LOC120098961

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression LOC120098961 0.18 0.1 1.7e-07 0.11 0.12 0.14 0.13 2.1e-06 4.1e-07 5.7e-08 1.5e-07
2 Liver gene expression LOC120098961 0.05 0.04 2.6e-04 0.02 0.01 0.01 0.01 2.7e-03 1.6e-02 8.8e-03 7.9e-03
3 PL gene expression LOC120098961 0.04 0.03 7.1e-05 0.03 0.03 0.02 0.03 1.2e-04 4.8e-04 6.5e-03 5.4e-04
4 Brain gene expression LOC120098961 0.08 0.05 4.2e-05 0.05 0.03 0.03 0.04 4.2e-05 1.1e-03 3.9e-04 1.0e-04
5 Brain mRNA stability LOC120098961 0.04 0.03 2.5e-03 0.04 0.02 0.03 0.03 3.3e-04 7.6e-03 1.5e-03 1.0e-03
6 IC gene expression LOC120098961 0.12 0.06 1.9e-05 0.11 0.11 0.11 0.11 3.0e-05 2.7e-05 3.3e-05 1.6e-05
7 pVTA gene expression LOC120098961 0.12 0.08 2.8e-04 0.02 0.03 0.03 0.01 7.2e-03 3.2e-03 3.9e-03 1.9e-02
8 Adipose gene expression LOC120098961 0.06 0.03 5.9e-10 0.07 0.08 0.08 0.07 5.0e-08 2.5e-09 5.8e-09 1.3e-08
9 NAcc gene expression LOC120098961 0.3 0.16 3.6e-10 0.07 0.07 0.06 0.07 2.3e-11 1.1e-10 5.1e-10 1.4e-10
10 BLA mRNA stability LOC120098961 0.14 0.08 2.1e-04 0.03 0.09 0.06 0.06 1.4e-02 2.7e-05 3.4e-04 5.1e-04
11 PL mRNA stability LOC120098961 0.05 0.03 5.6e-03 0.01 0.02 0 0.01 5.6e-02 4.7e-03 2.4e-01 1.8e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.10.20.70.3-0.10.20.30.30.20.80.40.10.50.7
Area under the delay curve0.20.20.60.4-0.5-0.1-0.5-0.5-0.20.1-0.6-0.40.80.6
BMI with tail1.13.99.8-1.4-3.1-2.0-1.8-1.8-2.3-1.2-2.6-1.9-0.9-1.9
BMI without tail1.03.04.7-1.2-2.1-1.6-2.0-2.0-1.7-1.4-2.2-1.6-0.8-1.7
Body weight2.29.718.8-1.7-2.4-3.6-4.1-4.1-3.0-3.4-4.3-3.40.1-1.3
Weight adjusted by age0.40.62.91.1-0.5-0.0-0.1-0.10.10.5-0.6-0.31.71.4
Bone surface0.00.10.3-0.10.5-0.2-0.2-0.2-0.0-0.50.0-0.30.00.2
Bone volume0.00.00.10.0-0.1-0.3-0.2-0.2-0.2-0.2-0.3-0.30.30.2
Breakpoint value in progressive ratio session0.80.92.3-1.3-0.8-1.5-0.6-0.6-1.2-0.7-0.5-0.9-1.0-0.8
Number of licking bursts0.40.61.50.21.20.50.70.70.9-0.40.90.9-0.7-0.6
Context. condit. distance diff. score0.60.83.80.72.00.80.60.61.0-0.21.10.30.00.4
Locomotion velocity, session 12.42.64.22.11.91.81.71.71.91.01.51.61.31.2
Locomotion distance, session 13.03.85.91.81.52.32.42.42.21.62.32.40.40.6
Locomotion velocity, session 20.30.41.60.41.30.50.40.40.6-0.40.80.4-0.5-0.2
Locomotion distance, session 21.01.42.21.11.01.31.31.31.21.01.31.50.60.8
Locomotion velocity, session 30.60.71.51.00.81.10.80.80.9-0.80.30.9-0.5-1.2
Locomotion distance, session 31.61.83.91.51.22.01.61.61.60.41.21.5-0.1-0.5
Stereotopy head waving bouts, day 30.80.93.5-0.30.4-1.0-1.0-1.0-0.6-1.9-1.0-1.0-0.5-0.8
Stereotopy head waving duration, day 30.10.10.40.30.6-0.2-0.3-0.30.0-0.4-0.1-0.30.30.4
Locomotion velocity, session 71.21.32.31.40.61.41.11.11.11.20.71.21.51.2
Locomotion distance, session 72.32.93.91.91.22.01.71.71.71.81.41.71.81.8
Stereotopy head waving bouts, day 70.30.41.20.80.50.50.20.20.4-1.0-0.30.1-0.4-1.1
Stereotopy head waving duration, day 70.30.41.70.30.00.1-0.2-0.2-0.0-1.1-0.6-0.2-0.7-1.3
