Hub : Genes

LOC120103533

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability LOC120103533 0.03 0.02 2.1e-03 0.01 0.01 0.01 0.01 1.6e-02 2.0e-02 1.0e-02 2.4e-02
2 pVTA intron excision ratio chr6_68860402_68861662 0.26 0.12 2.1e-09 0.22 0.23 0.24 0.23 6.5e-10 2.6e-10 1.0e-10 3.1e-10
3 pVTA intron excision ratio chr6_68860402_68861600 0.25 0.12 1.4e-08 0.22 0.21 0.22 0.21 7.5e-10 2.0e-09 5.0e-10 2.0e-09
4 RMTg mRNA stability LOC120103533 0.17 0.1 3.4e-04 0.1 0.14 0.12 0.12 1.4e-03 1.2e-04 3.3e-04 5.2e-04
5 NAcc gene expression LOC120103533 0.48 0.13 0.0e+00 0.48 0.5 0.5 0.49 2.4e-62 1.4e-65 4.2e-66 6.8e-65
6 pVTA gene expression LOC120103533 0.19 0.1 3.2e-07 0.12 0.15 0.15 0.14 5.3e-06 5.0e-07 4.0e-07 9.4e-07
7 BLA mRNA stability LOC120103533 0.2 0.1 3.5e-09 0.16 0.16 0.16 0.15 1.1e-08 3.8e-09 1.0e-08 2.5e-08
8 Adipose mRNA stability LOC120103533 0.28 0.21 1.9e-08 0.08 0.08 0.09 0.08 4.1e-09 3.4e-09 1.2e-09 4.7e-09
9 Brain mRNA stability LOC120103533 0.27 0.12 0.0e+00 0.18 0.2 0.19 0.19 1.6e-16 8.8e-19 9.4e-18 1.6e-17
10 BLA gene expression LOC120103533 0.22 0.1 7.8e-10 0.19 0.16 0.16 0.17 2.0e-10 8.0e-09 6.6e-09 1.2e-09
11 Brain gene expression LOC120103533 0.38 0.15 0.0e+00 0.28 0.25 0.28 0.28 3.5e-26 4.9e-23 6.6e-26 8.0e-26
12 NAcc intron excision ratio chr6_68860402_68861662 0.31 0.11 0.0e+00 0.34 0.34 0.34 0.35 4.5e-40 2.3e-40 4.2e-41 8.1e-42
13 NAcc intron excision ratio chr6_68860402_68861600 0.37 0.11 0.0e+00 0.4 0.39 0.4 0.4 9.7e-50 2.3e-48 3.6e-50 5.5e-50
14 Brain intron excision ratio chr6_68860402_68861662 0.42 0.13 0.0e+00 0.36 0.38 0.38 0.38 4.8e-35 5.3e-37 1.2e-36 1.0e-37
15 Brain intron excision ratio chr6_68860402_68861600 0.58 0.12 0.0e+00 0.51 0.54 0.54 0.54 7.7e-55 2.4e-58 1.9e-59 1.9e-59
16 NAcc mRNA stability LOC120103533 0.23 0.1 0.0e+00 0.21 0.21 0.2 0.2 1.4e-23 2.1e-23 6.4e-23 3.2e-23
17 PL gene expression LOC120103533 0.15 0.08 8.1e-10 0.09 0.09 0.08 0.09 3.1e-10 6.3e-10 5.8e-09 6.0e-10
18 Liver gene expression LOC120103533 0.49 0.15 0.0e+00 0.33 0.34 0.33 0.33 5.7e-38 7.9e-39 4.7e-38 2.1e-37
19 Adipose gene expression LOC120103533 0.04 0.04 2.1e-03 0.01 0.02 0.03 0.02 1.3e-02 1.1e-03 6.8e-04 2.7e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.91.54.31.9-2.12.0-1.9-0.41.6-0.4-0.5-1.10.90.80.90.90.80.90.90.90.51.2
Area under the delay curve2.32.43.9-1.01.0-0.81.0-2.0-1.41.9-0.31.8-1.9-1.8-1.7-1.8-1.8-1.7-1.9-1.7-1.8-0.5
BMI with tail0.61.93.00.7-0.91.1-0.91.71.2-1.7-0.6-1.41.61.61.61.51.61.61.61.31.60.6
BMI without tail2.24.67.22.5-2.52.7-2.41.42.5-2.00.4-2.32.22.12.32.32.22.32.22.32.01.2
Body weight1.45.915.73.8-3.84.0-3.6-0.23.0-1.30.6-2.32.11.82.12.11.92.22.02.11.70.8
Weight adjusted by age0.20.20.6-0.50.1-0.0-0.00.80.0-0.7-0.6-0.30.30.60.40.40.50.40.50.40.4-0.1
Bone surface0.40.73.50.3-0.30.1-0.4-1.9-0.21.3-0.30.7-0.8-0.9-0.9-0.9-0.9-0.8-0.8-0.9-1.10.2
Bone volume0.30.52.21.1-1.21.0-1.1-1.50.60.7-0.80.0-0.2-0.3-0.2-0.2-0.3-0.2-0.2-0.2-0.60.8
Breakpoint value in progressive ratio session0.30.41.61.2-0.80.6-1.2-1.00.90.3-0.7-0.20.00.40.10.00.40.00.3-0.0-0.30.4
Number of licking bursts0.00.00.1-0.0-0.20.30.10.30.0-0.2-0.1-0.10.1-0.00.20.10.00.10.10.20.3-0.0
Context. condit. distance diff. score0.70.81.50.5-0.80.9-0.80.91.2-1.1-1.2-0.90.90.71.01.00.80.90.81.00.60.8
Locomotion velocity, session 10.20.21.20.00.4-0.50.1-0.5-0.10.5-0.10.3-0.4-0.5-0.4-0.4-0.5-0.4-0.4-0.4-0.6-1.1
Locomotion distance, session 10.30.31.1-0.81.0-1.01.10.8-0.7-0.20.80.2-0.1-0.2-0.1-0.1-0.2-0.1-0.1-0.00.20.7
Locomotion velocity, session 22.12.54.8-2.12.1-2.22.1-0.5-2.01.20.01.6-1.4-1.6-1.5-1.5-1.5-1.5-1.4-1.6-1.2-1.3
Locomotion distance, session 20.91.23.9-1.81.7-1.72.00.4-1.70.41.01.0-0.7-0.8-0.8-0.8-0.8-0.8-0.7-0.8-0.20.7
Locomotion velocity, session 31.51.74.0-1.62.0-2.01.9-0.1-1.70.91.41.2-1.2-1.2-1.1-1.1-1.2-1.2-1.1-1.1-0.8-0.6
Locomotion distance, session 30.60.74.80.00.20.00.21.1-0.1-0.72.2-0.60.60.50.70.70.50.60.60.71.01.3
Stereotopy head waving bouts, day 32.32.75.9-1.82.3-2.41.9-0.4-1.61.1-1.01.6-1.6-1.3-1.5-1.5-1.4-1.6-1.6-1.5-1.5-2.1
Stereotopy head waving duration, day 32.32.75.4-1.62.1-2.31.8-0.8-1.71.4-0.61.7-1.6-1.4-1.6-1.6-1.5-1.6-1.6-1.6-1.6-2.3
