Hub : Genes

LOC134479334

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability LOC134479334 0.04 0.03 2.8e-03 0.03 0.02 0.03 0.03 7.3e-04 3.2e-03 1.2e-03 1.4e-03
2 Liver gene expression LOC134479334 0.06 0.04 9.0e-05 0.03 0.03 0.02 0.02 1.6e-04 5.8e-04 4.9e-03 1.1e-03
3 LHb gene expression LOC134479334 0.52 0.17 1.7e-09 0.41 0.23 0.34 0.38 1.0e-10 2.7e-06 8.6e-09 6.5e-10
4 IC gene expression LOC134479334 0.33 0.09 3.3e-16 0.34 0.32 0.27 0.32 3.1e-15 4.3e-14 8.3e-12 2.8e-14
5 OFC mRNA stability LOC134479334 0.6 0.18 2.3e-07 0.2 0.22 0.21 0.2 1.5e-05 7.8e-06 1.3e-05 1.7e-05
6 RMTg mRNA stability LOC134479334 0.17 0.09 2.1e-03 0.06 0.07 0.05 0.05 8.2e-03 5.6e-03 1.8e-02 2.1e-02
7 pVTA mRNA stability LOC134479334 0.08 0.05 1.7e-05 0.06 0.06 0.07 0.07 5.8e-06 8.7e-06 4.0e-06 3.1e-06
8 PL gene expression LOC134479334 0.14 0.04 0.0e+00 0.24 0.26 0.26 0.25 1.3e-25 1.1e-27 9.3e-28 4.6e-27
9 IC mRNA stability LOC134479334 0.11 0.07 1.8e-03 0.07 0.04 0.03 0.06 8.6e-04 1.0e-02 2.1e-02 2.0e-03
10 pVTA gene expression LOC134479334 0.22 0.06 0.0e+00 0.33 0.34 0.34 0.35 1.5e-27 1.3e-28 2.2e-28 7.4e-29
11 NAcc mRNA stability LOC134479334 0.09 0.05 9.6e-12 0.09 0.08 0.07 0.09 1.2e-13 7.2e-12 2.2e-11 7.1e-13
12 Brain gene expression LOC134479334 0.24 0.08 0.0e+00 0.3 0.3 0.3 0.3 7.1e-29 1.0e-28 2.0e-28 9.4e-29
13 BLA gene expression LOC134479334 0.23 0.08 3.6e-14 0.25 0.24 0.26 0.28 1.5e-13 3.9e-13 5.4e-14 4.6e-15
14 PL mRNA stability LOC134479334 0.08 0.04 2.4e-09 0.08 0.1 0.1 0.09 3.6e-09 1.1e-10 1.4e-10 6.4e-10
15 OFC gene expression LOC134479334 0.55 0.14 6.0e-10 0.24 0.26 0.26 0.25 1.6e-06 7.5e-07 8.1e-07 1.2e-06
16 NAcc gene expression LOC134479334 0.18 0.05 0.0e+00 0.35 0.36 0.36 0.36 2.5e-55 2.6e-56 3.1e-56 3.5e-56
17 LHb mRNA stability LOC134479334 0.25 0.12 1.1e-06 0.31 0.24 0.27 0.28 3.8e-08 1.8e-06 4.3e-07 2.0e-07
18 RMTg gene expression LOC134479334 0.19 0.11 8.7e-04 0.13 0.1 0.06 0.08 2.4e-04 1.3e-03 1.4e-02 4.3e-03
19 BLA mRNA stability LOC134479334 0.12 0.07 5.9e-05 0.1 0.08 0.08 0.09 6.4e-06 3.4e-05 3.3e-05 1.9e-05
20 IL gene expression LOC134479334 0.31 0.13 1.4e-06 0.26 0.22 0.25 0.25 6.6e-07 4.1e-06 1.2e-06 1.1e-06
21 IL mRNA stability LOC134479334 0.14 0.09 7.0e-03 0.1 0.07 0.04 0.06 2.7e-03 1.1e-02 4.5e-02 1.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density4.17.09.4-2.1-2.2-2.2-2.5-2.8-3.1-2.5-2.9-2.5-2.2-2.8-2.7-2.8-2.9-2.8-2.7-2.9-2.7-2.7-2.9-2.9
Area under the delay curve0.10.10.30.30.30.30.30.30.20.30.30.40.60.30.30.40.30.40.40.50.10.10.40.4
BMI with tail0.10.20.70.90.70.70.60.70.50.40.40.40.40.30.50.50.30.30.20.10.30.30.10.1
BMI without tail0.10.30.6-0.2-0.3-0.3-0.3-0.1-0.3-0.5-0.5-0.4-0.5-0.7-0.3-0.3-0.7-0.6-0.6-0.7-0.6-0.6-0.8-0.8
Body weight0.52.04.52.12.12.11.81.61.41.61.21.41.51.21.31.21.11.11.10.90.90.90.90.9
Weight adjusted by age0.00.10.2-0.1-0.1-0.10.1-0.3-0.10.0-0.1-0.2-0.1-0.1-0.3-0.3-0.3-0.3-0.2-0.3-0.5-0.4-0.4-0.4
Bone surface0.71.42.3-0.7-0.8-0.8-1.0-1.2-1.5-1.0-1.4-1.2-0.8-1.2-1.3-1.3-1.4-1.3-1.3-1.1-1.1-1.1-1.2-1.2
Bone volume1.52.74.2-1.3-1.3-1.3-1.4-1.8-2.1-1.4-1.9-1.6-1.1-1.8-1.8-1.8-1.9-1.8-1.7-1.7-1.7-1.6-1.7-1.7
Breakpoint value in progressive ratio session0.60.71.4-0.9-0.9-0.9-0.9-1.0-1.2-0.8-0.9-0.8-0.4-0.8-0.8-0.8-0.8-0.8-0.8-0.9-1.1-1.1-0.6-0.6
Number of licking bursts0.61.01.41.21.01.01.01.21.11.01.11.00.81.11.01.01.00.91.00.80.80.70.90.9
Context. condit. distance diff. score2.53.13.6-1.6-1.7-1.7-1.7-1.7-1.8-1.7-1.8-1.6-1.7-1.8-1.7-1.7-1.8-1.8-1.8-1.9-1.7-1.8-1.9-1.9
Locomotion velocity, session 10.10.10.3-0.2-0.1-0.1-0.10.30.20.00.20.2-0.00.20.30.30.20.20.10.50.30.40.50.5
Locomotion distance, session 10.10.10.7-0.8-0.6-0.6-0.6-0.4-0.3-0.4-0.2-0.4-0.4-0.1-0.2-0.2-0.1-0.2-0.20.0-0.1-0.10.00.0
Locomotion velocity, session 20.10.10.3-0.2-0.1-0.1-0.00.50.4-0.00.30.3-0.10.20.40.30.10.30.30.20.10.10.20.2
Locomotion distance, session 20.10.20.30.30.40.40.40.40.30.40.40.50.50.40.50.50.50.50.50.50.30.40.50.5
Locomotion velocity, session 30.40.40.7-0.9-0.8-0.8-0.7-0.6-0.5-0.6-0.6-0.5-0.8-0.7-0.5-0.5-0.6-0.6-0.5-0.8-0.7-0.7-0.8-0.8
Locomotion distance, session 30.60.71.1-1.1-1.0-1.0-0.7-0.9-0.8-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.8-1.0-0.7-0.7-1.0-1.0
Stereotopy head waving bouts, day 32.22.64.6-2.1-2.1-2.1-2.0-1.6-1.7-1.8-1.5-1.7-1.7-1.3-1.7-1.6-1.6-1.5-1.5-1.1-1.3-1.3-1.1-1.1
