Hub : Genes

LOC120096233

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression LOC120096233 0.15 0.06 5.6e-17 0.09 0.08 0.08 0.08 2.9e-13 8.4e-12 4.3e-12 2.5e-12
2 PL gene expression LOC120096233 0.11 0.05 3.6e-11 0.08 0.08 0.07 0.08 4.4e-09 9.3e-09 3.8e-08 7.7e-09
3 Brain intron excision ratio chr13_34804337_34840383 0.05 0.03 7.3e-04 0.03 0.03 0.03 0.03 2.1e-03 5.8e-04 1.1e-03 8.9e-04
4 IC gene expression LOC120096233 0.21 0.09 1.2e-05 0.08 0.06 0.05 0.07 2.3e-04 1.3e-03 4.7e-03 5.5e-04
5 OFC gene expression LOC120096233 0.21 0.12 1.2e-03 0.06 0.1 0.04 0.09 1.4e-02 2.9e-03 3.7e-02 4.8e-03
6 NAcc intron excision ratio chr13_34804337_34840383 0.03 0.02 6.3e-03 -0 0 0.01 -0 5.6e-01 3.3e-01 3.9e-02 5.0e-01
7 BLA gene expression LOC120096233 0.19 0.1 1.1e-06 0.05 0.08 0.14 0.1 8.5e-04 6.3e-05 1.3e-07 4.7e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.71.23.50.90.90.20.81.1-1.01.9
Area under the delay curve1.21.42.6-1.3-0.9-1.6-1.1-1.6-0.7-0.6
BMI with tail2.27.410.1-3.0-2.5-3.0-3.1-2.6-3.2-0.9
BMI without tail0.72.23.3-1.7-1.4-1.6-1.8-1.3-1.7-0.1
Body weight0.52.24.3-1.5-1.3-1.5-1.5-1.1-2.1-1.1
Weight adjusted by age0.71.11.5-0.9-1.0-1.2-0.6-1.1-1.21.1
Bone surface0.40.72.7-0.7-0.5-0.9-0.7-0.3-1.60.8
Bone volume0.30.62.30.50.5-0.10.40.6-1.01.5
Breakpoint value in progressive ratio session0.20.20.70.30.7-0.00.0-0.30.80.3
Number of licking bursts0.10.20.7-0.2-0.4-0.6-0.3-0.80.3-0.5
Context. condit. distance diff. score0.30.40.7-0.5-0.6-0.1-0.6-0.70.9-0.7
Locomotion velocity, session 11.51.63.1-1.2-1.4-0.9-1.1-1.80.6-1.4
Locomotion distance, session 10.20.31.50.00.10.20.1-0.51.2-0.6
Locomotion velocity, session 21.11.32.01.41.40.81.41.00.90.9
Locomotion distance, session 20.10.10.30.40.5-0.10.50.1-0.00.5
Locomotion velocity, session 30.50.62.00.1-0.00.80.10.11.4-1.3
Locomotion distance, session 30.20.20.5-0.4-0.5-0.0-0.40.1-0.7-0.7
Stereotopy head waving bouts, day 30.20.20.60.40.40.20.40.5-0.20.8
Stereotopy head waving duration, day 30.20.31.50.0-0.00.40.0-0.21.2-0.4
Locomotion velocity, session 70.80.93.3-0.1-0.31.1-0.1-0.11.8-1.2
Locomotion distance, session 70.00.00.1-0.1-0.40.1-0.1-0.20.2-0.0
Stereotopy head waving bouts, day 70.70.81.20.91.10.90.80.90.70.9
Stereotopy head waving duration, day 70.20.20.70.20.40.70.20.20.90.0
Locomotion velocity, session 81.11.44.4-0.2-0.20.8-0.1-0.42.1-2.1
Locomotion distance, session 80.10.10.4-0.10.00.1-0.0-0.30.6-0.3
Degree of sensitization distance0.20.20.70.10.1-0.30.1-0.50.30.9
Degree of sensitization stereotypy1.11.21.91.01.41.20.91.10.81.0
Conditioned locomotion0.20.20.6-0.3-0.8-0.5-0.2-0.5-0.2-0.7
Cocaine response after cond. corrected4.65.58.5-2.5-2.8-1.9-2.5-2.90.1-2.5
Cocaine response after cond. not corrected5.46.39.3-2.6-2.9-1.6-2.7-3.10.7-3.0
