Hub : Genes

LOC120103632

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Eye	intron excision ratio	chr6_131654175_131655805	0.19	0.14	9.5e-03	0.11	0.08	0.01	0.05	1.0e-02	2.1e-02	2.1e-01	6.1e-02
2	Eye	intron excision ratio	chr6_131654146_131654429	0.32	0.2	2.5e-03	0.13	0.12	0.1	0.08	4.6e-03	6.3e-03	1.2e-02	2.2e-02
3	Adipose	gene expression	LOC120103632	0.05	0.04	1.0e-06	0.05	0.04	0.04	0.04	3.1e-06	9.6e-06	1.1e-05	1.2e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Bone: apparent density	0.0	0.1	0.2	-0.2	-0.4	0.1
Area under the delay curve	0.1	0.1	0.2	0.4	-0.3	-0.4
BMI with tail	1.9	6.3	7.2	2.7	-2.5	-2.3
BMI without tail	0.2	0.5	1.4	1.2	-0.3	-0.1
Body weight	0.7	2.9	4.1	-2.0	1.4	1.7
Weight adjusted by age	0.2	0.2	0.5	-0.7	0.1	-0.2
Bone surface	0.1	0.1	0.2	0.4	-0.4	0.0
Bone volume	0.0	0.1	0.1	0.3	-0.2	0.3
Breakpoint value in progressive ratio session	0.2	0.2	0.3	0.5	-0.2	-0.6
Number of licking bursts	0.1	0.2	0.4	0.6	-0.1	-0.3
Context. condit. distance diff. score	2.9	3.5	4.1	-2.0	1.8	1.8
Locomotion velocity, session 1	0.1	0.1	0.2	-0.5	0.3	0.3
Locomotion distance, session 1	0.5	0.7	1.0	0.6	-0.9	-1.0
Locomotion velocity, session 2	0.0	0.1	0.1	0.3	0.3	-0.0
Locomotion distance, session 2	0.3	0.4	0.5	0.7	-0.6	-0.4
Locomotion velocity, session 3	0.1	0.1	0.2	0.2	-0.4	-0.2
Locomotion distance, session 3	0.0	0.0	0.0	0.0	-0.0	0.1
Stereotopy head waving bouts, day 3	0.1	0.1	0.2	-0.2	0.4	0.3
Stereotopy head waving duration, day 3	0.3	0.3	0.5	-0.3	0.7	0.6
Locomotion velocity, session 7	0.3	0.3	0.5	0.1	-0.7	-0.6
Locomotion distance, session 7	0.7	0.9	1.0	1.0	-1.0	-0.9
Stereotopy head waving bouts, day 7	1.7	1.9	2.8	-1.7	1.0	1.3
Stereotopy head waving duration, day 7	0.6	0.8	1.5	-1.2	0.6	0.7
Locomotion velocity, session 8	0.9	1.1	1.8	-1.3	0.7	1.0
Locomotion distance, session 8	0.2	0.3	0.5	-0.7	0.2	0.5
Degree of sensitization distance	0.3	0.3	0.3	0.5	-0.5	-0.5
Degree of sensitization stereotypy	0.4	0.4	0.9	-1.0	0.2	0.6
Conditioned locomotion	1.3	1.5	1.8	-1.3	1.2	1.1
Cocaine response after cond. corrected	0.6	0.6	1.0	0.6	-0.7	-1.0
Cocaine response after cond. not corrected	1.8	1.9	2.2	1.3	-1.4	-1.5
Cocaine response before conditioning	2.0	2.4	3.1	1.8	-1.7	-1.1
Saline control response	0.1	0.1	0.2	-0.1	-0.4	0.1
Bone: connectivity density	0.2	0.3	0.4	-0.7	0.1	0.7
Bone: cortical apparent density	6.6	8.6	10.5	-2.8	3.2	2.8
Bone: cortical area	0.4	0.7	1.4	-0.6	1.2	0.5
