LOC120099893

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL isoform ratio XR_005499351.1 0.21 0.14 5.1e-03 0 0 -0.01 -0 3.0e-01 2.4e-01 9.7e-01 4.3e-01
2 BLA gene expression LOC120099893 0.6 0.18 0.0e+00 0.42 0.46 0.44 0.44 1.5e-24 2.1e-27 4.5e-26 1.3e-25
3 Adipose gene expression LOC120099893 0.04 0.03 7.1e-05 0.03 0.03 0.02 0.03 1.1e-04 4.9e-04 9.1e-04 2.0e-04
4 PL gene expression LOC120099893 0.5 0.14 0.0e+00 0.54 0.57 0.57 0.56 1.9e-70 1.9e-76 8.7e-76 2.7e-74
5 Brain isoform ratio XR_005499352.1 0.09 0.06 2.6e-08 0.09 0.1 0.08 0.09 8.1e-09 4.1e-09 4.8e-08 1.3e-08
6 Brain isoform ratio XR_005499351.1 0.09 0.06 2.8e-08 0.09 0.09 0.08 0.09 9.5e-09 4.5e-09 5.3e-08 1.5e-08
7 IL isoform ratio XR_005499352.1 0.21 0.14 4.4e-03 0 0 -0.01 -0.01 2.7e-01 3.2e-01 6.9e-01 5.1e-01
8 BLA mRNA stability LOC120099893 0.98 0.01 0.0e+00 0.39 0.35 0.39 0.38 4.0e-22 1.1e-19 6.6e-22 1.1e-21
9 IL mRNA stability LOC120099893 0.26 0.17 3.9e-04 0.31 0.2 0.29 0.31 3.0e-08 1.3e-05 8.5e-08 4.4e-08
10 PL mRNA stability LOC120099893 0.99 0 0.0e+00 0.27 0.26 0.27 0.27 8.8e-30 1.6e-28 2.9e-29 9.0e-30
11 Brain mRNA stability LOC120099893 0.98 0 0.0e+00 0.34 0.34 0.34 0.34 1.2e-32 2.7e-32 3.4e-32 4.7e-32
12 NAcc gene expression LOC120099893 0.11 0.07 4.8e-14 0.12 0.12 0.12 0.12 1.0e-13 7.5e-14 1.2e-13 6.2e-14
13 BLA isoform ratio XR_005499352.1 0.07 0.05 1.7e-03 0.04 0.03 -0 0.03 2.5e-03 6.1e-03 3.8e-01 1.2e-02
14 BLA isoform ratio XR_005499351.1 0.07 0.05 1.9e-03 0.04 0.03 -0 0.03 3.0e-03 8.1e-03 4.3e-01 1.6e-02
15 Brain gene expression LOC120099893 0.46 0.18 0.0e+00 0.42 0.43 0.44 0.43 2.8e-42 2.3e-43 5.2e-44 8.2e-44
16 IL gene expression LOC120099893 0.69 0.16 2.0e-12 0.22 0.21 0.19 0.2 5.2e-06 7.9e-06 2.4e-05 1.4e-05
17 OFC isoform ratio XR_005499351.1 0.23 0.14 1.6e-04 0.16 0.14 0.13 0.16 1.2e-04 2.6e-04 6.2e-04 1.3e-04
18 OFC isoform ratio XR_005499352.1 0.25 0.15 9.4e-05 0.16 0.15 0.14 0.16 1.1e-04 2.0e-04 4.3e-04 1.4e-04
19 PL isoform ratio XR_005499351.1 0.13 0.1 5.9e-12 0.09 0.11 0.1 0.1 2.1e-10 6.1e-12 5.1e-11 1.6e-11
20 PL isoform ratio XR_005499352.1 0.13 0.1 6.2e-12 0.09 0.11 0.1 0.1 3.3e-10 9.8e-12 5.6e-11 2.7e-11
21 pVTA gene expression LOC120099893 0.15 0.09 3.5e-05 0.09 0.11 0.09 0.09 1.2e-04 1.8e-05 1.2e-04 7.9e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.10.10.2-0.0-0.20.2-0.3-0.30.30.50.20.20.20.2-0.30.3-0.30.30.4-0.40.40.3-0.3-0.5
Area under the delay curve0.20.20.4-0.40.5-0.60.50.4-0.4-0.6-0.5-0.5-0.5-0.50.5-0.60.6-0.3-0.40.4-0.4-0.50.50.5
BMI with tail0.10.30.3-0.30.5-0.50.50.5-0.5-0.3-0.5-0.5-0.5-0.50.5-0.50.5-0.5-0.50.5-0.5-0.60.60.6
BMI without tail0.81.73.2-0.11.2-1.41.21.1-1.2-1.3-1.4-1.4-1.4-1.41.3-1.41.4-1.2-1.11.1-1.1-1.51.51.8
Body weight0.73.15.2-0.51.6-1.91.61.6-1.6-1.6-1.8-1.8-1.8-1.81.8-1.81.8-1.8-1.71.7-1.7-2.02.02.3
Weight adjusted by age0.10.10.40.30.3-0.50.30.3-0.3-0.4-0.4-0.4-0.4-0.40.4-0.40.4-0.3-0.30.3-0.3-0.40.40.6
Bone surface0.50.81.41.2-0.90.8-0.9-0.90.91.20.80.80.80.8-0.80.9-0.90.80.9-0.90.90.8-0.8-0.7
Bone volume0.30.61.10.9-0.80.7-0.8-0.80.81.10.70.70.70.7-0.70.7-0.70.70.7-0.70.70.7-0.7-0.6
Breakpoint value in progressive ratio session0.10.10.2-0.2-0.20.3-0.2-0.20.20.30.30.30.30.3-0.20.3-0.30.20.2-0.20.20.3-0.3-0.4
Number of licking bursts5.76.88.2-2.92.7-2.62.72.7-2.7-2.4-2.7-2.7-2.7-2.72.5-2.62.6-2.6-2.52.5-2.5-2.52.52.3
Context. condit. distance diff. score3.44.26.72.1-2.11.9-2.0-2.02.02.62.12.12.12.1-1.92.0-2.02.02.0-2.02.02.0-2.0-1.8
Locomotion velocity, session 10.20.20.4-0.1-0.40.5-0.4-0.40.40.60.50.50.50.5-0.50.5-0.50.40.4-0.40.40.5-0.5-0.7
Locomotion distance, session 11.41.81.81.2-1.31.3-1.3-1.31.31.21.31.31.31.3-1.31.3-1.31.41.4-1.41.41.3-1.3-1.3
Locomotion velocity, session 20.00.00.10.2-0.10.2-0.1-0.10.1-0.10.10.10.10.1-0.20.1-0.10.10.1-0.10.10.1-0.1-0.1
Locomotion distance, session 20.50.70.90.9-0.90.8-0.9-0.90.90.60.90.90.90.9-0.90.9-0.90.90.9-0.90.90.8-0.8-0.8
Locomotion velocity, session 31.51.82.21.1-1.31.3-1.3-1.31.31.51.41.41.41.4-1.31.3-1.31.41.4-1.41.41.3-1.3-1.3
Locomotion distance, session 32.83.03.61.5-1.71.7-1.7-1.71.71.91.81.81.81.8-1.71.7-1.71.81.8-1.81.81.7-1.7-1.7
Stereotopy head waving bouts, day 30.81.01.1-0.81.0-1.01.01.0-1.0-1.0-1.0-1.0-1.0-1.01.0-0.90.9-1.0-1.01.0-1.0-1.01.01.0
Stereotopy head waving duration, day 30.20.20.30.3-0.50.4-0.5-0.50.50.40.50.50.50.5-0.40.5-0.50.40.4-0.40.40.5-0.5-0.5
