LOC120102833

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	PL	intron excision ratio	chr5_31259983_31260576	0.12	0.09	6.8e-10	0.09	0.09	0.1	0.08	1.5e-09	7.2e-10	4.0e-11	1.8e-09
2	OFC	gene expression	LOC120102833	0.16	0.1	1.4e-03	0.1	0.09	0.03	0.08	2.8e-03	4.2e-03	6.6e-02	5.7e-03
3	NAcc	gene expression	LOC120102833	0.02	0.01	1.0e-03	0.02	0.02	0.01	0.01	6.7e-04	1.3e-03	5.1e-03	5.2e-03
4	PL	intron excision ratio	chr5_31260728_31264218	0.05	0.03	6.5e-07	0.06	0.05	0.05	0.05	4.6e-07	2.6e-06	7.9e-06	2.6e-06
5	Brain	gene expression	LOC120102833	0.13	0.07	4.6e-13	0.12	0.14	0.13	0.13	7.9e-11	4.8e-13	2.9e-12	5.2e-12
6	PL	gene expression	LOC120102833	0.18	0.07	0.0e+00	0.29	0.29	0.3	0.3	6.2e-32	2.3e-32	6.0e-33	9.7e-33
7	PL	intron excision ratio	chr5_31259557_31259912	0.11	0.06	5.6e-17	0.15	0.16	0.14	0.16	7.7e-16	8.7e-17	1.8e-15	1.3e-16
8	BLA	gene expression	LOC120102833	0.19	0.11	8.1e-07	0.08	0.09	0.09	0.08	3.2e-05	1.7e-05	1.8e-05	7.3e-05
9	IC	gene expression	LOC120102833	0.14	0.07	2.6e-06	0.05	0.09	0.1	0.09	3.5e-03	1.0e-04	8.8e-05	1.9e-04
10	pVTA	gene expression	LOC120102833	0.07	0.05	4.2e-05	0.03	0.03	0.04	0	9.2e-04	1.7e-03	2.6e-04	1.4e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10
Bone: apparent density	5.5	10.2	11.5	3.1	3.2	3.2	-2.9	-2.8	3.2	-3.3	-3.4	3.4	3.4
Area under the delay curve	1.9	3.0	4.0	-2.0	-1.6	-1.7	1.9	1.4	-1.6	1.8	1.9	-1.6	-1.5
BMI with tail	1.7	6.1	9.0	2.2	2.7	3.0	-2.2	-2.8	2.5	-2.4	-2.3	2.1	2.2
BMI without tail	1.0	5.4	10.7	2.2	2.8	3.3	-1.8	-3.1	2.5	-2.1	-2.1	1.1	1.2
Body weight	1.1	4.9	9.3	2.6	2.6	2.8	-2.1	-3.0	2.3	-2.0	-1.8	0.7	0.9
Weight adjusted by age	0.0	0.1	0.5	0.6	0.2	0.1	0.1	0.2	-0.1	0.3	0.2	-0.6	-0.7
Bone surface	2.9	5.8	7.6	2.2	2.8	2.7	-2.2	-2.2	2.4	-2.5	-2.5	2.2	2.3
Bone volume	3.3	6.5	8.0	2.5	2.8	2.8	-2.3	-2.3	2.6	-2.6	-2.7	2.4	2.5
Breakpoint value in progressive ratio session	0.1	0.2	0.4	0.1	0.4	0.6	0.7	-0.7	0.2	-0.1	-0.1	0.1	0.4
Number of licking bursts	0.3	0.9	2.2	0.3	0.0	-0.1	-1.5	-0.9	1.0	-1.0	-0.8	1.2	1.3
Context. condit. distance diff. score	2.4	3.0	6.1	1.8	1.3	1.2	-1.6	-1.2	1.5	-1.7	-1.7	2.5	2.3
Locomotion velocity, session 1	0.2	0.2	0.6	0.4	0.8	0.7	0.1	-0.4	0.1	0.2	0.1	-0.4	-0.4
Locomotion distance, session 1	0.5	0.6	1.3	-0.2	-0.2	-0.3	1.1	0.9	-0.8	1.0	0.8	-0.8	-0.9
Locomotion velocity, session 2	0.4	0.5	0.9	-0.8	-0.3	-0.6	0.7	0.9	-0.9	0.9	0.7	-0.5	-0.7
Locomotion distance, session 2	1.4	2.0	4.1	-0.8	-0.8	-1.2	2.0	1.6	-1.5	1.5	1.4	-1.5	-1.5
Locomotion velocity, session 3	0.8	0.9	2.6	0.9	0.4	0.3	-0.7	-0.5	0.9	-0.9	-0.9	1.6	1.4
Locomotion distance, session 3	0.5	0.5	1.1	0.9	0.8	0.7	-0.2	-0.3	0.6	-0.7	-0.8	1.0	0.8
Stereotopy head waving bouts, day 3	0.4	0.4	1.3	-1.0	-1.1	-1.2	0.1	0.3	-0.3	0.4	0.5	-0.1	-0.1
Stereotopy head waving duration, day 3	0.5	0.6	2.2	-0.9	-1.5	-1.3	0.1	0.3	-0.4	0.4	0.7	-0.4	-0.3
Locomotion velocity, session 7	2.9	3.2	4.2	2.0	1.7	1.3	-1.2	-1.4	1.9	-2.0	-2.0	2.0	2.0
Locomotion distance, session 7	0.4	0.5	1.3	0.9	0.5	-0.0	-0.2	0.3	0.4	-0.8	-0.9	1.1	1.1
Stereotopy head waving bouts, day 7	0.1	0.1	0.2	-0.3	-0.4	-0.4	-0.0	0.0	-0.1	0.2	0.2	-0.4	-0.4
Stereotopy head waving duration, day 7	0.1	0.1	0.3	0.1	0.1	0.3	-0.6	-0.5	0.4	-0.3	-0.3	-0.1	-0.1
Locomotion velocity, session 8	0.0	0.0	0.1	0.4	-0.2	-0.2	-0.2	0.1	0.0	0.1	-0.0	0.1	-0.1
Locomotion distance, session 8	0.1	0.1	0.3	0.5	0.1	-0.3	0.5	0.5	-0.2	0.2	0.1	0.3	0.2
