Hub : Genes

LOC120097392

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression LOC120097392 0.49 0.16 5.8e-07 0.18 0.16 0.19 0.21 5.4e-05 1.3e-04 2.5e-05 1.0e-05
2 BLA gene expression LOC120097392 0.49 0.12 0.0e+00 0.33 0.36 0.37 0.37 2.2e-18 5.9e-20 8.8e-21 6.5e-21
3 Adipose gene expression LOC120097392 0.62 0.01 0.0e+00 0.31 0.31 0.32 0.32 3.9e-35 1.7e-35 4.6e-36 6.8e-36
4 PL gene expression LOC120097392 0.61 0.11 0.0e+00 0.41 0.36 0.44 0.34 1.1e-47 9.9e-41 3.9e-53 2.8e-38
5 Brain gene expression LOC120097392 0.67 0.12 0.0e+00 0.54 0.43 0.57 0.51 7.0e-60 6.9e-43 1.6e-63 1.6e-54
6 pVTA gene expression LOC120097392 0.6 0.16 0.0e+00 0.29 0.24 0.32 0.34 5.1e-13 5.8e-11 1.2e-14 1.5e-15
7 NAcc gene expression LOC120097392 0.35 0.11 0.0e+00 0.31 0.32 0.35 0.34 2.4e-36 1.6e-38 4.8e-42 2.0e-40
8 OFC gene expression LOC120097392 0.21 0.13 4.6e-03 0.1 0.05 0.06 0.07 3.0e-03 2.4e-02 1.4e-02 1.2e-02
9 Brain mRNA stability LOC120097392 0.1 0.06 9.4e-07 0.08 0.06 0.06 0.07 5.2e-08 1.9e-06 1.2e-06 2.8e-07
10 IL gene expression LOC120097392 0.59 0.15 1.7e-10 0.36 0.31 0.34 0.32 1.1e-09 2.8e-08 3.9e-09 1.7e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density1.32.13.1-1.8-1.71.81.61.4-1.31.41.11.01.1
Area under the delay curve0.10.10.20.20.2-0.3-0.2-0.30.4-0.2-0.3-0.2-0.3
BMI with tail2.47.99.8-2.6-2.62.52.62.9-3.02.83.02.93.1
BMI without tail2.65.56.1-2.3-2.22.52.32.3-2.32.32.52.42.3
Body weight2.410.111.8-2.9-2.92.93.13.2-3.33.33.43.33.4
Weight adjusted by age0.70.81.10.80.8-0.8-1.0-1.00.9-1.1-0.8-0.9-1.0
Bone surface1.01.82.6-1.6-1.61.61.41.2-1.31.31.11.01.1
Bone volume1.42.32.7-1.6-1.61.61.51.4-1.51.61.51.41.4
Breakpoint value in progressive ratio session0.30.31.00.50.6-1.0-0.4-0.60.5-0.5-0.6-0.7-0.1
Number of licking bursts0.10.10.1-0.4-0.40.30.30.3-0.30.30.20.30.2
Context. condit. distance diff. score0.10.10.20.10.00.10.20.3-0.20.20.30.50.4
Locomotion velocity, session 16.26.77.52.62.7-2.7-2.7-2.72.5-2.5-2.5-2.5-2.4
Locomotion distance, session 16.58.39.93.13.1-3.2-3.1-3.02.7-2.8-2.7-2.6-2.5
Locomotion velocity, session 24.45.26.42.52.5-2.4-2.4-2.32.2-2.3-2.0-2.1-1.9
Locomotion distance, session 23.24.55.72.42.3-2.3-2.3-2.21.9-2.1-1.9-1.8-1.8
Locomotion velocity, session 34.24.96.22.32.4-2.5-2.4-2.42.1-2.0-2.0-2.0-1.9
Locomotion distance, session 30.80.92.01.31.3-1.4-1.2-1.10.7-0.8-0.4-0.4-0.4
Stereotopy head waving bouts, day 30.50.61.0-1.0-1.00.80.80.8-0.80.80.70.70.7
Stereotopy head waving duration, day 31.21.42.2-1.5-1.51.41.21.2-1.11.10.80.90.8
Locomotion velocity, session 75.66.17.92.82.7-2.8-2.6-2.62.4-2.3-2.1-2.1-2.2
Locomotion distance, session 72.43.15.32.32.1-2.1-1.9-1.81.6-1.7-1.4-1.2-1.3
Stereotopy head waving bouts, day 72.22.43.2-1.8-1.71.81.61.7-1.41.61.41.31.3
Stereotopy head waving duration, day 71.41.72.5-1.6-1.41.61.41.4-1.11.21.11.01.0