Cocaine response before conditioning0.10.20.40.20.20.50.00.30.7-0.5
Saline control response0.30.51.10.70.50.60.80.51.00.3
Bone: connectivity density0.30.42.1-0.3-0.2-0.5-0.30.2-1.50.7
Bone: cortical apparent density1.21.72.71.61.60.71.41.30.21.5
Bone: cortical area0.81.22.40.91.01.51.01.30.90.8
Bone: cortical porosity0.10.10.2-0.4-0.40.0-0.4-0.0-0.1-0.4
Bone: cortical porosity0.10.10.3-0.3-0.30.3-0.3-0.10.4-0.5
Bone: cortical thickness0.91.42.71.11.21.61.11.51.00.5
Bone: cortical thickness1.82.13.11.61.51.71.51.80.81.1
Bone: cortical tissue density1.11.52.41.61.50.61.31.20.21.5
Condit. Reinf. active minus inactive responses0.80.92.4-0.6-0.7-1.2-0.7-0.6-1.50.7
Condit. Reinf. active-inactive response ratio0.00.00.2-0.1-0.40.1-0.1-0.20.3-0.2
Condit. Reinf. active responses1.01.34.2-0.4-0.4-1.5-0.4-0.5-2.01.4
Condit. Reinf. inactive responses1.01.24.3-0.10.1-1.3-0.1-0.1-2.11.5
Incentive salience index mean0.70.93.5-0.0-0.0-1.0-0.10.0-1.91.3
Condit. Reinf. lever presses0.50.62.40.20.4-0.70.20.3-1.61.2
Condit. Reinf. active minus inactive responses4.96.49.0-3.0-2.8-2.5-3.0-2.6-1.7-1.8
Condit. Reinf. active-inactive response ratio3.94.66.1-2.5-2.4-2.3-2.4-2.4-1.3-1.1
Condit. Reinf. active responses4.56.38.3-2.9-2.8-2.6-2.9-2.5-2.1-1.5
Condit. Reinf. inactive responses0.60.82.8-0.8-0.8-0.9-0.8-0.4-1.70.0
Condit. Reinf. lever presses0.50.71.0-1.0-1.0-0.6-1.0-0.7-0.6-0.7
Condit. Reinf. lever reinforcers received4.25.87.5-2.7-2.7-2.5-2.7-2.4-2.1-1.4
Conditioned reinforcement - actives1.01.82.6-1.5-1.5-1.6-0.8-1.3-1.4-0.7
Conditioned reinforcement - inactives0.71.04.10.50.8-0.01.10.7-0.82.0
Conditioned locomotion0.70.92.80.71.10.41.00.9-0.21.7
Patch foraging indifference point 0 sec2.24.18.31.61.92.71.81.92.90.2
Patch foraging indifference point AUC0.50.71.71.01.30.40.81.10.00.5
Delay disc. indifference point, 0s delay0.70.71.40.91.00.31.00.50.61.2
Delay disc. indifference point, 16s delay5.66.18.7-2.6-2.6-2.9-2.6-2.9-1.8-1.4
Delay disc. indifference point, 2s delay1.92.24.81.41.41.71.51.12.2-0.2
Delay disc. indifference point, 24s delay0.40.51.2-0.5-0.1-1.1-0.5-0.6-1.1-0.2
Delay disc. indifference point, 4s delay0.40.40.9-0.8-0.3-0.9-0.5-0.8-0.70.4
Delay disc. indifference point, 8s delay0.81.01.9-0.9-0.7-1.1-0.8-1.4-0.1-1.4
Indifference point function ln k0.30.51.2-0.8-1.10.1-0.7-0.80.6-0.7
Indifference point function log k0.30.51.2-0.8-1.10.1-0.7-0.80.6-0.7
Patch foraging total patch changes 0 sec1.83.46.61.51.82.51.71.72.60.4
Patch foraging total patch changes 12 sec2.93.75.01.92.22.22.02.02.00.9
Patch foraging total patch changes 18 sec2.94.45.52.12.32.22.22.12.41.3
Patch foraging total patch changes 24 sec1.22.04.50.91.51.91.01.22.1-0.7
Patch foraging total patch changes 6 sec1.82.74.71.51.91.91.61.52.2-0.2
