Hub : Genes

LOC120098979

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression LOC120098979 0.04 0.03 6.6e-06 0.04 0.04 0.03 0.03 3.0e-06 3.5e-06 1.4e-05 5.1e-06
2 Brain gene expression LOC120098979 0.07 0.04 1.3e-05 0.02 0.05 0.04 0.04 3.2e-03 1.4e-05 2.6e-04 2.7e-04
3 Brain mRNA stability LOC120098979 0.05 0.03 5.1e-05 0.04 0.05 0.04 0.05 5.2e-05 1.6e-05 5.6e-05 2.5e-05
4 pVTA gene expression LOC120098979 0.11 0.05 1.8e-08 0.08 0.1 0.1 0.1 9.5e-07 1.5e-08 4.3e-08 2.4e-08
5 PL gene expression LOC120098979 0.18 0.09 4.6e-07 0.07 0.06 0.06 0.06 2.4e-08 4.4e-07 3.2e-07 3.0e-07
6 BLA gene expression LOC120098979 0.19 0.1 9.3e-06 0.04 0.08 0.08 0.06 4.9e-03 4.7e-05 4.1e-05 5.1e-04
7 Liver mRNA stability LOC120098979 0.09 0.04 4.7e-08 0.06 0.06 0.07 0.05 3.0e-07 1.2e-07 7.1e-08 2.8e-06
8 Liver gene expression LOC120098979 0.39 0.11 3.0e-10 0.1 0.08 0.1 0.1 1.2e-11 1.3e-09 8.0e-11 1.9e-11

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density0.51.03.8-1.90.4-1.10.8-0.5-0.2-0.1-1.4
Area under the delay curve0.20.21.00.5-0.10.4-0.21.00.40.50.0
BMI with tail1.34.711.5-1.31.61.41.5-3.4-2.4-3.4-0.6
BMI without tail0.94.810.3-0.82.43.22.0-2.6-1.9-2.31.4
Body weight1.14.613.10.91.12.60.4-3.3-1.9-3.60.4
Weight adjusted by age0.41.03.11.20.11.5-0.3-0.9-0.5-1.8-0.7
Bone surface0.10.10.20.4-0.4-0.3-0.5-0.30.3-0.20.3
Bone volume0.10.20.8-0.70.3-0.10.4-0.9-0.3-0.6-0.2
Breakpoint value in progressive ratio session0.20.30.80.2-0.4-0.4-0.30.60.80.90.6
Number of licking bursts0.72.13.31.6-1.8-1.2-1.81.41.61.20.4
Context. condit. distance diff. score4.85.811.11.6-3.1-3.3-2.81.92.51.4-1.9
Locomotion velocity, session 11.01.22.90.7-0.8-0.5-0.81.71.41.50.1
Locomotion distance, session 10.30.41.1-1.0-0.1-1.00.20.40.30.4-1.0
Locomotion velocity, session 20.70.81.60.5-0.9-0.9-0.81.31.21.00.2
Locomotion distance, session 20.91.33.6-0.3-1.1-1.9-0.80.80.90.2-1.9
Locomotion velocity, session 30.50.61.2-0.81.01.01.1-0.2-0.30.30.8
Locomotion distance, session 30.60.71.4-0.8-0.3-1.20.01.10.81.1-0.7
Stereotopy head waving bouts, day 30.60.72.71.7-0.70.4-1.00.20.60.10.9
Stereotopy head waving duration, day 30.50.61.81.30.01.2-0.30.10.20.11.3
Locomotion velocity, session 72.73.08.5-0.9-1.4-2.9-0.81.31.20.6-2.9
Locomotion distance, session 72.12.77.0-1.1-1.1-2.6-0.51.81.31.5-2.1
Stereotopy head waving bouts, day 71.01.24.60.40.51.30.40.90.41.32.2
Stereotopy head waving duration, day 70.60.83.00.40.61.30.50.30.20.71.7
Locomotion velocity, session 84.85.88.82.8-2.9-1.9-3.02.43.01.80.0
Locomotion distance, session 84.87.016.91.1-3.3-4.1-2.91.72.50.9-2.9
