Hub : Genes

LOC120099979

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression LOC120099979 0.16 0.09 1.6e-13 0.12 0.16 0.15 0.15 1.6e-09 9.0e-13 8.9e-12 3.0e-12
2 Brain gene expression LOC120099979 0.44 0.11 0.0e+00 0.39 0.37 0.39 0.39 1.8e-38 2.2e-36 9.6e-39 5.3e-38
3 NAcc gene expression LOC120099979 0.11 0.06 5.6e-17 0.12 0.12 0.12 0.12 4.9e-17 1.1e-17 1.1e-17 2.0e-17
4 OFC gene expression LOC120099979 0.32 0.14 1.6e-06 0.25 0.14 0.22 0.06 1.0e-06 2.8e-04 5.5e-06 1.4e-02
5 LHb gene expression LOC120099979 0.22 0.12 1.8e-04 0.2 0.15 0.11 0.06 2.2e-05 2.2e-04 1.4e-03 1.4e-02
6 BLA gene expression LOC120099979 0.22 0.11 9.7e-09 0.16 0.14 0.13 0.14 8.7e-09 1.1e-07 3.4e-07 6.4e-08
7 IC gene expression LOC120099979 0.33 0.19 6.4e-09 0.21 0.18 0.16 0.2 4.8e-09 3.6e-08 2.3e-07 7.4e-09
8 PL gene expression LOC120099979 0.19 0.09 0.0e+00 0.22 0.2 0.21 0.21 3.6e-23 5.3e-22 2.4e-22 1.3e-22
9 IL gene expression LOC120099979 0.36 0.16 2.0e-06 0.23 0.17 0.21 0.08 2.9e-06 5.9e-05 1.0e-05 5.4e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.71.11.6-0.5-0.9-1.1-1.0-1.1-1.1-1.3-1.1-1.2
Area under the delay curve1.21.41.7-0.9-1.3-1.1-1.2-1.3-1.2-1.1-1.2-1.1
BMI with tail0.31.01.40.1-0.8-1.1-1.1-1.1-1.1-1.1-1.1-1.2
BMI without tail0.20.71.00.2-0.7-0.6-1.0-1.0-1.0-0.9-0.9-0.9
Body weight0.41.85.42.31.51.41.10.90.91.21.21.2
Weight adjusted by age1.62.53.01.61.71.51.51.51.51.61.61.6
Bone surface0.30.62.21.51.10.60.60.60.50.50.60.5
Bone volume0.00.10.20.40.3-0.2-0.1-0.2-0.2-0.3-0.2-0.3
Breakpoint value in progressive ratio session2.02.43.21.81.71.41.51.51.41.51.41.6
Number of licking bursts0.20.40.60.60.50.40.70.80.70.50.70.6
Context. condit. distance diff. score1.51.82.3-1.5-1.5-1.3-1.5-1.4-1.5-1.2-1.2-1.2
Locomotion velocity, session 10.10.10.10.20.40.30.10.30.30.10.20.1
Locomotion distance, session 10.30.40.7-0.2-0.6-0.7-0.8-0.6-0.6-0.8-0.6-0.7
Locomotion velocity, session 20.70.81.61.31.00.80.80.80.90.60.80.7
Locomotion distance, session 20.10.10.20.2-0.1-0.2-0.4-0.4-0.3-0.4-0.5-0.4
Locomotion velocity, session 30.50.60.8-0.7-0.8-0.9-0.7-0.9-0.8-0.8-0.8-0.7
Locomotion distance, session 30.00.00.0-0.1-0.0-0.1-0.0-0.1-0.1-0.1-0.1-0.1
Stereotopy head waving bouts, day 32.02.32.6-1.4-1.6-1.5-1.5-1.6-1.5-1.5-1.5-1.5
Stereotopy head waving duration, day 31.92.32.5-1.5-1.6-1.5-1.4-1.6-1.5-1.5-1.5-1.5
Locomotion velocity, session 71.31.41.9-1.0-1.2-1.2-1.4-1.2-1.4-1.2-1.1-1.1
Locomotion distance, session 70.40.50.8-0.3-0.8-0.5-0.8-0.9-0.9-0.6-0.6-0.5
Stereotopy head waving bouts, day 70.30.40.5-0.6-0.4-0.7-0.6-0.6-0.5-0.6-0.6-0.7
Stereotopy head waving duration, day 70.00.00.10.20.1-0.20.00.00.1-0.2-0.1-0.3
Locomotion velocity, session 80.60.71.31.10.81.00.90.80.70.70.80.7