Stereotopy head waving duration, day 30.20.30.6-0.7-0.8-0.8-0.8-0.4-0.5-0.6-0.4-0.6-0.6-0.3-0.6-0.5-0.5-0.5-0.5-0.0-0.3-0.3-0.1-0.1
Locomotion velocity, session 70.10.10.2-0.3-0.3-0.3-0.4-0.2-0.4-0.3-0.4-0.4-0.1-0.4-0.4-0.4-0.4-0.3-0.3-0.1-0.2-0.1-0.1-0.1
Locomotion distance, session 70.10.10.2-0.4-0.4-0.4-0.3-0.1-0.2-0.3-0.3-0.2-0.3-0.5-0.2-0.2-0.3-0.2-0.2-0.2-0.3-0.3-0.2-0.2
Stereotopy head waving bouts, day 70.10.20.60.40.30.30.30.30.30.30.50.40.30.80.30.30.40.30.30.40.50.50.40.4
Stereotopy head waving duration, day 70.00.00.30.20.10.10.10.00.20.10.30.2-0.00.50.10.10.20.10.10.10.20.20.10.1
Locomotion velocity, session 81.82.13.2-1.7-1.7-1.7-1.8-1.2-1.4-1.7-1.4-1.3-1.6-1.3-1.3-1.4-1.5-1.4-1.3-1.3-1.3-1.3-1.2-1.2
Locomotion distance, session 81.92.73.1-1.7-1.7-1.7-1.7-1.5-1.7-1.7-1.7-1.5-1.6-1.8-1.5-1.5-1.7-1.6-1.5-1.7-1.7-1.7-1.7-1.7
Degree of sensitization distance0.30.30.60.60.60.60.40.80.60.40.50.60.40.40.50.50.50.50.50.70.40.50.70.7
Degree of sensitization stereotypy1.71.82.71.51.51.51.41.21.31.41.51.41.31.61.31.31.41.31.21.21.31.31.21.2
Conditioned locomotion3.64.25.1-1.7-1.9-1.9-2.1-2.1-2.1-2.0-2.1-2.3-2.0-2.1-2.1-2.1-2.1-2.1-2.1-2.0-2.1-2.1-2.0-2.0
Cocaine response after cond. corrected0.50.61.51.21.21.21.00.60.51.00.70.81.10.80.80.80.70.60.60.20.40.40.20.2
Cocaine response after cond. not corrected0.60.71.11.01.01.01.00.60.71.00.81.01.00.80.90.90.90.80.80.40.70.70.50.5
Cocaine response before conditioning0.20.20.8-0.9-0.8-0.8-0.6-0.4-0.2-0.6-0.3-0.3-0.7-0.4-0.3-0.3-0.1-0.2-0.2-0.00.10.00.00.0
Saline control response0.10.20.3-0.4-0.3-0.3-0.3-0.6-0.6-0.3-0.5-0.4-0.2-0.5-0.6-0.5-0.4-0.4-0.4-0.2-0.3-0.3-0.2-0.2
Bone: connectivity density2.23.54.9-1.0-1.2-1.2-1.8-1.9-2.2-1.8-2.1-1.8-1.6-1.9-1.9-2.0-2.1-2.0-2.0-2.1-1.9-1.9-2.1-2.1
Bone: cortical apparent density0.30.41.10.50.50.50.70.80.40.60.60.71.10.80.80.90.50.70.70.50.60.60.50.5
Bone: cortical area0.40.61.00.80.80.81.00.50.61.00.50.70.90.40.50.40.70.60.50.90.80.80.90.9
Bone: cortical porosity0.00.00.1-0.0-0.1-0.1-0.0-0.1-0.1-0.1-0.1-0.0-0.1-0.2-0.0-0.1-0.1-0.1-0.1-0.3-0.2-0.2-0.3-0.3
Bone: cortical porosity0.50.50.7-0.6-0.7-0.7-0.6-0.7-0.7-0.7-0.8-0.7-0.6-0.8-0.6-0.7-0.8-0.7-0.7-0.8-0.8-0.7-0.8-0.8
Bone: cortical thickness2.33.75.02.12.12.12.21.71.72.11.72.02.21.71.81.71.91.81.72.01.92.02.02.0
Bone: cortical thickness0.10.10.20.20.20.20.4-0.0-0.00.30.10.30.50.20.20.20.30.30.20.30.20.30.30.3
Bone: cortical tissue density0.30.41.00.40.40.40.70.70.30.60.50.71.00.70.70.80.50.60.70.40.60.50.40.4
Condit. Reinf. active minus inactive responses3.13.55.22.32.22.22.22.01.92.11.81.82.11.71.81.91.71.71.71.61.71.71.61.6
Condit. Reinf. active-inactive response ratio1.51.73.41.91.71.71.71.31.21.51.11.11.51.01.11.21.11.11.11.01.11.11.01.0
Condit. Reinf. active responses0.50.61.21.00.90.91.10.80.81.00.70.81.00.60.80.90.70.70.70.50.60.70.50.5
Condit. Reinf. inactive responses0.91.21.7-1.2-1.1-1.1-1.0-1.0-1.0-1.0-1.0-0.9-1.0-1.2-0.8-0.8-1.0-1.0-1.0-1.3-1.3-1.2-1.3-1.3
Incentive salience index mean1.21.52.41.51.41.41.51.31.31.41.11.11.41.01.21.21.11.11.10.91.01.10.90.9
Condit. Reinf. lever presses0.00.10.20.20.20.20.50.10.30.40.20.20.30.00.30.30.30.30.3-0.00.10.20.00.0
Condit. Reinf. active minus inactive responses0.00.00.10.10.10.10.0-0.2-0.2-0.1-0.10.20.0-0.1-0.1-0.1-0.1-0.2-0.3-0.30.10.1-0.4-0.4
Condit. Reinf. active-inactive response ratio0.10.10.40.60.60.60.60.10.30.40.30.50.30.20.30.20.30.20.1-0.30.20.1-0.3-0.3
Condit. Reinf. active responses0.30.50.90.70.80.80.80.50.50.70.60.90.80.70.70.70.70.70.50.50.90.90.50.5
Condit. Reinf. inactive responses0.20.20.60.20.20.20.20.30.30.30.40.40.40.40.40.50.50.50.40.80.70.70.80.8
Condit. Reinf. lever presses0.40.61.00.40.40.40.30.80.80.30.80.80.40.81.01.00.91.00.90.91.01.00.90.9
Condit. Reinf. lever reinforcers received0.60.81.31.01.01.00.90.80.70.90.81.11.00.90.90.90.90.90.80.81.11.10.70.7
Conditioned reinforcement - actives0.20.30.7-0.4-0.3-0.3-0.2-0.8-0.8-0.3-0.6-0.4-0.0-0.6-0.4-0.5-0.4-0.4-0.5-0.5-0.6-0.5-0.6-0.6
Conditioned reinforcement - inactives0.30.40.6-0.7-0.6-0.6-0.7-0.8-0.7-0.6-0.7-0.6-0.6-0.7-0.6-0.6-0.5-0.4-0.5-0.6-0.7-0.7-0.6-0.6
Conditioned locomotion0.10.10.40.30.20.20.3-0.1-0.20.3-0.2-0.10.6-0.1-0.0-0.00.10.30.10.40.20.30.40.4
Patch foraging indifference point 0 sec0.40.70.9-0.7-0.7-0.7-0.9-0.9-0.8-0.8-0.8-0.9-0.9-0.8-1.0-0.9-0.9-0.9-0.8-0.8-0.8-0.8-0.8-0.8