Degree of sensitization distance0.80.81.71.1-1.3-1.0-1.30.60.80.2-0.2
Degree of sensitization stereotypy0.80.93.2-0.10.50.70.51.00.51.51.8
Conditioned locomotion0.40.51.40.8-0.6-0.1-0.7-0.8-0.2-1.2-0.7
Cocaine response after cond. corrected0.91.43.90.1-1.2-1.8-1.1-0.50.4-0.9-2.0
Cocaine response after cond. not corrected0.50.81.81.2-1.2-0.8-1.3-0.20.7-0.4-0.4
Cocaine response before conditioning1.82.28.31.70.52.4-0.00.20.10.62.9
Saline control response4.25.811.9-1.53.13.52.8-2.0-2.5-1.31.7
Bone: connectivity density0.60.92.8-1.2-0.2-1.40.1-0.6-0.1-0.6-1.7
Bone: cortical apparent density1.52.44.3-1.51.71.21.6-2.1-1.7-1.5-0.4
Bone: cortical area0.10.10.60.5-0.20.2-0.3-0.10.3-0.00.7
Bone: cortical porosity1.81.94.20.40.71.50.51.90.72.01.9
Bone: cortical porosity1.71.94.90.90.11.1-0.12.21.12.01.7
Bone: cortical thickness1.01.62.8-1.71.61.11.7-1.3-1.2-0.70.5
Bone: cortical thickness2.12.54.2-2.02.01.32.0-1.7-1.5-1.20.3
Bone: cortical tissue density1.32.13.9-1.41.61.21.6-2.0-1.6-1.5-0.3
Condit. Reinf. active minus inactive responses0.60.72.7-0.30.0-0.10.21.70.81.40.5
Condit. Reinf. active-inactive response ratio0.50.61.1-0.61.01.01.00.3-0.30.31.0
Condit. Reinf. active responses0.40.51.5-0.8-0.0-0.50.31.20.60.9-0.4
Condit. Reinf. inactive responses0.60.82.6-1.60.1-1.20.60.40.10.4-1.3
Incentive salience index mean1.92.44.60.6-1.6-1.8-1.42.11.91.5-0.7
Condit. Reinf. lever presses3.75.512.01.3-3.0-3.5-2.71.72.41.0-2.2
Condit. Reinf. active minus inactive responses0.40.62.10.70.41.40.2-0.1-0.10.21.4
Condit. Reinf. active-inactive response ratio0.40.72.01.4-0.21.1-0.50.10.40.21.4
Condit. Reinf. active responses0.20.41.30.10.51.00.4-0.1-0.30.31.1
Condit. Reinf. inactive responses0.30.51.0-1.00.90.51.0-0.5-0.8-0.20.3
Condit. Reinf. lever presses0.20.30.8-0.20.40.50.50.80.10.80.9
Condit. Reinf. lever reinforcers received0.30.41.90.20.40.90.30.3-0.00.61.4
Conditioned reinforcement - actives0.10.20.4-0.70.60.40.7-0.3-0.5-0.4-0.3
Conditioned reinforcement - inactives0.10.20.5-0.50.60.70.70.2-0.3-0.3-0.4
Conditioned locomotion0.10.10.80.0-0.00.1-0.00.30.30.0-0.9
Patch foraging indifference point 0 sec1.13.06.2-1.32.32.52.1-1.5-1.6-1.30.5
Patch foraging indifference point AUC0.20.62.00.40.20.70.10.50.81.01.4
Delay disc. indifference point, 0s delay0.70.81.41.0-1.1-0.8-1.20.90.80.2-0.7
Delay disc. indifference point, 16s delay0.20.30.8-0.70.90.80.90.2-0.10.0-0.1
Delay disc. indifference point, 2s delay0.91.02.31.5-0.70.4-1.01.41.10.70.3
Delay disc. indifference point, 24s delay0.20.41.60.20.71.30.50.80.10.20.0
