Hub : Genes

LOC120102833

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL intron excision ratio chr5_26462700_26463293 0.1 0.07 1.5e-10 0.1 0.1 0.1 0.1 1.1e-10 5.2e-11 3.2e-11 4.4e-11
2 PL gene expression LOC120102833 0.24 0.1 0.0e+00 0.32 0.32 0.33 0.33 1.3e-35 5.7e-36 5.7e-37 4.6e-37
3 PL intron excision ratio chr5_26463445_26466935 0.05 0.03 1.3e-07 0.07 0.06 0.05 0.06 2.5e-08 3.1e-07 2.8e-06 2.1e-07
4 Brain gene expression LOC120102833 0.12 0.07 2.0e-09 0.08 0.1 0.08 0.09 1.5e-07 1.2e-09 9.4e-08 7.5e-09
5 PL intron excision ratio chr5_26462274_26462629 0.11 0.05 0.0e+00 0.16 0.16 0.16 0.17 3.0e-17 4.0e-17 1.4e-17 1.6e-18
6 OFC gene expression LOC120102833 0.23 0.13 3.0e-05 0.1 0.17 0.17 0.16 1.9e-03 8.3e-05 7.1e-05 1.1e-04
7 BLA gene expression LOC120102833 0.15 0.09 4.3e-08 0.06 0.11 0.1 0.1 2.6e-04 1.5e-06 4.6e-06 3.0e-06
8 IL gene expression LOC120102833 0.27 0.14 1.6e-05 0.18 0.2 0.17 0.17 3.8e-05 1.3e-05 6.9e-05 5.7e-05
9 pVTA gene expression LOC120102833 0.19 0.11 1.1e-03 0.02 0.01 0.04 0.01 4.2e-02 1.6e-01 5.4e-03 1.4e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density5.28.610.32.9-3.0-2.9-2.5-3.13.1-3.2-2.72.8
Area under the delay curve2.93.15.6-2.41.81.71.61.8-1.71.81.4-1.4
BMI with tail1.13.55.02.2-2.0-2.0-2.2-1.91.7-1.8-1.8-0.1
BMI without tail0.51.02.90.9-0.8-0.8-1.5-0.60.6-0.4-0.9-1.7
Body weight1.56.39.63.0-2.8-2.7-3.1-2.42.3-2.3-2.2-1.3
Weight adjusted by age0.10.20.50.20.2-0.00.30.3-0.40.30.5-0.7
Bone surface2.54.45.52.1-2.2-2.2-2.0-2.42.2-2.3-1.91.5
Bone volume3.05.16.22.4-2.4-2.3-2.1-2.52.4-2.5-2.01.8
Breakpoint value in progressive ratio session0.10.10.9-0.10.0-0.1-0.40.1-0.00.2-0.3-0.9
Number of licking bursts0.70.81.40.1-1.0-1.0-0.9-1.10.8-0.9-1.20.8
Context. condit. distance diff. score2.02.46.11.3-1.2-1.3-0.9-1.51.7-1.7-1.52.5
Locomotion velocity, session 10.10.10.50.3-0.1-0.2-0.5-0.10.3-0.2-0.5-0.7
Locomotion distance, session 10.50.60.9-0.51.00.90.90.9-0.70.80.8-0.3
Locomotion velocity, session 20.60.81.1-0.91.01.11.01.0-0.60.80.8-0.0
Locomotion distance, session 21.52.12.8-1.41.61.61.71.6-1.41.51.5-0.5
Locomotion velocity, session 30.70.93.00.4-0.7-0.6-0.5-0.81.0-1.0-1.01.7
Locomotion distance, session 30.30.40.70.7-0.4-0.4-0.4-0.50.8-0.7-0.50.8
Stereotopy head waving bouts, day 30.30.32.1-1.40.30.30.30.3-0.30.4-0.1-0.4
Stereotopy head waving duration, day 30.30.41.8-1.30.40.40.40.4-0.60.60.1-0.4
Locomotion velocity, session 72.93.14.11.5-1.9-2.0-1.2-1.91.8-1.9-1.52.0
Locomotion distance, session 70.60.74.40.8-0.4-0.30.4-0.50.5-0.60.22.1
Stereotopy head waving bouts, day 70.10.10.6-0.80.10.10.20.3-0.20.30.1-0.6
Stereotopy head waving duration, day 70.10.20.5-0.0-0.5-0.5-0.5-0.30.3-0.3-0.3-0.7