Locomotion velocity, session 73.33.67.20.8-0.91.1-0.72.71.2-2.51.8-2.02.22.02.22.22.12.22.22.22.41.0
Locomotion distance, session 74.35.58.01.4-1.92.2-1.52.71.8-2.71.6-2.52.62.42.62.62.52.62.72.62.81.8
Stereotopy head waving bouts, day 71.21.44.2-0.31.1-1.30.7-1.3-0.71.3-0.41.1-1.2-1.1-1.1-1.2-1.2-1.2-1.2-1.1-1.4-2.0
Stereotopy head waving duration, day 72.32.87.5-1.02.0-2.21.5-1.3-1.41.6-0.11.6-1.7-1.6-1.6-1.6-1.6-1.7-1.7-1.5-1.7-2.7
Locomotion velocity, session 80.60.71.9-0.40.8-0.90.6-0.8-0.60.8-0.20.8-0.9-1.0-0.8-0.8-1.0-0.9-0.9-0.6-1.0-1.4
Locomotion distance, session 80.10.10.8-0.40.3-0.30.50.5-0.2-0.30.20.0-0.0-0.20.10.1-0.10.0-0.00.20.10.9
Degree of sensitization distance0.50.51.10.6-1.01.1-0.80.30.9-0.7-0.8-0.60.70.70.70.70.70.70.70.70.5-0.3
Degree of sensitization stereotypy0.40.41.30.40.3-0.5-0.1-1.1-0.00.9-0.00.5-0.7-0.5-0.6-0.6-0.6-0.7-0.7-0.6-0.9-1.1
Conditioned locomotion1.31.52.2-1.41.3-1.41.5-0.7-1.31.10.01.2-1.3-1.4-1.2-1.3-1.4-1.3-1.3-1.3-1.1-0.4
Cocaine response after cond. corrected0.30.30.50.0-0.20.0-0.20.70.4-0.70.6-0.50.60.70.60.60.70.60.60.60.70.2
Cocaine response after cond. not corrected1.41.52.11.0-1.11.0-1.11.11.2-1.30.9-1.41.31.41.41.41.41.41.31.41.40.4
Cocaine response before conditioning1.21.42.71.6-1.51.6-1.20.81.2-1.00.8-1.31.11.01.21.21.11.21.11.31.20.2
Saline control response0.40.52.11.2-1.41.5-1.0-0.80.70.2-0.9-0.2-0.1-0.10.10.1-0.10.0-0.10.2-0.3-0.1
Bone: connectivity density1.72.66.82.6-2.62.4-2.6-0.42.1-0.60.4-1.61.41.31.31.31.31.41.31.20.91.3
Bone: cortical apparent density1.62.13.60.6-1.00.9-1.01.91.4-1.9-1.0-1.51.71.81.61.61.71.61.71.51.50.0
Bone: cortical area1.01.55.0-0.1-0.20.20.0-2.2-0.71.9-0.01.2-1.3-1.4-1.4-1.4-1.4-1.3-1.3-1.5-1.30.4
Bone: cortical porosity1.51.62.6-0.80.8-0.70.9-1.5-1.31.60.41.3-1.5-1.6-1.4-1.4-1.5-1.4-1.4-1.4-1.30.3
Bone: cortical porosity1.92.13.4-0.90.9-0.81.1-1.7-1.61.80.81.5-1.7-1.8-1.6-1.6-1.8-1.7-1.6-1.5-1.40.5
Bone: cortical thickness0.10.10.40.4-0.70.7-0.5-0.30.30.10.2-0.10.20.10.10.10.10.20.10.00.20.5
Bone: cortical thickness0.00.00.20.1-0.10.10.10.1-0.1-0.1-0.10.10.0-0.00.10.1-0.0-0.0-0.00.20.00.4
Bone: cortical tissue density1.52.03.60.5-0.90.8-1.01.91.3-1.9-1.2-1.41.71.81.61.61.71.61.61.51.5-0.0
Condit. Reinf. active minus inactive responses0.40.41.80.7-0.40.3-0.5-1.4-0.11.01.30.2-0.4-0.3-0.5-0.5-0.3-0.4-0.4-0.6-0.3-0.8
Condit. Reinf. active-inactive response ratio0.10.10.90.2-0.0-0.0-0.3-0.30.10.20.3-0.10.00.2-0.1-0.10.20.00.1-0.20.1-0.9
Condit. Reinf. active responses0.91.14.00.6-0.0-0.1-0.2-2.0-0.51.61.60.8-1.0-0.9-1.0-1.0-0.9-0.9-0.9-1.0-0.8-1.2
Condit. Reinf. inactive responses0.50.62.40.30.1-0.20.2-1.3-0.61.11.60.6-0.8-1.0-0.7-0.7-0.9-0.8-0.8-0.6-0.7-0.1
Incentive salience index mean1.01.24.40.40.00.00.1-2.0-0.81.82.10.9-1.1-1.0-1.2-1.1-1.0-1.0-1.0-1.2-0.8-0.3
Condit. Reinf. lever presses0.50.74.60.00.20.00.4-1.1-0.91.12.20.6-0.7-0.8-0.8-0.8-0.8-0.7-0.7-0.7-0.30.3
Condit. Reinf. active minus inactive responses0.10.10.4-0.10.4-0.40.20.0-0.20.10.60.1-0.2-0.1-0.1-0.1-0.1-0.1-0.20.0-0.0-0.6
Condit. Reinf. active-inactive response ratio0.40.41.7-0.61.0-1.10.7-0.2-0.60.40.30.5-0.6-0.5-0.5-0.5-0.5-0.5-0.6-0.4-0.5-1.3
Condit. Reinf. active responses0.00.10.4-0.10.3-0.30.30.0-0.40.20.70.1-0.3-0.2-0.2-0.2-0.3-0.2-0.3-0.1-0.0-0.0
Condit. Reinf. inactive responses0.40.51.80.8-0.91.0-0.60.50.6-0.50.2-0.70.50.60.60.60.60.60.60.60.61.3
Condit. Reinf. lever presses0.20.31.41.0-0.50.2-0.6-1.20.30.70.30.0-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.2-0.60.2
Condit. Reinf. lever reinforcers received0.30.40.90.20.2-0.20.2-0.9-0.50.90.70.5-0.8-0.8-0.7-0.7-0.8-0.7-0.8-0.6-0.6-0.2
Conditioned reinforcement - actives2.02.03.7-0.50.8-0.70.8-1.9-1.31.90.51.5-1.5-1.6-1.6-1.6-1.6-1.6-1.5-1.6-1.5-1.7
Conditioned reinforcement - inactives0.20.21.40.8-0.40.2-0.6-0.90.40.6-0.1-0.0-0.2-0.2-0.3-0.2-0.2-0.2-0.2-0.3-0.4-1.2
Conditioned locomotion0.40.51.1-0.40.4-0.20.6-0.8-0.90.90.90.7-0.7-1.1-0.7-0.7-0.9-0.7-0.8-0.6-0.7-0.3
Patch foraging indifference point 0 sec0.91.55.30.7-0.10.30.0-2.3-0.51.91.11.0-1.3-1.4-1.3-1.2-1.4-1.3-1.4-1.2-1.2-0.6
