Hub : Genes

LOC134479342

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL isoform ratio XM_063262745.1 0.03 0.02 3.3e-03 0 0.01 0.01 0 1.2e-01 1.9e-02 5.3e-02 7.6e-02
2 NAcc intron excision ratio chr6_42650510_42746088 0.04 0.02 9.3e-07 0.03 0.04 0.04 0.04 9.2e-05 3.4e-07 5.9e-07 7.8e-07
3 NAcc gene expression LOC134479342 0.05 0.03 3.5e-06 0.04 0.04 0.02 0.04 2.7e-07 2.0e-06 1.4e-04 1.2e-06
4 PL intron excision ratio chr6_42650510_42746088 0.06 0.04 1.6e-08 0.05 0.07 0.07 0.07 3.0e-06 1.9e-08 5.1e-08 4.1e-08
5 pVTA gene expression LOC134479342 0.06 0.03 8.0e-04 0.01 0.03 0.02 0.02 5.3e-02 2.1e-03 1.6e-02 1.2e-02
6 PL intron excision ratio chr6_42650510_42668089 0.03 0.02 2.8e-04 0.02 0.03 0.02 0.02 2.0e-03 3.8e-04 1.4e-03 3.0e-03
7 BLA mRNA stability LOC134479342 0.06 0.04 2.5e-03 0.03 0.02 0 0.01 7.8e-03 4.7e-02 2.0e-01 5.6e-02
8 NAcc intron excision ratio chr6_42650510_42668089 0.02 0.01 1.6e-03 0.02 0.02 0.01 0.02 7.1e-04 1.4e-03 3.0e-03 8.7e-04
9 Brain intron excision ratio chr6_42668152_42746088 0.02 0.02 8.2e-03 0.02 0.02 0.01 0.02 8.9e-03 9.8e-03 8.7e-02 1.1e-02
10 PL mRNA stability LOC134479342 0.07 0.04 4.4e-04 0 0.03 0.02 0.01 3.3e-01 8.2e-04 1.6e-03 2.5e-02
11 NAcc intron excision ratio chr6_42668152_42746088 0.02 0.01 1.0e-03 0.01 0.01 0.01 0.01 1.6e-02 2.1e-03 3.8e-03 2.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.20.41.1-1.00.90.40.71.0-0.50.60.2-0.40.30.1
Area under the delay curve0.30.30.90.30.6-0.20.3-1.0-0.4-0.6-0.70.4-0.8-0.7
BMI with tail0.51.94.31.6-2.1-1.0-1.7-1.21.5-1.21.51.2-0.00.9
BMI without tail0.41.12.71.1-1.6-0.8-1.4-0.71.4-0.71.10.70.20.9
Body weight0.41.95.11.6-2.3-1.3-1.7-0.81.6-0.91.51.00.70.8
Weight adjusted by age0.30.41.20.8-0.50.8-0.0-0.3-0.20.1-0.6-0.41.1-1.1
Bone surface0.00.10.3-0.30.4-0.30.10.2-0.10.00.60.10.20.1
Bone volume0.40.71.8-1.21.30.61.01.1-0.80.8-0.1-0.70.4-0.2
Breakpoint value in progressive ratio session0.10.10.50.00.1-0.10.2-0.2-0.30.0-0.7-0.3-0.4-0.4
Number of licking bursts0.00.10.2-0.30.20.40.20.4-0.00.4-0.2-0.30.30.1
Context. condit. distance diff. score0.40.40.80.9-0.9-0.6-0.7-0.70.6-0.70.60.70.20.1
Locomotion velocity, session 10.80.91.91.4-0.6-1.3-0.8-1.31.0-0.90.50.90.3-0.1
Locomotion distance, session 11.21.54.60.30.90.21.10.0-0.90.8-1.9-1.01.9-2.1
Locomotion velocity, session 20.10.20.4-0.10.40.60.30.1-0.30.3-0.5-0.40.5-0.5
Locomotion distance, session 20.40.61.90.50.3-0.20.5-0.3-0.30.4-1.4-0.71.0-1.3
Locomotion velocity, session 30.10.10.30.10.5-0.40.3-0.2-0.0-0.1-0.6-0.20.3-0.5
Locomotion distance, session 30.80.81.40.9-0.8-1.2-0.9-1.01.1-1.10.61.0-0.40.6
Stereotopy head waving bouts, day 30.40.51.8-1.00.90.60.50.3-0.60.00.40.0-1.30.5
Stereotopy head waving duration, day 30.20.30.7-0.60.60.80.50.4-0.70.60.1-0.60.1-0.3
Locomotion velocity, session 70.91.02.91.7-0.7-1.5-0.8-1.60.9-0.8-0.20.60.4-0.6
Locomotion distance, session 71.11.42.41.3-1.5-1.3-1.4-1.11.5-1.21.11.1-0.30.9
Stereotopy head waving bouts, day 71.21.33.2-0.91.81.01.40.5-1.31.0-1.3-1.10.3-1.3