Patch foraging indifference point AUC1.01.42.6-1.2-1.2-1.2-1.3-1.2-0.8-1.3-0.9-1.2-1.6-1.1-1.2-1.1-1.0-1.2-1.2-1.2-1.2-1.2-1.2-1.2
Delay disc. indifference point, 0s delay1.41.52.41.21.21.21.41.31.21.31.31.61.51.41.41.21.31.31.30.90.91.00.90.9
Delay disc. indifference point, 16s delay0.00.00.00.0-0.0-0.00.1-0.0-0.10.1-0.10.10.2-0.1-0.00.00.00.00.00.1-0.1-0.20.00.0
Delay disc. indifference point, 2s delay0.91.01.71.01.01.01.11.10.91.00.91.21.31.01.11.00.91.11.10.90.80.80.90.9
Delay disc. indifference point, 24s delay1.41.52.7-1.1-1.1-1.1-1.1-1.5-1.6-1.1-1.5-1.2-0.7-1.5-1.2-1.1-1.2-1.2-1.3-1.0-1.4-1.4-1.1-1.1
Delay disc. indifference point, 4s delay0.10.10.20.30.40.40.20.40.40.30.20.40.40.00.30.40.30.40.40.40.00.00.50.5
Delay disc. indifference point, 8s delay0.00.00.1-0.4-0.3-0.3-0.2-0.1-0.3-0.2-0.1-0.20.00.1-0.1-0.0-0.2-0.1-0.00.3-0.3-0.20.10.1
Indifference point function ln k0.00.00.20.10.10.10.3-0.1-0.20.3-0.10.20.40.10.10.10.20.20.10.20.20.20.20.2
Indifference point function log k0.00.00.20.10.10.10.3-0.1-0.20.3-0.10.20.40.10.10.10.20.20.10.20.20.20.20.2
Patch foraging total patch changes 0 sec0.30.60.9-0.6-0.6-0.6-0.8-0.9-0.8-0.8-0.8-0.9-0.8-0.8-0.9-0.9-0.8-0.8-0.8-0.7-0.7-0.7-0.7-0.7
Patch foraging total patch changes 12 sec0.00.00.10.00.00.00.0-0.20.20.0-0.0-0.2-0.4-0.2-0.2-0.2-0.1-0.2-0.2-0.3-0.3-0.3-0.3-0.3
Patch foraging total patch changes 18 sec1.52.33.3-1.8-1.7-1.7-1.7-1.4-1.3-1.8-1.2-1.5-1.8-1.2-1.4-1.4-1.4-1.5-1.5-1.6-1.4-1.5-1.6-1.6
Patch foraging total patch changes 24 sec0.00.00.30.60.50.50.1-0.00.20.20.2-0.2-0.00.2-0.10.00.1-0.00.0-0.1-0.0-0.0-0.1-0.1
Patch foraging total patch changes 6 sec0.10.10.3-0.0-0.1-0.1-0.3-0.3-0.0-0.3-0.2-0.4-0.6-0.4-0.4-0.3-0.3-0.4-0.3-0.5-0.5-0.5-0.5-0.5
Patch foraging time to switch 0 sec0.10.10.50.40.40.40.60.50.10.50.20.50.70.20.50.3-0.00.20.3-0.10.10.1-0.1-0.1
Patch foraging water rate 0 sec0.51.01.9-0.8-0.9-0.9-1.1-1.4-1.1-1.0-1.1-1.2-1.1-1.0-1.3-1.2-0.8-0.9-1.0-0.6-0.9-0.9-0.6-0.6
Patch foraging water rate 12 sec0.81.73.01.71.61.61.41.11.21.41.31.21.41.31.21.21.41.31.21.21.01.01.21.2
Patch foraging water rate 18 sec0.30.41.01.00.80.80.50.20.60.60.60.50.50.60.40.50.90.70.60.80.60.60.70.7
Patch foraging water rate 24 sec0.00.00.10.30.20.2-0.0-0.2-0.10.0-0.20.0-0.0-0.2-0.2-0.2-0.0-0.1-0.10.1-0.1-0.10.10.1
Patch foraging water rate 6 sec0.20.40.60.70.70.70.50.30.50.60.50.50.60.50.50.50.80.60.60.70.50.40.70.7
Seeking ratio, delayed vs. immediate footshock0.30.41.30.10.20.20.40.70.80.50.70.60.20.60.60.50.60.60.61.10.70.80.90.9
Distance traveled before self-admin0.00.10.4-0.6-0.6-0.6-0.2-0.0-0.1-0.2-0.1-0.2-0.1-0.1-0.1-0.0-0.1-0.1-0.10.00.00.10.20.2
Distance traveled after self-admin0.10.10.7-0.8-0.8-0.8-0.5-0.1-0.0-0.30.0-0.3-0.50.0-0.2-0.0-0.2-0.2-0.10.00.30.30.10.1
Extensor digitorum longus weight0.41.42.1-1.3-1.2-1.2-1.2-1.4-1.5-1.3-1.3-1.1-0.9-1.1-1.2-1.1-1.2-1.1-1.1-1.3-1.0-1.0-1.3-1.3
Bone: elastic displacement0.30.30.6-0.7-0.6-0.6-0.5-0.7-0.8-0.5-0.7-0.6-0.3-0.6-0.5-0.5-0.6-0.5-0.6-0.6-0.5-0.5-0.6-0.6
Bone: elastic work0.10.10.3-0.5-0.4-0.4-0.3-0.5-0.6-0.3-0.5-0.3-0.1-0.4-0.3-0.4-0.4-0.3-0.3-0.3-0.1-0.1-0.3-0.3
Bone: endosteal estimation1.22.52.9-1.6-1.7-1.7-1.6-1.5-1.5-1.5-1.6-1.5-1.6-1.6-1.5-1.6-1.6-1.6-1.5-1.6-1.6-1.6-1.6-1.6
Bone: endosteal perimeter0.51.12.0-1.4-1.4-1.4-1.1-1.1-1.0-1.0-1.0-1.1-1.2-1.1-1.1-1.1-1.0-1.0-1.1-0.7-0.9-0.9-0.7-0.7
Epididymis fat weight2.910.113.53.63.73.73.33.53.53.43.22.92.72.92.82.82.92.72.63.52.82.83.53.5
Delta time in closed arm before/after self-admin0.60.61.3-1.1-0.9-0.9-0.4-0.8-0.7-0.6-0.6-0.7-0.7-0.5-0.7-0.7-0.7-0.7-0.7-0.6-0.9-0.9-0.9-0.9
Delta time in open arm before/after self-admin0.10.10.30.20.10.1-0.00.30.20.10.20.10.00.10.10.40.20.10.10.60.40.20.40.4
Diff in mean of infusions in LGA sessions0.00.00.2-0.1-0.1-0.1-0.20.1-0.0-0.1-0.0-0.1-0.1-0.0-0.0-0.0-0.1-0.10.00.3-0.1-0.10.50.5
Delay discount exponential model param0.00.00.10.10.00.00.00.00.20.00.10.0-0.20.00.0-0.10.0-0.0-0.0-0.20.20.2-0.1-0.1
Extinction: sum of active levers before priming1.11.21.8-1.2-1.1-1.1-1.2-1.1-1.0-1.2-1.0-1.0-1.1-0.9-1.1-0.9-1.0-1.0-1.0-1.0-1.3-1.3-1.2-1.2
Active lever presses in extinction session 60.80.81.2-1.0-1.0-1.0-0.7-0.9-0.7-0.7-0.7-0.8-0.8-0.6-0.8-0.8-0.8-0.9-0.7-1.1-0.9-0.9-1.1-1.1
Bone: final force0.30.50.91.00.80.80.70.70.80.70.70.80.60.60.60.60.70.60.70.80.70.80.80.8
