head waving bouts, day 30.20.20.40.50.4-0.20.60.5-0.2
Stereotopy head waving duration, day 30.20.31.20.10.4-0.60.0-0.21.1
Locomotion velocity, session 70.80.94.40.20.2-0.9-0.4-0.12.1
Locomotion distance, session 70.10.10.2-0.3-0.20.0-0.3-0.30.5
Stereotopy head waving bouts, day 70.80.91.31.11.1-1.10.80.80.8
Stereotopy head waving duration, day 70.30.41.00.50.6-0.80.20.21.0
Locomotion velocity, session 80.80.94.00.20.4-1.0-0.3-0.52.0
Locomotion distance, session 80.10.10.40.10.2-0.4-0.1-0.30.6
Degree of sensitization distance0.10.10.5-0.40.1-0.0-0.3-0.70.4
Degree of sensitization stereotypy1.11.21.61.31.3-1.20.91.00.9
Conditioned locomotion0.20.30.5-0.7-0.50.5-0.4-0.6-0.2
Cocaine response after cond. corrected3.84.68.6-2.4-2.11.5-2.6-2.90.1
Cocaine response after cond. not corrected4.25.09.7-2.4-2.11.3-2.8-3.10.7
Cocaine response before conditioning0.20.20.30.40.4-0.50.30.30.6
Saline control response0.40.50.80.60.9-0.80.80.40.7
Bone: connectivity density0.50.82.3-0.4-0.81.0-0.60.2-1.5
Bone: cortical apparent density1.01.32.31.21.4-0.91.51.30.0
Bone: cortical area1.01.62.31.51.2-1.31.11.41.0
Bone: cortical porosity0.10.10.2-0.1-0.40.2-0.50.1-0.1
Bone: cortical porosity0.10.10.2-0.0-0.2-0.1-0.5-0.00.4
Bone: cortical thickness1.22.02.71.71.3-1.41.41.61.0
Bone: cortical thickness1.82.23.11.71.5-1.51.31.81.0
Bone: cortical tissue density0.81.12.01.01.3-0.81.41.1-0.0
Condit. Reinf. active minus inactive responses1.21.32.0-1.1-1.11.4-1.0-0.6-1.4
Condit. Reinf. active-inactive response ratio0.10.10.2-0.3-0.30.0-0.4-0.20.4
Condit. Reinf. active responses1.21.54.1-1.0-1.01.5-0.7-0.5-2.0
Condit. Reinf. inactive responses1.01.25.1-0.5-0.51.2-0.2-0.2-2.3
Incentive salience index mean0.80.93.3-0.6-0.71.2-0.40.0-1.8
Condit. Reinf. lever presses0.40.52.3-0.2-0.30.8-0.10.2-1.5
Condit. Reinf. active minus inactive responses4.86.27.9-2.6-2.82.6-2.6-2.5-1.7
Condit. Reinf. active-inactive response ratio4.14.85.8-2.4-2.32.2-2.2-2.4-1.4
Condit. Reinf. active responses4.66.58.4-2.6-2.92.8-2.5-2.4-2.1
Condit. Reinf. inactive responses0.70.92.1-0.6-1.11.2-0.6-0.2-1.4
Condit. Reinf. lever presses0.70.91.6-0.9-1.11.0-1.3-0.7-0.6
Condit. Reinf. lever reinforcers received4.46.17.9-2.5-2.82.7-2.4-2.2-2.0
Conditioned reinforcement - actives1.42.43.3-1.6-1.61.8-1.1-1.3-1.7
Conditioned reinforcement - inactives0.30.41.00.10.30.20.90.6-1.0
Conditioned locomotion0.60.81.61.00.9-0.51.30.9-0.5
Patch foraging indifference point 0 sec3.56.58.92.72.5-3.02.11.83.0
Patch foraging indifference point AUC1.31.94.31.61.4-0.92.11.3-0.3
Delay disc. indifference point, 0s delay0.30.30.80.50.9-0.70.30.40.3
Delay disc. indifference point, 16s delay6.06.68.9-2.8-2.62.6-2.5-3.0-1.7
Delay disc. indifference point, 2s delay2.42.74.51.41.8-2.01.31.02.1
