Hub : Genes

LOC120097381

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC gene expression LOC120097381 0.66 0.16 0.0e+00 0.23 0.25 0.35 0.29 2.9e-10 6.6e-11 1.2e-15 8.5e-13
2 RMTg gene expression LOC120097381 0.37 0.15 3.9e-07 0.11 0.14 0.11 0.14 7.2e-04 1.6e-04 9.8e-04 1.1e-04
3 IL gene expression LOC120097381 0.5 0.15 1.2e-11 0.34 0.39 0.38 0.38 5.1e-09 1.9e-10 5.9e-10 5.3e-10
4 PL gene expression LOC120097381 0.35 0.11 0.0e+00 0.33 0.39 0.39 0.4 9.7e-37 2.7e-45 1.1e-45 7.5e-46
5 Eye gene expression LOC120097381 0.43 0.18 1.4e-03 0.06 0.12 0.07 0.09 4.6e-02 6.3e-03 3.0e-02 1.7e-02
6 OFC gene expression LOC120097381 0.6 0.12 4.4e-15 0.39 0.51 0.44 0.51 2.8e-10 4.1e-14 7.1e-12 3.6e-14
7 Liver gene expression LOC120097381 0.27 0.1 0.0e+00 0.19 0.18 0.19 0.19 6.6e-21 4.6e-20 1.9e-20 2.0e-20
8 LHb gene expression LOC120097381 0.55 0.14 3.0e-13 0.45 0.39 0.4 0.42 3.5e-12 2.9e-10 1.3e-10 4.0e-11
9 pVTA gene expression LOC120097381 0.21 0.09 0.0e+00 0.23 0.25 0.23 0.23 2.1e-18 6.1e-20 1.6e-18 1.1e-18
10 BLA gene expression LOC120097381 0.12 0.07 4.1e-06 0.06 0.11 0.09 0.08 2.5e-04 3.2e-06 2.6e-05 4.8e-05
11 NAcc gene expression LOC120097381 0.32 0.12 0.0e+00 0.31 0.38 0.38 0.38 3.1e-48 2.3e-61 1.9e-61 2.2e-61
12 Brain gene expression LOC120097381 0.04 0.03 2.6e-03 0.03 0.03 0.03 0.03 8.3e-04 2.2e-03 1.2e-03 1.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density1.01.93.51.6-0.8-1.3-1.4-0.8-1.60.91.0-1.2-1.61.81.9
Area under the delay curve0.10.10.60.10.2-0.0-0.10.3-0.1-0.3-0.3-0.3-0.40.30.8
BMI with tail3.712.822.44.2-2.8-3.5-3.8-2.1-3.92.62.4-3.4-4.24.34.7
BMI without tail0.94.67.52.3-1.7-2.1-2.3-1.1-2.31.41.5-2.4-2.72.52.7
Body weight3.515.219.84.4-3.8-4.2-4.2-3.4-4.03.73.6-4.2-4.43.62.9
Weight adjusted by age0.51.62.61.4-1.4-1.4-1.2-1.6-1.21.41.4-1.2-1.11.00.1
Bone surface5.611.014.83.8-3.1-3.5-3.5-3.3-3.63.23.1-3.0-3.43.52.6
Bone volume2.55.07.62.7-1.8-2.2-2.4-2.0-2.51.81.8-1.8-2.22.82.5
Breakpoint value in progressive ratio session2.54.45.32.2-2.2-2.2-2.2-2.2-2.32.22.2-1.9-1.92.11.4
Number of licking bursts0.20.50.80.9-0.8-0.7-0.8-0.8-0.90.60.8-0.5-0.60.70.6
Context. condit. distance diff. score1.92.23.4-1.61.71.61.51.81.5-1.7-1.81.41.3-1.2-0.5
Locomotion velocity, session 10.10.10.6-0.40.10.10.30.20.3-0.1-0.0-0.20.0-0.8-0.8
Locomotion distance, session 10.81.12.01.1-0.7-1.0-1.1-0.4-1.20.70.8-1.3-1.41.01.3
Locomotion velocity, session 23.33.94.92.1-1.8-2.1-2.1-1.7-2.21.82.0-2.1-2.21.81.6
Locomotion distance, session 21.01.42.31.2-1.0-1.2-1.3-0.7-1.40.91.0-1.5-1.51.11.2
Locomotion velocity, session 30.10.10.60.10.20.00.00.6-0.1-0.3-0.3-0.1-0.30.10.7
Locomotion distance, session 30.00.00.1-0.1-0.00.10.10.20.0-0.0-0.10.10.1-0.2-0.0
Stereotopy head waving bouts, day 30.40.51.4-0.51.00.50.51.20.7-0.9-1.10.20.0-0.50.4
Stereotopy head waving duration, day 30.50.71.7-0.61.20.70.61.10.9-1.0-1.30.60.4-0.40.3
Locomotion velocity, session 70.30.42.30.20.60.1-0.20.7-0.3-0.7-0.50.0-0.30.71.5
Locomotion distance, session 70.10.10.30.10.1-0.1-0.20.4-0.2-0.0-0.1-0.5-0.50.10.5
Stereotopy head waving bouts, day 70.20.21.50.50.2-0.1-0.3-0.1-0.4-0.2-0.10.2-0.20.81.2