Stereotopy head waving duration, day 71.21.52.4-1.01.51.41.40.9-1.41.2-1.1-1.20.7-1.2
Locomotion velocity, session 82.22.75.21.9-1.6-1.3-1.7-2.31.5-2.00.91.8-1.50.8
Locomotion distance, session 80.60.93.81.1-0.1-0.70.1-0.50.10.3-1.1-0.41.9-1.5
Degree of sensitization distance0.10.10.50.1-0.70.3-0.40.10.1-0.00.60.2-0.20.5
Degree of sensitization stereotypy0.91.01.6-0.61.30.91.10.5-1.00.9-1.2-1.00.8-1.2
Conditioned locomotion0.70.83.0-1.31.7-0.01.20.9-0.60.5-1.0-0.6-0.2-0.1
Cocaine response after cond. corrected0.70.82.4-1.41.30.50.80.7-0.40.1-0.8-0.3-1.50.7
Cocaine response after cond. not corrected1.21.54.5-2.11.51.31.11.6-0.70.7-0.5-0.8-1.20.9
Cocaine response before conditioning2.02.45.0-1.71.11.91.42.2-1.42.0-0.1-1.71.6-0.5
Saline control response2.12.77.9-0.11.11.11.40.7-1.32.0-1.4-2.02.8-2.4
Bone: connectivity density0.10.10.5-0.20.3-0.4-0.00.10.1-0.10.70.2-0.20.3
Bone: cortical apparent density0.60.81.80.5-0.8-1.0-1.0-0.41.2-0.71.30.8-0.01.1
Bone: cortical area0.10.20.6-0.60.50.10.40.8-0.20.4-0.2-0.30.7-0.1
Bone: cortical porosity2.02.25.6-2.42.02.01.51.8-1.21.2-0.4-1.1-0.70.4
Bone: cortical porosity1.71.84.6-2.11.82.01.31.5-1.21.1-0.2-1.0-0.70.4
Bone: cortical thickness0.30.43.30.4-0.2-0.50.00.30.20.4-0.3-0.31.8-0.6
Bone: cortical thickness1.01.23.3-0.91.10.21.11.4-0.51.2-1.1-1.21.8-0.8
Bone: cortical tissue density0.81.02.10.6-0.9-1.1-1.2-0.61.4-0.91.51.0-0.21.2
Condit. Reinf. active minus inactive responses0.40.51.21.1-1.0-0.4-0.8-0.70.6-0.50.70.50.5-0.1
Condit. Reinf. active-inactive response ratio1.11.22.21.5-1.5-1.2-1.3-1.11.1-0.91.31.00.30.2
Condit. Reinf. active responses0.10.10.50.5-0.30.4-0.1-0.3-0.10.10.0-0.00.7-0.6
Condit. Reinf. inactive responses0.10.10.6-0.30.40.80.40.1-0.40.0-0.4-0.1-0.1-0.3
Incentive salience index mean0.10.20.50.5-0.4-0.3-0.4-0.20.5-0.20.70.30.50.1
Condit. Reinf. lever presses0.30.41.4-1.11.20.30.70.9-0.30.4-0.2-0.40.10.2
Condit. Reinf. active minus inactive responses0.60.81.7-0.10.11.30.70.3-1.21.0-0.7-1.00.9-1.3
Condit. Reinf. active-inactive response ratio0.50.51.5-0.80.51.20.70.6-1.10.7-0.5-0.7-0.1-0.5
Condit. Reinf. active responses0.81.13.21.8-1.4-0.0-0.6-1.00.00.10.1-0.11.7-1.5
Condit. Reinf. inactive responses1.62.05.92.4-1.9-1.3-1.3-1.41.1-0.40.70.52.0-0.9
Condit. Reinf. lever presses0.20.31.50.5-0.70.7-0.10.1-0.20.60.2-0.51.2-0.6
Condit. Reinf. lever reinforcers received0.81.13.51.9-1.50.1-0.7-1.20.0-0.00.30.01.5-1.3
Conditioned reinforcement - actives0.00.10.20.2-0.30.3-0.30.00.20.20.3-0.20.40.1
Conditioned reinforcement - inactives0.10.10.3-0.50.30.40.30.6-0.10.2-0.1-0.20.20.2
Conditioned locomotion0.20.30.7-0.80.50.80.40.6-0.30.50.3-0.3-0.10.3
Patch foraging indifference point 0 sec0.40.72.40.30.10.70.50.2-0.60.9-0.8-0.91.6-1.3
Patch foraging indifference point AUC0.10.10.80.1-0.40.90.0-0.1-0.50.1-0.2-0.1-0.3-0.3
Delay disc. indifference point, 0s delay0.10.10.40.20.2-0.6-0.0-0.30.4-0.3-0.30.1-0.10.1