Bone: cortical porosity	0.2	0.2	0.5	-0.5	0.1	0.7
Bone: cortical porosity	0.1	0.1	0.2	-0.2	-0.4	0.2
Bone: cortical thickness	0.4	0.6	0.9	-0.8	1.0	0.4
Bone: cortical thickness	1.0	1.1	1.5	-1.0	0.9	1.2
Bone: cortical tissue density	6.7	8.8	10.8	-2.8	3.3	2.8
Condit. Reinf. active minus inactive responses	0.5	0.6	0.9	0.7	-0.6	-0.9
Condit. Reinf. active-inactive response ratio	2.8	3.0	3.9	1.6	-1.6	-2.0
Condit. Reinf. active responses	0.0	0.1	0.1	0.1	-0.1	-0.4
Condit. Reinf. inactive responses	2.0	2.4	2.7	-1.5	1.6	1.5
Incentive salience index mean	0.4	0.5	0.8	0.4	-0.7	-0.9
Condit. Reinf. lever presses	0.1	0.1	0.2	-0.0	-0.4	-0.4
Condit. Reinf. active minus inactive responses	0.8	1.0	1.2	-0.9	1.0	1.1
Condit. Reinf. active-inactive response ratio	0.8	0.8	1.2	-0.6	1.1	0.9
Condit. Reinf. active responses	0.1	0.2	0.3	-0.3	0.4	0.5
Condit. Reinf. inactive responses	0.2	0.3	0.5	0.5	-0.7	-0.4
Condit. Reinf. lever presses	0.9	1.2	2.0	1.4	-1.0	-0.8
Condit. Reinf. lever reinforcers received	0.2	0.3	0.4	-0.4	0.4	0.7
Conditioned reinforcement - actives	2.3	2.3	3.0	-1.2	1.7	1.5
Conditioned reinforcement - inactives	0.7	0.7	0.9	-0.9	0.8	0.9
Conditioned locomotion	0.1	0.2	0.3	0.3	-0.6	-0.3
Patch foraging indifference point 0 sec	3.8	6.0	7.3	-2.7	2.5	2.2
Patch foraging indifference point AUC	2.1	2.4	3.4	-1.8	1.7	1.0
Delay disc. indifference point, 0s delay	0.3	0.3	0.6	-0.8	0.4	0.6
Delay disc. indifference point, 16s delay	0.3	0.3	0.5	0.7	0.2	-0.7
Delay disc. indifference point, 2s delay	0.6	0.7	0.9	1.0	-0.6	-0.9
Delay disc. indifference point, 24s delay	0.6	0.5	0.8	0.6	-0.7	-0.9
Delay disc. indifference point, 4s delay	0.2	0.2	0.5	-0.3	0.3	0.7
Delay disc. indifference point, 8s delay	0.1	0.1	0.1	0.3	-0.3	-0.1
Indifference point function ln k	1.3	1.8	3.3	-1.2	0.8	1.8
Indifference point function log k	1.3	1.8	3.3	-1.2	0.8	1.8
Patch foraging total patch changes 0 sec	4.5	7.2	8.7	-3.0	2.6	2.4
Patch foraging total patch changes 12 sec	2.8	3.6	4.6	-2.1	2.1	1.4
Patch foraging total patch changes 18 sec	1.1	1.4	1.8	-1.4	1.3	0.8
Patch foraging total patch changes 24 sec	0.3	0.4	0.7	-0.8	0.6	0.4
Patch foraging total patch changes 6 sec	2.1	3.2	4.7	-2.0	2.2	1.0
Patch foraging time to switch 0 sec	10.5	16.3	19.0	4.1	-4.4	-3.6
Patch foraging water rate 0 sec	17.8	28.5	33.1	-5.2	5.8	5.0
Patch foraging water rate 12 sec	10.7	16.4	18.8	-3.7	4.3	4.1
Patch foraging water rate 18 sec	5.2	7.0	7.3	-2.7	2.5	2.7