Degree of sensitization distance	0.0	0.0	0.1	0.1	-0.2	-0.3	-0.1	0.3	-0.0	-0.2	-0.1	0.1	0.3
Degree of sensitization stereotypy	0.2	0.2	0.4	-0.4	-0.5	-0.4	0.3	0.2	-0.3	0.4	0.4	-0.6	-0.5
Conditioned locomotion	0.4	0.5	1.7	-0.1	-0.1	-0.1	0.1	0.3	-0.5	0.7	0.8	-1.3	-1.3
Cocaine response after cond. corrected	0.2	0.4	1.0	-0.9	-0.6	-0.6	0.2	0.3	-0.4	0.2	0.2	1.0	0.8
Cocaine response after cond. not corrected	0.3	0.4	2.2	-0.2	-0.4	-0.4	-0.2	-0.1	0.2	-0.4	-0.3	1.5	1.2
Cocaine response before conditioning	0.7	0.9	1.5	1.2	0.4	0.5	-1.0	-0.8	1.0	-1.2	-1.1	0.9	1.0
Saline control response	1.3	1.8	4.5	1.4	1.9	2.1	-0.8	-1.5	1.4	-0.9	-1.2	0.5	0.3
Bone: connectivity density	2.9	4.6	7.1	1.7	2.1	2.1	-1.8	-1.7	2.0	-2.2	-2.4	2.7	2.7
Bone: cortical apparent density	0.8	1.2	2.4	1.2	1.2	1.1	-0.7	-0.4	0.9	-1.0	-1.3	1.5	1.2
Bone: cortical area	1.2	2.0	4.5	2.1	1.5	1.2	-1.4	-1.1	1.3	-1.5	-1.4	1.1	1.3
Bone: cortical porosity	0.4	0.4	0.8	0.9	-0.8	-0.6	-0.7	-0.6	0.4	-0.3	0.1	-0.8	-0.7
Bone: cortical porosity	0.5	0.5	1.6	1.2	-0.5	-0.3	-1.0	-1.0	0.7	-0.7	-0.3	-0.4	-0.3
Bone: cortical thickness	0.8	1.3	1.9	-0.2	-1.0	-1.3	1.3	1.4	-1.2	1.0	1.1	-1.4	-1.2
Bone: cortical thickness	1.9	2.4	4.4	-1.0	-1.6	-1.5	1.5	2.1	-1.8	1.6	1.5	-1.3	-1.2
Bone: cortical tissue density	0.9	1.5	2.8	1.2	1.3	1.3	-0.8	-0.5	1.0	-1.1	-1.4	1.7	1.3
Condit. Reinf. active minus inactive responses	1.5	1.7	3.1	-0.9	-1.0	-1.0	1.4	0.9	-1.3	1.4	1.5	-1.7	-1.7
Condit. Reinf. active-inactive response ratio	0.6	0.6	1.0	-0.6	-0.7	-0.4	0.8	0.6	-0.8	0.9	0.8	-0.9	-1.0
Condit. Reinf. active responses	2.7	3.5	6.4	-1.4	-1.2	-1.3	1.9	1.5	-1.8	2.0	1.9	-2.5	-2.5
Condit. Reinf. inactive responses	0.4	0.6	1.6	-0.5	-0.2	-0.6	0.6	0.5	-0.6	0.8	0.8	-1.2	-1.1
Incentive salience index mean	2.5	3.2	6.2	-1.3	-1.5	-1.5	1.8	1.0	-1.6	1.9	2.0	-2.5	-2.4
Condit. Reinf. lever presses	1.5	2.3	5.2	-1.1	-1.1	-1.3	1.4	0.6	-1.3	1.6	1.8	-2.3	-2.1
Condit. Reinf. active minus inactive responses	0.6	0.9	1.5	-0.9	-0.7	-0.7	1.2	0.5	-0.9	1.1	1.2	-1.2	-1.0
Condit. Reinf. active-inactive response ratio	0.4	0.6	1.0	-1.0	-0.9	-0.8	0.9	0.5	-0.7	0.8	1.0	-0.7	-0.5
Condit. Reinf. active responses	0.3	0.5	1.5	-0.3	0.1	0.1	1.0	-0.1	-0.4	0.7	0.7	-1.2	-1.0
Condit. Reinf. inactive responses	0.2	0.2	0.6	0.0	0.7	0.6	0.6	-0.2	-0.2	0.3	0.1	-0.8	-0.7
Condit. Reinf. lever presses	0.2	0.2	0.9	0.6	0.9	0.9	0.2	-0.4	0.3	-0.2	-0.3	0.1	0.1
Condit. Reinf. lever reinforcers received	0.2	0.3	1.0	-0.3	0.0	0.1	0.7	-0.2	-0.3	0.6	0.7	-1.0	-0.8
Conditioned reinforcement - actives	1.8	7.1	9.9	-3.1	-3.1	-3.2	2.1	2.2	-2.7	2.6	2.8	-2.3	-2.3
Conditioned reinforcement - inactives	0.4	1.0	3.6	-1.9	-1.0	-1.0	0.1	0.8	-1.0	0.9	0.9	-0.6	-0.6
Conditioned locomotion	5.5	8.1	11.0	-3.3	-2.9	-3.0	2.4	3.1	-2.9	2.8	2.7	-2.6	-2.6
Patch foraging indifference point 0 sec	0.6	1.8	4.9	1.9	2.2	2.2	-0.4	-0.9	1.0	-1.0	-1.2	0.2	0.3
Patch foraging indifference point AUC	0.0	0.1	0.4	-0.5	0.4	0.4	0.2	-0.0	-0.1	0.1	0.0	-0.6	-0.3
Delay disc. indifference point, 0s delay	0.5	0.6	0.9	0.7	1.0	0.9	-0.4	-0.9	0.9	-0.7	-0.7	0.7	0.5
Delay disc. indifference point, 16s delay	0.1	0.2	0.5	-0.7	-0.7	-0.7	-0.0	-0.1	-0.2	0.2	0.4	0.2	0.3
Delay disc. indifference point, 2s delay	1.2	1.3	2.8	-1.1	-0.9	-1.2	1.7	1.0	-1.0	1.1	1.0	-1.1	-1.2
Delay disc. indifference point, 24s delay	1.1	1.7	3.1	-1.5	-1.7	-1.8	0.8	0.9	-1.2	1.2	1.4	-1.1	-1.1
