LOC120096689

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS XM_039092875.1 0.04 0.02 1.1e-03 0.01 0.02 0.02 0.01 5.6e-02 1.8e-03 2.0e-03 1.4e-02
2 Adipose alternative TSS XM_039092874.1 0.04 0.03 8.8e-04 0 0.02 0.02 0.01 8.1e-02 1.7e-03 2.4e-03 1.5e-02
3 Adipose gene expression LOC120096689 0.42 0.1 0.0e+00 0.27 0.41 0.4 0.41 2.9e-30 1.1e-48 1.4e-47 1.7e-48
4 Adipose isoform ratio XR_005493478.1 0.14 0.06 2.5e-13 0.12 0.11 0.11 0.11 4.7e-13 2.4e-12 3.6e-12 2.5e-12
5 Adipose mRNA stability LOC120096689 0.21 0.08 0.0e+00 0.16 0.17 0.16 0.16 2.0e-17 4.6e-18 1.8e-17 7.9e-18
6 pVTA gene expression LOC120096689 0.11 0.06 3.9e-03 0.01 0.04 -0.01 0.03 1.4e-01 1.2e-02 9.5e-01 1.7e-02
7 Adipose isoform ratio XR_005493474.1 0.16 0.07 2.8e-13 0.12 0.13 0.12 0.12 3.2e-13 7.6e-14 2.5e-13 1.6e-13
8 PL gene expression LOC120096689 0.15 0.06 1.8e-12 0.07 0.12 0.13 0.13 1.8e-08 2.0e-13 1.0e-13 5.5e-14
9 Brain gene expression LOC120096689 0.17 0.06 1.2e-12 0.11 0.16 0.15 0.15 2.9e-10 2.6e-14 1.2e-13 5.3e-14
10 NAcc alternative TSS XM_039092875.1 0.05 0.02 7.9e-04 0.01 0.02 0.02 0.02 2.9e-02 3.9e-03 1.5e-03 2.9e-03
11 NAcc gene expression LOC120096689 0.14 0.05 1.4e-12 0.12 0.12 0.14 0.1 4.2e-14 9.1e-14 6.9e-16 8.3e-12
12 Adipose isoform ratio XR_005493477.1 0.25 0.09 0.0e+00 0.14 0.22 0.22 0.22 1.6e-15 4.2e-24 1.7e-24 3.6e-24
13 NAcc alternative TSS XM_039092874.1 0.04 0.02 1.7e-03 0.01 0.01 0.02 0.01 2.5e-02 6.1e-03 3.7e-03 5.9e-03
14 NAcc isoform ratio XR_005493477.1 0.05 0.03 2.4e-04 0.01 0.04 0.03 0.01 1.1e-02 4.7e-05 3.3e-04 5.2e-02
15 RMTg isoform ratio XR_005493477.1 0.18 0.09 5.0e-03 0.04 0.04 -0.01 0 2.8e-02 2.5e-02 8.1e-01 3.0e-01
16 PL isoform ratio XR_005493477.1 0.09 0.04 7.1e-08 0.04 0.06 0.06 0.05 8.0e-05 2.5e-07 4.7e-07 1.3e-06
17 Brain isoform ratio XR_005493477.1 0.09 0.05 7.0e-07 0.03 0.07 0.06 0.06 6.3e-04 2.4e-07 1.9e-06 2.2e-06
18 BLA gene expression LOC120096689 0.19 0.08 1.6e-05 0.1 0.09 0.09 0.09 6.4e-06 1.0e-05 2.1e-05 1.1e-05
19 Eye gene expression LOC120096689 0.63 0.14 6.3e-04 0.12 0.15 0.05 0.11 6.2e-03 2.7e-03 5.7e-02 1.0e-02
20 NAcc isoform ratio XR_005493474.1 0.09 0.04 3.5e-05 0.04 0.04 0.04 0.05 1.9e-05 1.6e-05 1.8e-05 4.3e-06
21 Liver gene expression LOC120096689 0.08 0.04 6.4e-07 0.02 0.06 0.05 0.04 2.9e-03 5.7e-07 2.1e-06 9.1e-06
22 Liver isoform ratio XR_005493478.1 0.04 0.02 4.1e-04 0.03 0.03 0.03 0.03 1.5e-04 1.4e-04 5.2e-04 3.4e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.10.10.2-0.30.3-0.30.10.2-0.40.2-0.3-0.30.40.4-0.2-0.40.3-0.00.40.40.1-0.10.40.30.4
Area under the delay curve2.02.24.5-1.61.5-1.40.91.4-1.81.0-1.8-1.91.61.6-1.1-1.61.70.52.12.00.9-2.10.40.51.1
BMI with tail0.82.44.7-2.22.2-1.40.91.9-2.01.2-1.7-2.11.41.6-1.4-1.31.51.72.11.90.7-1.21.20.30.4
BMI without tail2.04.07.3-2.32.4-1.70.62.1-2.41.8-2.0-2.32.32.4-2.1-2.22.00.82.02.22.0-0.22.72.01.7
Body weight1.87.512.5-3.53.5-3.22.83.0-3.33.1-3.1-2.93.23.1-3.0-3.12.72.42.62.61.5-1.52.10.51.3
Weight adjusted by age2.02.23.51.6-1.61.8-1.4-1.71.8-1.71.51.7-1.4-1.51.41.4-1.9-0.5-1.6-1.5-1.41.5-1.0-0.8-1.2
Bone surface0.61.13.2-1.41.4-1.31.51.2-1.11.2-0.9-0.90.70.8-0.9-0.70.81.80.80.6-0.4-0.90.4-0.9-0.4
Bone volume0.81.44.0-1.71.7-1.61.61.5-1.31.6-1.1-1.00.81.0-1.1-0.71.02.00.80.60.1-0.70.9-0.6-0.3
Breakpoint value in progressive ratio session2.12.34.6-2.02.1-1.61.62.1-1.71.5-1.5-2.00.91.3-1.3-0.81.62.01.81.51.2-1.60.8-0.2-0.1
Number of licking bursts1.92.33.2-1.71.7-1.61.21.6-1.81.6-1.4-1.61.71.5-1.8-1.61.60.61.51.51.6-0.61.51.01.3
Context. condit. distance diff. score0.20.32.00.5-0.50.5-1.40.10.3-0.7-0.1-0.3-0.6-0.10.90.60.1-0.50.40.30.5-0.7-0.00.6-0.1
Locomotion velocity, session 11.31.45.4-1.61.5-1.52.31.0-1.31.3-0.8-0.91.00.5-1.3-0.90.81.80.90.70.2-1.1-0.5-1.1-0.2
Locomotion distance, session 10.30.42.0-0.40.4-0.41.4-0.3-0.30.50.30.31.1-0.0-1.2-1.1-0.30.2-0.5-0.30.51.1-0.6-0.20.5
Locomotion velocity, session 21.01.23.30.9-1.00.51.0-1.80.7-0.41.21.60.4-1.0-0.4-0.4-1.2-1.2-1.5-1.2-1.01.8-1.3-0.40.6
Locomotion distance, session 21.01.45.40.5-0.50.31.2-1.10.90.11.41.8-0.1-1.1-0.40.2-1.50.6-2.1-1.9-0.52.3-1.0-1.2-0.8
Locomotion velocity, session 30.80.95.4-0.40.4-1.12.3-0.3-0.51.20.30.61.5-0.1-2.1-1.40.1-0.2-0.7-0.30.20.9-0.7-0.31.1
Locomotion distance, session 30.60.63.3-0.10.1-0.71.8-0.4-0.10.90.30.71.1-0.1-1.5-1.1-0.1-0.3-0.8-0.50.10.9-0.6-0.30.8
Stereotopy head waving bouts, day 30.20.30.70.3-0.30.40.2-0.50.4-0.40.70.5-0.4-0.70.10.5-0.70.2-0.4-0.5-0.80.4-0.6-0.7-0.6
