Hub : Genes

LOC120098978

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression LOC120098978 0.14 0.07 2.2e-08 0.06 0.08 0.05 0.08 5.9e-06 2.6e-07 4.6e-05 3.8e-07
2 Adipose mRNA stability LOC120098978 0.4 0.18 0.0e+00 0.21 0.22 0.21 0.2 2.7e-23 1.3e-23 1.5e-22 4.1e-22
3 Adipose gene expression LOC120098978 0.06 0.03 7.8e-06 0.02 0.03 0.01 0.02 3.6e-03 1.4e-04 7.2e-03 4.8e-03
4 Brain gene expression LOC120098978 0.1 0.05 1.1e-07 0.05 0.07 0.06 0.07 1.4e-05 4.1e-07 5.1e-06 3.4e-07
5 IC gene expression LOC120098978 0.07 0.05 7.8e-03 0.02 0.03 0.05 0.01 4.9e-02 2.2e-02 3.4e-03 1.0e-01
6 OFC gene expression LOC120098978 0.18 0.1 3.5e-03 0.02 0.09 0.03 0.03 1.2e-01 4.7e-03 8.2e-02 7.1e-02
7 BLA gene expression LOC120098978 0.1 0.05 3.7e-04 0.04 0.06 0.04 0.05 5.6e-03 7.2e-04 5.7e-03 7.5e-04
8 NAcc gene expression LOC120098978 0.14 0.06 0.0e+00 0.1 0.14 0.14 0.14 1.2e-15 3.3e-20 8.6e-21 1.7e-20
9 PL gene expression LOC120098978 0.11 0.05 3.5e-10 0.04 0.09 0.07 0.06 1.5e-05 4.7e-10 4.3e-08 1.5e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.20.51.2-0.7-0.7-0.2-0.50.6-1.1-1.10.3-0.5
Area under the delay curve0.20.30.80.60.5-0.20.60.50.80.9-0.30.7
BMI with tail0.82.89.81.52.63.10.9-1.20.1-1.0-0.5-1.6
BMI without tail1.05.28.32.72.82.92.0-2.72.31.5-2.00.6
Body weight0.94.012.12.13.23.51.0-2.31.10.0-0.5-1.3
Weight adjusted by age0.10.41.50.60.81.20.3-0.90.50.30.1-0.4
Bone surface0.10.20.5-0.5-0.4-0.2-0.70.0-0.5-0.50.2-0.4
Bone volume0.00.10.2-0.2-0.10.2-0.2-0.2-0.4-0.40.1-0.3
Breakpoint value in progressive ratio session0.10.20.4-0.5-0.5-0.7-0.50.5-0.2-0.10.40.1
Number of licking bursts0.41.32.2-1.3-1.3-1.5-1.51.1-0.9-0.51.0-0.4
Context. condit. distance diff. score7.38.812.9-3.6-3.2-2.7-3.43.2-3.2-2.42.8-1.8
Locomotion velocity, session 10.81.03.0-1.1-1.7-1.6-0.70.7-0.20.50.20.7
Locomotion distance, session 10.30.40.8-0.7-0.8-0.6-0.50.9-0.8-0.70.1-0.3
Locomotion velocity, session 20.40.51.1-0.7-0.8-1.1-0.71.0-0.4-0.10.30.1
Locomotion distance, session 21.42.03.6-1.4-1.0-0.8-1.31.9-1.7-1.71.4-1.3
Locomotion velocity, session 30.91.11.71.00.60.31.3-1.01.21.2-1.31.1
Locomotion distance, session 30.50.51.2-0.8-1.1-1.1-0.31.1-0.7-0.40.20.1
Stereotopy head waving bouts, day 30.00.10.20.10.3-0.1-0.2-0.10.40.40.00.0
Stereotopy head waving duration, day 30.50.61.40.60.40.20.4-0.81.11.2-0.60.8
Locomotion velocity, session 74.44.89.3-2.3-1.8-1.4-1.93.1-2.6-2.42.2-1.6
Locomotion distance, session 72.63.36.7-2.1-2.2-2.0-1.42.6-1.9-1.41.6-0.4
Stereotopy head waving bouts, day 72.12.45.31.10.2-0.51.2-1.22.02.3-1.72.2
Stereotopy head waving duration, day 71.51.93.31.20.50.01.2-1.31.71.8-1.81.6
Locomotion velocity, session 82.93.55.7-2.4-2.4-2.4-2.41.9-1.6-0.81.5-0.7