Delay disc. indifference point, 24s delay0.50.61.5-0.7-0.60.9-0.2-0.7-1.2
Delay disc. indifference point, 4s delay0.20.20.6-0.3-0.30.40.1-0.8-0.6
Delay disc. indifference point, 8s delay0.70.82.0-1.1-0.80.7-0.9-1.4-0.1
Indifference point function ln k0.50.92.0-0.9-0.80.3-1.4-0.90.9
Indifference point function log k0.50.92.0-0.9-0.80.3-1.4-0.90.9
Patch foraging total patch changes 0 sec3.05.77.52.62.4-2.72.11.72.6
Patch foraging total patch changes 12 sec4.76.17.72.82.6-2.62.72.11.9
Patch foraging total patch changes 18 sec4.36.68.62.62.8-2.72.92.12.1
Patch foraging total patch changes 24 sec1.83.14.91.91.7-2.11.31.12.2
Patch foraging total patch changes 6 sec3.14.75.92.42.2-2.42.31.62.1
Patch foraging time to switch 0 sec1.02.13.3-1.8-1.41.5-1.3-1.5-1.0
Patch foraging water rate 0 sec1.12.36.31.51.0-1.80.40.82.5
Patch foraging water rate 12 sec0.30.71.31.10.6-0.9-0.10.80.9
Patch foraging water rate 18 sec0.40.61.80.80.4-0.9-0.60.31.4
Patch foraging water rate 24 sec0.60.92.1-0.8-1.00.5-1.5-1.10.5
Patch foraging water rate 6 sec0.30.51.20.80.2-0.7-0.40.51.1
Seeking ratio, delayed vs. immediate footshock0.30.41.00.60.4-0.70.6-0.31.0
Distance traveled before self-admin1.62.13.51.51.7-1.51.90.90.8
Distance traveled after self-admin3.24.05.42.22.3-2.02.22.00.9
Extensor digitorum longus weight0.21.01.60.91.0-0.31.31.2-0.9
Bone: elastic displacement0.50.61.0-0.8-0.90.8-1.0-0.6-0.4
Bone: elastic work0.81.11.91.00.9-1.20.60.91.4
Bone: endosteal estimation0.00.10.10.30.2-0.3-0.10.00.3
Bone: endosteal perimeter0.00.10.2-0.2-0.1-0.0-0.4-0.50.2
Epididymis fat weight2.06.78.2-2.7-2.72.9-2.0-2.6-2.5
Delta time in closed arm before/after self-admin4.94.57.6-2.5-2.22.0-1.9-2.8-1.0
Delta time in open arm before/after self-admin3.83.76.91.92.1-1.62.62.10.5
Diff in mean of infusions in LGA sessions0.20.20.70.0-0.2-0.2-0.9-0.20.8
Delay discount exponential model param0.91.02.61.10.9-0.90.81.60.5
Extinction: sum of active levers before priming0.50.51.00.50.9-0.71.00.70.5
Active lever presses in extinction session 61.61.63.11.41.3-1.01.81.3-0.0
Bone: final force2.13.34.12.01.7-2.01.41.81.8
Bone: final moment2.13.34.32.11.7-2.01.41.81.8
Food consumed during 24 hour testing period0.00.00.1-0.1-0.10.2-0.1-0.1-0.2
Glucose3.75.87.6-2.6-2.52.5-2.2-2.8-1.7
Heart weight0.81.21.7-1.0-1.31.1-1.3-1.0-0.7
Delay discount hyperbolic model param0.60.72.10.90.6-0.60.71.40.1
Intermittent access intake day 1-15 change0.00.10.4-0.3-0.10.10.30.6-0.0
Intermittent access intake escalation0.10.20.70.00.2-0.30.60.90.5
Intermittent access intake escalation 20.10.20.50.10.2-0.40.40.40.7
Intermitt. access day 1 inactive lever presses0.41.63.40.91.5-0.81.51.9-0.3
Intermitt. access day 15 inactive lever presses0.30.72.0-0.9-0.30.90.30.4-1.4
Intermitt. access escalation Index0.00.00.10.30.3-0.30.00.10.1
