Hub : Genes

LOC120103482

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression LOC120103482 0.12 0.06 3.6e-04 0.07 0.06 0.06 0.08 1.9e-04 2.2e-04 2.8e-04 4.6e-05
2 NAcc gene expression LOC120103482 0.11 0.05 1.1e-08 0.07 0.09 0.07 0.09 6.8e-09 3.1e-10 6.6e-09 3.8e-10
3 Adipose gene expression LOC120103482 0.2 0.07 3.1e-12 0.08 0.09 0.09 0.08 3.6e-09 6.3e-10 6.4e-10 1.7e-09
4 LHb gene expression LOC120103482 0.2 0.11 6.3e-03 0.05 0.09 0.03 0.08 2.4e-02 3.3e-03 5.9e-02 6.8e-03
5 PL gene expression LOC120103482 0.11 0.06 3.9e-07 0.05 0.04 0.04 0.06 3.0e-06 1.4e-05 2.9e-05 1.3e-07
6 IL gene expression LOC120103482 0.18 0.1 8.6e-03 0.02 0.05 0.02 0.04 9.5e-02 2.4e-02 1.3e-01 3.3e-02
7 Brain gene expression LOC120103482 0.16 0.08 2.4e-07 0.04 0.07 0.07 0.06 1.7e-04 8.1e-07 8.1e-07 2.0e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density4.57.610.3-2.4-2.82.7-2.6-2.7-2.73.2
Area under the delay curve1.31.32.3-1.4-1.31.4-0.2-1.0-0.71.5
BMI with tail0.30.92.70.40.5-0.6-1.01.3-0.1-1.7
BMI without tail0.40.83.70.30.5-0.5-0.31.10.4-1.9
Body weight1.87.312.62.12.6-2.61.63.52.4-3.5
Weight adjusted by age1.21.32.0-0.8-1.31.3-1.0-1.4-1.21.1
Bone surface1.93.46.0-1.5-1.81.8-1.5-1.8-1.72.4
Bone volume1.93.26.1-1.5-1.71.8-1.4-1.7-1.72.5
Breakpoint value in progressive ratio session0.50.51.2-1.1-0.80.4-0.9-0.8-0.50.1
Number of licking bursts0.20.20.50.10.2-0.40.10.70.4-0.6
Context. condit. distance diff. score0.70.91.11.01.0-1.00.91.11.0-0.7
Locomotion velocity, session 11.31.43.1-0.7-1.01.2-1.8-1.1-1.50.4
Locomotion distance, session 11.52.03.2-1.2-1.51.4-1.8-1.5-1.60.5
Locomotion velocity, session 20.40.40.6-0.7-0.70.8-0.6-0.8-0.70.5
Locomotion distance, session 20.60.82.5-0.6-0.70.6-1.6-0.7-1.2-0.1
Locomotion velocity, session 33.54.15.5-1.9-2.22.2-1.7-2.4-1.91.8
Locomotion distance, session 31.21.32.8-1.7-1.31.3-1.0-0.9-0.70.4
Stereotopy head waving bouts, day 31.01.12.3-1.5-1.21.50.0-0.9-0.41.1
Stereotopy head waving duration, day 30.40.50.9-0.9-0.80.90.1-0.8-0.30.8
Locomotion velocity, session 72.72.96.2-1.7-2.01.6-2.5-1.3-1.80.5
Locomotion distance, session 70.20.21.0-0.2-0.30.1-1.00.4-0.6-0.2
Stereotopy head waving bouts, day 70.20.20.7-0.1-0.30.20.0-0.7-0.30.8
Stereotopy head waving duration, day 71.01.32.0-0.9-1.11.3-0.5-1.4-1.01.3
Locomotion velocity, session 81.72.04.7-1.2-1.41.5-2.2-1.0-1.60.2
Locomotion distance, session 80.10.10.30.10.0-0.3-0.50.2-0.1-0.5
Degree of sensitization distance1.11.12.51.61.2-1.30.31.30.4-0.6
Degree of sensitization stereotypy0.00.00.10.20.1-0.20.1-0.3-0.10.2
Conditioned locomotion1.92.22.6-1.5-1.61.4-1.4-1.5-1.41.6
Cocaine response after cond. corrected2.12.33.4-1.1-1.51.5-1.6-1.8-1.71.3
Cocaine response after cond. not corrected2.52.83.9-1.3-1.81.8-1.6-2.0-1.71.4
