Hub : Genes

LOC120098859

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression LOC120098859 0.16 0.08 3.5e-08 0.08 0.14 0.15 0.1 4.9e-05 1.2e-07 1.6e-08 4.9e-06
2 PL gene expression LOC120098859 0.07 0.03 1.3e-10 0.11 0.1 0.08 0.12 3.4e-12 6.6e-11 1.8e-09 1.6e-12
3 Brain gene expression LOC120098859 0.29 0.11 0.0e+00 0.21 0.14 0.19 0.2 4.1e-19 5.2e-13 4.3e-17 7.3e-19
4 NAcc gene expression LOC120098859 0.06 0.03 9.1e-07 0.05 0.04 0.05 0.04 9.0e-08 2.3e-07 1.1e-07 6.6e-07
5 IC gene expression LOC120098859 0.31 0.12 2.8e-09 0.25 0.24 0.24 0.24 8.7e-11 1.8e-10 2.0e-10 1.3e-10
6 Adipose mRNA stability LOC120098859 0.05 0.04 3.5e-03 0.03 0.01 0.02 0.02 6.0e-04 1.0e-02 2.2e-03 2.5e-03
7 Adipose gene expression LOC120098859 0.57 0.1 0.0e+00 0.47 0.46 0.48 0.48 7.9e-59 9.5e-57 2.2e-60 6.4e-60

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.00.10.20.2-0.2-0.4-0.3-0.30.1-0.2
Area under the delay curve0.10.10.40.70.30.30.3-0.20.00.2
BMI with tail2.68.810.4-2.9-3.2-3.1-3.2-3.2-2.0-3.0
BMI without tail1.33.95.6-2.4-2.2-2.0-2.0-1.9-1.4-1.9
Body weight1.66.911.6-1.4-2.5-2.5-2.4-2.7-3.4-3.0
Weight adjusted by age0.10.10.40.60.20.30.3-0.5-0.4-0.1
Bone surface0.10.10.30.50.40.20.20.4-0.30.1
Bone volume0.00.00.10.2-0.0-0.2-0.2-0.1-0.3-0.2
Breakpoint value in progressive ratio session0.40.52.7-0.2-0.5-0.3-0.20.2-1.6-0.2
Number of licking bursts0.50.81.10.90.90.90.81.00.50.8
Context. condit. distance diff. score3.03.66.42.52.01.91.92.00.81.7
Locomotion velocity, session 13.03.23.61.81.91.91.71.61.91.7
Locomotion distance, session 11.72.25.70.41.41.31.31.42.41.5
Locomotion velocity, session 20.70.91.40.81.01.01.01.20.50.9
Locomotion distance, session 20.60.91.70.61.00.80.80.81.30.9
Locomotion velocity, session 30.80.91.3-0.10.81.00.91.11.11.1
Locomotion distance, session 32.22.33.80.81.51.51.51.61.91.7
Stereotopy head waving bouts, day 30.20.30.90.40.40.50.40.5-1.00.2
Stereotopy head waving duration, day 30.30.30.50.40.60.70.70.6-0.20.5
Locomotion velocity, session 71.21.32.21.51.21.01.00.81.41.1
Locomotion distance, session 72.43.03.91.81.91.71.61.42.01.7
Stereotopy head waving bouts, day 70.20.30.40.00.30.60.60.60.60.6
Stereotopy head waving duration, day 70.00.00.1-0.3-0.10.10.10.20.10.2
Locomotion velocity, session 83.33.96.02.42.22.22.02.20.31.7
Locomotion distance, session 82.94.15.22.12.32.02.02.21.52.0
Degree of sensitization distance0.40.41.40.5-0.2-0.4-0.4-0.5-1.2-0.7
Degree of sensitization stereotypy0.50.51.50.00.50.70.70.71.20.8
Conditioned locomotion2.02.35.0-0.7-1.4-1.5-1.4-1.2-2.2-1.6
Cocaine response after cond. corrected1.01.21.7-0.8-1.1-1.3-1.2-1.1-1.0-1.2
Cocaine response after cond. not corrected0.30.40.6-0.5-0.6-0.7-0.7-0.4-0.8-0.7
Cocaine response before conditioning0.81.01.50.61.01.21.11.20.51.0
