LOC120101609

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression LOC120101609 0.42 0.19 0.0e+00 0.38 0.39 0.39 0.39 3.0e-21 6.1e-22 4.2e-22 4.2e-22
2 IL gene expression LOC120101609 0.44 0.19 1.2e-11 0.4 0.41 0.42 0.42 1.1e-10 4.7e-11 3.5e-11 3.8e-11
3 Liver intron excision ratio chr3_110329468_110331649 0.06 0.06 5.6e-06 0.05 0.04 0.03 0.03 7.2e-06 3.2e-05 5.9e-04 1.9e-04
4 Eye gene expression LOC120101609 0.87 0.16 1.3e-04 0.25 0.23 0.22 0.23 1.0e-04 1.6e-04 2.8e-04 1.8e-04
5 NAcc gene expression LOC120101609 0.19 0.1 0.0e+00 0.3 0.3 0.3 0.3 1.2e-45 1.5e-46 1.1e-45 6.4e-46
6 LHb gene expression LOC120101609 0.61 0.16 0.0e+00 0.41 0.47 0.42 0.47 8.0e-11 7.7e-13 2.6e-11 1.4e-12
7 OFC gene expression LOC120101609 0.46 0.18 3.3e-11 0.36 0.34 0.33 0.36 1.6e-09 7.3e-09 1.5e-08 2.4e-09
8 Liver intron excision ratio chr3_110349132_110350736 0.02 0.02 8.1e-03 0 0.01 0.01 0.01 1.4e-01 2.9e-02 4.2e-02 6.1e-02
9 pVTA gene expression LOC120101609 0.75 0.17 0.0e+00 0.6 0.64 0.63 0.64 1.5e-59 2.0e-66 5.1e-65 1.3e-65
10 Adipose gene expression LOC120101609 0.04 0.04 9.9e-05 0.03 0.03 0.01 0.02 7.7e-04 6.4e-04 1.3e-02 2.7e-03
11 Liver gene expression LOC120101609 0.08 0.08 1.5e-07 0.05 0.06 0.05 0.05 1.4e-06 9.9e-07 3.2e-06 1.4e-06
12 Brain isoform ratio XR_005502304.2 0.05 0.06 1.5e-04 0.04 0.03 0.03 0.04 5.9e-05 5.3e-04 3.7e-04 8.9e-05
13 Brain isoform ratio XR_010064862.1 0.06 0.06 7.7e-05 0.05 0.03 0.04 0.05 3.0e-05 3.6e-04 9.3e-05 3.4e-05
14 PL gene expression LOC120101609 0.35 0.13 0.0e+00 0.43 0.45 0.44 0.45 6.5e-51 9.4e-55 2.2e-53 7.7e-54
15 Brain gene expression LOC120101609 0.56 0.14 0.0e+00 0.51 0.5 0.52 0.49 5.3e-55 3.4e-53 1.3e-55 2.7e-51
16 IC gene expression LOC120101609 0.46 0.19 1.8e-15 0.3 0.34 0.34 0.31 2.7e-13 5.1e-15 5.8e-15 1.7e-13
17 RMTg gene expression LOC120101609 0.18 0.12 4.6e-05 0.11 0.14 0.18 0.17 9.4e-04 1.4e-04 1.2e-05 2.6e-05
18 NAcc isoform ratio XR_010064862.1 0.01 0.01 5.1e-03 0.01 0.01 0.02 0.01 3.8e-03 1.8e-03 1.1e-03 1.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.71.31.7-1.1-1.1-1.1-1.1-1.2-1.1-1.31.1-1.11.1-1.11.3-1.3-1.2-1.2-1.1-1.10.0
Area under the delay curve0.10.10.20.40.20.40.40.20.20.4-0.20.1-0.20.2-0.10.10.10.10.00.30.0
BMI with tail0.10.40.60.50.60.10.10.60.60.7-0.60.7-0.60.6-0.60.60.70.70.80.70.0
BMI without tail0.00.10.3-0.1-0.3-0.6-0.5-0.2-0.2-0.20.3-0.20.3-0.3-0.00.0-0.2-0.3-0.2-0.50.0
Body weight0.20.91.7-0.9-0.9-1.3-1.2-0.9-0.9-0.91.0-0.80.9-1.00.8-0.8-0.8-0.9-0.8-1.20.0
Weight adjusted by age2.23.34.11.91.81.81.91.81.82.0-1.91.8-1.91.9-2.02.01.81.81.82.00.0
Bone surface0.71.31.9-1.1-1.1-1.1-1.1-1.1-1.1-1.41.1-1.11.1-1.11.3-1.3-1.1-1.1-1.1-1.20.0
Bone volume1.62.93.8-1.8-1.7-1.8-1.8-1.7-1.7-1.91.7-1.71.7-1.71.9-1.9-1.7-1.7-1.6-1.60.0
Breakpoint value in progressive ratio session1.51.82.21.41.31.31.31.51.41.4-1.41.4-1.41.4-1.51.51.51.41.41.20.0
Number of licking bursts0.20.30.5-0.5-0.7-0.4-0.4-0.6-0.6-0.50.6-0.70.6-0.60.5-0.5-0.7-0.7-0.7-0.50.0
Context. condit. distance diff. score3.13.74.4-1.9-1.9-1.7-1.8-2.0-2.0-2.02.0-2.02.0-2.02.1-2.1-2.1-2.1-2.1-2.00.0
Locomotion velocity, session 10.10.10.10.30.40.20.30.30.20.3-0.30.3-0.30.3-0.10.10.30.30.30.20.0
Locomotion distance, session 10.00.00.0-0.00.1-0.2-0.0-0.0-0.0-0.10.0-0.00.00.00.2-0.2-0.0-0.0-0.00.00.0
Locomotion velocity, session 20.00.00.10.30.10.30.30.10.10.2-0.10.0-0.10.00.0-0.0-0.0-0.0-0.10.00.0
Locomotion distance, session 20.20.30.5-0.7-0.5-0.7-0.7-0.6-0.6-0.60.6-0.60.5-0.50.7-0.7-0.5-0.5-0.5-0.50.0
Locomotion velocity, session 30.10.10.2-0.3-0.2-0.3-0.2-0.3-0.3-0.30.2-0.30.2-0.20.5-0.5-0.2-0.2-0.2-0.10.0
Locomotion distance, session 30.20.20.3-0.5-0.3-0.5-0.4-0.4-0.4-0.40.4-0.40.4-0.40.5-0.5-0.4-0.3-0.4-0.30.0
Stereotopy head waving bouts, day 30.00.00.1-0.00.3-0.00.00.20.20.0-0.20.2-0.20.2-0.00.00.30.30.40.20.0
Stereotopy head waving duration, day 30.30.30.5-0.6-0.6-0.5-0.5-0.6-0.6-0.60.6-0.60.6-0.60.7-0.7-0.6-0.6-0.6-0.70.0