Patch foraging water rate 24 sec	4.2	5.8	6.4	-2.2	2.5	2.5
Patch foraging water rate 6 sec	5.2	7.6	9.0	-2.7	3.0	2.6
Seeking ratio, delayed vs. immediate footshock	0.2	0.3	0.6	-0.8	0.4	0.3
Distance traveled before self-admin	0.7	0.7	1.5	0.8	-0.1	-1.2
Distance traveled after self-admin	0.6	0.7	0.9	-0.7	1.0	0.7
Extensor digitorum longus weight	7.4	29.2	36.1	-6.0	5.1	5.1
Bone: elastic displacement	0.4	0.4	0.7	-0.5	0.6	0.8
Bone: elastic work	0.0	0.1	0.1	0.3	0.2	0.1
Bone: endosteal estimation	0.2	0.4	1.0	1.0	-0.4	-0.1
Bone: endosteal perimeter	0.1	0.1	0.3	0.5	0.3	-0.1
Epididymis fat weight	3.3	7.8	9.4	2.8	-3.1	-2.5
Delta time in closed arm before/after self-admin	0.1	0.1	0.1	-0.3	0.0	0.3
Delta time in open arm before/after self-admin	0.4	0.4	0.7	-0.9	0.5	0.5
Diff in mean of infusions in LGA sessions	0.0	0.0	0.1	0.1	0.0	-0.3
Delay discount exponential model param	0.1	0.1	0.1	-0.3	0.2	0.3
Extinction: sum of active levers before priming	0.1	0.1	0.2	0.2	-0.1	-0.4
Active lever presses in extinction session 6	1.6	1.6	1.7	-1.2	1.3	1.3
Bone: final force	0.1	0.2	0.5	0.0	0.7	0.4
Bone: final moment	0.2	0.3	0.5	-0.1	0.7	0.5
Food consumed during 24 hour testing period	0.6	0.7	1.2	-1.1	0.6	0.8
Glucose	0.4	0.6	1.0	-0.5	1.0	0.7
Heart weight	0.0	0.0	0.0	0.2	0.1	-0.1
Delay discount hyperbolic model param	0.1	0.1	0.2	-0.4	0.4	0.4
Intermittent access intake day 1-15 change	1.1	1.1	1.6	1.2	-1.0	-0.8
Intermittent access intake escalation	1.0	1.0	1.6	1.2	-1.1	-0.5
Intermittent access intake escalation 2	0.2	0.2	0.3	0.5	-0.3	-0.4
Intermitt. access day 1 inactive lever presses	2.4	2.6	3.3	-1.8	1.7	1.3
Intermitt. access day 15 inactive lever presses	1.2	1.3	1.7	-1.0	1.2	1.3
Intermitt. access escalation Index	0.2	0.2	0.2	-0.4	0.5	0.4
Intermittent access day 1 total infusions	0.1	0.1	0.1	0.2	-0.3	-0.3
Intermittent access day 15 total infusions	0.9	1.0	1.5	1.2	-1.1	-0.6
Intermittent access terminal intake (last 3 days)	1.2	1.3	1.7	1.3	-1.2	-1.0
Intermittent access total infusions	0.2	0.2	0.3	0.6	-0.5	-0.3
Intermittent access day 1 locomotion	0.3	0.3	0.4	0.5	-0.6	-0.6
Intermittent access day 15 total locomotion	0.0	0.0	0.1	0.3	-0.1	0.2
Intermittent access total locomotion	0.0	0.1	0.1	0.2	-0.3	-0.1
Intermittent access standard deviation	2.3	2.4	2.7	1.5	-1.6	-1.5
Left kidney weight	1.7	4.8	6.1	-2.5	1.7	2.3
Right kidney weight	1.1	3.1	3.8	-1.9	1.3	1.9