Locomotion distance, session 80.60.81.2-0.9-0.8-0.9-1.1-0.9-1.0-0.8-0.8-0.8
Degree of sensitization distance0.40.50.7-0.4-0.8-0.6-0.8-0.7-0.8-0.6-0.6-0.6
Degree of sensitization stereotypy0.10.10.30.40.60.20.20.30.30.30.30.2
Conditioned locomotion1.11.32.31.51.21.40.90.90.91.11.11.2
Cocaine response after cond. corrected0.60.81.1-1.0-1.0-0.7-1.0-1.0-1.0-0.7-0.7-0.7
Cocaine response after cond. not corrected0.40.50.8-0.9-0.9-0.7-0.7-0.7-0.7-0.6-0.6-0.5
Cocaine response before conditioning0.60.71.30.70.90.61.11.01.10.60.70.7
Saline control response1.31.73.31.81.31.31.31.21.21.11.21.2
Bone: connectivity density0.10.20.30.6-0.2-0.3-0.4-0.4-0.4-0.5-0.4-0.4
Bone: cortical apparent density0.40.50.70.70.70.80.60.90.70.70.80.7
Bone: cortical area1.11.62.11.31.51.31.21.31.21.31.21.3
Bone: cortical porosity0.20.20.3-0.2-0.4-0.5-0.3-0.3-0.1-0.6-0.5-0.6
Bone: cortical porosity0.00.00.10.1-0.1-0.2-0.0-0.10.1-0.4-0.3-0.4
Bone: cortical thickness5.59.29.83.12.93.12.93.12.93.13.03.1
Bone: cortical thickness1.61.92.21.41.11.41.41.51.41.31.41.3
Bone: cortical tissue density0.60.71.00.90.80.90.81.00.90.80.90.8
Condit. Reinf. active minus inactive responses0.00.00.10.20.20.0-0.20.0-0.00.20.00.1
Condit. Reinf. active-inactive response ratio0.00.00.10.00.1-0.0-0.20.1-0.00.10.00.0
Condit. Reinf. active responses0.00.00.20.10.3-0.0-0.4-0.1-0.20.2-0.00.1
Condit. Reinf. inactive responses0.10.10.4-0.2-0.1-0.3-0.6-0.6-0.5-0.2-0.4-0.2
Incentive salience index mean0.00.00.10.20.2-0.0-0.4-0.1-0.20.1-0.10.0
Condit. Reinf. lever presses0.20.30.60.60.70.50.10.30.10.70.40.6
Condit. Reinf. active minus inactive responses0.20.20.5-0.6-0.4-0.7-0.3-0.4-0.4-0.3-0.5-0.3
Condit. Reinf. active-inactive response ratio0.40.51.0-1.0-0.5-0.9-0.6-0.7-0.8-0.5-0.6-0.5
Condit. Reinf. active responses0.20.30.6-0.5-0.6-0.8-0.3-0.4-0.3-0.6-0.5-0.4
Condit. Reinf. inactive responses0.20.20.6-0.0-0.7-0.6-0.1-0.2-0.1-0.8-0.3-0.5
Condit. Reinf. lever presses0.60.91.31.21.00.71.00.90.90.90.80.9
Condit. Reinf. lever reinforcers received0.00.10.2-0.1-0.3-0.50.0-0.1-0.1-0.3-0.2-0.1
Conditioned reinforcement - actives0.30.50.90.40.90.50.80.80.80.70.70.8
Conditioned reinforcement - inactives0.81.12.3-1.5-0.6-1.1-0.9-1.0-1.1-0.9-1.1-1.0
Conditioned locomotion2.43.26.5-2.5-1.6-1.8-1.6-1.7-1.7-1.7-1.6-1.7
Patch foraging indifference point 0 sec0.10.20.4-0.5-0.6-0.6-0.4-0.4-0.4-0.2-0.4-0.3
Patch foraging indifference point AUC2.13.03.81.91.91.71.61.71.71.61.71.6
Delay disc. indifference point, 0s delay2.93.23.8-1.5-1.9-1.6-1.8-1.9-1.8-1.8-1.8-1.8
Delay disc. indifference point, 16s delay1.21.31.4-1.2-1.1-1.2-1.1-1.2-1.2-1.2-1.1-1.2
Delay disc. indifference point, 2s delay0.40.50.6-0.7-0.7-0.8-0.7-0.6-0.5-0.7-0.7-0.7