Locomotion velocity, session 89.211.012.03.43.5-3.3-3.4-3.33.2-3.3-3.3-3.3-3.2
Locomotion distance, session 82.33.34.72.22.1-2.0-2.0-1.91.7-1.8-1.6-1.4-1.4
Degree of sensitization distance0.10.10.30.50.3-0.2-0.2-0.20.3-0.4-0.3-0.2-0.3
Degree of sensitization stereotypy0.80.91.5-1.2-1.11.21.11.1-0.80.90.80.60.6
Conditioned locomotion3.94.65.3-1.9-2.02.02.12.2-2.12.12.22.32.3
Cocaine response after cond. corrected0.00.00.1-0.2-0.20.20.10.3-0.10.1-0.0-0.00.1
Cocaine response after cond. not corrected0.10.10.10.20.2-0.0-0.2-0.10.2-0.3-0.4-0.3-0.3
Cocaine response before conditioning0.80.91.41.21.1-0.9-1.0-1.01.1-0.9-0.8-0.7-1.0
Saline control response1.01.32.1-0.7-0.90.80.91.1-1.31.21.41.51.4
Bone: connectivity density0.71.12.3-1.5-1.41.51.21.0-0.80.90.40.30.4
Bone: cortical apparent density0.20.20.30.60.5-0.2-0.5-0.40.4-0.5-0.5-0.5-0.5
Bone: cortical area10.015.117.1-3.8-3.83.63.73.7-3.94.14.14.04.0
Bone: cortical porosity0.70.81.60.91.0-1.3-1.0-1.10.9-0.7-0.6-0.6-0.6
Bone: cortical porosity0.70.71.60.90.9-1.3-1.0-1.00.8-0.7-0.6-0.5-0.5
Bone: cortical thickness4.87.88.4-2.8-2.92.82.72.7-2.72.92.92.82.8
Bone: cortical thickness5.86.78.0-2.8-2.72.72.62.5-2.42.62.52.62.5
Bone: cortical tissue density0.50.60.80.90.8-0.6-0.9-0.70.8-0.8-0.8-0.8-0.8
Condit. Reinf. active minus inactive responses0.10.10.3-0.1-0.00.00.10.1-0.10.30.50.50.3
Condit. Reinf. active-inactive response ratio2.62.83.1-1.7-1.71.71.71.6-1.51.71.81.81.6
Condit. Reinf. active responses0.40.50.90.80.8-0.9-0.8-0.90.8-0.6-0.4-0.4-0.6
Condit. Reinf. inactive responses4.25.06.32.32.2-2.5-2.3-2.42.2-2.1-2.0-2.1-2.1
Incentive salience index mean0.10.20.3-0.4-0.30.30.40.2-0.20.40.50.60.4
Condit. Reinf. lever presses0.10.10.3-0.5-0.40.40.30.1-0.10.30.30.40.2
Condit. Reinf. active minus inactive responses0.20.20.3-0.5-0.50.50.50.6-0.50.50.40.50.4
Condit. Reinf. active-inactive response ratio1.51.61.9-1.2-1.31.21.21.4-1.31.21.21.21.2
Condit. Reinf. active responses0.10.10.2-0.2-0.30.30.30.4-0.40.40.40.30.4
Condit. Reinf. inactive responses1.62.02.31.51.4-1.5-1.4-1.51.3-1.3-1.3-1.4-1.3
Condit. Reinf. lever presses0.10.10.40.10.1-0.10.10.1-0.20.40.60.50.5
Condit. Reinf. lever reinforcers received0.30.40.5-0.5-0.50.50.60.7-0.70.60.70.60.6
Conditioned reinforcement - actives0.40.41.1-0.4-0.50.50.50.5-0.50.70.81.00.8
Conditioned reinforcement - inactives2.32.64.8-1.1-1.31.31.31.5-1.41.62.22.21.8
Conditioned locomotion0.10.20.60.40.3-0.2-0.3-0.20.40.10.60.70.1
Patch foraging indifference point 0 sec0.71.12.21.51.2-1.3-1.2-1.21.0-0.9-0.6-0.6-0.6
Patch foraging indifference point AUC0.30.30.5-0.6-0.60.70.70.5-0.30.50.50.40.4
Delay disc. indifference point, 0s delay1.51.62.1-1.1-1.11.11.21.2-1.31.31.41.41.4
Delay disc. indifference point, 16s delay0.60.60.90.80.9-0.9-0.8-0.70.7-0.8-0.8-0.8-0.7
Delay disc. indifference point, 2s delay0.20.20.60.40.3-0.3-0.4-0.60.8-0.3-0.3-0.2-0.5