Locomotion velocity, session 80.00.00.20.00.10.00.20.10.0-0.1-0.00.5
Locomotion distance, session 80.20.20.7-0.30.60.50.70.4-0.10.20.40.8
Degree of sensitization distance0.10.10.70.1-0.00.00.5-0.0-0.20.00.50.9
Degree of sensitization stereotypy0.20.20.7-0.50.30.20.20.4-0.40.40.3-0.9
Conditioned locomotion0.50.53.2-0.20.30.40.10.5-0.60.70.5-1.8
Cocaine response after cond. corrected0.30.31.4-0.70.60.60.40.20.20.1-0.31.2
Cocaine response after cond. not corrected0.30.42.3-0.20.00.10.0-0.30.6-0.4-0.71.5
Cocaine response before conditioning0.60.81.11.1-1.0-1.1-0.7-1.00.6-0.9-0.50.8
Saline control response1.21.62.61.2-1.4-1.5-1.6-1.11.1-1.1-1.2-0.9
Bone: connectivity density2.43.85.61.6-1.9-1.8-1.5-2.12.2-2.2-1.82.4
Bone: cortical apparent density1.21.53.61.9-1.1-1.1-0.7-1.21.2-1.4-0.71.5
Bone: cortical area1.42.14.82.2-1.5-1.4-1.1-1.51.2-1.4-0.91.3
Bone: cortical porosity0.50.51.20.5-0.9-0.9-1.0-0.6-0.1-0.3-0.5-1.1
Bone: cortical porosity0.80.91.70.9-1.2-1.2-1.3-0.90.2-0.6-0.8-0.8
Bone: cortical thickness0.50.81.70.30.90.91.00.8-1.10.81.30.3
Bone: cortical thickness2.83.25.1-0.92.02.02.21.9-1.91.72.30.4
Bone: cortical tissue density1.31.73.61.9-1.1-1.1-0.7-1.31.3-1.5-0.71.6
Condit. Reinf. active minus inactive responses1.51.72.3-1.11.41.40.91.4-1.41.41.1-1.5
Condit. Reinf. active-inactive response ratio0.60.60.9-0.70.90.90.70.9-0.80.80.7-0.6
Condit. Reinf. active responses2.93.55.1-1.51.91.81.52.0-2.02.01.9-2.3
Condit. Reinf. inactive responses0.40.51.6-0.40.60.50.50.7-0.70.80.7-1.2
Incentive salience index mean2.53.16.7-1.71.61.51.01.8-1.91.91.3-2.6
Condit. Reinf. lever presses1.72.38.1-1.51.31.20.51.4-1.41.60.8-2.8
Condit. Reinf. active minus inactive responses0.70.82.0-0.71.00.90.50.9-0.91.00.6-1.4
Condit. Reinf. active-inactive response ratio0.40.40.6-0.80.80.80.50.7-0.60.70.3-0.4
Condit. Reinf. active responses0.50.74.5-0.20.50.3-0.10.6-0.60.70.3-2.1
Condit. Reinf. inactive responses0.30.32.70.00.20.1-0.20.4-0.20.30.2-1.6
Condit. Reinf. lever presses0.10.10.30.5-0.3-0.4-0.5-0.30.4-0.4-0.5-0.2
Condit. Reinf. lever reinforcers received0.40.63.8-0.30.40.3-0.30.5-0.50.60.0-1.9
Conditioned reinforcement - actives7.47.49.6-3.13.03.12.42.8-2.82.92.3-1.7
Conditioned reinforcement - inactives0.60.72.4-1.50.91.00.80.7-0.50.60.40.4
Conditioned locomotion7.18.511.2-3.33.13.13.23.0-2.92.93.0-0.6
Patch foraging indifference point 0 sec0.71.13.71.9-1.1-1.0-1.0-1.01.0-1.0-0.4-0.3
Patch foraging indifference point AUC0.10.10.4-0.2-0.3-0.2-0.3-0.00.3-0.1-0.0-0.7
Delay disc. indifference point, 0s delay0.40.50.80.2-0.8-0.8-0.6-0.70.9-0.6-0.80.1
Delay disc. indifference point, 16s delay0.10.10.4-0.70.20.1-0.00.1-0.20.2-0.3-0.1
Delay disc. indifference point, 2s delay0.91.02.0-1.40.90.91.01.0-0.91.00.9-1.0