Locomotion distance, session 88.211.916.0-3.9-3.2-2.5-3.83.8-4.0-3.43.2-2.7
Degree of sensitization distance0.90.91.5-1.1-0.9-0.8-1.21.0-0.9-0.71.2-0.7
Degree of sensitization stereotypy1.41.63.90.7-0.3-0.80.9-0.81.41.9-1.62.0
Conditioned locomotion0.50.51.6-0.30.40.6-0.60.2-0.7-1.00.8-1.3
Cocaine response after cond. corrected1.92.85.9-1.4-0.30.0-1.61.5-2.1-2.41.8-2.2
Cocaine response after cond. not corrected0.50.71.5-0.7-0.1-0.1-1.00.6-1.0-1.11.0-1.2
Cocaine response before conditioning3.03.67.31.70.90.31.4-2.22.62.7-1.92.0
Saline control response6.38.812.53.42.92.53.3-3.53.22.6-2.82.0
Bone: connectivity density0.91.43.1-1.2-0.8-0.1-1.10.9-1.7-1.80.8-1.3
Bone: cortical apparent density1.11.83.81.71.91.91.5-1.30.90.2-1.0-0.0
Bone: cortical area0.00.10.30.20.30.10.0-0.20.30.2-0.50.0
Bone: cortical porosity3.33.69.31.0-0.4-1.11.3-1.02.43.0-1.63.0
Bone: cortical porosity2.32.56.90.5-0.8-1.40.7-0.61.92.6-1.22.6
Bone: cortical thickness1.11.83.21.71.61.31.5-1.21.20.8-1.80.7
Bone: cortical thickness2.22.74.92.12.21.91.8-1.61.30.6-1.70.4
Bone: cortical tissue density1.01.73.51.61.91.91.4-1.30.90.3-1.0-0.0
Condit. Reinf. active minus inactive responses0.50.61.70.0-0.7-1.00.40.50.61.0-0.51.3
Condit. Reinf. active-inactive response ratio1.11.21.91.20.70.31.2-0.71.41.3-1.41.3
Condit. Reinf. active responses0.20.20.8-0.3-0.6-0.70.10.9-0.10.20.10.5
Condit. Reinf. inactive responses0.40.51.2-0.6-0.6-0.4-0.21.1-1.0-0.90.8-0.4
Incentive salience index mean1.72.24.5-1.7-1.8-1.9-1.42.1-1.2-0.71.2-0.2
Condit. Reinf. lever presses5.78.510.9-3.3-2.7-2.2-3.23.3-3.3-2.83.0-2.2
Condit. Reinf. active minus inactive responses0.50.81.80.80.40.20.6-1.11.31.4-0.61.0
Condit. Reinf. active-inactive response ratio0.20.41.10.30.0-0.10.1-0.80.91.1-0.20.7
Condit. Reinf. active responses0.40.51.10.60.20.10.6-0.81.01.0-0.70.9
Condit. Reinf. inactive responses0.30.40.70.80.70.60.8-0.60.60.4-0.90.4
Condit. Reinf. lever presses0.40.61.60.0-0.7-0.70.4-0.30.71.1-0.71.2
Condit. Reinf. lever reinforcers received0.40.61.50.5-0.0-0.20.6-0.81.01.2-0.71.1
Conditioned reinforcement - actives0.00.10.20.10.20.40.30.50.10.00.20.1
Conditioned reinforcement - inactives0.00.10.30.20.20.30.50.10.40.40.10.3
Conditioned locomotion0.10.20.9-0.4-0.5-0.1-0.10.9-0.2-0.10.6-0.1
Patch foraging indifference point 0 sec1.54.26.62.62.32.12.3-2.22.21.7-1.61.2
Patch foraging indifference point AUC0.40.92.10.80.1-0.40.9-0.51.31.5-0.91.4
Delay disc. indifference point, 0s delay0.60.61.2-0.8-0.4-0.6-0.81.1-0.8-0.61.1-0.7
Delay disc. indifference point, 16s delay0.60.81.41.00.70.41.2-0.01.11.0-1.00.9
Delay disc. indifference point, 2s delay0.30.30.8-0.0-0.2-0.6-0.00.80.60.90.30.7