Delay disc. indifference point, 4s delay	2.0	2.1	3.6	-1.8	-0.9	-1.0	1.4	1.1	-1.3	1.5	1.4	-1.8	-1.9
Delay disc. indifference point, 8s delay	3.2	5.4	7.4	-1.9	-2.0	-2.0	2.7	2.1	-2.3	2.6	2.5	-2.5	-2.4
Indifference point function ln k	0.2	0.6	1.7	0.7	0.0	-0.2	-0.7	-0.5	0.6	-0.7	-0.6	1.3	1.2
Indifference point function log k	0.2	0.6	1.7	0.7	0.0	-0.2	-0.7	-0.5	0.6	-0.7	-0.6	1.3	1.2
Patch foraging total patch changes 0 sec	0.7	2.2	5.8	2.0	2.4	2.3	-0.5	-1.0	1.1	-1.1	-1.4	0.4	0.5
Patch foraging total patch changes 12 sec	0.9	1.2	3.8	1.3	1.9	1.9	-0.1	-0.5	0.8	-0.9	-1.2	-0.2	-0.2
Patch foraging total patch changes 18 sec	0.3	0.6	1.9	0.9	1.2	1.4	0.1	-0.6	0.5	-0.3	-0.4	-0.8	-0.7
Patch foraging total patch changes 24 sec	0.2	0.6	1.9	0.5	0.6	0.5	1.4	0.5	-0.3	0.4	0.2	-1.3	-1.2
Patch foraging total patch changes 6 sec	0.3	0.6	2.1	0.5	1.4	1.4	0.0	-0.8	0.3	-0.2	-0.3	-0.6	-0.3
Patch foraging time to switch 0 sec	0.4	1.6	2.7	-0.7	-1.0	-0.8	1.3	1.3	-1.2	1.4	1.3	-1.5	-1.7
Patch foraging water rate 0 sec	0.6	2.4	2.9	1.2	1.6	1.4	-1.4	-1.7	1.6	-1.7	-1.7	1.5	1.5
Patch foraging water rate 12 sec	0.3	1.0	1.8	1.1	0.6	0.5	-1.3	-1.2	1.2	-1.1	-0.8	1.0	0.9
Patch foraging water rate 18 sec	0.5	1.2	2.1	1.5	0.6	0.6	-1.1	-1.0	1.1	-1.2	-1.1	1.3	1.1
Patch foraging water rate 24 sec	0.1	0.2	0.6	0.7	0.1	0.0	-0.8	-0.6	0.5	-0.5	-0.3	0.2	0.1
Patch foraging water rate 6 sec	1.3	1.9	4.3	2.1	0.9	0.8	-1.1	-1.1	1.5	-1.6	-1.5	1.5	1.4
Seeking ratio, delayed vs. immediate footshock	0.7	0.9	1.5	0.6	0.8	0.8	-1.1	-0.9	1.1	-1.1	-1.0	0.9	1.2
Distance traveled before self-admin	0.2	0.5	1.2	-1.1	-0.9	-0.8	0.8	0.8	-0.7	0.7	0.6	-0.0	0.1
Distance traveled after self-admin	0.3	0.6	2.3	-1.5	-1.0	-0.9	0.8	0.2	-0.5	0.7	0.7	0.1	0.2
Extensor digitorum longus weight	0.2	0.7	1.8	1.2	1.3	1.4	-0.6	-0.5	0.5	-0.7	-0.7	0.3	0.5
Bone: elastic displacement	1.6	2.0	3.0	-1.5	-1.7	-1.7	1.2	1.2	-1.3	1.5	1.5	-1.1	-1.2
Bone: elastic work	0.9	1.2	1.6	-0.7	-0.9	-1.1	1.2	1.3	-1.2	1.1	1.0	-1.1	-1.1
Bone: endosteal estimation	5.2	12.8	15.7	3.4	3.8	4.0	-3.8	-3.4	3.6	-3.6	-3.6	3.3	3.2
Bone: endosteal perimeter	4.3	10.6	13.5	3.1	2.9	2.9	-3.7	-2.9	3.2	-3.3	-3.3	3.5	3.5
Epididymis fat weight	0.2	1.0	2.6	1.6	0.9	1.1	-1.0	-1.2	0.9	-0.8	-0.7	0.7	0.6
Delta time in closed arm before/after self-admin	0.4	0.4	0.7	0.8	0.8	0.8	-0.7	-0.5	0.7	-0.6	-0.6	0.2	0.4
Delta time in open arm before/after self-admin	0.2	0.2	1.0	0.1	0.4	0.3	-0.5	-1.0	0.6	-0.4	-0.2	0.3	0.2
Diff in mean of infusions in LGA sessions	2.1	3.7	4.7	2.1	2.1	2.2	-1.5	-2.1	2.1	-2.0	-2.0	1.5	1.7
Delay discount exponential model param	2.7	3.7	4.9	2.2	1.7	1.9	-2.0	-1.6	1.8	-2.0	-2.0	1.9	1.8
Extinction: sum of active levers before priming	5.2	7.9	9.3	3.0	2.9	3.0	-2.7	-2.9	3.0	-3.0	-2.9	2.1	2.4
Active lever presses in extinction session 6	2.9	2.9	4.4	2.1	1.8	1.8	-1.0	-1.3	1.7	-1.8	-1.9	1.7	1.7
Bone: final force	1.3	2.1	5.5	2.3	1.7	1.5	-1.2	-1.0	1.4	-1.5	-1.4	0.9	1.0
Bone: final moment	1.4	2.3	6.3	2.5	1.8	1.6	-1.2	-1.1	1.4	-1.5	-1.5	0.8	0.9
Food consumed during 24 hour testing period	2.0	4.0	5.0	1.9	2.2	2.2	-1.6	-2.0	2.0	-1.9	-2.0	2.0	2.0
Glucose	0.6	1.0	2.5	1.6	0.7	0.7	-1.3	-1.5	1.1	-0.9	-0.5	0.4	0.3
Heart weight	0.1	0.1	0.2	0.1	-0.5	-0.2	0.4	0.5	-0.3	0.2	0.1	-0.2	-0.2
Delay discount hyperbolic model param	3.2	4.1	5.3	2.3	1.8	1.9	-2.2	-1.7	2.0	-2.2	-2.1	2.1	2.0