Delay disc. indifference point, 24s delay0.00.00.1-0.1-0.30.0-0.2-0.2-0.2-0.1-0.1-0.1
Delay disc. indifference point, 4s delay1.41.41.9-0.9-1.4-1.1-1.3-1.2-1.2-1.2-1.3-1.2
Delay disc. indifference point, 8s delay0.91.01.5-0.7-1.2-0.9-1.0-1.2-1.2-0.9-1.1-0.9
Indifference point function ln k3.45.99.3-3.0-2.6-2.4-2.2-2.4-2.3-2.1-2.4-2.2
Indifference point function log k3.45.99.3-3.0-2.6-2.4-2.2-2.4-2.3-2.1-2.4-2.2
Patch foraging total patch changes 0 sec0.00.00.1-0.1-0.2-0.1-0.0-0.10.00.2-0.00.1
Patch foraging total patch changes 12 sec1.72.24.02.01.31.41.31.51.31.41.51.4
Patch foraging total patch changes 18 sec0.10.10.30.50.40.30.40.40.40.30.50.4
Patch foraging total patch changes 24 sec1.52.53.01.71.41.51.41.51.51.71.71.7
Patch foraging total patch changes 6 sec0.30.40.91.00.30.60.50.60.50.70.70.7
Patch foraging time to switch 0 sec0.10.10.20.50.2-0.2-0.2-0.3-0.3-0.4-0.3-0.4
Patch foraging water rate 0 sec0.10.31.5-1.2-0.6-0.3-0.4-0.4-0.40.1-0.20.1
Patch foraging water rate 12 sec1.12.35.5-2.3-1.9-1.4-1.4-1.2-1.2-1.3-1.4-1.3
Patch foraging water rate 18 sec0.61.02.1-1.4-1.4-0.9-0.9-0.8-0.8-0.8-0.8-0.8
Patch foraging water rate 24 sec0.50.72.0-1.4-1.0-0.6-0.8-0.8-0.9-0.6-0.8-0.6
Patch foraging water rate 6 sec0.30.51.6-1.3-1.0-0.5-0.6-0.6-0.7-0.3-0.5-0.2
Seeking ratio, delayed vs. immediate footshock0.80.91.1-0.8-0.9-1.0-1.1-0.9-0.9-1.0-1.0-1.0
Distance traveled before self-admin0.00.00.10.20.3-0.00.00.10.10.00.1-0.0
Distance traveled after self-admin0.10.10.20.40.50.30.20.20.20.40.40.4
Extensor digitorum longus weight4.316.926.55.24.34.33.73.73.54.13.94.1
Bone: elastic displacement0.30.30.50.20.30.70.20.50.50.70.60.7
Bone: elastic work1.82.33.11.71.31.81.21.41.31.71.51.7
Bone: endosteal estimation2.55.46.2-2.2-2.0-2.3-2.4-2.5-2.5-2.3-2.4-2.3
Bone: endosteal perimeter2.85.96.6-2.5-2.1-2.6-2.4-2.5-2.5-2.4-2.5-2.3
Epididymis fat weight1.75.79.9-3.1-2.2-2.4-2.4-2.3-2.2-2.3-2.2-2.3
Delta time in closed arm before/after self-admin0.10.10.20.5-0.10.4-0.00.10.10.20.20.3
Delta time in open arm before/after self-admin0.40.40.80.50.90.50.70.60.60.50.40.5
Diff in mean of infusions in LGA sessions0.81.01.21.11.01.00.91.11.00.90.91.0
Delay discount exponential model param0.80.91.20.71.10.91.01.01.00.91.00.9
Extinction: sum of active levers before priming0.50.61.21.10.80.60.70.80.70.70.60.8
Active lever presses in extinction session 63.33.34.21.82.11.71.91.71.81.81.71.9
Bone: final force0.91.42.61.61.41.21.01.00.81.11.01.2
Bone: final moment0.81.22.31.51.31.21.00.90.81.10.91.1
Food consumed during 24 hour testing period0.60.81.20.61.00.81.11.00.90.90.90.9
Glucose5.18.18.6-2.8-2.7-2.9-2.8-2.9-2.8-2.9-2.9-2.9
Heart weight4.87.49.1-2.3-3.0-2.6-2.8-2.7-2.8-2.8-2.7-2.7