Locomotion velocity, session 70.00.00.1-0.30.0-0.2-0.2-0.1-0.1-0.10.1-0.10.1-0.10.1-0.1-0.1-0.10.0-0.10.0
Locomotion distance, session 70.30.40.60.50.80.50.40.70.60.6-0.60.7-0.60.6-0.80.80.70.70.80.70.0
Stereotopy head waving bouts, day 70.00.00.2-0.0-0.20.10.1-0.1-0.1-0.30.1-0.10.1-0.10.4-0.4-0.1-0.1-0.2-0.30.0
Stereotopy head waving duration, day 70.00.00.20.0-0.20.00.1-0.1-0.1-0.20.1-0.10.1-0.10.4-0.4-0.1-0.1-0.2-0.40.0
Locomotion velocity, session 80.40.50.8-0.9-0.6-0.8-0.9-0.7-0.8-0.80.8-0.70.7-0.70.8-0.8-0.7-0.7-0.6-0.80.0
Locomotion distance, session 83.04.45.0-2.2-2.0-2.1-2.2-2.2-2.2-2.22.2-2.12.2-2.12.2-2.2-2.1-2.2-2.1-2.20.0
Degree of sensitization distance0.30.30.70.60.60.60.50.60.50.7-0.50.5-0.50.5-0.80.80.50.40.50.50.0
Degree of sensitization stereotypy0.00.00.10.1-0.10.10.1-0.0-0.0-0.20.0-0.10.0-0.00.4-0.4-0.1-0.1-0.1-0.20.0
Conditioned locomotion3.54.04.62.22.12.12.12.12.12.1-2.12.0-2.12.1-2.02.02.02.02.02.00.0
Cocaine response after cond. corrected2.53.13.71.61.91.61.61.81.81.6-1.81.8-1.81.8-1.91.91.91.81.91.90.0
Cocaine response after cond. not corrected0.60.70.90.80.90.90.90.90.90.8-0.90.9-0.90.9-1.01.00.90.80.90.80.0
Cocaine response before conditioning5.46.48.4-2.2-2.7-2.2-2.1-2.7-2.6-2.32.6-2.72.6-2.72.6-2.6-2.8-2.8-2.9-2.80.0
Saline control response0.71.01.3-0.8-1.1-0.8-0.8-1.0-1.0-0.91.0-1.01.0-1.01.0-1.0-1.1-1.1-1.2-1.10.0
Bone: connectivity density0.60.91.4-0.9-1.0-0.8-0.8-1.0-1.0-1.10.9-1.01.0-0.91.2-1.2-1.0-1.1-1.0-1.00.0
Bone: cortical apparent density0.00.00.1-0.2-0.0-0.2-0.20.10.1-0.3-0.10.2-0.10.10.3-0.30.20.20.3-0.20.0
Bone: cortical area0.20.30.5-0.5-0.7-0.5-0.5-0.5-0.5-0.50.6-0.50.6-0.60.4-0.4-0.5-0.5-0.5-0.70.0
Bone: cortical porosity0.10.10.30.40.30.40.40.30.30.3-0.30.3-0.30.3-0.50.50.30.40.30.50.0
Bone: cortical porosity0.20.20.40.60.40.60.60.40.40.5-0.40.4-0.40.4-0.60.60.40.40.30.50.0
Bone: cortical thickness0.00.00.00.0-0.2-0.0-0.00.00.00.00.00.10.0-0.1-0.00.00.0-0.00.0-0.20.0
Bone: cortical thickness3.44.04.92.21.92.12.12.02.12.2-2.02.0-2.02.0-2.12.12.02.01.92.00.0
Bone: cortical tissue density0.00.00.1-0.2-0.0-0.2-0.20.10.1-0.3-0.00.1-0.10.10.3-0.30.20.20.3-0.20.0
Condit. Reinf. active minus inactive responses1.51.72.4-1.1-1.4-1.0-1.1-1.4-1.4-1.21.4-1.51.4-1.41.4-1.4-1.5-1.4-1.5-1.20.0
Condit. Reinf. active-inactive response ratio3.03.24.1-1.6-1.9-1.6-1.7-1.9-1.9-1.71.8-1.91.9-1.91.9-1.9-2.0-1.9-2.0-1.90.0
Condit. Reinf. active responses0.50.71.0-0.7-0.8-0.5-0.6-0.9-0.9-0.80.8-0.90.9-0.80.9-0.9-0.9-0.9-1.0-0.70.0
Condit. Reinf. inactive responses0.40.50.70.60.70.70.70.80.70.5-0.70.7-0.70.7-0.70.70.80.70.80.70.0
Incentive salience index mean1.31.72.3-1.1-1.4-1.0-1.1-1.4-1.4-1.21.3-1.41.4-1.41.3-1.3-1.4-1.4-1.5-1.30.0
Condit. Reinf. lever presses0.71.01.4-0.8-1.1-0.8-0.9-1.1-1.1-0.91.1-1.11.1-1.11.0-1.0-1.1-1.1-1.2-1.10.0
Condit. Reinf. active minus inactive responses0.91.22.0-0.9-1.2-0.8-0.8-1.2-1.2-0.91.2-1.21.2-1.21.1-1.1-1.3-1.3-1.4-1.20.0
Condit. Reinf. active-inactive response ratio3.03.55.1-1.5-2.0-1.5-1.5-2.0-1.9-1.72.0-2.02.0-2.01.9-1.9-2.1-2.2-2.3-2.10.0
Condit. Reinf. active responses0.60.81.1-0.8-0.9-0.7-0.7-1.0-0.9-0.80.9-1.00.9-0.90.9-0.9-1.0-1.1-1.1-0.90.0
Condit. Reinf. inactive responses0.00.00.10.00.20.10.10.20.20.1-0.20.2-0.30.3-0.20.20.30.30.30.40.0
Condit. Reinf. lever presses0.60.91.4-0.7-1.0-0.8-0.7-1.0-1.0-0.71.0-1.11.0-1.00.9-0.9-1.1-1.1-1.2-0.90.0
Condit. Reinf. lever reinforcers received0.60.81.1-0.8-0.9-0.8-0.7-1.0-0.9-0.80.9-1.00.9-0.90.9-0.9-1.0-1.0-1.0-0.90.0
Conditioned reinforcement - actives2.74.66.0-2.2-2.5-2.2-2.2-2.1-2.2-2.12.2-2.22.2-2.32.1-2.1-2.1-2.3-2.1-2.40.0
Conditioned reinforcement - inactives5.88.59.7-3.1-3.1-3.0-3.0-3.0-3.0-3.13.0-3.03.0-3.02.9-2.9-3.0-3.0-3.0-2.90.0
Conditioned locomotion1.31.63.1-1.6-1.4-1.7-1.8-1.3-1.3-1.51.3-1.21.3-1.21.1-1.1-1.2-1.2-1.0-1.10.0
Patch foraging indifference point 0 sec0.10.30.70.50.50.50.60.40.50.5-0.50.4-0.60.6-0.60.60.50.60.50.80.0