Stereotopy head waving duration, day 30.20.30.90.6-0.60.9-0.9-0.60.5-0.90.50.3-0.6-0.50.60.6-0.6-0.5-0.2-0.2-0.30.4-0.20.1-0.2
Locomotion velocity, session 70.10.10.7-0.00.0-0.3-0.40.5-0.10.4-0.2-0.10.00.30.1-0.00.3-0.1-0.1-0.10.80.10.70.60.2
Locomotion distance, session 70.20.31.00.5-0.40.3-0.2-0.30.6-0.10.60.8-0.6-0.50.60.6-0.60.3-0.9-1.0-0.30.6-0.0-0.4-0.7
Stereotopy head waving bouts, day 70.70.83.40.6-0.60.8-1.3-0.70.2-0.60.30.20.60.1-0.2-0.6-0.3-1.8-0.20.11.21.40.51.81.4
Stereotopy head waving duration, day 70.50.61.8-0.60.6-0.40.30.2-0.80.3-0.5-0.61.30.7-1.2-1.30.5-0.60.60.90.90.50.51.11.4
Locomotion velocity, session 80.50.62.2-1.11.1-1.01.40.9-0.70.9-0.3-0.50.40.3-1.0-0.30.31.50.20.10.7-0.10.1-0.5-0.4
Locomotion distance, session 80.10.21.10.2-0.20.10.3-0.30.30.10.40.60.1-0.3-0.4-0.1-0.5-0.0-0.8-0.70.61.1-0.3-0.0-0.0
Degree of sensitization distance1.41.44.70.7-0.71.2-1.7-0.21.1-1.20.80.5-2.1-0.92.22.0-1.00.9-0.5-0.9-0.6-0.2-0.1-0.7-2.1
Degree of sensitization stereotypy1.21.34.4-0.40.5-0.4-0.10.2-0.90.4-0.9-0.81.71.2-1.1-1.70.8-1.40.81.21.50.40.91.92.1
Conditioned locomotion2.32.75.31.6-1.61.5-0.1-2.01.7-1.42.12.1-1.3-2.00.81.3-2.0-0.5-2.0-1.9-2.31.6-1.7-1.4-1.1
Cocaine response after cond. corrected1.21.37.0-1.21.2-1.12.30.8-0.60.9-0.1-0.3-0.1-0.3-0.70.10.12.60.2-0.1-1.1-0.9-0.9-2.2-1.5
Cocaine response after cond. not corrected1.11.35.5-1.61.5-1.42.11.2-1.01.2-0.6-0.80.50.3-1.1-0.40.62.30.70.4-0.4-1.0-0.2-1.4-0.8
Cocaine response before conditioning1.11.33.7-0.60.7-0.6-0.50.8-1.00.6-1.1-1.11.31.4-0.7-1.31.2-0.91.11.31.7-0.41.41.91.7
Saline control response0.91.27.40.9-1.00.70.5-1.30.8-1.10.60.8-0.3-1.00.80.3-0.7-0.4-0.2-0.3-2.1-1.2-2.7-1.6-0.6
Bone: connectivity density0.40.72.31.1-1.11.2-1.4-1.10.7-1.30.50.5-0.4-0.41.00.3-0.6-1.5-0.1-0.0-0.80.4-0.40.60.4
Bone: cortical apparent density1.52.05.22.0-2.01.3-0.6-2.11.5-1.31.51.8-0.5-1.50.80.5-1.2-2.3-1.4-1.2-1.30.7-1.8-0.20.4
Bone: cortical area5.17.711.9-3.33.3-3.52.63.4-3.23.2-3.3-3.12.73.1-2.7-2.73.22.42.92.81.4-2.81.80.31.1
Bone: cortical porosity0.70.71.3-1.01.0-1.11.01.0-1.01.1-0.8-0.80.80.8-1.1-0.80.90.60.70.70.3-0.30.90.20.5
Bone: cortical porosity0.80.91.6-1.21.2-1.31.21.2-1.11.3-0.9-0.90.90.9-1.1-0.81.01.00.80.70.4-0.50.8-0.10.2
Bone: cortical thickness2.74.56.7-2.42.3-2.62.02.2-2.52.3-2.5-2.22.52.4-2.3-2.52.41.02.22.31.0-1.91.10.61.6
Bone: cortical thickness0.70.82.0-1.11.0-1.11.21.0-1.00.9-1.0-0.90.60.7-0.6-0.60.91.11.00.8-0.4-1.4-0.1-0.7-0.1
Bone: cortical tissue density1.82.45.22.1-2.21.5-0.7-2.31.7-1.51.71.9-0.8-1.71.00.7-1.4-2.3-1.6-1.4-1.40.8-2.0-0.30.3
Condit. Reinf. active minus inactive responses0.60.73.51.0-1.01.1-1.9-0.80.5-1.3-0.10.1-0.20.10.90.1-0.3-1.70.10.30.40.2-0.21.10.7
Condit. Reinf. active-inactive response ratio0.40.52.50.8-0.81.1-1.6-0.70.5-1.2-0.10.0-0.3-0.00.90.3-0.4-1.10.20.3-0.10.1-0.20.60.2
Condit. Reinf. active responses0.10.20.80.2-0.20.3-0.90.00.0-0.4-0.5-0.30.20.40.4-0.20.2-0.60.40.50.6-0.4-0.10.60.4
Condit. Reinf. inactive responses0.60.71.4-1.11.1-1.21.01.2-0.91.2-0.8-0.70.70.8-0.7-0.70.81.20.50.40.8-0.80.4-0.2-0.0
Incentive salience index mean0.50.62.2-0.60.5-0.4-0.10.5-0.8-0.0-1.3-1.10.80.9-0.1-0.80.9-0.11.41.40.1-1.5-0.30.30.6
Condit. Reinf. lever presses2.83.87.7-2.42.3-2.32.42.1-2.21.8-2.2-2.11.81.7-1.6-1.82.02.02.32.1-0.0-2.8-0.0-0.80.4
Condit. Reinf. active minus inactive responses0.40.52.7-1.01.0-0.70.51.0-0.70.7-0.4-0.70.30.4-0.7-0.30.41.10.40.41.60.10.60.3-0.0
Condit. Reinf. active-inactive response ratio0.30.32.7-0.20.30.1-0.60.3-0.10.10.2-0.2-0.00.1-0.30.0-0.1-0.0-0.20.01.61.20.91.00.3
Condit. Reinf. active responses0.40.51.5-1.11.1-0.80.80.9-0.90.7-0.6-0.90.70.5-0.8-0.60.60.90.70.71.2-0.40.30.20.2
Condit. Reinf. inactive responses0.50.62.3-0.70.7-0.91.50.5-0.60.6-0.6-0.50.70.3-0.4-0.60.70.90.70.5-0.6-1.5-0.8-1.0-0.1
Condit. Reinf. lever presses0.40.51.6-0.40.4-0.40.20.2-0.70.3-0.7-0.71.20.8-0.6-1.10.7-0.70.81.01.0-0.30.10.91.2
Condit. Reinf. lever reinforcers received0.10.21.4-0.60.6-0.40.30.5-0.50.3-0.2-0.50.30.2-0.4-0.30.30.50.30.41.2-0.00.10.30.1
Conditioned reinforcement - actives0.50.51.6-0.00.1-0.41.00.10.30.70.70.9-0.4-0.5-0.30.3-0.51.1-1.2-1.3-0.40.90.2-1.0-1.0
Conditioned reinforcement - inactives0.30.42.2-0.40.4-1.01.50.4-0.41.1-0.40.00.90.4-0.9-0.90.50.3-0.1-0.1-0.0-0.10.3-0.30.3
Conditioned locomotion0.40.51.50.5-0.50.00.6-0.40.70.30.71.0-0.6-0.80.20.6-0.50.3-1.1-1.2-0.80.4-0.3-1.0-0.8
Patch foraging indifference point 0 sec0.40.61.3-0.90.9-0.70.11.1-0.80.8-0.8-1.00.60.9-0.6-0.60.80.60.70.71.1-0.31.10.70.3