Delay disc. indifference point, 24s delay1.01.63.51.20.60.11.4-0.51.71.9-1.31.6
Delay disc. indifference point, 4s delay0.70.71.51.01.00.30.7-0.51.21.2-0.20.8
Delay disc. indifference point, 8s delay0.10.20.30.30.2-0.30.40.40.40.5-0.30.5
Indifference point function ln k0.20.61.4-0.8-0.9-1.1-0.81.2-0.4-0.10.40.1
Indifference point function log k0.20.61.4-0.8-0.9-1.1-0.81.2-0.4-0.10.40.1
Patch foraging total patch changes 0 sec1.64.67.12.72.42.12.4-2.22.31.8-1.71.3
Patch foraging total patch changes 12 sec2.83.75.12.31.91.52.1-2.22.11.7-1.91.4
Patch foraging total patch changes 18 sec1.43.35.82.32.42.32.0-2.01.30.6-1.70.4
Patch foraging total patch changes 24 sec0.41.22.81.41.21.11.7-1.10.90.6-0.80.7
Patch foraging total patch changes 6 sec2.33.85.92.42.01.92.4-2.02.11.6-1.61.2
Patch foraging time to switch 0 sec0.51.84.8-0.11.11.7-0.5-0.2-1.3-2.10.7-2.2
Patch foraging water rate 0 sec0.00.10.20.50.40.40.5-0.20.50.40.00.2
Patch foraging water rate 12 sec0.00.20.30.60.50.30.5-0.00.40.2-0.50.4
Patch foraging water rate 18 sec0.20.40.70.80.80.80.8-0.20.60.4-0.40.2
Patch foraging water rate 24 sec0.30.41.00.70.70.60.6-1.00.50.3-0.80.3
Patch foraging water rate 6 sec0.10.20.50.60.70.50.5-0.10.30.0-0.30.1
Seeking ratio, delayed vs. immediate footshock2.53.65.92.01.50.61.6-2.32.22.1-2.41.8
Distance traveled before self-admin0.51.02.6-0.7-0.00.5-1.3-0.3-1.2-1.50.8-1.6
Distance traveled after self-admin0.61.04.20.91.10.90.4-2.10.80.6-0.90.1
Extensor digitorum longus weight0.20.81.5-1.1-0.7-0.3-1.20.4-1.0-0.91.1-1.0
Bone: elastic displacement0.70.91.80.90.30.11.1-0.71.21.3-0.81.3
Bone: elastic work0.20.30.50.70.50.40.5-0.40.70.6-0.40.5
Bone: endosteal estimation0.10.31.1-0.6-0.2-0.1-1.0-0.4-0.00.10.9-0.7
Bone: endosteal perimeter0.92.14.8-1.8-1.4-1.1-2.21.1-1.3-1.01.6-1.3
Epididymis fat weight2.211.331.84.05.35.63.2-2.71.5-0.5-2.0-0.9
Delta time in closed arm before/after self-admin0.50.51.1-0.30.30.6-0.50.5-0.6-0.81.0-1.0
Delta time in open arm before/after self-admin0.50.51.50.60.50.30.6-1.20.70.7-1.00.7
Diff in mean of infusions in LGA sessions1.62.86.2-1.7-1.3-1.1-1.42.5-2.0-1.81.6-1.3
Delay discount exponential model param0.40.51.3-0.7-0.50.2-0.7-0.3-1.0-1.10.4-1.0
Extinction: sum of active levers before priming0.81.33.4-1.2-1.1-0.9-1.21.8-1.0-0.71.3-0.6
Active lever presses in extinction session 60.00.00.2-0.0-0.10.20.20.5-0.1-0.10.30.0
Bone: final force1.01.74.71.52.12.20.9-1.30.6-0.2-0.6-0.7
Bone: final moment0.81.33.71.31.81.90.9-1.20.6-0.0-0.6-0.5
Food consumed during 24 hour testing period0.61.23.3-0.60.20.5-1.00.6-1.2-1.51.4-1.8
Glucose3.75.99.5-3.0-3.1-2.8-3.02.4-2.0-1.02.5-0.9
Heart weight1.11.73.41.20.70.61.2-1.51.81.8-1.21.2
Delay discount hyperbolic model param0.50.71.7-0.7-0.50.3-0.7-0.2-1.2-1.30.4-1.1