Locomotion velocity, session 70.00.00.2-0.40.1-0.00.10.1-0.10.4-0.0-0.0-0.0-0.00.1-0.00.0-0.1-0.10.1-0.1-0.00.0-0.1
Locomotion distance, session 70.20.20.2-0.50.5-0.40.50.5-0.5-0.0-0.5-0.5-0.5-0.50.4-0.40.4-0.4-0.40.4-0.4-0.40.40.4
Stereotopy head waving bouts, day 73.13.53.92.0-1.91.8-1.9-1.91.91.71.91.91.91.9-1.91.9-1.91.91.9-1.91.91.8-1.8-1.7
Stereotopy head waving duration, day 72.93.64.72.2-1.91.8-1.9-1.91.91.71.91.91.91.9-1.91.9-1.91.91.9-1.91.91.8-1.8-1.6
Locomotion velocity, session 80.91.12.31.1-1.11.1-1.0-1.01.01.51.01.01.01.0-1.01.1-1.11.01.0-1.01.01.0-1.0-0.9
Locomotion distance, session 82.63.85.12.1-2.01.8-2.0-2.02.02.32.02.02.02.0-1.92.0-2.01.91.9-1.91.91.8-1.8-1.7
Degree of sensitization distance3.43.44.1-1.31.8-1.81.81.8-1.8-1.7-1.9-1.9-1.9-1.91.9-1.81.8-1.9-1.91.9-1.9-1.91.92.0
Degree of sensitization stereotypy6.47.08.32.9-2.72.6-2.7-2.72.72.42.72.72.72.7-2.62.6-2.62.72.7-2.72.72.6-2.5-2.3
Conditioned locomotion0.00.10.2-0.1-0.20.1-0.2-0.20.20.40.20.20.20.2-0.20.2-0.20.20.3-0.30.30.3-0.3-0.4
Cocaine response after cond. corrected2.93.33.4-1.81.8-1.81.81.8-1.8-1.7-1.8-1.8-1.8-1.81.8-1.81.8-1.8-1.81.8-1.8-1.81.81.7
Cocaine response after cond. not corrected0.70.70.8-0.90.9-0.90.90.9-0.9-0.8-0.9-0.9-0.9-0.90.9-0.80.8-0.9-0.90.9-0.9-0.80.80.8
Cocaine response before conditioning3.44.14.31.9-2.02.0-2.0-2.02.02.02.12.12.12.1-2.02.0-2.02.02.0-2.02.02.0-2.0-2.0
Saline control response0.50.62.21.5-0.90.8-0.9-0.90.80.80.80.80.80.8-0.80.7-0.70.70.7-0.70.70.6-0.6-0.3
Bone: connectivity density0.40.60.80.4-0.70.7-0.7-0.70.70.80.70.70.70.7-0.80.8-0.80.80.8-0.80.80.8-0.8-0.9
Bone: cortical apparent density2.83.74.0-1.92.0-2.02.02.0-2.0-1.8-2.0-2.0-2.0-2.01.9-1.91.9-1.9-1.81.8-1.8-1.91.91.8
Bone: cortical area0.00.00.40.5-0.10.0-0.1-0.10.10.60.00.00.00.0-0.00.0-0.00.00.1-0.10.1-0.00.00.2
Bone: cortical porosity2.02.22.51.3-1.51.5-1.5-1.51.51.61.61.61.61.6-1.51.5-1.51.41.4-1.41.41.5-1.5-1.5
Bone: cortical porosity1.82.02.31.2-1.41.4-1.4-1.41.41.51.51.51.51.5-1.41.4-1.41.31.3-1.31.31.4-1.4-1.4
Bone: cortical thickness0.00.10.2-0.40.3-0.20.30.3-0.30.3-0.3-0.3-0.3-0.30.2-0.30.3-0.2-0.20.2-0.2-0.20.20.1
Bone: cortical thickness0.40.41.20.5-0.60.6-0.6-0.60.61.10.60.60.60.6-0.60.6-0.60.60.7-0.70.70.6-0.6-0.6
Bone: cortical tissue density2.63.53.8-1.91.9-1.91.91.9-1.9-1.7-1.9-1.9-1.9-1.91.9-1.91.9-1.8-1.81.8-1.8-1.91.91.7
Condit. Reinf. active minus inactive responses0.10.10.30.10.2-0.30.20.2-0.2-0.4-0.3-0.3-0.3-0.30.3-0.30.3-0.3-0.30.3-0.3-0.40.40.5
Condit. Reinf. active-inactive response ratio0.00.00.20.40.1-0.20.10.1-0.1-0.1-0.2-0.2-0.2-0.20.2-0.20.2-0.2-0.20.2-0.2-0.20.20.5
Condit. Reinf. active responses0.10.10.3-0.10.3-0.40.30.3-0.3-0.5-0.3-0.3-0.3-0.30.3-0.40.4-0.3-0.30.3-0.3-0.40.40.4
Condit. Reinf. inactive responses0.00.00.1-0.20.00.00.00.0-0.0-0.30.00.00.00.0-0.0-0.00.00.00.0-0.00.00.0-0.0-0.1
Incentive salience index mean0.00.00.10.30.1-0.20.10.1-0.1-0.4-0.2-0.2-0.2-0.20.1-0.20.2-0.1-0.10.1-0.1-0.20.20.3
Condit. Reinf. lever presses0.00.00.10.3-0.10.0-0.1-0.10.1-0.20.00.00.00.0-0.1-0.00.00.10.1-0.10.10.0-0.00.0
Condit. Reinf. active minus inactive responses2.12.68.12.8-1.81.5-1.8-1.81.71.41.61.61.61.6-1.51.6-1.61.61.6-1.61.61.3-1.3-0.8
Condit. Reinf. active-inactive response ratio0.91.02.01.4-1.10.9-1.0-1.01.00.91.01.01.01.0-0.91.0-1.00.90.9-0.90.90.9-0.9-0.7
Condit. Reinf. active responses2.12.910.63.3-1.91.6-1.9-1.91.81.41.61.61.61.6-1.61.6-1.61.61.6-1.61.61.3-1.3-0.7
Condit. Reinf. inactive responses0.81.04.82.2-1.10.9-1.1-1.11.10.70.90.90.90.9-0.90.9-0.90.91.0-1.01.00.7-0.7-0.2
Condit. Reinf. lever presses8.811.925.25.0-3.73.5-3.6-3.63.63.23.43.43.43.4-3.53.4-3.43.43.3-3.33.33.1-3.1-2.3
Condit. Reinf. lever reinforcers received3.04.212.93.6-2.21.9-2.2-2.22.21.72.02.02.02.0-2.01.9-1.92.02.0-2.02.01.7-1.7-1.0
Conditioned reinforcement - actives4.04.04.32.1-2.02.0-2.0-2.12.12.02.02.02.02.0-1.92.0-2.02.11.9-1.91.91.9-1.9-1.8
Conditioned reinforcement - inactives0.30.30.6-0.40.5-0.60.50.5-0.5-0.5-0.5-0.5-0.5-0.50.7-0.50.5-0.7-0.80.8-0.8-0.50.50.5
Conditioned locomotion4.95.86.62.2-2.42.6-2.4-2.42.42.42.52.52.52.5-2.52.4-2.42.62.4-2.42.42.4-2.4-2.3
Patch foraging indifference point 0 sec2.94.77.52.7-2.32.0-2.2-2.32.32.12.22.22.22.2-2.12.2-2.22.22.2-2.22.22.0-2.0-1.7