Cocaine response before conditioning0.30.41.1-1.0-0.60.70.5-0.40.40.3
Saline control response0.71.03.5-1.9-0.80.70.7-1.10.80.3
Bone: connectivity density6.09.410.4-2.8-3.13.0-2.9-3.1-3.13.2
Bone: cortical apparent density0.40.50.8-0.9-0.70.7-0.6-0.9-0.40.3
Bone: cortical area0.10.10.3-0.3-0.20.1-0.1-0.3-0.00.6
Bone: cortical porosity1.61.84.90.1-0.91.1-0.9-1.3-1.82.2
Bone: cortical porosity1.41.54.10.2-0.80.9-0.9-1.2-1.72.0
Bone: cortical thickness0.10.20.50.60.5-0.70.2-0.00.20.2
Bone: cortical thickness0.70.81.6-0.4-0.80.7-1.2-0.7-1.30.9
Bone: cortical tissue density0.30.40.7-0.8-0.70.7-0.6-0.9-0.40.2
Condit. Reinf. active minus inactive responses0.91.02.61.30.8-0.8-0.61.00.1-1.6
Condit. Reinf. active-inactive response ratio0.20.31.00.3-0.10.1-1.0-0.3-0.5-0.6
Condit. Reinf. active responses0.40.51.60.80.2-0.3-0.90.7-0.4-1.3
Condit. Reinf. inactive responses0.10.10.40.3-0.10.1-0.60.3-0.5-0.3
Incentive salience index mean0.30.30.90.6-0.10.1-0.90.2-0.5-0.8
Condit. Reinf. lever presses0.50.60.9-0.3-0.90.8-0.9-0.9-1.00.4
Condit. Reinf. active minus inactive responses0.10.10.3-0.30.0-0.10.20.50.3-0.4
Condit. Reinf. active-inactive response ratio0.00.00.1-0.1-0.10.10.20.30.20.1
Condit. Reinf. active responses0.10.10.3-0.20.2-0.30.50.40.5-0.4
Condit. Reinf. inactive responses0.00.00.2-0.4-0.10.10.1-0.20.1-0.1
Condit. Reinf. lever presses0.10.10.6-0.1-0.1-0.1-0.40.20.1-0.8
Condit. Reinf. lever reinforcers received0.10.10.3-0.20.1-0.20.10.30.3-0.6
Conditioned reinforcement - actives0.40.40.9-0.6-0.70.2-0.5-0.9-0.00.9
Conditioned reinforcement - inactives0.70.82.0-1.2-0.90.7-0.7-1.4-0.1-0.3
Conditioned locomotion0.50.62.4-1.5-0.60.40.3-0.70.70.0
Patch foraging indifference point 0 sec0.10.10.3-0.3-0.30.60.0-0.2-0.30.4
Patch foraging indifference point AUC0.30.40.8-0.7-0.80.9-0.6-0.2-0.40.4
Delay disc. indifference point, 0s delay0.40.51.01.00.7-0.70.80.40.4-0.3
Delay disc. indifference point, 16s delay1.91.93.3-1.2-1.51.7-0.8-1.3-1.31.8
Delay disc. indifference point, 2s delay1.21.33.3-1.0-1.11.1-0.3-1.2-0.91.8
Delay disc. indifference point, 24s delay3.73.65.3-2.1-2.22.3-1.1-1.6-1.52.2
Delay disc. indifference point, 4s delay1.11.22.5-0.6-1.11.6-0.5-0.8-1.21.4
Delay disc. indifference point, 8s delay1.21.22.8-1.7-1.31.3-0.4-0.9-0.61.0
Indifference point function ln k0.20.20.60.4-0.00.0-0.2-0.6-0.60.8
Indifference point function log k0.20.20.60.4-0.00.0-0.2-0.6-0.60.8
Patch foraging total patch changes 0 sec0.00.00.1-0.1-0.10.4-0.00.1-0.2-0.1
Patch foraging total patch changes 12 sec0.00.00.10.1-0.00.1-0.20.3-0.1-0.3
Patch foraging total patch changes 18 sec0.10.20.6-0.8-0.30.60.30.00.4-0.2
Patch foraging total patch changes 24 sec0.70.92.10.40.8-0.51.51.11.2-0.4
Patch foraging total patch changes 6 sec0.00.10.1-0.2-0.30.3-0.20.1-0.20.2