Patch foraging indifference point AUC1.11.62.01.11.21.21.21.41.31.1-1.31.4-1.31.3-1.41.41.41.21.41.10.0
Delay disc. indifference point, 0s delay0.00.00.10.1-0.20.10.1-0.0-0.0-0.10.1-0.10.1-0.10.3-0.3-0.1-0.1-0.1-0.20.0
Delay disc. indifference point, 16s delay1.61.82.31.51.41.51.51.41.41.5-1.41.3-1.31.3-1.41.41.31.31.21.30.0
Delay disc. indifference point, 2s delay0.20.30.80.90.30.80.80.50.50.8-0.50.4-0.50.5-0.20.20.40.40.20.40.0
Delay disc. indifference point, 24s delay0.20.20.30.50.40.50.50.40.40.6-0.40.3-0.40.4-0.50.50.30.30.30.50.0
Delay disc. indifference point, 4s delay0.20.20.40.70.40.70.70.40.40.6-0.40.4-0.40.4-0.30.30.40.40.30.50.0
Delay disc. indifference point, 8s delay0.30.40.6-0.5-0.7-0.4-0.4-0.7-0.6-0.50.6-0.70.6-0.60.6-0.6-0.7-0.7-0.8-0.40.0
Indifference point function ln k0.91.52.0-1.1-1.1-1.3-1.3-1.3-1.3-1.11.2-1.31.2-1.21.4-1.4-1.3-1.3-1.3-1.30.0
Indifference point function log k0.91.52.0-1.1-1.1-1.3-1.3-1.3-1.3-1.11.2-1.31.2-1.21.4-1.4-1.3-1.3-1.3-1.30.0
Patch foraging total patch changes 0 sec0.10.10.50.40.40.30.40.30.30.3-0.40.3-0.40.4-0.40.40.30.40.40.70.0
Patch foraging total patch changes 12 sec0.00.00.0-0.2-0.1-0.1-0.1-0.1-0.1-0.20.1-0.00.1-0.1-0.20.2-0.1-0.10.00.10.0
Patch foraging total patch changes 18 sec0.40.71.10.70.80.91.10.80.90.6-0.80.8-0.80.8-1.01.00.80.70.80.90.0
Patch foraging total patch changes 24 sec0.91.52.01.21.21.21.31.21.21.3-1.31.2-1.31.3-1.41.41.21.21.31.40.0
Patch foraging total patch changes 6 sec0.30.50.60.70.70.70.70.70.70.6-0.70.7-0.80.8-0.60.60.70.70.80.80.0
Patch foraging time to switch 0 sec0.00.00.00.2-0.10.20.10.10.10.2-0.10.1-0.10.1-0.10.10.10.10.10.10.0
Patch foraging water rate 0 sec0.00.00.0-0.10.0-0.2-0.0-0.1-0.1-0.10.1-0.10.1-0.00.0-0.0-0.1-0.1-0.10.10.0
Patch foraging water rate 12 sec0.10.20.60.60.50.60.80.50.50.6-0.50.4-0.50.5-0.50.50.40.30.30.30.0
Patch foraging water rate 18 sec0.61.01.1-1.0-0.9-1.1-1.1-1.0-1.0-0.91.0-1.01.0-1.01.0-1.0-1.0-1.0-1.1-1.00.0
Patch foraging water rate 24 sec0.10.10.30.50.20.50.60.20.20.4-0.20.2-0.20.2-0.30.30.1-0.0-0.00.00.0
Patch foraging water rate 6 sec0.00.00.00.00.10.10.10.00.00.1-0.0-0.0-0.00.0-0.10.1-0.0-0.1-0.10.10.0
Seeking ratio, delayed vs. immediate footshock0.10.10.2-0.2-0.4-0.4-0.4-0.4-0.3-0.30.3-0.30.3-0.30.4-0.4-0.4-0.4-0.3-0.40.0
Distance traveled before self-admin0.00.00.2-0.30.1-0.4-0.3-0.0-0.1-0.30.1-0.00.0-0.0-0.10.10.10.10.20.00.0
Distance traveled after self-admin0.00.00.1-0.00.0-0.1-0.1-0.0-0.1-0.10.1-0.10.1-0.20.0-0.0-0.0-0.1-0.1-0.40.0
Extensor digitorum longus weight0.21.01.41.10.91.01.01.01.01.1-1.01.0-1.00.9-1.21.21.00.90.90.90.0
Bone: elastic displacement1.51.72.31.41.31.41.41.31.31.5-1.31.3-1.31.3-1.51.51.31.21.21.20.0
Bone: elastic work1.41.82.71.31.31.31.31.31.31.4-1.31.3-1.31.3-1.61.61.31.31.31.40.0
Bone: endosteal estimation0.10.20.30.50.50.50.50.40.40.3-0.40.4-0.40.4-0.50.50.40.40.40.50.0
Bone: endosteal perimeter0.40.80.9-0.9-0.9-0.8-0.8-0.9-0.9-1.00.9-0.90.9-0.90.9-0.9-0.9-0.9-0.9-0.80.0
Epididymis fat weight1.03.44.7-1.7-1.8-2.1-2.2-1.9-1.9-1.71.9-1.91.9-1.91.8-1.8-1.9-2.0-1.9-2.00.0
Delta time in closed arm before/after self-admin0.30.30.70.30.70.10.20.60.60.2-0.50.7-0.60.6-0.60.60.70.60.80.50.0
Delta time in open arm before/after self-admin0.40.40.7-0.6-0.7-0.4-0.6-0.8-0.7-0.60.6-0.70.6-0.60.8-0.8-0.8-0.6-0.7-0.30.0
Diff in mean of infusions in LGA sessions1.21.52.01.41.21.31.31.21.21.4-1.21.3-1.21.2-1.41.41.21.21.11.20.0
Delay discount exponential model param0.10.10.2-0.5-0.2-0.5-0.5-0.2-0.3-0.50.3-0.20.3-0.30.2-0.2-0.2-0.2-0.1-0.40.0
Extinction: sum of active levers before priming0.30.30.70.10.70.0-0.10.60.50.1-0.50.6-0.50.5-0.60.60.70.70.80.50.0
Active lever presses in extinction session 60.00.00.3-0.3-0.1-0.5-0.5-0.1-0.2-0.20.2-0.10.1-0.1-0.10.1-0.0-0.00.0-0.10.0
Bone: final force0.00.00.1-0.2-0.1-0.2-0.2-0.2-0.2-0.30.2-0.10.2-0.2-0.00.0-0.1-0.1-0.1-0.10.0
Bone: final moment0.00.00.10.00.20.00.00.10.1-0.1-0.10.1-0.10.1-0.30.30.10.10.20.10.0