Patch foraging indifference point AUC0.60.71.2-0.30.8-0.80.80.8-0.8-1.1-0.9-0.9-0.9-0.90.7-0.90.9-0.9-0.70.7-0.7-0.90.91.0
Delay disc. indifference point, 0s delay0.20.20.70.8-0.50.2-0.5-0.50.50.50.50.50.50.5-0.40.5-0.50.50.6-0.60.60.4-0.4-0.2
Delay disc. indifference point, 16s delay0.00.00.0-0.20.0-0.10.10.0-0.0-0.1-0.0-0.0-0.0-0.00.0-0.10.10.10.1-0.10.1-0.00.0-0.1
Delay disc. indifference point, 2s delay0.00.00.20.50.00.00.10.0-0.0-0.3-0.2-0.2-0.2-0.20.0-0.30.3-0.0-0.10.1-0.1-0.20.20.4
Delay disc. indifference point, 24s delay0.60.61.1-1.10.8-0.70.80.8-0.7-0.9-0.7-0.7-0.7-0.70.7-0.90.9-0.6-0.60.6-0.6-0.70.70.5
Delay disc. indifference point, 4s delay0.10.20.40.40.3-0.60.30.2-0.2-0.5-0.4-0.4-0.4-0.40.5-0.50.5-0.2-0.20.2-0.2-0.50.50.7
Delay disc. indifference point, 8s delay0.00.00.1-0.00.1-0.30.10.0-0.00.0-0.1-0.1-0.1-0.10.20.0-0.00.00.0-0.00.0-0.10.10.1
Indifference point function ln k3.24.45.11.7-2.02.1-2.0-2.12.12.22.12.12.12.1-2.12.1-2.12.32.2-2.22.22.1-2.1-2.1
Indifference point function log k3.24.45.11.7-2.02.1-2.0-2.12.12.22.12.12.12.1-2.12.1-2.12.32.2-2.22.22.1-2.1-2.1
Patch foraging total patch changes 0 sec2.23.55.82.4-1.91.8-1.9-2.01.91.71.91.91.91.9-1.81.9-1.91.91.8-1.81.81.7-1.7-1.4
Patch foraging total patch changes 12 sec0.00.10.60.8-0.10.0-0.1-0.10.1-0.3-0.0-0.0-0.0-0.0-0.1-0.10.1-0.00.1-0.10.1-0.20.20.4
Patch foraging total patch changes 18 sec0.70.92.51.6-1.11.0-1.0-1.01.00.81.01.01.01.0-0.91.0-1.00.70.9-0.90.90.8-0.8-0.6
Patch foraging total patch changes 24 sec0.00.00.60.8-0.2-0.0-0.1-0.10.1-0.30.00.00.00.00.0-0.00.0-0.1-0.00.0-0.0-0.10.10.4
Patch foraging total patch changes 6 sec0.50.71.11.0-0.80.8-0.8-0.80.80.60.80.80.80.8-0.90.7-0.70.91.0-1.01.00.7-0.7-0.6
Patch foraging time to switch 0 sec1.72.65.6-2.41.7-1.51.71.7-1.7-1.6-1.6-1.6-1.6-1.61.6-1.51.5-1.7-1.61.6-1.6-1.41.41.1
Patch foraging water rate 0 sec2.54.06.02.4-2.02.0-2.0-2.12.02.02.02.02.02.0-2.01.9-1.92.12.0-2.02.01.8-1.8-1.6
Patch foraging water rate 12 sec2.53.94.62.1-2.12.0-2.0-2.02.02.02.02.02.02.0-1.92.0-2.01.91.9-1.91.91.9-1.9-1.7
Patch foraging water rate 18 sec0.60.71.81.3-1.00.8-0.9-0.90.90.90.80.80.80.8-0.80.8-0.80.90.8-0.80.80.8-0.8-0.5
Patch foraging water rate 24 sec2.53.54.31.6-1.81.8-1.8-1.81.81.91.91.91.91.9-1.91.8-1.81.92.1-2.12.11.9-1.9-1.8
Patch foraging water rate 6 sec1.72.42.81.6-1.61.7-1.6-1.61.61.61.61.61.61.6-1.61.6-1.61.51.5-1.51.51.6-1.6-1.4
Seeking ratio, delayed vs. immediate footshock0.20.20.9-0.90.3-0.30.30.4-0.4-0.4-0.2-0.2-0.2-0.20.4-0.20.2-0.6-0.70.7-0.7-0.10.1-0.1
Distance traveled before self-admin1.41.52.0-1.41.4-1.21.31.3-1.3-1.3-1.4-1.4-1.4-1.41.1-1.31.3-0.9-0.90.9-0.9-1.31.31.1
Distance traveled after self-admin0.40.40.8-0.1-0.50.8-0.5-0.50.50.60.60.60.60.6-0.70.6-0.60.60.6-0.60.60.7-0.7-0.9
Extensor digitorum longus weight0.52.12.8-0.91.4-1.41.41.4-1.4-1.3-1.5-1.5-1.5-1.51.4-1.61.6-1.4-1.41.4-1.4-1.61.61.7
Bone: elastic displacement0.50.52.1-1.40.8-0.70.80.8-0.8-0.6-0.7-0.7-0.7-0.70.7-0.60.6-0.7-0.70.7-0.7-0.60.60.2
Bone: elastic work0.20.21.7-1.30.6-0.40.50.5-0.5-0.1-0.4-0.4-0.4-0.40.4-0.40.4-0.5-0.40.4-0.4-0.30.3-0.1
Bone: endosteal estimation0.00.11.31.1-0.30.1-0.2-0.20.20.20.00.00.00.0-0.10.1-0.10.10.0-0.00.0-0.10.10.4
Bone: endosteal perimeter0.10.32.11.5-0.60.4-0.6-0.60.60.50.40.40.40.4-0.40.4-0.40.40.4-0.40.40.3-0.30.1
Epididymis fat weight2.04.65.6-1.52.1-2.42.12.1-2.1-2.0-2.2-2.2-2.2-2.22.3-2.22.2-2.1-2.22.2-2.2-2.32.32.3
Delta time in closed arm before/after self-admin6.15.96.7-1.82.4-2.52.42.4-2.4-2.4-2.4-2.4-2.4-2.42.5-2.42.4-2.4-2.42.4-2.4-2.52.52.6
Delta time in open arm before/after self-admin2.62.64.42.1-1.71.7-1.7-1.71.71.61.61.61.61.6-1.61.6-1.61.41.4-1.41.41.5-1.5-1.2
Diff in mean of infusions in LGA sessions3.43.84.8-2.22.0-1.92.02.0-2.0-1.9-2.0-2.0-2.0-2.02.0-1.91.9-2.0-2.02.0-2.0-1.81.81.6
Delay discount exponential model param0.30.30.50.4-0.50.7-0.5-0.50.50.70.50.50.50.5-0.60.7-0.70.40.4-0.40.40.6-0.6-0.5
Extinction: sum of active levers before priming0.10.10.2-0.30.3-0.30.30.3-0.3-0.3-0.3-0.3-0.3-0.30.4-0.30.3-0.4-0.40.4-0.4-0.30.30.3
Active lever presses in extinction session 66.36.17.22.0-2.32.5-2.4-2.42.42.52.42.42.42.4-2.62.5-2.52.72.7-2.72.72.4-2.4-2.5
Bone: final force0.00.00.0-0.20.2-0.20.20.2-0.20.1-0.2-0.2-0.2-0.20.2-0.20.2-0.2-0.20.2-0.2-0.20.20.2