Saline control response4.25.67.0-2.6-2.6-2.5-2.4-2.4-1.6-2.3
Bone: connectivity density0.10.10.20.3-0.1-0.5-0.4-0.3-0.1-0.4
Bone: cortical apparent density1.41.93.5-1.9-1.4-1.5-1.4-1.3-0.5-1.2
Bone: cortical area0.00.00.1-0.2-0.0-0.1-0.10.00.3-0.0
Bone: cortical porosity1.92.12.71.01.41.61.51.31.51.6
Bone: cortical porosity2.22.42.91.51.61.71.61.31.41.6
Bone: cortical thickness0.71.23.7-1.9-0.8-0.9-0.9-0.71.2-0.4
Bone: cortical thickness3.64.38.4-2.9-2.1-2.2-2.2-1.9-0.5-1.8
Bone: cortical tissue density1.21.63.0-1.7-1.3-1.4-1.3-1.2-0.5-1.1
Condit. Reinf. active minus inactive responses0.20.20.50.70.50.50.40.10.70.4
Condit. Reinf. active-inactive response ratio0.80.91.3-0.7-1.0-1.0-1.0-1.2-0.6-1.0
Condit. Reinf. active responses0.10.10.30.4-0.1-0.2-0.2-0.50.2-0.2
Condit. Reinf. inactive responses0.10.10.20.2-0.1-0.3-0.3-0.40.4-0.2
Incentive salience index mean0.81.02.61.61.00.90.90.70.70.8
Condit. Reinf. lever presses1.01.54.32.11.21.01.11.10.40.9
Condit. Reinf. active minus inactive responses0.70.91.40.71.11.21.11.00.61.0
Condit. Reinf. active-inactive response ratio0.40.50.70.70.80.90.80.60.20.6
Condit. Reinf. active responses0.60.81.10.51.01.11.00.90.60.9
Condit. Reinf. inactive responses0.00.00.3-0.5-0.1-0.1-0.00.1-0.10.0
Condit. Reinf. lever presses1.21.72.70.91.31.31.31.11.61.3
Condit. Reinf. lever reinforcers received0.91.21.60.61.21.31.21.11.01.2
Conditioned reinforcement - actives0.00.10.30.50.20.00.2-0.20.10.1
Conditioned reinforcement - inactives0.30.40.80.40.50.50.80.40.90.7
Conditioned locomotion0.20.31.51.20.40.30.3-0.40.10.1
Patch foraging indifference point 0 sec2.24.05.3-2.3-2.0-2.0-2.2-2.3-0.7-2.0
Patch foraging indifference point AUC0.40.51.20.30.70.60.81.10.60.7
Delay disc. indifference point, 0s delay0.20.30.70.80.60.60.40.10.10.3
Delay disc. indifference point, 16s delay0.10.10.50.00.20.30.3-0.10.70.3
Delay disc. indifference point, 2s delay0.50.51.41.20.80.80.80.20.40.5
Delay disc. indifference point, 24s delay0.10.10.20.30.20.30.3-0.50.50.2
Delay disc. indifference point, 4s delay0.10.10.40.2-0.1-0.0-0.0-0.2-0.7-0.2
Delay disc. indifference point, 8s delay0.10.10.40.60.10.10.1-0.4-0.1-0.0
Indifference point function ln k0.50.81.30.71.01.10.90.90.60.9
Indifference point function log k0.50.81.30.71.01.10.90.90.60.9
Patch foraging total patch changes 0 sec2.13.95.6-2.4-2.0-2.0-2.2-2.3-0.5-1.9
Patch foraging total patch changes 12 sec0.70.93.2-1.8-0.9-1.0-0.9-0.60.1-0.7
Patch foraging total patch changes 18 sec3.75.68.1-2.9-2.4-2.6-2.6-2.4-0.8-2.3
Patch foraging total patch changes 24 sec1.22.03.1-1.8-1.3-1.5-1.6-1.70.4-1.3
Patch foraging total patch changes 6 sec1.82.74.6-2.1-1.6-1.7-1.7-1.90.2-1.4
Patch foraging time to switch 0 sec2.14.45.0-1.9-2.2-2.2-2.2-2.2-1.9-2.1
