Hub : Genes

LOC134480722

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression LOC134480722 0.31 0.12 1.9e-04 0.01 0.17 0.11 0.08 1.7e-01 8.4e-05 1.2e-03 5.4e-03
2 BLA gene expression LOC134480722 0.71 0.08 0.0e+00 0.4 0.39 0.41 0.42 7.6e-23 9.6e-22 1.3e-23 3.5e-24
3 PL gene expression LOC134480722 0.68 0.08 0.0e+00 0.45 0.44 0.44 0.3 5.4e-54 6.0e-53 5.0e-53 6.9e-33
4 IL gene expression LOC134480722 0.72 0.09 8.9e-13 0.38 0.36 0.35 0.38 3.0e-10 1.4e-09 3.8e-09 5.4e-10
5 NAcc gene expression LOC134480722 0.13 0.05 1.7e-16 0.12 0.12 0.13 0.04 2.8e-18 6.2e-18 1.0e-19 5.1e-07
6 OFC gene expression LOC134480722 0.3 0.12 1.2e-03 0.06 0.03 0.02 0.06 1.8e-02 7.6e-02 1.1e-01 1.8e-02
7 Brain gene expression LOC134480722 0.44 0.1 0.0e+00 0.37 0.33 0.36 0.17 2.5e-36 6.2e-32 2.9e-35 1.2e-15
8 IC gene expression LOC134480722 0.39 0.12 7.1e-11 0.29 0.23 0.24 0.13 1.3e-12 4.6e-10 1.8e-10 3.9e-06
9 pVTA gene expression LOC134480722 0.22 0.08 1.9e-14 0.16 0.18 0.17 0.15 1.3e-12 2.7e-14 7.1e-14 5.1e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.00.00.3-0.50.00.1-0.1-0.10.1-0.1-0.0-0.2
Area under the delay curve0.60.91.2-0.30.9-1.1-1.0-1.1-1.1-1.0-0.91.0
BMI with tail0.10.52.11.0-0.30.20.10.70.20.10.5-1.4
BMI without tail0.10.32.01.40.2-0.2-0.2-0.4-0.2-0.20.1-0.1
Body weight0.10.31.01.00.6-0.3-0.4-0.8-0.3-0.30.10.3
Weight adjusted by age0.10.40.80.90.4-0.7-0.6-0.7-0.7-0.4-0.50.3
Bone surface3.36.416.0-4.0-2.42.52.32.22.42.32.5-1.7
Bone volume1.83.59.4-3.1-1.81.81.71.61.81.71.8-1.2
Breakpoint value in progressive ratio session1.52.73.21.11.7-1.6-1.7-1.8-1.6-1.6-1.61.8
Number of licking bursts0.61.95.3-2.3-1.21.31.31.41.31.21.0-0.8
Context. condit. distance diff. score0.20.21.11.10.3-0.4-0.3-0.3-0.4-0.3-0.70.1
Locomotion velocity, session 10.10.10.2-0.4-0.10.10.3-0.20.20.30.20.4
Locomotion distance, session 10.10.21.01.00.10.10.2-0.60.20.20.10.3
Locomotion velocity, session 20.91.11.6-0.6-1.01.21.30.71.21.21.0-0.8
Locomotion distance, session 21.11.62.6-0.1-1.11.61.50.61.61.51.5-0.8
Locomotion velocity, session 30.40.51.81.30.5-0.4-0.3-0.8-0.3-0.3-0.60.8
Locomotion distance, session 31.31.52.1-0.1-1.21.31.41.01.31.41.5-1.1
Stereotopy head waving bouts, day 31.51.82.51.41.2-1.5-1.4-1.0-1.5-1.4-1.61.1
Stereotopy head waving duration, day 30.00.10.20.3-0.0-0.1-0.10.2-0.2-0.1-0.40.2
Locomotion velocity, session 72.62.93.9-0.7-1.71.92.01.41.92.01.8-1.4
Locomotion distance, session 74.86.28.3-0.8-2.52.72.92.02.72.92.9-2.4
Stereotopy head waving bouts, day 71.71.93.30.81.3-1.5-1.5-1.2-1.4-1.5-1.81.3
Stereotopy head waving duration, day 70.91.12.40.10.9-1.2-1.2-0.5-1.1-1.3-1.60.8
Locomotion velocity, session 81.31.62.2-0.7-1.31.31.41.21.31.51.4-1.0