Delay disc. indifference point, 16s delay0.30.41.30.70.4-0.60.1-1.1-0.2-0.8-0.70.2-0.2-0.9
Delay disc. indifference point, 2s delay0.30.30.8-0.20.70.50.70.0-0.80.5-0.5-0.70.2-0.9
Delay disc. indifference point, 24s delay0.30.31.20.60.2-0.5-0.1-1.10.0-0.6-0.60.7-0.6-0.4
Delay disc. indifference point, 4s delay3.43.66.4-1.92.51.92.41.4-2.51.6-2.2-1.50.3-1.6
Delay disc. indifference point, 8s delay1.11.32.91.1-0.6-0.9-0.9-1.70.7-1.60.61.5-1.40.4
Indifference point function ln k0.20.40.9-0.80.80.30.81.0-0.50.7-0.3-0.70.6-0.2
Indifference point function log k0.20.40.9-0.80.80.30.81.0-0.50.7-0.3-0.70.6-0.2
Patch foraging total patch changes 0 sec0.61.13.2-0.00.31.00.80.6-0.81.2-1.0-1.21.8-1.4
Patch foraging total patch changes 12 sec1.62.15.7-1.00.92.41.31.0-1.81.5-1.5-1.50.6-1.3
Patch foraging total patch changes 18 sec1.82.85.4-0.40.92.01.50.9-2.11.8-1.9-1.81.7-2.3
Patch foraging total patch changes 24 sec0.40.71.9-0.60.61.40.80.7-1.10.9-0.6-0.90.3-0.7
Patch foraging total patch changes 6 sec0.30.41.60.6-0.20.90.3-0.4-0.80.5-0.5-0.50.4-1.3
Patch foraging time to switch 0 sec0.10.30.80.20.3-0.6-0.2-0.70.4-0.60.30.5-0.90.4
Patch foraging water rate 0 sec0.00.10.2-0.2-0.30.4-0.00.3-0.2-0.0-0.10.0-0.40.2
Patch foraging water rate 12 sec0.00.10.2-0.4-0.00.40.20.4-0.40.2-0.3-0.1-0.30.1
Patch foraging water rate 18 sec0.30.51.5-0.70.31.00.50.4-1.00.3-0.8-0.4-1.2-0.1
Patch foraging water rate 24 sec0.10.10.70.4-0.8-0.1-0.5-0.30.1-0.2-0.00.3-0.50.2
Patch foraging water rate 6 sec0.20.30.9-0.50.00.40.40.7-0.50.6-1.0-0.50.0-0.2
Seeking ratio, delayed vs. immediate footshock0.50.62.0-0.50.11.40.50.7-1.01.10.1-0.60.7-0.6
Distance traveled before self-admin0.10.20.3-0.50.50.50.50.4-0.40.5-0.5-0.40.3-0.2
Distance traveled after self-admin1.01.22.1-1.31.41.21.41.0-1.40.4-1.5-0.4-0.5-0.6
Extensor digitorum longus weight0.20.85.41.0-0.8-0.5-0.5-0.10.60.60.5-0.52.3-0.6
Bone: elastic displacement0.10.10.40.20.1-0.50.1-0.20.0-0.1-0.70.10.2-0.4
Bone: elastic work0.20.30.70.80.2-0.80.0-0.70.2-0.1-0.60.10.7-0.9
Bone: endosteal estimation0.10.20.7-0.80.50.10.30.5-0.20.00.20.0-0.70.5
Bone: endosteal perimeter0.40.82.3-1.51.40.71.11.0-0.90.5-0.3-0.5-0.50.1
Epididymis fat weight1.03.37.20.8-2.5-1.5-2.2-0.32.4-1.51.81.7-0.92.7
Delta time in closed arm before/after self-admin1.21.12.3-0.20.71.11.00.3-1.21.0-1.4-1.40.8-1.5
Delta time in open arm before/after self-admin0.40.40.60.5-0.8-0.4-0.8-0.40.7-0.50.70.6-0.20.7
Diff in mean of infusions in LGA sessions0.40.51.2-0.71.00.40.70.0-0.80.2-0.6-0.7-1.1-0.2
Delay discount exponential model param0.40.40.9-0.2-0.8-0.1-0.50.90.70.30.9-0.20.61.0
Extinction: sum of active levers before priming2.83.14.5-2.12.01.92.11.7-2.01.6-2.1-1.6-0.0-0.9
Active lever presses in extinction session 60.30.30.9-0.0-0.30.90.3-0.1-0.90.4-0.8-0.4-0.6-0.6
Bone: final force0.00.10.4-0.10.1-0.1-0.10.00.2-0.10.60.10.10.3
Bone: final moment0.00.10.5-0.00.0-0.2-0.2-0.10.2-0.20.70.2-0.10.4
Food consumed during 24 hour testing period0.30.41.5-0.50.51.20.60.1-1.20.2-0.3-0.2-0.8-0.5