Delay disc. indifference point, 24s delay2.22.12.61.31.3-1.3-1.3-1.51.5-1.5-1.6-1.6-1.6
Delay disc. indifference point, 4s delay0.10.10.2-0.3-0.40.40.40.10.00.40.30.40.2
Delay disc. indifference point, 8s delay0.00.00.10.00.1-0.2-0.1-0.10.2-0.1-0.1-0.1-0.0
Indifference point function ln k0.00.00.10.30.2-0.3-0.2-0.0-0.10.00.10.20.2
Indifference point function log k0.00.00.10.30.2-0.3-0.2-0.0-0.10.00.10.20.2
Patch foraging total patch changes 0 sec0.50.81.71.31.1-1.2-1.0-0.90.8-0.7-0.5-0.5-0.4
Patch foraging total patch changes 12 sec0.50.71.41.21.0-1.0-1.0-0.80.7-0.7-0.4-0.4-0.3
Patch foraging total patch changes 18 sec1.11.42.11.41.3-1.4-1.2-1.31.3-1.1-0.8-0.9-0.9
Patch foraging total patch changes 24 sec0.00.00.10.10.1-0.3-0.1-0.20.3-0.1-0.00.1-0.1
Patch foraging total patch changes 6 sec0.20.30.5-0.3-0.40.40.40.4-0.40.60.70.70.6
Patch foraging time to switch 0 sec0.81.32.30.80.9-0.9-1.0-1.00.9-1.3-1.4-1.5-1.3
Patch foraging water rate 0 sec2.33.65.0-1.7-1.81.71.91.8-1.72.12.12.21.9
Patch foraging water rate 12 sec0.71.11.5-0.9-0.90.80.91.0-1.21.01.11.21.2
Patch foraging water rate 18 sec0.70.91.2-1.0-0.91.10.91.0-1.00.91.00.90.8
Patch foraging water rate 24 sec4.86.77.7-2.4-2.42.62.52.7-2.72.62.72.82.5
Patch foraging water rate 6 sec0.71.11.6-1.0-1.01.11.01.0-0.91.11.11.30.9
Seeking ratio, delayed vs. immediate footshock1.51.83.5-0.9-1.00.61.21.4-1.41.41.51.61.9
Distance traveled before self-admin0.00.00.20.20.2-0.2-0.20.2-0.5-0.1-0.1-0.10.2
Distance traveled after self-admin0.40.41.0-0.1-0.30.20.40.6-1.00.60.80.80.7
Extensor digitorum longus weight0.10.41.01.00.9-1.0-0.6-0.40.2-0.20.40.30.2
Bone: elastic displacement0.91.01.20.90.9-0.9-1.0-1.01.0-1.0-1.1-1.1-1.1
Bone: elastic work0.70.81.0-1.0-1.01.00.90.8-0.90.90.90.90.9
Bone: endosteal estimation6.413.915.9-3.5-3.53.33.63.7-4.03.84.03.94.0
Bone: endosteal perimeter4.18.610.1-2.7-2.72.52.92.9-3.03.03.23.13.2
Epididymis fat weight0.41.02.2-1.2-1.31.51.11.1-0.80.90.60.60.4
Delta time in closed arm before/after self-admin1.11.11.4-1.1-1.11.21.01.1-1.11.01.01.00.9
Delta time in open arm before/after self-admin0.20.20.70.90.5-0.9-0.4-0.1-0.30.10.40.20.3
Diff in mean of infusions in LGA sessions3.43.84.51.71.8-1.8-1.7-2.12.0-2.1-2.1-2.1-2.0
Delay discount exponential model param0.20.20.4-0.2-0.30.40.30.5-0.60.40.40.40.4
Extinction: sum of active levers before priming2.62.63.61.71.7-1.9-1.5-1.81.9-1.5-1.3-1.6-1.2
Active lever presses in extinction session 60.50.50.80.50.6-0.9-0.6-0.60.6-0.7-0.8-0.9-0.2
Bone: final force10.016.217.7-4.0-4.03.84.03.9-4.04.14.24.24.2
Bone: final moment9.014.516.1-3.7-3.83.63.73.6-3.83.94.04.04.0
Food consumed during 24 hour testing period0.81.02.21.31.2-1.5-1.2-1.10.8-0.7-0.5-0.5-0.5
Glucose0.10.10.30.50.5-0.5-0.4-0.30.2-0.4-0.3-0.4-0.1
Heart weight0.00.00.00.20.1-0.1-0.10.00.00.0-0.1-0.1-0.2