Food consumed during 24 hour testing period5.88.19.1-2.9-2.9-2.9-2.9-2.9-2.9-2.93.0-2.93.0-3.02.8-2.8-2.9-3.0-3.0-3.00.0
Glucose2.13.34.0-1.8-2.0-1.7-1.8-1.9-1.9-1.81.9-1.91.9-1.91.8-1.8-1.9-1.9-1.9-1.90.0
Heart weight0.61.01.81.40.81.11.11.01.01.2-1.00.9-1.01.0-0.90.90.91.00.81.00.0
Delay discount hyperbolic model param0.10.10.3-0.6-0.3-0.5-0.5-0.3-0.3-0.50.4-0.30.3-0.30.3-0.3-0.2-0.3-0.2-0.50.0
Intermittent access intake day 1-15 change0.40.91.1-1.0-1.0-1.0-0.9-1.0-1.0-0.91.0-1.01.0-0.91.0-1.0-1.0-1.0-1.0-0.70.0
Intermittent access intake escalation0.61.21.5-1.2-1.2-1.1-1.1-1.2-1.2-1.01.1-1.21.1-1.11.2-1.2-1.2-1.2-1.2-0.90.0
Intermittent access intake escalation 22.12.42.7-1.6-1.6-1.5-1.6-1.6-1.6-1.51.6-1.61.6-1.61.7-1.7-1.6-1.6-1.6-1.40.0
Intermitt. access day 1 inactive lever presses0.00.10.2-0.2-0.2-0.3-0.2-0.1-0.2-0.30.2-0.20.2-0.30.3-0.3-0.2-0.2-0.2-0.50.0
Intermitt. access day 15 inactive lever presses0.51.01.9-1.2-0.9-1.4-1.4-1.0-1.0-1.31.0-0.91.0-1.00.9-0.9-0.9-0.9-0.8-0.90.0
Intermitt. access escalation Index0.10.10.30.1-0.60.10.3-0.3-0.2-0.10.2-0.30.3-0.30.2-0.2-0.4-0.4-0.5-0.40.0
Intermittent access day 1 total infusions2.84.65.7-2.4-2.2-2.4-2.3-2.2-2.2-2.22.2-2.12.2-2.22.1-2.1-2.1-2.2-2.0-2.30.0
Intermittent access day 15 total infusions3.95.96.6-2.6-2.5-2.5-2.5-2.5-2.5-2.42.5-2.52.5-2.52.5-2.5-2.5-2.5-2.4-2.40.0
Intermittent access terminal intake (last 3 days)4.05.35.9-2.4-2.4-2.3-2.3-2.4-2.4-2.22.4-2.42.4-2.42.4-2.4-2.4-2.4-2.4-2.30.0
Intermittent access total infusions5.16.06.8-2.5-2.6-2.5-2.4-2.6-2.5-2.32.5-2.62.5-2.52.5-2.5-2.5-2.6-2.5-2.50.0
Intermittent access day 1 locomotion2.02.53.6-1.9-1.7-1.9-1.9-1.6-1.6-1.71.6-1.61.6-1.61.5-1.5-1.5-1.5-1.4-1.50.0
Intermittent access day 15 total locomotion1.01.93.1-1.8-1.2-1.8-1.7-1.4-1.4-1.61.4-1.41.3-1.31.3-1.3-1.3-1.2-1.1-0.90.0
Intermittent access total locomotion2.12.53.7-1.9-1.6-1.9-1.9-1.7-1.6-1.71.6-1.61.6-1.51.5-1.5-1.5-1.5-1.4-1.30.0
Intermittent access standard deviation2.34.87.0-2.5-2.1-2.5-2.6-2.2-2.2-2.32.2-2.22.2-2.22.1-2.1-2.1-2.1-2.0-2.10.0
Left kidney weight0.62.95.7-1.9-1.6-2.3-2.4-1.6-1.7-1.71.8-1.61.7-1.81.5-1.5-1.5-1.5-1.4-1.90.0
Right kidney weight1.14.98.9-2.5-2.1-2.9-3.0-2.2-2.2-2.42.3-2.12.2-2.22.1-2.1-2.0-2.0-1.8-2.30.0
Cocaine induced anxiety0.10.20.30.40.50.40.50.40.40.4-0.40.5-0.40.4-0.50.50.40.40.40.40.0
Post-drug Anxiety1.81.92.61.61.51.61.61.41.41.6-1.41.4-1.41.4-1.31.31.41.31.31.20.0
Baseline Anxiety0.60.71.81.20.81.31.20.80.91.1-0.90.7-0.90.8-0.70.70.70.70.50.70.0
Tail length0.51.93.6-1.2-1.5-1.4-1.4-1.3-1.3-1.41.5-1.41.5-1.51.1-1.1-1.3-1.5-1.4-1.90.0
Length with tail0.83.45.4-1.7-1.9-1.8-1.8-1.8-1.9-1.81.9-1.91.9-2.01.7-1.7-1.9-2.0-2.0-2.30.0
Length without tail0.72.22.9-1.7-1.4-1.6-1.7-1.5-1.6-1.51.5-1.51.5-1.51.6-1.6-1.5-1.5-1.4-1.50.0
Times rat made contact with spout0.20.20.3-0.5-0.5-0.5-0.5-0.5-0.4-0.50.5-0.50.5-0.50.4-0.4-0.4-0.5-0.4-0.40.0
Lifetime Intake4.75.86.5-2.5-2.6-2.4-2.4-2.5-2.5-2.32.5-2.52.5-2.52.5-2.5-2.5-2.5-2.5-2.50.0
Liver weight, left0.91.52.1-1.3-1.3-1.4-1.4-1.3-1.3-1.21.3-1.21.3-1.31.1-1.1-1.2-1.2-1.2-1.30.0
Liver weight, right0.91.52.6-1.4-1.0-1.6-1.6-1.2-1.3-1.21.3-1.21.3-1.31.1-1.1-1.2-1.2-1.1-1.30.0
Locomotor activity0.00.00.10.1-0.40.00.1-0.3-0.2-0.10.2-0.30.2-0.20.3-0.3-0.3-0.2-0.4-0.00.0
Locomotor testing distance1.01.72.5-1.0-1.6-1.1-1.0-1.4-1.4-1.21.4-1.41.4-1.41.4-1.4-1.5-1.5-1.6-1.30.0
Locomotor testing rearing0.10.20.5-0.2-0.6-0.1-0.2-0.5-0.5-0.30.5-0.50.5-0.50.4-0.4-0.6-0.6-0.7-0.50.0
Locomotion in novel chamber1.21.62.1-1.3-1.4-1.2-1.3-1.3-1.3-1.41.3-1.31.3-1.21.3-1.3-1.3-1.2-1.2-1.00.0
Locomotion in novel chamber post-restriction0.60.91.61.21.01.11.20.90.91.2-0.90.9-0.90.9-1.01.00.80.80.70.90.0
Fecal boli incidents, locomotor time 15.47.89.53.02.93.13.13.02.93.1-2.92.9-2.92.8-2.82.82.92.72.72.50.0
Change in fecal boli incidents, locomotor task6.56.48.0-2.8-2.5-2.8-2.8-2.7-2.7-2.82.6-2.72.6-2.52.6-2.6-2.6-2.4-2.4-2.20.0
