Hub : Genes

LOC120098270

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Brain	gene expression	LOC120098270	0.37	0.2	2.9e-12	0.14	0.1	0.12	0.12	3.5e-13	7.4e-10	1.6e-11	2.1e-11
2	BLA	gene expression	LOC120098270	0.07	0.07	4.1e-03	0.04	0.02	0.03	0.04	4.4e-03	3.5e-02	8.9e-03	2.1e-03
3	PL	gene expression	LOC120098270	0.07	0.07	1.1e-05	0.04	0.04	0.04	0.04	2.0e-05	1.7e-05	1.6e-05	2.7e-05
4	Liver	gene expression	LOC120098270	0.18	0.14	5.9e-05	0.03	0.03	0.05	0.03	2.9e-04	1.3e-04	4.5e-06	2.1e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
Bone: apparent density	0.6	1.0	1.8	-0.4	1.1	-0.8	-1.4
Area under the delay curve	0.4	0.4	1.2	-1.1	0.3	-0.4	0.4
BMI with tail	0.8	2.4	4.4	1.2	-2.1	1.7	1.0
BMI without tail	1.7	3.4	5.2	1.4	-2.3	2.1	1.4
Body weight	1.1	4.4	6.0	2.5	-2.3	2.4	0.9
Weight adjusted by age	0.8	0.9	1.4	1.2	-0.8	1.0	0.8
Bone surface	0.3	0.5	1.6	1.3	0.3	0.2	-0.6
Bone volume	0.4	0.7	1.3	0.8	0.8	-0.3	-1.1
Breakpoint value in progressive ratio session	2.3	2.5	4.5	-2.1	1.5	-1.5	0.9
Number of licking bursts	1.8	2.1	3.4	1.4	-1.8	1.7	0.6
Context. condit. distance diff. score	0.1	0.1	0.2	0.4	0.1	0.2	-0.2
Locomotion velocity, session 1	0.6	0.7	1.2	-0.1	1.1	-0.7	-1.0
Locomotion distance, session 1	0.3	0.4	0.9	0.9	0.7	-0.1	-0.5
Locomotion velocity, session 2	0.9	1.0	1.8	1.4	-0.9	1.2	0.1
Locomotion distance, session 2	0.9	1.3	3.4	1.8	-0.7	1.1	0.3
Locomotion velocity, session 3	0.1	0.1	0.1	0.4	-0.3	0.3	-0.3
Locomotion distance, session 3	0.3	0.4	1.2	0.3	1.1	-0.5	-0.1
Stereotopy head waving bouts, day 3	0.2	0.2	0.5	-0.1	-0.7	0.4	-0.4
Stereotopy head waving duration, day 3	0.2	0.2	0.3	-0.5	-0.5	-0.0	-0.5
Locomotion velocity, session 7	1.3	1.4	2.1	-1.0	1.4	-1.3	-1.0
Locomotion distance, session 7	0.2	0.2	0.5	-0.2	0.4	-0.4	-0.7
Stereotopy head waving bouts, day 7	0.2	0.2	0.3	0.6	-0.3	0.4	-0.4
Stereotopy head waving duration, day 7	0.3	0.3	0.4	0.6	-0.6	0.7	-0.2
Locomotion velocity, session 8	0.3	0.3	0.8	0.0	0.6	-0.3	-0.9
Locomotion distance, session 8	0.2	0.3	1.0	1.0	0.1	0.4	-0.1
Degree of sensitization distance	0.2	0.2	0.3	-0.3	-0.5	0.0	-0.4
Degree of sensitization stereotypy	0.8	0.9	1.7	1.3	-0.8	1.1	0.2
Conditioned locomotion	0.3	0.4	1.2	0.2	-0.2	0.3	1.1
Cocaine response after cond. corrected	0.2	0.2	0.6	-0.5	-0.8	0.2	-0.2