Bone: final moment0.20.30.50.70.60.60.50.50.60.50.50.60.40.40.50.50.50.50.50.60.60.60.60.6
Food consumed during 24 hour testing period0.10.10.3-0.2-0.2-0.3-0.20.20.5-0.10.50.1-0.30.50.20.40.40.30.20.40.30.30.40.4
Glucose0.00.00.20.50.30.30.10.1-0.10.1-0.1-0.10.2-0.1-0.1-0.1-0.1-0.2-0.20.10.10.10.10.1
Heart weight0.20.20.40.40.40.40.60.60.60.50.60.40.30.40.60.50.50.40.40.50.50.50.50.5
Delay discount hyperbolic model param0.00.00.2-0.1-0.1-0.1-0.1-0.2-0.0-0.1-0.1-0.2-0.4-0.1-0.1-0.3-0.1-0.2-0.2-0.40.10.1-0.3-0.3
Intermittent access intake day 1-15 change0.10.30.8-0.3-0.3-0.3-0.4-0.6-0.9-0.5-0.8-0.4-0.1-0.6-0.5-0.5-0.7-0.5-0.5-0.4-0.5-0.9-0.4-0.4
Intermittent access intake escalation0.10.10.5-0.1-0.1-0.1-0.2-0.4-0.7-0.3-0.6-0.30.1-0.4-0.3-0.4-0.5-0.4-0.4-0.2-0.3-0.7-0.2-0.2
Intermittent access intake escalation 20.30.40.9-0.4-0.5-0.4-0.7-0.7-1.0-0.7-0.8-0.5-0.2-0.7-0.6-0.6-0.8-0.7-0.6-0.5-0.5-0.8-0.4-0.4
Intermitt. access day 1 inactive lever presses0.00.00.30.20.20.20.00.10.20.1-0.00.00.0-0.30.1-0.20.10.10.00.4-0.1-0.20.50.5
Intermitt. access day 15 inactive lever presses0.30.61.3-1.2-1.1-1.1-1.0-0.7-0.5-0.9-0.7-0.9-1.1-0.9-0.8-0.9-0.6-0.6-0.70.1-0.3-0.40.10.1
Intermitt. access escalation Index0.00.10.2-0.0-0.0-0.0-0.20.40.3-0.10.3-0.1-0.10.4-0.10.3-0.00.00.20.00.50.50.10.1
Intermittent access day 1 total infusions0.00.00.10.10.10.10.3-0.00.10.30.10.20.30.20.20.20.30.30.2-0.0-0.10.0-0.2-0.2
Intermittent access day 15 total infusions0.10.10.40.40.40.40.4-0.0-0.10.3-0.00.20.70.10.20.20.10.20.20.2-0.1-0.20.00.0
Intermittent access terminal intake (last 3 days)0.50.61.30.80.80.80.90.50.50.80.60.81.10.70.80.80.80.90.80.90.80.70.70.7
Intermittent access total infusions0.20.30.90.60.60.60.80.20.20.60.30.50.90.40.50.50.60.60.50.40.10.30.10.1
Intermittent access day 1 locomotion1.21.52.31.21.21.21.41.11.11.41.11.21.51.31.21.31.41.41.31.21.01.21.01.0
Intermittent access day 15 total locomotion0.91.62.31.31.41.41.41.21.11.41.11.21.51.21.21.21.31.31.21.51.00.91.31.3
Intermittent access total locomotion1.72.14.11.71.71.71.81.11.01.71.11.42.01.21.41.31.41.51.41.41.11.11.21.2
Intermittent access standard deviation0.20.31.0-0.4-0.5-0.5-0.3-0.5-0.6-0.5-0.5-0.2-0.3-0.4-0.2-0.4-0.5-0.4-0.4-0.9-1.0-0.9-0.9-0.9
Left kidney weight0.00.00.10.30.20.2-0.00.1-0.0-0.0-0.1-0.00.0-0.20.0-0.1-0.2-0.2-0.1-0.1-0.10.0-0.1-0.1
Right kidney weight0.10.20.70.80.80.80.70.50.50.70.40.50.50.30.40.20.30.20.20.30.20.20.30.3
Cocaine induced anxiety1.41.92.8-1.5-1.5-1.5-1.3-1.4-1.7-1.4-1.6-1.5-1.1-1.6-1.5-1.5-1.6-1.4-1.4-1.0-1.1-1.5-1.1-1.1
Post-drug Anxiety0.40.40.7-0.8-0.7-0.7-0.7-0.6-0.6-0.7-0.6-0.7-0.8-0.8-0.7-0.7-0.6-0.7-0.8-0.1-0.3-0.6-0.1-0.1
Baseline Anxiety1.61.83.31.31.21.21.01.31.61.11.51.20.61.31.21.21.41.21.11.81.51.51.81.8
Tail length0.00.00.10.10.20.20.10.10.00.10.00.20.20.00.20.20.00.10.1-0.2-0.2-0.2-0.2-0.2
Length with tail0.31.42.51.51.61.61.51.11.01.41.01.11.51.11.01.01.01.01.11.20.90.91.21.2
Length without tail0.31.12.01.41.41.41.40.81.01.31.00.91.21.10.80.81.00.90.91.00.70.71.01.0
Times rat made contact with spout1.82.12.6-1.2-1.3-1.3-1.4-1.5-1.4-1.4-1.4-1.6-1.4-1.4-1.5-1.4-1.4-1.4-1.4-1.5-1.6-1.6-1.5-1.5
Lifetime Intake0.30.41.00.80.80.80.90.30.40.80.40.61.00.60.60.60.70.80.60.50.20.40.20.2
Liver weight, left4.98.08.92.92.92.92.82.83.02.82.92.92.72.82.92.92.92.92.92.62.92.92.62.6
Liver weight, right1.12.02.71.71.61.61.61.61.31.61.31.41.61.41.51.61.21.31.30.91.41.40.90.9
Locomotor activity0.61.01.60.91.01.01.01.31.31.11.10.90.91.01.11.20.90.91.10.70.90.90.70.7
Locomotor testing distance0.10.10.40.10.20.20.30.60.50.30.40.20.10.30.40.30.20.20.30.20.30.30.30.3
Locomotor testing rearing0.00.10.20.30.30.30.10.50.40.20.40.40.20.20.40.30.20.30.40.20.20.30.30.3
Locomotion in novel chamber2.33.03.81.91.91.91.71.81.71.81.71.91.81.81.81.81.81.81.81.51.61.51.21.2
Locomotion in novel chamber post-restriction0.71.11.80.70.90.91.01.11.21.21.11.31.01.01.21.11.21.21.01.11.01.11.01.0
Fecal boli incidents, locomotor time 10.50.71.3-0.7-0.8-0.8-0.8-0.9-1.1-0.7-1.1-1.0-0.4-1.1-0.9-0.7-0.8-0.7-0.8-0.9-0.7-0.6-0.8-0.8
Change in fecal boli incidents, locomotor task0.30.30.60.60.60.60.80.60.70.60.70.70.30.60.70.40.50.40.50.30.0-0.00.10.1
Time >=10cm from walls, locomotor time 10.50.61.1-1.0-1.0-1.0-1.0-0.7-1.0-0.8-0.8-0.9-0.7-0.7-0.8-0.6-0.8-0.7-0.8-0.3-0.2-0.2-0.3-0.3
Bouts of movement, locomotor time 10.10.10.3-0.5-0.5-0.5-0.50.2-0.0-0.3-0.2-0.2-0.1-0.3-0.10.20.10.20.20.30.20.20.60.6