Cocaine induced anxiety	1.4	1.7	3.2	-1.0	1.8	0.9
Post-drug Anxiety	1.2	1.3	2.8	-0.8	1.7	0.7
Baseline Anxiety	1.2	1.2	1.6	1.1	-1.3	-0.9
Tail length	5.3	16.1	17.1	-4.1	3.8	4.1
Length with tail	6.8	24.7	31.4	-5.6	4.5	4.7
Length without tail	2.5	5.4	9.4	-3.1	2.0	1.7
Times rat made contact with spout	0.2	0.2	0.4	-0.5	0.6	-0.0
Lifetime Intake	0.0	0.0	0.1	0.4	-0.1	0.0
Liver weight, left	2.5	4.0	5.2	-1.8	2.3	1.8
Liver weight, right	0.1	0.2	0.4	-0.6	0.2	-0.3
Locomotor activity	0.1	0.1	0.3	-0.5	0.3	-0.1
Locomotor testing distance	0.2	0.3	0.4	-0.6	0.6	0.1
Locomotor testing rearing	2.3	3.6	5.2	1.8	-1.5	-2.3
Locomotion in novel chamber	6.6	8.1	10.4	-2.5	2.8	3.2
Locomotion in novel chamber post-restriction	0.0	0.0	0.1	0.2	0.0	0.2
Fecal boli incidents, locomotor time 1	2.2	2.4	4.1	1.1	-2.0	-1.3
Change in fecal boli incidents, locomotor task	2.7	2.5	3.4	-1.5	1.8	1.4
Time >=10cm from walls, locomotor time 1	0.2	0.2	0.4	-0.3	-0.3	-0.6
Bouts of movement, locomotor time 1	2.0	2.2	4.3	1.2	-2.1	-0.9
Total resting periods, locomotor time 1	1.8	2.0	3.9	1.2	-2.0	-0.7
Rest time, locomotor task time 1	0.0	0.0	0.1	0.1	-0.0	0.3
Distance moved, locomotor task time 1	0.6	0.6	1.2	0.8	-0.1	-1.1
Vertical activity count, locomotor time 1	0.2	0.2	0.5	0.1	0.7	-0.2
Time >=10cm from walls, locomotor time 2	0.4	0.5	1.0	-1.0	0.3	0.5
Bouts of movement, locomotor time 2	1.2	1.3	1.4	-1.1	1.2	1.2
Total resting periods, locomotor time 2	1.0	1.1	1.2	-0.9	1.1	1.1
Rest time, locomotor task time 2	0.2	0.2	0.6	-0.2	0.8	0.3
Distance moved, locomotor task time 2	0.7	0.8	1.0	0.8	-0.8	-1.0
Vertical activity count, locomotor time 2	0.0	0.0	0.1	-0.1	0.0	-0.3
Light reinforcement 1	0.0	0.0	0.0	0.0	0.0	0.1
Light reinforcement 2	2.0	2.6	3.2	1.6	-1.4	-1.8
Bone: marrow area	0.2	0.4	1.0	1.0	-0.3	-0.1
Bone: maximum diameter	0.1	0.2	0.2	0.5	0.2	-0.4
Bone: maximum force	0.1	0.2	0.5	-0.1	0.7	0.3
Bone: maximum moment	0.1	0.2	0.4	-0.2	0.6	0.4
Mean time between licks in bursts	0.4	0.6	0.9	0.9	-0.7	-0.7
Mean num. licks in bursts	0.3	0.3	0.8	-0.9	0.4	0.2
Cd content in liver	1.5	1.7	2.5	-1.3	1.0	1.6
Co content in liver	1.4	1.6	2.0	-1.4	1.2	1.2
Cu content in liver	1.9	2.4	3.1	1.7	-1.1	-1.7
Fe content in liver	0.7	0.8	1.2	1.1	-0.7	-0.9
K content in liver	0.2	0.2	0.4	-0.6	0.4	0.3
Mg content in liver	0.3	0.3	0.5	-0.3	0.7	0.4
Mn content in liver	0.5	0.6	1.1	-0.6	0.6	1.0
Na content in liver	0.3	0.3	0.5	0.5	-0.5	-0.7
Rb content in liver	0.9	1.1	1.2	-1.0	1.1	1.0