Patch foraging time to switch 0 sec0.50.82.0-1.4-1.00.9-0.8-0.7-0.60.4
Patch foraging water rate 0 sec0.10.10.40.60.1-0.10.1-0.3-0.20.6
Patch foraging water rate 12 sec1.01.64.02.01.5-1.21.20.80.6-1.0
Patch foraging water rate 18 sec0.81.02.90.80.9-1.01.70.41.3-0.3
Patch foraging water rate 24 sec2.23.13.91.51.9-1.82.01.91.9-1.2
Patch foraging water rate 6 sec0.30.51.11.00.8-0.51.00.00.5-0.2
Seeking ratio, delayed vs. immediate footshock0.30.41.0-0.30.20.21.0-0.01.0-0.7
Distance traveled before self-admin1.82.02.80.91.2-1.31.51.51.7-1.5
Distance traveled after self-admin1.21.32.00.81.1-1.41.11.21.2-1.1
Extensor digitorum longus weight1.35.112.9-3.6-2.72.6-1.9-1.5-1.21.2
Bone: elastic displacement0.20.30.8-0.0-0.40.3-0.6-0.4-0.60.9
Bone: elastic work0.91.11.8-0.5-1.00.8-1.4-0.9-1.31.3
Bone: endosteal estimation0.10.20.5-0.5-0.60.7-0.4-0.2-0.40.4
Bone: endosteal perimeter0.20.41.3-0.60.0-0.01.10.21.00.0
Epididymis fat weight4.39.914.13.73.8-3.72.63.32.6-2.0
Delta time in closed arm before/after self-admin0.10.10.50.1-0.10.1-0.3-0.2-0.70.6
Delta time in open arm before/after self-admin0.50.51.3-1.2-0.81.1-0.2-0.5-0.1-0.1
Diff in mean of infusions in LGA sessions0.70.82.2-0.5-0.70.4-1.2-1.5-0.90.5
Delay discount exponential model param1.81.92.91.61.5-1.70.51.21.0-1.7
Extinction: sum of active levers before priming0.20.20.60.70.2-0.3-0.4-0.1-0.2-0.5
Active lever presses in extinction session 60.40.41.60.80.10.10.4-0.70.11.2
Bone: final force1.42.33.7-0.6-1.31.3-1.6-1.6-1.91.9
Bone: final moment1.42.33.8-0.6-1.31.3-1.7-1.5-1.91.8
Food consumed during 24 hour testing period0.20.30.90.20.4-0.40.90.10.7-0.1
Glucose1.01.62.41.01.3-1.21.51.11.6-1.0
Heart weight3.95.58.12.52.8-2.32.32.32.0-2.1
Delay discount hyperbolic model param1.71.82.91.61.5-1.60.51.20.9-1.7
Intermittent access intake day 1-15 change0.60.61.71.30.9-0.80.80.30.6-0.4
Intermittent access intake escalation0.80.82.61.61.0-0.90.80.40.5-0.3
Intermittent access intake escalation 22.02.04.62.21.6-1.70.91.00.9-1.0
Intermitt. access day 1 inactive lever presses0.70.71.6-0.20.6-0.41.20.61.3-0.9
Intermitt. access day 15 inactive lever presses0.00.10.1-0.2-0.20.4-0.1-0.4-0.00.1
Intermitt. access escalation Index0.10.10.40.10.1-0.3-0.20.60.1-0.1
Intermittent access day 1 total infusions3.54.07.3-2.7-2.41.8-2.4-1.9-1.50.4
Intermittent access day 15 total infusions0.80.91.4-1.0-1.20.9-1.2-1.0-0.8-0.0
Intermittent access terminal intake (last 3 days)0.80.91.5-1.2-1.20.8-1.2-1.1-0.60.1
Intermittent access total infusions2.02.23.5-1.9-1.81.4-1.6-1.7-1.00.5
Intermittent access day 1 locomotion1.61.75.5-2.4-1.51.2-1.2-1.0-0.3-0.6
Intermittent access day 15 total locomotion1.11.24.4-2.1-1.41.0-0.5-0.70.00.3
Intermittent access total locomotion0.70.83.3-1.8-1.00.6-0.5-0.70.2-0.5
