Hub : Genes

LOC120099979

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression LOC120099979 0.16 0.09 1.6e-13 0.12 0.16 0.15 0.15 1.6e-09 9.0e-13 8.9e-12 3.1e-12
2 Brain gene expression LOC120099979 0.44 0.11 0.0e+00 0.39 0.37 0.39 0.39 1.8e-38 2.2e-36 9.6e-39 5.3e-38
3 NAcc gene expression LOC120099979 0.11 0.06 5.6e-17 0.12 0.12 0.12 0.12 4.9e-17 1.1e-17 1.1e-17 1.9e-17
4 OFC gene expression LOC120099979 0.32 0.14 1.6e-06 0.25 0.14 0.22 0.06 1.0e-06 2.8e-04 5.8e-06 1.3e-02
5 LHb gene expression LOC120099979 0.22 0.12 1.8e-04 0.2 0.15 0.11 0.06 2.2e-05 2.2e-04 1.3e-03 1.5e-02
6 BLA gene expression LOC120099979 0.22 0.11 9.7e-09 0.16 0.14 0.13 0.14 8.7e-09 1.1e-07 3.4e-07 6.2e-08
7 IC gene expression LOC120099979 0.33 0.19 6.4e-09 0.21 0.18 0.16 0.2 4.8e-09 3.6e-08 2.2e-07 7.3e-09
8 PL gene expression LOC120099979 0.19 0.09 0.0e+00 0.22 0.2 0.21 0.21 3.6e-23 5.3e-22 2.4e-22 1.1e-22
9 IL gene expression LOC120099979 0.36 0.16 2.0e-06 0.23 0.17 0.2 0.08 2.9e-06 5.9e-05 1.3e-05 5.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.61.11.6-0.50.9-1.11.01.11.11.31.11.2
Area under the delay curve0.91.41.7-0.91.3-1.11.21.31.21.11.21.1
BMI with tail0.31.01.40.10.8-1.11.11.11.11.11.11.2
BMI without tail0.10.71.00.20.7-0.61.01.01.00.90.90.9
Body weight0.41.85.42.3-1.51.4-1.1-0.9-0.9-1.2-1.2-1.2
Weight adjusted by age0.92.53.01.6-1.71.5-1.5-1.5-1.5-1.6-1.6-1.6
Bone surface0.30.62.21.5-1.10.6-0.6-0.6-0.5-0.5-0.6-0.5
Bone volume0.00.10.20.4-0.3-0.20.10.20.20.30.20.3
Breakpoint value in progressive ratio session1.32.43.21.8-1.71.4-1.5-1.5-1.4-1.5-1.4-1.6
Number of licking bursts0.10.40.60.6-0.50.4-0.7-0.8-0.7-0.5-0.7-0.6
Context. condit. distance diff. score1.51.82.3-1.51.5-1.31.51.41.51.21.21.2
Locomotion velocity, session 10.10.10.10.2-0.40.3-0.1-0.3-0.3-0.1-0.2-0.1
Locomotion distance, session 10.30.40.7-0.20.6-0.70.80.60.60.80.60.7
Locomotion velocity, session 20.60.81.61.3-1.00.8-0.8-0.8-0.9-0.6-0.8-0.7
Locomotion distance, session 20.10.10.20.20.1-0.20.40.40.30.40.50.4
Locomotion velocity, session 30.50.60.8-0.70.8-0.90.70.90.80.80.80.7
Locomotion distance, session 30.00.00.0-0.10.0-0.10.00.10.10.10.10.1
Stereotopy head waving bouts, day 31.92.32.6-1.41.6-1.51.51.61.51.51.51.5
Stereotopy head waving duration, day 31.82.32.5-1.51.6-1.51.41.61.51.51.51.5
Locomotion velocity, session 71.31.41.9-1.01.2-1.21.41.21.41.21.11.1
Locomotion distance, session 70.40.50.8-0.30.8-0.50.80.90.90.60.60.5
Stereotopy head waving bouts, day 70.30.40.5-0.60.4-0.70.60.60.50.60.60.7
Stereotopy head waving duration, day 70.00.00.10.2-0.1-0.2-0.0-0.0-0.10.20.10.3
Locomotion velocity, session 80.60.71.31.1-0.81.0-0.9-0.8-0.7-0.7-0.8-0.7