Delay discount hyperbolic model param0.91.01.20.71.10.91.01.01.01.01.01.0
Intermittent access intake day 1-15 change0.10.10.5-0.70.0-0.3-0.3-0.3-0.3-0.0-0.2-0.1
Intermittent access intake escalation0.00.10.2-0.50.4-0.0-0.1-0.1-0.10.20.10.2
Intermittent access intake escalation 20.00.00.3-0.50.3-0.1-0.1-0.1-0.10.2-0.00.0
Intermitt. access day 1 inactive lever presses0.00.00.0-0.20.1-0.0-0.1-0.1-0.20.0-0.0-0.1
Intermitt. access day 15 inactive lever presses0.51.01.6-1.3-0.7-1.1-1.0-1.0-1.0-0.8-1.0-0.9
Intermitt. access escalation Index3.44.75.5-2.3-2.3-2.1-2.2-2.2-2.2-2.1-2.2-2.0
Intermittent access day 1 total infusions5.28.39.1-2.7-2.7-2.9-2.8-2.9-3.0-3.0-3.0-2.9
Intermittent access day 15 total infusions2.84.16.1-2.5-1.7-2.1-2.0-2.0-2.1-1.9-2.0-1.9
Intermittent access terminal intake (last 3 days)3.54.66.0-2.4-1.8-2.2-2.1-2.1-2.2-2.1-2.1-2.0
Intermittent access total infusions4.45.35.7-2.4-2.1-2.4-2.3-2.3-2.4-2.3-2.3-2.2
Intermittent access day 1 locomotion3.84.95.6-2.2-2.1-2.3-2.1-2.2-2.2-2.4-2.2-2.2
Intermittent access day 15 total locomotion2.13.75.6-2.4-1.5-2.1-1.9-1.9-1.9-1.9-1.8-1.8
Intermittent access total locomotion6.88.210.4-3.2-2.4-3.0-2.8-2.8-2.9-2.9-2.8-2.8
Intermittent access standard deviation0.10.30.7-0.9-0.5-0.5-0.5-0.5-0.6-0.4-0.4-0.4
Left kidney weight0.62.93.8-1.9-1.3-1.6-2.0-1.7-1.9-1.6-1.5-1.5
Right kidney weight0.10.20.9-0.9-0.4-0.5-0.5-0.4-0.5-0.4-0.3-0.3
Cocaine induced anxiety0.00.10.20.20.40.20.30.20.20.10.20.1
Post-drug Anxiety0.60.70.80.90.90.80.90.80.80.80.80.8
Baseline Anxiety0.40.40.60.70.30.60.70.70.60.80.60.8
Tail length0.62.33.31.81.51.81.41.21.11.61.51.6
Length with tail1.77.410.33.22.73.02.62.42.32.72.72.7
Length without tail2.16.78.32.92.42.62.72.52.52.52.52.5
Times rat made contact with spout0.00.00.10.30.00.0-0.0-0.2-0.2-0.0-0.2-0.0
Lifetime Intake3.64.44.9-2.1-2.0-2.1-2.1-2.1-2.2-2.1-2.1-2.0
Liver weight, left0.30.40.6-0.7-0.6-0.4-0.7-0.7-0.7-0.7-0.6-0.7
Liver weight, right1.11.92.7-1.6-1.5-1.3-1.3-1.3-1.2-1.4-1.3-1.4
Locomotor activity0.10.20.7-0.9-0.7-0.4-0.4-0.2-0.1-0.3-0.2-0.2
Locomotor testing distance0.30.51.2-1.1-1.0-0.6-0.7-0.5-0.5-0.7-0.5-0.7
Locomotor testing rearing1.22.43.2-1.7-1.8-1.5-1.4-1.3-1.2-1.7-1.5-1.7
Locomotion in novel chamber2.83.65.9-2.4-1.7-1.9-1.8-1.8-1.8-1.8-1.8-1.8
Locomotion in novel chamber post-restriction1.32.13.4-1.8-1.3-1.5-1.4-1.5-1.3-1.4-1.4-1.4
Fecal boli incidents, locomotor time 10.20.30.50.30.70.40.60.60.70.70.50.6
Change in fecal boli incidents, locomotor task0.50.50.7-0.4-0.8-0.6-0.7-0.7-0.7-0.7-0.7-0.6
Time >=10cm from walls, locomotor time 12.32.42.8-1.6-1.3-1.7-1.5-1.6-1.5-1.6-1.6-1.6
Bouts of movement, locomotor time 11.31.41.81.31.31.21.20.91.11.31.01.3
Total resting periods, locomotor time 10.80.91.11.01.00.90.90.70.91.00.81.0