Bone: final moment0.00.00.10.10.0-0.00.00.0-0.00.3-0.0-0.0-0.0-0.00.0-0.00.0-0.1-0.00.0-0.0-0.10.10.1
Food consumed during 24 hour testing period4.45.46.32.5-2.42.3-2.4-2.42.42.42.32.32.32.3-2.32.3-2.32.32.3-2.32.32.2-2.2-2.0
Glucose0.10.20.40.2-0.30.5-0.4-0.40.40.60.40.40.40.4-0.50.4-0.40.40.4-0.40.40.4-0.4-0.4
Heart weight1.11.52.21.5-1.31.4-1.3-1.31.31.01.31.31.31.3-1.31.2-1.21.31.2-1.21.21.1-1.1-1.0
Delay discount hyperbolic model param0.30.30.50.3-0.50.7-0.5-0.50.50.70.50.50.50.5-0.60.7-0.70.40.4-0.40.40.6-0.6-0.6
Intermittent access intake day 1-15 change0.70.71.10.9-0.81.0-0.8-0.80.80.70.70.70.70.7-1.00.7-0.70.91.0-1.01.00.7-0.7-0.7
Intermittent access intake escalation0.90.91.51.0-0.91.1-0.9-0.90.90.80.80.80.80.8-1.10.8-0.81.11.2-1.21.20.8-0.8-0.8
Intermittent access intake escalation 20.00.00.10.20.2-0.30.10.1-0.1-0.2-0.2-0.2-0.2-0.20.0-0.20.20.20.3-0.30.3-0.20.20.3
Intermitt. access day 1 inactive lever presses0.60.71.2-0.70.7-0.80.70.8-0.8-0.8-0.8-0.8-0.8-0.80.9-0.80.8-0.9-1.11.1-1.1-0.70.70.7
Intermitt. access day 15 inactive lever presses0.50.51.20.6-0.81.1-0.8-0.70.70.70.80.80.80.8-0.80.8-0.80.50.4-0.40.40.8-0.8-0.8
Intermitt. access escalation Index0.20.20.40.6-0.40.1-0.5-0.50.50.40.40.40.40.4-0.30.4-0.40.50.6-0.60.60.4-0.4-0.3
Intermittent access day 1 total infusions0.81.01.81.4-1.21.2-1.1-1.01.01.01.11.11.11.1-0.91.1-1.10.60.5-0.50.51.0-1.0-0.8
Intermittent access day 15 total infusions1.92.12.81.7-1.51.6-1.5-1.51.51.41.51.51.51.5-1.51.4-1.41.31.3-1.31.31.4-1.4-1.2
Intermittent access terminal intake (last 3 days)1.21.32.11.5-1.21.2-1.2-1.21.21.11.11.11.11.1-1.11.1-1.11.11.0-1.01.01.1-1.1-0.9
Intermittent access total infusions0.80.91.71.3-1.11.2-1.1-1.01.01.01.01.01.01.0-0.91.0-1.00.70.6-0.60.61.0-1.0-0.8
Intermittent access day 1 locomotion0.40.40.80.5-0.70.9-0.7-0.70.70.70.80.80.80.8-0.70.7-0.70.40.4-0.40.40.7-0.7-0.7
Intermittent access day 15 total locomotion1.82.03.01.5-1.41.7-1.4-1.41.41.41.41.41.41.4-1.61.4-1.41.41.4-1.41.41.3-1.3-1.2
Intermittent access total locomotion0.80.91.81.1-1.01.4-1.0-1.01.01.01.01.01.01.0-1.11.0-1.00.70.7-0.70.70.9-0.9-0.8
Intermittent access standard deviation0.00.00.10.10.2-0.10.10.1-0.1-0.2-0.2-0.2-0.2-0.20.1-0.20.2-0.1-0.10.1-0.1-0.20.20.3
Left kidney weight0.10.41.30.70.4-0.70.40.4-0.4-0.7-0.6-0.6-0.6-0.60.6-0.60.6-0.4-0.40.4-0.4-0.80.81.2
Right kidney weight0.10.41.10.40.5-0.60.50.4-0.5-0.7-0.6-0.6-0.6-0.60.5-0.60.6-0.3-0.40.4-0.4-0.80.81.1
Cocaine induced anxiety1.41.63.0-1.71.4-1.21.41.3-1.3-1.3-1.3-1.3-1.3-1.31.2-1.31.3-1.2-1.21.2-1.2-1.21.21.0
Post-drug Anxiety1.41.61.7-1.31.3-1.11.31.3-1.3-1.3-1.3-1.3-1.3-1.31.1-1.31.3-1.2-1.21.2-1.2-1.21.21.2
Baseline Anxiety0.30.31.11.1-0.70.5-0.7-0.60.60.50.50.50.50.5-0.50.5-0.50.50.5-0.50.50.5-0.5-0.3
Tail length0.82.36.10.71.2-1.61.21.2-1.2-1.7-1.6-1.6-1.6-1.61.5-1.51.5-1.5-1.31.3-1.3-1.81.82.5
Length with tail0.93.16.3-0.01.5-1.81.51.6-1.6-1.9-1.8-1.8-1.8-1.81.8-1.81.8-1.9-1.81.8-1.8-2.02.02.5
Length without tail0.10.20.4-0.60.4-0.30.40.5-0.4-0.4-0.3-0.3-0.3-0.30.4-0.40.4-0.6-0.60.6-0.6-0.40.40.3
Times rat made contact with spout1.21.41.6-0.91.2-1.11.21.1-1.2-1.1-1.2-1.2-1.2-1.21.1-1.21.2-1.1-1.11.1-1.1-1.21.21.3
Lifetime Intake1.21.32.31.5-1.41.4-1.3-1.21.21.21.21.21.21.2-1.11.2-1.20.90.7-0.70.71.2-1.2-1.0
Liver weight, left2.23.54.1-1.41.8-1.91.81.8-1.8-2.0-1.9-1.9-1.9-1.91.9-1.81.8-1.9-1.91.9-1.9-1.91.92.0
Liver weight, right4.98.29.2-2.12.8-3.02.82.8-2.8-3.0-2.9-2.9-2.9-2.93.0-2.92.9-2.9-2.92.9-2.9-2.92.93.0
Locomotor activity0.50.81.51.0-0.80.7-0.9-0.90.90.70.90.90.90.9-0.90.8-0.81.21.2-1.21.20.8-0.8-0.7
Locomotor testing distance0.81.33.01.7-1.21.0-1.2-1.21.20.81.11.11.11.1-1.11.0-1.01.31.3-1.31.30.9-0.9-0.7
Locomotor testing rearing0.10.10.40.50.2-0.40.20.2-0.2-0.5-0.3-0.3-0.3-0.30.3-0.30.3-0.2-0.10.1-0.1-0.40.40.6
Locomotion in novel chamber2.02.44.11.1-1.31.5-1.3-1.41.41.51.51.51.51.5-1.71.5-1.52.02.0-2.02.01.4-1.4-1.5
Locomotion in novel chamber post-restriction3.34.04.42.0-2.01.9-2.0-2.02.02.12.12.12.12.1-1.92.1-2.12.02.0-2.02.01.9-1.9-1.8
Fecal boli incidents, locomotor time 11.82.02.41.2-1.41.0-1.4-1.41.41.51.41.41.41.4-1.21.5-1.51.51.5-1.51.51.4-1.4-1.4
Change in fecal boli incidents, locomotor task1.11.11.3-1.11.0-0.61.11.1-1.1-1.0-1.1-1.1-1.1-1.10.8-1.11.1-1.1-1.11.1-1.1-1.01.00.9
Time >=10cm from walls, locomotor time 12.72.73.11.7-1.71.4-1.7-1.71.71.81.71.71.71.7-1.51.7-1.71.71.7-1.71.71.6-1.6-1.5