Delay disc. indifference point, 24s delay1.31.21.9-1.31.11.10.71.1-1.21.20.7-1.4
Delay disc. indifference point, 4s delay2.12.23.9-2.01.31.21.21.5-1.31.51.3-1.9
Delay disc. indifference point, 8s delay5.05.26.6-2.42.42.32.12.4-2.62.52.0-1.7
Indifference point function ln k0.30.41.50.5-0.4-0.4-0.3-0.70.5-0.6-0.71.2
Indifference point function log k0.30.41.50.5-0.4-0.4-0.3-0.70.5-0.6-0.71.2
Patch foraging total patch changes 0 sec0.91.54.52.1-1.2-1.2-1.2-1.11.2-1.3-0.6-0.0
Patch foraging total patch changes 12 sec0.70.92.81.7-1.2-1.1-0.8-0.80.8-0.9-0.1-0.2
Patch foraging total patch changes 18 sec0.50.61.41.1-0.8-0.8-0.9-0.50.4-0.5-0.2-1.2
Patch foraging total patch changes 24 sec0.20.20.80.7-0.0-0.10.20.3-0.40.20.7-0.9
Patch foraging total patch changes 6 sec0.30.51.60.5-0.5-0.5-1.0-0.40.5-0.4-0.6-1.3
Patch foraging time to switch 0 sec1.01.52.4-1.01.31.11.11.4-1.51.41.3-1.0
Patch foraging water rate 0 sec1.62.63.31.5-1.7-1.6-1.6-1.71.8-1.7-1.60.7
Patch foraging water rate 12 sec0.71.11.90.5-1.1-1.3-1.2-1.11.0-1.0-1.40.2
Patch foraging water rate 18 sec1.01.31.51.1-1.1-1.2-0.9-1.21.2-1.1-1.11.2
Patch foraging water rate 24 sec0.20.20.50.5-0.6-0.7-0.6-0.50.2-0.3-0.4-0.3
Patch foraging water rate 6 sec1.31.93.01.7-1.4-1.5-1.0-1.51.2-1.4-1.01.4
Seeking ratio, delayed vs. immediate footshock0.80.91.20.9-1.1-1.0-0.9-1.00.7-0.9-0.90.8
Distance traveled before self-admin1.01.11.6-0.81.31.11.21.1-1.10.91.00.6
Distance traveled after self-admin0.10.10.3-0.50.30.20.10.1-0.10.2-0.10.2
Extensor digitorum longus weight0.10.31.61.3-0.4-0.4-0.3-0.50.5-0.5-0.10.4
Bone: elastic displacement1.51.72.3-1.31.51.51.21.4-1.41.41.1-0.4
Bone: elastic work0.81.11.6-0.41.21.21.21.1-1.11.01.30.0
Bone: endosteal estimation4.49.612.22.8-3.4-3.3-3.0-3.33.5-3.4-3.01.7
Bone: endosteal perimeter3.77.79.42.3-3.0-2.9-2.5-3.03.1-3.1-2.72.3
Epididymis fat weight0.20.51.81.3-0.4-0.3-0.9-0.40.7-0.5-0.7-0.5
Delta time in closed arm before/after self-admin0.80.71.51.2-1.0-1.1-0.9-0.90.6-0.8-0.60.3
Delta time in open arm before/after self-admin0.40.41.2-0.0-0.3-0.1-0.9-0.40.7-0.3-1.1-0.6
Diff in mean of infusions in LGA sessions1.31.42.81.2-1.4-1.7-1.3-1.30.8-1.1-1.00.4
Delay discount exponential model param3.73.96.42.5-2.0-1.9-1.8-2.02.0-2.1-1.61.7
Extinction: sum of active levers before priming4.54.57.12.4-2.5-2.7-2.2-2.31.8-2.1-1.80.5
Active lever presses in extinction session 63.63.54.51.9-2.0-2.1-1.6-1.91.9-2.0-1.71.5
Bone: final force1.62.55.92.4-1.7-1.6-1.3-1.71.4-1.6-1.01.2
Bone: final moment1.72.76.72.6-1.8-1.7-1.4-1.71.4-1.7-0.91.1
Food consumed during 24 hour testing period3.54.25.31.7-2.2-2.2-2.0-2.12.3-2.2-2.31.2
Glucose1.62.44.21.7-1.5-1.5-2.0-1.61.4-1.4-1.8-0.2