Intermittent access standard deviation0.40.40.70.60.6-0.40.80.50.8-0.8
Left kidney weight0.10.20.80.3-0.10.10.7-0.20.40.9
Right kidney weight0.82.22.71.61.5-1.61.61.51.6-0.8
Cocaine induced anxiety0.00.00.1-0.40.1-0.1-0.10.10.2-0.0
Post-drug Anxiety0.00.00.0-0.00.1-0.1-0.2-0.1-0.20.0
Baseline Anxiety0.10.10.30.1-0.20.3-0.1-0.0-0.40.5
Tail length1.03.25.91.31.7-1.42.41.62.2-1.5
Length with tail2.27.99.02.72.9-2.82.93.02.9-2.4
Length without tail0.40.91.21.01.1-1.11.01.11.0-0.2
Times rat made contact with spout1.82.14.1-1.9-1.51.60.6-1.3-0.02.0
Lifetime Intake2.62.94.3-1.9-2.11.7-2.0-1.7-1.30.7
Liver weight, left1.11.82.51.61.4-1.41.01.41.2-1.2
Liver weight, right5.38.811.43.43.4-3.42.62.82.7-2.4
Locomotor activity0.40.61.60.1-0.40.6-1.2-0.5-1.30.2
Locomotor testing distance0.60.91.6-0.8-0.91.2-1.2-0.7-1.30.3
Locomotor testing rearing0.20.30.8-0.9-0.40.6-0.40.2-0.1-0.7
Locomotion in novel chamber0.20.20.40.20.6-0.50.40.00.5-0.6
Locomotion in novel chamber post-restriction1.21.42.91.41.3-1.30.90.70.8-1.7
Fecal boli incidents, locomotor time 10.10.10.30.1-0.10.20.0-0.3-0.60.6
Change in fecal boli incidents, locomotor task7.57.110.52.42.7-2.62.33.22.6-2.7
Time >=10cm from walls, locomotor time 11.71.76.22.51.0-1.0-0.81.1-0.8-1.1
Bouts of movement, locomotor time 11.11.22.7-0.7-1.21.0-1.6-1.0-1.30.1
Total resting periods, locomotor time 11.11.22.6-0.5-1.21.2-1.6-0.9-1.50.3
Rest time, locomotor task time 10.30.31.00.5-0.30.6-0.7-0.1-1.00.1
Distance moved, locomotor task time 10.10.10.2-0.20.2-0.5-0.2-0.00.2-0.3
Vertical activity count, locomotor time 10.20.20.50.10.5-0.70.30.70.5-0.1
Time >=10cm from walls, locomotor time 21.31.42.21.31.5-1.21.01.30.8-1.0
Bouts of movement, locomotor time 21.51.73.81.91.3-1.40.41.60.4-1.2
Total resting periods, locomotor time 21.51.63.21.81.2-1.40.31.60.5-1.3
Rest time, locomotor task time 20.30.30.6-0.7-0.70.7-0.6-0.3-0.4-0.0
Distance moved, locomotor task time 20.10.10.20.00.4-0.50.10.10.3-0.1
Vertical activity count, locomotor time 20.20.30.60.10.5-0.40.70.10.40.8
Light reinforcement 12.13.910.1-3.2-2.42.2-1.6-1.6-1.00.5
Light reinforcement 21.52.13.2-1.4-1.61.3-1.8-1.5-1.40.9
Bone: marrow area0.10.20.5-0.5-0.60.7-0.3-0.1-0.30.3
Bone: maximum diameter0.40.71.9-1.4-1.00.8-0.2-1.1-0.20.7
Bone: maximum force0.20.41.20.3-0.30.2-1.1-0.3-1.00.6
Bone: maximum moment0.20.41.30.4-0.30.2-1.1-0.3-1.00.5
Mean time between licks in bursts0.30.41.51.20.5-0.6-0.40.5-0.4-0.0
Mean num. licks in bursts1.82.25.1-1.6-1.31.60.4-1.7-0.42.3
Cd content in liver0.20.20.60.80.6-0.50.40.50.2-0.1
Co content in liver1.92.33.4-1.6-1.81.6-1.0-1.7-1.31.3
Cu content in liver0.00.00.1-0.3-0.20.1-0.20.1-0.10.2
Fe content in liver0.10.20.60.20.00.40.4-0.1-0.20.8
K content in liver0.30.30.9-0.40.3-0.30.80.30.9-0.5
Mg content in liver0.70.73.0-1.7-0.81.00.1-0.50.20.0