Total resting periods, locomotor time 10.30.30.8-0.8-0.8-0.8-0.9-0.3-0.5-0.7-0.7-0.6-0.4-0.8-0.6-0.4-0.4-0.3-0.20.1-0.2-0.20.40.4
Rest time, locomotor task time 10.10.20.5-0.5-0.5-0.5-0.7-0.1-0.4-0.5-0.5-0.5-0.3-0.5-0.5-0.5-0.4-0.2-0.20.10.20.20.50.5
Distance moved, locomotor task time 10.30.41.20.80.70.70.70.50.70.71.00.60.41.10.70.80.60.50.50.30.30.3-0.0-0.0
Vertical activity count, locomotor time 10.30.71.41.11.01.00.80.70.80.91.00.90.81.21.00.90.90.80.80.30.60.60.10.1
Time >=10cm from walls, locomotor time 21.21.72.4-1.5-1.5-1.5-1.3-1.4-1.6-1.4-1.5-1.2-1.1-1.4-1.2-1.2-1.2-1.2-1.4-0.9-1.4-1.4-0.9-0.9
Bouts of movement, locomotor time 20.10.10.4-0.1-0.0-0.00.10.20.10.1-0.00.30.3-0.20.20.20.30.30.30.6-0.1-0.20.60.6
Total resting periods, locomotor time 20.00.00.2-0.3-0.2-0.2-0.00.1-0.0-0.1-0.20.10.1-0.3-0.00.10.10.20.10.4-0.2-0.30.40.4
Rest time, locomotor task time 20.10.10.3-0.3-0.3-0.3-0.5-0.1-0.3-0.3-0.5-0.5-0.2-0.4-0.5-0.3-0.3-0.2-0.20.20.0-0.00.30.3
Distance moved, locomotor task time 20.70.91.61.00.90.90.90.91.10.81.21.00.71.31.11.11.01.01.00.50.80.90.50.5
Vertical activity count, locomotor time 20.10.10.30.20.20.20.10.30.30.10.50.20.10.60.50.50.50.50.4-0.00.50.50.00.0
Light reinforcement 10.10.20.5-0.20.00.00.30.50.40.30.40.20.40.40.40.40.30.40.50.40.50.70.40.4
Light reinforcement 20.10.20.5-0.5-0.4-0.4-0.4-0.5-0.5-0.5-0.4-0.4-0.3-0.4-0.3-0.3-0.4-0.4-0.4-0.7-0.4-0.3-0.7-0.7
Bone: marrow area1.02.32.7-1.6-1.6-1.6-1.5-1.4-1.5-1.4-1.5-1.4-1.5-1.5-1.5-1.5-1.5-1.5-1.5-1.5-1.5-1.5-1.5-1.5
Bone: maximum diameter0.30.61.1-0.8-0.8-0.8-0.6-1.0-0.7-0.5-0.8-0.7-0.8-1.0-0.8-1.0-0.6-0.8-0.9-0.4-0.7-0.7-0.4-0.4
Bone: maximum force0.10.20.40.60.50.50.40.40.50.40.40.60.30.30.40.40.40.40.50.40.50.50.40.4
Bone: maximum moment0.00.10.10.40.30.30.20.20.30.20.20.40.20.20.20.20.20.20.30.20.30.30.20.2
Mean time between licks in bursts0.10.20.6-0.7-0.7-0.7-0.80.10.1-0.50.0-0.3-0.6-0.1-0.0-0.0-0.0-0.0-0.10.30.20.20.40.4
Mean num. licks in bursts2.03.14.0-1.7-1.7-1.7-1.7-2.0-1.9-1.7-1.9-1.9-1.6-1.8-1.8-1.8-1.7-1.7-1.7-1.7-1.7-1.7-1.7-1.7
Cd content in liver0.30.30.5-0.6-0.6-0.6-0.7-0.4-0.5-0.6-0.4-0.6-0.7-0.3-0.6-0.4-0.5-0.6-0.6-0.4-0.5-0.6-0.5-0.5
Co content in liver0.00.00.0-0.2-0.2-0.2-0.1-0.1-0.2-0.1-0.00.10.10.10.00.00.00.10.1-0.1-0.1-0.1-0.1-0.1
Cu content in liver0.10.10.4-0.3-0.4-0.4-0.20.0-0.4-0.2-0.4-0.4-0.1-0.3-0.4-0.2-0.6-0.4-0.2-0.4-0.6-0.6-0.4-0.4
Fe content in liver2.42.93.6-1.6-1.6-1.6-1.9-1.7-1.7-1.8-1.8-1.8-1.8-1.8-1.9-1.8-1.8-1.7-1.6-1.5-1.7-1.7-1.5-1.5
K content in liver0.10.10.30.40.40.30.50.40.50.50.30.30.20.10.20.20.20.20.20.10.10.10.20.2
Mg content in liver0.00.00.2-0.0-0.0-0.0-0.00.0-0.1-0.0-0.2-0.10.0-0.2-0.2-0.1-0.3-0.2-0.1-0.3-0.4-0.4-0.3-0.3
Mn content in liver0.40.50.90.70.80.80.70.80.50.70.60.70.90.70.70.70.50.70.70.50.60.60.50.5
Na content in liver0.10.10.2-0.1-0.1-0.1-0.2-0.4-0.2-0.2-0.3-0.3-0.3-0.4-0.3-0.3-0.1-0.2-0.2-0.3-0.4-0.4-0.3-0.3
Rb content in liver1.72.02.6-1.6-1.6-1.6-1.6-1.1-1.1-1.5-1.3-1.4-1.6-1.5-1.5-1.4-1.4-1.4-1.3-1.1-1.4-1.5-1.1-1.1
Se content in liver0.60.71.10.50.40.40.70.90.90.80.90.80.80.90.80.90.80.91.01.00.90.91.01.0
Sr content in liver0.80.71.0-0.9-0.9-0.9-0.9-0.9-1.0-0.9-0.9-0.8-0.7-0.8-0.8-0.8-0.8-0.7-0.7-0.9-0.7-0.7-0.9-0.9
Zn content in liver0.50.51.01.00.90.90.60.90.90.70.60.60.50.50.60.70.70.70.70.80.40.30.80.8
Bone: minimum diameter0.50.91.40.90.90.91.21.01.01.20.91.01.00.80.80.90.90.90.91.00.90.91.01.0
Time in familiar zone, hab. session 10.90.91.41.00.90.90.80.90.90.81.00.90.81.20.80.80.90.90.91.01.11.11.01.0
Time in novel zone, hab. session 10.40.40.6-0.7-0.6-0.6-0.7-0.4-0.5-0.6-0.6-0.7-0.6-0.8-0.6-0.5-0.7-0.7-0.6-0.5-0.7-0.7-0.6-0.6
Total zone transitions, hab. session 10.20.20.5-0.3-0.4-0.4-0.7-0.6-0.4-0.6-0.4-0.7-0.7-0.5-0.5-0.5-0.3-0.4-0.5-0.2-0.4-0.4-0.3-0.3
Total locomotion distance, hab. session 10.00.00.1-0.3-0.3-0.3-0.3-0.3-0.1-0.2-0.1-0.3-0.1-0.0-0.1-0.00.10.0-0.00.1-0.0-0.00.10.1
Locomotion velocity, hab. session 10.00.00.1-0.1-0.1-0.1-0.1-0.2-0.00.00.1-0.2-0.00.00.10.10.30.20.10.10.10.10.10.1
Time in familiar zone, hab. session 20.00.00.10.20.20.20.10.0-0.10.1-0.1-0.10.20.0-0.1-0.1-0.1-0.00.10.00.10.10.00.0
Time in novel zone, hab. session 20.10.10.1-0.2-0.2-0.2-0.3-0.1-0.3-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.3-0.3-0.3-0.2-0.3-0.4-0.2-0.2
