LOC120095265

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc mRNA stability LOC120095265 0.03 0.03 1.5e-04 0.02 0.02 0.03 0.02 3.2e-04 2.0e-04 1.4e-05 2.4e-04
2 Brain mRNA stability LOC120095265 0.09 0.08 1.4e-07 0.06 0.08 0.08 0.08 2.2e-06 8.5e-08 7.9e-08 8.1e-08
3 OFC gene expression LOC120095265 0.39 0.25 2.4e-07 0.21 0.27 0.2 0.28 1.1e-05 3.1e-07 1.5e-05 2.9e-07
4 Adipose gene expression LOC120095265 0.19 0.11 0.0e+00 0.18 0.18 0.17 0.17 1.0e-19 1.9e-19 1.6e-18 1.3e-18
5 pVTA gene expression LOC120095265 0.13 0.12 5.8e-10 0.1 0.12 0.11 0.12 8.6e-09 6.7e-10 2.0e-09 1.3e-09
6 IL gene expression LOC120095265 0.41 0.25 2.9e-08 0.26 0.32 0.29 0.3 6.7e-07 1.9e-08 1.4e-07 5.1e-08
7 Brain gene expression LOC120095265 0.11 0.1 5.5e-09 0.08 0.09 0.09 0.09 2.9e-08 4.1e-09 4.5e-09 6.2e-09
8 PL gene expression LOC120095265 0.16 0.14 8.3e-16 0.09 0.15 0.12 0.12 2.0e-10 7.0e-16 2.5e-13 6.6e-13
9 NAcc gene expression LOC120095265 0.19 0.16 0.0e+00 0.16 0.17 0.16 0.17 1.0e-23 1.9e-25 5.4e-24 5.0e-25
10 IC gene expression LOC120095265 0.2 0.16 7.2e-07 0.16 0.13 0.17 0.12 4.5e-07 5.1e-06 1.8e-07 6.5e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density2.03.74.3-1.8-2.02.12.01.91.91.91.91.9-1.8
Area under the delay curve1.92.93.31.51.8-1.8-1.7-1.8-1.8-1.8-1.8-1.81.5
BMI with tail1.65.46.0-2.4-2.42.22.32.42.42.42.42.3-2.2
BMI without tail1.26.67.2-2.7-2.62.62.62.62.62.62.62.5-2.5
Body weight2.611.513.7-3.7-3.63.63.33.33.33.33.33.3-3.4
Weight adjusted by age0.10.20.4-0.6-0.50.50.50.50.50.50.50.5-0.2
Bone surface1.42.72.9-1.5-1.61.71.71.71.71.71.71.7-1.5
Bone volume1.22.53.2-1.5-1.71.81.61.51.51.51.51.5-1.5
Breakpoint value in progressive ratio session0.61.11.4-1.2-1.01.01.01.11.01.01.01.1-1.0
Number of licking bursts0.10.30.50.50.5-0.7-0.5-0.5-0.5-0.5-0.5-0.50.6
Context. condit. distance diff. score0.60.71.1-0.8-0.91.10.80.80.80.80.80.8-0.8
Locomotion velocity, session 11.82.02.4-1.3-1.10.91.51.51.51.51.51.5-1.5
Locomotion distance, session 10.20.20.4-0.5-0.2-0.10.50.50.50.50.50.6-0.6
Locomotion velocity, session 20.00.10.1-0.3-0.1-0.10.20.30.30.30.30.3-0.3
Locomotion distance, session 20.91.31.6-1.0-1.00.71.31.31.31.31.31.3-1.0
Locomotion velocity, session 32.83.23.51.71.6-1.6-1.9-1.8-1.8-1.8-1.8-1.91.9
Locomotion distance, session 30.40.40.50.60.5-0.5-0.7-0.7-0.7-0.7-0.7-0.70.6
Stereotopy head waving bouts, day 30.00.00.00.1-0.0-0.10.20.10.10.10.10.2-0.0
Stereotopy head waving duration, day 30.40.50.80.90.8-0.9-0.5-0.6-0.6-0.6-0.6-0.60.7
Locomotion velocity, session 70.50.60.8-0.9-0.90.80.70.70.70.70.70.7-0.7
Locomotion distance, session 70.60.80.9-0.9-0.90.80.80.90.90.90.90.9-0.9
Stereotopy head waving bouts, day 70.50.60.7-0.7-0.80.90.80.80.80.80.80.8-0.5
Stereotopy head waving duration, day 70.20.30.4-0.4-0.50.50.60.60.60.60.60.6-0.4