Locomotion velocity, session 80.50.64.20.62.00.30.30.30.8-0.80.70.10.20.5
Locomotion distance, session 81.11.64.61.12.11.51.31.31.50.21.71.10.10.5
Degree of sensitization distance0.80.81.8-1.0-0.3-1.2-1.0-1.0-0.80.2-0.5-1.00.81.4
Degree of sensitization stereotypy0.60.61.41.10.61.20.80.80.9-0.10.50.7-0.5-0.9
Conditioned locomotion3.13.55.3-1.7-1.1-2.2-2.3-2.3-2.2-1.9-2.0-2.2-0.9-0.9
Cocaine response after cond. corrected0.81.01.6-1.3-0.8-1.0-0.8-0.8-0.9-1.1-0.8-0.8-1.0-1.2
Cocaine response after cond. not corrected0.60.71.8-0.9-0.2-0.8-0.8-0.8-0.7-1.3-0.6-0.8-1.0-1.0
Cocaine response before conditioning0.30.31.50.91.20.50.10.10.5-0.30.40.00.40.5
Saline control response1.82.45.1-1.8-2.3-1.6-1.7-1.7-1.9-0.1-1.6-1.8-0.3-0.2
Bone: connectivity density0.10.20.90.2-0.1-0.00.00.0-0.00.70.2-0.20.71.0
Bone: cortical apparent density0.40.51.4-1.0-1.2-0.5-0.5-0.5-0.8-0.2-0.5-0.5-0.9-0.9
Bone: cortical area0.10.20.50.40.20.30.60.60.60.00.20.70.4-0.0
Bone: cortical porosity1.61.73.92.00.91.51.21.21.31.10.71.31.51.1
Bone: cortical porosity2.12.34.82.11.01.41.21.21.41.50.71.42.21.9
Bone: cortical thickness0.81.32.60.7-0.51.31.61.61.11.30.81.60.2-0.3
Bone: cortical thickness0.50.63.4-1.0-1.8-0.5-0.3-0.3-0.80.4-0.5-0.2-0.5-0.7
Bone: cortical tissue density0.40.61.2-0.9-1.1-0.5-0.6-0.6-0.9-0.3-0.5-0.6-0.9-0.8
Condit. Reinf. active minus inactive responses0.91.03.41.00.10.60.50.50.51.60.60.51.51.8
Condit. Reinf. active-inactive response ratio0.40.40.8-0.5-0.9-0.7-0.7-0.7-0.80.4-0.5-0.80.00.4
Condit. Reinf. active responses0.50.62.30.5-0.50.20.00.0-0.01.30.00.11.31.5
Condit. Reinf. inactive responses0.30.31.20.3-0.50.50.30.30.21.10.20.30.90.8
Incentive salience index mean0.70.82.01.20.70.70.60.60.80.90.60.61.31.4
Condit. Reinf. lever presses0.30.51.10.91.00.40.60.60.80.10.50.60.80.7
Condit. Reinf. active minus inactive responses0.30.41.10.50.80.60.30.30.60.60.70.40.61.0
Condit. Reinf. active-inactive response ratio0.10.10.50.30.60.20.00.00.30.20.30.20.40.7
Condit. Reinf. active responses0.30.51.00.60.80.60.50.50.70.70.80.50.61.0
Condit. Reinf. inactive responses0.00.00.0-0.0-0.1-0.1-0.0-0.00.0-0.1-0.0-0.20.0-0.0
Condit. Reinf. lever presses1.92.65.51.51.31.61.41.41.42.41.91.31.22.1
Condit. Reinf. lever reinforcers received0.81.11.71.11.11.00.90.91.11.21.20.90.91.3
Conditioned reinforcement - actives0.40.63.81.90.20.20.20.20.80.3-0.20.31.30.6
Conditioned reinforcement - inactives0.40.52.91.70.40.80.20.20.90.70.40.20.60.5
Conditioned locomotion0.60.83.31.2-0.70.1-0.6-0.6-0.00.4-0.9-0.41.81.3
Patch foraging indifference point 0 sec0.20.41.7-0.3-1.3-0.8-0.5-0.5-0.7-0.1-1.0-0.5-0.1-0.5
Patch foraging indifference point AUC0.30.41.70.41.30.70.50.50.6-0.40.80.5-0.5-0.2
Delay disc. indifference point, 0s delay0.10.10.40.6-0.10.10.30.30.30.30.10.20.60.4
Delay disc. indifference point, 16s delay0.20.30.90.8-0.00.40.30.30.50.4-0.10.41.00.6
Delay disc. indifference point, 2s delay0.40.51.90.90.10.50.10.10.31.00.40.21.11.4