Locomotion distance, session 80.60.81.2-0.90.8-0.91.10.91.00.80.80.8
Degree of sensitization distance0.40.50.7-0.40.8-0.60.80.70.80.60.60.6
Degree of sensitization stereotypy0.10.10.30.4-0.60.2-0.2-0.3-0.3-0.3-0.3-0.2
Conditioned locomotion1.11.32.31.5-1.21.4-0.9-0.9-0.9-1.1-1.1-1.2
Cocaine response after cond. corrected0.50.81.1-1.01.0-0.71.01.01.00.70.70.7
Cocaine response after cond. not corrected0.40.50.8-0.90.9-0.70.70.70.70.60.60.5
Cocaine response before conditioning0.60.71.30.7-0.90.6-1.1-1.0-1.1-0.6-0.7-0.7
Saline control response1.21.73.31.8-1.31.3-1.3-1.2-1.2-1.1-1.2-1.2
Bone: connectivity density0.10.20.30.60.2-0.30.40.40.40.50.40.4
Bone: cortical apparent density0.30.50.70.7-0.70.8-0.6-0.9-0.7-0.7-0.8-0.7
Bone: cortical area1.01.62.11.3-1.51.3-1.2-1.3-1.2-1.3-1.2-1.3
Bone: cortical porosity0.20.20.3-0.20.4-0.50.30.30.10.60.50.6
Bone: cortical porosity0.00.00.10.10.1-0.20.00.1-0.10.40.30.4
Bone: cortical thickness5.59.29.83.1-2.93.1-2.9-3.1-2.9-3.1-3.0-3.1
Bone: cortical thickness1.51.92.21.4-1.11.4-1.4-1.5-1.4-1.3-1.4-1.3
Bone: cortical tissue density0.50.71.00.9-0.80.9-0.8-1.0-0.9-0.8-0.9-0.8
Condit. Reinf. active minus inactive responses0.00.00.10.2-0.20.00.2-0.00.0-0.2-0.0-0.1
Condit. Reinf. active-inactive response ratio0.00.00.10.0-0.1-0.00.2-0.10.0-0.1-0.0-0.0
Condit. Reinf. active responses0.00.00.20.1-0.3-0.00.40.10.2-0.20.0-0.1
Condit. Reinf. inactive responses0.10.10.4-0.20.1-0.30.60.60.50.20.40.2
Incentive salience index mean0.00.00.10.2-0.2-0.00.40.10.2-0.10.1-0.0
Condit. Reinf. lever presses0.20.30.60.6-0.70.5-0.1-0.3-0.1-0.7-0.4-0.6
Condit. Reinf. active minus inactive responses0.10.20.5-0.60.4-0.70.30.40.40.30.50.3
Condit. Reinf. active-inactive response ratio0.30.51.0-1.00.5-0.90.60.70.80.50.60.5
Condit. Reinf. active responses0.20.30.6-0.50.6-0.80.30.40.30.60.50.4
Condit. Reinf. inactive responses0.10.20.6-0.00.7-0.60.10.20.10.80.30.5
Condit. Reinf. lever presses0.60.91.31.2-1.00.7-1.0-0.9-0.9-0.9-0.8-0.9
Condit. Reinf. lever reinforcers received0.00.10.2-0.10.3-0.5-0.00.10.10.30.20.1
Conditioned reinforcement - actives0.10.50.90.4-0.90.5-0.8-0.8-0.8-0.7-0.7-0.8
Conditioned reinforcement - inactives0.41.12.3-1.50.6-1.10.91.01.10.91.11.0
Conditioned locomotion2.13.26.5-2.51.6-1.81.61.71.71.71.61.7
Patch foraging indifference point 0 sec0.10.20.4-0.50.6-0.60.40.40.40.20.40.3
Patch foraging indifference point AUC1.23.03.81.9-1.91.7-1.6-1.7-1.7-1.6-1.7-1.6
Delay disc. indifference point, 0s delay2.83.23.8-1.51.9-1.61.81.91.81.81.81.8
Delay disc. indifference point, 16s delay0.91.31.4-1.21.1-1.21.11.21.21.21.11.2
Delay disc. indifference point, 2s delay0.40.50.6-0.70.7-0.80.70.60.50.70.70.7