Locomotion velocity, session 80.00.00.1-0.1-0.40.30.10.10.10.10.10.1-0.1
Locomotion distance, session 80.71.01.2-0.9-1.00.91.11.11.11.11.11.1-0.9
Degree of sensitization distance3.23.53.7-1.9-1.81.71.91.91.91.91.91.9-1.8
Degree of sensitization stereotypy0.60.70.9-0.8-0.90.90.80.80.80.80.80.8-0.6
Conditioned locomotion1.11.31.51.11.0-1.0-1.2-1.2-1.2-1.2-1.2-1.21.2
Cocaine response after cond. corrected1.31.92.4-1.5-1.31.21.41.51.41.41.41.4-1.2
Cocaine response after cond. not corrected1.82.63.0-1.7-1.41.41.61.71.71.71.71.6-1.4
Cocaine response before conditioning0.20.20.3-0.3-0.30.20.50.50.50.50.50.5-0.5
Saline control response0.00.00.0-0.00.1-0.1-0.1-0.0-0.0-0.0-0.0-0.00.1
Bone: connectivity density3.65.86.4-2.3-2.52.52.52.42.42.42.42.4-2.2
Bone: cortical apparent density0.20.40.40.60.5-0.5-0.7-0.6-0.6-0.6-0.6-0.60.7
Bone: cortical area1.32.12.21.51.4-1.3-1.5-1.5-1.5-1.5-1.5-1.51.3
Bone: cortical porosity0.20.30.3-0.4-0.60.60.50.50.50.50.50.5-0.5
Bone: cortical porosity0.10.10.1-0.2-0.30.30.30.30.30.30.30.3-0.3
Bone: cortical thickness2.33.84.22.01.8-1.6-2.0-2.0-2.0-2.0-2.0-2.11.9
Bone: cortical thickness0.00.00.00.10.2-0.1-0.1-0.1-0.1-0.1-0.1-0.10.1
Bone: cortical tissue density0.10.20.20.40.3-0.3-0.5-0.4-0.4-0.4-0.4-0.40.5
Condit. Reinf. active minus inactive responses0.60.60.70.80.6-0.6-0.8-0.8-0.8-0.8-0.8-0.80.9
Condit. Reinf. active-inactive response ratio0.10.20.20.40.3-0.2-0.4-0.4-0.4-0.4-0.4-0.40.4
Condit. Reinf. active responses0.00.00.00.00.1-0.1-0.1-0.1-0.1-0.1-0.1-0.10.2
Condit. Reinf. inactive responses0.30.30.4-0.7-0.50.30.60.70.60.60.60.6-0.5
Incentive salience index mean0.20.30.40.50.3-0.3-0.6-0.6-0.6-0.6-0.6-0.60.7
Condit. Reinf. lever presses0.10.20.5-0.5-0.60.70.30.30.30.30.30.3-0.1
Condit. Reinf. active minus inactive responses0.20.20.40.60.5-0.5-0.5-0.5-0.5-0.4-0.4-0.40.5
Condit. Reinf. active-inactive response ratio0.30.50.60.80.6-0.6-0.8-0.7-0.7-0.7-0.7-0.70.8
Condit. Reinf. active responses0.10.10.20.40.3-0.3-0.3-0.3-0.3-0.3-0.3-0.30.3
Condit. Reinf. inactive responses0.10.10.2-0.3-0.30.50.40.30.30.30.30.3-0.4
Condit. Reinf. lever presses2.53.64.22.11.9-1.9-1.9-1.9-1.9-1.9-1.9-1.81.8
Condit. Reinf. lever reinforcers received0.30.40.60.80.6-0.5-0.6-0.6-0.6-0.6-0.6-0.60.6
Conditioned reinforcement - actives0.10.30.4-0.6-0.60.60.50.50.50.50.50.5-0.3
Conditioned reinforcement - inactives0.00.10.2-0.2-0.10.10.30.20.30.30.30.3-0.4
Conditioned locomotion0.10.10.2-0.3-0.40.50.40.30.30.30.30.3-0.2
Patch foraging indifference point 0 sec0.20.50.50.60.7-0.7-0.7-0.7-0.7-0.7-0.7-0.70.6
Patch foraging indifference point AUC1.23.03.71.61.7-1.9-1.8-1.6-1.7-1.7-1.7-1.71.9
Delay disc. indifference point, 0s delay1.21.31.71.21.3-1.2-1.1-1.1-1.1-1.1-1.1-1.11.0
Delay disc. indifference point, 16s delay1.72.43.01.31.7-1.7-1.5-1.6-1.6-1.6-1.6-1.61.4
Delay disc. indifference point, 2s delay2.62.93.21.61.8-1.7-1.7-1.8-1.8-1.8-1.8-1.81.4