Delay disc. indifference point, 4s delay0.40.41.40.90.11.1-0.20.4-0.20.11.2
Delay disc. indifference point, 8s delay0.20.31.20.2-0.2-0.1-0.21.10.40.8-0.4
Indifference point function ln k0.31.02.00.9-1.1-0.7-1.11.41.01.10.3
Indifference point function log k0.31.02.00.9-1.1-0.7-1.11.41.01.10.3
Patch foraging total patch changes 0 sec1.13.36.7-1.42.42.62.2-1.5-1.7-1.40.5
Patch foraging total patch changes 12 sec1.72.24.3-1.02.02.11.8-1.3-1.2-0.91.1
Patch foraging total patch changes 18 sec1.84.26.3-2.52.51.62.5-2.4-1.9-1.7-0.2
Patch foraging total patch changes 24 sec0.62.25.0-2.21.90.82.1-1.0-1.3-0.7-0.8
Patch foraging total patch changes 6 sec1.72.95.3-1.52.32.22.1-1.4-1.7-1.20.4
Patch foraging time to switch 0 sec0.72.56.6-1.20.5-0.30.6-2.1-1.8-2.6-1.9
Patch foraging water rate 0 sec0.00.10.30.30.20.50.00.00.1-0.1-0.2
Patch foraging water rate 12 sec0.10.41.0-1.00.80.20.9-0.4-0.50.10.2
Patch foraging water rate 18 sec0.10.20.5-0.20.70.70.6-0.3-0.6-0.4-0.2
Patch foraging water rate 24 sec0.30.40.7-0.60.70.60.7-0.7-0.7-0.30.8
Patch foraging water rate 6 sec0.10.10.3-0.50.50.20.6-0.4-0.20.00.0
Seeking ratio, delayed vs. immediate footshock1.21.88.9-0.01.11.60.9-0.5-0.10.63.0
Distance traveled before self-admin0.30.61.40.5-0.7-0.7-0.7-1.20.0-1.2-0.3
Distance traveled after self-admin0.50.93.40.70.31.10.0-1.1-0.4-0.81.8
Extensor digitorum longus weight0.20.71.71.3-1.1-0.5-1.20.10.8-0.3-0.2
Bone: elastic displacement0.50.61.3-1.01.10.81.10.5-0.20.5-0.2
Bone: elastic work0.10.10.5-0.20.50.70.40.1-0.0-0.1-0.1
Bone: endosteal estimation1.43.414.63.8-1.70.8-2.30.11.1-0.61.7
Bone: endosteal perimeter1.63.911.03.3-2.5-0.9-2.90.91.80.20.6
Epididymis fat weight4.522.533.1-5.45.13.15.2-5.8-5.5-4.8-1.4
Delta time in closed arm before/after self-admin0.30.20.50.4-0.20.1-0.4-0.6-0.7-0.7-0.5
Delta time in open arm before/after self-admin0.30.40.7-0.60.80.70.8-0.2-0.7-0.10.3
Diff in mean of infusions in LGA sessions0.81.45.6-0.3-1.3-2.4-0.90.81.00.9-0.9
Delay discount exponential model param0.20.31.2-0.60.0-0.60.2-1.1-0.3-0.6-0.2
Extinction: sum of active levers before priming0.71.11.81.0-1.3-1.0-1.21.01.40.7-0.4
Active lever presses in extinction session 60.40.41.7-0.70.50.20.70.2-0.1-0.1-1.3
Bone: final force1.11.74.5-0.51.01.20.8-2.1-1.2-2.10.1
Bone: final moment0.91.53.6-0.41.01.30.8-1.8-1.1-1.90.1
Food consumed during 24 hour testing period0.40.81.41.0-1.0-0.6-1.1-0.60.2-1.2-0.8
Glucose4.87.713.03.6-3.5-2.0-3.62.73.01.6-0.4
Heart weight0.60.94.01.30.52.00.10.2-0.2-0.11.2
Delay discount hyperbolic model param0.30.41.4-0.7-0.0-0.70.2-1.2-0.3-0.7-0.5