Patch foraging indifference point AUC0.70.83.4-0.30.2-0.51.30.2-0.00.10.1-0.0-0.7-0.60.30.70.11.20.3-0.0-1.4-1.7-1.6-1.9-1.1
Delay disc. indifference point, 0s delay5.35.810.5-2.82.7-2.31.52.5-2.91.9-2.9-3.12.52.7-2.0-2.52.81.13.23.21.6-2.41.71.01.7
Delay disc. indifference point, 16s delay0.10.10.30.3-0.30.3-0.2-0.50.2-0.40.10.20.2-0.10.3-0.2-0.2-0.6-0.10.0-0.1-0.1-0.50.10.3
Delay disc. indifference point, 2s delay3.74.111.1-2.22.2-1.91.62.0-2.31.3-2.6-2.71.72.1-1.2-1.72.41.33.12.80.6-3.30.3-0.20.8
Delay disc. indifference point, 24s delay0.30.30.5-0.40.4-0.3-0.10.6-0.50.3-0.7-0.70.50.7-0.2-0.40.60.10.70.60.6-0.60.40.40.3
Delay disc. indifference point, 4s delay0.70.82.4-0.90.9-0.50.00.8-1.00.2-1.2-1.30.81.0-0.3-0.81.00.31.61.50.3-1.40.20.30.5
Delay disc. indifference point, 8s delay1.61.73.7-1.71.6-1.41.51.3-1.61.0-1.5-1.61.11.2-1.0-1.11.31.11.81.60.4-1.90.0-0.20.4
Indifference point function ln k0.30.41.4-0.60.6-0.50.20.6-0.50.7-0.3-0.40.50.5-0.9-0.50.40.30.10.21.20.61.10.70.4
Indifference point function log k0.30.41.4-0.60.6-0.50.20.6-0.50.7-0.3-0.40.50.5-0.9-0.50.40.30.10.21.20.61.10.70.4
Patch foraging total patch changes 0 sec0.20.41.0-0.70.7-0.5-0.10.9-0.60.6-0.6-0.80.30.7-0.3-0.30.60.70.50.41.0-0.21.00.5-0.0
Patch foraging total patch changes 12 sec0.10.21.2-0.20.3-0.10.40.20.10.20.30.1-0.5-0.30.20.5-0.31.1-0.3-0.5-0.30.20.1-0.6-1.0
Patch foraging total patch changes 18 sec0.30.41.60.4-0.40.5-1.10.10.4-0.70.2-0.2-1.2-0.41.31.2-0.10.10.30.0-0.2-0.9-0.2-0.1-0.7
Patch foraging total patch changes 24 sec0.20.21.1-0.40.4-0.1-0.10.4-0.5-0.1-0.7-0.80.00.50.3-0.10.50.30.90.8-0.2-1.00.10.0-0.0
Patch foraging total patch changes 6 sec0.40.52.9-0.70.7-0.60.50.9-0.50.3-0.6-0.9-0.30.30.20.30.61.30.90.6-0.3-1.7-0.2-0.8-0.8
Patch foraging time to switch 0 sec0.91.46.60.2-0.10.4-1.80.1-0.3-0.1-0.7-0.51.01.2-0.2-1.00.6-1.90.40.81.61.12.02.61.8
Patch foraging water rate 0 sec0.50.72.8-0.90.9-1.01.41.0-0.60.6-0.5-0.8-0.10.2-0.30.10.61.70.70.5-0.3-1.7-0.6-1.2-0.9
Patch foraging water rate 12 sec0.30.42.4-0.20.2-0.10.40.2-0.1-0.2-0.2-0.4-0.4-0.00.60.50.20.80.70.3-1.5-1.6-0.7-1.1-0.8
Patch foraging water rate 18 sec0.60.84.3-0.10.0-0.31.4-0.00.30.20.30.4-0.5-0.50.30.5-0.31.4-0.4-0.7-1.7-0.8-1.1-2.1-1.5
Patch foraging water rate 24 sec0.60.82.90.4-0.40.01.0-0.30.80.10.81.0-0.8-0.90.20.8-0.81.1-1.2-1.4-1.10.2-0.9-1.7-1.5
Patch foraging water rate 6 sec0.71.04.1-1.21.2-1.11.41.2-1.00.8-0.8-1.20.40.6-0.5-0.41.01.51.31.0-0.2-2.0-0.4-0.9-0.4
Seeking ratio, delayed vs. immediate footshock0.20.20.70.4-0.5-0.00.4-0.10.40.00.40.4-0.8-0.60.50.8-0.1-0.0-0.4-0.5-0.0-0.6-0.7-0.5-0.4
Distance traveled before self-admin1.01.13.7-1.41.4-1.31.91.2-1.01.1-0.8-0.90.70.7-0.9-0.70.81.80.80.60.1-1.00.2-0.9-0.5
Distance traveled after self-admin0.10.10.5-0.20.20.00.00.40.0-0.20.0-0.5-0.3-0.1-0.00.30.10.70.40.20.2-0.6-0.0-0.3-0.6
Extensor digitorum longus weight0.72.817.1-1.51.4-1.61.31.6-1.60.9-1.9-2.10.71.2-0.4-0.72.01.12.62.1-1.1-4.1-0.7-0.90.1
Bone: elastic displacement0.91.13.0-1.21.1-1.31.70.7-1.31.2-0.9-0.81.40.8-1.5-1.31.00.30.91.0-0.1-0.60.1-0.01.0
Bone: elastic work3.44.47.9-2.52.5-2.82.62.4-2.42.6-2.3-2.12.22.1-2.4-2.12.31.72.01.90.5-2.01.1-0.21.0
Bone: endosteal estimation2.65.613.0-3.23.2-3.12.73.3-2.53.0-2.4-2.41.62.2-2.3-1.52.33.61.91.60.9-2.11.8-0.9-0.4
Bone: endosteal perimeter1.73.47.2-2.42.4-2.21.52.7-2.02.0-2.2-2.21.11.9-1.4-1.12.02.52.01.70.7-2.11.5-0.4-0.2
Epididymis fat weight2.55.88.8-2.92.9-2.92.72.7-2.83.0-2.5-2.42.82.6-2.8-2.72.51.82.02.02.1-1.12.10.81.4
Delta time in closed arm before/after self-admin0.00.00.00.1-0.00.1-0.2-0.00.1-0.1-0.10.0-0.10.10.20.1-0.10.1-0.1-0.0-0.10.10.10.0-0.1
Delta time in open arm before/after self-admin0.30.30.90.7-0.70.7-1.0-0.40.5-0.90.4-0.0-0.6-0.40.40.6-0.1-0.80.20.2-0.3-0.5-0.30.2-0.0
Diff in mean of infusions in LGA sessions0.91.02.7-1.21.2-0.7-0.21.6-0.90.8-1.0-1.40.41.2-0.5-0.41.01.11.00.91.6-0.51.30.80.0
Delay discount exponential model param2.22.45.01.6-1.61.4-0.9-1.51.8-1.01.92.0-1.6-1.71.11.6-1.8-0.5-2.2-2.1-1.02.2-0.5-0.5-1.1
Extinction: sum of active levers before priming0.20.21.2-0.50.5-0.20.10.7-0.30.1-0.5-0.8-0.10.40.30.20.40.80.70.50.3-1.1-0.1-0.3-0.5
Active lever presses in extinction session 60.40.41.6-0.70.6-0.40.90.4-0.40.1-0.5-0.6-0.10.2-0.00.10.31.30.70.5-0.9-1.0-0.6-1.1-0.8
Bone: final force2.94.79.3-2.42.4-2.92.32.5-2.33.1-2.2-1.82.52.4-2.9-2.52.31.41.41.51.3-0.72.20.71.4