Delay disc. indifference point, 24s delay0.50.81.1-1.0-1.00.90.80.80.80.80.80.8-0.9
Delay disc. indifference point, 4s delay0.30.30.60.50.8-0.8-0.6-0.6-0.6-0.6-0.6-0.60.1
Delay disc. indifference point, 8s delay0.81.41.70.91.0-1.0-1.3-1.3-1.3-1.3-1.3-1.31.3
Indifference point function ln k0.30.91.4-0.9-0.91.21.00.90.90.90.90.9-1.1
Indifference point function log k0.30.91.4-0.9-0.91.21.00.90.90.90.90.9-1.1
Patch foraging total patch changes 0 sec0.10.30.40.50.6-0.6-0.6-0.6-0.6-0.6-0.6-0.60.5
Patch foraging total patch changes 12 sec0.20.30.40.40.4-0.6-0.5-0.5-0.5-0.5-0.5-0.50.5
Patch foraging total patch changes 18 sec0.81.92.31.31.3-1.5-1.4-1.4-1.4-1.4-1.4-1.41.3
Patch foraging total patch changes 24 sec0.93.04.31.71.7-2.1-1.7-1.7-1.7-1.7-1.7-1.71.7
Patch foraging total patch changes 6 sec3.05.15.42.32.3-2.3-2.3-2.2-2.2-2.2-2.2-2.32.3
Patch foraging time to switch 0 sec0.62.22.4-1.4-1.41.41.51.51.51.51.51.5-1.4
Patch foraging water rate 0 sec0.83.14.01.71.8-2.0-1.7-1.8-1.7-1.7-1.7-1.71.6
Patch foraging water rate 12 sec0.10.40.6-0.7-0.80.70.60.60.60.60.60.6-0.7
Patch foraging water rate 18 sec0.20.50.7-0.5-0.80.80.80.70.70.70.70.7-0.7
Patch foraging water rate 24 sec0.20.30.30.60.5-0.6-0.5-0.6-0.6-0.6-0.6-0.50.3
Patch foraging water rate 6 sec0.91.31.51.11.1-1.2-1.1-1.2-1.2-1.2-1.2-1.21.0
Seeking ratio, delayed vs. immediate footshock1.82.63.71.81.4-1.3-1.6-1.6-1.6-1.6-1.6-1.61.9
Distance traveled before self-admin2.14.75.52.42.1-2.1-2.2-2.1-2.1-2.1-2.1-2.12.3
Distance traveled after self-admin0.10.10.40.30.2-0.2-0.4-0.3-0.3-0.3-0.3-0.30.6
Extensor digitorum longus weight0.72.62.8-1.7-1.61.51.71.71.71.71.71.7-1.4
Bone: elastic displacement2.63.33.51.71.8-1.8-1.9-1.9-1.9-1.9-1.9-1.91.7
Bone: elastic work7.49.710.63.13.0-2.8-3.2-3.3-3.3-3.3-3.3-3.32.8
Bone: endosteal estimation0.10.10.40.30.6-0.7-0.2-0.3-0.3-0.3-0.3-0.30.1
Bone: endosteal perimeter0.00.00.10.20.3-0.3-0.0-0.1-0.1-0.1-0.1-0.1-0.0
Epididymis fat weight5.126.027.8-5.3-5.25.25.15.15.15.15.15.0-4.9
Delta time in closed arm before/after self-admin2.62.52.71.51.5-1.5-1.6-1.6-1.6-1.6-1.6-1.61.4
Delta time in open arm before/after self-admin4.45.25.5-2.1-2.42.32.32.32.32.32.32.3-1.9
Diff in mean of infusions in LGA sessions0.40.60.7-0.7-0.80.80.80.80.80.80.80.8-0.8
Delay discount exponential model param1.41.92.2-1.2-1.51.51.41.41.41.41.41.4-1.1
Extinction: sum of active levers before priming0.81.21.5-0.9-0.90.91.21.11.11.11.11.1-1.2
Active lever presses in extinction session 60.60.60.7-0.8-0.70.70.80.80.80.80.80.8-0.8
Bone: final force0.30.50.60.70.6-0.4-0.8-0.8-0.8-0.8-0.8-0.80.6
Bone: final moment0.40.70.80.90.7-0.6-0.8-0.9-0.9-0.9-0.9-0.90.7
Food consumed during 24 hour testing period0.10.10.20.20.4-0.5-0.3-0.4-0.4-0.4-0.4-0.40.1
Glucose1.52.32.61.51.4-1.3-1.6-1.6-1.6-1.6-1.6-1.61.6