Delay discount hyperbolic model param0.10.20.4-0.3-0.30.40.30.5-0.70.30.40.30.4
Intermittent access intake day 1-15 change0.00.00.1-0.2-0.30.10.10.1-0.1-0.0-0.3-0.10.0
Intermittent access intake escalation0.10.10.2-0.3-0.30.20.10.10.0-0.1-0.5-0.3-0.2
Intermittent access intake escalation 20.50.50.7-0.7-0.80.70.70.8-0.80.60.50.60.8
Intermitt. access day 1 inactive lever presses0.10.10.3-0.2-0.20.30.20.1-0.20.30.60.50.3
Intermitt. access day 15 inactive lever presses0.00.00.1-0.2-0.30.40.20.1-0.10.20.10.2-0.0
Intermitt. access escalation Index3.43.04.7-2.2-1.92.01.91.8-1.81.61.41.31.4
Intermittent access day 1 total infusions0.30.30.70.70.7-0.7-0.4-0.30.20.20.80.80.5
Intermittent access day 15 total infusions0.50.51.10.91.0-1.0-0.9-0.80.8-0.5-0.3-0.2-0.3
Intermittent access terminal intake (last 3 days)0.30.30.70.80.8-0.8-0.7-0.50.4-0.20.20.30.1
Intermittent access total infusions0.30.30.60.80.8-0.7-0.6-0.50.5-0.20.30.40.0
Intermittent access day 1 locomotion0.90.92.11.31.4-1.4-1.1-1.11.0-0.6-0.1-0.1-0.2
Intermittent access day 15 total locomotion0.20.20.40.60.6-0.5-0.4-0.1-0.0-0.10.50.50.3
Intermittent access total locomotion0.30.30.80.90.9-0.8-0.7-0.50.4-0.20.40.40.1
Intermittent access standard deviation1.71.72.3-1.2-1.41.41.31.3-1.11.41.31.51.3
Left kidney weight0.41.11.6-1.0-1.21.11.31.2-0.91.00.90.80.9
Right kidney weight0.41.21.7-0.8-0.90.91.01.2-1.21.21.31.31.3
Cocaine induced anxiety0.30.30.6-0.6-0.60.50.70.7-0.80.50.20.40.6
Post-drug Anxiety0.10.10.40.70.4-0.5-0.5-0.30.2-0.2-0.1-0.1-0.2
Baseline Anxiety0.30.30.60.80.8-0.6-0.6-0.50.5-0.40.1-0.1-0.3
Tail length0.10.20.3-0.4-0.40.50.40.3-0.40.40.50.50.3
Length with tail0.00.00.1-0.0-0.10.10.20.1-0.20.30.30.30.3
Length without tail0.20.40.9-0.3-0.40.10.50.5-0.70.70.70.71.0
Times rat made contact with spout0.91.12.21.51.3-1.5-1.3-1.10.8-0.7-0.4-0.3-0.4
Lifetime Intake0.40.51.11.01.0-1.0-0.8-0.70.7-0.30.30.3-0.0
Liver weight, left0.71.01.9-0.8-0.80.80.90.9-0.91.11.31.41.1
Liver weight, right0.30.40.9-0.4-0.50.50.40.6-0.80.70.81.00.8
Locomotor activity0.81.31.6-1.1-1.11.01.01.1-1.21.11.31.21.2
Locomotor testing distance3.04.95.4-2.3-2.32.22.22.3-2.32.22.22.12.1
Locomotor testing rearing2.03.13.9-1.8-1.81.61.61.8-2.01.71.71.81.8
Locomotion in novel chamber0.20.20.50.70.5-0.7-0.3-0.50.6-0.00.10.1-0.1
Locomotion in novel chamber post-restriction0.60.71.4-0.7-0.80.70.71.0-1.20.90.80.80.7
Fecal boli incidents, locomotor time 10.10.10.2-0.3-0.40.20.40.3-0.40.30.20.10.3
Change in fecal boli incidents, locomotor task0.10.10.20.40.40.1-0.40.2-0.4-0.10.10.20.0
Time >=10cm from walls, locomotor time 11.41.41.71.21.1-1.1-1.2-1.11.3-1.1-1.2-1.1-1.3
Bouts of movement, locomotor time 10.00.10.1-0.1-0.20.20.20.3-0.30.20.30.30.2
Total resting periods, locomotor time 10.00.00.00.1-0.00.0-0.00.1-0.0-0.1-0.1-0.2-0.1