Intermittent access intake day 1-15 change0.10.41.40.60.40.00.5-0.20.70.7-1.20.7
Intermittent access intake escalation0.41.93.81.51.00.51.5-1.01.61.5-1.91.5
Intermittent access intake escalation 20.20.30.70.2-0.1-0.40.20.20.60.8-0.70.8
Intermitt. access day 1 inactive lever presses0.22.13.4-1.6-0.7-0.7-1.91.5-1.6-1.51.6-1.6
Intermitt. access day 15 inactive lever presses0.00.10.20.10.30.40.0-0.30.10.0-0.3-0.2
Intermitt. access escalation Index0.82.63.6-1.7-1.2-1.3-1.81.8-1.9-1.71.6-1.2
Intermittent access day 1 total infusions0.20.71.8-1.0-1.3-0.9-0.31.3-0.6-0.20.90.2
Intermittent access day 15 total infusions0.20.61.40.60.1-0.11.00.10.81.0-0.71.2
Intermittent access terminal intake (last 3 days)0.40.71.80.6-0.0-0.01.1-0.11.11.3-0.71.3
Intermittent access total infusions0.20.30.90.2-0.2-0.20.70.20.60.8-0.21.0
Intermittent access day 1 locomotion0.00.10.3-0.2-0.10.20.10.4-0.3-0.30.6-0.2
Intermittent access day 15 total locomotion0.10.50.80.90.80.90.7-0.30.70.4-0.80.1
Intermittent access total locomotion0.30.40.80.80.60.70.9-0.00.70.6-0.50.5
Intermittent access standard deviation0.52.54.01.92.01.91.8-1.51.61.0-1.30.5
Left kidney weight0.86.212.93.03.63.62.0-2.92.11.0-1.7-0.1
Right kidney weight0.74.712.72.43.43.61.5-2.51.40.2-1.1-0.9
Cocaine induced anxiety0.30.81.3-0.9-0.4-0.3-1.10.6-1.1-1.11.1-1.1
Post-drug Anxiety0.10.10.3-0.10.30.2-0.50.3-0.3-0.40.5-0.6
Baseline Anxiety0.10.20.40.50.50.30.4-0.10.60.5-0.60.4
Tail length0.42.36.11.20.70.30.7-2.02.32.5-1.01.5
Length with tail0.21.01.91.01.31.10.1-1.41.41.20.0-0.1
Length without tail0.52.68.00.11.72.2-0.9-0.3-0.9-1.81.5-2.8
Times rat made contact with spout1.72.03.71.40.70.01.8-0.71.51.6-1.71.9
Lifetime Intake0.20.20.70.2-0.2-0.10.70.30.50.7-0.00.8
Liver weight, left0.40.82.0-0.9-0.3-0.1-1.40.1-0.8-0.81.0-1.3
Liver weight, right0.71.23.1-1.2-0.7-0.6-1.81.0-0.8-0.61.6-1.1
Locomotor activity0.71.02.30.90.60.00.6-0.91.41.5-1.21.1
Locomotor testing distance0.00.10.20.20.40.1-0.1-0.10.40.4-0.20.1
Locomotor testing rearing0.10.20.60.10.60.7-0.4-0.4-0.1-0.40.5-0.7
Locomotion in novel chamber0.10.10.30.40.60.30.4-0.10.20.10.10.1
Locomotion in novel chamber post-restriction0.30.82.21.11.41.50.8-1.00.60.2-0.4-0.2
Fecal boli incidents, locomotor time 10.30.71.5-0.8-0.40.3-0.90.7-1.0-1.11.2-0.9
Change in fecal boli incidents, locomotor task0.10.10.3-0.20.0-0.4-0.5-0.1-0.1-0.00.5-0.3
Time >=10cm from walls, locomotor time 11.11.44.1-0.30.81.1-1.20.7-1.0-1.51.0-2.0
Bouts of movement, locomotor time 10.10.10.5-0.3-0.3-0.7-0.2-0.1-0.2-0.0-0.40.2
Total resting periods, locomotor time 10.10.10.6-0.4-0.5-0.7-0.3-0.1-0.3-0.1-0.10.1
Rest time, locomotor task time 10.20.30.8-0.6-0.5-0.5-0.70.4-0.20.10.90.0