Stereotopy head waving duration, day 71.21.53.01.4-0.8-1.1-1.3-1.1-1.30.80.9-0.8-1.11.71.7
Locomotion velocity, session 80.60.71.30.6-1.1-0.9-0.6-0.8-0.61.11.1-1.1-0.8-0.2-0.7
Locomotion distance, session 80.10.20.6-0.10.60.20.10.70.1-0.6-0.60.2-0.10.00.7
Degree of sensitization distance0.10.10.40.30.0-0.3-0.40.2-0.30.00.0-0.5-0.60.30.7
Degree of sensitization stereotypy0.91.12.21.2-0.8-0.9-1.1-1.0-1.20.70.8-0.5-0.81.51.5
Conditioned locomotion1.41.62.21.3-1.4-1.4-1.2-1.4-1.21.51.4-1.5-1.40.80.4
Cocaine response after cond. corrected1.21.82.8-1.51.41.41.51.71.4-1.4-1.31.01.0-1.5-0.9
Cocaine response after cond. not corrected0.91.32.0-1.21.21.11.31.41.2-1.2-1.10.80.9-1.3-0.8
Cocaine response before conditioning0.91.01.51.1-1.1-1.0-1.1-1.2-1.11.11.0-0.7-0.71.10.7
Saline control response3.54.86.62.1-2.5-2.4-2.1-2.3-2.12.52.6-2.6-2.31.30.3
Bone: connectivity density3.45.46.72.6-2.1-2.4-2.4-1.9-2.52.22.1-2.3-2.62.52.0
Bone: cortical apparent density0.00.10.1-0.1-0.3-0.0-0.2-0.3-0.10.40.4-0.10.10.0-0.3
Bone: cortical area0.81.31.81.3-1.3-1.2-1.1-1.3-1.31.11.3-0.9-1.00.90.5
Bone: cortical porosity0.30.30.60.7-0.4-0.6-0.6-0.4-0.50.30.3-0.6-0.70.80.6
Bone: cortical porosity0.70.81.11.0-0.8-1.0-1.0-0.8-0.80.70.6-1.0-1.11.00.7
Bone: cortical thickness2.13.47.01.4-2.6-1.9-1.5-2.2-1.82.22.6-2.0-1.50.6-0.6
Bone: cortical thickness0.30.41.1-0.0-1.0-0.4-0.2-0.5-0.30.81.0-0.8-0.3-0.5-1.1
Bone: cortical tissue density0.10.10.30.0-0.5-0.2-0.3-0.5-0.30.50.5-0.2-0.00.1-0.3
Condit. Reinf. active minus inactive responses0.20.30.50.4-0.3-0.5-0.6-0.3-0.70.30.5-0.6-0.60.60.7
Condit. Reinf. active-inactive response ratio0.00.00.1-0.10.1-0.0-0.2-0.1-0.2-0.10.2-0.1-0.10.20.2
Condit. Reinf. active responses0.20.30.90.5-0.2-0.4-0.5-0.1-0.70.10.4-0.3-0.50.71.0
Condit. Reinf. inactive responses0.10.10.80.50.1-0.1-0.20.2-0.4-0.2-0.10.1-0.30.50.9
Incentive salience index mean0.60.81.50.9-0.6-0.8-1.0-0.4-1.10.50.7-0.9-1.11.11.2
Condit. Reinf. lever presses0.91.32.01.4-0.9-1.1-1.3-0.8-1.30.80.8-0.9-1.21.41.4
Condit. Reinf. active minus inactive responses0.00.10.30.20.20.1-0.1-0.1-0.2-0.1-0.10.40.20.50.6
Condit. Reinf. active-inactive response ratio0.20.31.0-0.00.80.50.30.50.2-0.8-0.71.00.50.20.7
Condit. Reinf. active responses0.30.51.30.7-0.4-0.5-0.8-0.6-0.80.50.5-0.3-0.51.11.0
Condit. Reinf. inactive responses0.50.71.10.7-0.8-0.8-1.0-0.7-0.90.90.8-1.1-0.91.00.6
Condit. Reinf. lever presses2.63.75.02.2-1.9-1.9-2.1-2.1-2.21.82.0-1.5-1.72.11.6
Condit. Reinf. lever reinforcers received0.60.81.71.0-0.7-0.8-1.0-0.9-1.00.80.8-0.6-0.71.31.0
Conditioned reinforcement - actives0.00.10.40.3-0.0-0.10.1-0.6-0.0-0.10.10.60.30.3-0.1
Conditioned reinforcement - inactives1.33.46.6-1.82.02.01.91.51.8-1.9-1.92.62.3-1.1-0.8
Conditioned locomotion6.810.114.3-3.33.33.43.32.93.3-3.3-3.33.83.6-2.5-1.7
Patch foraging indifference point 0 sec0.00.00.1-0.10.00.1-0.00.10.10.1-0.20.10.00.10.2
Patch foraging indifference point AUC1.23.04.91.7-2.0-1.8-1.8-2.2-1.81.82.0-1.4-1.41.50.8
Delay disc. indifference point, 0s delay0.30.40.9-0.30.90.30.10.90.6-1.0-0.90.0-0.2-0.10.9