Heart weight0.10.10.5-0.00.20.20.70.2-0.30.10.60.6
Delay discount hyperbolic model param3.63.86.32.5-2.0-1.9-1.7-2.01.9-2.1-1.61.8
Intermittent access intake day 1-15 change0.20.20.5-0.50.30.40.70.4-0.40.50.6-0.2
Intermittent access intake escalation0.00.00.2-0.2-0.1-0.00.40.0-0.10.10.40.0
Intermittent access intake escalation 20.20.20.9-0.3-0.00.10.6-0.00.2-0.10.20.9
Intermitt. access day 1 inactive lever presses0.00.00.2-0.1-0.1-0.1-0.1-0.0-0.50.20.1-0.0
Intermitt. access day 15 inactive lever presses0.60.61.8-1.40.70.60.70.8-0.90.80.5-0.4
Intermitt. access escalation Index3.02.64.62.1-1.9-2.1-1.4-1.61.6-1.6-1.10.6
Intermittent access day 1 total infusions0.10.10.50.20.20.20.40.2-0.30.20.7-0.0
Intermittent access day 15 total infusions0.10.10.6-0.00.10.10.70.1-0.20.10.80.2
Intermittent access terminal intake (last 3 days)0.30.30.8-0.50.40.50.90.4-0.10.20.70.6
Intermittent access total infusions0.91.01.6-0.81.11.21.21.0-0.90.91.3-0.2
Intermittent access day 1 locomotion0.70.71.0-1.00.90.90.90.9-0.80.81.0-0.1
Intermittent access day 15 total locomotion4.04.35.5-2.32.02.02.12.1-2.32.22.3-1.1
Intermittent access total locomotion2.83.24.4-1.71.92.02.01.8-1.81.82.1-0.5
Intermittent access standard deviation6.67.010.1-2.43.03.22.42.8-2.62.82.4-2.0
Left kidney weight2.16.08.62.7-2.6-2.5-2.9-2.52.5-2.4-2.4-0.5
Right kidney weight3.710.414.43.8-3.7-3.6-3.6-3.43.1-3.3-2.90.2
Cocaine induced anxiety0.91.01.9-0.81.00.91.31.1-1.01.01.4-0.1
Post-drug Anxiety2.52.84.2-2.01.71.52.01.8-1.91.61.7-0.2
Baseline Anxiety0.20.20.9-1.00.50.50.40.3-0.30.3-0.10.5
Tail length0.31.06.60.4-0.5-0.5-1.2-0.30.20.0-0.5-2.6
Length with tail0.51.72.51.6-1.4-1.3-1.6-1.11.1-0.9-0.9-1.6
Length without tail1.12.43.61.9-1.8-1.8-1.4-1.71.6-1.7-1.20.4
Times rat made contact with spout2.22.54.20.5-1.8-1.8-1.8-1.71.8-1.6-2.0-0.1
Lifetime Intake1.41.52.3-1.01.31.31.41.3-1.21.21.5-0.7
Liver weight, left0.81.31.81.1-1.2-1.3-1.3-1.11.2-1.1-1.0-0.7
Liver weight, right0.40.61.30.4-0.7-0.7-1.1-0.60.8-0.7-1.0-0.7
Locomotor activity0.81.22.40.4-1.1-1.2-1.0-1.11.5-1.2-1.30.5
Locomotor testing distance1.93.24.41.1-2.0-2.0-1.6-2.02.1-1.9-1.91.2
Locomotor testing rearing0.10.20.80.3-0.4-0.60.1-0.40.4-0.4-0.10.9
Locomotion in novel chamber2.93.66.01.3-2.0-2.1-1.9-2.02.5-1.8-2.30.7
Locomotion in novel chamber post-restriction0.50.60.8-0.80.60.60.80.8-0.80.80.9-0.6
Fecal boli incidents, locomotor time 10.00.00.1-0.0-0.2-0.4-0.1-0.20.1-0.1-0.1-0.2
Change in fecal boli incidents, locomotor task2.42.23.6-1.31.61.61.31.6-1.91.61.5-0.7
Time >=10cm from walls, locomotor time 10.10.10.3-0.20.60.60.00.4-0.20.4-0.1-0.4
Bouts of movement, locomotor time 11.51.76.3-1.80.90.70.31.1-1.01.20.4-2.5
Total resting periods, locomotor time 11.11.26.5-1.60.50.3-0.00.8-0.70.90.2-2.5