Distance moved, locomotor task time 10.20.51.20.80.80.70.8-0.80.60.3-1.10.1
Vertical activity count, locomotor time 10.21.22.91.31.71.31.1-0.90.60.1-1.4-0.2
Time >=10cm from walls, locomotor time 20.10.30.70.20.60.6-0.50.1-0.0-0.20.8-0.8
Bouts of movement, locomotor time 20.20.71.70.60.3-0.50.4-0.41.11.3-0.91.3
Total resting periods, locomotor time 20.20.82.10.3-0.1-1.00.1-0.21.01.4-0.81.4
Rest time, locomotor task time 21.62.75.0-1.8-1.0-0.9-2.21.6-1.9-1.71.7-1.6
Distance moved, locomotor task time 20.81.02.11.21.01.41.4-1.10.70.4-0.80.0
Vertical activity count, locomotor time 20.20.61.41.01.01.20.9-0.50.50.2-0.4-0.1
Light reinforcement 10.20.92.40.31.01.3-0.1-0.4-0.7-1.40.1-1.5
Light reinforcement 20.51.13.3-0.50.30.7-0.70.3-1.2-1.61.0-1.8
Bone: marrow area0.10.30.9-0.4-0.00.1-0.9-0.50.10.20.8-0.7
Bone: maximum diameter0.81.62.8-1.6-1.5-1.5-1.71.3-1.1-0.61.0-0.6
Bone: maximum force0.40.72.30.81.31.50.5-0.80.3-0.3-0.3-0.7
Bone: maximum moment0.20.41.60.61.01.30.4-0.70.3-0.1-0.2-0.5
Mean time between licks in bursts0.42.74.8-2.1-2.2-2.0-2.21.4-1.3-0.61.4-0.4
Mean num. licks in bursts1.13.05.72.11.61.42.4-1.61.71.4-1.91.4
Cd content in liver1.01.12.9-0.50.10.9-0.40.5-1.3-1.71.1-1.6
Co content in liver0.91.03.31.01.41.80.8-1.00.3-0.3-0.4-0.6
Cu content in liver0.60.81.50.90.50.01.2-0.20.90.8-1.01.2
Fe content in liver0.60.72.11.01.21.40.7-1.00.4-0.0-0.2-0.2
K content in liver0.70.61.0-1.0-0.9-0.7-0.90.8-1.0-0.80.5-0.5
Mg content in liver2.73.04.5-2.1-1.9-1.8-2.11.8-1.8-1.41.2-1.0
Mn content in liver4.24.77.5-2.4-1.8-1.5-2.72.4-2.3-1.92.3-1.8
Na content in liver0.60.71.30.80.4-0.21.0-0.50.91.0-1.11.1
Rb content in liver1.11.22.1-1.1-0.6-0.1-1.10.8-1.4-1.51.4-1.3
Se content in liver1.61.96.2-1.5-1.9-2.5-1.21.5-0.50.30.60.6
Sr content in liver0.20.20.4-0.4-0.30.2-0.30.1-0.4-0.40.7-0.6
Zn content in liver0.50.50.8-0.9-0.7-0.3-0.90.6-0.9-0.80.6-0.8
Bone: minimum diameter0.71.33.2-1.3-0.9-0.7-1.80.8-1.1-0.91.2-1.2
Time in familiar zone, hab. session 10.90.92.10.90.20.01.3-0.50.91.0-1.31.4
Time in novel zone, hab. session 10.20.20.6-0.30.10.2-0.6-0.1-0.2-0.30.6-0.8
Total zone transitions, hab. session 10.30.40.7-0.8-0.7-0.7-0.80.6-0.7-0.50.2-0.2
Total locomotion distance, hab. session 10.50.71.2-1.0-0.7-0.6-1.10.9-1.0-0.90.7-0.6
Locomotion velocity, hab. session 10.20.30.7-0.7-0.6-0.5-0.80.6-0.6-0.50.4-0.3
Time in familiar zone, hab. session 20.91.02.21.21.10.70.9-1.00.90.6-1.50.7
Time in novel zone, hab. session 20.00.10.2-0.1-0.3-0.10.30.00.20.30.40.2
Total zone transitions, hab. session 20.40.61.5-0.50.10.2-0.80.4-1.0-1.20.5-1.1
Total locomotion distance, hab. session 21.52.04.1-1.3-0.5-0.3-1.61.4-1.9-2.01.3-1.6