Rest time, locomotor task time 10.70.81.1-0.9-0.90.91.01.0-1.00.90.70.60.9
Distance moved, locomotor task time 10.50.51.4-0.5-0.60.60.70.4-0.20.81.01.20.5
Vertical activity count, locomotor time 10.50.51.0-0.4-0.50.60.60.6-0.70.80.91.00.5
Time >=10cm from walls, locomotor time 22.72.83.3-1.6-1.71.81.71.7-1.71.81.61.71.5
Bouts of movement, locomotor time 20.70.70.90.90.9-0.8-0.9-0.80.9-0.8-0.7-0.8-0.8
Total resting periods, locomotor time 20.50.50.60.70.8-0.8-0.7-0.70.8-0.7-0.6-0.8-0.7
Rest time, locomotor task time 20.70.81.1-1.0-1.01.00.91.0-1.00.70.50.50.8
Distance moved, locomotor task time 21.51.72.6-1.1-1.31.21.41.1-1.01.41.61.61.2
Vertical activity count, locomotor time 24.04.35.2-1.8-1.92.02.12.1-2.12.22.32.22.0
Light reinforcement 10.10.20.30.30.4-0.5-0.5-0.50.5-0.4-0.5-0.4-0.3
Light reinforcement 20.91.31.80.91.1-1.2-1.1-1.11.0-1.2-1.3-1.3-1.0
Bone: marrow area6.113.215.2-3.4-3.43.23.53.6-3.93.73.93.83.9
Bone: maximum diameter3.86.98.7-2.5-2.42.32.52.4-2.72.82.92.82.9
Bone: maximum force14.024.225.0-5.0-4.94.84.94.8-4.95.05.04.95.0
Bone: maximum moment12.421.422.4-4.7-4.64.44.64.5-4.64.74.74.74.7
Mean time between licks in bursts2.12.93.61.51.6-1.6-1.6-1.71.7-1.7-1.8-1.9-1.8
Mean num. licks in bursts0.50.61.21.11.0-1.0-0.9-0.80.6-0.6-0.3-0.4-0.3
Cd content in liver0.00.00.00.00.0-0.0-0.10.1-0.2-0.0-0.00.20.0
Co content in liver0.50.61.00.90.9-1.0-0.9-0.90.6-0.7-0.6-0.6-0.5
Cu content in liver1.62.03.41.91.7-1.8-1.6-1.41.1-1.3-0.9-0.9-1.0
Fe content in liver0.20.30.40.40.5-0.5-0.5-0.60.6-0.4-0.5-0.4-0.6
K content in liver0.10.10.20.50.4-0.4-0.4-0.40.4-0.4-0.3-0.3-0.3
Mg content in liver0.00.00.10.20.2-0.3-0.2-0.10.1-0.10.00.00.1
Mn content in liver1.21.42.40.80.8-0.9-0.8-1.21.4-1.0-1.4-1.4-1.6
Na content in liver0.20.20.30.40.3-0.5-0.4-0.50.5-0.4-0.4-0.5-0.5
Rb content in liver0.91.11.7-0.9-0.90.80.90.9-1.21.11.21.31.3
Se content in liver0.10.10.3-0.2-0.10.30.0-0.10.3-0.1-0.4-0.3-0.5
Sr content in liver0.20.20.3-0.3-0.30.50.40.3-0.20.50.50.40.3
Zn content in liver2.12.44.52.11.9-2.0-1.8-1.61.3-1.3-0.8-1.0-0.9
Bone: minimum diameter8.215.418.2-3.7-3.73.53.83.7-4.04.14.34.14.2
Time in familiar zone, hab. session 14.34.04.5-1.9-2.01.92.12.0-1.92.12.02.01.9
Time in novel zone, hab. session 11.31.31.61.21.3-1.1-1.3-1.21.0-1.2-1.0-1.1-1.0
Total zone transitions, hab. session 12.43.45.42.12.1-2.3-2.0-2.01.6-1.7-1.4-1.3-1.3
Total locomotion distance, hab. session 11.72.43.41.61.6-1.8-1.6-1.61.5-1.4-1.4-1.4-1.4
Locomotion velocity, hab. session 12.13.04.21.81.8-2.0-1.8-1.81.6-1.6-1.7-1.6-1.5
Time in familiar zone, hab. session 20.30.30.91.00.8-0.8-0.6-0.60.6-0.4-0.1-0.0-0.1
Time in novel zone, hab. session 20.00.00.1-0.3-0.20.30.10.2-0.30.0-0.1-0.1-0.0
Total zone transitions, hab. session 21.92.43.11.71.8-1.7-1.7-1.61.4-1.5-1.4-1.4-1.3
Total locomotion distance, hab. session 21.31.72.21.41.5-1.5-1.4-1.31.2-1.2-1.2-1.2-1.0