Delay disc. indifference point, 16s delay0.30.40.7-0.50.80.70.40.80.2-0.8-0.80.80.6-0.00.8
Delay disc. indifference point, 2s delay0.10.10.2-0.10.40.20.10.40.1-0.5-0.40.20.00.10.4
Delay disc. indifference point, 24s delay0.10.20.4-0.60.30.40.50.40.5-0.3-0.30.10.3-0.6-0.6
Delay disc. indifference point, 4s delay0.10.10.4-0.30.30.20.20.60.3-0.5-0.5-0.2-0.2-0.20.2
Delay disc. indifference point, 8s delay0.00.10.2-0.10.20.10.10.40.3-0.3-0.4-0.3-0.3-0.10.2
Indifference point function ln k3.911.716.3-3.63.63.63.74.03.6-3.5-3.73.03.0-3.2-2.0
Indifference point function log k3.911.716.3-3.63.63.63.74.03.6-3.5-3.73.03.0-3.2-2.0
Patch foraging total patch changes 0 sec0.00.00.2-0.3-0.00.10.10.10.20.2-0.1-0.00.1-0.3-0.4
Patch foraging total patch changes 12 sec4.96.68.02.6-2.8-2.7-2.8-2.6-2.82.62.8-2.5-2.52.41.6
Patch foraging total patch changes 18 sec0.51.11.61.0-0.9-1.1-1.2-1.0-1.30.91.1-0.9-1.01.10.9
Patch foraging total patch changes 24 sec0.62.13.21.3-1.8-1.6-1.4-1.8-1.31.81.7-1.5-1.30.9-0.0
Patch foraging total patch changes 6 sec1.01.72.61.1-1.5-1.3-1.3-1.1-1.51.51.6-1.5-1.30.90.5
Patch foraging time to switch 0 sec1.45.38.92.7-1.7-2.2-2.5-1.7-2.51.71.6-1.9-2.42.93.0
Patch foraging water rate 0 sec2.69.812.2-3.52.73.23.32.63.5-2.7-2.73.03.4-3.5-3.3
Patch foraging water rate 12 sec4.819.424.7-4.94.04.54.94.14.9-3.9-3.93.94.4-5.0-4.4
Patch foraging water rate 18 sec2.65.88.2-2.72.32.42.72.52.5-2.2-1.92.02.2-2.9-2.4
Patch foraging water rate 24 sec6.18.711.6-3.12.83.03.22.73.4-2.7-2.82.62.9-3.3-2.8
Patch foraging water rate 6 sec6.69.814.7-3.52.63.13.53.03.5-2.7-2.52.53.0-3.8-3.5
Seeking ratio, delayed vs. immediate footshock0.10.10.70.10.10.2-0.10.4-0.1-0.2-0.40.1-0.00.40.8
Distance traveled before self-admin0.61.42.81.5-0.9-1.1-1.3-1.1-1.20.90.8-0.8-1.11.71.5
Distance traveled after self-admin0.20.30.70.6-0.7-0.5-0.7-0.7-0.60.60.5-0.4-0.40.80.4
Extensor digitorum longus weight7.831.236.85.9-6.0-6.1-5.8-5.7-5.85.85.9-5.9-5.94.62.9
Bone: elastic displacement1.92.45.2-1.80.71.51.81.21.7-1.1-0.91.11.5-2.3-2.3
Bone: elastic work0.60.82.00.4-1.4-0.8-0.4-0.7-0.61.11.2-1.2-0.7-0.3-0.9
Bone: endosteal estimation0.30.82.0-0.01.30.60.41.20.4-1.1-1.40.70.10.31.4
Bone: endosteal perimeter0.41.12.50.01.50.70.41.20.4-1.4-1.51.10.30.61.6
Epididymis fat weight1.89.313.6-2.63.53.23.13.13.2-3.6-3.73.63.1-2.0-0.8
Delta time in closed arm before/after self-admin0.20.20.6-0.2-0.3-0.2-0.00.20.00.30.3-0.8-0.5-0.6-0.6
Delta time in open arm before/after self-admin0.30.30.90.8-0.5-0.5-0.6-0.9-0.40.50.30.0-0.10.90.5
Diff in mean of infusions in LGA sessions0.30.50.90.6-0.9-0.7-0.6-0.8-0.80.91.0-0.7-0.60.4-0.1
Delay discount exponential model param0.10.10.4-0.1-0.10.10.1-0.20.10.20.20.30.4-0.3-0.6
Extinction: sum of active levers before priming2.64.05.32.1-1.9-2.0-2.2-1.8-2.31.81.9-1.9-2.02.21.8
Active lever presses in extinction session 63.33.34.92.2-1.9-2.0-1.9-2.2-1.81.81.8-1.6-1.71.60.9
Bone: final force2.74.45.42.3-2.1-2.3-2.2-2.2-2.22.32.2-2.1-2.21.81.2
Bone: final moment2.54.04.92.2-2.0-2.2-2.1-2.0-2.12.22.1-2.0-2.11.71.1
Food consumed during 24 hour testing period0.00.10.3-0.0-0.10.00.1-0.50.10.10.20.30.4-0.2-0.5