Cocaine response after cond. not corrected	0.6	0.6	1.3	0.7	-1.2	0.8	-0.1
Cocaine response before conditioning	2.4	2.9	7.8	2.8	-1.1	1.6	0.3
Saline control response	0.7	1.0	2.3	1.5	-0.8	1.0	0.0
Bone: connectivity density	0.1	0.2	0.4	-0.2	0.5	-0.3	-0.6
Bone: cortical apparent density	0.1	0.1	0.3	-0.6	0.0	-0.2	0.1
Bone: cortical area	0.4	0.7	1.6	1.3	-0.5	0.8	-0.4
Bone: cortical porosity	0.2	0.2	0.6	-0.5	0.0	-0.2	0.7
Bone: cortical porosity	0.4	0.4	1.3	0.1	-0.4	0.4	1.1
Bone: cortical thickness	0.1	0.2	0.4	-0.5	0.1	-0.1	-0.7
Bone: cortical thickness	0.1	0.1	0.3	0.6	-0.1	0.3	-0.1
Bone: cortical tissue density	0.1	0.1	0.4	-0.6	0.1	-0.2	0.1
Condit. Reinf. active minus inactive responses	0.6	0.7	1.6	0.5	-1.3	0.9	0.2
Condit. Reinf. active-inactive response ratio	0.7	0.8	1.7	0.3	-1.3	1.0	0.5
Condit. Reinf. active responses	0.4	0.5	1.0	0.6	-1.0	0.7	0.0
Condit. Reinf. inactive responses	0.2	0.2	0.4	0.3	0.5	-0.3	-0.6
Incentive salience index mean	0.5	0.6	1.2	0.8	-1.1	0.9	0.1
Condit. Reinf. lever presses	0.2	0.3	0.6	0.7	-0.6	0.6	0.2
Condit. Reinf. active minus inactive responses	0.3	0.4	1.1	1.0	0.5	-0.0	-0.5
Condit. Reinf. active-inactive response ratio	0.3	0.3	1.0	1.0	0.3	0.1	-0.5
Condit. Reinf. active responses	0.3	0.4	1.1	1.1	0.7	-0.1	-0.2
Condit. Reinf. inactive responses	0.2	0.2	0.6	-0.0	0.8	-0.4	0.2
Condit. Reinf. lever presses	0.6	0.8	1.3	1.1	-0.7	0.9	0.6
Condit. Reinf. lever reinforcers received	0.4	0.6	1.8	1.3	0.7	0.0	-0.1
Conditioned reinforcement - actives	0.9	0.9	2.3	0.1	-1.5	1.0	0.5
Conditioned reinforcement - inactives	1.3	1.5	2.2	1.2	-1.4	1.5	-0.4
Conditioned locomotion	0.8	1.0	2.0	0.7	-1.4	1.1	0.1
Patch foraging indifference point 0 sec	0.1	0.2	0.4	-0.1	-0.4	0.3	-0.6
Patch foraging indifference point AUC	2.6	3.0	4.0	2.0	-1.9	2.0	0.6
Delay disc. indifference point, 0s delay	0.1	0.2	0.3	-0.0	0.3	-0.4	-0.6
Delay disc. indifference point, 16s delay	0.5	0.5	1.4	-1.2	0.2	-0.2	0.6
Delay disc. indifference point, 2s delay	0.2	0.2	0.4	-0.5	0.5	-0.6	0.1
Delay disc. indifference point, 24s delay	0.5	0.5	0.9	-0.3	-0.9	0.6	0.9
Delay disc. indifference point, 4s delay	0.2	0.2	0.3	0.4	-0.5	0.5	-0.1
Delay disc. indifference point, 8s delay	1.0	1.0	2.3	-1.5	0.9	-0.8	0.6
Indifference point function ln k	2.0	2.7	4.0	-1.1	2.0	-1.7	-1.6