Patch foraging indifference point AUC3.03.56.3-0.41.2-1.41.2-2.3-1.82.52.11.7-2.0-2.0-2.0-2.0-2.0-2.0-2.1-1.9-1.7-2.2
Delay disc. indifference point, 0s delay0.80.94.1-0.20.6-0.90.1-1.2-0.30.8-2.00.9-0.8-0.6-0.9-0.9-0.7-0.9-0.8-0.9-1.3-0.9
Delay disc. indifference point, 16s delay2.32.33.4-1.31.0-0.81.2-1.7-1.61.7-0.51.8-1.8-1.8-1.7-1.7-1.8-1.7-1.8-1.6-1.7-0.5
Delay disc. indifference point, 2s delay0.30.31.00.20.3-0.30.1-1.0-0.30.90.30.5-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.6-0.7-0.1
Delay disc. indifference point, 24s delay3.13.05.5-0.80.9-0.91.0-2.4-1.32.2-0.41.9-2.2-2.1-1.9-2.0-2.0-2.0-2.0-1.9-2.1-1.1
Delay disc. indifference point, 4s delay0.70.71.4-1.00.9-0.61.0-0.5-1.20.7-0.10.9-1.0-1.0-0.8-0.8-1.0-0.8-1.1-0.8-0.80.2
Delay disc. indifference point, 8s delay0.30.30.9-0.0-0.10.40.2-1.0-0.50.80.70.5-0.6-0.9-0.5-0.5-0.8-0.5-0.7-0.5-0.50.1
Indifference point function ln k0.71.01.70.7-0.90.9-0.80.91.1-1.2-0.7-0.91.20.91.11.11.01.11.11.00.91.3
Indifference point function log k0.71.01.70.7-0.90.9-0.80.91.1-1.2-0.7-0.91.20.91.11.11.01.11.11.00.91.3
Patch foraging total patch changes 0 sec1.11.86.00.50.00.20.2-2.5-0.72.11.21.2-1.5-1.6-1.5-1.4-1.6-1.5-1.6-1.4-1.3-0.9
Patch foraging total patch changes 12 sec1.62.16.20.30.4-0.30.3-2.5-1.02.22.11.2-1.5-1.5-1.5-1.5-1.5-1.5-1.6-1.4-1.3-1.2
Patch foraging total patch changes 18 sec0.60.84.50.20.20.20.4-1.2-0.81.22.10.6-0.9-1.0-0.8-0.7-1.0-0.7-1.1-0.6-0.4-0.6
Patch foraging total patch changes 24 sec1.01.24.40.10.4-0.40.5-1.5-0.91.62.10.9-1.2-1.2-1.1-1.1-1.2-1.1-1.3-0.9-0.8-0.5
Patch foraging total patch changes 6 sec1.11.65.30.7-0.10.20.0-2.3-0.62.01.80.9-1.2-1.4-1.3-1.2-1.4-1.2-1.4-1.3-1.1-1.2
Patch foraging time to switch 0 sec9.614.828.01.4-2.12.3-2.25.33.2-5.10.0-4.14.44.54.44.44.44.44.44.34.32.9
Patch foraging water rate 0 sec3.35.38.9-1.01.5-1.51.5-3.0-2.02.90.42.5-2.6-2.7-2.6-2.6-2.6-2.6-2.6-2.5-2.4-2.2
Patch foraging water rate 12 sec0.30.41.51.2-1.21.2-1.0-0.90.70.3-0.5-0.20.0-0.10.00.1-0.10.10.10.1-0.2-0.3
Patch foraging water rate 18 sec0.60.82.4-0.4-0.10.0-0.0-1.6-0.41.1-1.30.9-0.8-1.0-1.0-1.0-0.9-1.0-0.8-1.0-1.20.3
Patch foraging water rate 24 sec0.30.51.80.1-0.20.30.0-1.3-0.41.00.30.6-0.7-0.9-0.7-0.7-0.9-0.7-0.7-0.7-0.6-0.6
Patch foraging water rate 6 sec2.63.89.5-0.30.9-0.70.8-3.1-1.42.70.32.1-2.3-2.4-2.3-2.2-2.3-2.2-2.2-2.1-2.2-0.9
Seeking ratio, delayed vs. immediate footshock0.70.82.3-1.51.1-1.01.50.3-1.30.41.50.8-0.5-0.8-0.6-0.6-0.8-0.6-0.7-0.60.00.1
Distance traveled before self-admin0.20.32.5-0.10.4-0.30.4-0.3-0.70.41.60.2-0.2-0.3-0.3-0.2-0.2-0.2-0.1-0.30.20.8
Distance traveled after self-admin0.10.10.6-0.50.5-0.70.10.5-0.1-0.5-0.8-0.00.30.30.20.20.30.20.40.10.1-0.3
Extensor digitorum longus weight1.87.117.44.0-4.23.9-4.1-0.13.7-1.5-1.0-2.62.32.32.32.32.32.32.22.41.40.7
Bone: elastic displacement2.02.22.81.6-1.21.1-1.51.31.7-1.50.7-1.71.61.61.71.61.61.61.61.61.5-1.3
Bone: elastic work3.14.05.92.4-2.02.0-2.01.42.2-1.72.0-2.22.22.02.22.22.02.12.12.22.20.5
Bone: endosteal estimation3.16.79.2-2.01.8-1.72.0-2.8-2.53.0-1.42.8-3.0-3.0-3.0-3.0-3.0-3.0-2.9-3.0-2.9-0.2
Bone: endosteal perimeter3.77.712.4-1.81.5-1.41.9-3.5-2.73.5-0.63.0-3.2-3.3-3.3-3.2-3.2-3.2-3.1-3.3-3.1-0.5
Epididymis fat weight0.30.71.30.2-0.70.8-0.51.10.6-1.1-0.3-0.91.00.71.00.90.81.00.90.71.1-0.5
Delta time in closed arm before/after self-admin0.20.21.20.40.2-0.4-0.1-0.7-0.00.61.10.2-0.4-0.2-0.3-0.3-0.2-0.3-0.3-0.3-0.3-0.5
Delta time in open arm before/after self-admin0.40.42.10.6-1.01.1-0.80.10.7-0.4-1.4-0.60.40.30.40.40.30.50.30.30.10.1
Diff in mean of infusions in LGA sessions0.60.62.1-1.51.2-1.31.10.0-0.90.3-0.80.8-0.6-0.5-0.6-0.7-0.5-0.6-0.4-0.7-0.50.3
Delay discount exponential model param2.02.13.21.0-0.90.7-1.11.81.5-1.8-0.1-1.61.81.81.61.61.81.61.81.61.60.3
Extinction: sum of active levers before priming3.23.27.72.8-2.22.2-2.30.22.0-1.01.8-1.81.61.71.71.61.61.61.61.71.51.5
Active lever presses in extinction session 62.22.16.62.6-1.71.3-2.2-0.31.9-0.41.6-1.51.31.51.31.21.51.21.61.21.1-0.2
Bone: final force0.20.35.5-0.1-0.30.40.1-0.1-0.10.1-0.30.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.12.3