Locomotion distance, session 81.31.92.90.2-1.41.71.70.91.61.71.3-1.2
Degree of sensitization distance0.60.60.8-0.4-0.80.90.90.50.80.90.8-0.8
Degree of sensitization stereotypy1.21.42.40.61.2-1.2-1.3-1.0-1.2-1.3-1.51.0
Conditioned locomotion0.10.10.3-0.2-0.30.20.20.50.30.20.1-0.6
Cocaine response after cond. corrected1.11.72.60.71.4-1.6-1.5-1.0-1.6-1.5-1.30.8
Cocaine response after cond. not corrected0.40.60.80.50.9-0.9-0.8-0.7-0.9-0.8-0.70.7
Cocaine response before conditioning1.61.93.0-0.3-1.41.71.70.91.71.71.6-0.6
Saline control response0.10.10.30.40.2-0.0-0.0-0.6-0.0-0.1-0.00.6
Bone: connectivity density0.50.71.8-1.3-0.70.80.60.70.80.60.7-1.1
Bone: cortical apparent density3.75.86.42.52.4-2.5-2.4-2.4-2.5-2.4-2.42.1
Bone: cortical area0.61.01.40.2-1.01.11.01.01.01.01.0-1.2
Bone: cortical porosity0.50.51.0-1.0-0.80.70.70.70.60.70.9-0.1
Bone: cortical porosity0.60.61.5-1.2-0.90.70.70.80.60.71.0-0.2
Bone: cortical thickness8.614.335.86.03.6-3.4-3.5-3.6-3.4-3.5-3.43.0
Bone: cortical thickness2.12.65.92.41.5-1.5-1.5-1.5-1.6-1.5-1.41.1
Bone: cortical tissue density3.75.96.72.42.5-2.6-2.5-2.4-2.6-2.4-2.52.1
Condit. Reinf. active minus inactive responses0.10.20.70.7-0.30.10.10.20.10.20.2-0.8
Condit. Reinf. active-inactive response ratio0.30.31.70.3-0.50.30.20.60.20.30.2-1.3
Condit. Reinf. active responses0.20.31.51.20.3-0.4-0.4-0.4-0.4-0.3-0.2-0.2
Condit. Reinf. inactive responses0.30.40.90.90.6-0.4-0.4-1.0-0.4-0.4-0.20.9
Incentive salience index mean0.10.10.50.70.1-0.2-0.3-0.2-0.2-0.2-0.2-0.4
Condit. Reinf. lever presses0.20.30.60.70.5-0.5-0.5-0.8-0.5-0.4-0.40.3
Condit. Reinf. active minus inactive responses0.50.70.9-0.4-0.90.90.90.80.90.90.9-0.7
Condit. Reinf. active-inactive response ratio0.50.91.1-0.6-1.00.91.00.81.01.11.0-0.7
Condit. Reinf. active responses0.70.91.3-0.3-1.01.11.10.81.11.11.1-0.9
Condit. Reinf. inactive responses0.10.10.20.4-0.20.40.30.10.30.30.3-0.2
Condit. Reinf. lever presses2.63.84.6-1.2-2.02.22.11.72.12.12.1-1.8
Condit. Reinf. lever reinforcers received1.21.72.3-0.5-1.31.51.51.11.51.41.4-1.2
Conditioned reinforcement - actives0.10.50.8-0.0-0.80.60.60.80.60.70.6-0.9
Conditioned reinforcement - inactives1.13.04.4-0.5-1.91.71.81.81.71.81.8-2.1
Conditioned locomotion0.00.00.10.4-0.1-0.0-0.10.1-0.0-0.00.1-0.2
Patch foraging indifference point 0 sec0.20.61.20.8-0.61.11.00.31.00.80.6-0.5
Patch foraging indifference point AUC1.53.54.0-1.3-2.02.02.02.01.92.01.8-1.9
Delay disc. indifference point, 0s delay1.51.72.10.81.4-1.3-1.3-1.5-1.3-1.4-1.41.2
Delay disc. indifference point, 16s delay0.10.10.6-0.80.1-0.3-0.2-0.3-0.2-0.2-0.20.4
Delay disc. indifference point, 2s delay1.82.03.0-0.11.4-1.6-1.4-1.7-1.6-1.4-1.31.7