Delay disc. indifference point, 24s delay0.00.00.1-0.10.30.00.20.20.20.10.10.1
Delay disc. indifference point, 4s delay1.41.41.9-0.91.4-1.11.31.21.21.21.31.2
Delay disc. indifference point, 8s delay0.61.01.5-0.71.2-0.91.01.21.20.91.10.9
Indifference point function ln k1.95.99.3-3.02.6-2.42.22.42.32.12.42.2
Indifference point function log k1.95.99.3-3.02.6-2.42.22.42.32.12.42.2
Patch foraging total patch changes 0 sec0.00.00.1-0.10.2-0.10.00.1-0.0-0.20.0-0.1
Patch foraging total patch changes 12 sec1.62.24.02.0-1.31.4-1.3-1.5-1.3-1.4-1.5-1.4
Patch foraging total patch changes 18 sec0.10.10.30.5-0.40.3-0.4-0.4-0.4-0.3-0.5-0.4
Patch foraging total patch changes 24 sec0.72.53.01.7-1.41.5-1.4-1.5-1.5-1.7-1.7-1.7
Patch foraging total patch changes 6 sec0.20.40.91.0-0.30.6-0.5-0.6-0.5-0.7-0.7-0.7
Patch foraging time to switch 0 sec0.00.10.20.5-0.2-0.20.20.30.30.40.30.4
Patch foraging water rate 0 sec0.10.31.5-1.20.6-0.30.40.40.4-0.10.2-0.1
Patch foraging water rate 12 sec0.62.35.5-2.31.9-1.41.41.21.21.31.41.3
Patch foraging water rate 18 sec0.41.02.1-1.41.4-0.90.90.80.80.80.80.8
Patch foraging water rate 24 sec0.50.72.0-1.41.0-0.60.80.80.90.60.80.6
Patch foraging water rate 6 sec0.30.51.6-1.31.0-0.50.60.60.70.30.50.2
Seeking ratio, delayed vs. immediate footshock0.60.91.1-0.80.9-1.01.10.90.91.01.01.0
Distance traveled before self-admin0.00.00.10.2-0.3-0.0-0.0-0.1-0.1-0.0-0.10.0
Distance traveled after self-admin0.10.10.20.4-0.50.3-0.2-0.2-0.2-0.4-0.4-0.4
Extensor digitorum longus weight4.216.926.55.2-4.34.3-3.7-3.7-3.5-4.1-3.9-4.1
Bone: elastic displacement0.20.30.50.2-0.30.7-0.2-0.5-0.5-0.7-0.6-0.7
Bone: elastic work1.82.33.11.7-1.31.8-1.2-1.4-1.3-1.7-1.5-1.7
Bone: endosteal estimation2.25.46.2-2.22.0-2.32.42.52.52.32.42.3
Bone: endosteal perimeter2.45.96.6-2.52.1-2.62.42.52.52.42.52.3
Epididymis fat weight1.15.79.9-3.12.2-2.42.42.32.22.32.22.3
Delta time in closed arm before/after self-admin0.10.10.20.50.10.40.0-0.1-0.1-0.2-0.2-0.3
Delta time in open arm before/after self-admin0.30.40.80.5-0.90.5-0.7-0.6-0.6-0.5-0.4-0.5
Diff in mean of infusions in LGA sessions0.51.01.21.1-1.01.0-0.9-1.1-1.0-0.9-0.9-1.0
Delay discount exponential model param0.70.91.20.7-1.10.9-1.0-1.0-1.0-0.9-1.0-0.9
Extinction: sum of active levers before priming0.40.61.21.1-0.80.6-0.7-0.8-0.7-0.7-0.6-0.8
Active lever presses in extinction session 63.33.34.21.8-2.11.7-1.9-1.7-1.8-1.8-1.7-1.9
Bone: final force0.91.42.61.6-1.41.2-1.0-1.0-0.8-1.1-1.0-1.2
Bone: final moment0.81.22.31.5-1.31.2-1.0-0.9-0.8-1.1-0.9-1.1
Food consumed during 24 hour testing period0.40.81.20.6-1.00.8-1.1-1.0-0.9-0.9-0.9-0.9
Glucose5.18.18.6-2.82.7-2.92.82.92.82.92.92.9
Heart weight4.67.49.1-2.33.0-2.62.82.72.82.82.72.7