Bone: final moment0.20.34.8-0.3-0.10.20.2-0.3-0.30.3-0.50.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.32.2
Food consumed during 24 hour testing period0.40.41.90.4-0.50.6-0.1-1.2-0.30.8-0.10.5-0.6-0.8-0.6-0.5-0.7-0.5-0.6-0.5-0.51.4
Glucose0.50.82.61.4-1.41.3-1.6-0.31.2-0.2-0.4-0.80.70.70.60.60.70.70.70.40.4-1.1
Heart weight0.20.33.00.8-0.50.4-0.9-0.90.50.50.2-0.2-0.1-0.2-0.1-0.1-0.2-0.0-0.1-0.1-0.3-1.7
Delay discount hyperbolic model param1.81.92.90.9-0.90.7-1.01.71.4-1.7-0.1-1.51.71.71.51.51.71.51.71.51.50.2
Intermittent access intake day 1-15 change0.90.92.71.4-1.61.7-1.5-0.01.1-0.6-0.5-0.90.80.60.80.80.70.80.70.80.40.3
Intermittent access intake escalation1.21.22.71.6-1.61.6-1.60.01.3-0.70.2-1.11.10.91.01.01.01.01.01.00.70.5
Intermittent access intake escalation 23.13.16.02.5-2.22.2-2.10.71.9-1.21.8-2.11.81.61.71.81.61.71.61.71.70.3
Intermitt. access day 1 inactive lever presses2.12.33.6-1.20.3-0.00.9-1.8-1.31.6-1.81.8-1.6-1.9-1.7-1.6-1.9-1.6-1.7-1.5-1.70.7
Intermitt. access day 15 inactive lever presses2.83.010.2-1.21.1-1.40.7-2.0-1.01.7-3.21.8-1.7-1.5-1.9-1.9-1.6-1.7-1.6-2.0-2.4-0.9
Intermitt. access escalation Index1.21.11.61.2-0.90.9-1.20.71.1-0.90.6-1.21.11.31.01.11.21.11.10.91.11.0
Intermittent access day 1 total infusions0.70.85.30.20.3-0.30.3-1.1-0.71.22.30.6-0.6-0.9-0.7-0.7-0.9-0.6-0.8-0.7-0.3-1.4
Intermittent access day 15 total infusions0.60.74.51.5-1.01.0-1.0-0.70.50.32.1-0.60.50.20.30.40.20.40.30.30.5-0.7
Intermittent access terminal intake (last 3 days)0.70.76.51.3-0.60.6-0.8-0.80.30.52.5-0.40.3-0.10.10.2-0.10.20.00.10.3-1.6
Intermittent access total infusions0.70.77.21.3-0.91.1-0.7-0.40.30.22.7-0.60.5-0.00.40.40.00.50.20.40.7-0.8
Intermittent access day 1 locomotion1.21.22.5-0.20.4-0.10.7-1.5-1.21.51.61.1-1.1-1.5-1.2-1.1-1.4-1.1-1.3-1.0-0.9-0.1
Intermittent access day 15 total locomotion0.40.41.81.0-1.11.3-0.8-0.20.7-0.10.6-0.40.50.20.40.40.30.40.40.50.40.7
Intermittent access total locomotion0.40.52.70.9-1.21.6-0.7-0.20.4-0.11.2-0.40.3-0.10.40.40.00.40.20.60.40.9
Intermittent access standard deviation0.20.20.80.9-0.70.7-0.7-0.80.20.40.7-0.1-0.0-0.10.00.0-0.10.00.00.1-0.2-0.5
Left kidney weight0.92.56.02.4-1.91.9-2.10.41.9-1.30.4-1.71.71.21.61.61.31.71.41.61.1-1.0
Right kidney weight1.13.15.12.1-2.12.2-2.30.82.1-1.7-0.0-2.01.81.41.91.91.51.91.61.81.4-1.6
Cocaine induced anxiety1.31.45.3-0.41.1-1.30.7-1.3-1.01.3-0.21.0-1.3-1.1-1.2-1.2-1.2-1.2-1.2-1.2-1.3-2.3
Post-drug Anxiety1.11.32.9-0.70.7-0.80.6-1.2-0.81.1-1.31.1-1.2-1.1-1.1-1.1-1.2-1.1-1.2-1.2-1.4-1.7
Baseline Anxiety0.40.51.8-0.3-0.20.2-0.01.30.4-1.0-0.6-0.60.80.80.70.70.70.70.70.60.80.5
Tail length0.61.75.22.3-2.02.3-1.7-0.71.3-0.21.8-1.00.60.40.80.90.50.80.71.10.71.7
Length with tail0.93.512.53.5-3.33.5-3.1-1.72.10.11.7-1.30.80.61.01.00.71.00.81.20.61.2
Length without tail0.51.03.61.9-1.91.9-1.7-1.21.00.31.1-0.60.50.20.40.40.30.50.30.50.30.6
Times rat made contact with spout0.60.71.50.2-0.80.8-0.31.20.6-1.1-0.7-0.70.80.80.90.90.70.90.70.90.91.2
Lifetime Intake0.40.54.61.1-0.70.9-0.7-0.30.30.12.1-0.50.50.00.40.40.10.40.20.30.6-0.6
Liver weight, left0.10.21.00.7-0.81.0-0.7-0.10.4-0.1-0.2-0.40.20.30.30.30.30.30.30.30.20.4
Liver weight, right0.30.51.10.9-0.91.1-0.90.20.6-0.50.6-0.70.60.60.70.70.60.70.60.80.7-0.2
Locomotor activity1.11.76.62.6-2.32.2-2.2-2.51.21.20.6-0.4-0.3-0.3-0.2-0.1-0.2-0.1-0.2-0.0-0.61.2
Locomotor testing distance1.52.59.73.1-2.92.7-2.7-1.62.00.31.0-1.20.60.60.70.70.60.70.70.80.31.3
Locomotor testing rearing3.85.915.33.9-3.53.6-3.4-0.12.8-0.92.5-2.51.91.92.02.01.92.01.92.21.72.2
Locomotion in novel chamber0.60.75.2-0.40.5-0.50.51.5-0.3-0.82.3-0.70.60.50.60.60.50.70.60.61.3-0.3
Locomotion in novel chamber post-restriction1.82.13.8-1.81.4-1.21.9-0.7-1.71.30.11.7-1.5-1.8-1.6-1.6-1.7-1.6-1.5-1.6-1.1-0.0
Fecal boli incidents, locomotor time 11.82.03.81.9-1.81.7-1.90.31.9-1.0-0.1-1.41.41.41.31.31.41.31.41.31.10.8
Change in fecal boli incidents, locomotor task0.10.10.20.3-0.20.3-0.30.20.3-0.3-0.3-0.20.40.40.30.30.40.20.40.30.10.1
Time >=10cm from walls, locomotor time 10.20.20.70.2-0.40.4-0.1-0.8-0.20.6-0.00.3-0.6-0.4-0.5-0.4-0.5-0.4-0.6-0.4-0.50.4
