Hub : Genes

LOC120103628

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	BLA	gene expression	LOC120103628	0.13	0.1	3.3e-07	0.13	0.12	0.13	0.13	1.5e-07	3.4e-07	1.9e-07	2.4e-07
2	PL	gene expression	LOC120103628	0.28	0.18	6.7e-06	0.04	0.04	0.04	0.04	4.7e-05	2.9e-05	9.5e-05	8.3e-05
3	Brain	gene expression	LOC120103628	0.04	0.04	1.3e-03	0.02	0.03	0.01	0.02	4.9e-03	1.6e-03	2.5e-02	3.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Bone: apparent density	0.0	0.1	0.1	0.2	-0.3	-0.2
Area under the delay curve	0.0	0.0	0.1	0.0	0.1	-0.3
BMI with tail	2.3	7.3	8.2	2.8	-2.5	-2.9
BMI without tail	0.8	1.7	2.3	1.2	-1.5	-1.2
Body weight	0.1	0.5	0.7	-0.7	0.8	0.6
Weight adjusted by age	0.0	0.0	0.0	-0.2	0.1	0.1
Bone surface	0.1	0.2	0.4	0.3	-0.6	-0.2
Bone volume	0.1	0.1	0.3	0.3	-0.5	-0.2
Breakpoint value in progressive ratio session	0.0	0.1	0.1	0.3	-0.3	-0.1
Number of licking bursts	0.0	0.0	0.1	-0.2	-0.0	0.3
Context. condit. distance diff. score	1.7	2.0	2.2	-1.4	1.4	1.5
Locomotion velocity, session 1	0.1	0.1	0.3	-0.4	0.0	0.5
Locomotion distance, session 1	0.5	0.7	0.9	0.8	-1.0	-0.7
Locomotion velocity, session 2	0.1	0.1	0.4	-0.1	0.6	-0.0
Locomotion distance, session 2	0.4	0.5	0.7	0.7	-0.8	-0.6
Locomotion velocity, session 3	0.1	0.1	0.2	0.4	-0.1	-0.4
Locomotion distance, session 3	0.0	0.0	0.0	-0.0	-0.1	0.1
Stereotopy head waving bouts, day 3	0.2	0.2	0.2	-0.4	0.4	0.4
Stereotopy head waving duration, day 3	0.3	0.3	0.4	-0.6	0.6	0.5
Locomotion velocity, session 7	0.1	0.2	0.3	0.5	0.0	-0.5
Locomotion distance, session 7	0.7	0.9	1.1	1.0	-0.8	-1.0
Stereotopy head waving bouts, day 7	1.2	1.3	1.5	-1.2	1.2	1.1
Stereotopy head waving duration, day 7	0.5	0.6	0.8	-0.8	0.9	0.6
Locomotion velocity, session 8	0.3	0.3	0.4	-0.5	0.6	0.5
Locomotion distance, session 8	0.1	0.1	0.1	0.3	-0.4	-0.1
Degree of sensitization distance	0.1	0.1	0.1	0.3	-0.1	-0.3
Degree of sensitization stereotypy	0.2	0.2	0.2	-0.5	0.4	0.5
Conditioned locomotion	1.4	1.6	1.9	-1.3	1.4	1.2
Cocaine response after cond. corrected	0.6	0.7	0.8	0.9	-0.9	-0.8
Cocaine response after cond. not corrected	1.9	2.1	2.2	1.5	-1.4	-1.4
Cocaine response before conditioning	2.1	2.5	3.0	1.6	-1.4	-1.7
Saline control response	0.2	0.3	0.4	0.5	-0.6	-0.5
Bone: connectivity density	0.1	0.1	0.1	-0.3	0.3	0.2
Bone: cortical apparent density	9.2	12.1	12.7	-3.4	3.6	3.4
Bone: cortical area	0.6	0.9	1.6	-1.0	0.3	1.3
Bone: cortical porosity	0.0	0.0	0.0	-0.0	0.1	0.0