Locomotion velocity, hab. session 22.02.74.4-1.6-0.9-0.7-1.91.7-2.1-2.11.5-1.6
Novel to familiar place preference ratio0.10.10.3-0.1-0.4-0.50.10.20.20.40.30.6
Novelty place preference0.20.20.70.1-0.3-0.50.2-0.00.50.70.10.8
Time in novel zone, NPP test0.30.31.00.2-0.3-0.50.3-0.20.71.0-0.01.0
Total zone transitions, NPP test1.52.23.4-1.7-1.5-1.0-1.61.4-1.8-1.61.1-1.1
Total locomotion distance, NPP test2.43.45.7-1.8-1.2-0.5-1.82.0-2.4-2.41.9-1.9
Locomotion velocity, NPP test3.34.77.8-2.2-1.4-0.7-2.12.3-2.8-2.82.1-2.2
Intraocular pressure0.10.20.40.40.20.60.6-0.6-0.0-0.2-0.4-0.0
Delta distance traveled before/after self-admin3.13.46.31.71.10.31.8-1.72.42.5-1.82.1
Delta ambulatory time before/after self-admin1.42.54.81.51.00.21.5-1.52.12.2-1.51.8
Parametrial fat weight1.12.58.31.32.22.90.9-1.3-0.3-1.40.1-1.8
Pavlov. Cond. lever latency4.76.012.63.03.53.42.5-2.61.80.7-2.00.1
Pavlov. Cond. magazine entry latency1.51.96.6-1.2-2.1-2.6-0.91.00.00.90.31.3
Pavlov. Cond. change in total contacts0.80.93.2-0.8-1.4-1.8-0.60.70.10.80.31.0
Pavlov. Cond. index score3.34.210.2-2.4-3.0-3.2-2.12.1-1.2-0.21.60.4
Pavlov. Cond. latency score3.64.510.9-2.5-3.1-3.3-2.22.2-1.3-0.21.60.4
Pavlov. Cond. lever contacts5.36.310.5-3.1-3.2-2.9-2.82.6-2.3-1.32.5-0.8
Pavlov. Cond. magazine entry number1.01.34.51.11.82.10.8-0.90.1-0.7-0.4-1.0
Pavlov. Cond. intertrial magazine entries0.50.62.10.71.01.41.0-0.4-0.1-0.6-0.3-0.6
Pavlov. Cond. lever-magazine prob. diff.3.34.19.9-2.4-3.0-3.1-2.12.2-1.2-0.21.50.4
Pavlov. Cond. response bias2.32.86.9-2.0-2.5-2.6-1.71.8-1.0-0.11.30.3
Pavlov. Cond. lever latency0.71.01.9-0.8-0.2-0.0-1.20.7-1.1-1.21.2-1.4
Pavlov. Cond. magazine entry latency0.20.30.8-0.7-0.9-0.7-0.60.4-0.3-0.00.50.1
Pavlov. Cond. change in total contacts0.51.32.60.80.1-0.11.1-1.01.41.6-1.21.6
Pavlov. Cond. index score0.20.41.10.2-0.4-0.40.4-0.30.71.0-0.61.0
Pavlov. Cond. latency score0.30.41.10.4-0.2-0.20.5-0.50.81.0-0.71.0
Pavlov. Cond. lever contacts0.50.81.40.80.20.11.1-0.71.01.1-1.11.2
Pavlov. Cond. magazine entry number0.10.10.20.30.30.20.3-0.20.30.2-0.40.1
Pavlov. Cond. intertrial magazine entries0.20.51.7-0.7-1.0-1.3-0.70.6-0.30.1-0.00.3
Pavlov. Cond. lever-magazine prob. diff.0.20.30.80.2-0.3-0.30.4-0.30.60.8-0.50.9
Pavlov. Cond. response bias0.20.30.80.0-0.5-0.50.4-0.00.40.7-0.40.9
Time in closed arm before self-admin0.00.10.2-0.1-0.4-0.20.10.20.20.30.30.2
Time in closed arm after self-admin0.20.21.1-0.3-0.10.2-0.30.4-0.3-0.41.0-0.5
Time in open arm before self-admin0.50.61.5-0.3-1.0-1.20.10.60.40.9-0.21.1
Time in open arm after self-admin0.50.61.40.3-0.3-0.40.5-0.70.81.1-1.01.2
Bone: periosteal estimation0.00.10.40.00.30.2-0.4-0.60.40.40.0-0.3
Bone: periosteal perimeter0.10.30.9-0.6-0.5-0.7-0.90.5-0.20.00.3-0.3