Delay disc. indifference point, 24s delay0.20.31.1-1.0-0.40.40.50.30.40.50.4-0.1
Delay disc. indifference point, 4s delay2.02.13.20.21.5-1.7-1.6-1.4-1.8-1.6-1.51.3
Delay disc. indifference point, 8s delay0.71.11.50.11.0-1.2-1.1-1.1-1.2-1.1-1.11.1
Indifference point function ln k0.41.22.21.51.2-1.0-1.1-1.0-1.0-1.1-1.10.9
Indifference point function log k0.41.22.21.51.2-1.0-1.1-1.0-1.0-1.1-1.10.9
Patch foraging total patch changes 0 sec0.20.61.10.8-0.61.10.90.31.00.90.6-0.5
Patch foraging total patch changes 12 sec1.72.33.3-0.3-1.61.71.81.21.71.71.7-1.3
Patch foraging total patch changes 18 sec0.10.30.50.6-0.40.70.70.20.60.60.4-0.4
Patch foraging total patch changes 24 sec0.93.24.0-0.7-1.91.92.01.71.91.91.9-1.8
Patch foraging total patch changes 6 sec1.01.72.90.6-1.21.71.70.81.71.51.2-0.9
Patch foraging time to switch 0 sec0.00.10.3-0.50.2-0.4-0.3-0.4-0.4-0.30.10.5
Patch foraging water rate 0 sec0.00.10.30.3-0.10.40.20.10.30.2-0.1-0.6
Patch foraging water rate 12 sec0.52.02.91.41.5-1.4-1.5-1.5-1.4-1.4-1.71.0
Patch foraging water rate 18 sec0.00.10.20.40.3-0.3-0.3-0.2-0.2-0.4-0.5-0.3
Patch foraging water rate 24 sec0.30.42.21.50.5-0.4-0.4-0.4-0.4-0.5-0.6-0.3
Patch foraging water rate 6 sec1.92.83.81.91.8-1.5-1.6-1.8-1.4-1.6-1.71.5
Seeking ratio, delayed vs. immediate footshock0.00.00.1-0.3-0.1-0.1-0.10.1-0.1-0.20.2-0.3
Distance traveled before self-admin0.81.72.40.71.4-1.4-1.5-1.1-1.4-1.5-1.51.0
Distance traveled after self-admin0.00.10.3-0.4-0.10.0-0.00.20.0-0.1-0.0-0.5
Extensor digitorum longus weight0.00.10.20.20.2-0.3-0.20.1-0.3-0.10.2-0.5
Bone: elastic displacement4.45.611.03.32.3-2.1-2.2-2.4-2.1-2.2-2.22.3
Bone: elastic work1.82.37.12.71.4-1.2-1.4-1.5-1.2-1.4-1.31.0
Bone: endosteal estimation20.149.069.6-8.3-7.16.76.87.06.76.86.7-6.7
Bone: endosteal perimeter15.738.564.6-8.0-6.26.05.96.16.05.95.8-5.6
Epididymis fat weight0.31.34.22.01.1-0.6-0.7-1.8-0.6-0.7-0.61.0
Delta time in closed arm before/after self-admin2.32.22.8-0.9-1.51.71.61.41.71.61.6-1.1
Delta time in open arm before/after self-admin3.44.05.82.41.9-1.9-1.7-2.2-1.9-1.7-1.72.2
Diff in mean of infusions in LGA sessions1.32.43.01.31.5-1.7-1.6-1.5-1.7-1.5-1.71.4
Delay discount exponential model param0.81.11.40.3-1.01.21.01.11.21.11.0-1.1
Extinction: sum of active levers before priming0.60.91.40.1-1.01.11.20.81.11.21.1-0.7
Active lever presses in extinction session 60.30.30.4-0.20.5-0.6-0.5-0.7-0.6-0.5-0.70.6
Bone: final force1.21.93.9-0.5-1.51.31.41.51.21.31.4-2.0
Bone: final moment0.50.82.10.1-0.90.80.81.00.70.80.9-1.4
Food consumed during 24 hour testing period0.20.52.3-1.5-0.50.40.50.50.40.50.7-0.5
Glucose0.10.10.20.20.4-0.4-0.3-0.4-0.4-0.3-0.30.5
Heart weight0.10.20.90.3-0.40.40.6-0.00.30.60.9-0.3