Glucose1.52.45.0-1.22.11.51.32.21.3-2.1-2.11.40.9-0.50.6
Heart weight0.61.03.3-0.61.30.80.71.80.7-1.5-1.30.3-0.1-0.31.0
Delay discount hyperbolic model param0.10.10.5-0.1-0.10.10.1-0.20.10.20.20.30.4-0.3-0.7
Intermittent access intake day 1-15 change0.31.83.4-1.31.41.41.30.91.3-1.3-1.31.91.7-1.0-0.8
Intermittent access intake escalation0.31.53.1-1.21.21.31.20.71.2-1.1-1.21.81.6-0.9-0.8
Intermittent access intake escalation 20.81.32.7-1.11.21.21.10.71.2-1.0-1.21.71.5-0.8-0.7
Intermitt. access day 1 inactive lever presses0.00.20.4-0.60.50.50.40.30.3-0.4-0.40.60.6-0.2-0.2
Intermitt. access day 15 inactive lever presses0.31.63.5-1.11.61.41.31.20.9-1.6-1.21.91.5-0.5-0.0
Intermitt. access escalation Index1.13.45.0-1.82.22.01.72.21.9-2.2-2.11.81.7-1.3-0.5
Intermittent access day 1 total infusions0.61.94.1-0.72.01.31.01.80.8-2.0-1.71.60.90.01.2
Intermittent access day 15 total infusions2.25.49.8-2.02.82.52.32.32.0-2.9-2.43.12.5-1.3-0.4
Intermittent access terminal intake (last 3 days)2.23.97.7-1.52.52.11.92.01.6-2.6-2.22.82.0-0.80.1
Intermittent access total infusions2.22.65.3-1.12.21.71.51.81.1-2.3-1.72.21.5-0.50.5
Intermittent access day 1 locomotion0.81.53.2-0.81.71.20.91.60.8-1.8-1.41.50.9-0.20.7
Intermittent access day 15 total locomotion1.03.88.1-1.62.42.11.91.91.5-2.4-2.12.92.2-0.70.1
Intermittent access total locomotion4.15.09.8-1.62.92.42.02.41.7-3.0-2.63.12.2-0.60.7
Intermittent access standard deviation0.42.23.2-1.61.61.51.61.21.5-1.5-1.31.81.7-1.2-1.0
Left kidney weight0.32.24.4-1.02.01.51.21.71.4-2.0-2.11.61.1-0.50.5
Right kidney weight0.21.42.4-1.01.31.21.21.11.4-1.4-1.61.41.1-0.9-0.5
Cocaine induced anxiety0.00.10.20.4-0.3-0.3-0.3-0.4-0.30.20.1-0.0-0.10.50.3
Post-drug Anxiety0.80.91.61.2-1.2-1.0-0.9-1.1-1.01.00.9-0.8-0.80.90.5
Baseline Anxiety0.20.30.60.3-0.7-0.5-0.4-0.4-0.30.70.7-0.8-0.5-0.2-0.4
Tail length0.10.81.60.3-1.0-0.9-0.7-1.1-0.51.01.3-1.2-0.7-0.2-1.0
Length with tail1.46.09.32.2-2.9-2.7-2.3-2.8-2.22.93.1-2.9-2.41.0-0.2
Length without tail0.94.67.61.9-2.7-2.4-1.8-2.4-1.82.82.7-2.6-2.10.6-0.6
Times rat made contact with spout0.40.50.80.5-0.6-0.7-0.7-0.6-0.80.60.8-0.9-0.70.60.5
Lifetime Intake1.51.93.9-1.01.91.41.31.70.9-2.0-1.41.71.2-0.50.4
Liver weight, left1.01.82.5-1.31.41.31.41.41.5-1.3-1.31.11.1-1.6-1.1
Liver weight, right2.64.66.3-2.32.22.12.32.52.3-2.1-2.11.71.7-2.4-1.7
Locomotor activity3.14.87.9-2.61.72.22.52.22.3-1.8-1.51.82.1-2.8-2.4
Locomotor testing distance2.66.410.7-3.01.92.52.92.52.8-2.2-1.81.92.4-3.3-2.8
Locomotor testing rearing1.55.47.5-2.72.02.42.72.42.5-2.2-1.81.82.1-2.7-2.4
Locomotion in novel chamber4.56.07.9-2.32.82.62.52.52.5-2.7-2.82.82.5-1.9-1.0
Locomotion in novel chamber post-restriction1.23.65.6-1.82.22.11.91.91.8-2.2-2.12.42.1-1.2-0.4
Fecal boli incidents, locomotor time 10.10.20.60.5-0.1-0.2-0.3-0.6-0.40.00.20.30.10.70.7
Change in fecal boli incidents, locomotor task0.10.10.2-0.10.0-0.00.10.50.20.1-0.2-0.4-0.4-0.4-0.1
Time >=10cm from walls, locomotor time 10.40.52.50.40.70.2-0.10.50.1-0.8-0.90.70.00.81.6
Bouts of movement, locomotor time 11.11.52.91.2-1.5-1.2-1.3-1.7-1.01.41.2-1.0-0.81.30.4