Patch foraging water rate 0 sec0.00.10.60.10.20.00.0-0.10.80.1
Patch foraging water rate 12 sec0.20.31.7-0.60.1-0.0-0.00.11.30.3
Patch foraging water rate 18 sec0.20.30.5-0.2-0.6-0.6-0.6-0.7-0.2-0.6
Patch foraging water rate 24 sec0.20.20.5-0.50.40.30.20.50.70.4
Patch foraging water rate 6 sec0.10.20.8-0.60.1-0.10.00.30.90.3
Seeking ratio, delayed vs. immediate footshock0.40.51.8-1.3-0.6-0.5-0.50.2-0.9-0.5
Distance traveled before self-admin0.30.31.5-0.3-0.5-0.5-0.30.3-1.2-0.3
Distance traveled after self-admin0.81.03.0-1.0-0.9-0.9-0.7-0.1-1.7-0.8
Extensor digitorum longus weight0.31.42.61.61.31.21.21.20.21.0
Bone: elastic displacement0.60.72.40.30.70.80.80.41.60.9
Bone: elastic work0.00.10.3-0.1-0.00.0-0.0-0.30.50.1
Bone: endosteal estimation0.71.68.61.2-0.4-0.3-0.3-0.4-2.9-1.0
Bone: endosteal perimeter0.40.94.31.3-0.00.0-0.00.0-2.1-0.5
Epididymis fat weight7.525.642.4-6.5-5.3-5.3-5.5-5.2-1.0-4.6
Delta time in closed arm before/after self-admin0.20.20.4-0.4-0.5-0.3-0.3-0.6-0.4-0.3
Delta time in open arm before/after self-admin0.10.10.20.50.10.00.20.2-0.20.1
Diff in mean of infusions in LGA sessions0.00.00.20.1-0.2-0.2-0.10.1-0.4-0.0
Delay discount exponential model param0.10.20.5-0.7-0.4-0.4-0.40.1-0.1-0.3
Extinction: sum of active levers before priming0.10.10.10.20.20.30.20.40.10.2
Active lever presses in extinction session 60.20.20.80.2-0.4-0.4-0.2-0.90.1-0.3
Bone: final force4.06.47.3-2.3-2.6-2.6-2.7-2.6-2.2-2.7
Bone: final moment2.54.04.8-1.6-2.0-2.0-2.1-2.2-1.8-2.1
Food consumed during 24 hour testing period2.23.05.8-0.9-1.7-1.7-1.6-1.6-2.4-1.8
Glucose3.65.610.73.32.42.42.52.21.12.1
Heart weight1.01.54.20.71.21.21.30.62.01.2
Delay discount hyperbolic model param0.20.30.6-0.8-0.5-0.5-0.6-0.1-0.3-0.5
Intermittent access intake day 1-15 change0.30.62.2-0.8-0.8-0.5-0.6-0.1-1.5-0.6
Intermittent access intake escalation0.51.02.4-1.1-1.1-0.8-0.9-0.5-1.5-0.9
Intermittent access intake escalation 20.20.20.50.70.20.40.40.3-0.70.1
Intermitt. access day 1 inactive lever presses0.10.41.8-0.60.40.40.41.30.20.6
Intermitt. access day 15 inactive lever presses0.10.30.6-0.6-0.5-0.5-0.4-0.2-0.8-0.5
Intermitt. access escalation Index0.10.21.0-0.30.30.30.11.00.10.4
Intermittent access day 1 total infusions1.42.24.42.11.41.31.50.51.71.4
Intermittent access day 15 total infusions0.00.10.20.40.10.10.2-0.10.20.2
Intermittent access terminal intake (last 3 days)0.20.20.40.60.40.50.60.10.60.5
Intermittent access total infusions0.50.61.21.10.70.70.80.10.90.7
Intermittent access day 1 locomotion0.10.10.30.50.1-0.10.0-0.40.3-0.0
Intermittent access day 15 total locomotion0.40.82.10.0-0.8-0.7-0.6-1.0-1.4-0.9
Intermittent access total locomotion0.20.30.70.5-0.4-0.5-0.3-0.8-0.4-0.5
Intermittent access standard deviation1.42.84.0-2.0-1.8-1.7-1.5-1.3-1.9-1.5