Delay discount hyperbolic model param1.11.51.90.2-1.21.41.21.31.41.31.2-1.3
Intermittent access intake day 1-15 change0.63.23.81.81.8-1.9-1.8-1.7-1.9-1.8-1.61.6
Intermittent access intake escalation0.42.12.61.61.4-1.6-1.5-1.4-1.6-1.4-1.31.2
Intermittent access intake escalation 22.84.75.21.82.3-2.3-2.2-2.2-2.3-2.2-2.22.1
Intermitt. access day 1 inactive lever presses0.10.81.31.1-0.80.91.00.50.91.00.9-1.0
Intermitt. access day 15 inactive lever presses0.00.00.10.1-0.20.10.2-0.00.10.20.3-0.2
Intermitt. access escalation Index0.00.10.4-0.6-0.20.20.10.40.20.10.1-0.5
Intermittent access day 1 total infusions2.05.97.0-1.1-2.62.62.52.52.62.62.5-2.5
Intermittent access day 15 total infusions0.40.91.40.2-1.00.90.91.00.91.01.0-1.2
Intermittent access terminal intake (last 3 days)0.61.11.7-0.2-1.21.11.11.21.11.11.0-1.3
Intermittent access total infusions4.65.56.5-0.9-2.52.52.42.42.52.42.4-2.5
Intermittent access day 1 locomotion1.73.14.1-0.8-1.91.81.71.81.81.72.0-1.8
Intermittent access day 15 total locomotion0.10.21.11.0-0.40.40.30.10.40.40.4-0.4
Intermittent access total locomotion2.63.14.3-0.4-1.91.81.81.71.81.82.1-1.8
Intermittent access standard deviation0.00.20.60.1-0.30.20.30.60.20.30.2-0.8
Left kidney weight0.00.30.6-0.10.6-0.8-0.7-0.5-0.8-0.6-0.50.0
Right kidney weight0.32.23.10.81.6-1.8-1.7-1.4-1.7-1.7-1.60.8
Cocaine induced anxiety0.00.00.10.10.1-0.1-0.1-0.2-0.1-0.10.10.3
Post-drug Anxiety0.10.10.30.1-0.30.40.40.10.40.40.50.0
Baseline Anxiety0.30.50.8-0.3-0.70.90.90.50.90.90.8-0.5
Tail length0.31.64.61.11.2-0.8-0.7-2.0-0.9-0.7-0.62.1
Length with tail0.72.96.30.91.9-1.5-1.4-2.5-1.5-1.4-1.22.5
Length without tail0.73.74.81.12.2-2.0-2.0-2.1-1.9-2.0-1.82.0
Times rat made contact with spout1.41.73.50.31.3-1.2-1.2-1.5-1.2-1.2-1.11.9
Lifetime Intake5.06.27.5-1.1-2.72.62.52.72.62.62.5-2.7
Liver weight, left0.10.20.6-0.80.30.1-0.1-0.70.10.00.00.5
Liver weight, right0.30.51.31.10.7-0.6-0.6-0.7-0.6-0.7-0.60.4
Locomotor activity1.52.33.1-1.1-1.41.81.61.61.61.61.3-1.7
Locomotor testing distance0.51.21.80.0-0.91.31.20.91.21.11.0-1.3
Locomotor testing rearing0.00.10.30.4-0.30.50.50.10.40.40.1-0.4
Locomotion in novel chamber0.20.31.8-1.3-0.20.30.30.30.50.20.2-0.6
Locomotion in novel chamber post-restriction0.20.60.9-0.9-0.80.90.90.40.90.90.7-0.5
Fecal boli incidents, locomotor time 10.20.61.1-0.7-0.71.01.00.70.90.70.9-0.2
Change in fecal boli incidents, locomotor task0.70.71.20.90.8-0.9-0.9-0.8-0.9-0.7-1.10.4
Time >=10cm from walls, locomotor time 10.81.01.7-1.1-1.00.90.91.30.90.80.7-1.3
Bouts of movement, locomotor time 10.20.30.60.4-0.30.70.80.10.70.50.20.0
Total resting periods, locomotor time 10.10.10.30.4-0.10.50.5-0.10.40.30.00.3