Intermittent access day 1 total infusions0.10.20.3-0.4-0.50.5-0.5-0.5-0.4
Intermittent access day 15 total infusions0.10.20.60.20.3-0.30.70.80.1
Intermittent access terminal intake (last 3 days)0.10.10.20.00.2-0.30.40.50.4
Intermittent access total infusions0.10.10.1-0.3-0.20.30.10.0-0.4
Intermittent access day 1 locomotion0.81.01.70.91.3-1.11.01.10.5
Intermittent access day 15 total locomotion0.20.40.50.50.7-0.70.40.60.6
Intermittent access total locomotion1.21.42.11.01.4-1.31.01.11.1
Intermittent access standard deviation0.10.20.9-1.0-0.30.30.2-0.20.2
Left kidney weight0.62.75.01.51.6-0.42.21.8-1.8
Right kidney weight0.62.75.01.71.7-0.92.22.0-0.8
Cocaine induced anxiety0.30.40.5-0.7-0.60.7-0.5-0.2-0.7
Post-drug Anxiety0.40.40.8-0.9-0.70.7-0.9-0.3-0.4
Baseline Anxiety0.00.00.2-0.2-0.10.1-0.4-0.10.0
Tail length0.31.21.61.21.0-1.30.51.21.2
Length with tail0.00.10.30.40.2-0.40.30.60.4
Length without tail0.10.40.7-0.7-0.80.8-0.4-0.3-0.7
Times rat made contact with spout0.70.91.41.01.0-0.81.11.20.3
Lifetime Intake0.10.10.2-0.3-0.10.30.20.0-0.5
Liver weight, left0.61.02.71.10.9-0.51.01.6-0.4
Liver weight, right0.20.31.1-0.00.00.40.70.3-1.1
Locomotor activity0.40.73.0-0.2-0.40.90.10.1-1.7
Locomotor testing distance0.20.31.40.00.10.40.20.2-1.2
Locomotor testing rearing0.20.41.10.40.40.10.60.6-1.1
Locomotion in novel chamber0.50.71.70.50.8-1.0-0.50.61.3
Locomotion in novel chamber post-restriction0.10.10.20.10.3-0.3-0.5-0.00.4
Fecal boli incidents, locomotor time 13.04.46.3-2.2-2.02.5-1.3-1.9-2.5
Change in fecal boli incidents, locomotor task1.61.62.71.41.3-1.31.01.60.8
Time >=10cm from walls, locomotor time 10.20.20.40.2-0.00.20.60.6-0.6
Bouts of movement, locomotor time 10.40.51.4-0.6-0.40.6-1.2-0.5-0.7
Total resting periods, locomotor time 11.01.12.4-0.9-0.91.1-1.5-0.6-1.1
Rest time, locomotor task time 11.21.54.1-1.0-1.11.1-2.0-0.9-0.8
Distance moved, locomotor task time 11.62.33.61.11.6-1.71.80.61.9
Vertical activity count, locomotor time 12.76.48.12.52.8-2.82.61.82.5
Time >=10cm from walls, locomotor time 20.20.20.60.50.0-0.10.80.7-0.2
Bouts of movement, locomotor time 20.91.42.0-1.4-1.01.2-1.1-1.4-0.9
Total resting periods, locomotor time 20.81.41.8-1.3-0.91.3-0.9-1.3-1.3
Rest time, locomotor task time 21.41.82.3-1.5-1.31.5-1.5-1.0-1.3
Distance moved, locomotor task time 24.45.36.52.42.4-2.52.51.72.1
Vertical activity count, locomotor time 22.53.44.42.11.9-2.12.01.31.6
Light reinforcement 10.30.73.30.1-0.20.7-0.00.4-1.8
Light reinforcement 21.21.94.1-1.1-1.41.7-1.1-0.3-2.0
Bone: marrow area0.10.10.20.50.3-0.50.00.20.4
Bone: maximum diameter0.20.40.70.80.7-0.70.60.70.3
Bone: maximum force3.05.36.82.52.2-2.61.72.22.5
Bone: maximum moment2.95.06.52.52.1-2.51.72.12.4