Patch foraging time to switch 0 sec0.61.22.2-0.8-1.2-1.5-0.8-1.3-1.10.3
Patch foraging water rate 0 sec1.02.06.20.00.52.0-0.00.72.5-1.8
Patch foraging water rate 12 sec0.20.41.10.10.61.00.20.70.8-0.3
Patch foraging water rate 18 sec0.60.93.3-0.20.11.20.20.41.3-1.8
Patch foraging water rate 24 sec1.11.64.9-1.4-1.3-0.3-1.1-1.10.4-2.2
Patch foraging water rate 6 sec0.30.41.3-0.40.11.1-0.30.50.9-0.2
Seeking ratio, delayed vs. immediate footshock0.30.30.9-0.6-0.10.3-0.4-0.30.8-1.0
Distance traveled before self-admin0.91.11.51.21.10.91.10.90.91.2
Distance traveled after self-admin3.44.26.62.42.61.72.62.11.01.6
Extensor digitorum longus weight0.52.04.01.51.60.11.61.2-0.92.0
Bone: elastic displacement0.60.72.3-0.8-0.8-0.5-0.7-0.6-0.1-1.5
Bone: elastic work0.81.12.30.70.61.40.70.91.5-1.0
Bone: endosteal estimation0.00.00.1-0.00.20.3-0.00.10.20.4
Bone: endosteal perimeter0.10.10.5-0.3-0.2-0.2-0.2-0.40.00.7
Epididymis fat weight1.96.59.9-2.8-2.2-3.2-2.6-2.8-2.3-1.7
Delta time in closed arm before/after self-admin5.24.87.4-2.4-1.9-2.2-2.4-2.7-0.7-2.4
Delta time in open arm before/after self-admin4.64.511.62.32.21.32.02.10.33.4
Diff in mean of infusions in LGA sessions0.20.20.6-0.5-0.60.5-0.4-0.20.8-0.3
Delay discount exponential model param1.11.32.41.20.91.41.11.60.60.7
Extinction: sum of active levers before priming1.71.96.01.51.50.61.10.90.62.4
Active lever presses in extinction session 61.41.42.61.31.50.71.61.30.10.9
Bone: final force1.62.65.21.51.62.31.51.91.60.4
Bone: final moment1.62.55.21.41.52.31.41.81.60.2
Food consumed during 24 hour testing period0.10.10.3-0.3-0.1-0.3-0.3-0.2-0.50.6
Glucose3.96.28.0-2.8-2.8-2.8-2.8-2.8-2.1-0.2
Heart weight0.91.42.4-1.4-1.4-1.1-1.5-1.1-0.9-0.5
Delay discount hyperbolic model param0.80.91.91.00.71.10.91.40.30.7
Intermittent access intake day 1-15 change0.20.51.20.6-0.20.61.10.70.2-0.7
Intermittent access intake escalation0.40.71.60.90.01.01.30.90.8-0.4
Intermittent access intake escalation 20.30.40.90.6-0.10.80.50.51.0-0.4
Intermitt. access day 1 inactive lever presses1.14.17.92.82.10.92.52.00.02.4
Intermitt. access day 15 inactive lever presses0.20.41.10.70.3-0.50.70.4-0.71.0
Intermitt. access escalation Index0.00.00.10.2-0.00.1-0.00.10.30.1
Intermittent access day 1 total infusions0.20.30.8-0.9-0.2-0.6-0.9-0.6-0.3-0.2
Intermittent access day 15 total infusions0.20.30.50.50.40.60.50.70.50.3
Intermittent access terminal intake (last 3 days)0.10.20.50.30.40.50.20.40.70.0
Intermittent access total infusions0.10.10.3-0.40.0-0.3-0.6-0.1-0.20.4
Intermittent access day 1 locomotion0.91.12.31.31.50.80.81.01.10.4
Intermittent access day 15 total locomotion0.50.81.60.60.80.80.60.71.3-1.3
Intermittent access total locomotion1.21.42.31.31.41.20.81.11.50.6
Intermittent access standard deviation0.10.20.40.6-0.1-0.00.5-0.10.6-0.4