Mn content in liver0.60.72.6-1.6-0.70.80.2-0.70.10.7
Na content in liver0.60.61.0-0.9-0.40.30.7-1.00.61.0
Rb content in liver0.81.01.9-1.4-1.21.3-0.6-0.9-0.60.8
Se content in liver0.20.20.50.10.3-0.10.50.40.6-0.7
Sr content in liver2.01.82.41.41.4-1.51.11.51.4-1.0
Zn content in liver0.60.71.6-0.10.5-0.41.00.91.3-1.0
Bone: minimum diameter0.00.10.3-0.0-0.00.30.20.30.10.6
Time in familiar zone, hab. session 10.10.10.4-0.10.20.20.30.60.1-0.2
Time in novel zone, hab. session 10.80.81.41.00.9-1.00.21.00.5-1.2
Total zone transitions, hab. session 10.20.30.60.20.6-0.40.80.30.6-0.6
Total locomotion distance, hab. session 10.40.61.40.20.7-0.41.20.51.0-0.8
Locomotion velocity, hab. session 10.30.41.00.00.5-0.41.00.21.0-0.6
Time in familiar zone, hab. session 22.22.23.2-1.4-1.61.8-1.3-1.3-1.51.6
Time in novel zone, hab. session 22.92.93.81.51.8-1.81.42.01.7-1.8
Total zone transitions, hab. session 20.30.40.8-0.6-0.70.9-0.5-0.6-0.80.4
Total locomotion distance, hab. session 20.10.20.3-0.10.10.20.50.50.5-0.5
Locomotion velocity, hab. session 20.00.10.2-0.3-0.10.40.20.20.2-0.3
Novel to familiar place preference ratio1.21.32.81.41.4-1.70.60.80.7-0.9
Novelty place preference1.21.32.81.51.4-1.70.50.70.6-0.9
Time in novel zone, NPP test1.21.32.61.51.4-1.60.40.80.5-1.0
Total zone transitions, NPP test0.20.30.9-1.0-0.70.7-0.3-0.3-0.2-0.4
Total locomotion distance, NPP test0.20.20.6-0.8-0.20.30.30.20.3-0.7
Locomotion velocity, NPP test0.30.51.6-1.3-0.80.80.0-0.60.1-0.0
Intraocular pressure0.71.03.20.9-0.10.0-1.80.1-1.7-0.2
Delta distance traveled before/after self-admin0.10.10.20.10.4-0.50.4-0.10.3-0.1
Delta ambulatory time before/after self-admin0.20.20.6-0.5-0.40.1-0.3-0.8-0.30.7
Parametrial fat weight0.40.82.51.60.9-0.9-0.20.7-0.1-0.9
Pavlov. Cond. lever latency1.11.42.21.21.3-1.50.71.10.9-1.3
Pavlov. Cond. magazine entry latency0.10.20.5-0.30.1-0.10.7-0.00.70.1
Pavlov. Cond. change in total contacts0.10.10.2-0.00.1-0.10.20.30.3-0.4
Pavlov. Cond. index score0.10.10.3-0.5-0.40.50.1-0.30.00.3
Pavlov. Cond. latency score0.10.10.2-0.5-0.30.40.1-0.20.00.3
Pavlov. Cond. lever contacts0.30.30.5-0.7-0.70.7-0.2-0.5-0.30.6
Pavlov. Cond. magazine entry number0.00.10.10.40.1-0.1-0.30.2-0.3-0.2
Pavlov. Cond. intertrial magazine entries1.01.22.1-0.5-1.11.3-1.2-1.0-1.41.0
Pavlov. Cond. lever-magazine prob. diff.0.20.20.5-0.7-0.60.60.0-0.5-0.10.5
Pavlov. Cond. response bias0.40.50.9-0.7-0.70.8-0.0-0.7-0.31.0
Pavlov. Cond. lever latency0.20.20.40.40.5-0.50.60.40.50.0
Pavlov. Cond. magazine entry latency0.70.81.6-0.6-0.90.8-1.3-1.0-0.90.5
Pavlov. Cond. change in total contacts0.10.10.50.1-0.1-0.2-0.50.1-0.2-0.7
Pavlov. Cond. index score0.30.40.7-0.4-0.70.5-0.8-0.6-0.60.1
Pavlov. Cond. latency score0.20.20.5-0.3-0.50.4-0.7-0.5-0.5-0.0