Glucose2.84.46.61.8-2.2-2.5-2.4-1.82.6-2.02.22.1-1.12.0
Heart weight0.81.34.8-1.80.11.50.42.2-0.20.90.3-0.60.11.4
Delay discount hyperbolic model param0.40.40.90.0-0.9-0.1-0.60.60.80.21.0-0.10.60.9
Intermittent access intake day 1-15 change0.40.81.9-1.20.80.70.91.4-0.70.9-0.4-1.00.8-0.2
Intermittent access intake escalation0.61.32.8-1.41.11.11.21.7-1.11.2-0.7-1.30.9-0.4
Intermittent access intake escalation 20.10.10.4-0.3-0.0-0.4-0.20.40.4-0.40.40.2-0.10.6
Intermitt. access day 1 inactive lever presses0.31.13.7-1.50.70.50.81.9-0.41.0-1.1-1.00.80.3
Intermitt. access day 15 inactive lever presses0.10.20.8-0.90.50.50.30.9-0.10.30.2-0.30.10.5
Intermitt. access escalation Index0.30.41.70.50.60.30.4-0.7-0.70.2-0.4-0.40.4-1.3
Intermittent access day 1 total infusions0.10.20.4-0.50.50.30.10.10.10.30.3-0.0-0.60.6
Intermittent access day 15 total infusions0.50.71.8-1.31.00.80.81.3-0.41.0-0.2-0.90.30.3
Intermittent access terminal intake (last 3 days)0.10.10.2-0.50.40.10.20.50.10.4-0.2-0.40.20.3
Intermittent access total infusions0.20.21.0-0.60.3-0.0-0.10.50.50.20.5-0.1-0.31.0
Intermittent access day 1 locomotion0.81.02.5-1.61.40.91.01.3-0.51.3-0.6-0.90.10.3
Intermittent access day 15 total locomotion0.71.33.3-1.81.21.11.01.8-0.51.4-0.1-1.10.40.5
Intermittent access total locomotion1.01.22.9-1.71.41.11.11.5-0.71.4-0.3-1.00.10.3
Intermittent access standard deviation0.30.61.20.8-0.9-0.9-0.9-0.70.9-0.61.10.7-0.10.6
Left kidney weight0.10.62.00.2-1.2-0.5-0.70.81.00.30.5-0.21.40.7
Right kidney weight0.10.63.60.0-0.70.40.01.00.00.8-0.4-0.81.9-0.4
Cocaine induced anxiety1.62.23.21.4-1.4-1.5-1.7-1.51.8-1.71.51.6-0.81.2
Post-drug Anxiety0.40.51.30.0-0.3-0.8-0.6-0.11.0-0.70.80.7-0.61.2
Baseline Anxiety1.41.62.4-1.41.31.11.41.5-1.41.4-1.1-1.40.9-0.9
Tail length0.00.20.40.4-0.1-0.7-0.0-0.20.20.1-0.6-0.20.6-0.5
Length with tail0.10.62.90.3-0.2-0.00.30.4-0.40.8-0.9-0.81.7-1.2
Length without tail0.41.43.6-0.30.21.00.91.1-1.11.4-1.1-1.41.9-1.5
Times rat made contact with spout2.32.66.8-2.62.41.41.71.4-1.60.6-0.9-0.7-2.10.5
Lifetime Intake0.20.30.6-0.70.30.30.10.80.30.70.4-0.40.20.7
Liver weight, left1.52.46.02.4-1.9-1.8-1.7-2.01.6-1.40.81.30.6-0.1
Liver weight, right0.10.10.3-0.3-0.10.5-0.00.60.20.3-0.1-0.30.40.3
Locomotor activity0.00.10.2-0.40.5-0.20.20.20.00.10.10.0-0.30.3
Locomotor testing distance0.61.12.2-1.51.50.71.21.4-0.81.1-0.8-1.10.4-0.2
Locomotor testing rearing1.12.24.5-1.51.52.11.61.5-1.61.7-1.1-1.70.7-0.9
Locomotion in novel chamber0.00.00.1-0.2-0.0-0.0-0.00.30.10.10.3-0.00.30.2
Locomotion in novel chamber post-restriction0.40.72.0-1.10.60.60.91.4-0.70.5-1.2-0.60.5-0.2
Fecal boli incidents, locomotor time 10.10.10.40.3-0.60.1-0.4-0.30.20.00.20.3-0.60.4
Change in fecal boli incidents, locomotor task0.30.31.1-0.40.4-1.1-0.00.20.6-0.70.20.6-0.40.8
Time >=10cm from walls, locomotor time 10.60.61.50.4-0.3-1.1-0.6-0.70.8-1.1-0.00.7-1.20.8
Bouts of movement, locomotor time 10.50.52.10.70.00.20.3-0.3-0.40.2-1.0-0.61.2-1.5