Left kidney weight0.62.96.31.72.0-0.21.51.6-1.52.5
Right kidney weight0.73.05.31.92.00.51.91.8-0.92.3
Cocaine induced anxiety0.10.10.4-0.1-0.4-0.40.2-0.2-0.60.5
Post-drug Anxiety0.20.20.9-0.1-0.9-0.30.3-0.3-0.40.3
Baseline Anxiety0.10.10.50.0-0.7-0.1-0.2-0.10.1-0.2
Tail length0.20.81.60.90.81.30.81.01.10.1
Length with tail0.10.20.60.30.10.50.40.50.4-0.8
Length without tail0.10.51.9-0.7-0.5-0.4-0.4-0.4-0.4-1.4
Times rat made contact with spout0.80.91.21.11.00.91.01.10.31.0
Lifetime Intake0.10.20.6-0.40.2-0.4-0.4-0.2-0.30.8
Liver weight, left0.91.52.51.31.20.81.41.6-0.71.3
Liver weight, right0.10.20.80.20.1-0.7-0.10.1-0.9-0.5
Locomotor activity0.50.83.5-0.2-0.1-0.9-0.10.1-1.91.2
Locomotor testing distance0.30.51.30.10.2-0.60.40.2-1.21.1
Locomotor testing rearing0.20.50.80.70.8-0.10.90.7-0.80.4
Locomotion in novel chamber0.81.02.41.10.81.11.00.71.6-0.3
Locomotion in novel chamber post-restriction0.00.10.20.30.20.00.20.00.30.4
Fecal boli incidents, locomotor time 12.53.66.5-1.6-1.7-2.6-1.8-1.8-2.50.6
Change in fecal boli incidents, locomotor task2.52.43.31.81.51.51.81.80.71.5
Time >=10cm from walls, locomotor time 10.40.41.20.20.50.10.30.5-1.01.1
Bouts of movement, locomotor time 10.20.20.4-0.4-0.3-0.7-0.4-0.4-0.6-0.4
Total resting periods, locomotor time 10.60.61.2-0.8-0.6-1.0-0.8-0.6-1.1-0.5
Rest time, locomotor task time 10.70.91.2-1.1-0.9-0.9-1.1-0.9-1.1-0.5
Distance moved, locomotor task time 11.21.84.41.51.31.21.50.72.10.4
Vertical activity count, locomotor time 11.84.47.22.12.32.22.21.82.70.8
Time >=10cm from walls, locomotor time 20.20.20.50.10.20.50.10.7-0.50.7
Bouts of movement, locomotor time 20.91.42.3-1.2-1.1-1.5-1.2-1.4-0.6-1.0
Total resting periods, locomotor time 20.71.22.9-1.1-0.9-1.7-1.1-1.3-0.8-0.6
Rest time, locomotor task time 20.81.02.0-0.8-0.9-1.4-0.9-1.0-1.20.1
Distance moved, locomotor task time 22.73.34.41.91.92.01.91.72.10.6
Vertical activity count, locomotor time 21.01.42.60.91.41.50.91.11.60.1
Light reinforcement 10.51.13.70.10.3-0.70.20.4-1.91.8
Light reinforcement 20.60.93.3-0.7-1.0-1.0-0.8-0.3-1.8-0.1
Bone: marrow area0.00.10.20.10.30.40.00.20.30.3
Bone: maximum diameter0.30.61.30.70.70.70.80.70.21.2
Bone: maximum force2.34.28.41.81.92.91.82.22.30.3
Bone: maximum moment2.23.87.91.71.92.81.72.12.20.2
Mean time between licks in bursts2.25.47.6-2.6-2.8-2.1-2.5-2.5-1.0-2.3
Mean num. licks in bursts0.60.91.80.91.01.00.91.3-0.11.2
Cd content in liver0.10.10.2-0.2-0.3-0.3-0.2-0.40.00.1
Co content in liver1.31.52.6-1.6-1.6-0.2-1.5-0.8-0.4-1.6
Cu content in liver4.24.97.62.62.52.22.62.80.81.4
Fe content in liver0.10.10.3-0.2-0.10.4-0.20.00.6-0.3
K content in liver0.20.20.50.40.50.20.40.7-0.50.4
Mg content in liver0.10.10.10.00.30.3-0.00.4-0.1-0.3
Mn content in liver1.01.11.81.31.20.91.21.30.10.8