Left kidney weight1.15.26.5-1.8-2.2-2.2-2.2-2.3-2.6-2.6
Right kidney weight1.56.711.7-1.6-2.4-2.5-2.5-2.5-3.4-2.9
Cocaine induced anxiety0.10.10.2-0.2-0.2-0.5-0.20.4-0.3-0.2
Post-drug Anxiety0.70.71.5-0.7-0.9-1.2-0.9-0.6-0.5-0.9
Baseline Anxiety0.80.91.7-0.9-0.9-0.9-1.1-1.3-0.5-0.9
Tail length0.31.42.01.41.01.11.41.3-1.00.8
Length with tail0.31.14.61.60.40.40.60.3-2.2-0.3
Length without tail0.82.76.70.2-1.2-1.3-1.3-1.8-2.6-2.0
Times rat made contact with spout0.20.20.9-0.7-0.2-0.2-0.2-0.31.00.1
Lifetime Intake0.30.41.01.00.50.60.7-0.10.70.5
Liver weight, left0.61.04.20.4-0.6-0.7-0.7-0.5-2.0-1.1
Liver weight, right0.91.53.71.90.90.91.11.1-1.60.5
Locomotor activity0.10.10.4-0.7-0.10.10.00.6-0.40.1
Locomotor testing distance0.30.51.7-1.3-0.7-0.6-0.7-0.2-0.6-0.5
Locomotor testing rearing0.71.52.6-1.3-1.1-1.1-1.3-0.8-1.6-1.3
Locomotion in novel chamber0.20.30.50.50.40.40.70.70.10.7
Locomotion in novel chamber post-restriction0.91.51.8-1.2-1.3-1.3-1.2-1.2-1.1-1.2
Fecal boli incidents, locomotor time 10.20.30.70.6-0.4-0.5-0.4-0.8-0.5-0.6
Change in fecal boli incidents, locomotor task0.30.30.8-0.9-0.5-0.4-0.5-0.2-0.5-0.4
Time >=10cm from walls, locomotor time 14.34.68.2-1.4-2.2-2.2-2.1-1.7-2.9-2.3
Bouts of movement, locomotor time 10.10.10.40.20.10.20.10.6-0.40.1
Total resting periods, locomotor time 10.10.10.20.40.10.10.10.5-0.50.0
Rest time, locomotor task time 11.21.52.01.41.41.21.21.21.01.1
Distance moved, locomotor task time 10.91.41.9-1.4-1.3-1.1-1.1-1.1-1.1-1.1
Vertical activity count, locomotor time 12.45.77.2-2.2-2.5-2.3-2.3-2.3-2.7-2.4
Time >=10cm from walls, locomotor time 21.82.74.3-0.7-1.7-1.6-1.5-1.9-2.1-1.8
Bouts of movement, locomotor time 20.20.31.00.40.30.50.51.0-0.60.4
Total resting periods, locomotor time 20.61.12.60.90.91.11.11.6-0.20.9
Rest time, locomotor task time 20.50.71.61.00.80.80.71.2-0.30.6
Distance moved, locomotor task time 22.83.46.7-1.3-1.9-1.8-1.8-2.6-1.2-1.9
Vertical activity count, locomotor time 22.12.95.7-1.0-1.6-1.6-1.7-2.4-1.2-1.8
Light reinforcement 12.56.17.3-2.7-2.4-2.5-2.7-2.0-2.4-2.5
Light reinforcement 22.03.16.2-1.1-1.6-1.7-1.8-1.5-2.5-2.0
Bone: marrow area0.81.89.31.1-0.5-0.4-0.4-0.5-3.0-1.1
Bone: maximum diameter0.81.43.31.81.31.21.11.2-0.10.8
Bone: maximum force0.81.41.7-1.0-1.2-1.2-1.3-1.3-1.0-1.3
Bone: maximum moment0.30.50.8-0.3-0.6-0.6-0.7-0.9-0.6-0.8
Mean time between licks in bursts2.66.38.32.52.82.72.82.90.92.5
Mean num. licks in bursts0.40.61.3-1.2-0.8-0.8-0.7-0.90.3-0.5
Cd content in liver1.41.63.2-0.4-1.1-1.4-1.3-1.8-1.0-1.4
Co content in liver4.75.57.8-1.8-2.5-2.5-2.5-2.8-1.6-2.5
Cu content in liver0.30.31.3-0.9-0.1-0.00.00.21.10.4
Fe content in liver0.50.71.1-0.7-0.7-0.7-0.9-1.0-0.8-0.8
K content in liver1.61.51.81.01.31.21.21.31.31.2