Total resting periods, locomotor time 10.40.51.90.60.00.20.3-0.3-0.40.3-0.8-0.61.2-1.4
Rest time, locomotor task time 10.10.10.4-0.00.0-0.3-0.10.10.30.20.7-0.2-0.10.3
Distance moved, locomotor task time 10.30.41.20.5-0.3-1.1-0.5-0.70.6-1.0-0.00.8-0.40.3
Vertical activity count, locomotor time 10.30.82.9-0.10.60.30.80.3-0.80.4-1.7-0.61.1-1.3
Time >=10cm from walls, locomotor time 20.10.10.3-0.50.3-0.40.20.60.1-0.0-0.30.0-0.10.3
Bouts of movement, locomotor time 20.20.41.6-0.90.20.50.20.6-0.10.1-0.0-0.1-1.30.9
Total resting periods, locomotor time 20.20.41.4-1.10.30.50.30.8-0.20.2-0.0-0.3-1.20.9
Rest time, locomotor task time 20.30.40.90.3-0.3-1.0-0.5-0.50.7-0.80.40.7-0.80.6
Distance moved, locomotor task time 20.10.20.90.4-0.2-0.5-0.1-0.10.10.0-0.4-0.00.9-0.5
Vertical activity count, locomotor time 20.40.51.3-0.30.50.40.60.6-0.50.7-1.0-0.71.2-0.8
Light reinforcement 12.46.018.60.02.42.12.5-0.4-3.21.8-3.0-2.21.5-4.3
Light reinforcement 22.94.47.5-1.22.42.42.40.8-2.72.0-2.2-2.20.9-2.6
Bone: marrow area0.10.20.7-0.80.50.10.30.5-0.20.00.30.0-0.70.5
Bone: maximum diameter1.01.83.3-1.71.51.11.61.8-1.31.3-1.3-1.30.9-0.7
Bone: maximum force0.10.21.00.20.20.30.20.0-0.30.4-0.2-0.41.0-0.8
Bone: maximum moment0.10.10.50.30.10.10.1-0.2-0.30.2-0.0-0.20.7-0.6
Mean time between licks in bursts0.20.51.50.4-0.30.50.30.1-0.60.5-0.8-0.61.2-1.2
Mean num. licks in bursts0.50.83.6-1.21.40.50.90.1-1.1-0.1-0.4-0.0-1.90.1
Cd content in liver0.10.10.40.1-0.40.7-0.3-0.2-0.2-0.10.20.1-0.50.2
Co content in liver0.20.20.80.20.30.50.2-0.7-0.5-0.2-0.50.0-0.9-0.4
Cu content in liver0.10.10.60.4-0.4-0.6-0.3-0.00.50.1-0.3-0.10.7-0.1
Fe content in liver0.70.92.50.10.50.40.80.1-1.00.9-1.3-1.01.1-1.6
K content in liver0.30.30.8-0.40.9-0.30.60.4-0.10.5-0.8-0.60.7-0.4
Mg content in liver0.50.51.6-0.81.3-0.10.80.7-0.20.6-0.8-0.70.7-0.3
Mn content in liver0.00.00.1-0.10.40.20.2-0.1-0.1-0.10.10.1-0.2-0.1
Na content in liver3.63.87.1-2.02.70.42.32.3-1.32.0-2.1-2.02.2-1.4
Rb content in liver0.00.00.20.0-0.10.10.10.3-0.10.3-0.1-0.20.5-0.2
Se content in liver0.70.91.8-0.71.00.31.00.9-0.71.0-1.3-1.11.0-0.9
Sr content in liver0.50.41.40.60.5-0.40.3-1.2-0.5-0.2-0.7-0.1-0.5-1.1
Zn content in liver0.20.20.7-0.20.30.50.40.4-0.30.5-0.8-0.60.5-0.5
Bone: minimum diameter0.20.31.5-0.2-0.00.3-0.2-0.2-0.1-0.60.50.6-1.20.6
Time in familiar zone, hab. session 10.20.20.60.3-0.8-0.1-0.6-0.20.3-0.50.60.5-0.40.5
Time in novel zone, hab. session 10.00.00.00.1-0.00.10.0-0.2-0.00.0-0.2-0.00.1-0.2
Total zone transitions, hab. session 15.57.712.4-1.82.82.13.12.2-2.93.0-3.5-3.12.5-3.1
Total locomotion distance, hab. session 14.96.911.8-1.82.72.12.92.1-2.72.8-3.4-3.02.2-2.8
Locomotion velocity, hab. session 14.97.010.6-1.92.82.12.92.2-2.62.9-3.3-3.12.3-2.7
Time in familiar zone, hab. session 20.30.41.10.1-0.60.6-0.5-0.4-0.1-0.50.90.6-1.00.5
Time in novel zone, hab. session 20.20.21.10.3-0.1-1.0-0.2-0.10.6-0.2-0.40.10.40.1
Total zone transitions, hab. session 21.11.43.3-0.61.10.51.11.0-0.71.3-1.4-1.51.8-1.3