Mean time between licks in bursts2.35.77.4-2.7-2.72.4-2.6-2.5-1.1
Mean num. licks in bursts0.40.61.90.90.6-0.50.71.40.1
Cd content in liver0.10.10.2-0.4-0.20.2-0.4-0.40.1
Co content in liver1.11.32.6-1.0-1.61.0-1.6-0.7-0.1
Cu content in liver3.84.57.62.32.1-1.92.42.80.7
Fe content in liver0.10.10.40.30.1-0.4-0.10.00.6
K content in liver0.30.30.50.60.3-0.10.60.7-0.5
Mg content in liver0.10.10.20.40.1-0.10.20.4-0.1
Mn content in liver1.11.22.01.21.1-0.81.41.40.0
Na content in liver3.13.34.2-1.8-1.92.0-1.7-1.4-1.9
Rb content in liver0.60.71.6-0.7-1.20.8-1.3-0.5-0.2
Se content in liver0.20.31.1-0.2-0.40.60.1-0.2-1.0
Sr content in liver2.42.12.8-1.4-1.51.7-1.2-1.1-1.6
Zn content in liver0.40.52.2-0.3-0.10.70.30.1-1.5
Bone: minimum diameter0.30.50.80.90.5-0.80.20.70.8
Time in familiar zone, hab. session 11.01.01.8-1.0-0.80.3-1.3-1.30.8
Time in novel zone, hab. session 10.40.41.80.1-0.00.50.40.6-1.3
Total zone transitions, hab. session 10.10.10.30.00.2-0.30.1-0.10.6
Total locomotion distance, hab. session 10.00.00.10.00.3-0.10.4-0.0-0.1
Locomotion velocity, hab. session 10.20.30.50.40.7-0.50.70.40.2
Time in familiar zone, hab. session 21.61.72.9-1.2-1.00.2-1.7-1.71.4
Time in novel zone, hab. session 20.90.92.40.60.50.21.11.1-1.6
Total zone transitions, hab. session 20.00.00.10.30.2-0.20.20.10.1
Total locomotion distance, hab. session 20.20.20.60.40.5-0.10.80.4-0.6
Locomotion velocity, hab. session 20.30.41.00.70.7-0.41.00.6-0.4
Novel to familiar place preference ratio0.30.31.50.0-0.00.50.30.3-1.2
Novelty place preference0.30.41.20.30.30.20.60.6-1.1
Time in novel zone, NPP test0.30.41.10.30.30.20.70.7-1.0
Total zone transitions, NPP test0.71.01.3-1.1-1.10.9-1.1-1.1-0.4
Total locomotion distance, NPP test0.30.41.9-0.4-0.30.70.1-0.1-1.4
Locomotion velocity, NPP test0.30.41.6-0.5-0.40.8-0.1-0.2-1.3
Intraocular pressure0.30.51.2-0.7-0.50.8-0.1-0.5-1.1
Delta distance traveled before/after self-admin0.40.40.90.70.6-0.60.50.90.3
Delta ambulatory time before/after self-admin0.20.20.70.40.5-0.50.20.90.3
Parametrial fat weight2.56.07.7-2.5-2.42.8-2.2-2.0-2.7
Pavlov. Cond. lever latency0.10.10.3-0.4-0.20.1-0.3-0.50.3
Pavlov. Cond. magazine entry latency0.00.00.00.0-0.10.0-0.10.00.0
Pavlov. Cond. change in total contacts0.50.62.50.2-0.20.60.40.6-1.6
Pavlov. Cond. index score0.00.10.10.30.1-0.20.10.30.1
Pavlov. Cond. latency score0.00.00.10.30.0-0.10.00.2-0.0
Pavlov. Cond. lever contacts0.20.30.60.70.4-0.30.50.8-0.3
Pavlov. Cond. magazine entry number0.10.10.2-0.4-0.20.3-0.3-0.4-0.3
Pavlov. Cond. intertrial magazine entries0.40.50.8-0.8-0.70.7-0.9-0.7-0.4
Pavlov. Cond. lever-magazine prob. diff.0.10.20.30.50.4-0.30.40.50.0
Pavlov. Cond. response bias0.10.10.30.40.3-0.10.40.5-0.2
Pavlov. Cond. lever latency0.40.61.20.50.8-0.90.60.31.1