Intermittent access intake day 1-15 change	0.1	0.7	1.5	-0.5	-1.0	-1.2	0.2	0.8	-0.8	0.7	0.9	-1.0	-1.1
Intermittent access intake escalation	0.1	0.4	1.3	-0.5	-0.9	-1.1	-0.2	0.6	-0.6	0.4	0.6	-0.5	-0.6
Intermittent access intake escalation 2	0.1	0.2	0.7	-0.2	-0.7	-0.9	-0.6	0.3	-0.1	-0.1	0.1	0.4	0.1
Intermitt. access day 1 inactive lever presses	0.0	0.4	1.4	-1.2	-0.7	-0.8	0.4	0.3	-0.6	0.5	0.6	-0.2	0.1
Intermitt. access day 15 inactive lever presses	0.1	0.7	2.6	-1.6	-0.9	-1.0	0.5	0.9	-0.8	0.7	0.6	-0.2	-0.4
Intermitt. access escalation Index	0.8	2.5	6.8	2.6	2.1	2.2	-0.8	-1.1	1.7	-1.5	-1.6	0.4	0.2
Intermittent access day 1 total infusions	0.2	0.7	1.6	-0.7	-0.6	-0.5	1.3	0.9	-0.9	0.7	0.6	-0.9	-1.0
Intermittent access day 15 total infusions	0.3	0.7	1.2	-0.8	-0.9	-1.0	0.6	1.1	-0.9	0.6	0.6	-0.8	-1.0
Intermittent access terminal intake (last 3 days)	0.3	0.5	1.0	-1.0	-0.9	-0.9	0.6	1.0	-0.8	0.4	0.4	-0.2	-0.4
Intermittent access total infusions	1.1	1.3	1.8	-1.0	-1.1	-1.1	1.2	1.3	-1.2	1.0	0.9	-1.1	-1.2
Intermittent access day 1 locomotion	1.7	3.1	4.3	-2.1	-1.7	-1.7	2.0	1.7	-1.8	1.7	1.6	-1.8	-1.6
Intermittent access day 15 total locomotion	2.2	8.6	10.5	-3.2	-2.7	-2.8	2.9	2.8	-3.0	3.0	2.9	-3.1	-2.9
Intermittent access total locomotion	5.9	7.1	9.5	-3.1	-2.5	-2.5	2.7	2.6	-2.8	2.6	2.5	-2.6	-2.5
Intermittent access standard deviation	1.0	5.5	6.8	-2.1	-2.6	-2.6	1.8	2.2	-2.6	2.3	2.6	-2.2	-2.3
Left kidney weight	0.8	6.4	9.0	2.4	3.0	3.0	-2.8	-3.0	2.6	-2.5	-2.4	1.5	1.6
Right kidney weight	1.0	7.3	10.4	2.8	3.1	3.1	-2.7	-3.2	2.9	-2.8	-2.6	1.5	1.7
Cocaine induced anxiety	0.1	0.3	0.9	-0.4	0.1	-0.1	0.7	1.0	-0.5	0.5	0.2	-0.3	-0.6
Post-drug Anxiety	3.3	3.7	5.5	-2.1	-1.6	-1.7	2.3	2.1	-1.9	2.1	1.8	-1.6	-1.9
Baseline Anxiety	0.6	0.9	1.9	-1.1	-1.4	-1.3	0.9	0.8	-0.8	0.9	1.0	-0.7	-0.4
Tail length	0.1	0.4	1.2	0.6	0.6	0.7	-0.2	-1.1	0.5	-0.2	-0.0	-0.9	-0.8
Length with tail	0.3	1.3	3.2	1.8	1.4	1.4	-0.8	-1.5	1.0	-0.9	-0.7	-0.5	-0.3
Length without tail	0.0	0.2	0.7	0.8	0.2	0.1	-0.1	-0.4	0.1	-0.1	0.0	-0.6	-0.4
Times rat made contact with spout	1.9	2.2	4.5	0.8	1.3	1.4	-2.1	-1.8	1.8	-1.4	-1.4	1.3	1.1
Lifetime Intake	1.2	1.5	1.9	-1.2	-1.1	-1.1	1.4	1.3	-1.3	1.2	1.1	-1.2	-1.4
Liver weight, left	0.7	1.3	3.1	1.4	1.4	1.5	-0.5	-1.8	1.2	-0.9	-0.8	-0.3	-0.0
Liver weight, right	2.0	3.4	9.4	1.1	1.9	1.9	-1.8	-3.1	2.1	-1.8	-1.5	1.1	1.3
Locomotor activity	0.8	1.2	1.9	0.5	1.3	1.3	-0.8	-1.1	1.0	-1.0	-1.2	1.4	1.2
Locomotor testing distance	1.0	2.3	3.8	0.9	1.3	1.3	-1.6	-1.4	1.6	-1.7	-1.7	1.9	1.7
Locomotor testing rearing	0.0	0.1	0.3	0.3	-0.1	-0.2	0.1	0.1	0.3	-0.4	-0.4	0.5	0.2
Locomotion in novel chamber	2.5	3.4	4.5	1.2	1.8	1.5	-2.0	-2.0	2.1	-1.8	-1.7	2.1	2.0
Locomotion in novel chamber post-restriction	0.3	0.9	1.4	-0.9	-0.8	-0.8	0.8	0.9	-0.8	1.0	0.9	-1.2	-1.1
Fecal boli incidents, locomotor time 1	0.0	0.0	0.1	-0.3	0.3	0.3	-0.1	-0.1	0.2	-0.1	-0.2	0.1	0.2
Change in fecal boli incidents, locomotor task	1.8	1.9	2.7	-1.5	-1.3	-1.2	1.2	1.2	-1.4	1.4	1.5	-1.6	-1.4
Time >=10cm from walls, locomotor time 1	0.2	0.2	0.6	-0.4	-0.8	-0.7	0.5	-0.1	-0.3	0.3	0.5	0.1	0.1
Bouts of movement, locomotor time 1	1.1	1.4	3.2	-1.4	-0.6	-0.4	1.0	0.2	-0.8	1.4	1.4	-1.8	-1.7
Total resting periods, locomotor time 1	0.9	1.0	2.8	-1.4	-0.2	-0.1	0.8	-0.0	-0.5	1.1	1.1	-1.7	-1.6
Rest time, locomotor task time 1	0.3	0.4	1.1	-0.1	0.8	0.9	-1.0	-0.8	0.7	-0.4	-0.5	-0.6	-0.4