Bouts of movement, locomotor time 11.41.53.4-0.60.5-0.80.4-1.8-0.61.5-1.81.3-1.1-1.2-1.3-1.3-1.2-1.4-1.2-1.4-1.80.2
Total resting periods, locomotor time 11.61.83.9-0.60.6-0.80.5-1.9-0.71.6-1.91.5-1.3-1.4-1.4-1.5-1.4-1.5-1.4-1.5-2.0-0.0
Rest time, locomotor task time 13.33.76.6-1.41.1-1.21.1-2.3-1.42.2-2.32.1-2.1-2.1-2.1-2.1-2.1-2.2-2.1-2.2-2.6-0.3
Distance moved, locomotor task time 11.41.52.41.3-0.90.9-0.91.31.0-1.41.2-1.51.21.21.41.41.21.41.21.41.50.0
Vertical activity count, locomotor time 12.02.12.91.5-1.41.5-1.31.31.3-1.51.0-1.71.61.51.61.61.51.61.61.61.60.3
Time >=10cm from walls, locomotor time 20.50.53.11.6-1.01.0-1.0-0.70.40.31.8-0.50.10.00.20.30.00.40.00.30.20.1
Bouts of movement, locomotor time 20.40.50.6-0.80.7-0.70.7-0.6-0.80.7-0.00.8-0.7-0.7-0.7-0.8-0.7-0.7-0.7-0.8-0.70.1
Total resting periods, locomotor time 20.30.40.9-1.00.5-0.50.7-0.3-0.70.5-0.40.7-0.6-0.6-0.6-0.6-0.6-0.6-0.5-0.6-0.60.4
Rest time, locomotor task time 20.10.21.9-0.3-0.50.6-0.1-0.10.1-0.1-1.40.10.0-0.0-0.0-0.00.0-0.00.1-0.0-0.30.7
Distance moved, locomotor task time 20.20.21.60.60.4-0.60.0-0.5-0.20.61.30.0-0.3-0.3-0.3-0.3-0.3-0.2-0.4-0.3-0.1-0.4
Vertical activity count, locomotor time 20.10.10.7-0.00.7-0.80.3-0.0-0.20.20.70.1-0.1-0.0-0.2-0.2-0.1-0.1-0.1-0.2-0.1-0.2
Light reinforcement 11.12.04.21.9-1.82.0-1.60.61.4-1.01.5-1.51.21.21.31.41.31.31.31.51.31.3
Light reinforcement 21.72.24.3-1.71.6-1.21.8-1.0-2.11.40.81.8-1.6-1.7-1.5-1.5-1.6-1.6-1.6-1.4-1.20.6
Bone: marrow area3.16.89.5-2.01.7-1.72.0-2.9-2.53.1-1.42.8-3.0-3.0-3.0-3.0-3.0-3.0-2.9-3.1-2.9-0.2
Bone: maximum diameter4.68.514.9-1.81.7-1.71.7-3.9-2.63.8-0.53.1-3.3-3.4-3.4-3.4-3.4-3.3-3.3-3.6-3.2-0.7
Bone: maximum force0.40.72.6-0.50.1-0.10.5-1.0-0.71.0-0.30.8-0.9-1.0-0.9-0.9-1.0-0.9-0.9-0.8-0.81.6
Bone: maximum moment0.50.92.0-0.60.3-0.30.6-1.1-0.81.1-0.51.0-1.0-1.1-1.0-1.0-1.1-1.1-1.0-1.0-1.01.4
Mean time between licks in bursts0.40.55.3-0.10.4-0.8-0.3-0.20.5-0.1-2.30.1-0.10.3-0.1-0.10.2-0.20.2-0.2-0.8-1.5
Mean num. licks in bursts0.20.30.60.4-0.60.5-0.60.30.6-0.5-0.4-0.50.50.60.50.50.60.50.50.50.40.8
Cd content in liver1.11.22.01.4-1.31.4-1.40.51.2-0.90.5-1.11.11.21.11.11.21.11.21.01.10.6
Co content in liver0.60.71.31.1-0.90.8-1.10.21.0-0.61.0-1.00.90.80.80.80.80.90.80.80.80.1
Cu content in liver0.30.41.10.3-0.30.2-0.00.80.2-0.71.0-0.60.60.60.60.60.60.60.60.70.80.5
Fe content in liver0.30.30.60.1-0.30.2-0.30.80.5-0.8-0.5-0.60.60.60.60.60.60.60.60.60.50.4
K content in liver3.93.810.0-3.02.8-2.63.20.1-2.81.10.91.9-1.7-1.8-1.6-1.6-1.8-1.7-1.8-1.5-1.00.8
Mg content in liver1.71.86.3-2.52.1-1.92.51.0-2.00.10.21.1-0.9-1.0-0.8-0.8-1.0-0.9-0.9-0.7-0.30.7
Mn content in liver7.07.910.7-2.93.2-3.23.3-1.8-3.12.6-0.33.1-3.0-3.1-2.9-2.9-3.1-3.0-3.1-2.8-2.6-1.3
Na content in liver0.40.53.0-0.70.2-0.00.71.2-0.4-0.70.8-0.20.30.30.40.40.30.30.30.60.71.7
Rb content in liver1.01.33.8-1.91.8-1.82.00.6-1.40.2-0.31.0-0.9-0.8-0.8-0.8-0.9-0.9-0.9-0.8-0.50.7
Se content in liver0.70.93.2-1.31.3-1.11.51.8-1.0-0.91.3-0.00.30.30.30.30.30.30.30.30.91.0
Sr content in liver0.80.81.11.0-0.91.0-1.00.51.1-0.70.3-1.00.90.90.90.90.90.90.90.90.81.0
Zn content in liver0.60.66.7-0.30.4-0.20.70.2-0.70.22.60.2-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.10.61.8
Bone: minimum diameter1.12.04.7-0.60.3-0.40.6-2.2-1.22.10.01.4-1.6-1.7-1.7-1.7-1.7-1.6-1.6-1.8-1.5-0.2
Time in familiar zone, hab. session 11.41.31.71.2-1.31.3-1.10.91.1-1.10.8-1.21.21.21.21.21.21.21.21.31.10.8
Time in novel zone, hab. session 11.01.02.9-0.80.6-0.70.5-1.0-0.50.9-1.70.9-1.0-0.9-1.1-1.0-1.0-1.0-1.0-1.2-1.2-1.2
Total zone transitions, hab. session 11.92.66.3-1.82.4-2.52.3-0.4-2.01.21.41.6-1.4-1.6-1.4-1.4-1.6-1.5-1.4-1.3-1.0-0.7
Total locomotion distance, hab. session 10.40.62.6-1.31.4-1.41.60.9-1.1-0.20.80.5-0.3-0.4-0.2-0.3-0.4-0.3-0.3-0.10.10.2
Locomotion velocity, hab. session 11.21.75.1-1.82.2-2.02.30.3-1.90.61.51.2-1.0-1.1-0.9-0.9-1.1-1.0-1.0-0.8-0.40.1
Time in familiar zone, hab. session 22.42.43.41.0-1.61.5-1.31.61.6-1.9-0.6-1.61.71.71.71.71.71.71.71.71.51.3
Time in novel zone, hab. session 22.22.23.8-0.61.1-1.20.9-1.9-1.32.00.11.5-1.6-1.6-1.7-1.7-1.6-1.7-1.6-1.8-1.6-1.3