Pavlov. Cond. magazine entry latency0.10.10.30.20.1-0.30.00.10.6
Pavlov. Cond. change in total contacts0.91.52.0-1.2-1.31.4-1.2-0.8-1.3
Pavlov. Cond. index score0.10.20.3-0.3-0.50.5-0.4-0.1-0.6
Pavlov. Cond. latency score0.00.00.10.1-0.10.1-0.10.3-0.2
Pavlov. Cond. lever contacts0.40.61.0-0.6-0.80.9-0.7-0.4-1.0
Pavlov. Cond. magazine entry number0.00.00.1-0.10.0-0.1-0.1-0.10.3
Pavlov. Cond. intertrial magazine entries1.11.62.2-1.4-1.41.2-1.5-1.3-0.7
Pavlov. Cond. lever-magazine prob. diff.0.10.20.3-0.3-0.50.5-0.4-0.1-0.5
Pavlov. Cond. response bias0.40.51.2-0.6-0.70.9-0.5-0.4-1.1
Time in closed arm before self-admin0.91.22.71.21.0-1.10.41.60.8
Time in closed arm after self-admin0.30.30.7-0.5-0.60.4-0.8-0.7-0.1
Time in open arm before self-admin1.01.12.2-0.9-1.10.7-1.5-1.40.1
Time in open arm after self-admin1.11.22.51.41.0-0.91.61.10.2
Bone: periosteal estimation0.40.81.11.00.9-1.00.50.71.0
Bone: periosteal perimeter0.20.31.40.30.3-0.7-0.1-0.11.2
Bone: post-yield work0.20.30.6-0.3-0.60.3-0.8-0.50.2
Progressive ratio test 1 active lever presses0.91.11.6-1.2-1.21.3-0.6-0.8-1.1
Progressive ratio test 1 breakpoint1.01.31.8-1.3-1.21.3-0.7-0.9-1.2
Progressive ratio test 1 inactive lever presses0.20.30.8-0.00.50.00.90.7-0.7
Progressive ratio test 2 active lever presses0.00.00.1-0.1-0.30.1-0.2-0.20.1
Progressive ratio test 2 breakpoint0.00.00.1-0.1-0.30.1-0.1-0.10.2
Progressive ratio test 2 inactive lever presses0.71.22.21.01.1-0.91.21.50.3
Incentive Sensitization - Responses0.10.10.20.1-0.2-0.2-0.4-0.10.5
Incentive Sensitization - Breakpoint0.10.10.20.3-0.0-0.3-0.20.10.5
Sum of active levers in priming session hrs 5-61.81.72.51.41.6-1.31.41.40.5
Progressive ratio0.60.92.40.90.8-1.20.40.31.6
Food seeking constrained by brief footshock0.60.71.21.10.5-0.80.61.00.7
Seeking ratio, punishment vs. effort0.20.31.0-0.0-0.50.60.20.2-1.0
Retroperitoneal fat weight7.933.743.2-6.0-6.66.0-6.1-5.9-3.8
Reaction time number correct0.30.51.2-0.5-0.70.5-1.1-0.9-0.2
Reaction time mean minus median2.66.48.9-3.0-2.42.8-1.9-2.6-2.3
Reaction time mean minus median AUC2.87.29.8-3.1-2.72.8-2.4-2.9-1.9
Reaction time num false alarms0.91.22.41.20.8-1.30.70.91.5
Reaction time num false alarms AUC1.11.72.21.51.2-1.51.11.21.4
Reaction time trials correct on left0.30.51.2-0.5-0.70.5-1.1-0.9-0.2
Reaction time trials on left0.30.61.3-0.5-0.70.6-1.1-1.0-0.2
Reaction time mean1.01.73.7-1.5-1.01.6-0.4-0.8-1.9
Reaction time mean AUC1.42.24.2-1.7-1.21.8-0.6-1.1-2.0
Median of all reaction times0.40.61.9-0.8-0.40.90.0-0.2-1.4
Reaction time omissions0.81.21.8-1.3-1.21.3-0.5-1.2-1.0
Reaction time false alarm rate0.91.31.41.21.0-1.21.21.11.1
Reaction time premature initiation rate0.20.30.7-0.5-0.50.7-0.3-0.2-0.9
Reaction time premature initiations0.20.40.5-0.6-0.60.7-0.7-0.5-0.6