Indifference point function log k	2.0	2.7	4.0	-1.1	2.0	-1.7	-1.6
Patch foraging total patch changes 0 sec	0.1	0.2	0.4	-0.1	-0.5	0.4	-0.6
Patch foraging total patch changes 12 sec	1.2	1.5	2.4	1.3	-1.4	1.6	0.3
Patch foraging total patch changes 18 sec	1.1	1.4	2.1	1.5	-1.3	1.3	0.2
Patch foraging total patch changes 24 sec	1.6	2.0	3.1	1.8	-1.3	1.6	0.8
Patch foraging total patch changes 6 sec	0.9	1.4	2.2	1.1	-1.5	1.5	0.1
Patch foraging time to switch 0 sec	2.2	3.3	8.1	-2.9	1.3	-1.8	0.3
Patch foraging water rate 0 sec	1.7	2.7	4.8	2.2	-1.6	1.8	-0.5
Patch foraging water rate 12 sec	0.2	0.3	0.7	0.7	0.2	0.0	-0.9
Patch foraging water rate 18 sec	0.2	0.3	1.1	0.4	0.1	-0.0	-1.0
Patch foraging water rate 24 sec	0.3	0.4	1.2	0.2	0.5	-0.3	-1.1
Patch foraging water rate 6 sec	2.3	3.3	8.3	2.9	-1.2	1.6	0.8
Seeking ratio, delayed vs. immediate footshock	1.8	2.1	2.8	-1.3	1.7	-1.5	-1.3
Distance traveled before self-admin	0.1	0.2	0.4	0.4	0.1	0.1	-0.6
Distance traveled after self-admin	0.5	0.6	1.3	0.3	1.2	-0.7	-0.7
Extensor digitorum longus weight	1.2	4.5	6.5	2.4	-2.6	2.4	-0.6
Bone: elastic displacement	2.6	2.9	4.5	-2.1	1.4	-1.7	-1.5
Bone: elastic work	0.4	0.5	1.3	-0.3	0.5	-0.5	-1.2
Bone: endosteal estimation	0.3	0.7	2.5	1.6	0.3	0.3	0.0
Bone: endosteal perimeter	0.2	0.5	1.8	1.3	0.1	0.3	-0.2
Epididymis fat weight	0.7	1.6	2.7	-1.6	1.1	-1.4	-0.7
Delta time in closed arm before/after self-admin	0.1	0.1	0.3	0.5	0.1	0.3	0.4
Delta time in open arm before/after self-admin	0.3	0.3	0.5	0.7	-0.6	0.3	-0.3
Diff in mean of infusions in LGA sessions	1.8	2.0	3.0	-1.5	1.7	-1.7	0.3
Delay discount exponential model param	0.3	0.3	0.9	1.0	-0.2	0.2	-0.5
Extinction: sum of active levers before priming	0.6	0.6	1.0	-0.7	1.0	-0.9	-0.6
Active lever presses in extinction session 6	2.0	1.9	4.2	0.5	-1.2	1.3	2.0
Bone: final force	0.7	1.1	3.1	1.8	-0.5	0.9	0.2
Bone: final moment	0.8	1.3	3.9	2.0	-0.5	1.0	-0.1
Food consumed during 24 hour testing period	2.3	2.8	5.4	-1.5	2.3	-1.9	-0.3
Glucose	1.5	2.2	3.4	-1.8	1.4	-1.7	-0.9
Heart weight	0.6	0.9	1.6	1.0	-1.2	1.0	-0.1
Delay discount hyperbolic model param	0.1	0.2	0.5	0.7	-0.1	0.1	-0.4
Intermittent access intake day 1-15 change	0.1	0.1	0.2	0.4	0.0	-0.1	-0.3
Intermittent access intake escalation	0.0	0.0	0.1	0.1	0.1	-0.2	-0.2