Bone: post-yield work1.11.83.2-1.6-1.1-0.5-1.80.9-1.5-1.41.5-1.5
Progressive ratio test 1 active lever presses0.10.21.0-0.4-0.5-0.2-0.11.0-0.20.00.60.0
Progressive ratio test 1 breakpoint0.10.20.9-0.4-0.5-0.2-0.11.0-0.10.00.60.1
Progressive ratio test 1 inactive lever presses0.10.30.70.00.60.80.10.5-0.5-0.80.4-0.8
Progressive ratio test 2 active lever presses0.10.10.9-0.2-0.3-0.30.10.9-0.2-0.00.30.3
Progressive ratio test 2 breakpoint0.10.10.7-0.1-0.2-0.30.30.80.00.10.20.4
Progressive ratio test 2 inactive lever presses0.31.12.3-1.3-1.2-0.8-0.91.5-0.9-0.61.2-0.4
Incentive Sensitization - Responses0.10.20.6-0.3-0.4-0.7-0.10.7-0.00.10.00.5
Incentive Sensitization - Breakpoint0.10.10.4-0.3-0.3-0.6-0.10.6-0.10.00.00.4
Sum of active levers in priming session hrs 5-60.20.20.5-0.4-0.6-0.7-0.40.60.10.40.10.5
Progressive ratio2.05.89.82.93.12.72.0-3.02.21.4-2.50.6
Food seeking constrained by brief footshock0.40.51.10.70.50.21.0-0.70.80.8-0.30.8
Seeking ratio, punishment vs. effort1.22.85.8-2.0-2.4-2.4-1.22.0-1.2-0.31.50.2
Retroperitoneal fat weight0.20.92.2-0.10.61.2-0.20.4-0.9-1.41.0-1.5
Reaction time number correct0.62.23.51.71.61.91.8-1.91.30.8-1.40.4
Reaction time mean minus median0.42.54.4-1.9-2.1-2.0-1.71.6-1.4-0.81.3-0.4
Reaction time mean minus median AUC0.53.56.1-2.3-2.5-2.1-2.02.0-1.7-1.01.8-0.5
Reaction time num false alarms0.10.20.7-0.4-0.3-0.9-0.50.5-0.00.20.20.3
Reaction time num false alarms AUC0.10.30.8-0.0-0.2-0.9-0.20.20.50.7-0.40.7
Reaction time trials correct on left0.62.23.51.71.61.91.8-1.91.30.8-1.40.4
Reaction time trials on left0.62.13.41.71.61.81.7-1.81.30.8-1.40.4
Reaction time mean2.55.67.7-2.8-2.3-1.9-2.62.4-2.6-2.12.6-1.8
Reaction time mean AUC2.25.37.1-2.7-2.2-1.8-2.52.5-2.5-2.02.6-1.7
Median of all reaction times3.04.76.2-2.4-1.8-1.3-2.32.2-2.5-2.22.5-2.0
Reaction time omissions1.82.94.2-2.0-1.7-1.4-2.01.7-1.9-1.51.6-1.3
Reaction time false alarm rate0.81.13.9-1.1-1.2-2.0-1.21.2-0.30.30.50.5
Reaction time premature initiation rate0.10.10.40.10.30.60.2-0.6-0.1-0.30.3-0.5
Reaction time premature initiations0.41.33.01.21.31.71.2-1.60.70.3-0.5-0.2
Std. dev. reaction times0.93.15.5-2.2-2.3-2.3-2.01.8-1.4-0.61.5-0.3
Reaction time trials completed0.62.13.41.71.61.81.7-1.81.30.8-1.40.4
Reaction time trials AUC0.51.93.41.61.51.81.6-1.71.10.6-1.30.2
Run reversals in cocaine runway, females0.10.10.60.40.50.80.3-0.30.1-0.1-0.1-0.1
Run reversals in cocaine runway, males0.50.51.0-1.0-1.0-1.0-0.90.4-0.7-0.30.4-0.2
Latency to leave start box in cocaine runway1.72.43.6-1.7-1.3-1.1-1.71.9-1.6-1.41.8-1.2
Latency to leave start box in cocaine runway, F1.62.03.6-1.5-1.1-1.0-1.41.9-1.4-1.21.7-1.0