Pavlov. Cond. lever contacts0.00.00.2-0.1-0.1-0.0-0.00.10.1-0.5
Pavlov. Cond. magazine entry number0.30.40.90.70.7-0.40.90.70.50.1
Pavlov. Cond. intertrial magazine entries1.62.13.21.71.8-1.51.51.41.2-0.8
Pavlov. Cond. lever-magazine prob. diff.0.20.30.7-0.3-0.60.5-0.8-0.5-0.70.1
Pavlov. Cond. response bias0.30.40.7-0.8-0.80.6-0.8-0.7-0.5-0.1
Time in closed arm before self-admin1.41.62.81.01.2-1.41.31.11.7-1.0
Time in closed arm after self-admin2.52.64.31.21.6-2.11.71.41.9-1.0
Time in open arm before self-admin0.40.51.70.6-0.20.5-1.0-0.0-1.3-0.1
Time in open arm after self-admin1.82.03.2-1.1-1.51.8-1.7-1.2-1.60.2
Bone: periosteal estimation0.10.20.4-0.6-0.60.5-0.2-0.4-0.20.7
Bone: periosteal perimeter0.20.31.1-0.00.3-0.51.00.40.9-0.1
Bone: post-yield work0.10.20.8-0.20.00.1-0.10.60.2-0.9
Progressive ratio test 1 active lever presses0.90.92.3-1.5-1.00.5-1.0-1.0-0.1-0.9
Progressive ratio test 1 breakpoint0.80.92.5-1.6-1.00.4-0.9-0.80.0-1.0
Progressive ratio test 1 inactive lever presses0.60.62.4-1.5-1.00.7-0.5-0.70.10.0
Progressive ratio test 2 active lever presses0.70.71.4-1.0-0.90.3-1.2-1.1-0.5-0.1
Progressive ratio test 2 breakpoint0.70.81.7-1.1-1.00.5-1.2-1.3-0.50.2
Progressive ratio test 2 inactive lever presses0.50.61.1-0.9-0.90.7-0.8-1.0-0.40.3
Incentive Sensitization - Responses0.10.10.4-0.3-0.2-0.4-0.6-0.30.0-0.4
Incentive Sensitization - Breakpoint0.10.10.3-0.2-0.1-0.5-0.6-0.20.1-0.4
Sum of active levers in priming session hrs 5-60.60.61.2-0.2-0.50.5-0.7-1.0-0.81.1
Progressive ratio0.70.82.7-1.00.10.61.60.61.2-0.2
Food seeking constrained by brief footshock2.73.35.3-1.5-2.12.3-1.1-1.8-1.62.1
Seeking ratio, punishment vs. effort1.21.53.00.3-1.00.5-1.7-1.3-1.71.3
Retroperitoneal fat weight9.330.440.35.66.3-6.24.55.75.0-5.0
Reaction time number correct0.10.10.30.30.3-0.20.5-0.10.30.0
Reaction time mean minus median0.30.40.9-0.3-0.50.8-0.6-1.0-0.80.4
Reaction time mean minus median AUC0.30.41.00.80.00.1-0.9-0.8-1.00.2
Reaction time num false alarms0.30.51.60.5-0.20.0-1.30.2-1.1-0.4
Reaction time num false alarms AUC0.30.41.60.4-0.30.1-1.30.2-1.0-0.5
Reaction time trials correct on left0.10.10.30.30.3-0.20.5-0.10.30.0
Reaction time trials on left0.00.10.20.30.3-0.20.4-0.10.2-0.0
Reaction time mean0.30.41.01.00.3-0.2-0.9-0.1-0.8-0.5
Reaction time mean AUC0.30.41.31.10.5-0.4-0.50.1-0.5-0.8
Median of all reaction times0.40.61.51.20.5-0.4-0.90.2-0.8-0.8
Reaction time omissions0.60.82.31.50.6-0.2-0.90.5-0.8-1.0
Reaction time false alarm rate0.30.41.60.1-0.40.1-1.30.2-0.8-0.5
Reaction time premature initiation rate0.50.72.2-0.50.1-0.01.50.61.4-0.3
Reaction time premature initiations0.50.72.5-0.20.3-0.21.60.51.4-0.3
Std. dev. reaction times0.10.20.40.50.10.1-0.5-0.5-0.6-0.1
Reaction time trials completed0.00.10.20.30.3-0.20.4-0.10.2-0.0