Intermittent access intake day 1-15 change0.10.31.7-0.40.40.30.4-0.20.00.61.3
Intermittent access intake escalation0.21.12.5-1.11.31.11.3-0.4-0.40.61.6
Intermittent access intake escalation 20.20.41.3-0.00.00.10.10.50.41.11.2
Intermitt. access day 1 inactive lever presses0.11.74.11.9-1.9-1.2-2.00.30.7-0.30.3
Intermitt. access day 15 inactive lever presses0.00.20.70.50.00.5-0.1-0.2-0.1-0.80.3
Intermitt. access escalation Index0.51.64.70.3-1.6-2.2-1.30.81.51.0-0.3
Intermittent access day 1 total infusions0.20.61.7-0.8-0.0-0.60.31.30.70.5-1.3
Intermittent access day 15 total infusions0.30.61.7-1.31.00.51.20.40.00.60.3
Intermittent access terminal intake (last 3 days)0.30.61.2-0.91.00.91.10.5-0.10.50.3
Intermittent access total infusions0.30.40.9-0.90.80.50.90.60.20.4-0.3
Intermittent access day 1 locomotion0.20.30.9-0.80.5-0.10.6-0.4-0.4-0.5-1.0
Intermittent access day 15 total locomotion0.10.41.0-0.40.70.80.6-1.0-0.4-0.60.2
Intermittent access total locomotion0.50.61.0-0.91.00.81.0-0.6-0.6-0.4-0.2
Intermittent access standard deviation0.42.34.2-0.81.72.11.5-1.7-1.8-1.40.5
Left kidney weight0.86.211.3-0.12.23.41.6-3.3-2.7-3.31.2
Right kidney weight0.85.712.50.11.72.81.1-3.5-2.9-3.50.7
Cocaine induced anxiety0.20.51.00.7-1.0-1.0-1.00.00.5-0.3-0.1
Post-drug Anxiety0.10.20.40.6-0.4-0.0-0.4-0.3-0.3-0.30.5
Baseline Anxiety0.10.10.40.10.40.60.3-0.1-0.60.30.2
Tail length0.63.18.72.9-0.32.5-1.10.41.00.22.7
Length with tail0.62.811.03.3-0.72.1-1.6-0.50.4-1.21.5
Length without tail0.63.210.52.3-0.90.7-1.5-2.3-0.9-3.2-0.8
Times rat made contact with spout1.41.64.2-2.01.60.71.90.4-0.31.01.0
Lifetime Intake0.30.40.7-0.80.70.50.80.60.10.2-0.5
Liver weight, left1.01.86.12.5-1.6-0.3-2.0-0.40.6-0.80.5
Liver weight, right1.42.57.32.7-2.0-0.4-2.30.81.4-0.40.5
Locomotor activity0.71.14.31.30.01.3-0.30.40.60.42.1
Locomotor testing distance0.20.41.21.1-0.40.5-0.60.20.70.00.9
Locomotor testing rearing0.10.30.90.8-0.30.5-0.5-0.70.1-0.90.4
Locomotion in novel chamber0.10.10.6-0.20.30.20.2-0.3-0.80.10.4
Locomotion in novel chamber post-restriction0.30.92.1-0.20.91.20.7-1.5-0.8-1.2-0.1
Fecal boli incidents, locomotor time 10.20.52.2-0.50.1-0.20.2-0.6-0.8-0.5-1.5
Change in fecal boli incidents, locomotor task1.21.33.21.8-1.3-0.4-1.50.61.20.11.0
Time >=10cm from walls, locomotor time 11.01.33.01.5-0.9-0.1-1.2-1.5-0.3-1.70.0
Bouts of movement, locomotor time 10.20.20.6-0.1-0.4-0.8-0.30.40.40.60.3
Total resting periods, locomotor time 10.20.20.60.1-0.5-0.7-0.40.40.60.50.1