Delay disc. indifference point, 24s delay0.50.62.21.0-0.80.1-0.2-0.2-0.10.5-0.9-0.11.51.0
Delay disc. indifference point, 4s delay0.70.71.4-0.6-0.6-0.6-1.2-1.2-0.9-0.7-0.9-1.2-0.2-0.2
Delay disc. indifference point, 8s delay0.40.41.0-0.0-0.7-0.3-0.8-0.8-0.5-0.1-1.0-0.80.90.7
Indifference point function ln k0.30.51.11.01.00.60.80.80.90.10.60.70.30.1
Indifference point function log k0.30.51.11.01.00.60.80.80.90.10.60.70.30.1
Patch foraging total patch changes 0 sec0.20.31.7-0.1-1.3-0.6-0.4-0.4-0.60.0-0.9-0.4-0.1-0.5
Patch foraging total patch changes 12 sec0.10.10.70.1-0.00.20.20.20.1-0.10.20.3-0.7-0.8
Patch foraging total patch changes 18 sec0.71.12.2-0.8-1.5-0.8-0.9-0.9-1.0-0.7-1.1-0.8-1.1-1.4
Patch foraging total patch changes 24 sec0.10.21.1-0.0-1.10.30.20.2-0.21.00.10.0-0.2-0.0
Patch foraging total patch changes 6 sec0.20.31.6-0.6-1.3-0.0-0.3-0.3-0.80.3-0.5-0.3-0.4-0.5
Patch foraging time to switch 0 sec1.53.17.2-2.2-2.7-1.9-1.7-1.7-2.2-0.6-1.8-1.7-0.8-0.9
Patch foraging water rate 0 sec0.30.61.41.20.90.80.70.70.90.50.50.80.60.5
Patch foraging water rate 12 sec0.20.51.10.90.71.00.80.80.80.20.70.7-0.4-0.5
Patch foraging water rate 18 sec0.10.20.8-0.3-0.4-0.2-0.1-0.1-0.30.9-0.1-0.10.50.9
Patch foraging water rate 24 sec0.30.40.90.20.60.70.50.50.6-0.00.70.6-0.9-0.8
Patch foraging water rate 6 sec0.20.40.60.00.70.60.70.70.6-0.10.70.8-0.5-0.5
Seeking ratio, delayed vs. immediate footshock1.31.53.9-2.0-0.1-0.9-0.7-0.7-0.8-1.6-0.4-0.7-2.0-1.8
Distance traveled before self-admin1.21.63.8-1.10.0-1.1-1.1-1.1-0.8-1.9-0.9-1.2-1.7-1.8
Distance traveled after self-admin1.82.23.6-1.8-0.1-1.9-1.5-1.5-1.1-1.9-1.0-1.6-1.7-1.5
Extensor digitorum longus weight0.10.63.40.51.80.20.40.40.6-0.10.90.40.30.9
Bone: elastic displacement1.21.43.01.70.41.61.11.11.11.30.61.21.31.0
Bone: elastic work0.30.41.30.8-0.40.50.40.40.21.0-0.00.51.11.0
Bone: endosteal estimation2.14.78.6-2.0-0.5-2.9-2.7-2.7-2.1-2.7-2.4-2.5-0.2-0.3
Bone: endosteal perimeter1.32.85.5-1.5-0.1-2.1-2.1-2.1-1.6-2.3-1.6-1.9-0.8-0.7
Epididymis fat weight1.86.028.1-2.1-5.3-1.2-1.9-1.9-2.50.5-2.3-1.6-1.9-2.7
Delta time in closed arm before/after self-admin0.50.41.60.4-1.3-0.6-0.6-0.6-0.6-0.1-1.1-0.50.5-0.2
Delta time in open arm before/after self-admin0.10.10.20.30.40.00.30.30.30.20.50.30.10.3
Diff in mean of infusions in LGA sessions0.20.31.3-1.1-0.3-0.3-0.2-0.2-0.70.10.1-0.4-0.8-0.1
Delay discount exponential model param0.20.20.6-0.40.5-0.00.40.40.2-0.20.50.4-0.8-0.6
Extinction: sum of active levers before priming0.10.10.30.10.50.10.30.30.4-0.10.40.4-0.3-0.4
Active lever presses in extinction session 60.80.82.50.7-1.1-0.2-0.0-0.0-0.11.5-0.4-0.01.61.6
Bone: final force2.33.76.4-2.0-2.5-2.2-1.9-1.9-2.1-1.5-2.5-1.7-0.7-1.4
Bone: final moment1.62.54.6-1.5-2.2-1.8-1.6-1.6-1.8-1.1-2.1-1.5-0.4-1.0
Food consumed during 24 hour testing period2.83.86.8-2.6-1.5-2.4-2.3-2.3-2.3-1.1-1.7-2.5-0.9-0.3
Glucose1.21.94.51.82.11.00.80.81.40.41.01.31.71.6
Heart weight3.35.17.02.51.21.92.42.42.22.61.72.22.62.6