Rest time, locomotor task time 10.20.30.9-1.0-0.4-0.6-0.3-0.4-0.4-0.4-0.4-0.5
Distance moved, locomotor task time 10.30.40.5-0.3-0.7-0.6-0.7-0.6-0.7-0.6-0.7-0.7
Vertical activity count, locomotor time 10.20.50.7-0.8-0.8-0.7-0.6-0.8-0.7-0.7-0.8-0.7
Time >=10cm from walls, locomotor time 20.00.00.0-0.00.20.00.10.20.10.10.10.1
Bouts of movement, locomotor time 20.10.10.40.60.40.40.40.00.30.20.20.3
Total resting periods, locomotor time 20.00.00.10.30.10.10.0-0.3-0.1-0.1-0.20.0
Rest time, locomotor task time 21.41.82.5-1.6-1.3-1.3-1.3-1.3-1.3-1.3-1.3-1.3
Distance moved, locomotor task time 21.21.41.61.31.11.11.21.21.11.31.21.1
Vertical activity count, locomotor time 20.91.31.60.91.01.21.31.11.21.31.21.1
Light reinforcement 10.00.00.1-0.3-0.3-0.20.10.00.0-0.3-0.1-0.3
Light reinforcement 20.10.10.5-0.7-0.1-0.4-0.2-0.2-0.2-0.2-0.2-0.2
Bone: marrow area2.75.96.8-2.3-2.2-2.4-2.5-2.6-2.6-2.4-2.5-2.4
Bone: maximum diameter0.20.40.70.40.80.50.60.50.60.70.60.7
Bone: maximum force0.50.92.11.51.20.90.70.70.50.90.80.9
Bone: maximum moment0.40.71.91.41.10.80.60.70.50.80.70.8
Mean time between licks in bursts0.10.20.50.60.10.50.60.70.60.40.50.4
Mean num. licks in bursts0.60.91.3-0.7-0.8-0.7-0.9-1.2-1.1-0.8-1.1-0.9
Cd content in liver0.70.71.3-1.1-0.7-0.9-0.7-0.8-0.8-0.9-0.8-0.9
Co content in liver0.00.00.1-0.2-0.10.30.10.20.10.30.20.3
Cu content in liver0.10.10.2-0.3-0.4-0.5-0.2-0.1-0.2-0.3-0.1-0.3
Fe content in liver0.40.50.70.70.60.70.70.80.70.60.80.6
K content in liver0.00.00.20.2-0.2-0.0-0.4-0.2-0.2-0.2-0.0-0.2
Mg content in liver0.90.91.3-0.9-1.1-1.0-1.0-0.9-0.9-1.0-0.9-1.0
Mn content in liver2.32.63.81.91.71.61.41.51.61.51.51.5
Na content in liver1.81.92.41.11.31.31.41.61.51.41.41.4
Rb content in liver2.63.13.9-1.7-2.0-1.7-1.7-1.7-1.8-1.7-1.7-1.7
Se content in liver0.10.10.1-0.4-0.2-0.4-0.3-0.3-0.3-0.3-0.4-0.3
Sr content in liver3.63.13.51.81.91.81.71.81.81.71.61.7
Zn content in liver0.00.00.10.30.10.20.00.20.20.20.20.2
Bone: minimum diameter3.25.86.8-2.2-2.1-2.4-2.5-2.6-2.6-2.4-2.6-2.4
Time in familiar zone, hab. session 10.40.40.6-0.7-0.6-0.8-0.6-0.3-0.5-0.6-0.5-0.6
Time in novel zone, hab. session 10.00.00.10.0-0.10.20.3-0.1-0.00.00.00.0
Total zone transitions, hab. session 10.20.30.70.70.80.50.40.40.40.50.60.5
Total locomotion distance, hab. session 10.40.60.9-0.9-0.6-0.8-1.0-0.9-0.9-0.6-0.7-0.6
Locomotion velocity, hab. session 10.10.20.4-0.4-0.2-0.4-0.7-0.6-0.5-0.2-0.4-0.2
Time in familiar zone, hab. session 20.20.20.30.40.20.40.50.50.60.30.40.2
Time in novel zone, hab. session 20.30.40.7-0.4-0.5-0.6-0.7-0.7-0.8-0.5-0.5-0.5
Total zone transitions, hab. session 20.81.01.6-0.3-0.9-1.1-0.8-1.1-0.9-1.3-1.2-1.2