Rest time, locomotor task time 10.10.20.40.6-0.40.1-0.50.40.20.40.4
Distance moved, locomotor task time 10.10.20.5-0.10.40.40.3-0.5-0.1-0.7-0.1
Vertical activity count, locomotor time 10.10.61.1-0.60.80.70.7-1.0-1.0-1.0-0.2
Time >=10cm from walls, locomotor time 20.20.72.41.6-0.70.3-1.1-0.30.2-0.7-0.6
Bouts of movement, locomotor time 20.20.62.70.30.10.60.00.6-0.40.91.7
Total resting periods, locomotor time 20.20.93.60.7-0.20.4-0.41.10.11.31.9
Rest time, locomotor task time 21.01.63.91.4-1.9-1.6-2.00.30.70.0-0.0
Distance moved, locomotor task time 21.01.33.0-0.91.21.01.1-1.0-0.5-1.3-1.7
Vertical activity count, locomotor time 20.30.81.8-0.40.80.80.7-0.7-1.0-1.1-1.3
Light reinforcement 10.20.73.0-0.40.0-0.40.0-1.7-0.8-1.3-0.7
Light reinforcement 20.30.61.20.4-0.7-0.7-0.7-1.0-0.2-1.1-1.0
Bone: marrow area1.33.314.13.8-1.51.0-2.2-0.10.9-0.71.7
Bone: maximum diameter1.53.15.62.4-2.2-1.2-2.31.51.91.00.7
Bone: maximum force0.50.93.2-0.00.60.90.4-1.5-0.8-1.8-0.2
Bone: maximum moment0.40.72.40.10.50.90.4-1.2-0.7-1.5-0.1
Mean time between licks in bursts0.53.24.92.0-2.2-1.5-2.21.72.01.60.4
Mean num. licks in bursts1.23.47.0-2.52.51.62.7-1.1-1.7-0.60.3
Cd content in liver1.41.66.6-1.10.3-0.50.5-1.1-0.8-1.5-2.6
Co content in liver1.41.63.8-0.81.11.11.0-1.6-1.3-1.9-0.9
Cu content in liver1.01.24.5-2.11.30.21.60.3-0.10.80.6
Fe content in liver1.11.42.0-1.21.31.01.3-1.4-1.3-1.2-0.2
K content in liver0.30.31.3-0.2-0.6-1.1-0.40.30.50.4-0.1
Mg content in liver2.72.95.11.6-2.3-2.1-2.11.31.81.20.4
Mn content in liver3.94.38.22.5-2.9-2.2-2.91.32.20.7-0.7
Na content in liver0.60.62.6-0.80.60.20.70.1-0.11.01.6
Rb content in liver0.40.41.1-0.0-0.6-1.1-0.5-0.3-0.1-0.8-0.9
Se content in liver4.25.08.12.3-2.3-1.3-2.22.82.62.41.3
Sr content in liver0.30.30.60.8-0.20.3-0.4-0.2-0.5-0.7-0.8
Zn content in liver0.30.30.60.6-0.8-0.6-0.70.30.6-0.2-0.5
Bone: minimum diameter1.32.56.92.6-2.0-0.7-2.30.51.60.10.2
Time in familiar zone, hab. session 11.61.75.8-2.41.70.42.00.2-0.80.6-0.0
Time in novel zone, hab. session 10.91.04.22.0-1.00.3-1.4-0.40.4-0.60.3
Total zone transitions, hab. session 10.20.30.8-0.0-0.6-0.9-0.50.40.50.50.2
Total locomotion distance, hab. session 10.20.31.3-0.2-0.6-1.1-0.50.10.40.2-0.6
Locomotion velocity, hab. session 10.10.20.6-0.1-0.5-0.8-0.40.20.30.3-0.0
Time in familiar zone, hab. session 20.91.01.5-1.21.20.71.2-0.9-1.1-0.41.2
Time in novel zone, hab. session 20.10.10.40.6-0.10.4-0.20.40.20.1-0.7
Total zone transitions, hab. session 20.20.20.8-0.3-0.4-0.9-0.3-0.6-0.1-0.5-0.3
Total locomotion distance, hab. session 20.60.83.4-0.5-0.9-1.8-0.6-0.40.1-0.3-1.1