Intermittent access intake escalation 2	0.1	0.1	0.1	0.2	0.3	-0.1	-0.3
Intermitt. access day 1 inactive lever presses	0.8	0.8	1.6	0.3	-1.3	1.2	0.6
Intermitt. access day 15 inactive lever presses	2.4	2.6	3.6	1.5	-1.7	1.9	1.3
Intermitt. access escalation Index	0.7	0.7	2.3	-0.6	-0.1	-0.0	1.5
Intermittent access day 1 total infusions	0.8	0.9	1.6	1.1	-1.3	1.0	-0.1
Intermittent access day 15 total infusions	0.1	0.1	0.4	0.0	-0.6	0.2	-0.2
Intermittent access terminal intake (last 3 days)	0.1	0.1	0.3	-0.1	-0.5	0.1	-0.5
Intermittent access total infusions	0.5	0.5	1.4	0.4	-1.2	0.7	-0.2
Intermittent access day 1 locomotion	0.3	0.3	0.9	-0.3	-0.1	-0.3	-0.9
Intermittent access day 15 total locomotion	0.2	0.2	0.4	-0.3	0.1	-0.5	-0.6
Intermittent access total locomotion	0.3	0.3	0.8	0.2	-0.6	0.1	-0.9
Intermittent access standard deviation	1.0	1.1	2.5	0.7	-0.8	0.9	1.6
Left kidney weight	5.9	16.7	26.8	5.2	-4.2	4.5	1.3
Right kidney weight	4.1	11.5	17.7	4.2	-3.6	3.8	1.0
Cocaine induced anxiety	1.6	1.8	3.1	-1.0	1.3	-1.2	-1.8
Post-drug Anxiety	0.1	0.1	0.3	0.1	0.2	-0.2	-0.5
Baseline Anxiety	0.3	0.3	0.7	0.2	-0.5	0.3	0.8
Tail length	0.3	1.0	1.6	1.3	-0.7	1.1	0.8
Length with tail	0.4	1.4	3.6	1.9	-0.7	1.2	0.1
Length without tail	0.2	0.5	1.6	1.3	-0.3	0.5	-0.2
Times rat made contact with spout	0.5	0.6	0.7	-0.7	0.8	-0.8	-0.7
Lifetime Intake	0.4	0.5	1.4	0.3	-1.2	0.7	-0.1
Liver weight, left	10.2	16.2	19.4	4.2	-4.4	4.4	3.0
Liver weight, right	2.9	4.8	7.2	1.9	-2.7	2.4	1.6
Locomotor activity	1.4	2.2	3.1	1.5	-1.6	1.8	0.8
Locomotor testing distance	0.7	1.1	1.5	1.2	-1.2	1.2	0.1
Locomotor testing rearing	4.6	7.2	11.0	3.3	-2.9	2.9	0.7
Locomotion in novel chamber	2.0	2.5	3.0	-1.6	1.6	-1.7	-1.3
Locomotion in novel chamber post-restriction	0.7	0.8	1.3	-1.0	0.9	-1.1	-0.4
Fecal boli incidents, locomotor time 1	0.4	0.5	1.2	-0.5	0.4	-0.5	-1.1
Change in fecal boli incidents, locomotor task	0.5	0.5	0.5	-0.7	0.7	-0.7	0.7
Time >=10cm from walls, locomotor time 1	0.1	0.1	0.2	-0.5	-0.1	-0.4	0.1
Bouts of movement, locomotor time 1	1.7	1.9	4.2	-0.8	2.0	-1.2	1.1
Total resting periods, locomotor time 1	2.4	2.6	5.7	-1.4	2.4	-1.6	0.7
Rest time, locomotor task time 1	0.5	0.6	1.7	-0.1	1.3	-0.7	-0.2
Distance moved, locomotor task time 1	0.7	0.8	2.0	0.2	-1.4	1.1	-0.1
Vertical activity count, locomotor time 1	0.3	0.3	0.8	-0.2	-0.9	0.4	-0.3