Distance moved, locomotor task time 1	0.1	0.4	1.6	0.7	-0.3	-0.6	-0.0	0.4	-0.1	-0.4	-0.2	1.1	1.3
Vertical activity count, locomotor time 1	0.0	0.3	0.5	0.2	-0.7	-0.6	0.6	0.6	-0.4	0.1	0.2	0.7	0.7
Time >=10cm from walls, locomotor time 2	0.2	0.5	0.9	-0.2	-0.7	-0.5	0.9	0.9	-0.9	0.7	0.6	-0.6	-0.5
Bouts of movement, locomotor time 2	0.4	1.4	3.0	-1.1	-0.3	-0.3	1.5	0.6	-0.8	1.4	1.1	-1.7	-1.7
Total resting periods, locomotor time 2	0.2	0.9	2.5	-1.0	-0.0	0.0	1.1	0.2	-0.6	1.1	0.9	-1.6	-1.6
Rest time, locomotor task time 2	0.1	0.2	0.7	-0.9	0.2	0.2	-0.6	-0.3	0.1	0.2	0.1	-0.5	-0.6
Distance moved, locomotor task time 2	0.2	0.3	0.7	0.8	-0.6	-0.8	0.3	0.5	-0.2	-0.2	0.0	0.6	0.7
Vertical activity count, locomotor time 2	0.1	0.2	0.5	0.5	-0.4	-0.4	0.5	0.7	-0.2	-0.1	-0.1	0.6	0.7
Light reinforcement 1	0.8	3.4	5.7	2.4	2.1	2.1	-1.9	-1.4	1.8	-1.9	-2.0	1.4	1.2
Light reinforcement 2	0.6	1.5	4.0	-0.8	-0.6	-0.6	1.1	0.9	-1.0	1.3	1.1	-1.8	-2.0
Bone: marrow area	5.4	13.3	16.1	3.5	3.9	4.0	-3.9	-3.4	3.6	-3.6	-3.7	3.4	3.4
Bone: maximum diameter	5.5	11.1	15.4	3.9	3.2	3.1	-3.6	-3.2	3.2	-3.4	-3.3	3.1	3.3
Bone: maximum force	1.2	2.4	5.9	2.4	1.7	1.5	-1.3	-0.9	1.4	-1.6	-1.6	1.3	1.3
Bone: maximum moment	1.3	2.5	6.7	2.6	1.8	1.6	-1.3	-0.9	1.4	-1.6	-1.7	1.1	1.2
Mean time between licks in bursts	0.3	1.9	3.6	-0.8	-1.3	-1.4	1.2	1.2	-1.5	1.3	1.4	-1.9	-1.6
Mean num. licks in bursts	0.1	0.2	1.2	0.4	0.9	1.1	0.0	-0.2	0.2	0.1	-0.2	-0.2	-0.4
Cd content in liver	1.7	1.9	2.6	1.3	1.2	1.1	-1.3	-1.6	1.5	-1.5	-1.4	1.4	1.3
Co content in liver	0.4	0.4	1.4	1.2	0.9	1.0	0.0	-0.4	0.5	-0.5	-0.6	-0.0	0.1
Cu content in liver	1.9	2.3	3.3	-1.8	-1.6	-1.6	1.3	1.2	-1.4	1.5	1.5	-1.6	-1.5
Fe content in liver	0.5	0.6	0.9	-0.9	-0.7	-0.7	0.6	0.5	-0.8	0.9	1.0	-0.5	-0.7
K content in liver	1.4	1.3	3.8	-0.5	-0.6	-0.6	0.8	0.8	-1.0	1.3	1.2	-1.9	-1.9
Mg content in liver	0.2	0.2	0.8	0.3	0.1	0.2	-0.1	0.3	-0.3	0.4	0.2	-0.8	-0.9
Mn content in liver	4.4	5.0	6.8	-1.7	-2.3	-2.3	2.1	2.4	-2.2	2.1	2.0	-2.6	-2.5
Na content in liver	0.3	0.3	0.9	0.1	0.7	0.7	0.0	0.2	-0.4	0.6	0.3	-0.9	-1.0
Rb content in liver	0.0	0.0	0.1	-0.2	-0.2	-0.1	-0.0	0.3	0.0	-0.1	-0.2	-0.1	-0.2
Se content in liver	0.4	0.5	1.1	-1.0	-0.8	-0.7	0.5	0.4	-0.7	0.8	0.7	-0.7	-0.7
Sr content in liver	0.2	0.2	0.3	0.3	0.1	0.1	-0.6	-0.5	0.4	-0.4	-0.3	0.5	0.5
Zn content in liver	0.4	0.5	1.3	0.6	0.5	0.5	-1.1	-0.4	0.7	-0.8	-0.8	0.8	0.7
Bone: minimum diameter	2.2	4.2	5.7	2.3	1.8	1.6	-2.4	-1.8	2.1	-2.2	-2.1	2.0	2.2
Time in familiar zone, hab. session 1	2.3	2.6	3.1	1.6	1.8	1.7	-1.7	-1.3	1.5	-1.6	-1.6	1.7	1.5
Time in novel zone, hab. session 1	0.0	0.0	0.1	0.0	-0.1	0.0	0.2	0.0	-0.0	-0.0	-0.0	-0.2	-0.1
Total zone transitions, hab. session 1	0.1	0.1	0.4	-0.1	0.3	0.2	0.5	0.7	-0.0	0.0	-0.3	0.3	-0.0
Total locomotion distance, hab. session 1	0.8	1.1	3.0	-1.3	-0.9	-1.2	1.6	1.7	-1.0	0.7	0.4	0.1	-0.0
Locomotion velocity, hab. session 1	1.7	2.4	5.1	-1.8	-1.4	-1.7	2.1	2.3	-1.6	1.3	0.9	-0.6	-0.8
Time in familiar zone, hab. session 2	0.2	0.2	0.7	0.8	0.7	0.8	-0.4	-0.3	0.2	-0.1	-0.1	-0.3	-0.4
Time in novel zone, hab. session 2	0.3	0.3	1.0	0.0	0.1	-0.0	-0.4	-0.1	0.4	-0.6	-0.6	1.0	1.0
Total zone transitions, hab. session 2	0.9	1.2	2.1	-0.5	-0.7	-0.7	1.3	1.1	-1.1	1.2	1.1	-1.5	-1.4
Total locomotion distance, hab. session 2	3.0	4.0	5.8	-1.9	-2.0	-2.1	2.4	2.3	-2.2	2.0	1.8	-1.5	-1.5