Total resting periods, locomotor time 11.01.12.21.1-1.2-1.0-1.2-1.5-0.91.21.0-0.7-0.61.30.6
Rest time, locomotor task time 11.11.82.5-1.31.41.41.41.11.4-1.4-1.31.61.5-1.1-0.9
Distance moved, locomotor task time 10.10.41.10.7-0.3-0.6-0.7-0.1-0.70.40.4-0.7-0.80.71.0
Vertical activity count, locomotor time 10.11.01.4-1.11.11.11.01.20.9-1.0-1.01.01.0-0.9-0.5
Time >=10cm from walls, locomotor time 20.10.20.80.6-0.1-0.4-0.5-0.6-0.10.1-0.1-0.0-0.20.90.7
Bouts of movement, locomotor time 20.20.60.90.7-0.8-0.7-0.9-0.9-0.80.90.7-0.7-0.61.00.7
Total resting periods, locomotor time 20.10.40.80.6-0.5-0.5-0.7-0.6-0.60.60.4-0.4-0.40.90.8
Rest time, locomotor task time 21.52.53.6-1.41.91.71.61.71.6-1.8-1.81.71.4-1.1-0.4
Distance moved, locomotor task time 20.81.11.71.0-1.2-1.1-1.1-1.2-1.01.21.3-1.2-1.00.60.0
Vertical activity count, locomotor time 20.20.63.0-0.8-0.10.40.60.20.6-0.00.00.20.6-1.3-1.7
Light reinforcement 10.10.20.5-0.70.30.50.50.30.5-0.4-0.20.40.6-0.6-0.7
Light reinforcement 20.30.82.0-0.60.90.90.90.50.9-1.1-0.91.41.1-0.5-0.2
Bone: marrow area0.40.92.3-0.11.30.60.41.30.5-1.1-1.50.70.10.31.4
Bone: maximum diameter0.20.41.11.0-0.6-0.7-0.7-0.9-0.70.60.4-0.2-0.50.70.6
Bone: maximum force4.18.111.03.3-2.6-3.0-3.0-2.6-3.22.62.7-2.6-3.03.02.4
Bone: maximum moment3.97.39.93.1-2.5-2.9-2.9-2.5-3.02.52.5-2.5-2.92.82.3
Mean time between licks in bursts0.00.30.8-0.1-0.6-0.3-0.1-0.1-0.10.60.6-0.8-0.4-0.6-0.9
Mean num. licks in bursts0.10.30.6-0.80.70.60.70.70.6-0.5-0.60.30.4-0.5-0.4
Cd content in liver0.91.02.4-0.81.21.10.90.80.8-1.1-1.11.51.3-0.30.1
Co content in liver2.83.35.0-2.21.41.81.91.52.1-1.3-1.41.31.8-2.2-2.2
Cu content in liver0.10.10.80.2-0.0-0.1-0.20.1-0.5-0.10.1-0.1-0.10.70.9
Fe content in liver0.10.10.30.2-0.5-0.3-0.1-0.3-0.10.40.5-0.3-0.2-0.4-0.5
K content in liver0.70.71.20.9-0.7-0.9-0.8-0.4-0.90.70.7-1.0-1.10.70.9
Mg content in liver0.20.20.8-0.50.60.50.50.90.4-0.6-0.60.20.2-0.40.2
Mn content in liver3.54.05.12.2-2.2-2.1-2.0-2.3-2.12.12.2-1.8-1.81.71.0
Na content in liver0.20.30.60.4-0.7-0.5-0.3-0.8-0.20.70.6-0.4-0.3-0.1-0.5
Rb content in liver1.82.13.4-1.61.61.61.61.91.4-1.6-1.51.21.3-1.3-0.5
Se content in liver0.10.10.40.00.20.30.20.10.0-0.4-0.20.60.40.10.2
Sr content in liver2.01.73.21.2-1.6-1.4-1.3-1.8-1.11.61.6-1.2-1.00.8-0.1
Zn content in liver0.30.30.50.5-0.5-0.6-0.6-0.4-0.60.50.5-0.7-0.60.70.5
Bone: minimum diameter0.40.73.20.21.00.40.11.1-0.1-1.0-1.10.5-0.10.91.8
Time in familiar zone, hab. session 10.10.10.3-0.20.60.30.20.60.1-0.5-0.30.30.20.10.5
Time in novel zone, hab. session 10.70.82.3-1.00.40.70.90.61.1-0.4-0.60.40.7-1.4-1.5
Total zone transitions, hab. session 10.91.31.91.1-1.0-1.1-1.2-1.0-1.41.01.1-1.0-1.11.31.2
Total locomotion distance, hab. session 10.20.20.6-0.10.70.30.10.60.2-0.6-0.80.30.00.20.8
Locomotion velocity, hab. session 10.10.10.80.30.2-0.2-0.30.1-0.3-0.1-0.2-0.1-0.40.60.9
Time in familiar zone, hab. session 20.30.41.6-0.70.10.30.60.40.60.0-0.0-0.10.3-1.2-1.3
Time in novel zone, hab. session 20.30.41.30.7-0.3-0.4-0.6-0.4-0.60.20.1-0.3-0.51.11.2
Total zone transitions, hab. session 22.63.35.12.0-1.3-1.8-2.0-1.1-2.01.31.3-1.9-2.22.12.3