Total locomotion distance, hab. session 21.52.02.5-1.2-1.3-1.5-1.3-1.6-1.4-1.4-1.5-1.4
Locomotion velocity, hab. session 21.72.22.8-1.3-1.4-1.6-1.4-1.7-1.5-1.5-1.6-1.5
Novel to familiar place preference ratio0.30.30.50.60.70.40.40.60.50.50.50.5
Novelty place preference0.00.00.10.20.30.10.10.30.20.10.20.1
Time in novel zone, NPP test0.00.00.00.10.1-0.0-0.00.20.1-0.00.10.0
Total zone transitions, NPP test0.10.20.80.90.60.30.20.30.30.40.30.4
Total locomotion distance, NPP test0.30.40.7-0.4-0.4-0.6-0.8-0.8-0.7-0.5-0.7-0.4
Locomotion velocity, NPP test0.20.20.4-0.3-0.2-0.4-0.7-0.7-0.6-0.3-0.5-0.3
Intraocular pressure0.00.00.2-0.30.40.20.20.00.20.10.10.1
Delta distance traveled before/after self-admin0.00.00.10.10.00.30.10.10.10.30.20.3
Delta ambulatory time before/after self-admin0.10.10.10.30.10.40.30.20.30.40.30.4
Parametrial fat weight3.37.79.2-3.0-2.5-2.7-2.8-2.8-2.9-2.7-2.8-2.7
Pavlov. Cond. lever latency0.00.00.1-0.3-0.3-0.1-0.1-0.10.0-0.2-0.1-0.0
Pavlov. Cond. magazine entry latency0.10.10.3-0.3-0.1-0.5-0.4-0.2-0.4-0.5-0.3-0.5
Pavlov. Cond. change in total contacts0.10.10.2-0.00.5-0.10.10.40.20.20.20.1
Pavlov. Cond. index score0.10.10.30.30.60.20.40.40.30.30.40.2
Pavlov. Cond. latency score0.00.00.00.00.2-0.00.10.1-0.00.00.0-0.1
Pavlov. Cond. lever contacts0.00.00.1-0.00.0-0.1-0.1-0.0-0.2-0.1-0.1-0.2
Pavlov. Cond. magazine entry number0.40.50.9-0.5-1.0-0.5-0.7-0.9-0.8-0.6-0.8-0.5
Pavlov. Cond. intertrial magazine entries0.00.00.1-0.10.20.1-0.1-0.1-0.00.30.10.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.40.30.60.20.40.40.30.30.30.2
Pavlov. Cond. response bias0.30.40.70.50.80.50.60.80.70.60.70.5
Pavlov. Cond. lever latency0.60.91.3-0.9-1.2-0.8-1.0-0.9-0.9-0.9-0.8-0.9
Pavlov. Cond. magazine entry latency1.21.42.71.71.31.01.31.01.21.00.91.1
Pavlov. Cond. change in total contacts0.50.81.41.01.20.61.00.90.90.90.71.0
Pavlov. Cond. index score1.01.32.01.41.41.01.21.01.11.10.91.1
Pavlov. Cond. latency score0.91.22.01.31.41.01.20.91.01.10.91.1
Pavlov. Cond. lever contacts0.50.71.10.91.00.71.00.80.90.80.70.8
Pavlov. Cond. magazine entry number2.63.35.3-2.3-2.0-1.6-1.9-1.6-1.8-1.7-1.5-1.8
Pavlov. Cond. intertrial magazine entries0.30.51.1-1.1-0.7-0.8-0.7-0.5-0.6-0.7-0.6-0.7
Pavlov. Cond. lever-magazine prob. diff.1.11.52.41.61.51.11.31.11.21.20.91.2
Pavlov. Cond. response bias0.91.21.61.31.20.91.31.11.21.00.81.0
Time in closed arm before self-admin0.50.60.8-0.9-0.6-0.9-0.6-0.9-0.7-0.8-0.8-0.9
Time in closed arm after self-admin0.20.20.4-0.4-0.4-0.4-0.6-0.6-0.6-0.4-0.4-0.4
Time in open arm before self-admin0.10.10.5-0.2-0.7-0.1-0.5-0.2-0.2-0.2-0.1-0.1
Time in open arm after self-admin0.10.10.20.40.10.30.40.40.40.20.20.2
Bone: periosteal estimation0.10.20.4-0.4-0.1-0.5-0.6-0.6-0.6-0.4-0.6-0.4