Delay discount hyperbolic model param0.81.01.20.7-1.10.9-1.0-1.0-1.0-1.0-1.0-1.0
Intermittent access intake day 1-15 change0.00.10.5-0.7-0.0-0.30.30.30.30.00.20.1
Intermittent access intake escalation0.00.10.2-0.5-0.4-0.00.10.10.1-0.2-0.1-0.2
Intermittent access intake escalation 20.00.00.3-0.5-0.3-0.10.10.10.1-0.20.0-0.0
Intermitt. access day 1 inactive lever presses0.00.00.0-0.2-0.1-0.00.10.10.2-0.00.00.1
Intermitt. access day 15 inactive lever presses0.21.01.6-1.30.7-1.11.01.01.00.81.00.9
Intermitt. access escalation Index1.54.75.5-2.32.3-2.12.22.22.22.12.22.0
Intermittent access day 1 total infusions2.88.39.1-2.72.7-2.92.82.93.03.03.02.9
Intermittent access day 15 total infusions1.74.16.1-2.51.7-2.12.02.02.11.92.01.9
Intermittent access terminal intake (last 3 days)2.64.66.0-2.41.8-2.22.12.12.22.12.12.0
Intermittent access total infusions4.45.35.7-2.42.1-2.42.32.32.42.32.32.2
Intermittent access day 1 locomotion2.74.95.6-2.22.1-2.32.12.22.22.42.22.2
Intermittent access day 15 total locomotion1.03.75.6-2.41.5-2.11.91.91.91.91.81.8
Intermittent access total locomotion6.88.210.4-3.22.4-3.02.82.82.92.92.82.8
Intermittent access standard deviation0.10.30.7-0.90.5-0.50.50.50.60.40.40.4
Left kidney weight0.42.93.8-1.91.3-1.62.01.71.91.61.51.5
Right kidney weight0.00.20.9-0.90.4-0.50.50.40.50.40.30.3
Cocaine induced anxiety0.00.10.20.2-0.40.2-0.3-0.2-0.2-0.1-0.2-0.1
Post-drug Anxiety0.60.70.80.9-0.90.8-0.9-0.8-0.8-0.8-0.8-0.8
Baseline Anxiety0.20.40.60.7-0.30.6-0.7-0.7-0.6-0.8-0.6-0.8
Tail length0.42.33.31.8-1.51.8-1.4-1.2-1.1-1.6-1.5-1.6
Length with tail1.77.410.33.2-2.73.0-2.6-2.4-2.3-2.7-2.7-2.7
Length without tail1.36.78.32.9-2.42.6-2.7-2.5-2.5-2.5-2.5-2.5
Times rat made contact with spout0.00.00.10.3-0.00.00.00.20.20.00.20.0
Lifetime Intake3.54.44.9-2.12.0-2.12.12.12.22.12.12.0
Liver weight, left0.30.40.6-0.70.6-0.40.70.70.70.70.60.7
Liver weight, right1.11.92.7-1.61.5-1.31.31.31.21.41.31.4
Locomotor activity0.10.20.7-0.90.7-0.40.40.20.10.30.20.2
Locomotor testing distance0.20.51.2-1.11.0-0.60.70.50.50.70.50.7
Locomotor testing rearing0.62.43.2-1.71.8-1.51.41.31.21.71.51.7
Locomotion in novel chamber2.73.65.9-2.41.7-1.91.81.81.81.81.81.8
Locomotion in novel chamber post-restriction0.72.13.4-1.81.3-1.51.41.51.31.41.41.4
Fecal boli incidents, locomotor time 10.10.30.50.3-0.70.4-0.6-0.6-0.7-0.7-0.5-0.6
Change in fecal boli incidents, locomotor task0.40.50.7-0.40.8-0.60.70.70.70.70.70.6
Time >=10cm from walls, locomotor time 11.92.42.8-1.61.3-1.71.51.61.51.61.61.6
Bouts of movement, locomotor time 11.11.41.81.3-1.31.2-1.2-0.9-1.1-1.3-1.0-1.3
Total resting periods, locomotor time 10.70.91.11.0-1.00.9-0.9-0.7-0.9-1.0-0.8-1.0