Bone: final moment3.15.010.2-2.62.6-3.12.52.6-2.43.2-2.3-1.82.62.5-3.0-2.62.31.71.41.51.4-0.72.20.51.3
Food consumed during 24 hour testing period2.43.06.6-2.02.0-2.62.52.1-1.82.5-1.7-1.41.61.4-2.2-1.51.91.71.21.11.0-1.60.9-0.30.5
Glucose0.20.40.80.5-0.50.7-0.6-0.30.7-0.50.50.6-0.9-0.50.60.9-0.70.3-0.7-0.8-0.20.7-0.1-0.4-0.9
Heart weight1.01.55.20.6-0.60.6-0.1-0.31.1-0.70.90.9-1.8-1.21.21.7-1.11.4-0.9-1.3-1.4-0.3-1.2-2.0-2.3
Delay discount hyperbolic model param3.03.16.51.9-1.91.7-1.1-1.72.1-1.22.22.3-1.8-1.91.31.8-2.1-0.7-2.5-2.4-1.12.4-0.6-0.5-1.2
Intermittent access intake day 1-15 change1.71.75.0-0.80.7-1.10.60.5-1.31.2-1.6-0.82.21.8-1.1-2.21.4-1.01.01.30.3-0.21.21.32.1
Intermittent access intake escalation2.02.05.0-1.21.2-1.51.00.9-1.61.5-1.7-1.12.21.9-1.5-2.21.6-0.31.11.30.5-0.31.51.11.8
Intermittent access intake escalation 20.90.82.2-0.50.5-0.80.50.4-0.90.9-1.1-0.61.41.3-0.8-1.51.0-0.70.60.90.3-0.11.11.01.5
Intermitt. access day 1 inactive lever presses0.60.71.8-0.60.6-1.11.01.1-0.51.3-0.9-0.70.71.1-0.9-0.71.10.50.30.31.0-0.51.00.10.3
Intermitt. access day 15 inactive lever presses0.70.82.5-0.50.5-0.2-0.60.4-0.60.5-0.8-0.41.21.1-0.4-1.30.4-0.40.10.41.41.11.51.61.1
Intermitt. access escalation Index3.53.15.11.8-1.82.2-1.5-2.11.8-2.21.81.7-2.0-1.92.32.1-2.0-0.8-1.4-1.5-1.71.0-1.8-0.8-1.3
Intermittent access day 1 total infusions4.55.211.51.5-1.51.30.8-1.52.3-1.02.42.6-2.7-2.61.82.7-2.41.6-2.7-3.2-2.91.0-2.2-3.2-3.4
Intermittent access day 15 total infusions0.70.82.90.2-0.3-0.41.6-0.40.50.60.51.2-0.2-0.4-0.00.1-0.60.9-1.3-1.4-1.70.6-0.5-1.6-1.0
Intermittent access terminal intake (last 3 days)0.50.63.10.6-0.60.20.8-0.90.60.00.51.2-0.2-0.30.50.1-0.7-0.0-1.1-1.1-1.80.6-0.6-1.1-0.5
Intermittent access total infusions1.51.74.40.9-0.90.31.0-0.91.3-0.11.21.7-1.1-1.10.91.0-1.20.8-1.8-2.1-2.10.5-1.2-2.0-1.8
Intermittent access day 1 locomotion3.33.57.71.4-1.40.81.1-1.51.9-0.62.32.4-1.9-2.21.11.9-2.00.8-2.4-2.8-2.41.1-1.8-2.5-2.3
Intermittent access day 15 total locomotion0.60.62.00.4-0.4-0.31.4-0.30.60.60.81.1-0.3-0.6-0.10.3-0.50.6-1.3-1.4-1.00.6-0.3-1.2-0.8
Intermittent access total locomotion2.42.76.41.6-1.60.80.6-1.51.8-0.52.02.3-1.5-1.91.01.5-1.70.1-2.4-2.5-2.01.2-1.4-2.0-1.7
Intermittent access standard deviation0.20.20.7-0.30.3-0.40.60.1-0.40.7-0.30.10.60.4-0.4-0.60.30.1-0.1-0.1-0.50.50.80.10.3
Left kidney weight1.95.313.5-2.82.7-3.13.72.0-2.62.9-2.1-1.83.12.0-3.2-2.92.21.81.81.80.6-1.60.4-0.51.3
Right kidney weight2.26.114.8-3.33.3-3.23.82.7-2.83.0-2.4-2.22.32.1-2.7-2.32.23.32.11.70.0-2.20.6-1.50.0
Cocaine induced anxiety1.31.63.11.7-1.71.3-0.9-1.81.5-1.11.31.7-0.4-1.00.70.4-1.3-1.8-1.6-1.3-0.71.8-0.40.20.2
Post-drug Anxiety0.70.84.11.0-0.90.8-0.8-1.10.5-0.80.50.60.6-0.2-0.2-0.5-0.5-2.0-0.6-0.10.81.4-0.11.31.4
Baseline Anxiety1.92.08.5-1.31.3-1.0-0.21.4-1.40.9-1.2-1.71.31.2-1.7-1.21.4-0.21.51.72.9-0.31.32.01.7
Tail length2.06.011.1-2.92.9-3.12.52.8-2.83.3-2.4-2.22.82.7-2.8-2.82.61.61.71.72.2-0.82.61.11.6
Length with tail2.28.013.7-3.23.2-3.63.22.9-3.23.7-3.0-2.43.63.2-3.4-3.63.01.52.02.22.3-1.02.31.12.2
Length without tail0.61.35.3-1.31.2-1.52.30.9-1.11.4-1.1-0.71.40.9-1.4-1.30.91.30.60.60.1-0.9-0.4-0.90.2
Times rat made contact with spout3.03.55.0-1.91.9-2.21.91.9-2.22.1-2.1-1.92.22.0-2.1-2.22.20.51.91.91.5-1.61.10.81.7
Lifetime Intake0.80.93.20.2-0.3-0.31.6-0.30.60.50.61.1-0.5-0.60.30.5-0.61.1-1.2-1.5-1.70.3-0.7-1.8-1.4
Liver weight, left0.40.63.50.8-0.80.8-0.4-1.30.2-1.0-0.00.20.80.10.3-0.8-0.2-1.90.20.4-0.7-0.0-1.10.51.2
Liver weight, right0.61.04.1-0.90.8-0.81.20.5-1.00.4-1.3-1.11.20.9-0.5-1.11.00.31.51.3-0.6-2.0-0.9-0.60.5
Locomotor activity0.20.31.2-0.10.1-0.31.0-0.10.10.30.50.3-0.1-0.6-0.40.2-0.20.7-0.3-0.4-0.6-0.2-0.9-1.1-0.5
Locomotor testing distance0.60.93.30.1-0.10.30.5-0.10.7-0.21.10.7-1.2-1.30.41.2-1.01.6-1.0-1.2-0.70.4-0.9-1.6-1.8
Locomotor testing rearing0.81.22.4-1.31.3-1.30.91.5-1.21.2-1.2-1.40.71.0-0.9-0.71.31.21.21.10.3-1.40.9-0.10.1
Locomotion in novel chamber3.34.17.71.7-1.82.1-0.9-2.32.0-2.32.22.0-2.3-2.61.72.2-2.50.1-1.7-1.8-2.50.8-2.8-2.1-2.1
Locomotion in novel chamber post-restriction0.30.41.6-0.80.7-0.61.20.4-0.60.4-0.4-0.50.40.1-0.7-0.30.30.90.60.6-0.1-0.9-0.7-0.9-0.1
Fecal boli incidents, locomotor time 10.40.42.3-0.60.6-0.60.30.9-0.50.5-0.7-1.00.20.5-0.2-0.10.90.61.00.80.1-1.50.2-0.2-0.1
Change in fecal boli incidents, locomotor task2.72.56.1-2.12.1-2.22.51.9-1.82.4-1.2-1.01.51.2-2.1-1.51.22.00.60.51.5-0.11.3-0.00.3