Mg content in liver1.21.22.01.11.31.01.01.40.81.0
Mn content in liver2.22.44.62.11.81.61.51.70.01.2
Na content in liver0.30.30.6-0.60.30.40.40.80.70.6
Rb content in liver0.50.51.00.2-0.6-0.8-0.8-1.0-0.4-0.9
Se content in liver5.66.68.32.32.92.92.72.81.52.6
Sr content in liver0.10.10.40.6-0.0-0.1-0.1-0.5-0.2-0.2
Zn content in liver1.01.11.71.11.31.11.10.90.70.9
Bone: minimum diameter0.20.52.00.8-0.2-0.3-0.3-0.3-1.4-0.6
Time in familiar zone, hab. session 10.10.10.70.10.10.00.0-0.20.80.1
Time in novel zone, hab. session 10.10.10.2-0.00.20.30.30.4-0.20.2
Total zone transitions, hab. session 11.52.05.50.11.21.21.21.52.31.5
Total locomotion distance, hab. session 11.62.24.80.31.41.31.31.62.21.6
Locomotion velocity, hab. session 11.52.14.20.21.41.31.31.62.01.5
Time in familiar zone, hab. session 20.20.21.1-1.1-0.2-0.2-0.20.4-0.3-0.1
Time in novel zone, hab. session 20.20.20.90.7-0.2-0.2-0.3-0.9-0.1-0.4
Total zone transitions, hab. session 20.20.30.8-0.60.30.20.30.80.90.5
Total locomotion distance, hab. session 20.70.92.1-0.30.80.70.71.31.51.0
Locomotion velocity, hab. session 21.31.73.10.01.31.11.11.71.81.5
Novel to familiar place preference ratio0.00.00.20.0-0.1-0.1-0.0-0.30.40.1
Novelty place preference0.00.00.20.10.00.00.1-0.10.50.2
Time in novel zone, NPP test0.00.00.10.20.0-0.00.1-0.10.40.2
Total zone transitions, NPP test1.52.14.00.81.51.31.31.52.01.5
Total locomotion distance, NPP test0.40.52.10.40.70.50.30.31.50.5
Locomotion velocity, NPP test0.40.62.80.30.70.50.40.41.70.6
Intraocular pressure0.30.40.7-0.2-0.6-0.8-0.8-0.8-0.4-0.8
Delta distance traveled before/after self-admin0.10.10.1-0.3-0.3-0.1-0.1-0.3-0.4-0.2
Delta ambulatory time before/after self-admin0.20.20.4-0.5-0.5-0.4-0.4-0.4-0.6-0.5
Parametrial fat weight3.78.810.6-2.3-3.1-3.1-3.0-2.7-3.3-3.1
Pavlov. Cond. lever latency7.49.311.8-3.4-3.2-3.2-3.1-2.8-2.6-3.0
Pavlov. Cond. magazine entry latency4.65.96.82.62.62.62.52.51.92.4
Pavlov. Cond. change in total contacts1.71.82.41.51.41.51.41.31.11.3
Pavlov. Cond. index score6.78.410.63.33.13.13.02.82.32.8
Pavlov. Cond. latency score6.38.010.33.23.03.02.92.72.22.8
Pavlov. Cond. lever contacts5.46.49.23.02.72.62.52.32.12.4
Pavlov. Cond. magazine entry number3.84.95.3-2.2-2.3-2.3-2.2-2.2-2.0-2.2
Pavlov. Cond. intertrial magazine entries1.51.82.7-1.4-1.4-1.5-1.4-1.7-0.2-1.2
Pavlov. Cond. lever-magazine prob. diff.6.88.510.43.23.13.12.92.72.42.8
Pavlov. Cond. response bias6.37.78.72.93.02.92.82.72.32.7
Pavlov. Cond. lever latency0.70.92.6-0.4-0.9-0.9-0.9-0.7-1.6-1.0
Pavlov. Cond. magazine entry latency0.30.31.61.20.30.30.30.0-0.60.1
Pavlov. Cond. change in total contacts0.20.30.50.30.50.60.60.30.70.5
Pavlov. Cond. index score0.50.61.11.10.80.80.80.50.60.7
Pavlov. Cond. latency score0.40.50.91.00.70.80.80.50.50.6