Locomotion velocity, hab. session 20.81.14.7-0.3-1.2-2.2-0.90.00.60.1-1.1
Novel to familiar place preference ratio0.10.10.4-0.0-0.0-0.10.00.60.20.6-0.0
Novelty place preference0.10.20.60.20.00.1-0.00.70.30.80.3
Time in novel zone, NPP test0.20.20.60.20.10.40.00.70.20.80.5
Total zone transitions, NPP test0.71.03.3-0.2-1.0-1.8-0.70.60.80.3-1.4
Total locomotion distance, NPP test1.11.66.9-0.6-0.9-2.0-0.60.00.2-0.5-2.6
Locomotion velocity, NPP test1.52.18.0-0.7-1.2-2.5-0.70.10.4-0.3-2.8
Intraocular pressure0.50.92.2-1.50.9-0.01.1-0.9-0.6-0.7-1.2
Delta distance traveled before/after self-admin1.31.54.90.41.12.20.80.4-0.20.52.2
Delta ambulatory time before/after self-admin0.61.14.50.60.71.70.30.4-0.00.52.1
Parametrial fat weight1.73.910.2-1.51.50.81.4-3.0-1.8-3.2-1.3
Pavlov. Cond. lever latency5.16.49.5-1.92.82.62.6-3.1-3.0-2.70.6
Pavlov. Cond. magazine entry latency3.03.88.21.4-1.6-1.1-1.52.72.42.91.1
Pavlov. Cond. change in total contacts2.02.14.11.2-1.2-0.6-1.11.91.82.01.0
Pavlov. Cond. index score4.86.19.91.9-2.6-2.2-2.43.13.12.90.0
Pavlov. Cond. latency score5.16.510.22.0-2.7-2.3-2.53.23.13.00.1
Pavlov. Cond. lever contacts5.06.08.62.0-2.9-2.7-2.72.52.92.1-1.1
Pavlov. Cond. magazine entry number1.92.45.0-1.11.30.91.2-2.2-1.9-2.2-0.8
Pavlov. Cond. intertrial magazine entries1.72.03.9-2.01.40.51.6-1.3-1.5-1.4-1.3
Pavlov. Cond. lever-magazine prob. diff.4.75.99.81.8-2.5-2.2-2.33.13.02.90.0
Pavlov. Cond. response bias3.44.26.81.6-2.1-1.8-2.02.62.62.50.1
Pavlov. Cond. lever latency0.50.71.61.1-1.1-0.9-1.3-0.30.6-0.2-0.7
Pavlov. Cond. magazine entry latency0.10.20.60.3-0.5-0.3-0.50.80.50.4-0.1
Pavlov. Cond. change in total contacts0.30.71.6-0.41.01.20.90.5-0.40.51.3
Pavlov. Cond. index score0.10.20.5-0.20.40.50.40.70.00.40.7
Pavlov. Cond. latency score0.10.20.5-0.30.50.70.50.5-0.10.30.7
Pavlov. Cond. lever contacts0.40.61.3-0.91.10.81.10.2-0.60.10.7
Pavlov. Cond. magazine entry number0.00.00.10.10.10.20.0-0.2-0.10.10.4
Pavlov. Cond. intertrial magazine entries0.61.21.81.1-1.2-0.9-1.11.21.21.40.9
Pavlov. Cond. lever-magazine prob. diff.0.10.20.4-0.20.40.40.40.6-0.00.30.5
Pavlov. Cond. response bias0.10.20.6-0.40.30.10.40.80.10.50.5
Time in closed arm before self-admin0.10.20.50.6-0.30.1-0.40.20.70.00.3
Time in closed arm after self-admin0.00.00.10.2-0.10.0-0.2-0.1-0.1-0.30.2
Time in open arm before self-admin0.60.82.50.2-0.3-0.2-0.21.51.11.60.4
Time in open arm after self-admin0.30.30.6-0.10.40.70.40.80.10.70.6
Bone: periosteal estimation0.71.86.82.6-0.90.9-1.4-0.20.7-0.51.7