Std. dev. reaction times2.03.65.3-2.3-1.92.2-1.1-1.8-2.0
Reaction time trials completed0.30.61.3-0.5-0.70.6-1.1-1.0-0.2
Reaction time trials AUC0.30.61.5-0.5-0.70.5-1.2-1.0-0.1
Run reversals in cocaine runway, females0.80.82.2-0.6-0.6-0.0-0.7-1.51.2
Run reversals in cocaine runway, males0.00.00.10.1-0.1-0.0-0.10.30.1
Latency to leave start box in cocaine runway0.20.20.80.4-0.00.2-0.10.4-0.9
Latency to leave start box in cocaine runway, F0.20.31.0-0.1-0.40.4-1.0-0.2-0.4
Latency to leave start box in cocaine runway, M1.31.22.31.10.8-0.31.51.3-1.0
Std. dev. time between licks in bursts2.12.84.2-1.8-2.11.6-1.9-1.6-0.7
Total sessions with >9 infusions0.10.10.3-0.6-0.00.30.3-0.0-0.3
Short access day 1 total inactive lever presses0.40.50.90.60.9-0.30.80.9-0.7
Short access day 10 total inactive lever presses2.25.37.8-2.8-1.92.5-2.1-2.0-2.3
Short access day 1 total infusions0.00.00.0-0.20.2-0.0-0.2-0.00.0
Short access day 10 total infusions0.10.10.4-0.20.3-0.10.7-0.10.1
Short access total infusions0.30.40.6-0.8-0.50.7-0.1-0.5-0.8
Short access day 1 locomotion0.10.20.8-0.9-0.00.3-0.4-0.1-0.1
Short access day 10 total locomotion0.61.01.50.61.2-1.20.90.91.2
Short access total locomotion0.10.10.2-0.40.30.00.40.3-0.2
One hour access (0.3 mA shock)1.01.11.6-0.9-1.11.2-0.9-0.9-1.3
Compulsive drug intake0.40.52.5-0.2-0.10.70.1-0.3-1.6
One hour access (shock baseline)0.10.10.4-0.1-0.4-0.0-0.4-0.10.6
Social response proportion0.30.41.80.1-0.0-0.50.0-0.41.3
Social responses0.20.20.90.30.2-0.50.10.00.9
Social time0.50.71.8-0.8-0.70.3-1.3-0.90.6
Soleus weight1.44.26.72.12.3-1.52.62.5-0.1
Bone: stiffness2.13.44.52.11.9-2.01.61.91.5
Tibialis anterior weight0.10.20.5-0.4-0.30.5-0.3-0.4-0.7
Time to tail flick, vehicle, before self-admin0.30.31.30.30.00.30.00.5-1.1
Time to tail flick, vehicle, after self-admin0.00.00.1-0.1-0.10.2-0.1-0.1-0.3
Time to tail flick, test, before self-admin1.51.53.31.11.0-1.11.21.80.9
Time to tail flick, test, after self-admin0.10.10.20.40.1-0.20.20.40.2
Delta time to tail flick, vehicle, before/after SA0.20.10.4-0.6-0.30.2-0.1-0.60.2
Delta time to tail flick, test, before/after SA3.33.45.8-1.9-1.91.8-1.7-2.4-1.2
Tibia length0.10.20.4-0.1-0.70.2-0.6-0.10.3
Ambulatory time before self-admin1.42.03.61.61.5-1.41.90.90.9
Ambulatory time after self-admin3.13.75.32.32.0-1.82.12.00.8
Bone: tissue strength0.10.10.3-0.3-0.50.3-0.5-0.50.0
Total heroin consumption1.01.12.10.91.5-1.21.20.80.7
Bone: trabecular number0.40.71.50.80.9-0.51.01.2-0.5
Bone: trabecular spacing1.62.13.8-1.5-1.50.9-1.7-2.00.5
Bone: trabecular thickness5.26.510.52.92.6-2.22.83.20.7
Bone: trabecular tissue density1.42.02.81.51.7-1.51.61.20.9
Water consumed over 24 hours1.11.51.81.31.4-1.21.31.30.7
Number of responses in last shaping day0.10.10.4-0.20.5-0.20.60.20.2