Rest time, locomotor task time 10.20.30.9-1.00.4-0.60.30.40.40.40.40.5
Distance moved, locomotor task time 10.10.40.5-0.30.7-0.60.70.60.70.60.70.7
Vertical activity count, locomotor time 10.10.50.7-0.80.8-0.70.60.80.70.70.80.7
Time >=10cm from walls, locomotor time 20.00.00.0-0.0-0.20.0-0.1-0.2-0.1-0.1-0.1-0.1
Bouts of movement, locomotor time 20.00.10.40.6-0.40.4-0.4-0.0-0.3-0.2-0.2-0.3
Total resting periods, locomotor time 20.00.00.10.3-0.10.1-0.00.30.10.10.2-0.0
Rest time, locomotor task time 21.11.82.5-1.61.3-1.31.31.31.31.31.31.3
Distance moved, locomotor task time 21.01.41.61.3-1.11.1-1.2-1.2-1.1-1.3-1.2-1.1
Vertical activity count, locomotor time 20.61.31.60.9-1.01.2-1.3-1.1-1.2-1.3-1.2-1.1
Light reinforcement 10.00.00.1-0.30.3-0.2-0.1-0.0-0.00.30.10.3
Light reinforcement 20.00.10.5-0.70.1-0.40.20.20.20.20.20.2
Bone: marrow area2.45.96.8-2.32.2-2.42.52.62.62.42.52.4
Bone: maximum diameter0.20.40.70.4-0.80.5-0.6-0.5-0.6-0.7-0.6-0.7
Bone: maximum force0.40.92.11.5-1.20.9-0.7-0.7-0.5-0.9-0.8-0.9
Bone: maximum moment0.40.71.91.4-1.10.8-0.6-0.7-0.5-0.8-0.7-0.8
Mean time between licks in bursts0.00.20.50.6-0.10.5-0.6-0.7-0.6-0.4-0.5-0.4
Mean num. licks in bursts0.30.91.3-0.70.8-0.70.91.21.10.81.10.9
Cd content in liver0.70.71.3-1.10.7-0.90.70.80.80.90.80.9
Co content in liver0.00.00.1-0.20.10.3-0.1-0.2-0.1-0.3-0.2-0.3
Cu content in liver0.10.10.2-0.30.4-0.50.20.10.20.30.10.3
Fe content in liver0.40.50.70.7-0.60.7-0.7-0.8-0.7-0.6-0.8-0.6
K content in liver0.00.00.20.20.2-0.00.40.20.20.20.00.2
Mg content in liver0.90.91.3-0.91.1-1.01.00.90.91.00.91.0
Mn content in liver2.32.63.81.9-1.71.6-1.4-1.5-1.6-1.5-1.5-1.5
Na content in liver1.71.92.41.1-1.31.3-1.4-1.6-1.5-1.4-1.4-1.4
Rb content in liver2.63.13.9-1.72.0-1.71.71.71.81.71.71.7
Se content in liver0.10.10.1-0.40.2-0.40.30.30.30.30.40.3
Sr content in liver3.63.13.51.8-1.91.8-1.7-1.8-1.8-1.7-1.6-1.7
Zn content in liver0.00.00.10.3-0.10.2-0.0-0.2-0.2-0.2-0.2-0.2
Bone: minimum diameter3.05.86.8-2.22.1-2.42.52.62.62.42.62.4
Time in familiar zone, hab. session 10.30.40.6-0.70.6-0.80.60.30.50.60.50.6
Time in novel zone, hab. session 10.00.00.10.00.10.2-0.30.10.0-0.0-0.0-0.0
Total zone transitions, hab. session 10.20.30.70.7-0.80.5-0.4-0.4-0.4-0.5-0.6-0.5
Total locomotion distance, hab. session 10.40.60.9-0.90.6-0.81.00.90.90.60.70.6
Locomotion velocity, hab. session 10.10.20.4-0.40.2-0.40.70.60.50.20.40.2
Time in familiar zone, hab. session 20.10.20.30.4-0.20.4-0.5-0.5-0.6-0.3-0.4-0.2
Time in novel zone, hab. session 20.30.40.7-0.40.5-0.60.70.70.80.50.50.5
Total zone transitions, hab. session 20.81.01.6-0.30.9-1.10.81.10.91.31.21.2
Total locomotion distance, hab. session 21.52.02.5-1.21.3-1.51.31.61.41.41.51.4