Delay discount hyperbolic model param0.10.20.6-0.50.2-0.20.30.3-0.0-0.30.30.2-0.8-0.7
Intermittent access intake day 1-15 change0.81.72.7-1.6-0.9-1.5-1.1-1.1-1.5-1.5-1.2-1.1-1.3-1.4
Intermittent access intake escalation0.81.72.6-1.5-1.3-1.6-1.1-1.1-1.6-1.3-1.3-1.1-1.1-1.3
Intermittent access intake escalation 20.20.20.7-0.6-0.1-0.8-0.1-0.1-0.4-0.7-0.5-0.20.1-0.1
Intermitt. access day 1 inactive lever presses0.31.13.0-0.51.70.20.60.60.8-0.91.30.6-1.7-1.4
Intermitt. access day 15 inactive lever presses0.30.61.9-0.80.2-0.8-0.8-0.8-0.4-1.4-0.6-0.7-0.6-0.9
Intermitt. access escalation Index0.50.82.8-0.70.90.20.40.40.1-0.70.90.5-1.7-1.5
Intermittent access day 1 total infusions3.65.817.84.21.01.71.91.92.52.51.32.03.12.6
Intermittent access day 15 total infusions0.40.63.11.8-0.20.20.60.60.50.70.10.61.10.6
Intermittent access terminal intake (last 3 days)0.70.94.62.1-0.10.50.70.70.80.80.10.71.40.8
Intermittent access total infusions1.61.97.72.80.30.90.90.91.31.40.60.91.91.5
Intermittent access day 1 locomotion0.20.31.71.30.10.3-0.2-0.20.50.3-0.0-0.10.80.6
Intermittent access day 15 total locomotion1.42.55.2-0.9-1.6-1.6-2.1-2.1-1.3-1.4-2.3-2.10.1-0.4
Intermittent access total locomotion0.50.61.40.5-0.7-0.5-1.2-1.2-0.3-0.2-1.0-1.10.80.6
Intermittent access standard deviation1.12.33.8-1.3-1.3-1.9-1.6-1.6-1.6-1.4-1.6-1.7-1.0-1.3
Left kidney weight1.25.510.1-1.1-1.5-2.5-3.1-3.1-2.2-3.0-3.2-2.3-0.3-1.6
Right kidney weight2.310.418.0-2.2-2.2-3.5-4.2-4.2-3.1-3.9-4.1-3.3-0.7-2.0
Cocaine induced anxiety0.50.73.0-1.70.7-0.3-0.2-0.2-0.2-1.20.2-0.3-1.1-0.8
Post-drug Anxiety0.90.95.8-2.40.0-0.6-0.7-0.7-0.8-0.8-0.1-0.7-1.0-0.4
Baseline Anxiety0.40.52.0-0.5-1.4-0.5-0.6-0.6-1.00.7-0.6-0.6-0.10.2
Tail length0.41.86.0-0.41.3-1.1-1.9-1.9-0.4-2.5-1.2-1.10.2-0.2
Length with tail0.93.78.3-0.30.7-2.3-2.7-2.7-1.1-2.9-2.4-1.81.20.5
Length without tail1.23.88.0-0.4-1.1-2.5-2.6-2.6-1.8-1.9-2.8-2.11.20.5
Times rat made contact with spout0.60.73.30.1-0.21.00.80.80.61.81.00.70.30.8
Lifetime Intake1.11.45.92.4-0.00.60.60.61.01.20.20.61.91.4
Liver weight, left1.62.64.9-1.5-0.2-2.0-1.9-1.9-1.7-2.2-1.6-2.0-0.7-0.7
Liver weight, right2.03.59.8-1.01.2-1.5-2.7-2.7-1.1-3.1-1.4-2.1-1.0-1.0
Locomotor activity0.50.83.0-0.70.5-0.4-0.2-0.2-0.1-1.6-0.1-0.1-1.6-1.7
Locomotor testing distance0.50.93.0-1.2-0.4-0.7-0.3-0.3-0.6-1.0-0.2-0.4-1.7-1.7
Locomotor testing rearing1.32.64.2-2.0-0.9-1.5-1.6-1.6-1.6-1.9-1.3-1.7-1.8-1.8
Locomotion in novel chamber0.70.82.01.40.60.41.21.20.91.00.80.90.70.6
Locomotion in novel chamber post-restriction1.11.82.9-1.4-1.7-1.5-1.5-1.5-1.5-0.7-1.7-1.5-0.5-0.7
Fecal boli incidents, locomotor time 10.30.51.2-0.4-0.8-0.4-0.7-0.7-0.60.5-0.6-0.70.91.1
Change in fecal boli incidents, locomotor task0.50.40.8-0.6-0.4-0.5-0.7-0.7-0.5-0.6-0.4-0.8-0.9-0.9
Time >=10cm from walls, locomotor time 15.05.38.9-3.0-2.0-2.6-2.2-2.2-2.7-2.1-2.0-2.5-2.0-1.9
Bouts of movement, locomotor time 10.40.51.8-1.30.3-0.6-0.3-0.3-0.3-0.80.2-0.6-1.2-0.8