Rest time, locomotor task time 10.80.83.00.4-1.1-1.2-1.0-0.70.1-0.4-0.3-1.7
Distance moved, locomotor task time 10.60.64.70.60.20.30.4-0.20.3-0.3-0.02.2
Vertical activity count, locomotor time 10.30.31.80.20.50.70.60.2-0.10.20.21.3
Time >=10cm from walls, locomotor time 20.80.91.4-0.11.11.21.01.0-0.90.81.2-0.3
Bouts of movement, locomotor time 21.01.03.1-1.30.70.40.41.0-1.11.00.6-1.8
Total resting periods, locomotor time 20.70.73.2-1.10.40.20.00.7-0.80.80.3-1.8
Rest time, locomotor task time 20.20.21.4-0.8-0.1-0.1-0.30.1-0.20.2-0.2-1.2
Distance moved, locomotor task time 20.20.31.10.70.30.30.50.0-0.30.10.51.1
Vertical activity count, locomotor time 20.40.41.80.60.40.30.80.1-0.30.10.71.3
Light reinforcement 11.73.17.62.7-1.9-1.9-1.3-1.81.7-1.8-1.01.1
Light reinforcement 20.91.23.7-0.90.80.70.71.0-1.11.11.1-1.9
Bone: marrow area4.59.812.72.9-3.4-3.4-3.0-3.33.6-3.4-3.01.8
Bone: maximum diameter5.09.212.43.5-3.2-3.1-2.9-3.33.1-3.2-2.82.0
Bone: maximum force1.52.66.22.5-1.6-1.6-1.0-1.61.4-1.6-0.81.9
Bone: maximum moment1.52.66.82.6-1.6-1.6-1.0-1.61.4-1.6-0.71.8
Mean time between licks in bursts1.31.93.3-0.71.21.31.01.3-1.61.51.5-1.8
Mean num. licks in bursts0.10.10.20.4-0.1-0.2-0.2-0.00.4-0.2-0.0-0.5
Cd content in liver1.11.21.71.1-1.1-1.0-1.3-1.11.3-1.1-1.20.3
Co content in liver1.21.53.11.8-1.3-1.3-1.0-1.21.1-1.3-0.70.9
Cu content in liver1.41.73.8-1.91.31.31.31.4-1.31.41.0-0.6
Fe content in liver0.20.21.1-0.1-0.1-0.1-0.3-0.30.5-0.4-0.61.0
K content in liver1.01.05.9-0.40.40.30.20.7-0.90.90.8-2.4
Mg content in liver0.30.31.00.7-0.6-0.6-0.5-0.30.2-0.20.1-1.0
Mn content in liver2.12.43.7-1.31.11.01.41.5-1.91.61.9-1.9
Na content in liver0.40.43.0-0.10.20.1-0.10.4-0.30.40.2-1.7
Rb content in liver0.10.20.30.0-0.5-0.5-0.1-0.40.5-0.5-0.20.4
Se content in liver0.30.41.2-1.10.50.50.40.6-0.50.60.4-0.8
Sr content in liver0.20.20.40.2-0.3-0.3-0.4-0.40.5-0.4-0.60.4
Zn content in liver1.21.42.11.4-1.3-1.3-0.7-1.21.2-1.2-0.61.2
Bone: minimum diameter1.83.34.52.1-1.9-1.9-1.6-2.01.7-1.9-1.51.6
Time in familiar zone, hab. session 12.52.43.41.9-1.5-1.4-1.3-1.51.7-1.6-1.41.5
Time in novel zone, hab. session 10.00.00.2-0.0-0.1-0.1-0.0-0.0-0.20.10.2-0.4
Total zone transitions, hab. session 10.10.10.4-0.00.0-0.10.60.10.2-0.10.40.6
Total locomotion distance, hab. session 11.11.63.8-1.41.21.11.91.0-0.60.71.31.7
Locomotion velocity, hab. session 12.02.85.9-1.91.71.62.41.6-1.21.31.81.2
Time in familiar zone, hab. session 20.20.20.80.9-0.2-0.2-0.4-0.0-0.00.00.1-0.8
Time in novel zone, hab. session 20.50.52.6-0.0-0.4-0.3-0.1-0.60.6-0.6-0.51.6
Total zone transitions, hab. session 20.91.11.7-0.71.10.91.01.1-1.21.11.2-1.3