Locomotion velocity, hab. session 21.11.51.81.31.4-1.3-1.3-1.31.1-1.2-1.2-1.2-1.0
Novel to familiar place preference ratio0.10.10.10.30.2-0.2-0.3-0.30.3-0.3-0.2-0.3-0.4
Novelty place preference0.40.40.50.70.6-0.6-0.7-0.70.6-0.6-0.5-0.5-0.7
Time in novel zone, NPP test0.40.40.50.70.6-0.6-0.7-0.70.6-0.6-0.5-0.6-0.7
Total zone transitions, NPP test2.12.93.91.92.0-1.9-1.9-1.81.6-1.7-1.4-1.4-1.4
Total locomotion distance, NPP test1.31.82.41.51.5-1.6-1.5-1.41.2-1.3-1.2-1.1-1.1
Locomotion velocity, NPP test1.31.92.41.51.5-1.5-1.5-1.51.3-1.3-1.3-1.1-1.2
Intraocular pressure0.81.01.51.21.1-1.1-1.2-1.01.0-1.1-0.8-0.8-0.8
Delta distance traveled before/after self-admin0.00.00.20.2-0.00.1-0.1-0.20.2-0.1-0.00.1-0.4
Delta ambulatory time before/after self-admin0.00.00.20.40.1-0.2-0.2-0.20.1-0.00.20.3-0.2
Parametrial fat weight1.73.34.3-1.9-1.91.91.92.0-2.11.61.51.61.7
Pavlov. Cond. lever latency0.10.20.4-0.4-0.50.40.50.6-0.60.30.30.10.3
Pavlov. Cond. magazine entry latency0.10.10.2-0.4-0.40.50.40.3-0.20.30.40.40.3
Pavlov. Cond. change in total contacts0.00.00.1-0.00.0-0.0-0.1-0.20.2-0.1-0.1-0.0-0.2
Pavlov. Cond. index score0.00.00.0-0.1-0.10.10.1-0.10.2-0.0-0.00.1-0.1
Pavlov. Cond. latency score0.10.20.3-0.4-0.40.50.40.3-0.20.40.40.50.3
Pavlov. Cond. lever contacts0.60.81.10.70.8-0.8-0.9-1.01.0-0.9-0.9-0.7-0.9
Pavlov. Cond. magazine entry number0.00.00.1-0.2-0.20.10.10.2-0.30.20.10.10.2
Pavlov. Cond. intertrial magazine entries1.72.12.51.41.4-1.6-1.5-1.51.4-1.3-1.4-1.4-1.4
Pavlov. Cond. lever-magazine prob. diff.0.20.30.50.40.4-0.3-0.4-0.60.7-0.5-0.5-0.5-0.6
Pavlov. Cond. response bias1.21.52.01.21.2-1.1-1.2-1.31.4-1.2-1.2-1.1-1.3
Pavlov. Cond. lever latency1.01.32.4-1.5-1.41.31.31.2-1.01.00.80.80.8
Pavlov. Cond. magazine entry latency1.92.22.51.61.6-1.4-1.5-1.51.5-1.4-1.4-1.5-1.4
Pavlov. Cond. change in total contacts0.40.51.21.11.0-1.1-0.9-0.70.5-0.5-0.3-0.3-0.3
Pavlov. Cond. index score1.41.92.51.61.6-1.5-1.5-1.41.3-1.2-1.1-1.2-1.2
Pavlov. Cond. latency score1.51.82.61.61.6-1.5-1.5-1.41.3-1.2-1.1-1.1-1.1
Pavlov. Cond. lever contacts0.50.61.31.11.0-1.0-0.9-0.80.6-0.6-0.5-0.5-0.5
Pavlov. Cond. magazine entry number0.91.11.5-1.2-1.21.11.11.1-1.01.00.91.00.9
Pavlov. Cond. intertrial magazine entries2.33.13.5-1.9-1.91.81.81.8-1.71.71.61.81.6
Pavlov. Cond. lever-magazine prob. diff.1.62.02.61.61.6-1.5-1.5-1.51.3-1.3-1.2-1.2-1.2
Pavlov. Cond. response bias1.01.32.01.41.4-1.3-1.3-1.21.0-1.0-0.9-0.9-0.9
Time in closed arm before self-admin0.20.20.6-0.7-0.60.80.50.20.10.2-0.10.0-0.3
Time in closed arm after self-admin2.02.04.3-1.9-1.82.11.61.4-1.01.20.80.90.5
Time in open arm before self-admin0.10.10.40.10.2-0.1-0.3-0.30.2-0.4-0.6-0.5-0.3
Time in open arm after self-admin0.40.41.31.00.8-1.1-0.6-0.4-0.0-0.20.20.00.4
Bone: periosteal estimation11.724.227.0-4.7-4.84.54.84.8-5.15.05.25.15.1