Bouts of movement, locomotor time 10.30.30.40.5-0.50.0-0.6-0.60.60.50.60.60.60.6-0.30.5-0.50.70.7-0.70.70.6-0.6-0.5
Total resting periods, locomotor time 10.60.60.80.5-0.80.3-0.8-0.80.80.70.90.90.90.9-0.60.8-0.80.90.9-0.90.90.9-0.9-0.9
Rest time, locomotor task time 10.30.30.80.1-0.50.5-0.5-0.50.50.90.60.60.60.6-0.40.7-0.70.40.4-0.40.40.6-0.6-0.7
Distance moved, locomotor task time 10.60.61.1-0.20.8-0.80.70.7-0.7-1.0-0.9-0.9-0.9-0.90.7-0.90.9-0.6-0.60.6-0.6-0.90.91.0
Vertical activity count, locomotor time 10.10.10.30.20.2-0.40.20.2-0.2-0.5-0.3-0.3-0.3-0.30.4-0.20.2-0.3-0.30.3-0.3-0.40.40.5
Time >=10cm from walls, locomotor time 20.90.91.81.3-1.10.9-1.0-1.01.01.11.01.01.01.0-0.91.0-1.00.80.8-0.80.80.9-0.9-0.7
Bouts of movement, locomotor time 20.40.41.40.00.6-1.20.50.5-0.5-0.8-0.6-0.6-0.6-0.60.9-0.70.7-0.4-0.40.4-0.4-0.70.70.9
Total resting periods, locomotor time 20.60.71.8-0.30.8-1.30.70.7-0.7-1.0-0.8-0.8-0.8-0.81.0-0.90.9-0.7-0.70.7-0.7-0.80.81.0
Rest time, locomotor task time 21.61.93.8-1.91.3-1.41.41.4-1.4-1.2-1.3-1.3-1.3-1.31.5-1.21.2-1.6-1.61.6-1.6-1.11.10.9
Distance moved, locomotor task time 21.11.33.51.9-1.21.0-1.2-1.21.21.01.11.11.11.1-1.11.0-1.01.21.2-1.21.20.9-0.9-0.6
Vertical activity count, locomotor time 20.10.10.80.9-0.30.2-0.3-0.30.30.20.20.20.20.2-0.20.2-0.20.20.2-0.20.20.1-0.10.2
Light reinforcement 12.03.65.7-2.42.0-2.01.91.9-1.9-2.3-1.8-1.8-1.8-1.81.9-1.81.8-2.0-1.81.8-1.8-1.71.71.4
Light reinforcement 20.00.00.2-0.40.00.10.00.00.0-0.20.10.10.10.1-0.10.1-0.1-0.00.0-0.00.00.1-0.1-0.3
Bone: marrow area0.00.10.90.9-0.1-0.0-0.1-0.10.10.0-0.1-0.1-0.1-0.10.1-0.00.0-0.1-0.10.1-0.1-0.20.20.6
Bone: maximum diameter0.30.62.41.5-0.80.7-0.8-0.80.81.00.60.60.60.6-0.70.7-0.70.60.7-0.70.70.5-0.5-0.2
Bone: maximum force0.00.00.30.1-0.10.0-0.0-0.00.00.50.00.00.00.0-0.00.0-0.00.00.0-0.00.00.0-0.00.0
Bone: maximum moment0.00.10.40.4-0.20.2-0.2-0.20.20.70.20.20.20.2-0.20.2-0.20.20.2-0.20.20.2-0.2-0.1
Mean time between licks in bursts0.20.33.71.9-0.60.3-0.6-0.60.50.40.30.30.30.3-0.30.3-0.30.30.3-0.30.30.1-0.10.5
Mean num. licks in bursts4.14.96.52.6-2.32.2-2.3-2.32.32.12.32.32.32.3-2.22.2-2.22.22.2-2.22.22.1-2.1-1.9
Cd content in liver1.41.52.2-1.01.2-1.01.21.2-1.2-1.5-1.3-1.3-1.3-1.31.1-1.31.3-1.2-1.21.2-1.2-1.31.31.3
Co content in liver0.10.11.11.0-0.40.4-0.4-0.40.40.30.30.30.30.3-0.40.3-0.30.20.3-0.30.30.2-0.20.1
Cu content in liver0.00.10.30.60.00.00.10.1-0.1-0.2-0.2-0.2-0.2-0.20.1-0.20.2-0.1-0.20.2-0.2-0.30.30.5
Fe content in liver0.10.10.1-0.20.3-0.30.30.3-0.3-0.2-0.3-0.3-0.3-0.30.3-0.30.3-0.4-0.30.3-0.3-0.30.30.3
K content in liver0.60.60.7-0.60.7-0.70.80.8-0.8-0.8-0.8-0.8-0.8-0.80.7-0.80.8-0.8-0.80.8-0.8-0.80.80.8
Mg content in liver0.00.00.10.3-0.20.2-0.2-0.20.20.10.10.10.10.1-0.10.1-0.10.10.1-0.10.10.1-0.1-0.0
Mn content in liver0.10.10.9-0.90.2-0.20.20.2-0.2-0.1-0.1-0.1-0.1-0.10.2-0.10.1-0.1-0.10.1-0.10.0-0.0-0.3
Na content in liver0.40.40.60.6-0.70.5-0.7-0.60.60.80.60.60.60.6-0.60.7-0.70.60.6-0.60.60.6-0.6-0.6
Rb content in liver0.30.30.91.0-0.60.8-0.6-0.60.60.30.60.60.60.6-0.70.5-0.50.50.6-0.60.60.5-0.5-0.3
Se content in liver1.51.84.2-2.11.5-1.11.41.4-1.4-1.2-1.4-1.4-1.4-1.41.2-1.31.3-1.4-1.41.4-1.4-1.21.20.9
Sr content in liver0.30.30.80.2-0.50.5-0.5-0.50.50.90.50.50.50.5-0.50.6-0.60.40.5-0.50.50.6-0.6-0.7
Zn content in liver2.93.26.02.4-1.91.9-1.9-1.91.91.71.81.81.81.8-1.81.7-1.71.81.7-1.71.71.6-1.6-1.3
Bone: minimum diameter0.51.02.00.00.9-1.00.90.9-0.9-0.7-1.1-1.1-1.1-1.11.0-1.01.0-1.0-1.01.0-1.0-1.11.11.4
Time in familiar zone, hab. session 10.20.20.2-0.20.4-0.40.40.4-0.4-0.4-0.4-0.4-0.4-0.40.4-0.50.5-0.4-0.40.4-0.4-0.40.40.5
Time in novel zone, hab. session 10.20.20.3-0.60.5-0.50.50.5-0.5-0.3-0.5-0.5-0.5-0.50.4-0.40.4-0.4-0.40.4-0.4-0.40.40.4
Total zone transitions, hab. session 10.40.50.80.3-0.70.7-0.7-0.70.70.80.70.70.70.7-0.70.8-0.80.70.7-0.70.70.8-0.8-0.9
Total locomotion distance, hab. session 12.43.44.1-1.41.8-1.91.81.8-1.8-2.0-1.9-1.9-1.9-1.91.9-1.81.8-1.8-1.81.8-1.8-1.91.91.9
Locomotion velocity, hab. session 11.41.92.7-1.01.4-1.51.41.4-1.4-1.6-1.4-1.4-1.4-1.41.4-1.31.3-1.4-1.41.4-1.4-1.41.41.5
Time in familiar zone, hab. session 20.60.61.61.3-0.90.9-0.8-0.80.80.60.80.80.80.8-0.80.7-0.70.70.7-0.70.70.7-0.7-0.4