Na content in liver2.12.33.3-1.6-1.4-1.8-1.6-1.4-1.8-0.9
Rb content in liver1.01.12.7-1.3-1.0-0.2-1.3-0.7-0.4-1.6
Se content in liver0.30.40.9-0.5-0.4-0.8-0.6-0.3-0.90.3
Sr content in liver1.81.62.1-1.2-1.4-1.5-1.2-1.2-1.4-0.6
Zn content in liver0.60.72.30.30.2-0.70.20.1-1.31.5
Bone: minimum diameter0.20.31.20.10.31.10.20.70.50.2
Time in familiar zone, hab. session 11.21.12.2-1.0-1.3-0.4-0.9-1.30.7-1.5
Time in novel zone, hab. session 10.80.82.50.50.5-0.40.50.6-1.41.6
Total zone transitions, hab. session 10.10.10.70.2-0.10.30.40.00.8-0.1
Total locomotion distance, hab. session 10.10.20.60.50.3-0.00.60.10.20.8
Locomotion velocity, hab. session 10.30.40.70.70.70.40.80.50.40.7
Time in familiar zone, hab. session 22.32.46.4-1.4-1.7-0.3-1.4-1.71.1-2.5
Time in novel zone, hab. session 21.41.55.00.81.0-0.20.81.0-1.32.2
Total zone transitions, hab. session 20.10.10.60.0-0.10.20.10.10.3-0.8
Total locomotion distance, hab. session 20.20.20.50.50.4-0.10.60.4-0.40.7
Locomotion velocity, hab. session 20.30.40.70.70.70.20.80.7-0.20.6
Novel to familiar place preference ratio0.70.72.70.40.4-0.40.40.4-1.31.6
Novelty place preference0.80.93.30.60.6-0.20.70.6-1.11.8
Time in novel zone, NPP test0.80.93.20.70.7-0.20.70.7-1.11.8
Total zone transitions, NPP test0.71.01.5-1.0-1.1-0.9-1.0-1.1-0.1-1.2
Total locomotion distance, NPP test0.30.41.20.10.2-0.90.2-0.1-1.11.0
Locomotion velocity, NPP test0.20.31.10.00.0-0.80.1-0.2-1.00.8
Intraocular pressure0.30.51.2-0.1-0.3-1.1-0.2-0.5-1.10.8
Delta distance traveled before/after self-admin0.80.81.60.81.30.91.21.00.3-0.3
Delta ambulatory time before/after self-admin0.70.91.91.11.20.81.41.00.20.2
Parametrial fat weight1.94.68.7-1.9-2.0-2.8-1.9-2.0-3.00.5
Pavlov. Cond. lever latency0.10.10.3-0.2-0.5-0.2-0.2-0.50.1-0.1
Pavlov. Cond. magazine entry latency0.00.00.1-0.2-0.40.1-0.10.00.0-0.2
Pavlov. Cond. change in total contacts0.40.42.00.00.2-0.40.10.5-1.40.6
Pavlov. Cond. index score0.00.00.10.00.10.30.10.30.2-0.1
Pavlov. Cond. latency score0.00.00.1-0.1-0.00.2-0.10.20.1-0.3
Pavlov. Cond. lever contacts0.20.20.60.40.60.50.40.8-0.1-0.0
Pavlov. Cond. magazine entry number0.10.10.2-0.10.0-0.5-0.2-0.4-0.3-0.0
Pavlov. Cond. intertrial magazine entries0.30.30.5-0.5-0.6-0.7-0.6-0.7-0.5-0.5
Pavlov. Cond. lever-magazine prob. diff.0.10.10.20.30.30.40.30.50.10.2
Pavlov. Cond. response bias0.10.10.30.30.30.20.30.5-0.20.4
Pavlov. Cond. lever latency0.30.40.90.70.60.70.60.31.00.3
Pavlov. Cond. magazine entry latency0.10.10.4-0.3-0.00.3-0.20.00.6-0.6
Pavlov. Cond. change in total contacts0.61.01.7-1.0-1.1-1.1-1.0-0.8-1.3-0.4
Pavlov. Cond. index score0.10.10.3-0.4-0.4-0.3-0.4-0.1-0.5-0.4
Pavlov. Cond. latency score0.00.00.2-0.1-0.00.2-0.10.2-0.1-0.4
Pavlov. Cond. lever contacts0.30.40.8-0.7-0.6-0.7-0.7-0.4-0.9-0.4