Locomotion velocity, hab. session 2	2.8	3.8	5.7	-1.9	-2.0	-2.1	2.4	2.2	-2.1	1.9	1.7	-1.5	-1.5
Novel to familiar place preference ratio	0.1	0.1	0.3	-0.2	-0.3	-0.2	0.5	0.5	-0.6	0.4	0.4	-0.3	-0.2
Novelty place preference	0.0	0.0	0.1	0.0	-0.1	0.1	0.2	0.2	-0.2	0.0	0.0	0.0	0.1
Time in novel zone, NPP test	0.1	0.1	0.2	0.4	0.3	0.5	-0.2	-0.2	0.1	-0.2	-0.2	0.2	0.3
Total zone transitions, NPP test	0.9	1.3	3.0	-0.6	-0.6	-0.6	1.2	0.9	-0.9	1.2	1.1	-1.7	-1.7
Total locomotion distance, NPP test	2.6	3.6	6.3	-1.8	-1.5	-1.7	2.5	2.0	-1.8	1.9	1.7	-1.9	-1.9
Locomotion velocity, NPP test	4.0	5.7	9.1	-2.4	-2.1	-2.2	3.0	2.6	-2.3	2.4	2.2	-2.3	-2.3
Intraocular pressure	0.5	0.8	1.9	0.5	0.8	0.7	-0.3	0.5	0.5	-0.9	-1.3	1.4	1.0
Delta distance traveled before/after self-admin	0.1	0.1	0.5	-0.4	0.2	0.1	-0.4	-0.7	0.3	-0.3	-0.1	0.2	0.3
Delta ambulatory time before/after self-admin	0.0	0.0	0.2	-0.4	0.1	0.0	0.1	-0.3	-0.0	0.1	0.2	-0.2	-0.2
Parametrial fat weight	0.1	0.2	0.5	0.7	0.4	0.6	-0.6	-0.7	0.5	-0.5	-0.4	0.0	0.1
Pavlov. Cond. lever latency	0.3	0.4	0.8	-0.9	-0.7	-0.6	0.7	0.8	-0.6	0.6	0.5	0.1	-0.1
Pavlov. Cond. magazine entry latency	0.7	0.9	2.1	0.9	1.4	1.3	-0.9	-1.1	0.8	-0.7	-0.8	0.5	0.5
Pavlov. Cond. change in total contacts	0.6	0.6	1.8	0.9	1.4	1.0	-0.7	-0.7	0.7	-0.6	-0.8	0.1	0.0
Pavlov. Cond. index score	0.8	1.0	1.7	1.1	1.3	1.1	-1.1	-1.2	1.0	-1.0	-0.9	0.4	0.5
Pavlov. Cond. latency score	1.1	1.4	2.0	1.2	1.4	1.2	-1.3	-1.4	1.2	-1.2	-1.1	0.7	0.8
Pavlov. Cond. lever contacts	0.6	0.7	1.0	1.0	1.0	0.8	-1.0	-1.0	0.9	-0.9	-0.8	0.2	0.2
Pavlov. Cond. magazine entry number	0.3	0.3	0.8	-0.3	-0.9	-0.8	0.7	0.8	-0.5	0.4	0.5	-0.3	-0.3
Pavlov. Cond. intertrial magazine entries	1.6	1.9	4.0	-1.2	-0.8	-0.9	1.6	1.0	-1.1	1.5	1.4	-2.0	-1.9
Pavlov. Cond. lever-magazine prob. diff.	0.6	0.7	1.4	1.0	1.2	1.0	-0.8	-1.1	0.8	-0.7	-0.7	0.2	0.2
Pavlov. Cond. response bias	0.1	0.2	0.5	0.4	0.7	0.6	-0.3	-0.5	0.2	-0.1	-0.2	-0.3	-0.3
Pavlov. Cond. lever latency	0.9	1.2	2.2	-1.4	-1.5	-1.5	0.4	0.8	-1.0	1.0	1.2	-0.9	-0.8
Pavlov. Cond. magazine entry latency	0.2	0.3	0.6	0.7	0.4	0.5	-0.1	-0.4	0.3	-0.4	-0.4	0.7	0.8
Pavlov. Cond. change in total contacts	0.4	0.9	1.4	1.2	0.9	0.9	-0.6	-0.8	0.9	-0.9	-0.9	1.2	1.0
Pavlov. Cond. index score	0.5	0.8	1.7	1.3	1.1	1.2	-0.3	-0.8	0.9	-0.8	-0.9	0.8	0.7
Pavlov. Cond. latency score	0.2	0.4	0.9	1.0	0.8	0.9	0.1	-0.5	0.6	-0.5	-0.6	0.5	0.5
Pavlov. Cond. lever contacts	1.3	1.9	3.3	1.8	1.7	1.8	-0.7	-1.1	1.3	-1.3	-1.4	1.1	1.0
Pavlov. Cond. magazine entry number	0.7	0.9	1.5	-1.2	-1.0	-1.1	0.4	0.9	-0.9	0.9	0.9	-1.0	-1.0
Pavlov. Cond. intertrial magazine entries	0.5	1.2	2.5	-1.4	-0.5	-0.7	0.9	0.7	-0.9	1.2	1.1	-1.6	-1.5
Pavlov. Cond. lever-magazine prob. diff.	0.6	0.8	1.4	1.2	1.1	1.2	-0.3	-0.8	0.9	-0.8	-0.9	0.8	0.8
Pavlov. Cond. response bias	1.1	1.5	2.5	1.6	1.3	1.5	-0.7	-1.0	1.2	-1.2	-1.3	1.1	1.1
Time in closed arm before self-admin	0.2	0.3	1.1	-0.6	-0.7	-0.4	1.1	0.4	-0.5	0.3	0.3	0.2	0.1
Time in closed arm after self-admin	0.1	0.2	0.5	-0.4	-0.0	0.2	0.7	0.2	-0.3	0.4	0.3	-0.6	-0.5
Time in open arm before self-admin	0.4	0.5	1.0	-0.5	-0.6	-0.7	0.1	1.0	-0.8	0.7	0.6	-0.7	-0.6
Time in open arm after self-admin	0.1	0.1	0.6	-0.1	0.0	-0.2	-0.8	-0.2	0.1	-0.1	0.0	0.1	0.1
Bone: periosteal estimation	4.7	11.3	14.3	3.8	3.6	3.5	-3.5	-3.0	3.3	-3.4	-3.4	2.9	3.0