Se content in liver	0.0	0.0	0.1	0.2	-0.3	-0.1
Sr content in liver	0.3	0.2	0.4	-0.3	0.6	0.5
Zn content in liver	0.2	0.2	0.4	-0.3	0.6	0.4
Bone: minimum diameter	0.9	1.7	2.1	-1.1	1.5	1.3
Time in familiar zone, hab. session 1	0.2	0.1	0.4	0.0	-0.6	-0.2
Time in novel zone, hab. session 1	0.3	0.3	0.5	0.7	-0.4	-0.4
Total zone transitions, hab. session 1	0.2	0.3	0.6	0.6	-0.8	-0.3
Total locomotion distance, hab. session 1	0.4	0.5	1.1	-0.5	0.5	1.0
Locomotion velocity, hab. session 1	0.9	1.3	1.7	-0.9	1.1	1.3
Time in familiar zone, hab. session 2	0.3	0.3	0.4	-0.2	-0.7	-0.6
Time in novel zone, hab. session 2	0.2	0.2	0.5	0.7	-0.0	-0.0
Total zone transitions, hab. session 2	0.5	0.6	1.1	0.6	-1.0	-0.6
Total locomotion distance, hab. session 2	0.5	0.6	1.1	-0.6	0.7	1.0
Locomotion velocity, hab. session 2	0.7	0.9	1.4	-0.8	0.9	1.2
Novel to familiar place preference ratio	0.6	0.6	0.8	0.7	-0.9	-0.7
Novelty place preference	0.4	0.4	0.5	0.7	-0.7	-0.5
Time in novel zone, NPP test	0.2	0.2	0.4	0.4	-0.6	-0.3
Total zone transitions, NPP test	0.3	0.4	0.7	-0.8	-0.3	0.6
Total locomotion distance, NPP test	0.3	0.5	0.7	-0.8	0.2	0.8
Locomotion velocity, NPP test	0.3	0.4	0.7	-0.7	0.4	0.9
Intraocular pressure	0.1	0.1	0.2	-0.0	-0.5	-0.4
Delta distance traveled before/after self-admin	0.7	0.8	1.6	-0.8	0.3	1.3
Delta ambulatory time before/after self-admin	2.0	2.2	3.7	-1.5	0.9	1.9
Parametrial fat weight	0.0	0.1	0.1	0.3	-0.0	-0.2
Pavlov. Cond. lever latency	0.6	0.8	0.9	-0.6	0.9	1.0
Pavlov. Cond. magazine entry latency	0.6	0.8	1.4	0.5	-1.2	-0.8
Pavlov. Cond. change in total contacts	0.2	0.2	0.3	0.3	-0.6	-0.4
Pavlov. Cond. index score	0.9	1.1	1.9	0.7	-1.4	-1.0
Pavlov. Cond. latency score	0.7	0.8	1.3	0.6	-1.1	-0.9
Pavlov. Cond. lever contacts	1.1	1.3	1.5	1.0	-1.2	-1.2
Pavlov. Cond. magazine entry number	0.7	0.9	1.5	-0.5	1.2	0.9
Pavlov. Cond. intertrial magazine entries	6.9	8.3	10.4	-3.2	2.9	2.5
Pavlov. Cond. lever-magazine prob. diff.	0.7	0.9	1.5	0.6	-1.2	-0.9
Pavlov. Cond. response bias	0.8	1.0	1.6	0.6	-1.3	-1.0
Pavlov. Cond. lever latency	1.5	2.1	3.5	-1.9	1.3	1.0
Pavlov. Cond. magazine entry latency	3.5	4.1	4.7	2.2	-2.1	-1.8
Pavlov. Cond. change in total contacts	4.1	5.6	7.6	2.7	-2.1	-2.2
Pavlov. Cond. index score	3.5	4.5	5.9	2.4	-2.1	-1.8
Pavlov. Cond. latency score	3.7	4.6	5.8	2.4	-2.1	-1.9
Pavlov. Cond. lever contacts	2.1	2.9	4.3	2.1	-1.6	-1.4
Pavlov. Cond. magazine entry number	2.6	3.1	3.8	-2.0	1.8	1.6