Bone: cortical porosity	0.3	0.3	0.3	0.5	-0.6	-0.5
Bone: cortical thickness	0.6	1.0	1.7	-1.1	0.4	1.3
Bone: cortical thickness	0.5	0.6	1.0	-0.9	0.3	1.0
Bone: cortical tissue density	9.3	12.2	12.9	-3.5	3.6	3.4
Condit. Reinf. active minus inactive responses	0.6	0.6	0.7	0.8	-0.8	-0.8
Condit. Reinf. active-inactive response ratio	2.7	2.9	3.0	1.7	-1.7	-1.7
Condit. Reinf. active responses	0.1	0.1	0.2	0.4	-0.3	-0.4
Condit. Reinf. inactive responses	1.8	2.2	2.2	-1.4	1.5	1.5
Incentive salience index mean	0.5	0.6	0.7	0.8	-0.8	-0.7
Condit. Reinf. lever presses	0.1	0.1	0.1	0.3	-0.2	-0.3
Condit. Reinf. active minus inactive responses	0.4	0.6	0.7	-0.7	0.8	0.7
Condit. Reinf. active-inactive response ratio	0.5	0.5	0.6	-0.7	0.7	0.7
Condit. Reinf. active responses	0.0	0.0	0.1	-0.1	0.3	-0.1
Condit. Reinf. inactive responses	0.5	0.7	0.8	0.8	-0.7	-0.9
Condit. Reinf. lever presses	1.6	2.1	2.4	1.5	-1.3	-1.5
Condit. Reinf. lever reinforcers received	0.0	0.0	0.1	-0.0	0.3	-0.1
Conditioned reinforcement - actives	2.2	2.2	2.3	-1.5	1.5	1.5
Conditioned reinforcement - inactives	0.3	0.4	0.4	-0.6	0.6	0.6
Conditioned locomotion	0.6	0.8	0.9	0.9	-0.8	-0.9
Patch foraging indifference point 0 sec	4.4	7.0	8.8	-2.6	3.0	2.4
Patch foraging indifference point AUC	3.0	3.5	3.7	-1.9	1.9	1.8
Delay disc. indifference point, 0s delay	0.2	0.2	0.4	-0.4	0.6	0.3
Delay disc. indifference point, 16s delay	0.0	0.0	0.0	0.0	0.2	-0.2
Delay disc. indifference point, 2s delay	0.1	0.1	0.1	0.2	-0.3	-0.2
Delay disc. indifference point, 24s delay	0.1	0.1	0.2	0.2	-0.5	-0.2
Delay disc. indifference point, 4s delay	0.3	0.4	0.7	-0.6	0.8	0.3
Delay disc. indifference point, 8s delay	0.1	0.1	0.2	0.2	0.1	-0.5
Indifference point function ln k	0.4	0.5	0.7	-0.8	0.6	0.8
Indifference point function log k	0.4	0.5	0.7	-0.8	0.6	0.8
Patch foraging total patch changes 0 sec	5.0	8.0	10.3	-2.7	3.2	2.5
Patch foraging total patch changes 12 sec	4.9	6.4	8.5	-2.4	2.9	2.2
Patch foraging total patch changes 18 sec	2.7	3.5	5.7	-1.6	2.4	1.4
Patch foraging total patch changes 24 sec	0.5	0.6	1.1	-0.6	1.0	0.5
Patch foraging total patch changes 6 sec	2.9	4.3	5.9	-2.0	2.4	1.8
Patch foraging time to switch 0 sec	11.5	17.7	19.1	4.4	-4.1	-4.2
Patch foraging water rate 0 sec	20.4	32.8	34.5	-5.9	5.7	5.6
Patch foraging water rate 12 sec	9.4	14.4	15.7	-4.0	3.6	3.8
Patch foraging water rate 18 sec	4.8	6.5	7.1	-2.7	2.3	2.6