Pavlov. Cond. magazine entry number0.00.00.10.20.00.20.2-0.00.30.2
Pavlov. Cond. intertrial magazine entries0.91.31.9-1.3-1.4-1.1-1.3-1.3-0.6-1.0
Pavlov. Cond. lever-magazine prob. diff.0.10.20.2-0.5-0.4-0.3-0.5-0.2-0.4-0.5
Pavlov. Cond. response bias0.30.40.9-0.6-0.5-0.9-0.6-0.4-1.0-0.0
Time in closed arm before self-admin1.21.52.51.40.81.51.61.60.6-0.0
Time in closed arm after self-admin0.80.93.9-0.8-0.9-0.4-0.5-0.7-0.1-2.0
Time in open arm before self-admin1.51.63.3-1.7-0.9-0.8-1.8-1.5-0.0-1.1
Time in open arm after self-admin1.01.14.30.51.30.60.30.9-0.12.1
Bone: periosteal estimation0.20.51.10.40.71.10.50.70.80.6
Bone: periosteal perimeter0.10.21.1-0.10.10.60.0-0.11.0-0.0
Bone: post-yield work0.30.41.0-1.0-0.6-0.1-1.0-0.6-0.0-0.5
Progressive ratio test 1 active lever presses0.70.91.3-1.1-0.7-1.1-1.0-0.9-0.8-0.8
Progressive ratio test 1 breakpoint0.81.01.4-1.2-0.8-1.2-1.0-1.0-0.8-0.8
Progressive ratio test 1 inactive lever presses0.60.92.01.21.2-0.11.40.7-0.21.0
Progressive ratio test 2 active lever presses0.20.20.5-0.6-0.30.1-0.5-0.20.3-0.7
Progressive ratio test 2 breakpoint0.20.20.4-0.6-0.20.1-0.5-0.20.4-0.7
Progressive ratio test 2 inactive lever presses1.42.23.31.41.81.31.81.60.31.6
Incentive Sensitization - Responses0.20.41.4-0.6-0.50.3-0.3-0.20.5-1.2
Incentive Sensitization - Breakpoint0.20.31.3-0.4-0.30.5-0.20.00.6-1.1
Sum of active levers in priming session hrs 5-62.52.35.41.72.31.11.41.50.81.4
Progressive ratio0.30.52.4-0.00.30.9-0.00.11.6-0.4
Food seeking constrained by brief footshock0.50.61.50.30.51.20.80.90.5-1.0
Seeking ratio, punishment vs. effort0.20.32.0-0.2-0.2-0.20.10.2-1.4-0.1
Retroperitoneal fat weight7.833.246.4-6.8-6.1-5.7-6.6-6.1-4.5-3.9
Reaction time number correct0.40.81.6-1.3-1.1-0.7-1.1-0.9-0.4-0.2
Reaction time mean minus median1.94.79.5-1.9-2.0-3.1-2.1-2.6-2.10.1
Reaction time mean minus median AUC2.25.79.2-2.3-2.5-3.0-2.6-2.9-1.9-0.7
Reaction time num false alarms0.81.12.80.00.21.40.10.71.4-1.7
Reaction time num false alarms AUC0.71.12.40.50.61.50.51.01.4-1.2
Reaction time trials correct on left0.40.81.6-1.3-1.1-0.7-1.1-0.9-0.4-0.2
Reaction time trials on left0.50.91.8-1.3-1.1-0.7-1.1-1.0-0.4-0.3
Reaction time mean1.11.84.9-0.0-0.4-1.8-0.5-0.8-1.92.2
Reaction time mean AUC1.32.14.2-0.3-0.8-2.0-0.8-1.1-2.02.0
Median of all reaction times0.91.35.90.50.1-1.10.1-0.2-1.32.4
Reaction time omissions0.91.32.0-0.9-1.2-1.4-1.1-1.3-0.9-0.8
Reaction time false alarm rate0.70.91.80.70.71.30.61.01.1-1.1
Reaction time premature initiation rate0.20.21.10.1-0.1-0.60.3-0.2-1.1-0.2
Reaction time premature initiations0.20.30.8-0.4-0.5-0.7-0.2-0.5-0.9-0.4
Std. dev. reaction times1.52.75.7-1.2-1.4-2.4-1.6-1.9-1.90.5
Reaction time trials completed0.50.91.8-1.3-1.1-0.7-1.1-1.0-0.4-0.3