Bone: periosteal perimeter0.00.10.2-0.2-0.1-0.4-0.3-0.3-0.4-0.1-0.2-0.1
Bone: post-yield work2.43.54.6-1.4-1.5-2.1-2.0-1.9-2.0-1.9-2.0-1.9
Progressive ratio test 1 active lever presses0.10.20.3-0.5-0.4-0.5-0.4-0.3-0.5-0.5-0.4-0.3
Progressive ratio test 1 breakpoint0.10.10.2-0.4-0.3-0.4-0.3-0.2-0.4-0.4-0.3-0.2
Progressive ratio test 1 inactive lever presses0.00.00.1-0.2-0.1-0.2-0.1-0.1-0.2-0.1-0.2-0.1
Progressive ratio test 2 active lever presses1.41.62.5-1.6-1.1-1.4-1.2-1.2-1.2-1.3-1.3-1.2
Progressive ratio test 2 breakpoint1.21.42.2-1.5-1.0-1.3-1.1-1.1-1.1-1.1-1.2-1.1
Progressive ratio test 2 inactive lever presses4.47.19.8-3.1-2.3-2.7-2.5-2.6-2.6-2.6-2.8-2.6
Incentive Sensitization - Responses0.10.20.3-0.4-0.3-0.6-0.4-0.5-0.4-0.4-0.5-0.4
Incentive Sensitization - Breakpoint0.20.30.5-0.6-0.4-0.7-0.5-0.6-0.5-0.5-0.6-0.5
Sum of active levers in priming session hrs 5-68.37.79.52.23.12.52.73.02.82.92.82.9
Progressive ratio0.71.11.4-0.4-0.9-1.0-1.1-1.2-1.2-1.1-1.0-1.1
Food seeking constrained by brief footshock0.10.10.20.40.30.30.20.20.20.30.30.3
Seeking ratio, punishment vs. effort0.10.10.2-0.10.10.40.30.40.40.40.30.4
Retroperitoneal fat weight6.326.837.4-6.1-5.3-5.0-5.0-5.1-5.0-5.0-5.0-4.9
Reaction time number correct0.71.41.81.01.11.11.11.21.31.21.31.3
Reaction time mean minus median1.23.14.21.92.01.61.81.81.81.61.61.7
Reaction time mean minus median AUC1.12.93.71.81.91.61.81.71.61.61.61.6
Reaction time num false alarms0.00.00.1-0.0-0.30.2-0.1-0.2-0.20.20.10.1
Reaction time num false alarms AUC0.10.20.40.60.20.70.30.20.20.60.50.4
Reaction time trials correct on left0.71.41.81.01.11.11.11.21.31.21.31.3
Reaction time trials on left0.91.72.21.11.21.21.31.31.51.31.41.4
Reaction time mean0.10.10.30.10.50.10.50.30.30.00.20.0
Reaction time mean AUC0.00.00.20.00.4-0.00.40.10.2-0.10.0-0.1
Median of all reaction times0.10.20.4-0.5-0.2-0.5-0.1-0.3-0.3-0.6-0.4-0.6
Reaction time omissions1.52.12.91.71.61.41.61.41.41.31.41.2
Reaction time false alarm rate0.10.20.4-0.1-0.5-0.0-0.5-0.5-0.6-0.2-0.3-0.4
Reaction time premature initiation rate1.62.23.11.81.01.41.51.71.61.31.61.4
Reaction time premature initiations3.25.86.72.61.92.32.42.62.62.32.62.3
Std. dev. reaction times0.51.01.61.11.30.91.21.01.00.80.90.8
Reaction time trials completed0.91.72.21.11.21.21.31.31.51.31.41.4
Reaction time trials AUC0.71.31.70.91.01.01.11.21.31.11.31.2
Run reversals in cocaine runway, females0.30.30.6-0.2-0.8-0.5-0.7-0.6-0.6-0.6-0.6-0.6
Run reversals in cocaine runway, males1.11.11.30.71.11.11.01.11.11.11.11.1
Latency to leave start box in cocaine runway0.70.80.9-0.8-0.8-1.0-0.9-0.9-0.9-1.0-0.9-1.0
Latency to leave start box in cocaine runway, F0.50.50.7-0.6-0.7-0.8-0.7-0.7-0.7-0.8-0.7-0.8