Bone: periosteal perimeter	3.5	7.0	8.1	2.9	2.5	2.4	-2.8	-2.2	2.6	-2.7	-2.8	2.7	2.7
Bone: post-yield work	1.5	2.6	6.7	2.6	1.9	1.9	-1.2	-0.9	1.4	-1.6	-1.6	1.2	1.3
Progressive ratio test 1 active lever presses	0.7	1.3	2.1	-1.0	-0.9	-0.9	1.5	1.1	-1.0	1.1	1.0	-1.3	-1.3
Progressive ratio test 1 breakpoint	0.7	1.2	2.1	-1.0	-0.9	-0.9	1.5	1.2	-1.0	1.0	0.9	-1.2	-1.2
Progressive ratio test 1 inactive lever presses	1.2	3.1	5.7	-2.4	-1.7	-1.8	1.6	1.8	-1.8	1.7	1.6	-1.4	-1.5
Progressive ratio test 2 active lever presses	1.6	2.3	2.8	-1.7	-1.6	-1.6	1.6	1.2	-1.4	1.4	1.4	-1.7	-1.6
Progressive ratio test 2 breakpoint	1.7	2.1	2.7	-1.7	-1.6	-1.6	1.5	1.2	-1.4	1.3	1.4	-1.6	-1.5
Progressive ratio test 2 inactive lever presses	0.5	1.7	2.5	-1.6	-1.3	-1.4	1.2	1.3	-1.3	1.1	1.1	-1.4	-1.4
Incentive Sensitization - Responses	0.3	0.8	1.9	-1.4	-1.0	-1.0	0.8	0.4	-0.8	0.7	0.9	-0.9	-0.7
Incentive Sensitization - Breakpoint	0.5	1.1	2.3	-1.5	-1.2	-1.2	0.9	0.5	-1.0	0.9	1.1	-1.1	-0.9
Sum of active levers in priming session hrs 5-6	0.2	0.2	0.5	0.4	-0.7	-0.7	0.6	0.4	-0.4	0.2	0.4	-0.4	0.1
Progressive ratio	0.3	0.8	1.7	0.2	1.0	1.0	-0.1	-0.9	0.7	-0.7	-0.8	1.3	1.2
Food seeking constrained by brief footshock	0.2	0.2	0.7	-0.1	-0.4	-0.4	0.7	0.6	-0.3	0.2	0.2	-0.6	-0.9
Seeking ratio, punishment vs. effort	0.6	1.4	2.8	-0.6	-1.6	-1.7	0.6	1.4	-0.9	0.8	0.9	-1.4	-1.4
Retroperitoneal fat weight	0.1	0.4	0.8	-0.5	-0.9	-0.7	0.5	0.4	-0.5	0.5	0.6	-0.7	-0.9
Reaction time number correct	5.0	17.7	26.7	4.3	5.1	4.8	-4.6	-5.2	4.6	-4.1	-3.8	2.2	2.3
Reaction time mean minus median	0.1	0.8	1.6	-0.8	-1.1	-0.8	1.3	0.9	-1.0	0.8	0.8	-0.6	-0.5
Reaction time mean minus median AUC	0.1	0.9	1.6	-0.6	-0.9	-0.8	1.3	0.9	-1.0	1.0	1.0	-1.1	-0.9
Reaction time num false alarms	0.3	0.5	1.3	1.0	0.8	0.9	-1.1	-0.9	0.7	-0.6	-0.5	0.0	0.1
Reaction time num false alarms AUC	0.6	1.5	3.1	1.7	1.4	1.4	-1.5	-1.4	1.2	-1.0	-0.9	0.3	0.3
Reaction time trials correct on left	5.0	17.7	26.7	4.3	5.1	4.8	-4.6	-5.2	4.6	-4.1	-3.8	2.2	2.3
Reaction time trials on left	5.1	17.4	26.7	4.2	5.0	4.7	-4.6	-5.2	4.5	-4.0	-3.7	2.1	2.3
Reaction time mean	0.9	2.1	4.2	-1.6	-2.0	-1.7	1.4	1.4	-1.5	1.3	1.4	-0.8	-0.6
Reaction time mean AUC	0.4	1.0	2.2	-1.2	-1.5	-1.2	1.0	1.1	-1.0	0.9	0.9	-0.4	-0.2
Median of all reaction times	1.1	1.8	3.8	-1.5	-1.9	-1.7	1.2	1.4	-1.4	1.2	1.3	-0.7	-0.5
Reaction time omissions	0.3	0.6	1.1	-0.8	-1.0	-0.7	0.4	0.2	-0.7	0.6	0.9	-1.1	-0.7
Reaction time false alarm rate	1.1	1.5	2.5	-0.7	-1.5	-1.3	1.2	1.6	-1.4	1.3	1.2	-1.0	-1.0
Reaction time premature initiation rate	0.3	0.4	0.8	0.6	0.1	0.3	-0.8	-0.4	0.7	-0.9	-0.9	0.8	0.8
Reaction time premature initiations	2.2	6.7	9.2	2.6	2.6	2.6	-3.0	-3.0	2.9	-2.8	-2.6	1.7	1.7
Std. dev. reaction times	0.4	1.5	3.0	-1.3	-1.7	-1.3	1.3	1.1	-1.3	1.1	1.2	-0.9	-0.6
Reaction time trials completed	5.1	17.4	26.7	4.2	5.0	4.7	-4.6	-5.2	4.5	-4.0	-3.7	2.1	2.3
Reaction time trials AUC	4.8	16.5	25.8	4.1	4.9	4.6	-4.5	-5.1	4.4	-3.9	-3.6	2.1	2.2
Run reversals in cocaine runway, females	0.1	0.1	0.5	-0.7	0.0	0.0	0.6	0.6	-0.3	0.3	-0.1	0.1	-0.1
Run reversals in cocaine runway, males	0.2	0.2	0.6	0.7	-0.6	-0.7	0.3	-0.0	-0.0	-0.2	0.2	-0.8	-0.6
Latency to leave start box in cocaine runway	0.1	0.1	0.3	-0.5	0.2	0.4	0.1	0.2	-0.2	0.3	0.1	-0.1	-0.2
Latency to leave start box in cocaine runway, F	0.5	0.7	1.5	0.3	1.0	1.2	-1.1	-0.6	0.7	-0.6	-0.8	0.8	0.6