Time in novel zone, hab. session 20.00.00.3-0.50.2-0.20.20.2-0.2-0.0-0.1-0.1-0.1-0.10.2-0.10.1-0.1-0.10.1-0.1-0.10.1-0.1
Total zone transitions, hab. session 22.32.93.11.6-1.71.7-1.7-1.71.71.61.81.81.81.8-1.71.8-1.81.71.7-1.71.71.7-1.7-1.6
Total locomotion distance, hab. session 20.81.11.7-0.41.0-1.11.01.0-1.0-1.3-1.1-1.1-1.1-1.11.1-1.01.0-1.1-1.11.1-1.1-1.11.11.3
Locomotion velocity, hab. session 21.31.72.5-0.61.2-1.31.21.2-1.2-1.6-1.3-1.3-1.3-1.31.3-1.21.2-1.3-1.31.3-1.3-1.41.41.6
Novel to familiar place preference ratio0.10.10.30.3-0.30.1-0.3-0.30.30.50.30.30.30.3-0.20.3-0.30.30.3-0.30.30.3-0.3-0.3
Novelty place preference0.10.10.30.3-0.30.2-0.3-0.30.30.60.30.30.30.3-0.20.3-0.30.30.3-0.30.30.3-0.3-0.3
Time in novel zone, NPP test0.20.30.60.5-0.50.4-0.5-0.50.50.80.50.50.50.5-0.40.5-0.50.50.5-0.50.50.5-0.5-0.4
Total zone transitions, NPP test0.60.80.90.7-0.90.9-0.9-0.90.90.90.90.90.90.9-0.90.9-0.91.01.0-1.01.00.9-0.9-1.0
Total locomotion distance, NPP test1.52.12.4-1.01.4-1.51.41.4-1.4-1.5-1.5-1.5-1.5-1.51.5-1.51.5-1.4-1.41.4-1.4-1.51.51.6
Locomotion velocity, NPP test2.02.83.0-1.31.7-1.71.71.6-1.7-1.7-1.7-1.7-1.7-1.71.7-1.71.7-1.7-1.71.7-1.7-1.71.71.7
Intraocular pressure0.71.01.30.7-0.91.1-0.9-1.01.00.91.01.01.01.0-1.11.0-1.01.01.1-1.11.11.0-1.0-1.0
Delta distance traveled before/after self-admin2.73.03.61.6-1.91.9-1.8-1.71.71.81.81.81.81.8-1.71.8-1.81.41.4-1.41.41.8-1.8-1.7
Delta ambulatory time before/after self-admin3.53.84.51.7-2.12.1-2.0-2.02.02.02.02.02.02.0-1.92.0-2.01.71.6-1.61.62.1-2.1-2.0
Parametrial fat weight2.14.04.8-1.72.0-1.82.02.0-2.0-2.1-2.0-2.0-2.0-2.02.0-2.02.0-2.2-2.22.2-2.2-2.02.02.0
Pavlov. Cond. lever latency0.60.81.7-1.30.9-0.80.90.9-0.9-0.8-0.9-0.9-0.9-0.90.8-0.80.8-0.9-0.90.9-0.9-0.80.80.6
Pavlov. Cond. magazine entry latency1.31.73.92.0-1.41.2-1.4-1.41.41.21.31.31.31.3-1.21.2-1.21.31.3-1.31.31.1-1.1-0.8
Pavlov. Cond. change in total contacts0.60.71.61.3-0.90.8-0.9-0.90.90.70.80.80.80.8-0.80.7-0.70.80.8-0.80.80.7-0.7-0.5
Pavlov. Cond. index score1.21.53.81.9-1.31.1-1.3-1.31.31.01.21.21.21.2-1.21.1-1.11.21.2-1.21.21.1-1.1-0.7
Pavlov. Cond. latency score1.31.63.71.9-1.41.2-1.3-1.31.31.11.31.31.31.3-1.21.2-1.21.21.2-1.21.21.1-1.1-0.8
Pavlov. Cond. lever contacts0.30.41.31.1-0.70.5-0.6-0.70.60.50.60.60.60.6-0.60.5-0.50.60.6-0.60.60.5-0.5-0.2
Pavlov. Cond. magazine entry number2.02.44.8-2.21.7-1.51.61.7-1.6-1.5-1.6-1.6-1.6-1.61.5-1.51.5-1.5-1.51.5-1.5-1.41.41.1
Pavlov. Cond. intertrial magazine entries0.40.51.2-1.10.8-0.70.70.7-0.7-0.9-0.7-0.7-0.7-0.70.7-0.70.7-0.7-0.70.7-0.7-0.60.60.4
Pavlov. Cond. lever-magazine prob. diff.1.01.33.01.7-1.21.1-1.2-1.21.20.91.11.11.11.1-1.11.0-1.01.11.1-1.11.11.0-1.0-0.7
Pavlov. Cond. response bias0.40.41.41.2-0.70.6-0.7-0.70.70.60.60.60.60.6-0.60.6-0.60.60.6-0.60.60.5-0.5-0.3
Pavlov. Cond. lever latency10.113.626.4-5.13.9-3.73.93.9-3.8-3.7-3.6-3.6-3.6-3.63.7-3.63.6-3.6-3.63.6-3.6-3.33.32.6
Pavlov. Cond. magazine entry latency3.94.56.22.5-2.22.2-2.2-2.22.22.12.12.12.12.1-2.22.1-2.12.12.1-2.12.12.0-2.0-1.8
Pavlov. Cond. change in total contacts9.212.621.94.7-3.73.6-3.7-3.73.73.53.53.53.53.5-3.53.5-3.53.53.5-3.53.53.3-3.2-2.6
Pavlov. Cond. index score8.711.220.34.5-3.53.4-3.5-3.53.53.33.33.33.33.3-3.33.3-3.33.33.3-3.33.33.0-3.0-2.4
Pavlov. Cond. latency score8.110.117.94.2-3.43.2-3.3-3.33.33.23.13.13.13.1-3.23.1-3.13.13.1-3.13.12.9-2.9-2.3
Pavlov. Cond. lever contacts10.614.527.95.3-4.03.9-4.0-4.03.93.73.73.73.73.7-3.83.7-3.73.73.7-3.73.73.4-3.4-2.7
Pavlov. Cond. magazine entry number6.78.211.6-3.43.0-3.03.03.0-2.9-2.8-2.9-2.9-2.9-2.92.9-2.92.9-2.8-2.82.8-2.8-2.72.72.4
Pavlov. Cond. intertrial magazine entries0.91.21.8-0.41.0-1.11.01.0-1.0-1.1-1.1-1.1-1.1-1.11.1-1.11.1-1.1-1.11.1-1.1-1.21.21.3
Pavlov. Cond. lever-magazine prob. diff.7.79.818.64.3-3.33.2-3.3-3.33.23.13.13.13.13.1-3.13.1-3.13.13.0-3.03.02.8-2.8-2.2
Pavlov. Cond. response bias11.615.828.85.4-4.24.1-4.1-4.24.13.93.93.93.93.9-4.03.9-3.93.93.9-3.93.93.6-3.6-2.9
Time in closed arm before self-admin6.57.37.72.1-2.72.8-2.6-2.62.72.72.82.82.82.8-2.82.7-2.72.82.8-2.82.82.7-2.7-2.8
Time in closed arm after self-admin0.00.00.3-0.60.1-0.00.10.0-0.00.10.10.10.10.1-0.00.1-0.10.10.1-0.10.10.1-0.1-0.3
Time in open arm before self-admin5.76.27.3-2.72.7-2.62.62.5-2.5-2.5-2.6-2.6-2.6-2.62.4-2.52.5-2.3-2.22.2-2.2-2.52.52.2