Total zone transitions, hab. session 24.05.29.7-2.83.0-2.93.1-0.8-2.81.80.52.4-2.3-2.5-2.3-2.2-2.4-2.3-2.3-2.2-1.7-0.4
Total locomotion distance, hab. session 22.63.46.9-2.42.6-2.32.6-0.4-2.41.30.31.9-1.9-2.0-1.8-1.8-2.0-1.8-1.8-1.7-1.3-0.3
Locomotion velocity, hab. session 23.34.58.8-2.72.9-2.73.0-0.6-2.71.60.52.2-2.1-2.3-2.1-2.0-2.3-2.0-2.1-2.0-1.4-0.4
Novel to familiar place preference ratio0.70.71.4-0.40.6-0.70.6-1.1-0.91.20.20.9-0.8-0.9-1.0-1.0-0.9-1.0-0.9-1.1-0.9-0.3
Novelty place preference1.31.32.8-0.40.6-0.70.6-1.6-1.01.70.21.2-1.1-1.2-1.3-1.3-1.2-1.3-1.2-1.4-1.2-0.7
Time in novel zone, NPP test0.80.82.1-0.20.3-0.50.3-1.4-0.71.4-0.01.0-0.9-1.0-1.1-1.1-1.0-1.1-1.0-1.2-1.1-0.8
Total zone transitions, NPP test1.21.73.6-1.51.8-1.71.9-0.4-1.71.01.31.3-1.2-1.3-1.2-1.2-1.3-1.2-1.3-1.2-0.7-0.2
Total locomotion distance, NPP test1.41.94.4-1.71.8-1.62.1-0.3-1.91.10.91.4-1.4-1.5-1.3-1.3-1.5-1.3-1.4-1.3-0.80.1
Locomotion velocity, NPP test1.01.43.5-1.41.5-1.31.9-0.2-1.70.91.21.2-1.1-1.3-1.1-1.0-1.3-1.1-1.1-1.0-0.60.2
Intraocular pressure1.01.43.01.7-1.61.3-1.70.11.4-0.8-0.0-1.31.21.11.11.11.01.21.01.20.6-1.3
Delta distance traveled before/after self-admin0.40.43.3-1.00.9-1.20.30.5-0.2-0.3-1.80.20.10.30.0-0.10.2-0.10.1-0.1-0.3-1.1
Delta ambulatory time before/after self-admin0.50.65.6-1.20.9-1.20.40.6-0.2-0.4-2.40.3-0.00.3-0.0-0.10.2-0.10.1-0.1-0.4-0.9
Parametrial fat weight2.44.67.72.8-2.32.5-2.31.32.5-1.91.3-2.42.22.12.22.32.12.22.22.42.20.1
Pavlov. Cond. lever latency0.91.23.30.7-0.90.6-1.11.01.4-1.2-1.8-1.11.11.31.11.11.21.11.11.00.6-0.4
Pavlov. Cond. magazine entry latency0.50.72.1-1.41.1-0.81.40.8-1.30.01.50.4-0.3-0.2-0.3-0.3-0.2-0.2-0.3-0.40.41.2
Pavlov. Cond. change in total contacts0.80.81.3-1.01.0-1.01.1-0.7-1.10.90.11.0-0.9-0.9-1.0-1.0-0.9-0.9-0.9-1.1-0.7-0.1
Pavlov. Cond. index score0.81.02.7-1.41.3-1.01.5-0.1-1.60.71.60.9-0.8-0.9-0.9-0.8-0.9-0.8-0.8-0.9-0.10.9
Pavlov. Cond. latency score0.91.12.7-1.31.3-1.01.6-0.2-1.60.81.61.0-0.9-1.0-1.0-0.9-1.0-0.9-0.9-1.0-0.30.8
Pavlov. Cond. lever contacts0.30.43.6-0.10.20.00.4-0.3-0.60.51.90.3-0.3-0.4-0.3-0.3-0.3-0.3-0.2-0.20.21.2
Pavlov. Cond. magazine entry number0.91.13.21.8-1.51.3-1.8-0.41.6-0.5-1.1-0.90.70.70.80.80.70.70.70.90.1-0.7
Pavlov. Cond. intertrial magazine entries1.21.53.01.6-1.31.2-1.70.51.7-1.1-0.6-1.31.21.31.21.21.31.21.31.30.8-0.1
Pavlov. Cond. lever-magazine prob. diff.0.70.82.2-1.31.2-0.91.50.1-1.40.61.50.8-0.7-0.8-0.7-0.7-0.7-0.7-0.7-0.7-0.00.8
Pavlov. Cond. response bias0.70.92.2-1.31.1-0.91.40.0-1.40.61.50.8-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.7-0.11.1
Pavlov. Cond. lever latency0.60.83.5-0.60.40.00.41.9-0.1-1.30.8-0.60.90.90.90.90.90.90.90.91.40.1
Pavlov. Cond. magazine entry latency0.00.00.1-0.20.2-0.10.20.1-0.1-0.10.00.1-0.00.0-0.0-0.00.00.0-0.0-0.00.0-0.3
Pavlov. Cond. change in total contacts0.50.73.21.2-0.60.2-0.8-1.80.41.10.10.3-0.6-0.6-0.5-0.6-0.5-0.6-0.6-0.4-1.0-1.3
Pavlov. Cond. index score0.30.31.80.7-0.50.2-0.5-1.40.20.90.00.3-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.8-0.3
Pavlov. Cond. latency score0.30.42.00.5-0.30.1-0.3-1.4-0.11.00.30.4-0.6-0.7-0.6-0.6-0.6-0.6-0.7-0.6-0.8-0.3
Pavlov. Cond. lever contacts0.30.41.80.7-0.60.2-0.6-1.30.30.8-0.80.2-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.90.2
Pavlov. Cond. magazine entry number0.40.51.30.1-0.30.3-0.11.10.4-0.90.4-0.70.80.70.80.80.70.70.70.80.90.9
Pavlov. Cond. intertrial magazine entries0.20.21.1-0.50.3-0.40.50.1-0.30.1-0.50.3-0.4-0.6-0.3-0.3-0.6-0.3-0.6-0.3-0.41.1
Pavlov. Cond. lever-magazine prob. diff.0.30.31.80.7-0.50.3-0.5-1.40.20.9-0.30.3-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.5-0.8-0.4
Pavlov. Cond. response bias0.20.31.20.7-0.40.1-0.5-1.10.30.7-0.70.2-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.8-0.5
Time in closed arm before self-admin0.40.41.6-1.00.8-0.51.01.3-0.6-0.61.2-0.10.40.20.30.30.30.30.50.30.90.1
Time in closed arm after self-admin0.60.63.0-1.11.4-1.51.20.4-0.90.21.70.5-0.2-0.2-0.3-0.3-0.2-0.4-0.1-0.30.2-0.1
Time in open arm before self-admin1.01.13.6-0.31.5-1.90.8-1.0-0.91.11.01.0-1.0-0.8-1.0-1.0-0.9-1.0-1.0-0.9-0.9-0.9