Reaction time trials AUC0.40.81.7-1.3-1.1-0.7-1.1-1.0-0.3-0.4
Run reversals in cocaine runway, females3.03.010.3-1.6-1.7-0.3-1.2-1.51.1-3.2
Run reversals in cocaine runway, males0.10.10.30.00.00.50.10.30.1-0.5
Latency to leave start box in cocaine runway0.30.31.10.20.5-0.10.10.5-1.10.9
Latency to leave start box in cocaine runway, F0.10.10.2-0.5-0.1-0.2-0.4-0.2-0.40.1
Latency to leave start box in cocaine runway, M1.61.52.81.31.20.21.11.3-1.21.7
Std. dev. time between licks in bursts2.33.24.3-2.1-2.1-1.3-2.1-1.8-0.8-2.0
Total sessions with >9 infusions0.10.10.10.30.3-0.30.3-0.10.10.3
Short access day 1 total inactive lever presses1.11.52.91.21.70.01.51.0-0.61.5
Short access day 10 total inactive lever presses0.92.36.1-0.5-1.6-2.5-0.6-1.6-1.9-0.0
Short access day 1 total infusions0.20.31.60.10.6-0.20.4-0.0-0.01.3
Short access day 10 total infusions0.10.10.40.10.5-0.40.2-0.30.30.7
Short access total infusions0.40.41.1-0.7-0.1-1.1-0.5-0.7-0.70.6
Short access day 1 locomotion0.40.51.90.90.4-0.20.80.20.31.4
Short access day 10 total locomotion1.01.83.31.81.21.21.71.11.5-0.0
Short access total locomotion0.50.61.61.30.8-0.11.00.40.31.0
One hour access (0.3 mA shock)0.91.01.7-1.3-0.6-1.1-1.2-0.9-1.20.1
Compulsive drug intake0.50.61.70.10.3-1.3-0.3-0.3-1.20.8
One hour access (shock baseline)0.10.20.4-0.6-0.20.6-0.3-0.00.30.5
Social response proportion0.50.61.7-0.7-0.80.6-0.8-0.41.3-0.4
Social responses0.20.20.7-0.3-0.50.6-0.3-0.00.8-0.3
Social time0.60.81.9-0.8-1.1-0.1-0.8-0.90.8-1.4
Soleus weight1.95.58.72.92.91.42.82.50.22.2
Bone: stiffness1.82.94.31.81.82.11.71.91.41.2
Tibialis anterior weight0.10.30.7-0.2-0.1-0.7-0.1-0.3-0.90.7
Time to tail flick, vehicle, before self-admin0.70.82.80.30.4-0.20.60.6-1.21.7
Time to tail flick, vehicle, after self-admin0.00.10.20.0-0.3-0.2-0.0-0.1-0.2-0.4
Time to tail flick, test, before self-admin2.82.94.71.71.61.92.21.91.3-0.8
Time to tail flick, test, after self-admin0.10.10.30.40.20.50.50.4-0.0-0.2
Delta time to tail flick, vehicle, before/after SA0.40.41.0-0.2-0.7-0.4-0.6-0.60.4-1.0
Delta time to tail flick, test, before/after SA4.34.46.4-2.2-2.1-2.4-2.5-2.5-1.70.3
Tibia length0.30.82.9-1.0-0.60.4-0.9-0.20.3-1.7
Ambulatory time before self-admin0.60.91.41.11.00.90.80.90.81.2
Ambulatory time after self-admin3.03.55.62.02.41.72.02.00.51.9
Bone: tissue strength0.50.51.1-0.9-0.7-0.2-0.9-0.60.1-1.1
Total heroin consumption1.41.74.81.62.20.71.10.81.01.0
Bone: trabecular number1.11.73.91.51.30.51.41.3-0.32.0
Bone: trabecular spacing2.73.66.2-2.2-1.9-1.0-2.3-2.10.2-2.5
Bone: trabecular thickness5.46.710.53.02.92.52.93.20.92.1
Bone: trabecular tissue density1.01.52.71.31.61.21.11.20.91.2
Water consumed over 24 hours0.91.31.61.21.21.11.11.20.71.3
Number of responses in last shaping day0.40.51.20.90.70.21.10.40.20.9