Latency to leave start box in cocaine runway, M	2.9	2.7	3.7	-1.6	-1.5	-1.6	1.9	1.7	-1.7	1.8	1.7	-1.6	-1.4
Std. dev. time between licks in bursts	0.3	0.6	0.9	-0.7	-0.6	-0.8	0.6	0.7	-0.9	0.9	0.9	-0.9	-0.9
Total sessions with >9 infusions	3.6	4.5	5.2	-2.2	-2.0	-2.0	2.3	1.8	-2.1	2.1	2.1	-2.3	-2.2
Short access day 1 total inactive lever presses	0.8	1.6	2.9	-1.7	-1.0	-0.8	1.5	0.7	-1.1	1.4	1.3	-1.4	-1.3
Short access day 10 total inactive lever presses	0.0	0.2	0.5	-0.6	-0.6	-0.7	-0.5	0.2	-0.4	0.3	0.4	-0.2	-0.1
Short access day 1 total infusions	1.5	3.0	5.1	-2.2	-1.6	-1.5	2.0	1.6	-1.7	1.7	1.6	-1.6	-1.7
Short access day 10 total infusions	1.5	2.6	4.5	-1.8	-1.5	-1.5	2.1	1.7	-1.6	1.5	1.4	-1.4	-1.3
Short access total infusions	2.9	4.1	5.6	-2.0	-1.9	-1.8	2.4	2.0	-2.0	2.0	1.9	-2.0	-2.1
Short access day 1 locomotion	0.6	1.0	2.4	-1.6	-1.1	-1.0	1.1	0.8	-1.0	0.9	0.9	-0.9	-0.7
Short access day 10 total locomotion	1.3	5.2	6.6	-2.4	-2.3	-2.3	2.3	1.7	-2.3	2.3	2.5	-2.6	-2.0
Short access total locomotion	5.7	8.5	11.6	-3.4	-3.0	-2.9	2.8	2.6	-3.0	2.9	3.0	-3.0	-2.7
One hour access (0.3 mA shock)	0.2	0.2	0.8	-0.4	-0.8	-0.9	0.3	0.2	-0.4	0.4	0.6	-0.2	-0.2
Compulsive drug intake	3.5	5.1	9.2	2.6	2.5	2.5	-2.6	-3.0	2.5	-1.9	-1.7	1.3	1.2
One hour access (shock baseline)	0.9	2.3	3.6	-1.7	-1.5	-1.7	1.8	1.9	-1.6	1.3	1.2	-1.0	-1.0
Social response proportion	0.9	1.1	3.7	1.9	1.2	1.3	-0.9	-0.7	0.9	-1.0	-1.0	0.3	0.2
Social responses	0.3	0.4	2.3	1.5	0.6	0.8	-0.4	-0.4	0.4	-0.4	-0.4	0.2	0.2
Social time	1.4	2.1	3.4	1.4	0.8	0.8	-1.8	-1.3	1.5	-1.6	-1.5	1.9	1.8
Soleus weight	1.1	3.4	7.4	1.8	2.7	2.7	-1.1	-1.2	1.6	-1.6	-2.1	1.5	1.2
Bone: stiffness	1.4	2.5	5.3	2.3	1.9	1.7	-1.4	-1.0	1.4	-1.6	-1.6	1.3	1.3
Tibialis anterior weight	4.1	14.1	18.5	4.2	4.2	4.3	-3.8	-3.8	3.9	-3.8	-3.9	2.6	2.6
Time to tail flick, vehicle, before self-admin	0.5	0.6	1.4	-0.5	-0.8	-0.6	1.2	0.9	-0.8	0.7	0.6	-0.8	-0.7
Time to tail flick, vehicle, after self-admin	0.2	0.3	1.4	-0.7	-0.7	-0.6	0.4	1.2	-0.7	0.3	0.2	0.1	-0.3
Time to tail flick, test, before self-admin	0.5	0.6	2.0	-1.4	-1.2	-1.0	0.3	0.1	-0.5	0.4	0.7	0.6	0.5
Time to tail flick, test, after self-admin	0.2	0.2	0.5	0.0	-0.7	-0.7	0.5	0.7	-0.4	0.3	0.4	-0.1	-0.2
Delta time to tail flick, vehicle, before/after SA	0.4	0.4	1.1	-1.1	-0.6	-0.7	0.2	0.8	-0.7	0.7	0.7	-0.1	-0.4
Delta time to tail flick, test, before/after SA	0.2	0.3	0.8	0.8	0.2	-0.1	0.2	0.6	-0.2	0.2	0.1	-0.9	-0.9
Tibia length	3.3	9.2	13.6	3.2	3.2	3.3	-3.4	-3.7	3.4	-3.1	-2.9	1.5	1.9
Ambulatory time before self-admin	0.3	0.8	1.4	-1.2	-1.1	-1.1	1.1	0.8	-0.9	0.9	0.9	-0.3	-0.2
Ambulatory time after self-admin	0.9	1.4	2.7	-1.7	-1.4	-1.4	1.5	0.8	-1.1	1.1	1.1	-0.6	-0.4
Bone: tissue strength	0.2	0.2	1.3	1.1	0.2	0.0	-0.1	-0.3	0.3	-0.4	-0.3	-0.2	-0.2
Total heroin consumption	0.5	0.6	2.1	0.2	0.4	0.5	-0.4	-0.8	0.7	-0.8	-0.8	1.0	1.5
Bone: trabecular number	4.8	9.1	10.7	2.7	3.0	3.0	-2.8	-2.6	3.0	-3.2	-3.3	3.3	3.3
Bone: trabecular spacing	0.7	1.1	1.7	-0.9	-1.2	-1.1	0.8	0.7	-1.0	1.0	1.2	-1.3	-1.2
Bone: trabecular thickness	1.5	2.1	2.8	1.6	1.4	1.3	-1.4	-1.1	1.4	-1.5	-1.6	1.7	1.6
Bone: trabecular tissue density	0.2	0.3	0.9	0.8	0.9	0.7	-0.0	-0.5	0.3	0.1	0.1	-0.6	-0.7
Water consumed over 24 hours	4.0	7.7	9.0	2.6	2.9	2.8	-2.8	-3.0	3.0	-2.8	-2.8	2.6	2.5
Number of responses in last shaping day	11.1	14.3	19.5	-4.4	-3.6	-3.6	4.0	3.7	-3.8	3.9	3.7	-3.5	-3.5