Patch foraging water rate 24 sec	3.6	5.0	5.9	-2.4	1.9	2.4
Patch foraging water rate 6 sec	4.9	7.2	7.6	-2.8	2.7	2.6
Seeking ratio, delayed vs. immediate footshock	0.2	0.2	0.3	-0.5	0.3	0.5
Distance traveled before self-admin	0.0	0.0	0.0	0.1	-0.1	-0.1
Distance traveled after self-admin	0.4	0.4	0.6	-0.8	0.5	0.7
Extensor digitorum longus weight	5.5	21.5	23.2	-4.8	4.3	4.8
Bone: elastic displacement	0.5	0.5	0.7	-0.8	0.5	0.8
Bone: elastic work	0.1	0.1	0.2	-0.3	-0.2	0.4
Bone: endosteal estimation	0.3	0.6	0.9	0.8	-0.9	-0.7
Bone: endosteal perimeter	0.1	0.2	0.5	0.2	-0.7	-0.1
Epididymis fat weight	4.2	9.8	10.7	3.2	-2.9	-3.3
Delta time in closed arm before/after self-admin	0.1	0.1	0.1	0.3	-0.3	-0.2
Delta time in open arm before/after self-admin	0.5	0.4	0.5	-0.6	0.7	0.7
Diff in mean of infusions in LGA sessions	0.0	0.0	0.0	-0.1	0.1	0.2
Delay discount exponential model param	0.0	0.0	0.0	0.0	-0.1	0.2
Extinction: sum of active levers before priming	0.0	0.0	0.0	0.1	-0.1	-0.0
Active lever presses in extinction session 6	1.1	1.0	1.2	-1.0	0.9	1.1
Bone: final force	0.1	0.2	0.5	-0.5	-0.1	0.7
Bone: final moment	0.2	0.3	0.6	-0.5	-0.2	0.8
Food consumed during 24 hour testing period	0.1	0.1	0.1	-0.3	0.1	0.4
Glucose	1.1	1.6	1.9	-1.2	1.4	1.2
Heart weight	0.0	0.0	0.0	0.1	0.1	-0.1
Delay discount hyperbolic model param	0.0	0.0	0.1	-0.0	-0.1	0.3
Intermittent access intake day 1-15 change	1.3	1.3	1.3	1.2	-1.1	-1.1
Intermittent access intake escalation	1.5	1.5	1.6	1.3	-1.2	-1.2
Intermittent access intake escalation 2	0.2	0.2	0.3	0.4	-0.6	-0.3
Intermitt. access day 1 inactive lever presses	2.7	2.9	3.1	-1.8	1.6	1.7
Intermitt. access day 15 inactive lever presses	1.0	1.0	1.1	-1.0	1.0	1.0
Intermitt. access escalation Index	0.4	0.4	0.5	-0.6	0.7	0.5
Intermittent access day 1 total infusions	0.3	0.4	0.5	0.7	-0.5	-0.7
Intermittent access day 15 total infusions	1.7	1.9	2.1	1.4	-1.2	-1.4
Intermittent access terminal intake (last 3 days)	1.7	1.9	2.3	1.3	-1.2	-1.5
Intermittent access total infusions	0.6	0.6	0.8	0.8	-0.6	-0.9
Intermittent access day 1 locomotion	0.8	0.9	1.0	1.0	-0.8	-1.0
Intermittent access day 15 total locomotion	0.4	0.4	0.4	0.7	-0.6	-0.6
Intermittent access total locomotion	0.4	0.5	0.5	0.7	-0.6	-0.7
Intermittent access standard deviation	3.5	3.7	3.9	2.0	-1.8	-1.9
Left kidney weight	0.8	2.2	2.8	-1.4	1.7	1.3
Right kidney weight	0.3	0.9	1.3	-0.9	1.1	0.8
Cocaine induced anxiety	2.8	3.3	3.5	-1.9	1.7	1.9