Bone: periosteal perimeter0.81.54.32.1-1.4-0.3-1.70.81.30.40.8
Bone: post-yield work0.81.43.41.8-1.6-0.9-1.80.10.7-0.6-0.5
Progressive ratio test 1 active lever presses0.10.10.7-0.20.10.00.10.50.3-0.3-0.8
Progressive ratio test 1 breakpoint0.10.10.6-0.10.00.10.10.50.3-0.3-0.8
Progressive ratio test 1 inactive lever presses0.30.81.6-1.00.5-0.10.6-1.0-1.2-1.2-0.7
Progressive ratio test 2 active lever presses0.10.20.8-0.90.3-0.30.50.4-0.00.4-0.1
Progressive ratio test 2 breakpoint0.20.31.1-1.00.4-0.20.60.4-0.00.5-0.0
Progressive ratio test 2 inactive lever presses0.20.61.40.4-0.8-0.6-0.71.20.80.4-0.8
Incentive Sensitization - Responses0.20.41.4-0.6-0.1-0.50.10.60.41.20.9
Incentive Sensitization - Breakpoint0.20.41.1-0.80.0-0.50.30.40.31.00.8
Sum of active levers in priming session hrs 5-60.30.30.90.5-0.30.1-0.40.90.80.6-0.2
Progressive ratio1.54.37.4-0.62.12.71.7-2.6-2.0-2.02.2
Food seeking constrained by brief footshock0.30.40.7-0.60.80.70.80.2-0.9-0.00.3
Seeking ratio, punishment vs. effort1.22.76.60.6-1.5-1.8-1.32.61.42.1-1.2
Retroperitoneal fat weight0.20.92.2-1.00.3-0.30.4-1.3-0.5-1.5-1.5
Reaction time number correct0.82.74.3-1.31.91.81.8-1.8-2.1-1.30.0
Reaction time mean minus median0.42.43.60.9-1.8-1.8-1.61.81.91.6-0.1
Reaction time mean minus median AUC0.42.64.20.7-1.8-2.0-1.52.01.91.5-0.9
Reaction time num false alarms0.50.81.30.9-0.9-0.5-0.90.70.91.21.1
Reaction time num false alarms AUC0.51.23.01.2-0.8-0.2-0.90.81.01.41.7
Reaction time trials correct on left0.82.74.3-1.31.91.81.8-1.8-2.1-1.30.0
Reaction time trials on left0.82.64.1-1.21.91.81.8-1.8-2.0-1.30.0
Reaction time mean1.84.17.11.6-2.6-2.7-2.51.81.90.6-1.7
Reaction time mean AUC1.63.86.61.4-2.5-2.6-2.31.81.80.6-1.7
Median of all reaction times2.03.15.41.4-2.3-2.3-2.21.31.40.1-1.9
Reaction time omissions1.32.03.81.2-1.9-1.9-1.91.11.50.6-0.8
Reaction time false alarm rate2.53.44.61.9-1.9-1.2-1.91.92.22.11.6
Reaction time premature initiation rate0.20.30.90.40.10.5-0.0-0.7-0.6-1.0-0.5
Reaction time premature initiations0.61.83.1-0.31.31.61.0-1.7-1.7-1.7-0.3
Std. dev. reaction times1.23.96.01.7-2.3-1.9-2.22.42.41.70.0
Reaction time trials completed0.82.64.1-1.21.91.81.8-1.8-2.0-1.30.0
Reaction time trials AUC0.72.53.9-1.21.81.71.7-1.8-2.0-1.3-0.1
Run reversals in cocaine runway, females0.70.82.1-0.80.90.50.9-0.8-1.5-0.6-0.9
Run reversals in cocaine runway, males0.50.50.90.7-0.9-0.8-1.00.70.80.6-0.1
Latency to leave start box in cocaine runway1.11.52.71.0-1.7-1.6-1.61.01.40.4-0.5
Latency to leave start box in cocaine runway, F0.81.02.10.7-1.3-1.4-1.20.80.90.4-0.6