Rest time, locomotor task time 10.50.81.20.70.9-0.8-0.7-0.8-0.9-0.9-1.11.1
Distance moved, locomotor task time 10.10.30.50.50.5-0.7-0.7-0.6-0.6-0.5-0.40.2
Vertical activity count, locomotor time 10.31.82.6-0.4-1.51.41.31.11.51.61.6-1.4
Time >=10cm from walls, locomotor time 20.00.10.50.70.10.10.0-0.30.10.1-0.10.2
Bouts of movement, locomotor time 20.31.01.51.21.0-1.0-0.9-1.1-0.9-0.9-0.91.0
Total resting periods, locomotor time 20.10.61.11.10.7-0.7-0.6-0.8-0.6-0.7-0.70.7
Rest time, locomotor task time 20.00.00.20.40.1-0.1-0.00.0-0.1-0.2-0.30.1
Distance moved, locomotor task time 20.00.10.1-0.20.2-0.3-0.3-0.4-0.2-0.2-0.10.0
Vertical activity count, locomotor time 20.00.00.10.3-0.10.20.0-0.10.20.20.3-0.1
Light reinforcement 10.10.51.60.1-0.70.60.60.80.60.60.7-1.3
Light reinforcement 21.73.84.3-1.5-2.02.02.01.92.12.02.0-2.0
Bone: marrow area19.648.167.5-8.2-7.06.76.76.96.76.86.6-6.6
Bone: maximum diameter10.721.525.9-5.1-4.74.54.54.94.54.54.5-4.5
Bone: maximum force2.44.87.1-1.5-2.32.22.22.22.12.22.3-2.7
Bone: maximum moment1.32.54.2-0.8-1.71.61.61.51.51.61.7-2.1
Mean time between licks in bursts0.21.01.6-1.3-0.91.01.00.91.01.00.9-1.0
Mean num. licks in bursts1.33.66.22.51.8-1.9-1.8-2.2-1.9-1.7-1.51.6
Cd content in liver0.30.31.51.20.5-0.4-0.2-0.6-0.3-0.3-0.40.6
Co content in liver2.12.53.41.11.7-1.7-1.8-1.3-1.6-1.8-1.61.4
Cu content in liver0.10.20.4-0.60.3-0.4-0.5-0.1-0.4-0.5-0.30.4
Fe content in liver0.10.10.50.2-0.20.50.30.10.40.30.7-0.1
K content in liver0.10.10.30.10.3-0.3-0.4-0.2-0.3-0.4-0.20.5
Mg content in liver0.00.00.1-0.20.1-0.1-0.10.0-0.1-0.20.00.2
Mn content in liver0.50.62.1-1.4-0.70.60.40.90.70.40.6-0.5
Na content in liver0.10.10.8-0.90.0-0.0-0.10.30.0-0.20.1-0.2
Rb content in liver0.20.31.1-0.1-0.50.40.40.80.30.30.4-1.0
Se content in liver0.00.00.1-0.10.1-0.2-0.20.1-0.2-0.2-0.10.2
Sr content in liver2.11.82.7-1.2-1.31.61.41.21.61.41.4-1.1
Zn content in liver1.01.21.80.51.2-1.2-1.3-0.8-1.2-1.3-1.20.7
Bone: minimum diameter7.013.519.4-4.4-3.83.63.63.73.53.63.4-3.4
Time in familiar zone, hab. session 10.10.10.30.50.2-0.1-0.1-0.4-0.1-0.1-0.00.3
Time in novel zone, hab. session 10.10.10.2-0.00.2-0.3-0.30.0-0.3-0.4-0.5-0.2
Total zone transitions, hab. session 10.20.20.90.30.6-0.4-0.3-0.9-0.3-0.3-0.20.5
Total locomotion distance, hab. session 10.10.10.20.1-0.20.30.3-0.10.40.30.2-0.5
Locomotion velocity, hab. session 10.20.30.5-0.1-0.40.70.60.10.70.60.5-0.4
Time in familiar zone, hab. session 21.01.11.30.81.1-1.1-1.1-1.2-1.1-1.1-1.00.8
Time in novel zone, hab. session 21.51.62.6-0.6-1.41.21.31.61.21.31.2-1.3
Total zone transitions, hab. session 20.30.40.7-0.2-0.50.70.70.30.80.80.8-0.5
Total locomotion distance, hab. session 20.20.20.40.1-0.40.50.50.30.70.50.5-0.6