Reaction time trials AUC0.00.00.10.00.00.00.2-0.30.00.2
Run reversals in cocaine runway, females0.20.20.5-0.20.4-0.70.60.40.70.2
Run reversals in cocaine runway, males0.00.00.2-0.2-0.0-0.40.00.10.30.2
Latency to leave start box in cocaine runway0.91.01.6-0.7-1.11.0-0.7-1.1-0.91.3
Latency to leave start box in cocaine runway, F1.82.02.7-1.1-1.61.6-1.2-1.4-1.31.5
Latency to leave start box in cocaine runway, M0.10.10.30.30.4-0.50.30.30.40.2
Std. dev. time between licks in bursts0.60.71.51.00.9-0.80.61.20.5-0.7
Total sessions with >9 infusions0.91.01.5-1.0-1.21.0-1.2-1.1-0.90.0
Short access day 1 total inactive lever presses0.40.41.4-1.2-0.60.4-0.1-0.40.5-0.8
Short access day 10 total inactive lever presses0.20.20.50.40.50.00.70.30.4-0.2
Short access day 1 total infusions1.51.63.6-1.4-1.41.1-1.9-1.0-1.10.1
Short access day 10 total infusions3.84.25.7-2.1-2.42.2-2.4-2.0-1.81.2
Short access total infusions2.62.95.5-1.5-1.91.7-2.3-1.5-1.70.8
Short access day 1 locomotion1.01.13.7-1.9-1.31.0-0.6-1.0-0.10.3
Short access day 10 total locomotion0.80.94.0-2.0-1.01.1-0.6-0.20.0-0.4
Short access total locomotion0.60.62.8-1.7-0.80.7-0.4-0.50.2-0.4
One hour access (0.3 mA shock)1.82.23.2-1.7-1.61.2-1.4-1.8-1.01.4
Compulsive drug intake0.30.30.60.70.8-0.80.70.10.40.1
One hour access (shock baseline)1.11.32.6-1.6-1.51.1-1.0-1.2-0.50.7
Social response proportion0.10.10.2-0.2-0.30.3-0.40.1-0.20.4
Social responses1.21.63.7-0.11.0-0.91.71.41.9-1.0
Social time0.10.10.3-0.5-0.20.40.10.20.10.3
Soleus weight1.13.18.8-3.0-2.32.1-1.0-1.2-0.70.8
Bone: stiffness0.20.31.01.00.5-0.6-0.40.5-0.3-0.2
Tibialis anterior weight1.86.113.1-3.6-2.92.6-2.6-1.9-1.80.7
Time to tail flick, vehicle, before self-admin3.13.27.52.72.0-1.71.41.81.2-1.1
Time to tail flick, vehicle, after self-admin3.94.211.00.81.9-1.33.31.32.8-1.6
Time to tail flick, test, before self-admin0.40.40.80.30.4-0.30.90.40.8-0.8
Time to tail flick, test, after self-admin4.85.08.81.01.9-1.62.92.13.0-2.4
Delta time to tail flick, vehicle, before/after SA0.30.30.8-0.9-0.20.40.7-0.30.5-0.1
Delta time to tail flick, test, before/after SA0.40.41.1-0.50.2-0.00.90.41.0-0.5
Tibia length2.05.77.92.12.4-2.62.52.42.8-1.7
Ambulatory time before self-admin2.02.03.10.91.2-1.51.21.51.7-1.8
Ambulatory time after self-admin1.61.73.20.61.2-1.51.71.11.8-0.8
Bone: tissue strength0.20.20.70.50.1-0.2-0.9-0.0-0.7-0.4
Total heroin consumption2.42.84.3-1.9-1.71.5-1.7-2.1-1.51.0
Bone: trabecular number5.07.89.8-2.6-2.92.9-2.5-2.9-2.73.1
Bone: trabecular spacing1.82.43.41.91.6-1.61.11.61.2-1.6
Bone: trabecular thickness0.60.81.1-0.9-0.80.7-1.0-0.8-0.81.0
Bone: trabecular tissue density0.10.10.3-0.4-0.30.20.1-0.50.00.5
Water consumed over 24 hours0.50.61.6-1.3-0.80.90.5-0.50.20.7
Number of responses in last shaping day1.61.62.41.01.2-1.01.31.41.3-1.6