Time >=10cm from walls, locomotor time 10.00.00.1-0.00.00.0-0.1-0.1-0.1-0.0-0.1-0.10.10.0-0.3-0.10.1-0.10.10.2-0.20.00.10.00.2
Bouts of movement, locomotor time 10.60.62.0-0.70.8-0.8-0.11.1-0.70.9-0.7-0.80.60.8-0.9-0.60.80.30.50.71.20.11.40.90.6
Total resting periods, locomotor time 11.01.13.0-0.91.0-1.0-0.11.4-0.91.2-1.0-1.10.81.1-1.1-0.81.20.40.70.81.5-0.11.71.20.7
Rest time, locomotor task time 11.51.63.6-1.61.6-1.50.71.9-1.41.6-1.4-1.40.91.3-1.5-0.91.41.31.01.01.3-0.51.70.50.3
Distance moved, locomotor task time 13.33.67.62.3-2.32.4-1.5-2.82.1-2.41.92.2-1.3-1.72.11.2-2.2-1.8-1.8-1.6-1.81.4-2.1-0.5-0.6
Vertical activity count, locomotor time 12.72.85.12.0-2.02.1-1.0-2.31.9-2.21.61.7-1.4-1.62.01.3-1.9-1.1-1.4-1.4-2.00.7-2.1-1.1-1.1
Time >=10cm from walls, locomotor time 21.11.22.01.1-1.11.2-0.5-1.41.2-1.11.21.4-0.8-1.10.70.8-1.4-0.3-1.4-1.3-1.01.4-0.9-0.7-0.8
Bouts of movement, locomotor time 20.30.32.60.1-0.1-0.20.4-0.20.20.50.40.80.2-0.1-0.7-0.2-0.40.1-1.0-0.8-0.31.60.6-0.20.0
Total resting periods, locomotor time 20.40.43.0-0.10.1-0.40.30.1-0.10.80.10.50.60.3-1.0-0.6-0.1-0.1-0.8-0.50.21.71.20.40.5
Rest time, locomotor task time 22.83.26.0-2.12.1-1.90.82.5-2.02.1-2.0-2.01.52.0-1.8-1.42.01.21.71.62.0-0.72.41.41.0
Distance moved, locomotor task time 22.52.95.82.0-2.01.9-0.9-2.41.9-1.81.92.2-1.3-1.81.51.3-2.0-1.4-1.9-1.8-1.51.5-1.9-0.8-0.7
Vertical activity count, locomotor time 22.93.14.71.7-1.81.9-0.6-2.21.9-1.91.92.0-1.8-2.01.61.7-2.1-0.3-1.7-1.8-2.11.2-2.2-1.6-1.5
Light reinforcement 10.20.41.20.0-0.00.6-0.4-0.30.3-0.80.20.0-0.7-0.51.00.7-0.60.80.1-0.1-0.9-0.3-0.7-0.8-1.1
Light reinforcement 20.20.30.9-0.10.00.1-0.6-0.0-0.4-0.3-0.7-0.60.60.50.3-0.60.5-0.80.90.90.1-0.90.00.70.8
Bone: marrow area2.55.512.3-3.13.1-3.12.73.3-2.53.0-2.4-2.31.62.2-2.2-1.62.33.51.91.60.9-2.01.7-0.8-0.4
Bone: maximum diameter3.66.613.8-3.43.4-3.32.83.5-2.83.1-2.8-2.71.72.5-2.3-1.72.63.72.42.00.9-2.41.8-0.7-0.3
Bone: maximum force2.33.97.0-2.42.4-2.62.12.4-2.22.7-2.1-1.82.02.2-2.4-2.02.01.91.51.51.0-0.91.90.30.8
Bone: maximum moment2.54.47.9-2.62.6-2.82.32.6-2.32.8-2.2-1.92.12.2-2.6-2.12.12.11.51.51.1-0.91.90.20.7
Mean time between licks in bursts0.50.83.1-0.30.2-0.50.20.1-0.70.4-0.8-0.61.40.9-0.9-1.30.9-1.30.81.10.7-0.30.31.11.8
Mean num. licks in bursts0.40.51.00.9-0.90.6-0.1-0.90.8-0.60.60.9-0.5-0.70.70.5-0.7-0.4-0.8-0.9-0.90.2-1.0-0.7-0.5
Cd content in liver2.02.211.21.7-1.71.9-3.3-1.01.3-1.70.60.6-0.9-0.21.90.9-0.8-2.3-0.7-0.41.51.30.82.20.5
Co content in liver0.20.31.60.6-0.50.2-0.1-0.50.50.10.40.90.1-0.10.0-0.1-0.5-0.5-1.1-0.90.01.30.30.20.1
Cu content in liver0.50.62.1-0.60.6-0.70.80.2-0.90.7-0.9-0.61.41.0-0.9-1.40.8-0.40.70.90.0-0.10.30.51.2
Fe content in liver0.30.41.40.4-0.40.50.4-0.80.5-0.40.80.90.0-0.60.1-0.1-0.90.1-1.0-0.9-0.51.2-0.7-0.6-0.4
K content in liver1.91.98.1-1.41.3-1.62.80.7-1.41.2-1.0-0.81.50.6-1.5-1.41.01.21.21.1-1.7-1.7-1.1-1.50.3
Mg content in liver0.90.95.5-1.11.1-1.12.40.4-0.81.2-0.2-0.10.90.1-1.4-0.80.31.40.10.0-1.00.0-0.4-1.2-0.2
Mn content in liver3.13.69.9-2.12.1-2.53.21.5-2.12.5-1.8-1.22.81.8-2.7-2.81.71.21.11.20.4-0.80.5-0.21.2
Na content in liver0.50.63.7-0.70.6-1.01.90.3-0.60.9-0.2-0.10.70.1-1.0-0.60.30.80.20.1-1.0-0.5-0.7-1.1-0.1
Rb content in liver1.31.63.41.8-1.81.6-1.3-1.81.4-1.50.71.3-0.5-0.61.40.5-1.1-1.8-0.9-0.8-1.80.6-1.1-0.1-0.0
Se content in liver3.03.610.2-2.52.4-2.53.21.8-2.22.5-1.7-1.52.41.7-2.7-2.31.61.91.31.30.5-0.60.7-0.50.8
Sr content in liver0.10.10.40.2-0.20.00.1-0.00.3-0.00.20.4-0.3-0.20.20.3-0.30.4-0.4-0.5-0.5-0.1-0.3-0.5-0.6
Zn content in liver0.40.41.2-0.50.5-0.70.50.5-0.61.0-0.5-0.20.90.7-1.1-0.90.5-0.10.00.20.40.61.10.60.8
Bone: minimum diameter4.48.116.1-3.63.6-3.41.94.0-3.23.2-3.3-3.42.13.2-2.4-2.13.13.12.92.72.0-2.52.80.50.5
Time in familiar zone, hab. session 10.70.62.8-0.00.00.20.7-0.20.3-0.50.40.3-0.7-0.70.60.7-0.61.2-0.1-0.4-1.5-0.7-1.3-1.7-1.4
Time in novel zone, hab. session 10.40.41.90.6-0.60.6-1.4-0.20.6-0.30.40.4-0.6-0.30.50.7-0.3-0.7-0.6-0.50.81.00.90.90.1
Total zone transitions, hab. session 10.71.05.6-1.21.2-1.22.40.5-0.81.4-0.20.11.20.3-1.7-1.10.11.4-0.3-0.30.30.7-0.1-0.9-0.0
Total locomotion distance, hab. session 10.70.93.0-1.31.3-1.21.70.7-1.01.3-0.5-0.41.30.7-1.6-1.20.41.10.10.10.90.80.5-0.00.4
Locomotion velocity, hab. session 11.21.74.2-1.71.7-1.52.11.0-1.51.6-1.0-0.81.91.1-2.0-1.80.81.10.50.71.20.30.60.20.8
Time in familiar zone, hab. session 22.72.85.72.1-2.22.0-1.2-2.41.8-2.21.61.7-1.1-1.71.71.1-1.7-1.8-1.3-1.2-1.80.6-2.2-0.7-0.4