Total locomotion distance, hab. session 21.41.93.4-0.71.11.31.41.0-1.31.5-1.9-1.71.4-1.5
Locomotion velocity, hab. session 21.21.73.4-0.71.11.11.30.9-1.21.4-1.8-1.61.2-1.4
Novel to familiar place preference ratio1.01.14.10.00.60.10.80.6-0.51.1-1.3-1.12.0-1.5
Novelty place preference1.21.34.3-0.00.60.20.90.7-0.71.2-1.6-1.22.1-1.6
Time in novel zone, NPP test1.21.33.8-0.20.80.31.00.8-0.71.2-1.6-1.31.9-1.5
Total zone transitions, NPP test1.31.94.7-0.31.10.61.30.8-1.01.4-1.8-1.62.2-1.8
Total locomotion distance, NPP test1.31.84.1-0.81.50.71.50.9-1.11.4-2.0-1.61.3-1.5
Locomotion velocity, NPP test1.42.03.5-0.71.40.71.51.0-1.21.6-1.9-1.71.7-1.6
Intraocular pressure1.42.03.71.5-1.9-0.5-1.7-1.61.0-1.51.31.5-1.40.9
Delta distance traveled before/after self-admin1.31.43.0-1.71.61.21.41.2-1.50.4-1.0-0.5-1.0-0.2
Delta ambulatory time before/after self-admin1.11.42.9-1.41.61.21.50.9-1.70.5-1.3-0.7-0.6-0.8
Parametrial fat weight1.33.16.60.6-1.8-1.8-1.9-0.52.2-1.81.92.0-1.32.6
Pavlov. Cond. lever latency1.72.14.72.2-1.9-1.3-1.6-2.11.1-1.40.91.3-0.50.0
Pavlov. Cond. magazine entry latency0.81.02.6-1.61.11.41.01.5-0.80.7-0.3-0.70.00.3
Pavlov. Cond. change in total contacts3.03.28.1-2.21.72.81.82.1-2.01.7-1.1-1.70.4-0.6
Pavlov. Cond. index score1.82.25.2-2.31.91.91.62.1-1.31.3-0.7-1.30.20.0
Pavlov. Cond. latency score1.51.94.9-2.21.81.61.52.0-1.11.2-0.6-1.10.00.2
Pavlov. Cond. lever contacts2.02.45.7-2.42.11.51.72.2-1.21.4-0.9-1.40.20.1
Pavlov. Cond. magazine entry number0.50.72.01.4-0.9-1.3-0.7-1.20.6-0.5-0.20.40.3-0.5
Pavlov. Cond. intertrial magazine entries0.30.31.10.8-0.1-1.1-0.2-0.60.3-0.1-0.10.20.8-0.6
Pavlov. Cond. lever-magazine prob. diff.1.82.25.0-2.21.81.81.62.1-1.31.3-0.6-1.30.4-0.0
Pavlov. Cond. response bias1.72.15.4-2.31.81.71.52.2-1.11.2-0.5-1.20.10.3
Pavlov. Cond. lever latency0.30.41.00.4-0.2-1.0-0.5-0.70.6-0.80.30.7-0.60.4
Pavlov. Cond. magazine entry latency2.12.55.9-1.11.12.41.61.4-2.01.8-1.2-1.71.1-1.5
Pavlov. Cond. change in total contacts0.81.22.7-0.20.11.60.80.7-1.41.4-0.4-1.21.5-1.5
Pavlov. Cond. index score1.72.34.9-1.31.02.21.41.6-1.81.9-1.0-1.71.1-1.2
Pavlov. Cond. latency score2.12.85.7-1.41.22.41.71.7-2.02.0-1.2-1.91.2-1.4
Pavlov. Cond. lever contacts0.40.51.0-0.70.41.00.60.9-0.70.9-0.3-0.80.6-0.3
Pavlov. Cond. magazine entry number1.92.45.81.4-1.1-2.4-1.5-1.61.9-1.80.91.7-1.01.1
Pavlov. Cond. intertrial magazine entries1.72.65.22.0-1.6-2.3-1.7-1.91.9-1.70.91.6-0.30.6
Pavlov. Cond. lever-magazine prob. diff.2.02.75.7-1.51.22.41.61.8-1.92.0-1.1-1.81.1-1.1
Pavlov. Cond. response bias0.40.51.4-0.60.21.20.50.9-0.71.0-0.0-0.80.7-0.3
Time in closed arm before self-admin1.31.72.80.7-1.0-1.1-1.3-1.01.3-1.31.71.7-1.41.5
Time in closed arm after self-admin0.20.31.50.4-0.1-0.3-0.3-0.80.1-0.5-0.00.3-1.20.1
Time in open arm before self-admin1.71.84.2-1.41.40.91.32.0-0.81.4-0.4-1.52.0-0.6
Time in open arm after self-admin0.50.63.2-0.00.20.50.40.6-0.50.9-0.0-0.71.8-0.9