Total locomotion distance, hab. session 20.40.52.20.60.2-0.4-0.60.3-0.6-0.1-0.2-0.6-0.90.91.5
Locomotion velocity, hab. session 20.30.52.50.60.3-0.3-0.50.4-0.5-0.3-0.4-0.4-0.80.91.6
Novel to familiar place preference ratio1.41.83.41.6-1.1-1.3-1.5-1.5-1.51.11.1-0.8-1.11.81.5
Novelty place preference0.81.02.31.2-0.7-0.9-1.1-1.1-1.10.70.7-0.4-0.71.51.3
Time in novel zone, NPP test0.60.71.61.0-0.6-0.7-1.0-0.9-0.90.60.6-0.4-0.61.31.1
Total zone transitions, NPP test2.94.35.32.3-1.9-2.2-2.3-1.8-2.21.91.8-2.1-2.32.11.8
Total locomotion distance, NPP test0.30.41.20.7-0.2-0.5-0.7-0.0-0.60.20.1-0.7-0.90.81.1
Locomotion velocity, NPP test0.40.51.50.8-0.3-0.6-0.8-0.2-0.70.30.2-0.7-0.91.01.2
Intraocular pressure1.21.93.6-1.41.31.41.40.71.5-1.2-1.41.91.8-1.1-1.0
Delta distance traveled before/after self-admin0.50.51.7-1.00.20.70.80.60.6-0.3-0.30.30.7-1.1-1.3
Delta ambulatory time before/after self-admin0.20.31.4-0.80.00.40.50.40.4-0.1-0.00.10.4-0.9-1.2
Parametrial fat weight2.66.111.3-2.13.02.62.22.82.5-3.0-3.42.82.2-1.30.1
Pavlov. Cond. lever latency0.50.60.9-0.90.70.80.90.50.8-0.5-0.50.80.9-0.9-0.9
Pavlov. Cond. magazine entry latency0.91.13.11.2-0.4-0.9-1.2-0.6-1.10.50.4-0.8-1.11.61.8
Pavlov. Cond. change in total contacts0.70.72.51.0-0.3-0.6-0.9-0.6-0.90.30.3-0.2-0.51.61.5
Pavlov. Cond. index score0.40.51.00.9-0.5-0.7-0.8-0.7-0.80.50.4-0.5-0.61.00.9
Pavlov. Cond. latency score0.30.40.80.8-0.4-0.6-0.7-0.5-0.60.30.3-0.5-0.70.90.9
Pavlov. Cond. lever contacts0.30.30.60.7-0.4-0.5-0.6-0.2-0.60.30.2-0.6-0.70.70.8
Pavlov. Cond. magazine entry number0.40.61.1-0.80.60.70.90.90.8-0.6-0.60.40.5-1.0-0.8
Pavlov. Cond. intertrial magazine entries0.50.61.4-0.80.60.90.90.60.6-0.8-0.41.11.2-0.6-0.6
Pavlov. Cond. lever-magazine prob. diff.0.70.91.81.1-0.7-0.9-1.1-0.9-1.00.70.6-0.7-0.91.31.2
Pavlov. Cond. response bias0.30.40.90.8-0.6-0.6-0.8-0.7-0.70.50.5-0.4-0.50.90.7
Pavlov. Cond. lever latency0.71.01.5-1.21.01.01.11.21.1-0.9-1.00.60.8-1.0-0.7
Pavlov. Cond. magazine entry latency4.86.88.52.8-2.6-2.7-2.8-2.6-2.92.42.7-2.4-2.52.72.1
Pavlov. Cond. change in total contacts1.64.06.12.3-1.8-1.9-2.2-2.1-2.31.61.8-1.2-1.62.52.2
Pavlov. Cond. index score3.04.76.12.5-2.1-2.2-2.4-2.3-2.51.92.2-1.7-2.02.42.0
Pavlov. Cond. latency score2.64.15.52.3-1.9-2.0-2.2-2.1-2.31.72.0-1.6-1.82.21.9
Pavlov. Cond. lever contacts0.71.01.61.2-1.0-1.0-1.1-1.3-1.10.91.1-0.6-0.81.00.8
Pavlov. Cond. magazine entry number8.210.712.9-3.53.33.43.53.53.6-3.2-3.43.03.0-3.4-2.4
Pavlov. Cond. intertrial magazine entries0.71.51.9-1.21.41.31.21.21.3-1.2-1.41.31.3-1.1-0.7
Pavlov. Cond. lever-magazine prob. diff.3.65.57.12.6-2.3-2.4-2.5-2.5-2.72.12.4-1.9-2.12.62.0
Pavlov. Cond. response bias2.73.74.82.2-1.8-2.0-2.1-2.1-2.11.72.0-1.6-1.82.01.6
Time in closed arm before self-admin0.10.20.40.10.40.30.10.20.3-0.5-0.70.70.30.30.7
Time in closed arm after self-admin0.20.20.6-0.50.40.50.40.70.5-0.4-0.60.40.4-0.5-0.2
Time in open arm before self-admin0.70.82.2-1.30.70.70.91.10.8-0.6-0.3-0.10.4-1.5-1.3
Time in open arm after self-admin0.00.00.2-0.1-0.2-0.10.0-0.20.20.10.1-0.3-0.1-0.2-0.4
Bone: periosteal estimation0.20.41.50.9-0.1-0.5-0.5-0.2-0.60.1-0.0-0.1-0.60.91.2