Total zone transitions, hab. session 20.91.11.8-1.0-1.0-1.0-1.2-1.2-1.0-1.1-1.1-1.3-1.3-1.1-1.1-1.1-1.0-1.1-1.1-0.9-0.9-0.9-0.9-0.9
Total locomotion distance, hab. session 21.21.62.1-1.4-1.4-1.4-1.4-1.3-1.1-1.3-1.2-1.5-1.4-1.2-1.3-1.2-1.2-1.2-1.2-1.1-1.1-1.1-1.1-1.1
Locomotion velocity, hab. session 21.21.72.3-1.5-1.4-1.4-1.5-1.4-1.1-1.3-1.2-1.5-1.5-1.2-1.3-1.3-1.2-1.2-1.2-1.1-1.2-1.1-1.1-1.1
Novel to familiar place preference ratio0.00.00.10.10.10.10.00.20.10.10.10.10.20.1-0.1-0.1-0.00.10.10.30.30.30.30.3
Novelty place preference0.30.30.60.50.40.40.40.60.50.50.50.50.50.60.30.40.40.50.50.70.70.70.80.8
Time in novel zone, NPP test0.10.10.40.30.20.20.20.40.30.30.30.40.40.30.10.10.20.30.30.60.50.50.60.6
Total zone transitions, NPP test1.52.13.3-1.7-1.7-1.7-1.8-1.5-1.4-1.7-1.3-1.6-1.8-1.3-1.4-1.4-1.3-1.4-1.5-1.1-1.2-1.2-1.1-1.1
Total locomotion distance, NPP test2.02.73.5-1.9-1.8-1.8-1.8-1.6-1.6-1.7-1.6-1.8-1.7-1.5-1.6-1.6-1.6-1.6-1.6-1.5-1.5-1.5-1.5-1.5
Locomotion velocity, NPP test1.52.13.1-1.8-1.7-1.7-1.6-1.5-1.4-1.5-1.3-1.6-1.6-1.3-1.4-1.4-1.3-1.4-1.4-1.3-1.3-1.3-1.3-1.3
Intraocular pressure0.30.40.60.80.70.70.60.70.50.60.50.60.70.50.60.60.50.50.40.70.60.60.60.6
Delta distance traveled before/after self-admin0.20.20.40.30.20.20.20.50.70.20.60.4-0.10.50.40.40.30.30.40.40.60.60.30.3
Delta ambulatory time before/after self-admin0.00.10.2-0.2-0.2-0.2-0.4-0.2-0.1-0.3-0.2-0.3-0.4-0.2-0.3-0.2-0.3-0.3-0.2-0.00.10.1-0.2-0.2
Parametrial fat weight8.620.225.85.15.05.04.75.05.04.64.84.34.24.64.54.64.34.24.24.04.14.04.04.0
Pavlov. Cond. lever latency0.30.30.70.80.80.80.60.50.50.60.50.60.60.60.40.40.50.50.50.60.50.50.60.6
Pavlov. Cond. magazine entry latency0.60.81.0-1.0-0.9-0.9-0.7-1.0-0.9-0.8-0.9-0.9-0.8-0.8-0.8-0.8-0.8-0.9-0.9-1.0-0.9-0.8-1.0-1.0
Pavlov. Cond. change in total contacts0.00.00.2-0.1-0.0-0.00.20.0-0.20.1-0.10.00.40.10.20.20.00.10.1-0.2-0.1-0.0-0.1-0.1
Pavlov. Cond. index score0.30.40.7-0.7-0.7-0.7-0.5-0.7-0.7-0.6-0.7-0.7-0.5-0.6-0.5-0.5-0.6-0.6-0.6-0.8-0.7-0.7-0.8-0.8
Pavlov. Cond. latency score0.60.70.9-0.9-0.9-0.9-0.8-0.9-0.9-0.8-0.9-1.0-0.8-0.8-0.8-0.8-0.8-0.8-0.8-0.9-0.8-0.8-0.9-0.9
Pavlov. Cond. lever contacts0.10.10.2-0.4-0.4-0.4-0.2-0.2-0.1-0.2-0.2-0.2-0.2-0.3-0.0-0.0-0.1-0.1-0.1-0.3-0.3-0.2-0.3-0.3
Pavlov. Cond. magazine entry number1.31.62.01.41.31.31.11.31.31.21.21.31.11.21.11.11.21.21.31.41.31.31.41.4
Pavlov. Cond. intertrial magazine entries0.30.30.60.0-0.0-0.0-0.2-0.7-0.7-0.3-0.7-0.5-0.1-0.7-0.6-0.6-0.6-0.6-0.6-0.8-0.7-0.7-0.7-0.7
Pavlov. Cond. lever-magazine prob. diff.0.40.60.9-0.8-0.7-0.7-0.6-0.8-0.8-0.6-0.8-0.8-0.6-0.7-0.6-0.6-0.7-0.7-0.7-1.0-0.8-0.7-1.0-1.0
Pavlov. Cond. response bias1.01.31.8-1.3-1.3-1.3-0.9-1.2-1.1-1.0-1.1-1.1-1.0-1.1-0.9-0.9-1.0-1.0-1.1-1.3-1.1-1.1-1.3-1.3
Pavlov. Cond. lever latency0.30.51.10.70.80.81.00.60.50.90.60.81.00.80.70.70.60.60.60.40.60.60.40.4
Pavlov. Cond. magazine entry latency0.50.61.0-0.6-0.7-0.7-1.0-0.5-0.5-0.9-0.7-0.9-1.0-0.9-0.6-0.7-0.8-0.8-0.8-0.7-0.7-0.7-0.7-0.7
Pavlov. Cond. change in total contacts0.10.20.7-0.6-0.6-0.7-0.8-0.1-0.1-0.7-0.2-0.4-0.8-0.3-0.3-0.2-0.3-0.3-0.3-0.0-0.1-0.1-0.0-0.0
Pavlov. Cond. index score0.40.51.2-0.7-0.8-0.8-1.1-0.5-0.4-1.0-0.5-0.8-1.1-0.7-0.6-0.6-0.6-0.6-0.6-0.5-0.5-0.5-0.5-0.5
Pavlov. Cond. latency score0.50.71.4-0.9-1.0-1.0-1.2-0.6-0.5-1.1-0.7-0.9-1.2-0.9-0.7-0.8-0.8-0.8-0.8-0.7-0.7-0.7-0.7-0.7
Pavlov. Cond. lever contacts0.10.20.7-0.4-0.5-0.5-0.8-0.3-0.2-0.7-0.3-0.5-0.8-0.5-0.4-0.4-0.3-0.3-0.4-0.1-0.3-0.3-0.1-0.1
Pavlov. Cond. magazine entry number0.50.61.00.80.90.91.00.50.50.90.60.91.00.80.60.70.80.80.70.60.70.70.60.6
Pavlov. Cond. intertrial magazine entries1.21.82.81.51.51.51.61.31.11.41.31.41.71.41.41.41.31.31.31.11.21.21.11.1
Pavlov. Cond. lever-magazine prob. diff.0.40.51.3-0.8-0.9-0.9-1.1-0.5-0.4-1.0-0.6-0.8-1.1-0.8-0.6-0.6-0.7-0.6-0.6-0.6-0.6-0.6-0.5-0.5
Pavlov. Cond. response bias0.60.81.6-0.8-1.0-1.0-1.3-0.8-0.6-1.1-0.8-0.9-1.3-0.9-0.8-0.8-0.8-0.8-0.8-0.6-0.7-0.7-0.6-0.6
Time in closed arm before self-admin0.20.20.6-0.1-0.2-0.2-0.6-0.3-0.2-0.6-0.4-0.3-0.8-0.6-0.3-0.4-0.5-0.5-0.4-0.5-0.4-0.5-0.7-0.7
Time in closed arm after self-admin0.70.71.20.90.90.90.90.81.10.91.01.00.60.80.90.80.90.80.80.80.80.90.60.6
Time in open arm before self-admin0.40.40.70.40.50.50.90.60.60.70.70.70.80.80.70.80.70.70.70.30.30.50.60.6