Locomotion velocity, hab. session 20.20.30.5-0.2-0.50.50.50.40.70.50.5-0.7
Novel to familiar place preference ratio0.10.10.20.10.3-0.3-0.4-0.3-0.3-0.4-0.30.1
Novelty place preference0.00.00.1-0.10.1-0.1-0.2-0.1-0.1-0.2-0.1-0.1
Time in novel zone, NPP test0.00.00.00.10.00.0-0.1-0.00.0-0.1-0.0-0.2
Total zone transitions, NPP test0.20.30.60.4-0.30.70.7-0.20.80.70.70.2
Total locomotion distance, NPP test0.40.61.41.2-0.40.90.8-0.21.00.80.60.0
Locomotion velocity, NPP test0.20.31.51.2-0.00.40.4-0.50.50.40.20.4
Intraocular pressure1.52.43.5-1.2-1.51.71.71.31.81.61.9-1.2
Delta distance traveled before/after self-admin2.02.23.7-1.2-1.61.41.51.51.41.41.5-1.9
Delta ambulatory time before/after self-admin1.42.43.9-1.8-1.61.41.41.51.41.31.4-2.0
Parametrial fat weight0.20.50.7-0.4-0.80.70.70.70.70.80.8-0.7
Pavlov. Cond. lever latency1.41.82.4-1.3-1.41.21.41.51.21.31.2-1.4
Pavlov. Cond. magazine entry latency4.35.67.41.62.4-2.6-2.7-2.2-2.6-2.6-2.61.8
Pavlov. Cond. change in total contacts1.31.42.21.51.2-1.1-1.3-1.4-1.0-1.2-1.10.9
Pavlov. Cond. index score2.32.93.71.41.7-1.8-1.9-1.7-1.8-1.8-1.81.4
Pavlov. Cond. latency score2.73.54.31.41.9-1.9-2.1-1.9-1.9-2.0-1.91.7
Pavlov. Cond. lever contacts1.51.82.41.41.4-1.2-1.4-1.5-1.2-1.3-1.21.3
Pavlov. Cond. magazine entry number4.35.57.1-1.7-2.32.52.72.22.52.52.5-1.8
Pavlov. Cond. intertrial magazine entries0.40.51.20.2-0.70.70.90.30.80.91.1-0.4
Pavlov. Cond. lever-magazine prob. diff.2.02.43.21.21.6-1.6-1.8-1.5-1.6-1.7-1.71.2
Pavlov. Cond. response bias2.53.13.81.61.7-1.8-2.0-1.8-1.8-1.8-1.81.3
Pavlov. Cond. lever latency1.52.12.70.81.5-1.6-1.5-1.5-1.5-1.5-1.51.4
Pavlov. Cond. magazine entry latency3.24.55.4-1.4-2.22.32.32.22.22.32.3-1.8
Pavlov. Cond. change in total contacts2.25.46.3-1.3-2.42.52.52.42.42.42.4-2.3
Pavlov. Cond. index score2.94.65.7-1.4-2.22.42.32.12.32.32.3-1.9
Pavlov. Cond. latency score3.25.16.1-1.5-2.32.52.42.22.42.42.4-2.0
Pavlov. Cond. lever contacts1.32.02.6-0.8-1.51.61.51.31.51.41.5-1.3
Pavlov. Cond. magazine entry number3.84.95.91.32.2-2.4-2.4-2.3-2.3-2.3-2.32.1
Pavlov. Cond. intertrial magazine entries0.10.21.2-1.1-0.40.20.10.30.20.10.2-0.5
Pavlov. Cond. lever-magazine prob. diff.2.94.45.4-1.4-2.12.32.32.12.22.22.2-1.9
Pavlov. Cond. response bias1.92.63.4-0.8-1.71.81.71.61.71.71.6-1.5
Time in closed arm before self-admin0.61.01.7-1.1-1.00.91.01.10.91.00.7-1.3
Time in closed arm after self-admin2.22.44.2-1.8-1.61.31.41.81.31.41.2-2.0
Time in open arm before self-admin0.50.61.10.60.9-0.6-0.8-0.9-0.6-0.8-0.71.1
Time in open arm after self-admin0.50.61.81.30.6-0.3-0.3-1.0-0.3-0.3-0.11.3
Bone: periosteal estimation10.625.129.0-5.4-5.24.94.95.14.94.94.8-5.0