Locomotion velocity, hab. session 21.72.22.8-1.31.4-1.61.41.71.51.51.61.5
Novel to familiar place preference ratio0.20.30.50.6-0.70.4-0.4-0.6-0.5-0.5-0.5-0.5
Novelty place preference0.00.00.10.2-0.30.1-0.1-0.3-0.2-0.1-0.2-0.1
Time in novel zone, NPP test0.00.00.00.1-0.1-0.00.0-0.2-0.10.0-0.1-0.0
Total zone transitions, NPP test0.10.20.80.9-0.60.3-0.2-0.3-0.3-0.4-0.3-0.4
Total locomotion distance, NPP test0.30.40.7-0.40.4-0.60.80.80.70.50.70.4
Locomotion velocity, NPP test0.20.20.4-0.30.2-0.40.70.70.60.30.50.3
Intraocular pressure0.00.00.2-0.3-0.40.2-0.2-0.0-0.2-0.1-0.1-0.1
Delta distance traveled before/after self-admin0.00.00.10.1-0.00.3-0.1-0.1-0.1-0.3-0.2-0.3
Delta ambulatory time before/after self-admin0.10.10.10.3-0.10.4-0.3-0.2-0.3-0.4-0.3-0.4
Parametrial fat weight3.37.79.2-3.02.5-2.72.82.82.92.72.82.7
Pavlov. Cond. lever latency0.00.00.1-0.30.3-0.10.10.1-0.00.20.10.0
Pavlov. Cond. magazine entry latency0.10.10.3-0.30.1-0.50.40.20.40.50.30.5
Pavlov. Cond. change in total contacts0.10.10.2-0.0-0.5-0.1-0.1-0.4-0.2-0.2-0.2-0.1
Pavlov. Cond. index score0.10.10.30.3-0.60.2-0.4-0.4-0.3-0.3-0.4-0.2
Pavlov. Cond. latency score0.00.00.00.0-0.2-0.0-0.1-0.10.0-0.0-0.00.1
Pavlov. Cond. lever contacts0.00.00.1-0.0-0.0-0.10.10.00.20.10.10.2
Pavlov. Cond. magazine entry number0.40.50.9-0.51.0-0.50.70.90.80.60.80.5
Pavlov. Cond. intertrial magazine entries0.00.00.1-0.1-0.20.10.10.10.0-0.3-0.1-0.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.40.3-0.60.2-0.4-0.4-0.3-0.3-0.3-0.2
Pavlov. Cond. response bias0.30.40.70.5-0.80.5-0.6-0.8-0.7-0.6-0.7-0.5
Pavlov. Cond. lever latency0.60.91.3-0.91.2-0.81.00.90.90.90.80.9
Pavlov. Cond. magazine entry latency1.01.42.71.7-1.31.0-1.3-1.0-1.2-1.0-0.9-1.1
Pavlov. Cond. change in total contacts0.30.81.41.0-1.20.6-1.0-0.9-0.9-0.9-0.7-1.0
Pavlov. Cond. index score0.81.32.01.4-1.41.0-1.2-1.0-1.1-1.1-0.9-1.1
Pavlov. Cond. latency score0.81.22.01.3-1.41.0-1.2-0.9-1.0-1.1-0.9-1.1
Pavlov. Cond. lever contacts0.50.71.10.9-1.00.7-1.0-0.8-0.9-0.8-0.7-0.8
Pavlov. Cond. magazine entry number2.53.35.3-2.32.0-1.61.91.61.81.71.51.8
Pavlov. Cond. intertrial magazine entries0.20.51.1-1.10.7-0.80.70.50.60.70.60.7
Pavlov. Cond. lever-magazine prob. diff.1.01.52.41.6-1.51.1-1.3-1.1-1.2-1.2-0.9-1.2
Pavlov. Cond. response bias0.81.21.61.3-1.20.9-1.3-1.1-1.2-1.0-0.8-1.0
Time in closed arm before self-admin0.40.60.8-0.90.6-0.90.60.90.70.80.80.9
Time in closed arm after self-admin0.20.20.4-0.40.4-0.40.60.60.60.40.40.4
Time in open arm before self-admin0.10.10.5-0.20.7-0.10.50.20.20.20.10.1
Time in open arm after self-admin0.10.10.20.4-0.10.3-0.4-0.4-0.4-0.2-0.2-0.2
Bone: periosteal estimation0.10.20.4-0.40.1-0.50.60.60.60.40.60.4