Time in open arm after self-admin0.00.00.1-0.3-0.3-0.3-0.2-0.0-0.3-0.2-0.3-0.20.1-0.2-0.2-0.1-0.2-0.1-0.10.20.0-0.10.30.3
Bone: periosteal estimation0.20.50.7-0.7-0.7-0.7-0.4-0.8-0.7-0.4-0.8-0.6-0.5-0.9-0.7-0.8-0.7-0.7-0.7-0.5-0.7-0.6-0.5-0.5
Bone: periosteal perimeter0.20.30.6-0.7-0.8-0.8-0.5-0.7-0.5-0.4-0.6-0.6-0.6-0.7-0.7-0.8-0.4-0.5-0.6-0.0-0.3-0.3-0.0-0.0
Bone: post-yield work1.72.53.0-1.6-1.6-1.6-1.6-1.7-1.5-1.7-1.5-1.5-1.7-1.5-1.5-1.5-1.5-1.5-1.5-1.7-1.6-1.6-1.7-1.7
Progressive ratio test 1 active lever presses0.50.71.20.91.01.01.10.60.81.00.70.71.00.80.70.80.90.90.80.80.60.80.50.5
Progressive ratio test 1 breakpoint0.40.40.80.80.90.90.90.50.60.90.50.50.90.60.50.60.70.70.70.70.50.60.30.3
Progressive ratio test 1 inactive lever presses0.00.10.20.20.10.10.20.20.40.30.10.10.20.00.10.10.30.40.30.50.40.20.40.4
Progressive ratio test 2 active lever presses0.30.41.20.60.70.70.70.30.20.60.40.61.10.50.70.60.70.70.60.60.20.40.50.5
Progressive ratio test 2 breakpoint0.50.61.70.80.90.90.90.50.40.80.60.81.30.70.90.80.80.90.80.80.40.60.60.6
Progressive ratio test 2 inactive lever presses0.00.00.2-0.3-0.2-0.2-0.2-0.3-0.2-0.2-0.2-0.10.1-0.2-0.1-0.10.00.0-0.10.1-0.4-0.4-0.0-0.0
Incentive Sensitization - Responses0.10.20.90.30.40.40.30.2-0.10.30.20.60.90.40.60.40.40.50.50.50.20.30.50.5
Incentive Sensitization - Breakpoint0.40.51.50.60.70.70.60.50.20.60.50.91.20.70.90.70.70.80.70.70.40.60.80.8
Sum of active levers in priming session hrs 5-60.50.51.3-0.7-0.6-0.6-0.6-0.6-0.7-0.6-0.5-0.4-0.3-0.4-0.4-0.6-0.6-0.6-0.6-0.9-1.1-1.1-0.8-0.8
Progressive ratio0.30.51.0-0.7-0.7-0.7-0.5-0.6-0.4-0.7-0.6-0.6-0.9-0.7-0.7-0.6-0.6-0.7-0.7-1.0-0.8-0.7-0.9-0.9
Food seeking constrained by brief footshock3.03.64.9-2.2-2.1-2.1-1.9-2.2-2.1-2.0-2.0-2.0-1.7-1.8-2.1-1.9-1.8-1.8-1.9-1.7-1.7-1.6-1.6-1.6
Seeking ratio, punishment vs. effort0.30.40.7-0.7-0.7-0.7-0.9-0.8-0.8-0.7-0.7-0.7-0.5-0.5-0.8-0.7-0.5-0.6-0.6-0.1-0.3-0.3-0.1-0.1
Retroperitoneal fat weight9.741.353.97.27.07.06.67.37.26.56.76.25.76.46.36.36.05.96.06.06.05.96.06.0
Reaction time number correct0.10.30.4-0.4-0.5-0.5-0.6-0.5-0.6-0.6-0.6-0.7-0.5-0.6-0.6-0.4-0.5-0.6-0.6-0.3-0.4-0.4-0.3-0.3
Reaction time mean minus median0.10.30.70.50.60.60.40.60.20.50.40.50.90.50.70.60.40.50.50.60.80.80.50.5
Reaction time mean minus median AUC0.20.50.80.80.80.80.60.80.50.70.60.70.90.60.80.70.50.60.60.60.90.80.60.6
Reaction time num false alarms0.10.10.20.10.10.10.3-0.2-0.10.1-0.2-0.3-0.1-0.5-0.4-0.5-0.3-0.4-0.4-0.1-0.3-0.4-0.1-0.1
Reaction time num false alarms AUC0.00.10.30.40.50.50.60.10.20.50.0-0.00.3-0.1-0.1-0.20.0-0.1-0.10.30.0-0.10.30.3
Reaction time trials correct on left0.10.30.4-0.4-0.5-0.5-0.6-0.5-0.6-0.6-0.6-0.7-0.5-0.6-0.6-0.4-0.5-0.6-0.6-0.3-0.4-0.4-0.3-0.3
Reaction time trials on left0.10.20.4-0.3-0.5-0.5-0.6-0.4-0.5-0.6-0.6-0.6-0.5-0.6-0.6-0.3-0.5-0.5-0.6-0.2-0.3-0.4-0.3-0.3
Reaction time mean0.20.30.90.20.30.30.20.60.00.30.40.51.00.70.60.50.30.50.50.70.90.80.70.7
Reaction time mean AUC0.20.31.00.30.40.40.30.60.10.40.40.61.00.70.60.50.40.50.60.70.90.80.70.7
Median of all reaction times0.10.20.5-0.10.00.0-0.00.4-0.20.00.20.30.70.50.30.30.10.30.40.50.60.60.50.5
Reaction time omissions0.00.10.20.40.40.40.20.30.00.30.10.50.50.20.30.10.10.10.20.10.10.10.10.1
Reaction time false alarm rate0.30.41.10.80.90.91.10.50.60.90.50.50.80.40.40.20.50.40.40.50.40.30.60.6
Reaction time premature initiation rate0.30.41.0-0.7-0.7-0.7-0.8-0.7-0.5-0.7-0.6-1.0-0.9-0.7-0.8-0.7-0.6-0.7-0.6-0.3-0.4-0.4-0.3-0.3
Reaction time premature initiations0.50.81.8-0.9-0.9-0.9-1.1-1.0-0.8-1.0-1.0-1.3-1.1-1.0-1.1-0.9-0.9-1.0-1.0-0.5-0.7-0.7-0.5-0.5
Std. dev. reaction times0.10.20.80.60.60.60.30.50.00.40.20.40.90.40.50.50.30.40.30.40.60.50.40.4
Reaction time trials completed0.10.20.4-0.3-0.5-0.5-0.6-0.4-0.5-0.6-0.6-0.6-0.5-0.6-0.6-0.3-0.5-0.5-0.6-0.2-0.3-0.4-0.3-0.3
Reaction time trials AUC0.00.10.2-0.2-0.3-0.3-0.4-0.2-0.4-0.4-0.4-0.4-0.2-0.4-0.4-0.1-0.3-0.3-0.4-0.0-0.2-0.2-0.1-0.1
Run reversals in cocaine runway, females1.21.22.1-1.1-1.2-1.2-1.1-1.1-0.9-1.2-0.9-1.0-1.2-1.0-0.9-1.0-1.0-1.0-1.0-1.4-0.9-0.9-1.3-1.3
Run reversals in cocaine runway, males0.30.30.70.30.40.40.70.40.70.60.60.70.50.50.70.60.70.60.60.80.60.60.50.5
Latency to leave start box in cocaine runway6.47.310.1-2.4-2.5-2.5-2.7-2.9-2.9-2.6-3.0-3.0-2.6-3.1-3.2-3.0-2.9-2.9-2.9-1.8-2.5-2.4-2.0-2.0