Total resting periods, locomotor time 10.50.62.7-1.60.3-0.6-0.5-0.5-0.4-0.9-0.1-0.7-0.9-0.5
Rest time, locomotor task time 10.60.71.31.01.11.11.01.01.00.10.50.70.70.4
Distance moved, locomotor task time 10.60.91.6-1.0-1.0-1.2-1.1-1.1-1.1-0.5-0.8-0.8-0.6-0.6
Vertical activity count, locomotor time 11.74.17.3-2.5-2.1-2.7-2.4-2.4-2.4-1.0-1.9-2.1-0.9-0.8
Time >=10cm from walls, locomotor time 22.23.36.9-1.3-2.6-2.1-1.8-1.8-2.3-0.9-2.4-2.10.2-0.3
Bouts of movement, locomotor time 21.01.65.4-2.30.3-0.9-1.1-1.1-0.8-1.6-0.4-1.5-1.6-1.0
Total resting periods, locomotor time 20.50.93.2-1.80.9-0.3-0.6-0.6-0.3-1.30.2-1.0-1.5-0.8
Rest time, locomotor task time 20.40.51.3-0.51.10.20.00.00.3-1.00.4-0.1-1.1-1.0
Distance moved, locomotor task time 21.72.05.2-0.5-2.3-1.5-1.4-1.4-1.60.1-2.1-1.21.10.6
Vertical activity count, locomotor time 21.52.13.8-1.0-2.0-1.5-1.6-1.6-1.60.1-1.8-1.31.21.0
Light reinforcement 12.15.17.3-2.7-1.8-2.5-2.0-2.0-2.2-2.5-2.0-2.0-2.3-2.6
Light reinforcement 22.84.35.9-2.3-1.5-2.3-2.3-2.3-2.4-2.1-2.0-2.4-1.4-1.4
Bone: marrow area2.35.09.3-2.2-0.6-3.0-2.8-2.8-2.3-2.8-2.5-2.5-0.3-0.3
Bone: maximum diameter0.10.31.60.31.3-0.1-0.0-0.00.4-0.90.10.00.40.3
Bone: maximum force0.30.61.5-0.7-1.2-1.0-0.6-0.6-0.7-0.6-1.2-0.40.2-0.3
Bone: maximum moment0.20.30.8-0.2-0.8-0.6-0.4-0.4-0.4-0.2-0.9-0.20.70.2
Mean time between licks in bursts0.81.89.61.33.10.90.90.91.5-0.71.60.9-0.20.2
Mean num. licks in bursts0.30.42.1-0.0-0.90.3-0.0-0.0-0.31.4-0.1-0.30.81.0
Cd content in liver0.91.02.3-0.4-1.5-0.7-0.8-0.8-0.91.2-0.8-0.81.31.5
Co content in liver2.12.47.2-1.3-2.7-1.5-1.6-1.6-1.9-0.0-2.0-1.50.2-0.1
Cu content in liver1.01.13.20.2-0.31.21.31.30.91.81.31.3-0.00.2
Fe content in liver0.50.71.5-0.4-0.7-0.8-0.8-0.8-0.8-1.2-1.2-0.7-0.2-0.8
K content in liver1.31.32.21.31.51.31.11.11.40.71.21.10.60.7
Mg content in liver0.80.84.00.72.00.80.60.61.0-0.01.30.5-0.10.5
Mn content in liver0.70.85.80.62.4-0.0-0.2-0.20.4-1.40.5-0.2-0.20.1
Na content in liver0.40.41.10.50.60.70.50.50.5-0.40.40.4-0.9-1.0
Rb content in liver0.30.30.8-0.3-0.5-0.5-0.6-0.6-0.60.5-0.3-0.50.60.9
Se content in liver2.42.89.71.73.11.51.51.52.00.22.01.60.50.9
Sr content in liver0.50.41.70.2-0.7-0.2-0.1-0.1-0.11.0-0.30.01.21.3
Zn content in liver0.91.01.90.81.20.80.80.81.10.91.10.81.01.4
Bone: minimum diameter0.50.81.9-0.7-0.0-1.4-1.1-1.1-0.8-1.3-1.0-1.00.10.0
Time in familiar zone, hab. session 10.40.40.80.6-0.20.80.60.60.40.90.30.70.60.4
Time in novel zone, hab. session 10.20.20.70.10.2-0.2-0.4-0.4-0.3-0.8-0.3-0.6-0.4-0.5
Total zone transitions, hab. session 12.83.86.41.91.42.32.52.52.31.22.32.5-0.2-0.3
Total locomotion distance, hab. session 12.43.45.71.91.72.22.32.32.10.82.22.4-0.2-0.3
Locomotion velocity, hab. session 12.53.56.81.81.72.02.42.42.20.82.12.6-0.0-0.2
Time in familiar zone, hab. session 20.60.73.5-1.00.4-0.30.00.0-0.1-0.60.70.1-1.9-1.2
Time in novel zone, hab. session 20.90.94.30.7-0.9-0.1-0.4-0.4-0.30.8-1.0-0.42.11.5