Bone: periosteal perimeter0.00.10.2-0.20.1-0.40.30.30.40.10.20.1
Bone: post-yield work2.13.54.6-1.41.5-2.12.01.92.01.92.01.9
Progressive ratio test 1 active lever presses0.10.20.3-0.50.4-0.50.40.30.50.50.40.3
Progressive ratio test 1 breakpoint0.10.10.2-0.40.3-0.40.30.20.40.40.30.2
Progressive ratio test 1 inactive lever presses0.00.00.1-0.20.1-0.20.10.10.20.10.20.1
Progressive ratio test 2 active lever presses1.21.62.5-1.61.1-1.41.21.21.21.31.31.2
Progressive ratio test 2 breakpoint1.11.42.2-1.51.0-1.31.11.11.11.11.21.1
Progressive ratio test 2 inactive lever presses2.27.19.8-3.12.3-2.72.52.62.62.62.82.6
Incentive Sensitization - Responses0.10.20.3-0.40.3-0.60.40.50.40.40.50.4
Incentive Sensitization - Breakpoint0.10.30.5-0.60.4-0.70.50.60.50.50.60.5
Sum of active levers in priming session hrs 5-68.27.79.52.2-3.12.5-2.7-3.0-2.8-2.9-2.8-2.9
Progressive ratio0.41.11.4-0.40.9-1.01.11.21.21.11.01.1
Food seeking constrained by brief footshock0.10.10.20.4-0.30.3-0.2-0.2-0.2-0.3-0.3-0.3
Seeking ratio, punishment vs. effort0.10.10.2-0.1-0.10.4-0.3-0.4-0.4-0.4-0.3-0.4
Retroperitoneal fat weight6.026.837.4-6.15.3-5.05.05.15.05.05.04.9
Reaction time number correct0.41.41.81.0-1.11.1-1.1-1.2-1.3-1.2-1.3-1.3
Reaction time mean minus median0.53.14.21.9-2.01.6-1.8-1.8-1.8-1.6-1.6-1.7
Reaction time mean minus median AUC0.42.93.71.8-1.91.6-1.8-1.7-1.6-1.6-1.6-1.6
Reaction time num false alarms0.00.00.1-0.00.30.20.10.20.2-0.2-0.1-0.1
Reaction time num false alarms AUC0.10.20.40.6-0.20.7-0.3-0.2-0.2-0.6-0.5-0.4
Reaction time trials correct on left0.41.41.81.0-1.11.1-1.1-1.2-1.3-1.2-1.3-1.3
Reaction time trials on left0.51.72.21.1-1.21.2-1.3-1.3-1.5-1.3-1.4-1.4
Reaction time mean0.00.10.30.1-0.50.1-0.5-0.3-0.3-0.0-0.2-0.0
Reaction time mean AUC0.00.00.20.0-0.4-0.0-0.4-0.1-0.20.1-0.00.1
Median of all reaction times0.10.20.4-0.50.2-0.50.10.30.30.60.40.6
Reaction time omissions1.32.12.91.7-1.61.4-1.6-1.4-1.4-1.3-1.4-1.2
Reaction time false alarm rate0.10.20.4-0.10.5-0.00.50.50.60.20.30.4
Reaction time premature initiation rate1.42.23.11.8-1.01.4-1.5-1.7-1.6-1.3-1.6-1.4
Reaction time premature initiations1.95.86.72.6-1.92.3-2.4-2.6-2.6-2.3-2.6-2.3
Std. dev. reaction times0.31.01.61.1-1.30.9-1.2-1.0-1.0-0.8-0.9-0.8
Reaction time trials completed0.51.72.21.1-1.21.2-1.3-1.3-1.5-1.3-1.4-1.4
Reaction time trials AUC0.41.31.70.9-1.01.0-1.1-1.2-1.3-1.1-1.3-1.2
Run reversals in cocaine runway, females0.30.30.6-0.20.8-0.50.70.60.60.60.60.6
Run reversals in cocaine runway, males1.01.11.30.7-1.11.1-1.0-1.1-1.1-1.1-1.1-1.1
Latency to leave start box in cocaine runway0.60.80.9-0.80.8-1.00.90.90.91.00.91.0
Latency to leave start box in cocaine runway, F0.40.50.7-0.60.7-0.80.70.70.70.80.70.8