Total locomotion distance, hab. session 23.24.25.9-2.32.32.12.42.1-2.02.02.1-0.2
Locomotion velocity, hab. session 22.93.95.6-2.32.22.02.42.0-1.91.92.0-0.3
Novel to familiar place preference ratio0.20.20.4-0.30.50.50.50.5-0.60.50.6-0.2
Novelty place preference0.00.00.1-0.00.20.20.20.2-0.30.20.30.1
Time in novel zone, NPP test0.00.00.10.4-0.1-0.1-0.2-0.1-0.0-0.10.0-0.0
Total zone transitions, NPP test0.71.03.2-0.40.90.70.70.9-1.11.11.0-1.8
Total locomotion distance, NPP test2.33.14.3-1.91.91.72.11.9-1.81.81.9-0.7
Locomotion velocity, NPP test3.65.16.6-2.42.42.22.62.4-2.32.32.4-0.9
Intraocular pressure1.21.710.31.2-0.7-0.70.5-0.70.6-1.00.43.2
Delta distance traveled before/after self-admin0.70.71.10.0-1.0-0.9-1.1-0.91.0-0.7-1.1-0.5
Delta ambulatory time before/after self-admin0.30.40.7-0.1-0.6-0.6-0.7-0.50.7-0.3-0.6-0.8
Parametrial fat weight0.10.11.0-0.3-0.1-0.2-0.20.0-0.20.1-0.0-1.0
Pavlov. Cond. lever latency0.40.50.8-0.90.80.70.90.6-0.60.60.50.6
Pavlov. Cond. magazine entry latency0.81.01.60.9-1.0-0.9-1.3-0.91.3-1.1-1.1-0.2
Pavlov. Cond. change in total contacts0.40.40.60.8-0.7-0.7-0.7-0.50.7-0.6-0.4-0.4
Pavlov. Cond. index score0.81.01.71.1-1.1-1.0-1.3-0.91.0-1.0-1.0-0.6
Pavlov. Cond. latency score1.11.42.21.2-1.3-1.2-1.5-1.21.2-1.2-1.2-0.3
Pavlov. Cond. lever contacts0.70.81.41.0-1.0-1.0-1.2-0.90.8-0.8-0.8-0.8
Pavlov. Cond. magazine entry number0.30.30.7-0.10.40.30.80.4-0.70.50.70.7
Pavlov. Cond. intertrial magazine entries1.31.62.5-1.01.21.01.01.3-1.41.51.2-1.6
Pavlov. Cond. lever-magazine prob. diff.0.60.71.30.9-0.9-0.7-1.2-0.70.9-0.8-0.8-0.8
Pavlov. Cond. response bias0.20.31.30.3-0.3-0.2-0.8-0.20.5-0.3-0.5-1.1
Pavlov. Cond. lever latency0.71.01.4-1.11.11.20.81.0-1.01.10.7-0.7
Pavlov. Cond. magazine entry latency0.10.10.30.3-0.1-0.1-0.2-0.20.4-0.4-0.40.6
Pavlov. Cond. change in total contacts0.50.70.80.6-0.8-0.9-0.8-0.90.8-0.8-0.90.8
Pavlov. Cond. index score0.40.50.70.8-0.8-0.8-0.8-0.70.7-0.8-0.70.3
Pavlov. Cond. latency score0.20.20.30.4-0.5-0.6-0.4-0.40.4-0.5-0.40.2
Pavlov. Cond. lever contacts0.81.11.61.2-1.2-1.2-1.0-1.01.0-1.2-0.80.6
Pavlov. Cond. magazine entry number0.50.70.8-0.80.80.80.80.9-0.80.90.8-0.6
Pavlov. Cond. intertrial magazine entries0.71.03.7-0.80.80.80.41.0-0.81.00.6-1.9
Pavlov. Cond. lever-magazine prob. diff.0.50.70.90.8-0.9-0.9-0.9-0.80.8-0.9-0.80.4
Pavlov. Cond. response bias0.50.71.00.9-0.9-0.9-0.8-0.80.9-1.0-0.80.5
Time in closed arm before self-admin0.10.10.3-0.30.20.30.30.10.2-0.1-0.00.6
Time in closed arm after self-admin0.10.11.0-0.10.1-0.00.00.2-0.20.20.3-1.0
Time in open arm before self-admin0.50.51.3-0.20.60.51.00.7-1.10.61.20.2
Time in open arm after self-admin0.10.10.20.0-0.10.0-0.2-0.20.4-0.2-0.40.4
Bone: periosteal estimation4.49.111.83.4-3.3-3.2-2.8-3.23.2-3.2-2.61.9