Time >=10cm from walls, locomotor time 10.10.10.20.40.30.40.40.40.40.5-0.40.4-0.40.3-0.50.50.40.20.30.30.0
Bouts of movement, locomotor time 10.50.61.21.10.51.01.00.80.81.1-0.70.7-0.70.6-0.80.80.70.50.50.50.0
Total resting periods, locomotor time 10.40.51.01.00.60.90.90.70.71.0-0.60.7-0.60.6-0.70.70.60.50.50.40.0
Rest time, locomotor task time 10.40.51.11.01.00.80.80.80.71.0-0.70.7-0.70.6-0.80.80.70.50.60.50.0
Distance moved, locomotor task time 11.32.03.0-1.6-1.7-1.4-1.4-1.5-1.5-1.71.4-1.51.4-1.41.3-1.3-1.4-1.3-1.4-1.20.0
Vertical activity count, locomotor time 10.10.20.6-0.4-0.7-0.3-0.3-0.4-0.4-0.80.4-0.40.4-0.30.4-0.4-0.4-0.3-0.4-0.20.0
Time >=10cm from walls, locomotor time 24.26.27.3-2.4-2.6-2.4-2.4-2.5-2.5-2.62.6-2.52.6-2.62.6-2.6-2.6-2.6-2.6-2.70.0
Bouts of movement, locomotor time 20.20.30.50.40.60.30.30.60.50.5-0.50.6-0.50.5-0.40.40.60.60.70.50.0
Total resting periods, locomotor time 20.10.20.30.40.50.20.20.50.40.3-0.40.5-0.40.4-0.30.30.50.50.50.30.0
Rest time, locomotor task time 21.62.02.51.31.61.41.41.41.41.5-1.41.4-1.41.4-1.51.51.41.41.41.60.0
Distance moved, locomotor task time 24.45.36.5-2.0-2.5-2.2-2.2-2.4-2.4-2.42.4-2.42.4-2.42.2-2.2-2.5-2.4-2.5-2.50.0
Vertical activity count, locomotor time 22.02.83.8-1.5-1.8-1.7-1.7-1.7-1.7-1.91.7-1.71.7-1.71.7-1.7-1.7-1.6-1.7-1.80.0
Light reinforcement 10.10.20.5-0.6-0.3-0.7-0.6-0.4-0.5-0.50.5-0.30.5-0.50.6-0.6-0.4-0.4-0.3-0.70.0
Light reinforcement 20.00.00.2-0.3-0.1-0.4-0.3-0.2-0.2-0.20.2-0.10.2-0.20.2-0.2-0.1-0.1-0.1-0.30.0
Bone: marrow area0.10.20.30.50.60.50.50.50.50.3-0.50.4-0.50.5-0.50.50.40.50.40.50.0
Bone: maximum diameter0.20.40.6-0.6-0.8-0.6-0.6-0.6-0.6-0.70.7-0.60.7-0.70.6-0.6-0.6-0.7-0.7-0.80.0
Bone: maximum force0.10.20.4-0.6-0.4-0.6-0.6-0.5-0.5-0.60.5-0.50.5-0.50.4-0.4-0.5-0.4-0.4-0.40.0
Bone: maximum moment0.00.00.1-0.20.0-0.2-0.2-0.1-0.1-0.30.1-0.10.1-0.1-0.00.0-0.0-0.00.0-0.00.0
Mean time between licks in bursts0.51.21.51.11.11.01.01.11.11.1-1.11.1-1.21.2-1.11.11.11.21.21.20.0
Mean num. licks in bursts0.00.00.0-0.10.2-0.2-0.20.10.1-0.0-0.00.2-0.10.0-0.10.10.20.10.2-0.00.0
Cd content in liver2.93.24.2-1.6-1.9-1.7-1.7-1.8-1.8-1.91.9-1.81.9-1.91.9-1.9-1.9-1.9-1.9-2.00.0
Co content in liver1.11.31.61.21.11.31.31.11.21.2-1.11.1-1.11.1-1.21.21.11.11.11.10.0
Cu content in liver1.01.21.61.31.21.21.21.11.11.3-1.11.1-1.11.1-1.31.31.01.01.01.00.0
Fe content in liver0.30.40.80.90.50.80.80.60.60.7-0.60.6-0.60.6-0.60.60.50.50.40.50.0
K content in liver3.73.64.71.62.11.71.72.01.91.9-2.02.0-2.02.0-1.91.92.12.12.22.00.0
Mg content in liver1.31.31.81.11.21.11.11.21.21.3-1.11.2-1.11.1-1.31.31.11.11.11.10.0
Mn content in liver1.51.62.21.31.31.31.31.31.31.5-1.31.3-1.31.2-1.41.41.31.31.21.20.0
Na content in liver0.10.10.3-0.3-0.3-0.3-0.3-0.2-0.3-0.40.3-0.20.3-0.30.3-0.3-0.3-0.3-0.3-0.50.0
Rb content in liver1.92.22.71.51.71.61.61.61.61.5-1.51.6-1.51.5-1.61.61.51.51.51.30.0
Se content in liver4.65.46.92.62.32.62.62.32.42.6-2.42.3-2.42.4-2.52.52.22.22.12.50.0
Sr content in liver0.10.10.10.20.20.20.20.30.30.1-0.30.3-0.30.3-0.10.10.30.30.30.30.0
Zn content in liver0.30.30.4-0.7-0.6-0.6-0.6-0.6-0.6-0.70.6-0.60.6-0.60.5-0.5-0.6-0.5-0.5-0.50.0
Bone: minimum diameter0.81.41.9-1.2-1.3-1.2-1.2-1.2-1.2-1.21.3-1.21.3-1.31.0-1.0-1.2-1.3-1.3-1.40.0
Time in familiar zone, hab. session 10.60.50.90.70.80.70.60.90.80.5-0.80.9-0.80.8-0.60.60.90.90.90.60.0
Time in novel zone, hab. session 11.01.01.7-0.9-1.0-1.0-0.8-1.2-1.1-0.71.1-1.21.1-1.10.9-0.9-1.2-1.2-1.3-0.90.0
Total zone transitions, hab. session 12.23.03.8-1.8-1.7-1.8-1.8-1.8-1.8-1.91.8-1.81.8-1.71.9-1.9-1.8-1.7-1.7-1.60.0
Total locomotion distance, hab. session 10.91.32.2-1.4-1.1-1.3-1.3-1.2-1.1-1.51.1-1.11.1-1.01.4-1.4-1.0-1.0-0.9-0.80.0
Locomotion velocity, hab. session 10.60.81.5-1.1-0.8-1.1-1.1-0.9-0.9-1.20.8-0.90.8-0.71.1-1.1-0.8-0.7-0.6-0.60.0
Time in familiar zone, hab. session 20.00.00.1-0.4-0.0-0.2-0.3-0.0-0.0-0.20.00.0-0.00.10.2-0.20.10.20.20.10.0
Time in novel zone, hab. session 20.10.10.20.3-0.20.10.2-0.2-0.20.10.2-0.20.2-0.3-0.00.0-0.3-0.4-0.5-0.30.0