Time in novel zone, hab. session 21.91.94.8-1.81.8-1.70.72.1-1.41.9-1.1-1.30.71.2-1.4-0.61.21.70.70.72.2-0.12.00.80.1
Total zone transitions, hab. session 20.40.52.5-0.20.2-0.61.6-0.3-0.20.80.10.61.10.0-1.2-1.0-0.10.0-0.7-0.50.11.0-0.4-0.30.5
Total locomotion distance, hab. session 20.40.52.3-0.20.2-0.30.6-0.1-0.20.7-0.00.41.10.5-1.0-1.1-0.0-0.4-0.7-0.41.11.50.60.70.9
Locomotion velocity, hab. session 20.30.41.9-0.20.2-0.40.9-0.1-0.20.80.00.51.00.3-1.0-1.0-0.1-0.0-0.8-0.50.81.40.40.30.5
Novel to familiar place preference ratio0.30.31.50.1-0.10.1-1.20.50.0-0.1-0.4-0.4-0.30.30.70.30.4-0.30.30.30.9-0.50.81.00.1
Novelty place preference0.20.21.40.2-0.20.2-1.20.40.1-0.1-0.3-0.3-0.40.20.70.40.3-0.30.20.20.8-0.40.70.80.0
Time in novel zone, NPP test0.30.31.80.2-0.20.2-1.40.40.1-0.2-0.3-0.4-0.40.20.80.40.3-0.40.30.20.8-0.40.80.90.1
Total zone transitions, NPP test2.23.17.4-1.91.9-1.92.11.3-1.92.1-1.6-1.22.71.9-2.6-2.71.40.60.91.21.90.41.21.01.7
Total locomotion distance, NPP test1.21.75.7-0.91.0-0.90.50.7-1.01.3-0.8-0.51.91.4-1.7-1.90.7-0.40.10.52.41.61.71.81.7
Locomotion velocity, NPP test1.01.44.6-1.01.0-1.00.90.7-0.91.4-0.7-0.31.81.2-1.8-1.80.60.1-0.20.22.11.51.51.31.2
Intraocular pressure0.30.52.30.2-0.20.2-1.0-0.0-0.0-0.20.1-0.30.30.1-0.4-0.20.3-1.30.30.61.30.40.71.51.2
Delta distance traveled before/after self-admin0.50.53.30.6-0.50.8-1.8-0.10.4-0.70.2-0.2-0.4-0.10.30.4-0.0-1.10.10.20.90.50.71.40.5
Delta ambulatory time before/after self-admin0.70.83.51.0-0.91.2-1.9-0.51.0-1.00.80.5-1.3-0.71.01.2-0.8-0.5-0.7-0.7-0.10.80.20.4-0.6
Parametrial fat weight0.10.31.5-0.20.2-0.40.60.0-0.10.70.30.40.60.0-1.1-0.5-0.10.0-0.6-0.50.61.20.50.30.4
Pavlov. Cond. lever latency2.93.67.21.8-1.71.7-1.0-1.62.1-1.32.72.3-2.4-2.41.52.4-2.3-0.0-2.6-2.7-0.62.3-0.7-0.8-1.8
Pavlov. Cond. magazine entry latency1.62.13.6-1.91.9-1.71.31.8-1.71.7-1.7-1.61.31.6-1.3-1.31.51.71.41.30.8-0.91.30.10.3
Pavlov. Cond. change in total contacts4.54.98.0-2.02.0-1.90.62.0-2.41.7-2.8-2.52.72.8-2.1-2.72.6-0.32.62.82.0-1.41.92.02.5
Pavlov. Cond. index score3.03.86.6-2.32.2-2.11.62.1-2.31.8-2.6-2.32.22.3-1.8-2.22.21.22.42.40.7-1.91.20.41.2
Pavlov. Cond. latency score3.54.47.7-2.32.3-2.21.52.1-2.51.9-2.8-2.52.42.5-1.9-2.42.41.02.62.60.9-2.01.20.71.5
Pavlov. Cond. lever contacts2.93.46.5-1.81.8-1.81.11.8-2.11.5-2.6-2.22.22.3-1.5-2.22.20.42.32.40.8-2.01.00.71.5
Pavlov. Cond. magazine entry number1.92.33.71.9-1.91.8-1.3-1.91.7-1.91.81.6-1.5-1.71.51.5-1.7-1.4-1.4-1.4-1.00.9-1.5-0.3-0.6
Pavlov. Cond. intertrial magazine entries1.21.43.11.3-1.31.5-1.3-1.21.3-1.81.10.9-1.4-1.31.81.4-1.3-0.5-0.7-0.7-0.6-0.1-1.7-0.6-1.0
Pavlov. Cond. lever-magazine prob. diff.3.34.27.2-2.32.3-2.21.62.1-2.41.8-2.7-2.42.32.4-1.8-2.32.41.02.62.60.6-2.11.10.41.4
Pavlov. Cond. response bias2.73.35.6-2.12.1-2.01.32.1-2.11.8-2.4-2.11.92.2-1.6-1.92.11.22.12.11.0-1.71.30.41.0
Pavlov. Cond. lever latency0.20.31.4-0.60.6-0.20.20.6-0.40.1-0.6-0.5-0.40.20.30.30.31.20.70.4-1.1-0.80.3-0.8-0.8
Pavlov. Cond. magazine entry latency1.21.45.61.7-1.71.2-1.5-1.41.3-1.01.21.3-0.5-0.80.80.6-0.8-2.4-1.2-0.90.31.1-0.31.00.8
Pavlov. Cond. change in total contacts0.70.91.71.2-1.21.0-0.7-1.21.1-0.91.31.1-0.7-1.20.50.8-1.1-1.0-1.2-1.00.51.1-1.00.1-0.0
Pavlov. Cond. index score0.81.04.11.3-1.30.8-0.8-1.31.0-0.61.11.10.0-0.60.10.0-0.7-2.0-1.2-0.80.71.4-0.40.91.0
Pavlov. Cond. latency score0.70.93.61.3-1.30.8-0.6-1.30.9-0.61.11.1-0.0-0.70.00.0-0.7-1.9-1.2-0.80.61.4-0.40.80.9
Pavlov. Cond. lever contacts0.10.20.80.5-0.50.2-0.1-0.50.4-0.20.50.50.2-0.3-0.1-0.2-0.3-0.8-0.6-0.40.90.5-0.40.40.5
Pavlov. Cond. magazine entry number1.31.65.2-1.81.8-1.41.51.6-1.41.2-1.3-1.30.81.1-0.8-0.81.02.31.30.9-0.4-1.30.6-0.9-0.6
Pavlov. Cond. intertrial magazine entries0.50.74.4-1.11.2-0.71.20.8-0.70.6-0.5-0.60.00.3-0.4-0.00.22.10.50.2-0.8-0.40.1-1.2-1.1
Pavlov. Cond. lever-magazine prob. diff.0.81.04.11.3-1.30.8-0.6-1.41.0-0.61.11.20.1-0.70.1-0.1-0.7-2.0-1.2-0.80.51.4-0.60.81.0
Pavlov. Cond. response bias0.60.82.41.3-1.30.8-0.7-1.11.0-0.71.11.0-0.3-0.80.40.3-0.7-1.6-1.1-0.80.70.8-0.80.50.5
Time in closed arm before self-admin0.20.20.8-0.30.3-0.50.6-0.1-0.50.5-0.30.10.90.4-0.6-0.90.2-0.20.00.1-0.30.20.20.10.6
Time in closed arm after self-admin0.30.31.4-0.10.20.0-0.6-0.0-0.30.2-0.4-0.10.50.7-0.1-0.60.1-0.60.00.20.80.80.91.20.8
Time in open arm before self-admin0.70.82.70.4-0.40.7-0.4-0.30.8-0.70.50.6-1.3-0.91.21.3-0.91.0-0.8-0.9-1.00.2-0.8-1.1-1.7