Pavlov. Cond. intertrial magazine entries	5.5	7.1	7.4	-2.7	2.7	2.6
Pavlov. Cond. lever-magazine prob. diff.	4.1	5.2	6.9	2.6	-2.2	-2.0
Pavlov. Cond. response bias	2.3	3.1	4.4	2.1	-1.8	-1.4
Time in closed arm before self-admin	5.4	6.1	7.6	2.8	-2.1	-2.6
Time in closed arm after self-admin	1.9	1.9	2.8	1.7	-1.3	-1.1
Time in open arm before self-admin	7.5	8.1	8.8	-2.7	3.0	2.9
Time in open arm after self-admin	4.8	5.3	7.4	-2.7	2.2	1.9
Bone: periosteal estimation	0.1	0.2	0.3	0.3	0.6	0.4
Bone: periosteal perimeter	0.1	0.1	0.3	0.2	0.5	-0.0
Bone: post-yield work	1.4	1.9	2.5	-1.6	1.2	1.3
Progressive ratio test 1 active lever presses	0.0	0.0	0.0	-0.0	0.1	0.1
Progressive ratio test 1 breakpoint	0.0	0.0	0.0	0.1	-0.0	-0.1
Progressive ratio test 1 inactive lever presses	2.8	3.0	3.9	-2.0	1.7	1.5
Progressive ratio test 2 active lever presses	0.1	0.1	0.2	0.1	0.2	0.4
Progressive ratio test 2 breakpoint	0.1	0.1	0.3	-0.0	0.3	0.6
Progressive ratio test 2 inactive lever presses	1.2	1.4	2.3	-0.6	1.2	1.5
Incentive Sensitization - Responses	0.1	0.1	0.2	0.2	0.0	0.5
Incentive Sensitization - Breakpoint	0.1	0.1	0.4	0.0	0.2	0.6
Sum of active levers in priming session hrs 5-6	0.4	0.4	0.6	0.8	-0.3	-0.7
Progressive ratio	0.7	0.8	1.6	0.1	1.2	0.9
Food seeking constrained by brief footshock	0.5	0.6	0.7	-0.8	0.9	0.7
Seeking ratio, punishment vs. effort	0.2	0.2	0.3	-0.5	-0.4	-0.3
Retroperitoneal fat weight	0.1	0.5	0.8	0.5	-0.9	-0.6
Reaction time number correct	3.3	4.8	6.0	-2.4	2.0	2.1
Reaction time mean minus median	0.2	0.2	0.6	0.1	-0.8	-0.2
Reaction time mean minus median AUC	0.1	0.2	0.5	-0.2	-0.7	0.1
Reaction time num false alarms	1.3	1.8	2.5	-1.6	1.3	1.1
Reaction time num false alarms AUC	1.7	2.4	3.0	-1.7	1.5	1.3
Reaction time trials correct on left	3.3	4.8	6.0	-2.4	2.0	2.1
Reaction time trials on left	3.4	4.9	6.1	-2.5	2.0	2.1
Reaction time mean	0.8	1.1	1.8	1.1	-1.3	-0.5
Reaction time mean AUC	0.4	0.6	1.2	0.7	-1.1	-0.3
Median of all reaction times	0.4	0.5	0.7	0.9	-0.9	-0.2
Reaction time omissions	1.6	2.3	3.4	-1.7	0.7	1.8
Reaction time false alarm rate	0.1	0.2	0.3	-0.5	0.5	0.2
Reaction time premature initiation rate	0.7	0.9	1.6	-0.6	1.3	0.8
Reaction time premature initiations	2.4	3.4	4.3	-1.7	2.1	1.7
Std. dev. reaction times	0.4	0.5	1.1	0.7	-1.1	-0.3
Reaction time trials completed	3.4	4.9	6.1	-2.5	2.0	2.1
Reaction time trials AUC	3.6	5.1	6.2	-2.5	2.1	2.2