Total zone transitions, hab. session 21.51.92.5-1.6-1.4-1.6-1.5-1.4-1.4-1.51.4-1.41.4-1.41.4-1.4-1.3-1.4-1.3-1.40.0
Total locomotion distance, hab. session 20.00.00.1-0.30.0-0.3-0.2-0.0-0.0-0.30.00.0-0.00.00.1-0.10.10.10.20.10.0
Locomotion velocity, hab. session 20.00.00.1-0.30.1-0.3-0.20.00.0-0.2-0.00.1-0.10.1-0.00.00.20.20.30.20.0
Novel to familiar place preference ratio0.80.91.2-1.1-1.0-1.1-1.1-1.0-1.0-1.01.0-1.01.0-0.90.9-0.9-0.9-0.9-0.9-0.70.0
Novelty place preference0.80.81.1-1.0-1.0-1.0-1.0-1.0-1.0-1.00.9-0.90.9-0.90.9-0.9-0.9-0.8-0.9-0.70.0
Time in novel zone, NPP test0.60.60.8-0.8-0.8-0.8-0.8-0.8-0.8-0.90.8-0.80.8-0.80.8-0.8-0.8-0.7-0.8-0.60.0
Total zone transitions, NPP test0.50.71.11.00.81.01.00.80.80.8-0.90.7-0.80.9-0.70.70.80.80.70.90.0
Total locomotion distance, NPP test0.40.50.80.70.80.70.70.70.70.7-0.80.7-0.80.8-0.60.60.80.80.80.90.0
Locomotion velocity, NPP test0.30.40.70.50.80.60.60.60.70.7-0.70.6-0.70.7-0.60.60.70.70.80.80.0
Intraocular pressure0.00.00.20.20.00.10.10.00.10.1-0.10.0-0.10.1-0.20.20.00.10.00.40.0
Delta distance traveled before/after self-admin0.20.20.50.70.30.70.60.50.50.6-0.40.5-0.40.3-0.40.40.40.30.30.10.0
Delta ambulatory time before/after self-admin0.00.00.10.30.00.30.20.10.10.3-0.00.1-0.0-0.0-0.00.00.0-0.0-0.1-0.30.0
Parametrial fat weight0.10.20.4-0.6-0.5-0.6-0.5-0.4-0.4-0.50.4-0.40.4-0.40.3-0.3-0.4-0.4-0.3-0.20.0
Pavlov. Cond. lever latency0.50.70.90.80.80.80.80.80.90.8-0.90.8-0.90.9-0.80.80.90.90.91.00.0
Pavlov. Cond. magazine entry latency0.70.91.4-1.0-0.9-1.1-1.2-0.9-1.0-1.11.0-0.91.0-1.01.0-1.0-0.9-0.9-0.8-1.20.0
Pavlov. Cond. change in total contacts0.10.20.20.40.50.20.20.40.40.4-0.40.5-0.40.4-0.40.40.50.50.50.40.0
Pavlov. Cond. index score0.30.40.7-0.7-0.6-0.8-0.9-0.6-0.6-0.70.7-0.50.7-0.70.6-0.6-0.5-0.5-0.5-0.70.0
Pavlov. Cond. latency score0.40.40.8-0.8-0.6-0.8-0.9-0.6-0.7-0.70.7-0.60.7-0.70.6-0.6-0.6-0.6-0.5-0.80.0
Pavlov. Cond. lever contacts0.50.60.9-0.7-0.8-0.7-0.8-0.8-0.8-0.80.8-0.80.9-0.90.8-0.8-0.8-0.8-0.9-1.00.0
Pavlov. Cond. magazine entry number0.91.11.61.11.01.21.31.01.11.2-1.10.9-1.11.1-1.11.11.01.00.91.30.0
Pavlov. Cond. intertrial magazine entries0.00.00.10.20.10.30.3-0.00.10.2-0.1-0.0-0.10.1-0.20.2-0.1-0.0-0.10.30.0
Pavlov. Cond. lever-magazine prob. diff.0.30.40.7-0.7-0.6-0.7-0.8-0.6-0.6-0.70.6-0.50.6-0.70.6-0.6-0.5-0.5-0.5-0.70.0
Pavlov. Cond. response bias0.91.11.6-1.0-1.0-1.1-1.2-1.0-1.1-1.21.1-1.01.1-1.11.1-1.1-1.0-1.0-1.0-1.30.0
Pavlov. Cond. lever latency1.62.23.11.31.61.31.21.61.61.2-1.51.6-1.51.5-1.61.61.71.71.81.40.0
Pavlov. Cond. magazine entry latency0.70.81.0-0.9-1.0-1.0-0.9-1.0-1.0-0.80.9-1.00.9-0.90.9-0.9-1.0-0.9-0.9-0.70.0
Pavlov. Cond. change in total contacts0.81.31.9-1.0-1.2-1.1-1.0-1.3-1.2-1.01.2-1.31.2-1.21.2-1.2-1.3-1.3-1.4-1.10.0
Pavlov. Cond. index score1.72.33.0-1.4-1.7-1.4-1.4-1.7-1.6-1.31.6-1.71.6-1.61.5-1.5-1.7-1.7-1.7-1.40.0
Pavlov. Cond. latency score2.12.83.5-1.6-1.8-1.6-1.5-1.8-1.8-1.51.8-1.81.8-1.71.7-1.7-1.9-1.8-1.9-1.60.0
Pavlov. Cond. lever contacts2.33.24.4-1.6-1.9-1.6-1.5-1.9-1.9-1.51.9-2.01.9-1.91.9-1.9-2.0-2.0-2.1-1.70.0
Pavlov. Cond. magazine entry number0.60.81.00.91.01.00.91.01.00.8-0.91.0-0.90.9-0.80.81.00.90.90.70.0
Pavlov. Cond. intertrial magazine entries0.10.20.30.50.40.60.60.50.50.4-0.50.5-0.50.5-0.50.50.50.50.50.40.0
Pavlov. Cond. lever-magazine prob. diff.1.41.92.5-1.2-1.5-1.3-1.2-1.5-1.5-1.11.4-1.51.4-1.41.4-1.4-1.5-1.5-1.6-1.30.0
Pavlov. Cond. response bias1.82.43.3-1.4-1.7-1.4-1.3-1.7-1.7-1.31.6-1.71.6-1.61.6-1.6-1.8-1.7-1.8-1.50.0
Time in closed arm before self-admin2.02.54.3-1.2-1.9-0.9-1.0-1.7-1.6-1.11.7-1.81.7-1.81.6-1.6-1.9-1.8-2.1-1.80.0
Time in closed arm after self-admin0.50.50.9-0.5-0.8-0.6-0.4-0.8-0.8-0.60.8-0.80.8-0.80.6-0.6-0.9-0.8-1.0-0.80.0
Time in open arm before self-admin4.14.55.52.02.31.81.92.22.22.0-2.22.2-2.22.3-2.32.32.32.22.32.30.0
Time in open arm after self-admin1.21.32.51.01.20.90.91.11.11.0-1.21.2-1.21.3-1.01.01.21.31.31.60.0