Time >=10cm from walls, locomotor time 2	0.0	0.0	0.1	-0.1	0.3	-0.1	0.1
Bouts of movement, locomotor time 2	1.6	1.7	2.6	-0.9	1.6	-1.2	1.4
Total resting periods, locomotor time 2	1.7	1.8	3.2	-1.1	1.8	-1.4	0.9
Rest time, locomotor task time 2	1.3	1.5	2.3	-0.9	1.3	-1.5	-1.1
Distance moved, locomotor task time 2	1.2	1.3	2.6	1.1	-1.1	1.6	0.6
Vertical activity count, locomotor time 2	0.6	0.7	0.9	0.7	-0.7	1.0	0.9
Light reinforcement 1	0.5	1.0	1.4	1.2	-0.8	1.1	0.9
Light reinforcement 2	1.1	1.5	2.2	0.6	-1.5	1.2	1.3
Bone: marrow area	0.3	0.7	2.8	1.7	0.2	0.3	0.1
Bone: maximum diameter	2.1	3.8	6.6	2.6	-1.8	2.1	1.1
Bone: maximum force	0.4	0.7	2.4	1.5	-0.3	0.7	-0.1
Bone: maximum moment	0.5	0.9	2.9	1.7	-0.3	0.7	-0.4
Mean time between licks in bursts	0.0	0.1	0.1	-0.3	-0.3	0.1	0.1
Mean num. licks in bursts	3.1	3.7	5.9	-1.8	2.4	-2.2	-1.0
Cd content in liver	0.2	0.2	0.5	0.1	0.7	-0.5	-0.2
Co content in liver	1.1	1.3	2.4	-1.0	1.5	-1.3	-0.5
Cu content in liver	0.4	0.5	1.1	1.0	-0.5	0.7	0.5
Fe content in liver	0.2	0.2	0.5	0.7	-0.3	0.5	0.1
K content in liver	1.3	1.3	2.0	1.4	-1.1	1.2	0.8
Mg content in liver	1.6	1.6	2.0	1.0	-1.4	1.3	1.3
Mn content in liver	0.8	1.0	1.9	0.7	-1.4	1.0	0.6
Na content in liver	0.1	0.1	0.2	-0.4	-0.0	-0.1	0.3
Rb content in liver	0.4	0.6	1.4	0.8	-0.3	0.5	1.2
Se content in liver	4.5	5.6	8.1	1.7	-2.8	2.6	2.2
Sr content in liver	0.3	0.3	0.7	-0.8	-0.5	0.1	-0.0
Zn content in liver	1.0	1.1	2.1	0.5	-1.4	1.1	0.9
Bone: minimum diameter	0.6	1.1	3.9	2.0	-0.0	0.7	-0.4
Time in familiar zone, hab. session 1	0.4	0.3	0.5	0.7	0.6	-0.3	-0.7
Time in novel zone, hab. session 1	1.1	1.1	2.1	0.4	-1.4	1.2	0.8
Total zone transitions, hab. session 1	0.2	0.3	1.0	1.0	0.3	0.1	-0.2
Total locomotion distance, hab. session 1	0.5	0.6	1.3	-0.1	1.1	-0.9	-0.7
Locomotion velocity, hab. session 1	1.0	1.4	2.5	-0.7	1.6	-1.3	-0.8
Time in familiar zone, hab. session 2	0.3	0.3	1.0	0.2	0.3	-0.3	-1.0
Time in novel zone, hab. session 2	0.7	0.7	2.2	0.1	-0.4	0.5	1.5
Total zone transitions, hab. session 2	0.7	0.9	3.1	1.8	-0.3	0.7	-0.1
Total locomotion distance, hab. session 2	0.5	0.6	1.3	-0.2	1.2	-0.9	-0.6
Locomotion velocity, hab. session 2	0.3	0.4	1.0	-0.0	1.0	-0.7	-0.5
Novel to familiar place preference ratio	0.5	0.5	0.7	0.8	-0.8	0.9	-0.1