Run reversals in cocaine runway, females	1.6	1.5	2.6	1.3	-1.6	-0.4
Run reversals in cocaine runway, males	0.2	0.2	0.5	-0.1	0.7	0.2
Latency to leave start box in cocaine runway	0.2	0.2	0.5	0.4	-0.2	-0.7
Latency to leave start box in cocaine runway, F	0.4	0.4	0.7	0.6	-0.5	-0.9
Latency to leave start box in cocaine runway, M	0.2	0.2	0.3	0.3	-0.0	-0.6
Std. dev. time between licks in bursts	0.1	0.1	0.2	-0.2	-0.5	0.2
Total sessions with >9 infusions	0.1	0.1	0.1	0.1	0.3	0.3
Short access day 1 total inactive lever presses	0.0	0.1	0.1	-0.2	0.2	0.3
Short access day 10 total inactive lever presses	0.7	0.8	1.0	-0.9	0.6	1.0
Short access day 1 total infusions	0.5	0.6	1.0	-0.4	1.0	0.8
Short access day 10 total infusions	0.1	0.1	0.3	0.5	-0.1	-0.2
Short access total infusions	0.1	0.1	0.3	0.6	0.1	-0.0
Short access day 1 locomotion	0.2	0.3	0.4	0.5	-0.3	-0.6
Short access day 10 total locomotion	0.4	0.4	0.6	0.5	-0.6	-0.8
Short access total locomotion	0.0	0.0	0.0	0.1	0.1	-0.1
One hour access (0.3 mA shock)	0.2	0.3	0.5	-0.5	0.7	0.4
Compulsive drug intake	0.2	0.2	0.5	-0.4	-0.4	-0.7
One hour access (shock baseline)	0.0	0.1	0.1	0.2	0.2	0.3
Social response proportion	0.3	0.3	0.8	0.1	0.9	0.3
Social responses	0.1	0.1	0.1	0.4	-0.0	-0.3
Social time	1.5	2.0	3.1	-1.1	1.3	1.8
Soleus weight	0.4	1.0	2.9	-1.7	0.1	0.5
Bone: stiffness	1.2	1.9	2.8	-1.2	1.7	1.2
Tibialis anterior weight	0.4	1.4	2.3	-1.5	1.2	0.8
Time to tail flick, vehicle, before self-admin	0.9	1.0	1.6	-1.3	0.7	0.9
Time to tail flick, vehicle, after self-admin	0.1	0.2	0.3	-0.5	-0.4	0.1
Time to tail flick, test, before self-admin	0.1	0.1	0.1	-0.2	0.4	-0.0
Time to tail flick, test, after self-admin	2.0	2.1	2.4	-1.6	1.2	1.5
Delta time to tail flick, vehicle, before/after SA	0.0	0.0	0.1	-0.1	-0.3	0.0
Delta time to tail flick, test, before/after SA	1.7	1.6	2.2	-1.5	0.9	1.3
Tibia length	0.1	0.3	0.4	-0.3	0.7	0.5
Ambulatory time before self-admin	0.9	1.0	1.6	1.1	-0.4	-1.3
Ambulatory time after self-admin	0.0	0.0	0.0	0.1	0.1	-0.1
Bone: tissue strength	0.0	0.0	0.1	0.4	-0.1	-0.1
Total heroin consumption	0.8	0.9	1.2	-1.1	1.1	0.7
Bone: trabecular number	0.2	0.3	0.5	-0.7	0.2	0.7
Bone: trabecular spacing	0.0	0.0	0.1	0.3	-0.1	-0.1
Bone: trabecular thickness	0.0	0.0	0.1	-0.2	0.2	0.2
Bone: trabecular tissue density	0.0	0.0	0.1	-0.0	0.3	-0.1
Water consumed over 24 hours	2.8	3.4	4.7	-1.6	2.2	1.8
Number of responses in last shaping day	0.6	0.7	1.1	0.8	-0.5	-1.1