Latency to leave start box in cocaine runway, M0.00.00.00.00.1-0.10.0-0.0-0.1-0.0-0.0-0.0
Std. dev. time between licks in bursts0.10.10.20.3-0.10.40.40.40.40.30.20.3
Total sessions with >9 infusions0.60.70.9-0.6-0.9-0.9-0.9-0.8-0.9-0.9-0.9-0.8
Short access day 1 total inactive lever presses1.62.12.8-1.7-1.5-1.5-1.4-1.4-1.4-1.4-1.5-1.4
Short access day 10 total inactive lever presses0.10.20.3-0.5-0.5-0.3-0.6-0.6-0.5-0.3-0.4-0.4
Short access day 1 total infusions2.73.64.0-1.9-1.9-1.9-1.9-1.9-2.0-1.8-1.9-1.7
Short access day 10 total infusions3.24.04.5-1.6-1.9-2.1-2.1-2.0-2.1-2.1-2.1-2.0
Short access total infusions1.92.42.7-1.3-1.6-1.6-1.6-1.5-1.6-1.6-1.6-1.5
Short access day 1 locomotion1.62.02.4-1.5-1.4-1.5-1.5-1.4-1.4-1.4-1.4-1.2
Short access day 10 total locomotion1.12.12.5-1.5-1.3-1.6-1.6-1.5-1.5-1.4-1.3-1.4
Short access total locomotion2.02.32.8-1.6-1.5-1.7-1.6-1.4-1.5-1.5-1.5-1.4
One hour access (0.3 mA shock)4.55.26.7-2.6-2.2-2.2-2.2-2.3-2.3-2.1-2.3-2.2
Compulsive drug intake1.92.33.21.81.21.71.61.51.61.51.41.3
One hour access (shock baseline)3.75.78.4-2.9-2.1-2.5-2.4-2.3-2.4-2.2-2.3-2.2
Social response proportion0.10.20.30.50.40.30.40.30.40.40.40.4
Social responses0.30.30.40.60.50.60.60.60.60.50.60.5
Social time0.40.50.80.80.70.70.90.70.80.60.70.6
Soleus weight1.95.68.7-2.9-2.3-2.2-2.5-2.4-2.5-2.1-2.1-2.1
Bone: stiffness0.10.20.80.90.70.30.50.40.30.30.30.3
Tibialis anterior weight9.833.141.96.55.95.95.55.45.35.85.65.8
Time to tail flick, vehicle, before self-admin0.10.10.2-0.1-0.2-0.3-0.4-0.4-0.4-0.3-0.3-0.0
Time to tail flick, vehicle, after self-admin0.60.81.2-0.3-0.9-0.7-1.1-0.9-1.0-0.9-0.9-0.9
Time to tail flick, test, before self-admin4.54.76.1-2.0-2.4-2.1-2.5-2.2-2.3-2.0-2.0-2.0
Time to tail flick, test, after self-admin0.10.10.20.20.30.30.30.20.20.30.30.4
Delta time to tail flick, vehicle, before/after SA0.10.10.20.1-0.4-0.2-0.4-0.2-0.3-0.3-0.3-0.5
Delta time to tail flick, test, before/after SA6.66.88.02.32.82.62.82.62.72.52.52.5
Tibia length1.74.87.32.12.72.12.32.02.22.12.12.0
Ambulatory time before self-admin0.00.00.10.10.3-0.10.00.10.1-0.1-0.0-0.1
Ambulatory time after self-admin0.50.60.7-0.8-0.5-0.8-0.8-0.8-0.8-0.7-0.7-0.8
Bone: tissue strength0.00.00.1-0.2-0.2-0.3-0.3-0.1-0.2-0.1-0.1-0.1
Total heroin consumption3.23.74.92.21.81.81.92.02.01.81.91.9
Bone: trabecular number0.20.40.6-0.1-0.4-0.7-0.5-0.6-0.6-0.8-0.7-0.8
Bone: trabecular spacing0.10.10.2-0.4-0.4-0.2-0.1-0.2-0.2-0.3-0.3-0.3
Bone: trabecular thickness1.21.51.9-1.2-1.2-1.4-1.1-1.2-1.1-1.3-1.1-1.3
Bone: trabecular tissue density0.81.12.7-1.6-0.8-0.9-1.0-1.1-1.2-0.7-1.0-0.8
Water consumed over 24 hours0.40.50.90.90.70.71.00.70.60.60.60.7
Number of responses in last shaping day0.00.00.10.1-0.10.10.30.20.10.00.10.2