Novelty place preference	0.4	0.4	0.7	0.9	-0.6	0.7	-0.1
Time in novel zone, NPP test	0.4	0.5	0.8	0.9	-0.7	0.8	-0.1
Total zone transitions, NPP test	0.2	0.3	0.9	0.9	-0.3	0.5	-0.0
Total locomotion distance, NPP test	0.1	0.1	0.2	0.5	0.1	0.1	-0.2
Locomotion velocity, NPP test	0.1	0.1	0.4	0.6	0.1	0.1	-0.2
Intraocular pressure	0.2	0.3	0.5	-0.0	0.7	-0.4	-0.6
Delta distance traveled before/after self-admin	0.3	0.4	0.8	-0.3	0.9	-0.7	0.2
Delta ambulatory time before/after self-admin	0.4	0.4	0.7	-0.6	0.8	-0.8	-0.1
Parametrial fat weight	0.6	1.1	3.9	-2.0	-0.3	-0.3	-0.6
Pavlov. Cond. lever latency	0.6	0.8	1.1	-0.9	1.1	-1.0	-0.5
Pavlov. Cond. magazine entry latency	1.2	1.6	2.2	0.8	-1.5	1.3	1.4
Pavlov. Cond. change in total contacts	0.1	0.1	0.2	-0.3	-0.1	0.0	0.4
Pavlov. Cond. index score	1.3	1.6	2.1	1.0	-1.5	1.3	1.2
Pavlov. Cond. latency score	0.7	0.8	1.2	0.6	-1.1	1.0	1.0
Pavlov. Cond. lever contacts	0.9	1.0	1.6	1.0	-1.3	1.1	0.6
Pavlov. Cond. magazine entry number	0.8	1.0	1.4	-0.8	1.2	-1.0	-1.0
Pavlov. Cond. intertrial magazine entries	0.7	0.9	2.4	-0.4	0.7	-0.7	-1.5
Pavlov. Cond. lever-magazine prob. diff.	1.5	1.8	2.7	1.1	-1.6	1.5	1.2
Pavlov. Cond. response bias	2.7	3.3	4.5	1.7	-2.1	2.0	1.4
Pavlov. Cond. lever latency	0.1	0.1	0.3	-0.1	0.5	-0.4	-0.2
Pavlov. Cond. magazine entry latency	0.1	0.1	0.3	-0.4	-0.4	0.0	0.5
Pavlov. Cond. change in total contacts	0.2	0.2	0.5	-0.1	0.7	-0.5	-0.2
Pavlov. Cond. index score	0.1	0.1	0.3	0.1	-0.3	0.2	0.6
Pavlov. Cond. latency score	0.1	0.1	0.1	-0.3	-0.1	-0.1	0.3
Pavlov. Cond. lever contacts	0.3	0.4	0.5	0.7	-0.7	0.7	0.2
Pavlov. Cond. magazine entry number	0.2	0.3	0.5	0.7	-0.4	0.5	-0.4
Pavlov. Cond. intertrial magazine entries	0.6	0.7	1.4	1.2	0.3	0.2	-1.2
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.2	0.3	0.3	-0.4	0.3	0.6
Pavlov. Cond. response bias	0.2	0.2	0.5	0.7	-0.4	0.5	0.2
Time in closed arm before self-admin	0.2	0.2	0.3	0.4	-0.5	0.5	-0.3
Time in closed arm after self-admin	0.1	0.1	0.2	-0.1	0.1	0.3	0.4
Time in open arm before self-admin	0.1	0.1	0.2	-0.0	0.5	-0.1	0.2
Time in open arm after self-admin	0.1	0.1	0.3	0.6	-0.1	0.0	-0.0
Bone: periosteal estimation	0.5	1.0	3.5	1.9	-0.2	0.7	-0.1
Bone: periosteal perimeter	0.5	0.8	2.9	1.7	-0.0	0.5	-0.3
Bone: post-yield work	0.2	0.3	0.5	0.7	0.5	0.0	0.5