Bone: periosteal perimeter3.35.46.52.3-2.5-2.5-2.0-2.52.4-2.5-2.12.1
Bone: post-yield work1.62.26.02.5-1.5-1.5-0.9-1.51.1-1.4-0.51.5
Progressive ratio test 1 active lever presses1.51.62.2-1.11.21.11.21.3-1.41.31.5-1.2
Progressive ratio test 1 breakpoint1.01.01.5-1.01.00.91.11.0-1.11.01.2-0.6
Progressive ratio test 1 inactive lever presses2.02.22.8-1.51.51.51.51.6-1.71.61.6-0.9
Progressive ratio test 2 active lever presses2.32.53.3-1.61.61.61.41.6-1.81.61.6-1.2
Progressive ratio test 2 breakpoint1.41.62.2-1.31.31.31.11.3-1.51.31.2-0.9
Progressive ratio test 2 inactive lever presses1.51.72.6-1.31.31.31.41.3-1.61.31.5-0.5
Incentive Sensitization - Responses0.40.41.1-1.10.60.80.20.5-0.60.60.2-0.6
Incentive Sensitization - Breakpoint0.60.61.5-1.20.80.90.30.7-0.80.70.3-0.7
Sum of active levers in priming session hrs 5-60.20.20.4-0.20.50.40.50.4-0.60.40.40.2
Progressive ratio0.60.71.60.3-0.5-0.5-0.8-0.81.3-1.0-1.30.8
Food seeking constrained by brief footshock0.20.30.8-0.40.40.40.80.5-0.40.50.9-0.2
Seeking ratio, punishment vs. effort1.01.22.9-0.70.80.81.41.0-1.51.21.7-0.3
Retroperitoneal fat weight0.30.92.21.5-1.1-1.1-0.8-0.90.8-1.0-0.70.5
Reaction time number correct14.220.530.84.8-5.0-4.8-5.6-4.64.4-4.2-4.6-1.3
Reaction time mean minus median0.60.81.1-0.81.01.10.91.0-1.00.90.80.3
Reaction time mean minus median AUC0.70.91.8-0.51.11.00.91.0-1.31.11.0-0.3
Reaction time num false alarms0.40.61.01.0-0.9-0.9-1.0-0.80.4-0.5-0.6-0.8
Reaction time num false alarms AUC1.31.83.51.9-1.5-1.5-1.6-1.41.0-1.1-1.1-0.7
Reaction time trials correct on left14.220.530.84.8-5.0-4.8-5.6-4.64.4-4.2-4.6-1.3
Reaction time trials on left14.220.330.94.8-5.0-4.8-5.6-4.64.4-4.2-4.6-1.4
Reaction time mean1.41.92.8-1.31.61.71.51.4-1.51.41.30.3
Reaction time mean AUC0.81.01.4-0.81.11.21.21.0-1.11.01.00.6
Median of all reaction times0.91.31.9-1.01.31.41.31.1-1.21.21.10.4
Reaction time omissions0.20.32.1-0.10.20.3-0.40.2-0.40.5-0.1-1.5
Reaction time false alarm rate1.31.82.7-1.01.41.31.61.3-1.61.41.6-0.1
Reaction time premature initiation rate0.30.41.00.3-0.7-0.7-0.2-0.70.5-0.7-0.21.0
Reaction time premature initiations5.27.39.92.6-3.1-3.1-3.1-2.92.7-2.7-2.6-0.0
Std. dev. reaction times1.01.42.1-1.11.41.41.21.2-1.41.21.10.1
Reaction time trials completed14.220.330.94.8-5.0-4.8-5.6-4.64.4-4.2-4.6-1.4
Reaction time trials AUC13.519.429.84.6-4.9-4.7-5.5-4.54.3-4.1-4.5-1.3
Run reversals in cocaine runway, females0.20.20.6-0.60.20.30.70.4-0.00.20.50.4
Run reversals in cocaine runway, males0.20.20.50.7-0.1-0.0-0.10.0-0.70.40.5-0.6
Latency to leave start box in cocaine runway0.20.20.4-0.60.50.40.50.5-0.40.40.4-0.2
Latency to leave start box in cocaine runway, F0.20.20.60.4-0.5-0.4-0.3-0.40.7-0.6-0.40.4