Time in open arm after self-admin0.40.50.9-0.00.6-0.60.60.6-0.6-0.7-0.8-0.8-0.8-0.80.6-0.70.7-0.6-0.60.6-0.6-0.80.81.0
Bone: periosteal estimation0.00.11.21.1-0.30.2-0.3-0.30.30.60.10.10.10.1-0.20.2-0.20.10.1-0.10.10.0-0.00.3
Bone: periosteal perimeter0.10.21.51.2-0.60.4-0.5-0.50.50.70.40.40.40.4-0.40.4-0.40.40.4-0.40.40.3-0.30.0
Bone: post-yield work0.10.20.40.5-0.40.4-0.4-0.40.40.60.40.40.40.4-0.40.4-0.40.40.4-0.40.40.4-0.4-0.3
Progressive ratio test 1 active lever presses0.00.00.2-0.20.00.10.10.1-0.1-0.1-0.1-0.1-0.1-0.10.1-0.10.1-0.4-0.40.4-0.4-0.00.00.0
Progressive ratio test 1 breakpoint0.10.10.3-0.20.2-0.00.20.3-0.3-0.2-0.2-0.2-0.2-0.20.2-0.20.2-0.5-0.50.5-0.5-0.20.20.2
Progressive ratio test 1 inactive lever presses0.20.30.60.7-0.70.7-0.6-0.50.50.50.60.60.60.6-0.30.6-0.6-0.1-0.30.3-0.30.5-0.5-0.4
Progressive ratio test 2 active lever presses0.30.30.90.9-0.60.8-0.5-0.60.60.50.50.50.50.5-0.60.5-0.50.50.4-0.40.40.4-0.4-0.2
Progressive ratio test 2 breakpoint0.20.30.90.9-0.50.8-0.5-0.60.60.40.50.50.50.5-0.60.5-0.50.50.4-0.40.40.4-0.4-0.2
Progressive ratio test 2 inactive lever presses1.31.52.51.3-1.31.6-1.3-1.31.31.31.31.31.31.3-1.21.3-1.30.90.8-0.80.81.2-1.2-1.2
Incentive Sensitization - Responses0.50.51.81.3-0.71.0-0.7-0.80.80.50.60.60.60.6-0.90.6-0.60.90.8-0.80.80.5-0.5-0.2
Incentive Sensitization - Breakpoint0.70.71.81.3-0.81.0-0.8-0.90.80.60.70.70.70.7-1.00.7-0.71.00.9-0.90.90.6-0.6-0.4
Sum of active levers in priming session hrs 5-60.00.00.1-0.20.00.1-0.0-0.10.10.10.00.00.00.0-0.20.1-0.10.30.3-0.30.30.1-0.1-0.2
Progressive ratio0.20.30.40.3-0.40.4-0.5-0.50.50.50.50.50.50.5-0.50.6-0.60.60.5-0.50.50.5-0.5-0.6
Food seeking constrained by brief footshock0.00.00.40.60.0-0.1-0.0-0.00.0-0.1-0.1-0.1-0.1-0.10.0-0.20.20.20.1-0.10.1-0.20.20.4
Seeking ratio, punishment vs. effort0.30.30.80.30.4-0.50.40.4-0.4-0.5-0.6-0.6-0.6-0.60.5-0.70.7-0.5-0.50.5-0.5-0.70.70.9
Retroperitoneal fat weight8.628.430.4-4.15.2-5.45.25.2-5.2-5.2-5.4-5.4-5.4-5.45.4-5.35.3-5.4-5.55.5-5.5-5.45.45.5
Reaction time number correct1.11.62.20.6-1.11.3-1.1-1.11.21.51.11.11.11.1-1.31.2-1.21.51.5-1.51.51.3-1.3-1.4
Reaction time mean minus median0.10.10.70.8-0.40.3-0.4-0.40.4-0.00.40.40.40.4-0.40.3-0.30.30.4-0.40.40.3-0.3-0.1
Reaction time mean minus median AUC0.81.11.61.3-1.11.0-1.1-1.11.10.81.11.11.11.1-1.01.0-1.00.91.1-1.11.11.0-1.0-0.8
Reaction time num false alarms2.73.64.0-2.02.0-2.02.01.9-1.9-1.9-2.0-2.0-2.0-2.01.9-1.91.9-1.7-1.81.8-1.8-1.91.91.7
Reaction time num false alarms AUC1.11.62.0-1.41.3-1.31.31.3-1.3-1.2-1.3-1.3-1.3-1.31.2-1.31.3-1.1-1.21.2-1.2-1.21.21.1
Reaction time trials correct on left1.11.62.20.6-1.11.3-1.1-1.11.21.51.11.11.11.1-1.31.2-1.21.51.5-1.51.51.3-1.3-1.4
Reaction time trials on left1.11.62.20.6-1.11.2-1.1-1.11.11.51.11.11.11.1-1.31.2-1.21.51.5-1.51.51.3-1.3-1.4
Reaction time mean1.31.82.8-1.31.4-1.41.31.3-1.3-1.7-1.3-1.3-1.3-1.31.4-1.41.4-1.4-1.31.3-1.3-1.31.31.3
Reaction time mean AUC1.31.72.7-1.41.3-1.41.31.3-1.3-1.6-1.3-1.3-1.3-1.31.3-1.31.3-1.4-1.31.3-1.3-1.21.21.1
Median of all reaction times1.72.33.1-1.61.5-1.51.51.5-1.5-1.8-1.5-1.5-1.5-1.51.5-1.61.6-1.5-1.51.5-1.5-1.41.41.3
Reaction time omissions0.60.81.1-0.80.9-0.80.90.9-0.9-1.1-0.9-0.9-0.9-0.90.8-0.90.9-0.9-0.90.9-0.9-0.90.90.8
Reaction time false alarm rate2.53.43.8-1.71.9-1.91.91.8-1.8-1.9-1.9-1.9-1.9-1.91.9-1.91.9-1.8-1.81.8-1.8-1.81.81.8
Reaction time premature initiation rate0.20.31.10.60.3-0.70.30.4-0.4-0.5-0.5-0.5-0.5-0.50.6-0.50.5-0.5-0.60.6-0.6-0.60.71.0
Reaction time premature initiations0.10.21.11.0-0.50.2-0.5-0.50.40.50.30.30.30.3-0.30.3-0.30.50.4-0.40.40.3-0.30.0
Std. dev. reaction times0.50.71.5-0.10.7-0.90.70.7-0.7-1.2-0.8-0.8-0.8-0.80.8-0.90.9-0.8-0.70.7-0.7-0.90.91.1
Reaction time trials completed1.11.62.20.6-1.11.2-1.1-1.11.11.51.11.11.11.1-1.31.2-1.21.51.5-1.51.51.3-1.3-1.4
Reaction time trials AUC0.81.21.80.5-0.91.1-1.0-1.01.01.31.01.01.01.0-1.21.0-1.01.31.3-1.31.31.1-1.1-1.2
Run reversals in cocaine runway, females5.45.26.6-1.32.1-2.02.12.2-2.2-2.3-2.3-2.3-2.3-2.32.3-2.32.3-2.5-2.52.5-2.5-2.32.32.6
Run reversals in cocaine runway, males0.00.00.0-0.2-0.0-0.1-0.00.0-0.00.00.10.10.10.10.20.0-0.0-0.2-0.20.2-0.20.1-0.1-0.1
Latency to leave start box in cocaine runway4.34.65.4-2.12.1-2.12.12.1-2.1-2.1-2.2-2.2-2.2-2.22.2-2.22.2-2.3-2.32.3-2.3-2.02.01.9