Post-drug Anxiety	2.4	2.7	2.8	-1.7	1.5	1.7
Baseline Anxiety	1.5	1.6	1.7	1.3	-1.1	-1.3
Tail length	2.8	8.4	9.3	-3.0	2.6	3.1
Length with tail	4.3	15.6	16.2	-4.0	3.9	3.9
Length without tail	2.5	5.4	7.1	-2.2	2.7	2.1
Times rat made contact with spout	0.4	0.5	0.7	-0.7	0.8	0.6
Lifetime Intake	0.2	0.3	0.4	0.6	-0.4	-0.6
Liver weight, left	2.6	4.1	5.1	-2.1	1.6	2.3
Liver weight, right	0.0	0.0	0.0	-0.1	0.2	0.1
Locomotor activity	0.2	0.3	0.5	-0.4	0.7	0.3
Locomotor testing distance	0.5	0.9	1.4	-0.9	1.2	0.7
Locomotor testing rearing	0.7	1.1	1.9	1.1	-0.5	-1.4
Locomotion in novel chamber	5.2	6.4	7.0	-2.6	2.4	2.6
Locomotion in novel chamber post-restriction	0.3	0.4	0.9	0.5	-0.9	-0.3
Fecal boli incidents, locomotor time 1	2.6	2.9	4.0	1.6	-2.0	-1.4
Change in fecal boli incidents, locomotor task	0.5	0.4	0.7	-0.6	0.9	0.4
Time >=10cm from walls, locomotor time 1	0.4	0.4	0.5	0.6	-0.7	-0.7
Bouts of movement, locomotor time 1	1.6	1.7	2.4	1.2	-1.5	-1.1
Total resting periods, locomotor time 1	1.5	1.7	2.2	1.2	-1.5	-1.1
Rest time, locomotor task time 1	0.1	0.1	0.2	-0.3	0.2	0.5
Distance moved, locomotor task time 1	0.1	0.1	0.3	0.3	0.0	-0.5
Vertical activity count, locomotor time 1	0.9	0.9	1.2	-1.0	1.1	0.8
Time >=10cm from walls, locomotor time 2	0.7	0.7	0.9	-1.0	0.8	0.8
Bouts of movement, locomotor time 2	1.5	1.6	2.2	-1.4	0.9	1.5
Total resting periods, locomotor time 2	1.1	1.2	1.6	-1.2	0.8	1.3
Rest time, locomotor task time 2	0.2	0.2	0.3	-0.5	0.1	0.6
Distance moved, locomotor task time 2	0.1	0.1	0.2	0.3	0.1	-0.4
Vertical activity count, locomotor time 2	0.6	0.6	0.7	-0.7	0.8	0.8
Light reinforcement 1	0.0	0.0	0.1	0.1	0.2	-0.1
Light reinforcement 2	2.3	3.1	4.2	1.7	-2.0	-1.5
Bone: marrow area	0.3	0.5	0.8	0.7	-0.9	-0.6
Bone: maximum diameter	0.1	0.1	0.2	-0.1	-0.4	0.3
Bone: maximum force	0.2	0.3	0.5	-0.5	0.0	0.7
Bone: maximum moment	0.1	0.2	0.5	-0.5	-0.2	0.7
Mean time between licks in bursts	1.0	1.4	1.4	1.2	-1.2	-1.2
Mean num. licks in bursts	0.1	0.1	0.2	-0.1	0.4	0.1
Cd content in liver	0.2	0.2	0.4	-0.5	0.1	0.6
Co content in liver	0.8	0.9	1.0	-1.0	0.9	1.0
Cu content in liver	1.1	1.3	1.3	1.1	-1.1	-1.1
Fe content in liver	0.1	0.1	0.1	0.3	-0.4	-0.3
K content in liver	0.2	0.2	0.3	-0.4	0.5	0.3
Mg content in liver	0.2	0.2	0.5	-0.4	0.7	0.3
Mn content in liver	0.1	0.1	0.2	-0.1	0.4	0.1
Na content in liver	0.0	0.0	0.0	0.1	-0.1	-0.1
Rb content in liver	1.0	1.2	1.7	-1.0	1.3	0.9