Bone: periosteal estimation0.00.00.00.10.10.10.10.10.10.0-0.10.1-0.10.0-0.20.20.10.10.10.00.0
Bone: periosteal perimeter1.22.02.3-1.5-1.5-1.5-1.5-1.4-1.4-1.51.5-1.41.5-1.51.4-1.4-1.4-1.4-1.4-1.50.0
Bone: post-yield work0.00.00.1-0.1-0.2-0.1-0.1-0.2-0.2-0.20.2-0.20.2-0.20.2-0.2-0.2-0.2-0.3-0.20.0
Progressive ratio test 1 active lever presses3.23.94.8-2.1-2.1-2.0-1.9-2.0-2.0-1.92.1-2.02.1-2.12.0-2.0-2.0-2.1-2.0-2.20.0
Progressive ratio test 1 breakpoint3.23.94.9-2.0-2.1-2.0-1.9-2.0-2.0-1.92.1-2.02.1-2.12.0-2.0-2.0-2.1-2.0-2.20.0
Progressive ratio test 1 inactive lever presses1.21.72.3-1.5-1.3-1.5-1.5-1.3-1.3-1.41.4-1.21.3-1.41.3-1.3-1.2-1.2-1.2-1.30.0
Progressive ratio test 2 active lever presses6.07.08.7-2.9-2.8-2.8-2.7-2.7-2.7-2.82.8-2.72.7-2.72.6-2.6-2.7-2.7-2.6-2.70.0
Progressive ratio test 2 breakpoint6.37.29.0-3.0-2.9-2.8-2.7-2.8-2.8-2.92.8-2.72.8-2.82.7-2.7-2.7-2.7-2.6-2.70.0
Progressive ratio test 2 inactive lever presses3.04.86.3-2.5-2.3-2.4-2.4-2.2-2.3-2.42.3-2.22.3-2.32.1-2.1-2.1-2.1-2.0-2.10.0
Incentive Sensitization - Responses3.65.16.9-2.6-2.4-2.5-2.4-2.3-2.3-2.62.3-2.32.3-2.32.2-2.2-2.2-2.2-2.1-2.10.0
Incentive Sensitization - Breakpoint3.74.96.6-2.6-2.3-2.5-2.4-2.3-2.3-2.52.3-2.22.3-2.22.1-2.1-2.2-2.2-2.1-2.00.0
Sum of active levers in priming session hrs 5-61.41.32.00.81.30.80.71.21.20.9-1.11.3-1.21.1-1.21.21.31.31.41.10.0
Progressive ratio0.30.50.8-0.9-0.7-0.8-0.8-0.7-0.7-0.80.7-0.70.8-0.80.8-0.8-0.7-0.6-0.6-0.70.0
Food seeking constrained by brief footshock0.70.81.1-1.0-0.9-1.0-0.9-1.0-1.0-1.01.0-1.01.0-1.00.8-0.8-0.9-0.8-0.9-0.80.0
Seeking ratio, punishment vs. effort0.00.10.10.40.20.30.30.20.20.3-0.30.2-0.30.3-0.30.30.20.20.20.40.0
Retroperitoneal fat weight11.047.050.9-7.0-6.9-7.1-7.1-7.1-7.1-7.07.1-7.17.1-7.07.1-7.1-7.1-7.1-7.0-7.00.0
Reaction time number correct0.00.10.20.40.10.40.40.20.20.4-0.10.1-0.10.1-0.30.30.10.0-0.00.10.0
Reaction time mean minus median0.10.20.6-0.8-0.2-0.8-0.8-0.4-0.5-0.50.5-0.40.4-0.40.3-0.3-0.3-0.4-0.2-0.40.0
Reaction time mean minus median AUC0.10.20.6-0.7-0.2-0.8-0.8-0.5-0.5-0.50.5-0.50.5-0.50.4-0.4-0.4-0.4-0.3-0.40.0
Reaction time num false alarms1.52.12.71.51.61.51.41.41.51.5-1.51.4-1.41.4-1.61.61.41.51.41.60.0
Reaction time num false alarms AUC2.03.13.81.81.81.91.81.81.81.9-1.81.7-1.81.8-2.02.01.71.81.71.90.0
Reaction time trials correct on left0.00.10.20.40.10.40.40.20.20.4-0.10.1-0.10.1-0.30.30.10.0-0.00.10.0
Reaction time trials on left0.00.10.30.50.20.50.50.30.30.5-0.20.2-0.20.2-0.40.40.20.10.10.20.0
Reaction time mean0.20.40.6-0.7-0.6-0.7-0.7-0.6-0.6-0.60.6-0.60.6-0.60.5-0.5-0.6-0.6-0.5-0.70.0
Reaction time mean AUC0.40.60.8-0.9-0.8-0.8-0.9-0.8-0.8-0.80.8-0.80.8-0.80.7-0.7-0.8-0.8-0.7-0.90.0
Median of all reaction times0.30.50.7-0.8-0.8-0.7-0.8-0.7-0.7-0.70.7-0.70.7-0.80.6-0.6-0.7-0.7-0.6-0.80.0
Reaction time omissions0.91.31.80.91.30.91.01.21.11.0-1.11.2-1.11.2-1.31.31.21.31.31.30.0
Reaction time false alarm rate2.23.13.91.71.91.71.61.81.81.7-1.81.8-1.81.8-1.91.91.81.91.82.00.0
Reaction time premature initiation rate0.10.20.40.60.20.50.60.50.50.5-0.40.5-0.40.4-0.60.60.50.40.40.30.0
Reaction time premature initiations0.20.30.70.80.30.70.80.60.50.7-0.50.5-0.50.4-0.70.70.50.50.40.30.0
Std. dev. reaction times0.00.10.2-0.4-0.1-0.4-0.4-0.2-0.3-0.30.3-0.20.3-0.30.1-0.1-0.2-0.2-0.1-0.20.0
Reaction time trials completed0.00.10.30.50.20.50.50.30.30.5-0.20.2-0.20.2-0.40.40.20.10.10.20.0
Reaction time trials AUC0.00.00.10.30.00.30.30.10.10.3-0.00.0-0.0-0.0-0.20.2-0.0-0.0-0.10.00.0
Run reversals in cocaine runway, females0.10.10.3-0.5-0.4-0.4-0.5-0.4-0.4-0.40.4-0.30.4-0.40.4-0.4-0.3-0.3-0.3-0.40.0
Run reversals in cocaine runway, males4.34.45.02.12.22.01.92.22.22.0-2.22.2-2.22.2-2.22.22.22.22.22.10.0
Latency to leave start box in cocaine runway0.30.30.60.10.50.30.20.50.50.3-0.50.6-0.50.6-0.70.70.60.70.80.80.0
Latency to leave start box in cocaine runway, F0.10.10.2-0.30.1-0.3-0.40.00.0-0.0-0.10.2-0.10.2-0.40.40.20.30.40.40.0