Bone: periosteal perimeter0.30.71.41.1-0.5-0.8-0.8-0.6-0.90.40.4-0.5-0.81.11.2
Bone: post-yield work3.66.120.63.0-0.7-2.0-2.6-1.0-2.80.90.9-1.4-2.53.84.5
Progressive ratio test 1 active lever presses0.10.20.6-0.30.70.40.40.30.2-0.7-0.30.70.50.00.1
Progressive ratio test 1 breakpoint0.10.20.5-0.30.70.40.40.20.2-0.6-0.20.70.40.10.1
Progressive ratio test 1 inactive lever presses0.00.10.2-0.40.40.30.30.10.2-0.3-0.20.50.40.1-0.0
Progressive ratio test 2 active lever presses1.52.14.3-1.21.91.51.41.31.2-1.8-1.42.11.6-0.6-0.2
Progressive ratio test 2 breakpoint1.62.14.4-1.31.91.51.51.31.2-1.8-1.42.11.7-0.7-0.3
Progressive ratio test 2 inactive lever presses2.68.213.6-2.63.33.12.92.82.7-3.4-3.23.73.1-1.6-0.6
Incentive Sensitization - Responses0.10.10.60.50.1-0.2-0.3-0.1-0.5-0.10.10.1-0.20.60.8
Incentive Sensitization - Breakpoint0.00.10.50.20.30.0-0.10.1-0.3-0.3-0.10.40.00.50.7
Sum of active levers in priming session hrs 5-60.90.93.20.9-1.2-0.8-0.7-1.8-0.81.21.3-0.00.00.5-0.6
Progressive ratio1.13.37.32.2-1.1-1.8-1.9-1.1-1.81.11.0-1.6-2.12.32.7
Food seeking constrained by brief footshock0.10.10.20.0-0.4-0.2-0.1-0.1-0.30.40.4-0.3-0.2-0.2-0.2
Seeking ratio, punishment vs. effort1.73.86.9-2.41.31.92.11.71.9-1.3-1.21.52.0-2.5-2.6
Retroperitoneal fat weight8.538.247.5-6.26.86.66.46.86.4-6.9-6.96.35.9-5.1-2.7
Reaction time number correct0.10.20.60.1-0.5-0.4-0.2-0.6-0.20.50.7-0.4-0.2-0.4-0.8
Reaction time mean minus median0.95.77.82.8-2.4-2.5-2.5-2.7-2.42.32.1-2.0-2.22.61.9
Reaction time mean minus median AUC0.42.43.81.8-1.7-1.7-1.5-2.0-1.51.61.6-1.3-1.41.40.8
Reaction time num false alarms0.50.92.2-1.30.60.90.91.21.0-0.6-0.50.30.6-1.5-1.3
Reaction time num false alarms AUC0.10.20.8-0.6-0.10.20.30.50.30.10.1-0.30.0-0.9-0.9
Reaction time trials correct on left0.10.20.60.1-0.5-0.4-0.2-0.6-0.20.50.7-0.4-0.2-0.4-0.8
Reaction time trials on left0.10.30.70.2-0.6-0.5-0.3-0.7-0.30.60.8-0.5-0.3-0.4-0.8
Reaction time mean0.10.20.60.6-0.3-0.4-0.6-0.6-0.30.3-0.0-0.0-0.20.80.8
Reaction time mean AUC0.10.31.00.6-0.2-0.3-0.6-0.6-0.30.3-0.10.0-0.20.91.0
Median of all reaction times0.10.10.4-0.00.40.2-0.10.00.3-0.3-0.60.50.30.30.6
Reaction time omissions1.72.73.61.9-1.9-1.8-1.7-1.9-1.61.61.6-1.6-1.61.61.0
Reaction time false alarm rate0.30.41.1-0.90.40.70.61.00.7-0.5-0.50.20.4-1.0-0.6
Reaction time premature initiation rate1.52.34.91.2-1.9-1.7-1.3-1.5-1.21.81.9-2.2-1.70.4-0.4
Reaction time premature initiations1.23.66.41.4-2.3-2.1-1.6-2.1-1.52.32.5-2.5-1.90.4-0.7
Std. dev. reaction times0.51.72.61.6-1.4-1.4-1.4-1.6-1.21.30.9-0.9-1.11.51.1
Reaction time trials completed0.10.30.70.2-0.6-0.5-0.3-0.7-0.30.60.8-0.5-0.3-0.4-0.8
Reaction time trials AUC0.10.20.70.1-0.4-0.3-0.1-0.5-0.10.40.6-0.4-0.2-0.5-0.8
Run reversals in cocaine runway, females0.60.71.60.7-0.5-0.8-0.90.0-0.90.50.5-1.2-1.30.71.1
Run reversals in cocaine runway, males1.11.23.2-1.20.61.01.20.61.1-0.5-0.50.91.2-1.5-1.8
Latency to leave start box in cocaine runway0.20.21.30.40.1-0.1-0.30.3-0.4-0.2-0.1-0.0-0.30.71.2
Latency to leave start box in cocaine runway, F0.10.20.90.30.2-0.1-0.20.2-0.3-0.2-0.1-0.0-0.20.71.0