Latency to leave start box in cocaine runway, M0.00.00.00.0-0.1-0.1-0.00.00.10.00.00.0
Std. dev. time between licks in bursts0.10.10.20.30.10.4-0.4-0.4-0.4-0.3-0.2-0.3
Total sessions with >9 infusions0.60.70.9-0.60.9-0.90.90.80.90.90.90.8
Short access day 1 total inactive lever presses1.02.12.8-1.71.5-1.51.41.41.41.41.51.4
Short access day 10 total inactive lever presses0.00.20.3-0.50.5-0.30.60.60.50.30.40.4
Short access day 1 total infusions1.83.64.0-1.91.9-1.91.91.92.01.81.91.7
Short access day 10 total infusions2.54.04.5-1.61.9-2.12.12.02.12.12.12.0
Short access total infusions1.72.42.7-1.31.6-1.61.61.51.61.61.61.5
Short access day 1 locomotion1.22.02.4-1.51.4-1.51.51.41.41.41.41.2
Short access day 10 total locomotion0.52.12.5-1.51.3-1.61.61.51.51.41.31.4
Short access total locomotion1.62.32.8-1.61.5-1.71.61.41.51.51.51.4
One hour access (0.3 mA shock)4.45.26.7-2.62.2-2.22.22.32.32.12.32.2
Compulsive drug intake1.62.33.21.8-1.21.7-1.6-1.5-1.6-1.5-1.4-1.3
One hour access (shock baseline)2.25.78.4-2.92.1-2.52.42.32.42.22.32.2
Social response proportion0.10.20.30.5-0.40.3-0.4-0.3-0.4-0.4-0.4-0.4
Social responses0.30.30.40.6-0.50.6-0.6-0.6-0.6-0.5-0.6-0.5
Social time0.30.50.80.8-0.70.7-0.9-0.7-0.8-0.6-0.7-0.6
Soleus weight1.95.68.7-2.92.3-2.22.52.42.52.12.12.1
Bone: stiffness0.10.20.80.9-0.70.3-0.5-0.4-0.3-0.3-0.3-0.3
Tibialis anterior weight9.633.141.96.5-5.95.9-5.5-5.4-5.3-5.8-5.6-5.8
Time to tail flick, vehicle, before self-admin0.10.10.2-0.10.2-0.30.40.40.40.30.30.0
Time to tail flick, vehicle, after self-admin0.40.81.2-0.30.9-0.71.10.91.00.90.90.9
Time to tail flick, test, before self-admin4.14.76.1-2.02.4-2.12.52.22.32.02.02.0
Time to tail flick, test, after self-admin0.10.10.20.2-0.30.3-0.3-0.2-0.2-0.3-0.3-0.4
Delta time to tail flick, vehicle, before/after SA0.10.10.20.10.4-0.20.40.20.30.30.30.5
Delta time to tail flick, test, before/after SA5.56.88.02.3-2.82.6-2.8-2.6-2.7-2.5-2.5-2.5
Tibia length1.74.87.32.1-2.72.1-2.3-2.0-2.2-2.1-2.1-2.0
Ambulatory time before self-admin0.00.00.10.1-0.3-0.1-0.0-0.1-0.10.10.00.1
Ambulatory time after self-admin0.40.60.7-0.80.5-0.80.80.80.80.70.70.8
Bone: tissue strength0.00.00.1-0.20.2-0.30.30.10.20.10.10.1
Total heroin consumption3.23.74.92.2-1.81.8-1.9-2.0-2.0-1.8-1.9-1.9
Bone: trabecular number0.20.40.6-0.10.4-0.70.50.60.60.80.70.8
Bone: trabecular spacing0.00.10.2-0.40.4-0.20.10.20.20.30.30.3
Bone: trabecular thickness1.01.51.9-1.21.2-1.41.11.21.11.31.11.3
Bone: trabecular tissue density0.61.12.7-1.60.8-0.91.01.11.20.71.00.8
Water consumed over 24 hours0.30.50.90.9-0.70.7-1.0-0.7-0.6-0.6-0.6-0.7
Number of responses in last shaping day0.00.00.10.10.10.1-0.3-0.2-0.1-0.0-0.1-0.2