Bone: periosteal perimeter5.510.917.0-4.1-3.33.33.03.43.33.03.0-3.1
Bone: post-yield work4.78.29.4-3.1-2.92.82.82.72.72.92.8-2.9
Progressive ratio test 1 active lever presses0.20.30.60.4-0.60.60.50.40.60.50.8-0.7
Progressive ratio test 1 breakpoint0.30.50.90.3-0.70.80.70.50.80.70.9-0.7
Progressive ratio test 1 inactive lever presses0.82.13.8-0.2-1.51.41.41.51.41.41.6-1.9
Progressive ratio test 2 active lever presses0.71.01.4-0.3-1.11.01.01.11.01.01.2-1.2
Progressive ratio test 2 breakpoint0.91.21.5-0.4-1.21.11.11.21.11.11.2-1.2
Progressive ratio test 2 inactive lever presses0.41.21.50.1-1.21.11.11.11.11.21.2-1.2
Incentive Sensitization - Responses0.10.20.4-0.5-0.40.30.30.60.30.30.4-0.6
Incentive Sensitization - Breakpoint0.10.20.4-0.6-0.40.20.20.60.20.20.3-0.6
Sum of active levers in priming session hrs 5-61.11.12.01.41.0-0.9-1.0-1.1-0.9-0.9-1.20.7
Progressive ratio0.92.74.1-2.0-1.61.71.71.81.71.61.5-1.2
Food seeking constrained by brief footshock0.30.41.0-0.40.6-0.6-0.6-0.3-0.6-0.7-1.00.4
Seeking ratio, punishment vs. effort0.71.72.01.21.3-1.4-1.4-1.2-1.4-1.4-1.30.9
Retroperitoneal fat weight0.10.63.61.90.40.1-0.2-1.10.1-0.1-0.10.4
Reaction time number correct0.00.00.10.3-0.00.20.1-0.20.20.10.10.0
Reaction time mean minus median0.00.00.2-0.30.0-0.1-0.0-0.30.0-0.1-0.40.2
Reaction time mean minus median AUC0.00.30.8-0.9-0.50.40.50.60.40.40.0-0.7
Reaction time num false alarms0.10.20.7-0.9-0.30.30.30.50.20.30.1-0.4
Reaction time num false alarms AUC0.10.10.9-1.0-0.20.20.20.40.20.20.1-0.2
Reaction time trials correct on left0.00.00.10.3-0.00.20.1-0.20.20.10.10.0
Reaction time trials on left0.00.00.10.2-0.10.20.2-0.10.20.20.1-0.0
Reaction time mean0.20.40.6-0.6-0.70.60.70.50.60.70.4-0.5
Reaction time mean AUC0.40.91.2-0.6-1.11.01.10.91.01.10.7-0.8
Median of all reaction times0.60.91.2-0.7-1.11.01.11.00.91.10.9-0.8
Reaction time omissions0.30.51.5-1.2-0.70.50.50.50.60.60.4-0.6
Reaction time false alarm rate0.10.10.8-0.90.0-0.1-0.10.2-0.2-0.1-0.20.0
Reaction time premature initiation rate4.16.37.62.02.6-2.6-2.6-2.8-2.6-2.6-2.62.1
Reaction time premature initiations1.13.44.61.61.9-1.8-1.9-2.1-1.8-1.8-1.91.5
Std. dev. reaction times0.00.00.1-0.3-0.10.00.1-0.20.10.1-0.30.2
Reaction time trials completed0.00.00.10.2-0.10.20.2-0.10.20.20.1-0.0
Reaction time trials AUC0.00.10.10.2-0.20.30.3-0.00.30.30.2-0.1
Run reversals in cocaine runway, females0.50.50.70.80.8-0.7-0.6-0.7-0.6-0.8-0.70.7
Run reversals in cocaine runway, males0.00.00.20.50.1-0.1-0.10.0-0.1-0.1-0.1-0.1
Latency to leave start box in cocaine runway0.71.01.71.30.9-1.0-1.1-0.7-1.2-1.1-1.00.4
Latency to leave start box in cocaine runway, F1.92.33.81.91.5-1.4-1.6-1.5-1.7-1.5-1.41.0