Latency to leave start box in cocaine runway, M0.40.30.70.60.60.80.80.60.60.3-0.60.6-0.60.6-0.50.50.60.60.60.50.0
Std. dev. time between licks in bursts0.30.40.90.90.60.80.80.60.60.8-0.60.5-0.60.6-0.70.70.50.50.40.60.0
Total sessions with >9 infusions2.12.53.1-1.7-1.8-1.6-1.6-1.6-1.6-1.61.6-1.61.6-1.71.6-1.6-1.6-1.7-1.6-1.70.0
Short access day 1 total inactive lever presses0.91.21.5-1.2-1.2-1.0-1.0-1.1-1.1-1.21.1-1.21.1-1.11.2-1.2-1.1-1.1-1.1-1.10.0
Short access day 10 total inactive lever presses0.00.10.3-0.4-0.2-0.5-0.5-0.3-0.3-0.60.3-0.20.3-0.20.4-0.4-0.2-0.1-0.1-0.10.0
Short access day 1 total infusions3.24.35.5-2.0-2.3-1.8-1.9-2.1-2.1-2.22.2-2.22.2-2.22.1-2.1-2.1-2.2-2.2-2.30.0
Short access day 10 total infusions3.13.94.6-2.1-2.1-2.1-2.1-2.1-2.0-2.02.0-2.02.0-2.02.0-2.0-2.0-2.0-2.0-1.90.0
Short access total infusions3.54.55.4-2.2-2.3-2.1-2.2-2.2-2.2-2.22.2-2.12.2-2.22.1-2.1-2.1-2.2-2.1-2.20.0
Short access day 1 locomotion2.53.23.8-1.9-1.9-1.8-1.9-1.9-1.8-1.91.8-1.91.8-1.81.8-1.8-1.8-1.8-1.8-1.70.0
Short access day 10 total locomotion2.34.36.7-2.5-2.1-2.6-2.6-2.1-2.2-2.42.1-2.02.1-2.02.0-2.0-2.0-1.9-1.8-1.80.0
Short access total locomotion3.23.95.3-2.3-2.1-2.3-2.3-2.0-2.0-2.22.0-2.02.0-1.92.0-2.0-1.9-1.9-1.8-1.70.0
One hour access (0.3 mA shock)4.85.68.1-2.9-2.4-2.8-2.9-2.4-2.4-2.72.4-2.22.4-2.32.3-2.3-2.2-2.2-2.0-2.10.0
Compulsive drug intake3.84.55.91.92.21.91.82.22.21.9-2.22.3-2.22.2-2.32.32.32.32.42.40.0
One hour access (shock baseline)6.510.011.2-3.4-3.3-3.3-3.2-3.3-3.3-3.33.3-3.23.3-3.33.3-3.3-3.2-3.2-3.2-3.20.0
Social response proportion4.24.75.32.22.22.32.32.32.32.2-2.22.2-2.22.2-2.22.22.32.32.32.20.0
Social responses0.00.00.1-0.3-0.2-0.3-0.3-0.2-0.2-0.20.2-0.20.2-0.20.1-0.1-0.1-0.2-0.1-0.10.0
Social time1.92.53.71.91.31.71.81.61.71.7-1.71.6-1.71.6-1.61.61.61.61.51.60.0
Soleus weight1.33.74.61.82.01.81.82.02.01.8-2.02.0-2.02.1-2.02.02.12.12.12.10.0
Bone: stiffness0.71.11.5-1.2-1.0-1.2-1.2-1.0-1.1-1.21.1-1.01.1-1.01.1-1.1-1.0-0.9-0.9-1.00.0
Tibialis anterior weight2.89.411.03.33.03.33.23.23.23.2-3.13.1-3.13.1-3.33.33.13.03.03.00.0
Time to tail flick, vehicle, before self-admin2.32.43.9-2.0-1.5-1.9-1.9-1.6-1.6-1.91.6-1.61.6-1.51.5-1.5-1.5-1.4-1.3-1.30.0
Time to tail flick, vehicle, after self-admin4.05.26.4-2.2-2.5-2.1-2.2-2.4-2.3-2.22.4-2.42.4-2.42.3-2.3-2.4-2.5-2.5-2.40.0
Time to tail flick, test, before self-admin1.92.02.8-1.2-1.4-1.2-1.2-1.5-1.5-1.31.4-1.51.5-1.41.6-1.6-1.6-1.6-1.7-1.50.0
Time to tail flick, test, after self-admin4.64.86.9-2.0-2.3-1.7-1.8-2.4-2.3-2.02.3-2.52.3-2.32.3-2.3-2.5-2.4-2.6-2.20.0
Delta time to tail flick, vehicle, before/after SA0.10.10.40.1-0.50.10.1-0.3-0.30.10.3-0.40.3-0.30.4-0.4-0.5-0.5-0.6-0.50.0
Delta time to tail flick, test, before/after SA0.10.10.2-0.3-0.5-0.0-0.2-0.4-0.3-0.30.3-0.40.3-0.30.3-0.3-0.4-0.4-0.4-0.20.0
Tibia length0.20.61.01.00.80.90.90.90.81.0-0.80.9-0.70.7-0.90.90.80.70.70.40.0
Ambulatory time before self-admin0.00.00.10.10.30.00.10.30.20.1-0.20.2-0.20.2-0.30.30.30.30.30.10.0
Ambulatory time after self-admin0.20.20.7-0.2-0.4-0.3-0.3-0.3-0.4-0.30.5-0.40.5-0.50.4-0.4-0.4-0.5-0.5-0.80.0
Bone: tissue strength0.00.00.1-0.10.3-0.1-0.10.00.0-0.2-0.10.1-0.10.2-0.10.10.10.20.20.30.0
Total heroin consumption1.01.21.70.90.90.91.01.21.10.9-1.11.2-1.11.1-1.31.31.21.21.31.00.0
Bone: trabecular number0.50.91.1-0.8-1.0-0.8-0.8-1.0-0.9-1.00.9-1.00.9-0.91.0-1.0-1.0-1.0-1.0-1.00.0
Bone: trabecular spacing0.10.10.3-0.5-0.4-0.5-0.5-0.4-0.4-0.30.4-0.30.4-0.40.3-0.3-0.3-0.3-0.3-0.40.0
Bone: trabecular thickness0.50.61.1-0.8-0.8-0.8-0.8-0.8-0.8-1.00.8-0.80.8-0.80.8-0.8-0.8-0.8-0.8-0.80.0
Bone: trabecular tissue density0.71.01.80.81.20.80.81.11.10.6-1.11.2-1.11.1-0.80.81.21.31.31.10.0
Water consumed over 24 hours0.40.60.8-0.7-0.9-0.7-0.7-0.8-0.8-0.70.8-0.80.8-0.80.6-0.6-0.8-0.9-0.9-0.80.0
Number of responses in last shaping day3.33.64.6-2.0-2.2-1.7-1.7-1.9-1.9-2.12.0-2.02.0-2.01.9-1.9-1.9-2.0-1.9-2.10.0