Latency to leave start box in cocaine runway, F3.54.05.9-1.8-1.8-1.8-1.8-2.2-2.1-1.8-2.2-2.2-1.9-2.3-2.4-2.2-2.0-2.2-2.2-1.6-1.8-1.9-1.7-1.7
Latency to leave start box in cocaine runway, M3.63.44.5-1.8-1.9-1.9-2.1-1.8-2.1-2.0-2.1-2.1-1.7-2.0-2.1-2.1-2.1-1.9-2.0-0.9-1.7-1.4-1.0-1.0
Std. dev. time between licks in bursts0.10.20.4-0.4-0.5-0.5-0.6-0.0-0.2-0.3-0.2-0.4-0.4-0.2-0.4-0.3-0.2-0.1-0.20.60.40.30.60.6
Total sessions with >9 infusions0.80.91.81.11.21.21.10.70.71.00.81.01.31.01.01.01.11.21.10.80.50.50.60.6
Short access day 1 total inactive lever presses0.20.20.5-0.1-0.1-0.1-0.2-0.6-0.4-0.2-0.6-0.5-0.1-0.6-0.4-0.5-0.3-0.2-0.4-0.6-0.7-0.6-0.6-0.6
Short access day 10 total inactive lever presses1.63.95.7-2.2-2.3-2.3-2.4-1.9-1.8-2.4-1.9-2.1-2.2-1.9-2.0-1.9-1.9-1.9-2.0-1.7-1.6-1.8-1.6-1.6
Short access day 1 total infusions0.10.10.30.50.50.50.50.10.10.40.10.30.50.20.30.30.30.40.2-0.2-0.3-0.1-0.4-0.4
Short access day 10 total infusions0.00.10.20.30.30.30.3-0.10.00.20.10.20.40.30.20.20.40.30.20.1-0.1-0.0-0.2-0.2
Short access total infusions0.40.50.90.90.90.90.90.50.60.80.70.71.00.80.80.80.90.90.80.50.20.40.20.2
Short access day 1 locomotion0.60.71.51.11.11.10.90.70.60.90.60.81.20.60.90.70.91.00.90.80.40.50.60.6
Short access day 10 total locomotion0.10.20.70.30.40.40.50.40.10.40.30.50.80.50.50.50.40.60.50.20.20.20.20.2
Short access total locomotion1.21.43.31.51.51.51.41.00.81.31.01.31.81.21.31.21.21.41.30.90.60.70.60.6
One hour access (0.3 mA shock)0.70.81.6-0.7-0.6-0.6-0.6-1.0-1.3-0.7-1.0-0.7-0.1-0.8-0.7-0.8-0.9-0.8-0.8-1.0-1.2-1.1-1.1-1.1
Compulsive drug intake0.20.20.7-0.4-0.3-0.3-0.2-0.2-0.5-0.3-0.5-0.3-0.1-0.4-0.4-0.4-0.5-0.4-0.4-0.8-0.6-0.5-0.5-0.5
One hour access (shock baseline)0.00.00.20.00.00.0-0.1-0.4-0.4-0.1-0.2-0.10.3-0.10.0-0.1-0.00.0-0.00.0-0.3-0.2-0.3-0.3
Social response proportion0.50.61.11.01.01.00.90.80.61.10.60.71.10.60.70.70.60.80.80.70.70.60.70.7
Social responses0.00.10.20.10.10.10.10.30.10.30.00.10.2-0.0-0.0-0.00.00.10.10.50.30.30.50.5
Social time1.41.92.51.31.31.31.51.31.11.51.21.51.61.41.21.31.31.41.41.51.51.51.51.5
Soleus weight1.75.06.0-2.4-2.3-2.3-2.3-2.4-2.3-2.4-2.2-2.1-2.2-2.1-2.1-2.1-2.1-2.1-2.1-2.4-2.1-2.2-2.4-2.4
Bone: stiffness0.30.50.80.90.80.80.60.70.80.60.70.80.40.50.70.60.60.60.70.70.70.70.70.7
Tibialis anterior weight0.31.01.4-1.1-1.0-0.9-1.0-1.2-1.2-1.0-1.1-1.0-0.8-1.0-0.9-0.9-1.0-0.9-0.9-1.0-0.8-0.8-1.0-1.0
Time to tail flick, vehicle, before self-admin1.31.41.71.11.11.11.21.11.11.21.11.21.21.11.21.21.31.31.21.11.31.30.90.9
Time to tail flick, vehicle, after self-admin0.30.30.70.30.40.40.60.80.70.70.70.60.50.60.60.60.50.50.60.80.30.40.70.7
Time to tail flick, test, before self-admin0.50.51.21.11.11.10.80.50.40.80.50.81.10.60.80.70.60.70.80.30.20.20.40.4
Time to tail flick, test, after self-admin0.10.10.4-0.1-0.1-0.1-0.1-0.3-0.5-0.2-0.3-0.10.1-0.1-0.1-0.2-0.2-0.1-0.1-0.4-0.6-0.5-0.6-0.6
Delta time to tail flick, vehicle, before/after SA0.50.50.7-0.8-0.8-0.8-0.7-0.6-0.6-0.7-0.7-0.8-0.7-0.7-0.7-0.8-0.8-0.8-0.8-0.4-0.9-0.8-0.4-0.4
Delta time to tail flick, test, before/after SA1.41.41.8-1.3-1.3-1.3-1.1-1.1-1.3-1.2-1.3-1.2-1.0-1.2-1.2-1.3-1.2-1.1-1.1-1.0-1.1-1.0-1.3-1.3
Tibia length1.23.34.22.02.12.11.92.02.01.81.81.81.71.81.81.91.81.71.71.71.51.51.71.7
Ambulatory time before self-admin0.00.10.3-0.5-0.5-0.5-0.10.10.0-0.10.1-0.0-0.00.10.10.10.10.10.00.20.30.30.40.4
Ambulatory time after self-admin0.10.10.6-0.7-0.8-0.8-0.5-0.00.0-0.30.0-0.2-0.5-0.0-0.2-0.0-0.2-0.2-0.10.10.40.40.20.2
Bone: tissue strength1.61.62.11.31.31.31.01.41.21.11.21.21.31.21.31.31.11.31.41.31.31.31.31.3
Total heroin consumption1.01.12.0-1.3-1.1-1.1-1.2-1.2-1.4-1.2-1.2-1.1-0.6-1.0-1.0-0.8-0.9-0.9-0.9-0.9-1.3-1.3-0.8-0.8
Bone: trabecular number2.84.66.0-1.6-1.8-1.8-2.1-2.3-2.5-2.1-2.3-2.0-1.8-2.2-2.2-2.3-2.3-2.2-2.2-2.3-2.1-2.1-2.3-2.3
Bone: trabecular spacing2.93.94.51.51.71.72.02.02.11.92.12.01.82.02.02.12.12.12.02.02.02.02.02.0
Bone: trabecular thickness1.92.33.0-1.2-1.3-1.3-1.5-1.6-1.7-1.4-1.7-1.6-1.3-1.7-1.6-1.7-1.6-1.6-1.6-1.4-1.5-1.5-1.4-1.4
Bone: trabecular tissue density0.40.51.3-1.1-1.1-1.1-0.7-0.6-0.5-0.8-0.5-0.6-0.9-0.5-0.6-0.6-0.6-0.6-0.7-0.7-0.6-0.6-0.6-0.6
Water consumed over 24 hours0.50.60.8-0.8-0.8-0.8-0.7-0.6-0.8-0.7-0.8-0.8-0.7-0.7-0.8-0.8-0.9-0.8-0.8-0.9-0.8-0.8-0.8-0.8
Number of responses in last shaping day0.70.71.7-0.6-0.6-0.6-0.8-0.8-0.8-0.7-0.8-0.8-0.7-0.8-0.7-0.8-0.7-0.7-0.8-1.2-1.1-1.0-1.3-1.3