Time in open arm after self-admin1.61.73.21.4-1.41.6-1.4-1.21.5-1.81.30.9-1.7-1.61.61.7-1.3-0.4-0.7-0.8-1.4-0.1-1.3-0.9-1.3
Bone: periosteal estimation5.110.619.1-4.24.2-4.23.44.4-3.64.1-3.6-3.42.63.3-3.2-2.63.44.02.92.61.6-2.92.4-0.40.3
Bone: periosteal perimeter3.76.211.1-3.23.2-3.02.33.3-2.82.9-2.8-2.82.02.6-2.4-2.02.62.92.52.31.4-2.21.9-0.00.4
Bone: post-yield work0.40.52.8-0.30.40.5-0.50.40.2-0.40.2-0.2-1.1-0.30.81.1-0.51.7-0.1-0.3-0.10.20.3-0.7-1.6
Progressive ratio test 1 active lever presses4.44.610.81.4-1.51.40.2-1.72.0-1.42.12.2-2.5-2.42.22.4-2.31.4-2.1-2.5-3.30.5-2.5-3.1-3.1
Progressive ratio test 1 breakpoint4.44.610.91.5-1.51.40.3-1.72.0-1.42.22.3-2.4-2.42.22.3-2.31.2-2.2-2.6-3.30.6-2.5-3.1-3.0
Progressive ratio test 1 inactive lever presses0.20.20.60.1-0.1-0.10.40.00.30.30.20.3-0.5-0.20.60.4-0.10.6-0.4-0.7-0.7-0.20.0-0.8-0.8
Progressive ratio test 2 active lever presses1.71.84.20.9-1.00.40.9-1.01.3-0.21.41.8-1.2-1.30.71.1-1.30.8-1.9-2.0-2.00.9-1.3-2.0-1.7
Progressive ratio test 2 breakpoint1.51.74.50.9-1.00.50.8-1.11.3-0.31.31.8-1.1-1.20.91.0-1.30.7-1.8-2.0-2.10.8-1.3-2.0-1.7
Progressive ratio test 2 inactive lever presses0.60.72.00.5-0.5-0.00.7-0.30.80.20.91.0-0.9-0.80.40.8-0.60.8-1.2-1.3-1.00.2-0.7-1.4-1.2
Incentive Sensitization - Responses0.70.71.80.9-1.00.7-0.0-0.91.0-0.60.81.1-0.8-0.71.00.7-0.8-0.2-0.9-1.0-1.40.1-1.0-1.0-0.8
Incentive Sensitization - Breakpoint0.70.71.61.0-1.00.7-0.2-1.01.0-0.60.71.1-0.8-0.71.00.7-0.8-0.3-1.0-1.1-1.30.2-0.9-0.9-0.7
Sum of active levers in priming session hrs 5-60.60.62.2-0.00.0-0.31.00.30.50.40.70.4-0.9-0.8-0.30.9-0.41.5-0.7-0.9-0.2-0.1-0.5-1.5-1.5
Progressive ratio0.20.20.80.1-0.10.30.2-0.10.5-0.20.50.4-0.7-0.60.00.7-0.50.7-0.5-0.60.00.2-0.5-0.8-0.9
Food seeking constrained by brief footshock0.81.02.40.6-0.70.50.2-0.51.0-0.51.00.9-1.2-1.20.91.2-0.90.8-1.0-1.2-1.0-0.2-1.4-1.5-1.5
Seeking ratio, punishment vs. effort0.10.20.80.3-0.30.10.2-0.30.3-0.10.40.4-0.3-0.40.50.3-0.30.1-0.4-0.5-0.9-0.2-0.6-0.6-0.4
Retroperitoneal fat weight0.20.71.7-1.11.1-1.21.31.1-0.81.3-0.6-0.50.80.7-1.1-0.80.71.30.30.20.9-0.10.8-0.2-0.0
Reaction time number correct0.30.42.50.5-0.60.10.7-0.40.6-0.30.50.4-0.4-0.70.30.4-0.30.1-0.2-0.3-0.9-1.1-1.6-1.2-0.6
Reaction time mean minus median0.10.10.60.3-0.30.1-0.7-0.10.1-0.3-0.1-0.1-0.0-0.00.20.00.2-0.80.30.40.3-0.7-0.40.50.5
Reaction time mean minus median AUC0.50.62.41.2-1.20.8-1.1-1.00.9-0.70.80.9-0.3-0.70.20.3-0.6-1.5-0.8-0.60.20.8-0.50.60.5
Reaction time num false alarms1.42.04.7-1.71.7-1.20.71.4-1.80.7-1.5-2.01.31.2-1.0-1.31.50.82.22.01.1-1.90.30.60.8
Reaction time num false alarms AUC0.91.23.1-1.41.3-0.90.51.1-1.40.5-1.1-1.61.00.9-0.7-1.01.20.51.81.61.1-1.50.30.60.7
Reaction time trials correct on left0.30.42.50.5-0.60.10.7-0.40.6-0.30.50.4-0.4-0.70.30.4-0.30.1-0.2-0.3-0.9-1.1-1.6-1.2-0.6
Reaction time trials on left0.30.52.70.6-0.60.10.7-0.40.6-0.30.60.4-0.5-0.70.30.5-0.30.1-0.3-0.4-0.9-1.1-1.6-1.3-0.6
Reaction time mean0.60.92.90.7-0.70.9-1.0-0.31.0-0.80.90.5-1.7-1.11.01.7-0.80.5-0.5-0.8-0.8-0.0-0.4-0.8-1.4
Reaction time mean AUC0.91.23.60.9-0.91.0-0.9-0.51.2-1.01.20.8-1.9-1.41.11.9-1.10.5-0.9-1.1-1.00.2-0.7-1.0-1.7
Median of all reaction times0.91.23.70.6-0.61.0-0.8-0.41.1-0.91.10.7-1.9-1.31.11.9-1.00.9-0.8-1.1-1.10.3-0.4-1.1-1.8
Reaction time omissions0.10.21.00.2-0.20.00.4-0.10.3-0.20.50.1-0.5-0.6-0.10.6-0.20.2-0.2-0.20.3-0.5-1.0-0.6-0.4
Reaction time false alarm rate1.41.93.4-1.81.8-1.20.51.4-1.81.0-1.5-1.81.41.3-1.2-1.41.40.71.81.81.4-0.91.21.01.0
Reaction time premature initiation rate0.50.73.90.4-0.40.2-0.9-0.3-0.1-0.2-0.4-0.20.90.6-0.1-0.90.5-2.00.30.61.10.20.61.81.7
Reaction time premature initiations0.20.32.00.7-0.70.3-0.4-0.60.4-0.40.20.30.3-0.10.2-0.30.0-1.4-0.10.10.4-0.2-0.50.60.8
Std. dev. reaction times0.60.82.31.0-1.01.0-1.5-0.61.0-1.10.80.5-1.3-1.01.21.3-0.6-0.6-0.3-0.4-0.4-0.4-0.8-0.1-0.6
Reaction time trials completed0.30.52.70.6-0.60.10.7-0.40.6-0.30.60.4-0.5-0.70.30.5-0.30.1-0.3-0.4-0.9-1.1-1.6-1.3-0.6
Reaction time trials AUC0.40.52.90.5-0.50.10.7-0.40.5-0.40.50.3-0.5-0.70.40.5-0.30.2-0.1-0.3-1.0-1.2-1.7-1.4-0.7
Run reversals in cocaine runway, females2.52.45.42.0-2.01.4-0.8-1.91.8-1.61.81.7-1.3-2.01.01.4-1.5-1.2-1.3-1.3-1.7-0.0-2.3-1.4-0.8
Run reversals in cocaine runway, males1.01.02.91.1-1.10.9-0.1-1.51.0-0.71.11.5-0.2-0.90.30.2-1.2-1.0-1.4-1.2-0.71.7-0.8-0.30.0
Latency to leave start box in cocaine runway2.52.79.4-0.60.7-0.5-1.30.9-1.30.5-1.5-1.61.71.7-1.0-1.71.6-1.91.62.02.3-0.12.13.12.7