Progressive ratio test 1 active lever presses	0.3	0.3	0.7	0.8	-0.3	0.3	-0.6
Progressive ratio test 1 breakpoint	0.2	0.2	0.4	0.6	-0.3	0.3	-0.5
Progressive ratio test 1 inactive lever presses	1.9	2.1	3.6	1.9	-1.5	1.6	0.4
Progressive ratio test 2 active lever presses	0.3	0.4	1.1	0.3	-1.0	0.6	-0.1
Progressive ratio test 2 breakpoint	0.3	0.4	1.0	0.3	-1.0	0.6	-0.1
Progressive ratio test 2 inactive lever presses	0.7	0.8	1.5	1.2	-1.0	0.9	-0.1
Incentive Sensitization - Responses	0.3	0.3	0.7	0.2	-0.8	0.5	-0.2
Incentive Sensitization - Breakpoint	0.3	0.3	0.8	0.2	-0.9	0.5	-0.1
Sum of active levers in priming session hrs 5-6	1.4	1.4	2.2	-1.5	1.3	-1.2	0.2
Progressive ratio	0.4	0.5	0.7	-0.5	0.7	-0.7	0.9
Food seeking constrained by brief footshock	3.0	3.7	4.8	-1.6	2.2	-2.2	-1.7
Seeking ratio, punishment vs. effort	1.0	1.2	2.6	-0.6	0.9	-0.9	-1.6
Retroperitoneal fat weight	0.6	2.0	7.0	-2.6	0.3	-1.0	-0.0
Reaction time number correct	1.4	2.0	2.9	1.6	-1.7	1.6	0.2
Reaction time mean minus median	0.5	0.7	1.4	-0.5	1.2	-1.0	-0.3
Reaction time mean minus median AUC	0.1	0.2	0.3	0.1	0.6	-0.5	-0.3
Reaction time num false alarms	4.2	5.6	7.4	2.5	-2.7	2.7	1.3
Reaction time num false alarms AUC	3.2	4.4	5.8	2.3	-2.4	2.4	0.9
Reaction time trials correct on left	1.4	2.0	2.9	1.6	-1.7	1.6	0.2
Reaction time trials on left	1.5	2.1	3.0	1.6	-1.7	1.7	0.2
Reaction time mean	1.0	1.3	1.8	-1.3	1.2	-1.3	-0.5
Reaction time mean AUC	0.9	1.3	2.2	-1.5	1.0	-1.2	-0.6
Median of all reaction times	0.8	1.0	1.8	-1.4	1.0	-1.2	-0.3
Reaction time omissions	0.3	0.4	0.7	0.5	-0.8	0.8	0.4
Reaction time false alarm rate	0.6	0.8	1.0	0.9	-0.9	1.0	0.7
Reaction time premature initiation rate	1.8	2.4	2.8	-1.7	1.2	-1.6	-1.7
Reaction time premature initiations	0.7	1.0	2.4	-0.9	0.3	-0.8	-1.6
Std. dev. reaction times	0.6	0.8	1.1	-0.7	1.0	-1.0	-0.7
Reaction time trials completed	1.5	2.1	3.0	1.6	-1.7	1.7	0.2
Reaction time trials AUC	1.9	2.7	4.1	1.7	-2.0	1.9	0.2
Run reversals in cocaine runway, females	0.7	0.7	1.5	-1.2	0.5	-0.9	-0.2
Run reversals in cocaine runway, males	0.7	0.7	1.3	1.1	-0.7	0.9	0.5
Latency to leave start box in cocaine runway	0.5	0.6	1.1	-0.5	1.0	-0.9	-0.5
Latency to leave start box in cocaine runway, F	0.3	0.3	0.7	-0.2	0.5	-0.6	-0.9
Latency to leave start box in cocaine runway, M	0.2	0.2	0.5	0.4	0.1	0.2	0.7