Time in open arm after self-admin0.60.71.5-0.40.5-0.40.8-0.7-1.00.9-0.00.7-1.0-1.2-1.0-0.9-1.2-0.8-1.1-0.9-0.9-0.3
Bone: periosteal estimation3.57.311.6-1.81.5-1.41.8-3.4-2.43.4-1.12.9-3.1-3.2-3.2-3.2-3.1-3.1-3.0-3.3-3.0-0.2
Bone: periosteal perimeter2.44.07.4-1.11.0-0.91.1-2.7-1.82.7-0.12.1-2.3-2.3-2.4-2.4-2.3-2.3-2.3-2.4-2.2-0.4
Bone: post-yield work1.31.83.0-0.90.6-0.50.9-1.6-1.11.6-1.11.4-1.6-1.7-1.5-1.5-1.7-1.6-1.6-1.3-1.70.2
Progressive ratio test 1 active lever presses0.30.31.10.30.1-0.1-0.1-1.0-0.30.90.80.4-0.5-0.6-0.5-0.5-0.6-0.5-0.7-0.5-0.5-0.7
Progressive ratio test 1 breakpoint0.70.71.5-0.10.5-0.50.4-1.2-0.71.20.80.8-0.9-1.0-0.9-0.9-1.0-0.9-1.0-0.8-0.9-1.0
Progressive ratio test 1 inactive lever presses1.11.23.2-0.10.2-0.00.3-1.8-0.81.50.41.1-1.1-1.5-1.2-1.2-1.5-1.1-1.5-1.1-1.2-1.2
Progressive ratio test 2 active lever presses0.30.34.1-0.20.5-0.40.50.1-0.60.32.00.1-0.0-0.3-0.2-0.2-0.2-0.1-0.2-0.20.3-0.7
Progressive ratio test 2 breakpoint0.40.45.6-0.10.4-0.10.50.2-0.70.22.4-0.0-0.0-0.4-0.1-0.1-0.3-0.1-0.2-0.10.4-0.7
Progressive ratio test 2 inactive lever presses0.50.61.60.40.10.00.1-1.3-0.51.21.20.6-0.7-1.0-0.8-0.8-0.9-0.7-0.7-0.7-0.7-0.9
Incentive Sensitization - Responses1.01.06.3-0.50.5-0.20.71.7-0.4-1.02.5-0.70.90.40.70.80.50.80.60.81.60.4
Incentive Sensitization - Breakpoint1.01.06.7-0.40.4-0.10.61.7-0.4-1.02.6-0.80.90.40.70.80.50.80.60.81.60.5
Sum of active levers in priming session hrs 5-60.70.62.61.6-1.00.7-1.2-0.31.0-0.10.9-0.80.70.70.60.60.70.60.80.50.40.7
Progressive ratio1.61.88.4-1.81.7-1.81.4-0.2-0.90.5-2.91.3-1.1-0.8-1.2-1.2-0.9-1.2-0.9-1.2-1.5-1.1
Food seeking constrained by brief footshock0.81.02.2-0.71.3-1.50.8-0.6-0.80.7-1.41.0-0.9-0.7-0.9-0.9-0.9-0.9-1.0-1.0-1.1-1.3
Seeking ratio, punishment vs. effort0.30.42.21.2-0.70.6-0.8-0.20.4-0.11.5-0.60.40.40.50.50.30.50.20.50.6-0.1
Retroperitoneal fat weight2.89.111.42.4-2.83.1-2.72.82.9-3.30.4-3.23.43.13.33.33.23.43.43.23.32.5
Reaction time number correct0.71.11.51.1-1.01.0-1.00.91.0-0.91.2-1.21.10.91.11.10.91.11.01.11.10.8
Reaction time mean minus median2.53.411.8-3.03.4-3.23.00.8-2.60.51.11.4-1.3-1.2-1.3-1.3-1.2-1.2-1.2-1.2-0.5-0.3
Reaction time mean minus median AUC1.82.37.6-2.42.8-2.52.50.6-2.10.50.91.2-1.2-1.1-1.1-1.1-1.1-1.1-1.1-1.0-0.6-0.7
Reaction time num false alarms0.40.61.5-0.50.2-0.40.3-0.9-0.50.8-1.20.7-0.8-0.7-0.8-0.8-0.7-0.8-0.8-0.8-1.00.4
Reaction time num false alarms AUC0.50.72.3-0.60.5-0.70.4-0.9-0.50.8-1.50.8-0.9-0.8-0.8-0.9-0.8-0.9-0.9-0.8-1.10.1
Reaction time trials correct on left0.71.11.51.1-1.01.0-1.00.91.0-0.91.2-1.21.10.91.11.10.91.11.01.11.10.8
Reaction time trials on left0.60.81.21.0-0.80.8-0.90.80.8-0.81.1-1.11.00.81.01.00.81.00.91.01.00.8
Reaction time mean0.40.62.8-0.71.5-1.70.61.2-0.2-0.70.5-0.30.40.60.30.30.60.30.50.20.5-1.0
Reaction time mean AUC0.50.72.1-0.51.3-1.40.41.4-0.1-0.90.7-0.50.60.80.60.50.80.60.70.50.7-1.0
Median of all reaction times0.70.91.80.40.6-0.9-0.51.30.8-1.20.2-1.01.01.31.01.01.31.01.20.90.9-1.0
Reaction time omissions3.14.212.1-2.73.4-3.52.7-0.2-2.51.2-0.61.9-1.8-1.5-1.8-1.8-1.6-1.7-1.7-1.9-1.5-1.9
Reaction time false alarm rate0.91.33.9-0.90.7-0.90.6-1.3-0.71.1-2.01.2-1.3-1.0-1.2-1.3-1.1-1.2-1.2-1.2-1.5-0.4
Reaction time premature initiation rate0.40.61.80.3-0.10.00.1-1.3-0.41.11.30.6-0.8-0.9-0.7-0.7-0.8-0.7-0.9-0.6-0.7-0.8
Reaction time premature initiations0.30.44.30.9-0.50.5-0.3-0.80.00.62.1-0.0-0.3-0.5-0.1-0.2-0.4-0.2-0.40.0-0.1-0.3
Std. dev. reaction times1.62.39.3-2.53.0-3.02.40.8-1.90.30.11.1-1.0-0.8-1.0-1.0-0.8-0.9-0.9-1.1-0.5-0.8
Reaction time trials completed0.60.81.21.0-0.80.8-0.90.80.8-0.81.1-1.11.00.81.01.00.81.00.91.01.00.8
Reaction time trials AUC0.81.11.51.2-1.11.1-1.10.81.0-0.91.0-1.21.10.91.11.11.01.21.11.11.10.9
Run reversals in cocaine runway, females2.62.68.8-2.31.8-1.71.6-0.5-1.30.8-3.01.7-1.5-1.3-1.4-1.4-1.5-1.5-1.6-1.4-1.5-0.8
Run reversals in cocaine runway, males0.50.56.80.60.2-0.1-0.00.2-0.10.02.6-0.40.30.30.30.30.40.30.40.30.71.0
Latency to leave start box in cocaine runway0.10.11.0-0.30.1-0.30.10.60.2-0.5-1.0-0.00.20.30.20.10.20.20.10.10.1-0.4