Total zone transitions, hab. session 20.81.02.50.30.80.91.01.00.9-0.61.00.9-1.5-1.6
Total locomotion distance, hab. session 21.82.33.80.71.51.41.81.81.6-0.12.01.8-1.6-1.4
Locomotion velocity, hab. session 22.33.15.11.01.91.82.12.11.90.02.32.1-1.5-1.3
Novel to familiar place preference ratio0.30.30.90.6-0.30.50.50.50.40.6-0.10.60.90.4
Novelty place preference0.20.30.80.6-0.10.50.50.50.50.5-0.00.60.90.4
Time in novel zone, NPP test0.20.20.70.4-0.10.40.30.30.30.4-0.20.30.90.4
Total zone transitions, NPP test1.82.63.91.41.72.02.02.02.00.82.01.9-0.00.1
Total locomotion distance, NPP test1.21.62.91.10.71.41.51.51.31.31.41.70.50.6
Locomotion velocity, NPP test1.42.03.81.10.81.71.81.81.51.41.71.90.10.3
Intraocular pressure0.20.30.8-0.3-0.3-0.7-0.5-0.5-0.3-0.7-0.9-0.40.1-0.4
Delta distance traveled before/after self-admin0.20.31.20.1-0.2-0.5-0.0-0.0-0.10.7-0.0-0.20.81.1
Delta ambulatory time before/after self-admin0.10.20.5-0.5-0.2-0.7-0.3-0.3-0.30.2-0.1-0.50.40.7
Parametrial fat weight4.210.012.6-2.8-2.7-3.4-3.5-3.5-3.4-3.1-3.3-3.4-2.3-2.9
Pavlov. Cond. lever latency4.75.910.6-3.2-2.8-2.7-2.5-2.5-2.9-1.1-2.0-2.7-1.9-1.4
Pavlov. Cond. magazine entry latency2.22.96.71.92.61.91.71.72.10.51.71.51.01.1
Pavlov. Cond. change in total contacts0.80.93.21.81.11.10.70.71.1-0.10.30.61.00.4
Pavlov. Cond. index score3.74.77.92.82.82.42.22.22.60.81.82.21.71.3
Pavlov. Cond. latency score3.44.37.62.72.82.22.12.12.50.61.72.21.61.2
Pavlov. Cond. lever contacts3.33.97.52.72.22.12.02.02.30.91.52.21.81.3
Pavlov. Cond. magazine entry number2.32.96.0-1.8-2.5-2.0-1.8-1.8-2.1-0.7-1.9-1.6-0.8-1.0
Pavlov. Cond. intertrial magazine entries0.60.83.4-0.2-1.9-0.2-0.4-0.4-0.61.3-0.7-0.31.11.0
Pavlov. Cond. lever-magazine prob. diff.4.05.08.42.92.82.52.32.32.70.91.82.31.81.3
Pavlov. Cond. response bias3.64.48.52.52.92.42.22.22.60.82.12.01.31.3
Pavlov. Cond. lever latency1.62.24.8-1.4-0.9-1.6-1.3-1.3-1.3-2.2-1.4-1.2-1.4-1.9
Pavlov. Cond. magazine entry latency0.30.41.0-0.1-0.2-0.6-0.7-0.7-0.50.1-0.6-0.70.91.0
Pavlov. Cond. change in total contacts0.50.82.20.50.40.70.60.60.71.50.80.61.01.5
Pavlov. Cond. index score0.60.82.60.90.50.60.40.40.61.20.50.41.31.6
Pavlov. Cond. latency score0.40.51.80.70.50.50.20.20.41.00.40.31.11.3
Pavlov. Cond. lever contacts1.31.84.41.20.61.41.21.21.22.11.21.11.41.7
Pavlov. Cond. magazine entry number0.30.30.60.40.60.60.60.60.6-0.40.50.5-0.6-0.8
Pavlov. Cond. intertrial magazine entries0.50.82.9-0.41.4-0.00.00.00.2-1.30.9-0.2-1.7-1.1
Pavlov. Cond. lever-magazine prob. diff.0.40.62.20.80.40.50.30.30.41.10.40.31.21.5
Pavlov. Cond. response bias1.21.63.91.30.81.20.90.91.11.80.90.91.72.0
Time in closed arm before self-admin0.10.10.6-0.20.10.30.30.30.10.60.30.10.40.8
Time in closed arm after self-admin1.01.02.41.5-0.40.90.90.90.71.50.30.81.41.1
Time in open arm before self-admin0.70.71.81.40.70.70.90.91.00.50.71.00.60.3
Time in open arm after self-admin0.20.21.00.21.00.20.30.30.5-0.00.70.5-0.00.3
Bone: periosteal estimation0.71.53.3-1.1-0.2-1.7-1.4-1.4-1.0-1.8-1.4-1.1-0.1-0.4