Latency to leave start box in cocaine runway, M0.40.40.70.7-0.8-0.6-0.80.20.7-0.2-0.0
Std. dev. time between licks in bursts2.13.97.72.8-2.5-1.2-2.71.72.11.10.5
Total sessions with >9 infusions0.30.30.6-0.50.70.80.70.70.10.5-0.0
Short access day 1 total inactive lever presses0.40.92.41.0-0.9-0.3-0.91.51.00.3-0.8
Short access day 10 total inactive lever presses0.10.62.00.2-1.0-1.4-0.9-0.2-0.2-0.10.7
Short access day 1 total infusions0.20.41.60.1-0.10.0-0.11.30.70.4-1.1
Short access day 10 total infusions0.20.30.8-0.90.60.10.70.3-0.2-0.1-0.6
Short access total infusions0.20.31.0-0.50.40.20.40.90.30.2-1.0
Short access day 1 locomotion0.30.51.6-0.0-0.8-1.2-0.60.60.40.7-0.2
Short access day 10 total locomotion0.20.82.31.5-0.50.8-0.8-0.50.3-0.61.5
Short access total locomotion0.10.20.60.7-0.6-0.1-0.70.00.3-0.2-0.1
One hour access (0.3 mA shock)0.60.72.3-0.5-0.6-1.5-0.30.70.41.20.4
Compulsive drug intake2.53.68.71.5-2.7-2.9-2.60.31.70.90.6
One hour access (shock baseline)0.51.43.2-1.81.61.01.80.3-0.90.1-0.3
Social response proportion0.40.52.21.5-0.60.5-0.80.30.6-0.50.1
Social responses0.40.51.41.2-0.20.8-0.40.50.60.11.2
Social time2.23.46.32.1-2.5-2.0-2.51.21.70.81.0
Soleus weight2.67.720.84.6-3.6-1.8-4.01.22.50.3-0.2
Bone: stiffness0.50.92.6-0.70.70.50.7-1.6-0.9-1.50.0
Tibialis anterior weight0.31.01.9-1.41.20.81.3-1.1-0.8-0.70.5
Time to tail flick, vehicle, before self-admin0.30.42.0-0.4-0.5-1.4-0.3-0.70.10.00.0
Time to tail flick, vehicle, after self-admin0.40.71.10.7-0.9-0.9-0.81.01.00.9-0.3
Time to tail flick, test, before self-admin0.40.41.4-0.70.70.40.8-0.1-0.10.41.2
Time to tail flick, test, after self-admin0.50.61.7-0.80.0-0.70.41.10.51.30.2
Delta time to tail flick, vehicle, before/after SA0.50.51.7-0.30.20.10.31.30.30.7-1.2
Delta time to tail flick, test, before/after SA0.30.41.6-0.7-0.1-0.80.1-0.1-0.3-0.3-1.3
Tibia length0.82.28.52.9-1.20.7-1.8-1.10.4-1.30.7
Ambulatory time before self-admin0.00.10.40.1-0.3-0.5-0.2-0.60.2-0.5-0.2
Ambulatory time after self-admin0.40.62.60.70.31.20.1-0.6-0.0-0.31.6
Bone: tissue strength0.30.31.3-0.00.10.20.1-0.6-0.4-1.0-1.1
Total heroin consumption0.10.10.30.5-0.3-0.1-0.30.10.40.50.6
Bone: trabecular number0.81.55.4-2.30.5-1.31.0-0.6-0.2-0.1-1.8
Bone: trabecular spacing0.71.04.22.1-0.31.3-0.80.10.0-0.31.2
Bone: trabecular thickness0.81.13.5-1.90.4-0.90.8-0.8-0.5-0.5-1.5
Bone: trabecular tissue density0.40.72.60.30.51.20.40.40.11.01.6
Water consumed over 24 hours0.20.40.70.8-0.8-0.5-0.90.50.80.30.2
Number of responses in last shaping day1.41.94.72.2-1.20.3-1.51.51.61.00.9