Latency to leave start box in cocaine runway, F0.30.33.2-0.60.6-0.70.30.60.1-0.5-1.80.2-0.10.20.10.00.20.00.0-0.0-0.1-0.6
Latency to leave start box in cocaine runway, M0.10.10.40.0-0.60.60.0-0.1-0.10.10.3-0.0-0.0-0.3-0.1-0.1-0.2-0.0-0.2-0.10.00.0
Std. dev. time between licks in bursts0.20.20.50.10.4-0.60.00.60.2-0.50.7-0.40.50.60.50.40.60.40.60.40.5-0.1
Total sessions with >9 infusions0.40.41.70.7-1.11.3-0.7-1.10.30.5-0.70.1-0.1-0.5-0.2-0.2-0.4-0.2-0.3-0.2-0.60.8
Short access day 1 total inactive lever presses1.51.66.52.6-2.12.1-2.2-1.01.70.01.0-1.10.80.40.70.80.40.90.40.80.4-0.9
Short access day 10 total inactive lever presses1.71.83.0-0.81.0-1.11.1-1.6-1.31.7-0.31.5-1.5-1.4-1.6-1.6-1.5-1.6-1.5-1.5-1.5-0.3
Short access day 1 total infusions0.70.73.01.7-1.31.4-1.4-0.80.80.21.3-0.70.60.30.40.50.30.50.40.40.20.2
Short access day 10 total infusions0.30.31.4-0.00.10.10.2-0.8-0.60.71.20.5-0.4-0.7-0.5-0.5-0.6-0.4-0.5-0.5-0.3-0.7
Short access total infusions0.50.55.40.9-0.60.8-0.6-0.20.20.02.3-0.60.50.10.40.40.10.50.30.40.6-0.4
Short access day 1 locomotion0.30.41.61.1-1.01.1-0.8-0.50.40.11.3-0.40.30.00.30.30.20.30.10.30.20.2
Short access day 10 total locomotion0.20.21.50.4-0.60.8-0.4-0.40.00.20.30.1-0.0-0.1-0.00.0-0.0-0.0-0.00.2-0.01.2
Short access total locomotion0.20.20.90.6-0.60.9-0.5-0.8-0.00.41.00.1-0.1-0.3-0.1-0.1-0.2-0.1-0.10.0-0.20.7
One hour access (0.3 mA shock)0.60.73.21.7-1.11.2-1.2-1.10.60.51.8-0.40.30.00.20.20.10.20.20.30.2-0.4
Compulsive drug intake1.01.03.3-1.11.2-1.60.8-0.6-0.60.7-1.81.0-1.0-0.4-1.0-1.0-0.6-0.9-0.7-1.1-1.10.6
One hour access (shock baseline)1.31.58.12.0-1.31.5-1.4-0.00.8-0.32.9-1.11.10.60.91.00.70.90.81.01.1-1.0
Social response proportion0.20.20.50.10.3-0.6-0.0-0.70.10.5-0.60.4-0.5-0.3-0.4-0.5-0.4-0.5-0.4-0.4-0.7-0.6
Social responses0.20.30.80.20.3-0.5-0.1-0.9-0.10.8-0.40.5-0.6-0.3-0.6-0.6-0.3-0.6-0.4-0.6-0.7-0.4
Social time0.60.83.31.8-1.51.2-1.7-0.81.40.1-0.1-0.80.40.50.50.50.40.40.40.5-0.1-0.4
Soleus weight0.51.34.50.4-0.50.3-0.0-2.1-0.51.7-0.31.1-1.3-1.3-1.2-1.2-1.3-1.3-1.3-1.1-1.51.1
Bone: stiffness1.42.33.2-1.81.2-1.11.7-1.0-1.81.5-0.41.6-1.6-1.7-1.6-1.6-1.7-1.6-1.6-1.6-1.31.5
Tibialis anterior weight1.75.715.94.0-3.73.4-3.9-0.43.4-1.1-0.6-2.32.02.02.02.02.02.01.92.11.10.8
Time to tail flick, vehicle, before self-admin0.30.30.5-0.50.3-0.30.7-0.4-0.70.6-0.40.6-0.6-0.7-0.7-0.6-0.7-0.6-0.7-0.6-0.60.1
Time to tail flick, vehicle, after self-admin1.21.21.8-1.30.8-0.61.0-0.9-1.11.1-0.61.3-1.3-1.4-1.3-1.2-1.3-1.2-1.3-1.2-1.0-0.5
Time to tail flick, test, before self-admin0.50.41.91.0-0.30.4-0.50.30.6-0.41.4-0.70.50.60.60.60.60.50.50.70.7-0.9
Time to tail flick, test, after self-admin0.70.74.71.1-1.21.0-1.3-0.51.2-0.1-2.2-0.50.30.60.30.30.60.20.60.3-0.5-0.4
Delta time to tail flick, vehicle, before/after SA0.50.50.8-0.70.4-0.30.5-0.7-0.60.7-0.80.8-0.9-0.9-0.8-0.8-0.9-0.8-0.8-0.8-0.8-0.7
Delta time to tail flick, test, before/after SA0.70.79.3-0.6-0.60.5-0.1-0.10.1-0.0-3.00.2-0.2-0.1-0.3-0.3-0.1-0.2-0.1-0.4-0.81.2
Tibia length0.61.76.1-0.2-0.50.80.0-2.0-0.71.5-1.61.3-1.2-1.4-1.3-1.3-1.3-1.2-1.2-1.3-1.32.5
Ambulatory time before self-admin0.20.22.80.10.3-0.30.2-0.2-0.40.31.70.1-0.1-0.1-0.1-0.1-0.1-0.1-0.0-0.10.30.5
Ambulatory time after self-admin0.40.40.8-0.10.4-0.6-0.20.90.3-0.9-0.5-0.50.70.90.70.60.90.60.80.60.5-0.9
Bone: tissue strength0.20.20.70.0-0.20.1-0.20.90.5-0.7-0.1-0.60.60.50.60.50.50.60.60.50.6-0.2
Total heroin consumption0.30.31.31.1-0.50.3-1.0-0.90.80.2-1.0-0.20.10.30.10.00.30.10.3-0.0-0.30.1
Bone: trabecular number2.13.37.92.5-2.72.8-2.50.12.1-1.10.0-1.81.61.51.61.61.51.61.61.71.22.2
Bone: trabecular spacing0.50.73.9-1.31.0-0.81.32.0-0.6-1.10.3-0.10.40.40.50.50.40.40.50.60.9-0.1
Bone: trabecular thickness0.40.51.81.3-1.00.9-1.3-0.61.1-0.1-0.4-0.60.40.40.40.40.40.40.40.5-0.10.1
Bone: trabecular tissue density1.62.34.7-2.12.1-2.22.1-0.4-1.91.10.21.6-1.5-1.4-1.5-1.5-1.4-1.5-1.4-1.4-1.1-0.6
Water consumed over 24 hours0.91.13.31.2-1.71.8-1.20.21.1-0.7-0.2-0.90.80.70.90.90.70.90.70.90.81.8
Number of responses in last shaping day0.20.30.5-0.30.3-0.20.2-0.7-0.70.70.40.5-0.5-0.7-0.5-0.5-0.6-0.5-0.6-0.5-0.5-0.1