Bone: periosteal perimeter0.30.61.2-0.7-0.0-1.0-1.0-1.0-0.7-1.1-0.7-0.8-0.4-0.4
Bone: post-yield work0.20.31.3-0.40.1-1.0-0.2-0.2-0.1-0.3-0.50.11.10.9
Progressive ratio test 1 active lever presses0.70.93.92.0-0.40.4-0.1-0.10.71.30.1-0.01.41.2
Progressive ratio test 1 breakpoint0.81.04.32.1-0.30.50.10.10.81.40.20.11.41.3
Progressive ratio test 1 inactive lever presses0.30.50.80.5-0.9-0.7-0.7-0.7-0.5-0.3-0.8-0.9-0.3-0.8
Progressive ratio test 2 active lever presses0.30.42.41.5-0.20.50.10.10.60.70.20.20.60.4
Progressive ratio test 2 breakpoint0.40.52.81.7-0.20.50.20.20.60.80.30.30.70.5
Progressive ratio test 2 inactive lever presses0.50.83.01.70.50.80.50.51.00.80.40.51.10.9
Incentive Sensitization - Responses0.50.71.51.20.90.60.80.81.10.41.10.9-0.2-0.3
Incentive Sensitization - Breakpoint0.30.41.11.00.70.40.60.60.90.10.80.7-0.4-0.5
Sum of active levers in priming session hrs 5-60.40.30.70.80.30.20.70.70.60.50.40.60.70.6
Progressive ratio3.45.37.8-2.2-1.9-2.1-2.7-2.7-2.5-2.2-2.3-2.8-1.8-2.0
Food seeking constrained by brief footshock0.50.61.90.6-1.10.10.40.4-0.01.4-0.10.11.21.3
Seeking ratio, punishment vs. effort3.14.46.02.11.22.12.52.52.22.21.92.41.91.9
Retroperitoneal fat weight0.52.33.9-1.0-1.2-1.3-2.0-2.0-1.4-1.6-1.8-1.7-1.0-1.4
Reaction time number correct0.81.63.1-1.6-1.8-1.0-1.1-1.1-1.5-0.7-1.2-1.1-1.2-1.3
Reaction time mean minus median0.20.42.00.21.4-0.6-0.3-0.30.2-1.0-0.1-0.30.50.5
Reaction time mean minus median AUC0.20.62.40.61.0-0.5-0.3-0.30.1-0.1-0.2-0.31.51.6
Reaction time num false alarms0.40.62.60.41.60.10.20.20.7-1.10.60.4-0.9-0.8
Reaction time num false alarms AUC0.61.04.00.72.00.60.70.71.2-0.71.10.9-0.8-0.5
Reaction time trials correct on left0.81.63.1-1.6-1.8-1.0-1.1-1.1-1.5-0.7-1.2-1.1-1.2-1.3
Reaction time trials on left0.91.73.1-1.7-1.8-1.1-1.2-1.2-1.5-0.7-1.3-1.1-1.1-1.2
Reaction time mean0.30.51.6-0.00.4-1.0-0.5-0.5-0.3-0.2-0.5-0.41.31.3
Reaction time mean AUC0.40.61.5-0.20.0-1.2-0.7-0.7-0.6-0.3-0.8-0.61.21.2
Median of all reaction times0.30.51.4-0.2-0.2-1.0-0.5-0.5-0.50.1-0.6-0.41.21.2
Reaction time omissions0.50.82.3-0.90.7-1.0-0.8-0.8-0.6-1.5-0.4-0.9-1.0-0.7
Reaction time false alarm rate1.82.48.31.72.91.31.41.42.0-0.11.81.60.10.3
Reaction time premature initiation rate0.00.00.10.3-0.0-0.20.10.1-0.10.30.1-0.00.00.1
Reaction time premature initiations0.30.61.5-0.7-1.2-0.9-0.7-0.7-1.1-0.1-0.8-0.8-0.6-0.6
Std. dev. reaction times0.30.52.00.41.4-0.6-0.2-0.20.3-0.40.0-0.11.11.3
Reaction time trials completed0.91.73.1-1.7-1.8-1.1-1.2-1.2-1.5-0.7-1.3-1.1-1.1-1.2
Reaction time trials AUC1.01.83.3-1.8-1.8-1.1-1.2-1.2-1.6-0.7-1.3-1.2-1.2-1.3
Run reversals in cocaine runway, females0.90.93.91.1-0.50.30.10.10.51.4-0.20.42.01.5
Run reversals in cocaine runway, males0.40.41.60.81.30.50.40.40.7-0.80.10.30.70.3
Latency to leave start box in cocaine runway0.60.71.21.00.60.71.11.10.80.91.01.10.30.4
Latency to leave start box in cocaine runway, F0.40.51.00.70.50.50.80.80.60.80.81.00.40.5