Latency to leave start box in cocaine runway, F5.15.56.3-2.02.2-2.32.22.3-2.3-2.3-2.5-2.5-2.5-2.52.4-2.42.4-2.5-2.52.5-2.5-2.32.32.3
Latency to leave start box in cocaine runway, M0.00.00.2-0.40.00.00.00.1-0.10.00.00.00.00.0-0.00.0-0.0-0.0-0.00.0-0.00.1-0.1-0.2
Std. dev. time between licks in bursts0.40.41.30.50.5-0.70.50.5-0.5-0.4-0.7-0.7-0.7-0.70.6-0.70.7-0.7-0.60.6-0.6-0.80.81.2
Total sessions with >9 infusions3.53.85.72.2-2.22.4-2.1-2.02.02.02.02.02.02.0-2.02.0-2.01.61.5-1.51.52.0-2.0-1.8
Short access day 1 total inactive lever presses0.10.10.3-0.1-0.20.2-0.1-0.00.00.10.20.20.20.20.10.1-0.1-0.5-0.50.5-0.50.2-0.2-0.2
Short access day 10 total inactive lever presses0.00.00.1-0.30.10.00.10.1-0.1-0.1-0.1-0.1-0.1-0.1-0.0-0.10.10.10.1-0.10.1-0.10.10.0
Short access day 1 total infusions1.51.63.31.8-1.41.4-1.4-1.41.41.21.31.31.31.3-1.21.3-1.31.11.0-1.01.01.2-1.2-0.9
Short access day 10 total infusions0.40.51.61.3-0.81.0-0.8-0.80.80.60.70.70.70.7-0.70.7-0.70.50.4-0.40.40.6-0.6-0.4
Short access total infusions0.60.71.61.3-1.01.1-1.0-0.90.90.80.90.90.90.9-0.70.9-0.90.40.3-0.30.30.8-0.8-0.6
Short access day 1 locomotion3.73.94.41.8-2.12.1-2.0-2.02.02.02.12.12.12.1-1.92.1-2.11.81.7-1.71.72.0-2.0-2.0
Short access day 10 total locomotion0.10.10.40.5-0.10.2-0.1-0.20.20.10.10.10.10.1-0.40.1-0.10.50.7-0.70.70.0-0.00.1
Short access total locomotion0.20.20.60.5-0.50.8-0.4-0.40.40.40.40.40.40.4-0.60.4-0.40.40.3-0.30.30.4-0.4-0.4
One hour access (0.3 mA shock)1.31.52.91.7-1.31.3-1.3-1.31.31.21.21.21.21.2-1.21.2-1.21.21.1-1.11.11.1-1.1-0.9
Compulsive drug intake0.30.30.50.1-0.40.5-0.4-0.50.50.50.50.50.50.5-0.60.5-0.50.70.7-0.70.70.5-0.5-0.7
One hour access (shock baseline)0.60.72.01.4-0.90.8-0.9-0.90.90.80.80.80.80.8-0.80.8-0.80.80.7-0.70.70.7-0.7-0.5
Social response proportion0.91.01.1-0.70.9-1.00.91.0-1.0-1.0-1.0-1.0-1.0-1.01.0-0.90.9-1.0-1.01.0-1.0-1.01.01.0
Social responses1.72.22.6-0.91.4-1.51.41.4-1.4-1.6-1.5-1.5-1.5-1.51.5-1.41.4-1.6-1.61.6-1.6-1.51.51.6
Social time0.91.13.2-1.81.1-1.01.11.1-1.1-1.1-1.0-1.0-1.0-1.01.0-0.90.9-1.2-1.11.1-1.1-0.80.80.5
Soleus weight1.44.15.8-1.12.0-2.02.02.0-2.0-1.8-2.1-2.1-2.1-2.12.0-2.12.1-2.0-2.02.0-2.0-2.22.22.4
Bone: stiffness0.61.01.1-0.81.0-1.01.01.0-1.0-0.6-1.0-1.0-1.0-1.01.0-1.01.0-1.0-1.01.0-1.0-1.01.01.1
Tibialis anterior weight0.10.20.50.00.4-0.50.40.4-0.4-0.3-0.5-0.5-0.5-0.50.5-0.50.5-0.4-0.50.5-0.5-0.60.60.7
Time to tail flick, vehicle, before self-admin0.00.00.1-0.0-0.10.2-0.1-0.10.10.20.10.10.10.1-0.20.2-0.20.20.2-0.20.20.2-0.2-0.2
Time to tail flick, vehicle, after self-admin3.84.15.42.1-2.22.3-2.1-2.02.02.12.12.12.12.1-2.02.1-2.11.71.7-1.71.72.0-2.0-1.9
Time to tail flick, test, before self-admin0.00.00.10.4-0.1-0.0-0.0-0.00.0-0.00.00.00.00.00.1-0.00.0-0.1-0.20.2-0.2-0.10.10.2
Time to tail flick, test, after self-admin0.40.40.90.10.5-0.60.50.5-0.6-0.6-0.7-0.7-0.7-0.70.6-0.60.6-0.6-0.70.7-0.7-0.70.70.9
Delta time to tail flick, vehicle, before/after SA2.32.33.01.6-1.71.7-1.6-1.51.51.61.71.71.71.7-1.41.6-1.61.01.0-1.01.01.5-1.5-1.4
Delta time to tail flick, test, before/after SA0.40.40.4-0.60.6-0.50.60.6-0.6-0.6-0.6-0.6-0.6-0.60.6-0.60.6-0.6-0.60.6-0.6-0.60.60.5
Tibia length2.87.88.42.7-2.82.9-2.8-2.82.82.62.82.82.82.8-2.92.8-2.82.82.8-2.82.82.8-2.8-2.7
Ambulatory time before self-admin0.90.91.7-1.31.1-1.01.11.0-1.0-1.0-1.1-1.1-1.1-1.10.8-1.01.0-0.7-0.70.7-0.7-1.01.00.8
Ambulatory time after self-admin1.21.32.20.3-1.11.3-1.1-1.01.01.21.11.11.11.1-1.21.2-1.21.11.0-1.01.01.3-1.3-1.5
Bone: tissue strength0.70.71.40.1-0.80.9-0.8-0.80.80.90.90.90.90.9-0.80.8-0.80.80.8-0.80.81.0-1.0-1.2
Total heroin consumption0.70.80.90.8-0.91.0-0.9-0.90.90.90.90.90.90.9-0.90.9-0.90.90.9-0.90.90.9-0.9-0.9
Bone: trabecular number0.00.10.7-0.80.3-0.20.30.3-0.3-0.1-0.2-0.2-0.2-0.20.2-0.20.2-0.1-0.10.1-0.1-0.10.1-0.2
Bone: trabecular spacing0.81.01.91.2-1.00.9-1.0-1.01.01.41.01.01.01.0-0.91.0-1.00.90.9-0.90.90.9-0.9-0.8
Bone: trabecular thickness0.30.40.6-0.60.7-0.60.60.6-0.6-0.8-0.7-0.7-0.7-0.70.6-0.60.6-0.6-0.60.6-0.6-0.60.60.6
Bone: trabecular tissue density3.75.25.8-1.82.3-2.32.32.3-2.3-2.3-2.4-2.4-2.4-2.42.2-2.32.3-2.2-2.22.2-2.2-2.42.42.4
Water consumed over 24 hours0.10.20.6-0.80.5-0.40.40.4-0.4-0.2-0.4-0.4-0.4-0.40.4-0.40.4-0.4-0.40.4-0.4-0.30.30.2
Number of responses in last shaping day0.00.00.10.30.10.00.10.1-0.1-0.1-0.1-0.1-0.1-0.10.0-0.10.1-0.1-0.20.2-0.2-0.20.20.3