Bone: periosteal perimeter5.89.611.0-3.0-3.02.83.02.9-3.13.23.33.33.3
Bone: post-yield work4.76.46.9-2.6-2.62.62.62.5-2.52.52.52.52.4
Progressive ratio test 1 active lever presses0.30.41.10.30.3-0.40.10.1-0.10.61.01.00.9
Progressive ratio test 1 breakpoint0.30.40.90.50.6-0.6-0.1-0.0-0.10.41.00.90.8
Progressive ratio test 1 inactive lever presses0.20.20.60.20.2-0.4-0.1-0.0-0.00.40.60.80.7
Progressive ratio test 2 active lever presses1.01.02.41.51.4-1.3-1.2-1.00.9-0.8-0.00.0-0.4
Progressive ratio test 2 breakpoint0.70.81.91.41.3-1.1-1.1-0.90.8-0.60.10.2-0.1
Progressive ratio test 2 inactive lever presses0.40.41.1-0.4-0.40.40.50.5-0.40.70.91.00.8
Incentive Sensitization - Responses1.61.62.91.71.6-1.3-1.6-1.41.4-1.3-0.6-0.6-0.9
Incentive Sensitization - Breakpoint1.61.62.81.71.6-1.2-1.6-1.41.3-1.3-0.6-0.6-0.9
Sum of active levers in priming session hrs 5-60.10.10.1-0.4-0.2-0.10.30.00.10.1-0.2-0.30.3
Progressive ratio0.00.00.00.1-0.0-0.00.0-0.0-0.00.1-0.10.0-0.1
Food seeking constrained by brief footshock2.22.73.4-1.8-1.81.81.81.4-1.21.81.51.61.5
Seeking ratio, punishment vs. effort0.20.20.4-0.6-0.50.60.50.4-0.40.40.40.30.5
Retroperitoneal fat weight1.65.26.0-2.3-2.32.42.42.5-2.42.22.02.12.2
Reaction time number correct0.10.20.50.50.3-0.4-0.3-0.70.7-0.2-0.2-0.3-0.4
Reaction time mean minus median2.53.34.3-2.1-2.02.01.82.0-2.01.61.41.51.6
Reaction time mean minus median AUC3.64.65.5-2.3-2.22.22.12.3-2.32.02.02.02.1
Reaction time num false alarms1.41.92.91.51.4-1.6-1.3-1.71.7-1.1-1.0-1.1-1.2
Reaction time num false alarms AUC1.11.52.51.31.2-1.3-1.1-1.51.6-1.0-1.0-1.1-1.2
Reaction time trials correct on left0.10.20.50.50.3-0.4-0.3-0.70.7-0.2-0.2-0.3-0.4
Reaction time trials on left0.10.10.40.30.2-0.2-0.2-0.50.6-0.1-0.1-0.2-0.3
Reaction time mean1.92.74.0-1.8-1.71.71.61.8-2.01.41.31.41.5
Reaction time mean AUC1.21.62.7-1.5-1.41.31.21.5-1.61.10.91.01.1
Median of all reaction times0.91.32.2-1.2-1.11.11.11.3-1.51.00.90.91.1
Reaction time omissions1.01.42.6-1.6-1.51.41.31.2-1.21.00.70.50.9
Reaction time false alarm rate0.30.40.70.60.6-0.6-0.5-0.70.8-0.6-0.6-0.5-0.7
Reaction time premature initiation rate2.12.94.2-2.0-2.01.91.81.6-1.51.71.51.41.3
Reaction time premature initiations1.82.63.7-1.9-1.91.81.71.4-1.31.71.51.41.3
Std. dev. reaction times3.65.06.4-2.4-2.42.42.22.5-2.52.01.91.92.0
Reaction time trials completed0.10.10.40.30.2-0.2-0.2-0.50.6-0.1-0.1-0.2-0.3
Reaction time trials AUC0.00.00.10.0-0.10.10.1-0.20.30.30.30.20.1
Run reversals in cocaine runway, females0.30.30.80.10.2-0.1-0.4-0.60.7-0.6-0.7-0.8-0.9
Run reversals in cocaine runway, males3.63.54.31.91.9-1.8-1.9-1.91.9-2.1-1.7-1.8-1.7
Latency to leave start box in cocaine runway0.10.10.20.30.2-0.0-0.1-0.20.3-0.2-0.5-0.5-0.5
Latency to leave start box in cocaine runway, F0.10.10.40.60.4-0.3-0.4-0.20.2-0.3-0.3-0.2-0.2