Latency to leave start box in cocaine runway, M2.42.33.1-1.61.61.51.61.6-1.81.61.5-0.5
Std. dev. time between licks in bursts0.81.01.2-0.91.01.00.71.1-1.11.10.9-1.0
Total sessions with >9 infusions2.32.64.9-1.91.51.41.11.6-1.51.61.3-2.2
Short access day 1 total inactive lever presses0.60.72.4-1.00.70.50.30.7-0.70.90.4-1.5
Short access day 10 total inactive lever presses0.10.10.80.4-0.2-0.10.2-0.1-0.3-0.00.40.9
Short access day 1 total infusions1.92.13.2-1.81.51.31.21.4-1.21.41.2-1.7
Short access day 10 total infusions2.32.53.0-1.61.71.61.61.6-1.61.61.7-1.1
Short access total infusions1.51.72.4-1.11.31.21.21.3-1.21.31.4-1.6
Short access day 1 locomotion0.20.20.5-0.70.40.50.20.4-0.30.40.3-0.7
Short access day 10 total locomotion3.03.44.2-1.82.02.01.41.9-2.02.01.6-1.7
Short access total locomotion2.12.22.7-1.61.51.61.21.5-1.51.61.4-1.4
One hour access (0.3 mA shock)0.10.10.5-0.00.20.30.0-0.0-0.00.0-0.20.7
Compulsive drug intake5.25.29.21.9-2.4-2.5-3.0-2.32.1-2.1-2.8-0.4
One hour access (shock baseline)2.22.64.3-1.71.81.82.11.6-1.41.51.70.3
Social response proportion0.91.02.91.7-1.2-1.2-0.9-0.90.6-0.9-0.30.1
Social responses0.10.21.01.0-0.3-0.2-0.4-0.20.2-0.4-0.20.0
Social time1.72.23.81.5-1.4-1.4-1.1-1.51.5-1.5-1.41.9
Soleus weight0.61.73.41.9-1.3-1.4-0.8-1.21.4-1.5-0.61.1
Bone: stiffness1.52.45.82.4-1.7-1.7-1.2-1.71.4-1.6-0.81.2
Tibialis anterior weight3.612.516.94.1-4.0-4.0-3.7-3.73.5-3.7-3.01.1
Time to tail flick, vehicle, before self-admin0.40.40.7-0.80.50.40.60.6-0.80.60.7-0.2
Time to tail flick, vehicle, after self-admin0.30.30.7-0.50.50.60.90.5-0.10.20.70.6
Time to tail flick, test, before self-admin0.30.31.2-1.10.50.6-0.00.30.20.3-0.5-0.4
Time to tail flick, test, after self-admin0.10.10.3-0.40.30.40.50.20.30.10.10.5
Delta time to tail flick, vehicle, before/after SA0.70.71.4-1.11.11.20.90.8-0.20.60.40.1
Delta time to tail flick, test, before/after SA0.10.10.50.20.10.10.60.3-0.20.20.7-0.1
Tibia length3.610.114.13.0-3.7-3.7-3.8-3.52.9-3.1-3.1-0.6
Ambulatory time before self-admin1.51.62.3-1.31.51.41.31.3-1.41.31.0-0.1
Ambulatory time after self-admin0.50.60.8-0.80.90.80.70.7-0.80.80.7-0.3
Bone: tissue strength0.30.31.41.2-0.6-0.7-0.6-0.50.1-0.4-0.1-0.3
Total heroin consumption0.00.00.1-0.10.00.0-0.0-0.0-0.1-0.0-0.10.4
Bone: trabecular number4.36.88.32.7-2.6-2.5-2.2-2.82.7-2.9-2.22.7
Bone: trabecular spacing0.81.02.3-1.20.80.70.61.0-1.01.10.7-1.5
Bone: trabecular thickness1.51.82.71.5-1.3-1.2-1.0-1.41.4-1.4-1.01.6
Bone: trabecular tissue density0.40.52.21.0-0.5-0.6-0.8-0.40.3-0.2-0.3-1.5
Water consumed over 24 hours8.810.612.72.7-3.6-3.5-3.4-3.63.5-3.4-3.61.3
Number of responses in last shaping day11.111.516.4-4.03.53.33.23.6-3.33.53.1-2.9