Latency to leave start box in cocaine runway, M0.60.61.4-0.8-0.80.50.51.20.50.40.5-1.1
Std. dev. time between licks in bursts1.32.53.4-0.4-1.51.81.81.41.81.71.7-1.6
Total sessions with >9 infusions0.10.20.50.1-0.40.20.20.60.20.20.4-0.7
Short access day 1 total inactive lever presses2.04.05.4-0.9-2.12.02.02.12.02.02.1-2.3
Short access day 10 total inactive lever presses0.21.21.5-0.4-1.11.21.20.91.21.21.2-1.2
Short access day 1 total infusions0.81.63.1-0.6-1.41.21.11.71.21.11.1-1.8
Short access day 10 total infusions2.03.45.9-1.2-2.01.81.72.21.81.71.6-2.4
Short access total infusions3.54.96.9-1.3-2.42.22.12.52.22.22.1-2.6
Short access day 1 locomotion0.10.20.70.1-0.50.40.30.60.40.30.5-0.8
Short access day 10 total locomotion0.31.31.6-1.3-1.21.01.01.31.00.91.2-1.2
Short access total locomotion0.20.20.7-0.2-0.50.30.20.70.30.20.6-0.9
One hour access (0.3 mA shock)0.80.91.4-0.4-1.00.90.91.10.90.91.1-1.2
Compulsive drug intake1.52.22.7-1.0-1.51.61.61.41.61.61.6-1.5
One hour access (shock baseline)0.10.10.3-0.3-0.40.30.30.50.30.30.4-0.4
Social response proportion0.30.30.8-0.00.6-0.6-0.7-0.5-0.6-0.7-0.90.1
Social responses0.81.01.40.81.1-1.0-1.2-0.9-1.0-1.2-1.10.3
Social time0.10.10.5-0.5-0.30.20.10.30.20.10.1-0.7
Soleus weight0.82.24.0-2.0-1.41.11.12.01.11.21.3-1.8
Bone: stiffness4.27.610.3-2.5-2.82.62.72.82.62.82.6-3.2
Tibialis anterior weight0.00.10.3-0.50.1-0.4-0.30.4-0.4-0.3-0.2-0.6
Time to tail flick, vehicle, before self-admin0.91.11.8-0.7-1.01.11.20.81.11.31.4-0.8
Time to tail flick, vehicle, after self-admin0.40.91.5-0.40.9-1.1-1.0-0.6-1.1-1.0-1.20.6
Time to tail flick, test, before self-admin0.20.30.7-0.20.5-0.3-0.4-0.8-0.3-0.5-0.50.9
Time to tail flick, test, after self-admin1.92.02.90.71.5-1.3-1.4-1.6-1.3-1.5-1.31.7
Delta time to tail flick, vehicle, before/after SA2.83.04.50.91.7-1.8-1.9-1.6-1.8-1.9-2.11.4
Delta time to tail flick, test, before/after SA0.30.30.40.70.6-0.6-0.6-0.4-0.6-0.6-0.40.6
Tibia length0.41.11.80.61.0-1.3-1.2-0.6-1.2-1.2-1.30.7
Ambulatory time before self-admin1.23.64.21.52.0-2.0-2.0-1.8-2.0-2.0-2.11.7
Ambulatory time after self-admin0.00.00.1-0.10.2-0.2-0.2-0.2-0.2-0.3-0.2-0.0
Bone: tissue strength0.50.53.11.80.4-0.5-0.5-0.4-0.4-0.4-0.4-0.1
Total heroin consumption0.10.10.1-0.20.2-0.4-0.3-0.0-0.4-0.2-0.20.3
Bone: trabecular number0.10.10.3-0.50.3-0.3-0.4-0.3-0.3-0.4-0.30.2
Bone: trabecular spacing0.00.10.40.6-0.20.10.20.20.10.20.1-0.1
Bone: trabecular thickness0.00.10.4-0.6-0.10.20.1-0.00.30.10.2-0.0
Bone: trabecular tissue density0.00.10.3-0.00.1-0.1-0.1-0.5-0.2-0.1-0.10.5
Water consumed over 24 hours0.00.10.2-0.40.1-0.1-0.0-0.4-0.1-0.0-0.00.5
Number of responses in last shaping day2.12.83.8-1.4-1.71.61.61.71.61.61.8-2.0