Latency to leave start box in cocaine runway, M0.20.10.40.5-0.4-0.3-0.3-0.0-0.60.20.3-0.2-0.40.30.5
Std. dev. time between licks in bursts0.20.51.9-0.70.10.40.70.60.8-0.1-0.2-0.10.2-1.2-1.4
Total sessions with >9 infusions0.20.21.00.60.1-0.3-0.40.1-0.6-0.20.2-0.2-0.50.71.0
Short access day 1 total inactive lever presses1.22.43.5-1.71.71.71.61.91.4-1.7-1.61.71.5-1.3-0.5
Short access day 10 total inactive lever presses0.10.81.6-1.30.90.90.91.00.7-0.8-0.60.70.8-1.0-0.6
Short access day 1 total infusions0.61.22.4-0.81.41.10.91.50.8-1.5-1.31.10.7-0.40.5
Short access day 10 total infusions0.30.63.30.40.80.0-0.20.7-0.7-0.8-0.20.3-0.31.01.8
Short access total infusions0.20.31.00.00.80.30.10.8-0.2-0.9-0.30.4-0.10.31.0
Short access day 1 locomotion0.71.22.3-1.11.41.21.11.40.7-1.5-1.01.31.0-0.60.1
Short access day 10 total locomotion0.20.71.6-0.51.30.80.61.00.4-1.2-0.91.10.60.10.8
Short access total locomotion0.61.02.2-0.71.41.00.81.20.5-1.5-1.01.30.8-0.10.6
One hour access (0.3 mA shock)6.27.39.8-2.73.12.92.82.82.6-3.0-2.83.12.8-2.1-1.0
Compulsive drug intake0.81.23.00.5-1.4-1.0-0.8-1.0-0.61.61.3-1.7-1.1-0.2-0.9
One hour access (shock baseline)2.87.412.6-2.43.22.92.72.72.5-3.3-2.93.52.9-1.5-0.4
Social response proportion0.70.81.31.0-1.0-0.9-1.0-1.1-0.91.10.8-0.7-0.80.90.6
Social responses0.10.20.40.2-0.6-0.4-0.2-0.5-0.30.60.6-0.4-0.2-0.1-0.4
Social time0.20.20.50.2-0.6-0.5-0.2-0.6-0.30.60.7-0.6-0.4-0.3-0.6
Soleus weight4.112.114.9-3.53.83.73.63.83.6-3.9-3.83.63.4-2.9-1.5
Bone: stiffness3.35.98.22.9-2.1-2.5-2.7-2.3-2.72.22.1-2.1-2.52.82.3
Tibialis anterior weight9.030.843.05.7-6.6-6.1-5.6-6.4-5.46.36.4-5.7-5.33.71.3
Time to tail flick, vehicle, before self-admin0.30.40.90.8-0.3-0.7-0.7-0.5-0.50.30.3-0.6-0.80.80.9
Time to tail flick, vehicle, after self-admin0.61.32.91.3-0.5-1.2-1.2-0.4-1.10.60.5-1.4-1.71.21.7
Time to tail flick, test, before self-admin1.11.33.4-1.01.61.21.01.80.8-1.5-1.20.90.6-0.70.5
Time to tail flick, test, after self-admin0.00.00.20.3-0.1-0.2-0.2-0.4-0.00.20.10.0-0.10.1-0.0
Delta time to tail flick, vehicle, before/after SA0.50.51.00.7-0.5-0.7-0.7-0.3-0.80.60.5-0.9-1.00.60.8
Delta time to tail flick, test, before/after SA0.91.13.80.8-1.4-1.0-0.7-1.9-0.41.41.1-0.6-0.20.2-1.1
Tibia length1.13.05.92.1-1.8-1.8-1.8-2.4-1.81.81.9-0.9-1.11.71.0
Ambulatory time before self-admin0.41.22.71.4-0.7-1.0-1.2-1.1-1.20.80.7-0.5-0.91.71.5
Ambulatory time after self-admin0.10.10.5-0.00.30.3-0.10.2-0.1-0.3-0.40.50.30.60.7
Bone: tissue strength0.00.00.10.20.0-0.1-0.2-0.1-0.20.10.1-0.0-0.10.40.4
Total heroin consumption5.46.47.72.6-2.7-2.7-2.7-2.8-2.62.72.7-2.5-2.42.31.3
Bone: trabecular number1.42.64.41.9-1.2-1.5-1.7-1.3-1.91.21.3-1.2-1.62.12.0
Bone: trabecular spacing0.71.01.6-1.30.91.01.01.01.1-0.9-0.80.60.8-1.2-0.9
Bone: trabecular thickness0.10.20.6-0.10.60.40.20.60.0-0.5-0.50.40.20.40.8
Bone: trabecular tissue density3.66.47.9-2.62.72.72.62.42.6-2.6-2.62.82.7-2.1-1.3
Water consumed over 24 hours0.50.91.60.8-1.1-1.0-0.9-1.2-1.01.11.3-1.1-0.80.60.2
Number of responses in last shaping day0.10.10.4-0.50.10.20.30.20.4-0.1-0.10.00.2-0.5-0.6