Latency to leave start box in cocaine runway, M0.10.10.30.50.00.40.50.50.30.10.30.3-0.1-0.2
Std. dev. time between licks in bursts1.31.77.91.52.81.10.80.81.4-1.41.01.0-0.5-0.6
Total sessions with >9 infusions0.60.73.21.80.20.40.30.30.90.90.30.41.21.0
Short access day 1 total inactive lever presses0.50.62.41.20.50.20.40.40.90.30.00.41.61.1
Short access day 10 total inactive lever presses1.12.810.3-2.20.9-0.8-0.5-0.5-0.6-2.10.4-0.6-3.2-2.9
Short access day 1 total infusions1.21.65.22.30.80.70.70.71.41.30.70.91.81.5
Short access day 10 total infusions0.10.21.11.10.0-0.10.00.00.40.50.10.10.60.5
Short access total infusions0.91.14.62.1-0.10.40.40.40.91.20.20.51.71.3
Short access day 1 locomotion0.20.20.60.40.80.2-0.2-0.20.6-0.30.6-0.0-0.7-0.6
Short access day 10 total locomotion0.40.71.8-1.00.8-0.7-0.9-0.9-0.1-1.00.2-0.8-1.3-0.9
Short access total locomotion0.20.30.6-0.40.1-0.6-0.8-0.8-0.1-0.4-0.1-0.7-0.5-0.2
One hour access (0.3 mA shock)2.22.53.91.91.91.42.02.01.60.91.91.90.40.4
Compulsive drug intake0.70.82.4-1.01.5-0.31.01.00.4-0.31.31.0-0.7-0.2
One hour access (shock baseline)0.81.24.82.20.11.20.70.71.01.20.30.61.41.2
Social response proportion0.10.10.20.20.4-0.00.10.10.1-0.00.10.20.40.4
Social responses0.20.20.9-0.60.3-0.3-0.2-0.2-0.2-0.60.2-0.2-0.9-0.7
Social time1.21.65.2-0.81.9-0.8-0.2-0.20.1-2.30.6-0.2-2.1-1.7
Soleus weight0.41.17.10.72.7-0.2-0.3-0.30.5-1.70.1-0.10.60.6
Bone: stiffness0.60.91.5-1.2-1.2-1.2-0.8-0.8-0.8-1.0-1.1-0.6-0.5-1.0
Tibialis anterior weight0.10.20.9-0.10.50.30.50.50.30.61.00.5-0.40.1
Time to tail flick, vehicle, before self-admin5.15.311.7-3.0-0.2-1.8-1.8-1.8-1.9-3.4-1.3-1.6-3.2-3.2
Time to tail flick, vehicle, after self-admin0.10.10.40.60.1-0.20.30.30.20.50.60.30.20.4
Time to tail flick, test, before self-admin0.50.52.60.00.60.30.20.20.2-0.50.60.2-1.6-1.5
Time to tail flick, test, after self-admin0.10.10.30.40.50.60.10.10.5-0.30.40.2-0.4-0.3
Delta time to tail flick, vehicle, before/after SA4.94.711.92.8-0.31.41.71.71.63.51.31.62.93.0
Delta time to tail flick, test, before/after SA0.30.30.6-0.8-0.8-0.3-0.7-0.7-0.6-0.4-0.7-0.70.20.0
Tibia length1.84.811.1-2.2-0.6-2.6-2.4-2.4-2.0-3.3-2.3-2.3-1.1-1.5
Ambulatory time before self-admin0.40.51.6-0.50.3-0.6-0.4-0.4-0.3-1.2-0.3-0.5-1.2-1.3
Ambulatory time after self-admin0.70.91.8-1.20.1-1.4-0.8-0.8-0.7-1.2-0.5-1.1-1.0-0.8
Bone: tissue strength0.20.20.8-0.2-0.9-0.3-0.2-0.2-0.30.7-0.5-0.10.70.7
Total heroin consumption0.50.51.9-1.10.4-0.8-0.1-0.1-0.4-0.90.3-0.1-1.4-1.0
Bone: trabecular number0.30.51.40.6-0.00.50.70.70.61.20.70.60.70.9
Bone: trabecular spacing1.11.42.1-1.1-0.8-1.3-1.5-1.5-1.3-1.2-1.5-1.4-0.5-0.6
Bone: trabecular thickness0.20.20.4-0.1-0.6-0.5-0.4-0.4-0.3-0.1-0.7-0.40.60.3
Bone: trabecular tissue density0.30.41.01.00.90.70.60.60.8-0.00.30.70.70.4
Water consumed over 24 hours0.10.10.4-0.50.10.20.10.10.10.60.6-0.1-0.30.3
Number of responses in last shaping day4.44.811.93.51.72.21.81.82.51.91.72.12.42.0