Se content in liver	0.4	0.4	1.0	0.5	-1.0	-0.3
Sr content in liver	0.2	0.2	0.3	-0.4	-0.0	0.5
Zn content in liver	0.1	0.1	0.2	-0.4	0.2	0.5
Bone: minimum diameter	0.5	1.0	1.2	-1.0	0.9	1.1
Time in familiar zone, hab. session 1	0.3	0.2	0.5	0.5	0.1	-0.7
Time in novel zone, hab. session 1	0.4	0.4	0.9	0.4	-0.9	-0.3
Total zone transitions, hab. session 1	0.7	1.0	1.3	0.9	-1.1	-0.9
Total locomotion distance, hab. session 1	0.0	0.0	0.0	-0.2	0.1	0.1
Locomotion velocity, hab. session 1	0.4	0.6	0.6	-0.8	0.7	0.8
Time in familiar zone, hab. session 2	0.3	0.3	0.5	0.5	0.1	-0.7
Time in novel zone, hab. session 2	0.3	0.3	0.7	0.4	-0.8	-0.2
Total zone transitions, hab. session 2	1.0	1.2	1.7	1.1	-1.3	-0.9
Total locomotion distance, hab. session 2	0.2	0.3	0.5	-0.6	0.3	0.7
Locomotion velocity, hab. session 2	0.4	0.5	0.8	-0.8	0.5	0.9
Novel to familiar place preference ratio	0.6	0.6	0.9	0.7	-0.9	-0.6
Novelty place preference	0.3	0.3	0.5	0.5	-0.7	-0.5
Time in novel zone, NPP test	0.3	0.3	0.5	0.5	-0.7	-0.4
Total zone transitions, NPP test	0.3	0.4	0.7	0.5	-0.8	-0.4
Total locomotion distance, NPP test	0.0	0.1	0.2	-0.0	-0.4	0.2
Locomotion velocity, NPP test	0.0	0.1	0.1	-0.1	-0.3	0.2
Intraocular pressure	0.1	0.1	0.1	0.2	-0.3	-0.3
Delta distance traveled before/after self-admin	0.0	0.0	0.0	-0.1	-0.1	0.1
Delta ambulatory time before/after self-admin	0.4	0.4	0.5	-0.7	0.5	0.7
Parametrial fat weight	0.0	0.1	0.1	0.2	-0.4	-0.0
Pavlov. Cond. lever latency	0.6	0.8	0.9	-0.9	0.9	0.9
Pavlov. Cond. magazine entry latency	0.4	0.5	0.6	0.8	-0.6	-0.8
Pavlov. Cond. change in total contacts	0.2	0.2	0.3	0.5	-0.1	-0.5
Pavlov. Cond. index score	1.0	1.3	1.3	1.1	-1.2	-1.1
Pavlov. Cond. latency score	0.6	0.8	0.9	0.9	-0.9	-0.9
Pavlov. Cond. lever contacts	0.8	0.9	1.0	1.0	-0.9	-1.0
Pavlov. Cond. magazine entry number	1.1	1.4	1.5	-1.2	1.1	1.2
Pavlov. Cond. intertrial magazine entries	5.4	6.5	6.7	-2.6	2.5	2.6
Pavlov. Cond. lever-magazine prob. diff.	0.8	1.0	1.2	1.0	-1.1	-0.9
Pavlov. Cond. response bias	1.2	1.5	1.5	1.2	-1.2	-1.2
Pavlov. Cond. lever latency	2.5	3.3	3.5	-1.9	1.8	1.8
Pavlov. Cond. magazine entry latency	5.0	5.8	6.1	2.5	-2.3	-2.5
Pavlov. Cond. change in total contacts	3.8	5.3	5.9	2.4	-2.0	-2.4
Pavlov. Cond. index score	5.1	6.6	7.1	2.7	-2.4	-2.6
Pavlov. Cond. latency score	5.0	6.2	6.7	2.6	-2.3	-2.6
Pavlov. Cond. lever contacts	3.5	4.8	5.0	2.2	-2.2	-2.1
Pavlov. Cond. magazine entry number	3.6	4.4	5.1	-2.2	1.8	2.3