Pavlov. Cond. lever contacts0.40.52.00.20.60.60.60.41.40.7
Pavlov. Cond. magazine entry number0.10.20.3-0.50.30.20.20.50.60.4
Pavlov. Cond. intertrial magazine entries0.61.02.60.41.00.91.01.6-0.01.0
Pavlov. Cond. lever-magazine prob. diff.0.30.40.90.90.60.70.70.40.50.6
Pavlov. Cond. response bias0.60.81.50.90.90.90.90.61.20.8
Time in closed arm before self-admin0.00.10.20.50.30.20.20.00.10.1
Time in closed arm after self-admin0.30.31.00.40.50.60.4-0.01.00.5
Time in open arm before self-admin0.70.81.10.70.80.91.00.90.81.1
Time in open arm after self-admin0.30.30.50.70.40.40.70.70.00.6
Bone: periosteal estimation0.30.52.90.5-0.3-0.2-0.3-0.2-1.7-0.6
Bone: periosteal perimeter0.10.21.00.4-0.2-0.2-0.3-0.2-1.0-0.5
Bone: post-yield work0.30.41.71.30.30.30.30.2-0.9-0.1
Progressive ratio test 1 active lever presses0.20.20.60.80.40.50.5-0.10.40.4
Progressive ratio test 1 breakpoint0.20.30.60.80.50.50.6-0.10.50.5
Progressive ratio test 1 inactive lever presses0.71.01.3-1.0-1.1-1.1-1.0-1.1-0.6-1.0
Progressive ratio test 2 active lever presses0.30.30.60.70.50.60.70.40.50.6
Progressive ratio test 2 breakpoint0.30.40.60.80.60.60.70.40.50.7
Progressive ratio test 2 inactive lever presses0.60.91.91.41.00.91.00.60.90.9
Incentive Sensitization - Responses0.60.81.50.60.90.91.01.20.61.0
Incentive Sensitization - Breakpoint0.40.51.10.50.70.70.81.10.40.8
Sum of active levers in priming session hrs 5-60.20.20.40.60.30.30.60.40.40.6
Progressive ratio2.54.05.8-2.4-2.1-1.9-1.9-1.5-2.2-1.9
Food seeking constrained by brief footshock0.10.10.30.3-0.10.1-0.1-0.60.3-0.1
Seeking ratio, punishment vs. effort2.33.34.91.91.81.81.71.22.21.8
Retroperitoneal fat weight0.21.11.3-0.6-1.0-1.0-1.1-1.1-1.1-1.2
Reaction time number correct0.81.52.9-1.7-1.4-1.3-1.2-1.0-0.9-1.0
Reaction time mean minus median0.71.86.32.51.31.31.21.0-0.50.7
Reaction time mean minus median AUC1.02.58.83.01.51.51.40.9-0.30.9
Reaction time num false alarms0.10.20.7-0.10.50.40.40.80.10.4
Reaction time num false alarms AUC0.30.51.5-0.10.80.70.71.20.50.7
Reaction time trials correct on left0.81.52.9-1.7-1.4-1.3-1.2-1.0-0.9-1.0
Reaction time trials on left0.81.52.7-1.6-1.4-1.3-1.2-1.0-1.0-1.0
Reaction time mean0.61.05.42.30.70.60.40.1-0.9-0.0
Reaction time mean AUC0.71.15.52.30.60.50.4-0.0-1.1-0.1
Median of all reaction times0.40.62.91.70.20.20.0-0.4-0.9-0.3
Reaction time omissions0.30.41.31.10.40.30.30.5-0.9-0.0
Reaction time false alarm rate1.62.23.31.01.71.51.51.81.21.4
Reaction time premature initiation rate0.20.20.4-0.4-0.3-0.4-0.6-0.7-0.2-0.6
Reaction time premature initiations1.01.72.2-1.5-1.3-1.2-1.4-1.4-0.9-1.3
Std. dev. reaction times1.12.17.72.81.41.41.21.0-0.50.7
Reaction time trials completed0.81.52.7-1.6-1.4-1.3-1.2-1.0-1.0-1.0