Latency to leave start box in cocaine runway, M0.40.40.6-0.6-0.3-0.2-0.80.4-0.7-0.80.6-0.8
Std. dev. time between licks in bursts1.22.34.5-2.0-1.9-1.8-2.11.1-1.2-0.51.5-0.6
Total sessions with >9 infusions0.50.61.50.50.1-0.20.9-0.01.01.2-0.51.2
Short access day 1 total inactive lever presses0.50.92.2-1.2-1.1-0.9-0.81.2-0.7-0.31.5-0.3
Short access day 10 total inactive lever presses0.21.12.1-0.9-0.1-0.4-1.20.9-1.3-1.51.0-1.2
Short access day 1 total infusions0.20.30.7-0.5-0.8-0.70.10.80.10.40.50.5
Short access day 10 total infusions0.00.10.2-0.0-0.1-0.10.40.20.10.20.10.4
Short access total infusions0.10.20.5-0.2-0.4-0.40.30.70.10.40.40.5
Short access day 1 locomotion0.40.71.1-1.0-0.8-1.0-0.81.1-0.9-0.60.8-0.3
Short access day 10 total locomotion0.10.30.60.50.70.3-0.1-0.80.70.6-0.40.1
Short access total locomotion0.10.20.4-0.4-0.1-0.1-0.50.6-0.3-0.20.6-0.4
One hour access (0.3 mA shock)0.70.82.7-0.9-0.8-1.1-0.71.6-0.9-0.60.3-0.1
Compulsive drug intake3.04.48.4-2.2-1.3-1.4-2.91.6-2.6-2.51.5-2.2
One hour access (shock baseline)0.40.92.40.90.40.31.6-0.21.11.1-0.71.3
Social response proportion0.10.10.5-0.10.10.2-0.40.70.0-0.00.5-0.4
Social responses0.10.20.50.40.40.20.10.20.70.6-0.10.3
Social time1.93.16.1-1.9-1.2-1.5-2.51.9-1.8-1.51.7-1.3
Soleus weight1.64.89.7-2.6-1.9-1.6-3.11.8-2.1-1.72.5-2.1
Bone: stiffness0.30.61.90.81.31.40.5-0.60.1-0.5-0.3-0.7
Tibialis anterior weight0.20.81.61.11.31.10.9-1.00.60.2-0.90.2
Time to tail flick, vehicle, before self-admin0.40.51.4-0.20.30.0-0.80.7-0.9-1.20.1-0.9
Time to tail flick, vehicle, after self-admin0.20.41.1-0.7-0.9-1.0-0.40.5-0.4-0.00.40.1
Time to tail flick, test, before self-admin0.60.71.10.80.5-0.00.9-0.90.90.9-0.91.1
Time to tail flick, test, after self-admin0.40.41.4-0.6-1.0-1.2-0.00.2-0.10.30.10.9
Delta time to tail flick, vehicle, before/after SA0.40.41.0-0.4-1.0-0.80.40.60.20.60.20.8
Delta time to tail flick, test, before/after SA0.60.71.3-0.9-0.6-0.1-0.80.7-1.1-1.20.8-0.9
Tibia length0.20.41.3-0.20.40.6-0.8-1.0-0.2-0.30.6-1.2
Ambulatory time before self-admin0.10.40.7-0.5-0.30.1-0.9-0.3-0.7-0.80.4-0.8
Ambulatory time after self-admin0.50.83.20.80.80.60.4-1.80.90.8-0.80.4
Bone: tissue strength0.20.20.5-0.10.10.5-0.00.1-0.4-0.50.7-0.7
Total heroin consumption0.00.00.1-0.1-0.2-0.3-0.20.2-0.00.00.10.0
Bone: trabecular number0.30.61.5-0.8-0.8-0.2-0.50.8-1.2-1.20.3-0.6
Bone: trabecular spacing0.50.71.40.90.90.50.6-1.11.21.1-0.30.4
Bone: trabecular thickness0.40.51.6-0.5-0.20.2-0.30.6-1.1-1.30.4-0.8
Bone: trabecular tissue density0.81.43.60.7-0.1-0.51.0-1.11.51.9-0.81.8
Water consumed over 24 hours0.10.20.4-0.5-0.4-0.5-0.60.5-0.4-0.30.5-0.3
Number of responses in last shaping day0.30.41.1-0.5-0.8-1.0-0.4-0.00.40.90.50.6