Pavlov. Cond. intertrial magazine entries	6.2	8.0	9.1	-2.8	3.0	2.7
Pavlov. Cond. lever-magazine prob. diff.	5.5	7.0	7.7	2.8	-2.4	-2.8
Pavlov. Cond. response bias	4.2	5.7	6.2	2.5	-2.3	-2.4
Time in closed arm before self-admin	3.1	3.5	3.6	1.8	-1.9	-1.9
Time in closed arm after self-admin	1.6	1.6	1.8	1.3	-1.2	-1.3
Time in open arm before self-admin	5.4	5.8	5.9	-2.4	2.4	2.4
Time in open arm after self-admin	3.5	3.9	4.2	-1.9	2.1	1.9
Bone: periosteal estimation	0.1	0.1	0.2	-0.2	-0.4	0.4
Bone: periosteal perimeter	0.1	0.1	0.3	-0.1	-0.5	0.3
Bone: post-yield work	1.1	1.6	1.6	-1.3	1.2	1.3
Progressive ratio test 1 active lever presses	0.0	0.0	0.0	0.1	0.1	-0.1
Progressive ratio test 1 breakpoint	0.1	0.1	0.1	0.2	-0.1	-0.3
Progressive ratio test 1 inactive lever presses	2.8	3.0	3.2	-1.8	1.7	1.8
Progressive ratio test 2 active lever presses	0.0	0.0	0.0	0.0	0.1	-0.1
Progressive ratio test 2 breakpoint	0.0	0.0	0.0	0.0	0.2	-0.1
Progressive ratio test 2 inactive lever presses	1.0	1.2	1.4	-1.1	1.2	1.0
Incentive Sensitization - Responses	0.0	0.0	0.0	0.1	-0.0	-0.1
Incentive Sensitization - Breakpoint	0.0	0.0	0.0	-0.0	0.1	-0.0
Sum of active levers in priming session hrs 5-6	0.2	0.2	0.2	0.5	-0.4	-0.4
Progressive ratio	0.3	0.4	0.5	-0.6	0.5	0.7
Food seeking constrained by brief footshock	1.4	1.8	2.3	-1.4	1.0	1.5
Seeking ratio, punishment vs. effort	0.1	0.1	0.1	-0.4	0.2	0.3
Retroperitoneal fat weight	0.3	0.9	1.1	1.0	-1.0	-0.9
Reaction time number correct	3.9	5.6	7.0	-2.3	2.6	2.1
Reaction time mean minus median	0.3	0.4	0.6	0.6	-0.8	-0.5
Reaction time mean minus median AUC	0.3	0.4	0.7	0.6	-0.8	-0.4
Reaction time num false alarms	1.3	1.7	2.4	-1.3	1.5	1.1
Reaction time num false alarms AUC	1.6	2.3	2.7	-1.5	1.6	1.4
Reaction time trials correct on left	3.9	5.6	7.0	-2.3	2.6	2.1
Reaction time trials on left	3.8	5.5	6.8	-2.3	2.6	2.1
Reaction time mean	1.2	1.6	1.8	1.3	-1.3	-1.2
Reaction time mean AUC	0.9	1.2	1.3	1.1	-1.1	-1.0
Median of all reaction times	0.7	0.9	1.1	1.1	-0.9	-0.9
Reaction time omissions	0.6	0.8	1.1	-0.9	0.7	1.1
Reaction time false alarm rate	0.1	0.1	0.1	-0.4	0.3	0.3
Reaction time premature initiation rate	0.9	1.1	1.4	-1.0	1.2	1.0
Reaction time premature initiations	3.0	4.2	5.1	-2.0	2.3	1.9
Std. dev. reaction times	0.8	1.1	1.7	1.0	-1.3	-0.8
Reaction time trials completed	3.8	5.5	6.8	-2.3	2.6	2.1
Reaction time trials AUC	4.2	6.1	7.7	-2.4	2.8	2.2