Latency to leave start box in cocaine runway, F3.13.48.4-1.11.1-1.1-0.21.2-1.80.9-2.0-2.12.32.0-1.4-2.32.1-1.52.22.62.0-1.11.62.62.9
Latency to leave start box in cocaine runway, M0.50.52.30.2-0.10.3-1.20.10.10.2-0.00.10.20.4-0.2-0.20.1-0.8-0.3-0.11.01.41.51.50.7
Std. dev. time between licks in bursts3.44.17.4-2.22.2-2.72.52.1-2.22.7-1.8-1.62.41.9-2.7-2.42.10.81.31.52.5-1.01.20.91.8
Total sessions with >9 infusions1.41.56.2-0.30.3-0.62.30.00.40.80.71.0-0.8-0.8-0.00.8-0.72.2-1.2-1.6-1.60.3-0.8-2.5-2.0
Short access day 1 total inactive lever presses1.31.54.1-1.41.4-1.82.01.4-1.12.0-0.9-0.71.31.2-1.5-1.21.11.30.30.20.8-0.21.4-0.10.2
Short access day 10 total inactive lever presses0.30.31.80.5-0.50.3-1.00.40.3-0.3-0.3-0.5-0.40.30.80.40.6-0.50.50.30.4-1.40.10.3-0.1
Short access day 1 total infusions1.21.35.4-1.31.3-1.72.31.1-1.21.8-1.0-0.71.01.0-1.2-1.11.11.20.60.3-0.3-0.80.7-0.60.1
Short access day 10 total infusions1.92.16.31.3-1.40.90.5-1.41.5-0.71.41.8-1.4-1.41.51.3-1.40.1-1.7-2.0-2.50.5-1.4-1.8-1.6
Short access total infusions0.30.31.7-0.00.0-0.51.30.00.10.60.10.4-0.1-0.10.20.10.00.6-0.4-0.7-1.0-0.3-0.2-1.0-0.6
Short access day 1 locomotion0.50.52.0-0.90.9-1.11.40.8-0.61.4-0.2-0.10.20.3-0.7-0.20.41.2-0.2-0.40.10.20.9-0.3-0.3
Short access day 10 total locomotion1.01.14.9-0.10.0-0.72.1-0.10.40.80.91.0-0.6-1.0-0.60.7-0.61.5-1.1-1.4-1.50.3-0.7-2.2-1.4
Short access total locomotion1.21.33.80.7-0.7-0.01.4-0.81.00.21.31.5-1.0-1.30.21.0-0.90.6-1.5-1.8-1.70.3-1.2-2.0-1.3
One hour access (0.3 mA shock)0.91.05.1-0.80.8-1.02.30.3-0.31.3-0.10.70.20.2-0.7-0.3-0.42.0-1.0-1.1-1.11.00.2-1.6-1.1
Compulsive drug intake0.30.31.20.3-0.30.4-1.0-0.4-0.1-0.5-0.3-0.00.30.50.2-0.3-0.1-1.10.20.40.40.40.31.10.9
One hour access (shock baseline)0.80.94.7-0.50.5-0.82.20.20.01.10.10.70.1-0.0-0.6-0.2-0.31.8-1.0-1.2-1.10.6-0.1-1.7-1.2
Social response proportion0.40.50.90.9-0.90.5-0.7-0.40.9-0.40.90.9-0.7-0.70.60.7-0.7-0.4-1.0-1.00.20.6-0.2-0.0-0.4
Social responses0.20.31.9-0.70.7-0.61.10.6-0.30.7-0.1-0.20.10.2-0.4-0.10.11.4-0.0-0.20.1-0.10.2-0.8-0.7
Social time0.20.32.40.4-0.40.4-1.50.20.2-0.4-0.0-0.4-0.50.20.80.50.3-0.70.40.30.5-0.30.91.00.1
Soleus weight0.92.610.3-1.61.5-1.91.61.7-1.71.4-2.0-1.81.21.4-0.9-1.31.91.22.11.8-0.4-3.2-0.3-0.60.3
Bone: stiffness1.22.03.4-1.41.4-1.50.81.4-1.51.5-1.7-1.31.81.8-1.7-1.81.50.21.21.40.9-0.31.61.11.4
Tibialis anterior weight0.62.112.7-1.31.2-0.9-0.11.6-1.40.2-1.8-2.20.21.20.4-0.21.71.02.72.2-0.5-3.60.0-0.1-0.1
Time to tail flick, vehicle, before self-admin0.60.62.3-0.30.3-0.2-0.80.6-0.60.2-0.9-0.90.60.9-0.1-0.50.8-0.80.91.01.5-0.40.81.41.1
Time to tail flick, vehicle, after self-admin2.42.65.5-1.21.2-0.9-0.81.7-1.50.7-1.9-2.31.21.8-0.6-1.12.0-0.52.32.42.2-1.61.62.11.6
Time to tail flick, test, before self-admin0.30.31.70.3-0.40.2-1.0-0.3-0.2-0.3-0.6-0.20.50.50.4-0.60.3-1.30.30.60.1-0.10.11.01.1
Time to tail flick, test, after self-admin1.01.13.0-0.30.2-0.1-0.90.4-0.7-0.1-1.2-1.40.81.00.0-0.71.3-1.31.71.71.0-1.40.41.51.5
Delta time to tail flick, vehicle, before/after SA1.01.04.4-1.00.9-0.90.61.1-1.00.5-1.0-1.50.60.8-0.3-0.51.30.61.61.50.2-2.10.1-0.10.3
Delta time to tail flick, test, before/after SA0.20.21.7-0.10.10.0-0.10.3-0.1-0.2-0.1-0.7-0.3-0.10.30.40.40.10.80.50.2-1.3-0.2-0.1-0.2
Tibia length6.117.227.0-5.15.1-5.24.44.8-4.85.2-4.6-4.04.74.6-4.9-4.74.33.43.53.52.4-2.23.30.72.1
Ambulatory time before self-admin1.71.74.1-1.71.6-1.72.01.5-1.51.5-1.4-1.31.21.2-1.2-1.21.31.51.31.10.5-1.50.4-0.40.2
Ambulatory time after self-admin0.30.31.8-0.70.7-0.30.30.8-0.30.2-0.4-0.7-0.40.1-0.10.40.31.30.60.40.2-1.00.0-0.6-0.9
Bone: tissue strength1.81.83.1-1.71.7-1.61.21.7-1.51.7-1.2-1.21.31.4-1.6-1.31.21.40.80.91.5-0.11.60.50.5
Total heroin consumption1.51.88.1-1.91.9-1.51.82.1-1.11.6-1.0-1.40.31.0-1.0-0.21.02.80.90.50.7-0.81.1-0.9-1.1
Bone: trabecular number0.10.21.00.2-0.20.4-0.9-0.3-0.0-0.40.0-0.10.10.20.2-0.1-0.0-0.90.20.30.10.60.71.00.6
Bone: trabecular spacing0.10.10.40.2-0.20.1-0.2-0.00.3-0.20.10.1-0.4-0.30.40.5-0.10.1-0.1-0.20.4-0.5-0.6-0.3-0.4
Bone: trabecular thickness0.20.21.10.2-0.20.30.1-0.40.3-0.50.20.2-0.3-0.40.50.3-0.40.2-0.0-0.1-1.1-0.4-0.8-0.7-0.5
Bone: trabecular tissue density0.30.42.10.0-0.00.0-0.80.2-0.3-0.0-0.3-0.50.40.4-0.2-0.30.5-1.10.50.71.4-0.10.61.41.1
Water consumed over 24 hours2.63.16.2-1.91.8-2.42.02.1-1.92.5-1.8-1.51.91.8-2.2-1.92.00.91.21.21.9-1.21.30.61.2
Number of responses in last shaping day3.13.35.6-2.12.1-2.11.61.9-2.02.4-1.7-1.42.32.1-2.3-2.31.71.01.11.21.60.22.31.11.4