Std. dev. time between licks in bursts	0.7	0.8	1.0	1.0	-0.8	1.0	0.8
Total sessions with >9 infusions	1.7	1.8	3.7	1.1	-1.9	1.5	0.3
Short access day 1 total inactive lever presses	1.2	1.4	2.3	1.5	-1.4	1.1	0.4
Short access day 10 total inactive lever presses	0.3	0.4	0.8	-0.9	0.7	-0.5	-0.1
Short access day 1 total infusions	0.2	0.2	0.6	0.5	-0.7	0.4	-0.1
Short access day 10 total infusions	2.0	2.2	2.9	1.6	-1.7	1.6	0.9
Short access total infusions	0.3	0.3	0.9	0.4	-1.0	0.5	0.1
Short access day 1 locomotion	0.4	0.4	0.9	0.3	-1.0	0.7	-0.5
Short access day 10 total locomotion	0.7	0.8	1.0	-0.9	0.7	-1.0	-0.8
Short access total locomotion	0.1	0.1	0.4	-0.3	-0.0	-0.2	-0.6
One hour access (0.3 mA shock)	0.0	0.1	0.1	-0.2	0.2	-0.3	-0.1
Compulsive drug intake	0.0	0.0	0.1	-0.2	0.2	-0.3	-0.1
One hour access (shock baseline)	0.6	0.7	1.0	0.8	-1.0	0.9	0.5
Social response proportion	1.1	1.2	1.8	1.0	-1.2	1.3	0.7
Social responses	2.4	3.1	5.5	2.3	-1.5	1.9	1.1
Social time	0.7	0.9	2.1	0.7	1.5	-0.5	0.9
Soleus weight	0.2	0.7	1.2	0.6	-1.1	1.0	0.5
Bone: stiffness	1.3	2.1	4.7	2.2	-1.1	1.5	0.6
Tibialis anterior weight	1.9	6.6	13.5	1.9	-3.7	3.1	0.0
Time to tail flick, vehicle, before self-admin	0.7	0.7	2.3	-0.4	-0.7	0.2	-1.5
Time to tail flick, vehicle, after self-admin	0.3	0.3	0.6	-0.6	0.8	-0.5	0.0
Time to tail flick, test, before self-admin	1.9	1.8	2.3	-0.9	1.5	-1.4	-1.5
Time to tail flick, test, after self-admin	0.1	0.1	0.1	0.4	0.1	0.3	-0.1
Delta time to tail flick, vehicle, before/after SA	0.3	0.3	0.8	-0.1	0.7	-0.2	0.9
Delta time to tail flick, test, before/after SA	0.7	0.6	1.2	0.5	-1.1	1.0	0.0
Tibia length	1.9	5.4	12.5	3.5	-1.1	2.1	1.9
Ambulatory time before self-admin	0.1	0.1	0.4	0.2	0.1	-0.1	-0.6
Ambulatory time after self-admin	0.9	1.0	1.9	-0.2	1.4	-1.1	-0.9
Bone: tissue strength	0.0	0.0	0.1	-0.2	0.2	-0.2	-0.1
Total heroin consumption	0.1	0.2	0.3	-0.5	-0.2	0.0	0.6
Bone: trabecular number	0.5	0.8	1.4	-0.6	1.2	-0.9	-0.7
Bone: trabecular spacing	0.3	0.4	0.8	0.4	-0.9	0.6	-0.1
Bone: trabecular thickness	0.1	0.1	0.2	0.4	-0.2	0.3	-0.5
Bone: trabecular tissue density	0.4	0.5	1.1	-0.4	-1.1	0.6	0.8
Water consumed over 24 hours	0.4	0.5	1.0	-0.2	1.0	-0.7	-0.6
Number of responses in last shaping day	0.5	0.5	0.9	0.1	-1.0	0.5	0.8