Latency to leave start box in cocaine runway, M0.20.20.5-0.7-0.60.60.70.4-0.30.50.10.00.0
Std. dev. time between licks in bursts0.30.30.9-0.10.00.1-0.1-0.30.6-0.5-0.9-0.9-0.9
Total sessions with >9 infusions0.40.40.91.00.9-0.9-0.7-0.50.3-0.10.50.50.3
Short access day 1 total inactive lever presses0.70.81.6-0.8-0.80.80.70.7-0.71.01.01.30.9
Short access day 10 total inactive lever presses1.21.32.01.01.1-1.1-1.0-1.21.1-1.1-1.2-1.4-1.0
Short access day 1 total infusions0.40.41.4-0.1-0.0-0.10.20.3-0.40.71.01.11.2
Short access day 10 total infusions0.70.81.31.11.1-0.9-1.0-1.01.1-0.6-0.2-0.2-0.8
Short access total infusions0.60.71.61.31.2-1.1-1.0-0.80.8-0.40.30.3-0.2
Short access day 1 locomotion0.40.41.20.20.3-0.30.10.4-0.80.50.80.91.1
Short access day 10 total locomotion0.20.20.40.50.7-0.5-0.6-0.50.5-0.4-0.1-0.1-0.3
Short access total locomotion0.91.01.71.11.3-1.1-1.2-1.11.1-0.9-0.4-0.4-0.7
One hour access (0.3 mA shock)1.11.32.11.31.4-1.4-1.3-1.21.0-1.1-0.9-0.6-0.7
Compulsive drug intake0.50.51.70.00.3-0.4-0.2-0.60.7-0.6-1.2-1.3-0.7
One hour access (shock baseline)0.10.10.30.60.5-0.5-0.5-0.20.0-0.20.20.50.2
Social response proportion0.10.10.30.10.1-0.1-0.2-0.10.1-0.3-0.4-0.5-0.1
Social responses1.01.31.80.91.1-0.9-1.1-1.21.2-1.1-1.3-1.3-1.3
Social time0.10.10.5-0.7-0.40.50.30.1-0.10.0-0.2-0.30.0
Soleus weight3.811.212.7-3.3-3.23.23.33.3-3.23.43.63.53.4
Bone: stiffness12.018.920.0-4.4-4.34.24.34.2-4.34.44.54.54.4
Tibialis anterior weight1.13.76.2-1.3-1.41.41.61.8-2.12.02.52.42.4
Time to tail flick, vehicle, before self-admin0.70.71.30.80.8-0.9-0.8-1.01.1-0.8-0.7-0.8-0.8
Time to tail flick, vehicle, after self-admin1.82.03.70.71.0-1.0-0.9-1.41.7-1.4-1.8-1.9-1.6
Time to tail flick, test, before self-admin0.00.00.1-0.10.1-0.0-0.0-0.10.3-0.2-0.2-0.3-0.2
Time to tail flick, test, after self-admin0.20.20.60.30.1-0.0-0.3-0.30.4-0.3-0.6-0.5-0.8
Delta time to tail flick, vehicle, before/after SA0.70.71.20.50.7-0.7-0.6-0.80.9-0.9-1.1-1.1-0.8
Delta time to tail flick, test, before/after SA0.10.10.1-0.1-0.30.30.20.3-0.40.30.10.30.1
Tibia length0.51.52.90.60.9-0.7-0.9-1.11.2-1.3-1.7-1.7-1.6
Ambulatory time before self-admin0.00.00.1-0.2-0.20.10.20.2-0.10.20.20.10.3
Ambulatory time after self-admin0.10.10.40.60.3-0.4-0.3-0.1-0.2-0.00.30.40.1
Bone: tissue strength0.80.81.0-0.9-1.00.91.00.8-0.60.90.80.80.8
Total heroin consumption0.00.10.2-0.1-0.0-0.30.20.1-0.20.20.10.00.5
Bone: trabecular number2.74.15.7-2.4-2.32.32.22.0-1.92.01.71.61.7
Bone: trabecular spacing0.60.81.31.11.1-1.1-1.0-0.90.7-0.9-0.6-0.5-0.6
Bone: trabecular thickness0.10.20.3-0.6-0.50.60.50.3-0.20.40.20.10.2
Bone: trabecular tissue density1.92.73.2-1.5-1.61.71.61.7-1.81.61.71.61.6
Water consumed over 24 hours0.00.00.10.30.2-0.2-0.2-0.20.10.00.00.1-0.0
Number of responses in last shaping day1.21.22.11.21.3-1.4-1.3-1.10.9-1.0-1.0-1.0-0.8