Bone: periosteal estimation0.20.31.1-1.00.80.20.61.0-0.40.5-0.0-0.30.30.2
Bone: periosteal perimeter0.20.31.0-0.71.00.00.80.5-0.60.3-0.7-0.30.1-0.4
Bone: post-yield work0.00.10.2-0.00.00.20.10.2-0.30.2-0.0-0.20.5-0.3
Progressive ratio test 1 active lever presses0.70.92.4-0.40.50.80.70.9-0.51.4-0.8-1.31.6-0.8
Progressive ratio test 1 breakpoint0.60.82.1-0.40.40.80.60.9-0.41.3-0.7-1.21.4-0.6
Progressive ratio test 1 inactive lever presses0.20.20.5-0.50.50.40.50.6-0.30.6-0.7-0.50.3-0.2
Progressive ratio test 2 active lever presses0.10.10.20.30.0-0.4-0.0-0.30.30.1-0.4-0.20.3-0.2
Progressive ratio test 2 breakpoint0.10.10.20.4-0.1-0.4-0.1-0.30.4-0.0-0.3-0.10.3-0.1
Progressive ratio test 2 inactive lever presses0.60.92.01.0-1.1-1.2-1.1-0.71.4-0.61.10.60.30.8
Incentive Sensitization - Responses0.91.32.61.1-1.0-1.6-1.2-1.11.4-1.30.91.0-0.40.8
Incentive Sensitization - Breakpoint1.01.32.41.1-1.0-1.6-1.2-1.21.3-1.40.91.1-0.50.8
Sum of active levers in priming session hrs 5-60.50.51.2-1.11.00.30.80.7-0.50.2-1.0-0.1-0.70.2
Progressive ratio0.40.61.4-1.21.10.70.80.6-0.60.4-0.7-0.3-0.90.2
Food seeking constrained by brief footshock0.70.92.6-1.61.01.20.81.0-0.90.4-0.0-0.5-1.20.6
Seeking ratio, punishment vs. effort0.10.10.40.5-0.6-0.0-0.4-0.30.1-0.30.6-0.10.1-0.1
Retroperitoneal fat weight4.519.029.44.9-5.4-4.9-5.0-4.44.9-4.53.84.5-1.42.7
Reaction time number correct0.30.61.81.2-0.4-0.6-0.1-0.8-0.10.1-0.6-0.21.3-1.3
Reaction time mean minus median0.40.93.20.2-1.0-0.6-1.10.21.2-0.51.80.70.31.4
Reaction time mean minus median AUC0.10.20.7-0.2-0.30.2-0.10.60.00.30.8-0.10.60.3
Reaction time num false alarms0.00.00.1-0.00.20.10.0-0.2-0.1-0.10.0-0.0-0.3-0.0
Reaction time num false alarms AUC0.10.10.3-0.20.50.30.40.1-0.40.4-0.4-0.50.2-0.4
Reaction time trials correct on left0.30.61.81.2-0.4-0.6-0.1-0.8-0.10.1-0.6-0.21.3-1.3
Reaction time trials on left0.30.61.61.2-0.5-0.6-0.2-0.8-0.00.1-0.5-0.11.3-1.2
Reaction time mean0.50.92.00.0-0.7-0.2-0.8-0.30.7-1.11.31.0-1.41.4
Reaction time mean AUC0.30.61.3-0.0-0.5-0.2-0.6-0.30.5-0.91.00.9-1.11.1
Median of all reaction times0.60.83.00.0-0.5-0.1-0.7-0.50.5-1.11.01.1-1.71.2
Reaction time omissions1.01.54.20.2-1.1-0.7-1.3-0.21.5-1.11.71.3-0.92.0
Reaction time false alarm rate0.10.10.5-0.60.60.40.30.2-0.20.1-0.1-0.1-0.70.3
Reaction time premature initiation rate0.10.10.5-0.2-0.1-0.1-0.30.40.60.10.60.00.20.7
Reaction time premature initiations0.10.20.80.4-0.4-0.5-0.4-0.00.60.10.4-0.10.90.1
Std. dev. reaction times0.30.62.2-0.0-0.7-0.1-0.80.10.8-0.61.50.7-0.41.3
Reaction time trials completed0.30.61.61.2-0.5-0.6-0.2-0.8-0.00.1-0.5-0.11.3-1.2
Reaction time trials AUC0.30.61.81.2-0.6-0.6-0.3-0.7-0.00.1-0.4-0.21.3-1.2
Run reversals in cocaine runway, females0.40.41.41.1-0.40.1-0.2-1.1-0.30.1-0.30.20.4-1.2
Run reversals in cocaine runway, males1.71.73.1-1.61.51.11.51.8-1.31.3-1.2-1.40.8-0.7
Latency to leave start box in cocaine runway0.10.10.3-0.00.0-0.6-0.10.10.4-0.30.10.5-0.00.3
Latency to leave start box in cocaine runway, F0.20.30.7-0.0-0.4-0.8-0.40.10.7-0.60.30.7-0.40.8