Reaction time trials AUC0.91.82.9-1.7-1.5-1.4-1.3-1.1-1.0-1.1
Run reversals in cocaine runway, females0.10.10.40.20.00.20.1-0.60.60.1
Run reversals in cocaine runway, males1.61.62.81.71.31.31.31.30.61.1
Latency to leave start box in cocaine runway0.20.20.60.20.50.50.10.20.80.3
Latency to leave start box in cocaine runway, F0.10.10.40.30.40.4-0.0-0.10.60.1
Latency to leave start box in cocaine runway, M0.00.00.1-0.00.10.10.10.20.30.2
Std. dev. time between licks in bursts4.35.87.62.42.72.62.62.71.12.4
Total sessions with >9 infusions0.20.20.40.60.40.50.60.20.40.5
Short access day 1 total inactive lever presses1.11.53.21.81.31.41.30.70.61.0
Short access day 10 total inactive lever presses0.30.82.8-1.7-0.7-0.7-0.80.6-0.7-0.5
Short access day 1 total infusions0.81.01.51.21.01.11.10.50.91.0
Short access day 10 total infusions0.00.00.10.2-0.00.00.20.00.00.2
Short access total infusions0.30.30.80.90.50.50.70.00.50.5
Short access day 1 locomotion0.30.41.10.10.40.50.71.00.30.7
Short access day 10 total locomotion0.10.10.3-0.5-0.2-0.20.00.6-0.6-0.0
Short access total locomotion0.00.00.2-0.2-0.2-0.3-0.10.1-0.4-0.1
One hour access (0.3 mA shock)2.02.33.21.11.51.51.61.81.31.7
Compulsive drug intake0.50.62.00.40.70.80.71.4-0.20.8
One hour access (shock baseline)0.40.61.21.10.70.60.70.01.10.6
Social response proportion0.00.00.1-0.2-0.1-0.1-0.2-0.2-0.2-0.3
Social responses0.10.10.4-0.7-0.1-0.0-0.10.3-0.6-0.1
Social time0.60.92.90.50.80.80.71.7-0.80.6
Soleus weight1.64.88.93.02.42.22.42.2-0.11.8
Bone: stiffness1.52.43.0-1.6-1.5-1.6-1.7-1.4-1.2-1.7
Tibialis anterior weight0.00.10.4-0.6-0.1-0.2-0.10.00.20.0
Time to tail flick, vehicle, before self-admin1.21.22.2-1.2-0.9-1.0-1.3-0.2-1.5-1.2
Time to tail flick, vehicle, after self-admin0.00.10.30.60.1-0.00.20.2-0.30.1
Time to tail flick, test, before self-admin0.20.20.7-0.50.10.10.30.90.40.5
Time to tail flick, test, after self-admin1.71.82.51.31.31.31.51.60.91.4
Delta time to tail flick, vehicle, before/after SA0.80.71.61.30.50.50.8-0.11.30.7
Delta time to tail flick, test, before/after SA0.00.00.10.2-0.00.1-0.1-0.3-0.1-0.2
Tibia length0.41.27.00.1-0.5-0.4-0.5-0.0-2.7-0.9
Ambulatory time before self-admin0.10.10.40.00.00.10.30.6-0.60.2
Ambulatory time after self-admin0.30.41.6-0.6-0.5-0.4-0.30.1-1.3-0.4
Bone: tissue strength0.10.10.40.3-0.3-0.3-0.3-0.6-0.3-0.4
Total heroin consumption0.20.20.8-0.5-0.3-0.2-0.00.6-0.90.0
Bone: trabecular number0.00.10.20.0-0.0-0.3-0.2-0.20.5-0.1
Bone: trabecular spacing0.40.51.7-0.5-0.7-0.4-0.3-0.6-1.3-0.6
Bone: trabecular thickness0.30.40.60.2-0.5-0.7-0.8-0.7-0.5-0.7
Bone: trabecular tissue density0.91.31.81.11.11.41.31.10.71.2
Water consumed over 24 hours0.00.00.00.20.10.0-0.1-0.10.2-0.1
Number of responses in last shaping day5.25.77.52.12.52.72.71.82.22.5