Run reversals in cocaine runway, females	1.0	0.9	1.1	1.0	-0.8	-1.1
Run reversals in cocaine runway, males	0.9	0.9	0.9	-0.9	0.9	1.0
Latency to leave start box in cocaine runway	0.1	0.1	0.1	0.1	0.3	-0.3
Latency to leave start box in cocaine runway, F	0.1	0.1	0.2	0.1	0.4	-0.3
Latency to leave start box in cocaine runway, M	0.1	0.1	0.1	0.2	-0.2	-0.3
Std. dev. time between licks in bursts	0.9	1.1	1.3	1.0	-1.2	-0.9
Total sessions with >9 infusions	0.0	0.0	0.0	0.1	0.1	-0.2
Short access day 1 total inactive lever presses	0.0	0.0	0.0	0.2	0.0	-0.2
Short access day 10 total inactive lever presses	0.4	0.4	0.4	-0.6	0.6	0.6
Short access day 1 total infusions	0.3	0.3	0.5	-0.5	0.7	0.5
Short access day 10 total infusions	0.3	0.3	0.5	0.6	-0.3	-0.7
Short access total infusions	0.1	0.2	0.2	0.4	-0.2	-0.5
Short access day 1 locomotion	0.5	0.5	0.7	0.7	-0.4	-0.9
Short access day 10 total locomotion	0.5	0.6	0.7	0.8	-0.6	-0.8
Short access total locomotion	0.0	0.0	0.1	0.2	0.0	-0.3
One hour access (0.3 mA shock)	0.1	0.1	0.2	-0.3	0.4	0.3
Compulsive drug intake	0.0	0.0	0.1	0.2	-0.2	-0.1
One hour access (shock baseline)	0.0	0.0	0.0	0.1	-0.1	-0.1
Social response proportion	0.5	0.6	0.9	-0.7	0.9	0.6
Social responses	0.0	0.0	0.0	0.1	-0.0	-0.2
Social time	0.7	0.9	1.0	-1.0	0.9	1.0
Soleus weight	0.0	0.0	0.0	0.1	-0.1	-0.2
Bone: stiffness	1.1	1.7	2.5	-1.4	0.8	1.6
Tibialis anterior weight	0.3	1.0	1.1	-1.1	0.9	1.0
Time to tail flick, vehicle, before self-admin	0.4	0.4	0.6	-0.7	0.5	0.8
Time to tail flick, vehicle, after self-admin	0.1	0.1	0.2	0.3	-0.2	-0.4
Time to tail flick, test, before self-admin	0.1	0.1	0.2	-0.3	0.4	0.3
Time to tail flick, test, after self-admin	1.6	1.7	1.8	-1.3	1.3	1.3
Delta time to tail flick, vehicle, before/after SA	0.0	0.0	0.1	0.1	0.1	-0.3
Delta time to tail flick, test, before/after SA	0.7	0.7	0.9	-0.8	0.6	0.9
Tibia length	0.3	0.7	1.2	-0.9	0.4	1.1
Ambulatory time before self-admin	0.0	0.0	0.1	0.2	-0.1	-0.2
Ambulatory time after self-admin	0.0	0.0	0.0	0.1	-0.2	-0.1
Bone: tissue strength	0.1	0.1	0.1	-0.2	-0.2	0.3
Total heroin consumption	0.9	1.0	1.4	-1.0	0.8	1.2
Bone: trabecular number	0.1	0.1	0.2	-0.3	0.5	0.2
Bone: trabecular spacing	0.2	0.2	0.5	0.3	-0.7	-0.2
Bone: trabecular thickness	0.1	0.1	0.1	-0.4	0.3	0.4
Bone: trabecular tissue density	0.5	0.7	1.3	-0.7	1.2	0.6
Water consumed over 24 hours	3.3	3.9	3.9	-2.0	2.0	2.0
Number of responses in last shaping day	0.8	0.8	1.1	0.9	-1.0	-0.7