Latency to leave start box in cocaine runway, M0.20.20.6-0.10.70.50.60.1-0.50.3-0.5-0.00.4-0.7
Std. dev. time between licks in bursts0.60.82.31.5-0.9-0.8-0.7-1.50.4-0.9-0.20.70.0-0.7
Total sessions with >9 infusions0.60.81.8-1.40.91.10.61.3-0.31.30.2-0.80.20.6
Short access day 1 total inactive lever presses0.60.72.5-0.50.90.10.70.8-0.41.2-0.3-1.01.6-0.7
Short access day 10 total inactive lever presses0.10.20.7-0.20.00.20.30.6-0.30.2-0.7-0.40.8-0.4
Short access day 1 total infusions0.20.30.7-0.60.70.60.30.6-0.10.80.3-0.60.20.2
Short access day 10 total infusions0.20.21.0-0.30.10.0-0.3-0.10.6-0.10.30.3-0.91.0
Short access total infusions0.30.30.9-0.70.50.50.20.80.20.90.4-0.50.50.6
Short access day 1 locomotion2.83.57.6-2.32.22.81.92.0-2.02.2-0.7-1.90.3-0.6
Short access day 10 total locomotion0.81.64.1-2.01.41.41.11.9-0.91.5-0.2-1.00.10.5
Short access total locomotion2.02.45.1-2.31.81.91.52.1-1.22.0-0.5-1.50.40.1
One hour access (0.3 mA shock)0.10.10.20.5-0.4-0.1-0.3-0.30.30.00.1-0.10.3-0.1
Compulsive drug intake1.01.13.70.30.50.30.90.1-0.90.9-1.6-1.01.6-1.9
One hour access (shock baseline)0.20.31.2-0.70.10.2-0.20.60.40.10.7-0.0-0.41.1
Social response proportion0.10.10.80.0-0.30.90.10.0-0.60.1-0.3-0.10.0-0.4
Social responses0.60.82.20.20.30.90.60.0-1.10.8-1.1-0.91.1-1.5
Social time0.20.21.00.2-0.60.7-0.10.4-0.20.50.2-0.31.0-0.3
Soleus weight0.61.82.7-1.51.60.81.51.6-1.11.4-1.3-1.51.1-0.8
Bone: stiffness0.20.41.2-0.10.00.90.30.5-0.50.7-0.1-0.71.1-0.6
Tibialis anterior weight0.20.83.21.2-0.7-1.4-0.7-0.50.90.10.4-0.01.8-0.4
Time to tail flick, vehicle, before self-admin2.72.86.62.0-2.6-1.4-2.0-1.61.5-1.71.31.9-0.50.8
Time to tail flick, vehicle, after self-admin5.87.610.22.9-2.8-2.7-3.1-3.23.0-3.02.82.8-1.91.9
Time to tail flick, test, before self-admin1.71.82.91.1-1.4-1.0-1.4-1.31.0-1.71.61.4-1.41.1
Time to tail flick, test, after self-admin1.31.32.11.2-1.0-1.2-1.2-1.41.0-1.11.41.4-0.70.6
Delta time to tail flick, vehicle, before/after SA0.60.61.00.4-0.1-0.8-0.7-0.80.9-0.81.00.5-0.90.8
Delta time to tail flick, test, before/after SA0.60.62.30.30.50.30.6-0.1-0.80.9-0.6-0.51.3-1.5
Tibia length0.41.24.00.80.3-0.50.6-0.1-0.30.7-1.8-0.92.0-1.9
Ambulatory time before self-admin0.00.10.2-0.40.20.40.00.20.10.10.10.1-0.40.4
Ambulatory time after self-admin1.31.52.8-1.31.61.61.50.7-1.70.4-1.6-0.5-1.0-0.8
Bone: tissue strength1.41.53.21.8-1.4-1.4-1.3-1.61.2-1.00.91.10.10.1
Total heroin consumption3.44.08.32.7-2.0-2.2-2.1-2.91.8-2.31.11.9-1.10.5
Bone: trabecular number0.10.10.3-0.60.60.20.40.5-0.30.30.6-0.10.10.1
Bone: trabecular spacing0.20.31.10.5-0.20.30.1-0.3-0.20.4-1.1-0.60.6-0.9
Bone: trabecular thickness0.30.41.2-1.10.80.30.30.6-0.0-0.20.50.3-0.80.9
Bone: trabecular tissue density1.01.53.0-1.20.61.71.01.7-1.11.5-0.3-1.11.5-0.6
Water consumed over 24 hours0.60.93.6-1.30.81.40.60.5-1.0-0.10.10.1-1.90.6
Number of responses in last shaping day3.94.25.6-1.82.02.32.21.9-2.22.3-2.3-2.41.2-1.7