Heart weight1.93.03.5-1.9-1.61.71.81.71.71.71.71.7-1.8
Delay discount hyperbolic model param1.82.42.8-1.3-1.61.71.61.61.61.61.61.6-1.2
Intermittent access intake day 1-15 change0.00.00.00.0-0.20.00.10.10.10.10.10.10.1
Intermittent access intake escalation0.00.00.1-0.1-0.30.20.30.20.20.20.20.2-0.0
Intermittent access intake escalation 20.20.30.40.60.5-0.6-0.5-0.5-0.5-0.5-0.5-0.50.7
Intermitt. access day 1 inactive lever presses0.00.30.70.80.6-0.6-0.3-0.5-0.5-0.5-0.5-0.50.5
Intermitt. access day 15 inactive lever presses0.10.81.31.10.9-0.8-0.8-0.8-0.8-0.8-0.8-0.80.8
Intermitt. access escalation Index0.31.01.9-1.4-1.01.01.11.01.01.01.00.9-0.9
Intermittent access day 1 total infusions0.00.10.1-0.3-0.20.30.10.20.20.20.20.2-0.2
Intermittent access day 15 total infusions0.20.60.7-0.6-0.90.80.80.80.80.80.80.8-0.6
Intermittent access terminal intake (last 3 days)0.40.71.0-0.8-1.01.00.80.90.90.90.90.9-0.7
Intermittent access total infusions0.10.10.3-0.1-0.40.50.30.30.30.30.30.3-0.0
Intermittent access day 1 locomotion0.00.00.00.1-0.00.1-0.1-0.0-0.0-0.0-0.0-0.00.1
Intermittent access day 15 total locomotion0.10.30.4-0.5-0.60.60.50.50.50.50.50.5-0.4
Intermittent access total locomotion0.30.40.7-0.5-0.70.80.50.60.60.60.60.6-0.4
Intermittent access standard deviation0.00.10.20.40.1-0.1-0.2-0.2-0.2-0.2-0.2-0.20.3
Left kidney weight0.10.40.8-0.8-0.80.90.60.50.50.50.50.5-0.7
Right kidney weight0.10.71.5-0.9-1.11.20.70.70.70.70.70.7-0.8
Cocaine induced anxiety0.10.20.20.40.5-0.4-0.5-0.5-0.5-0.5-0.5-0.40.3
Post-drug Anxiety0.20.30.3-0.4-0.50.60.50.50.50.50.50.5-0.4
Baseline Anxiety0.30.60.6-0.6-0.80.80.80.80.80.80.80.8-0.6
Tail length0.42.33.7-1.8-1.71.91.41.41.41.41.41.3-1.5
Length with tail0.73.14.9-2.1-2.02.21.61.51.51.51.51.5-1.8
Length without tail0.21.11.7-1.3-1.31.30.80.90.80.90.90.8-1.0
Times rat made contact with spout0.00.00.1-0.3-0.00.10.00.10.10.10.10.1-0.1
Lifetime Intake0.10.20.3-0.2-0.50.60.40.50.40.40.40.4-0.2
Liver weight, left4.78.110.1-3.0-3.13.22.72.82.72.72.82.7-2.6
Liver weight, right4.37.59.5-3.1-3.03.12.62.62.62.62.62.6-2.6
Locomotor activity0.10.10.60.40.5-0.8-0.3-0.3-0.3-0.3-0.3-0.30.2
Locomotor testing distance0.10.20.80.40.5-0.9-0.4-0.4-0.4-0.4-0.4-0.40.6
Locomotor testing rearing0.00.10.40.20.4-0.7-0.1-0.1-0.1-0.1-0.1-0.10.2
Locomotion in novel chamber2.83.84.72.01.9-1.8-1.9-1.9-1.9-1.9-1.9-2.02.2
Locomotion in novel chamber post-restriction0.00.00.40.3-0.10.00.00.10.10.10.10.00.6
Fecal boli incidents, locomotor time 11.02.63.5-1.7-1.91.91.61.61.61.61.61.6-1.4
Change in fecal boli incidents, locomotor task0.30.30.40.60.6-0.6-0.6-0.6-0.6-0.6-0.6-0.60.3
Time >=10cm from walls, locomotor time 10.00.00.0-0.1-0.10.10.20.10.20.20.10.1-0.1
Bouts of movement, locomotor time 10.50.60.90.80.9-1.0-0.8-0.8-0.8-0.8-0.7-0.70.7
Total resting periods, locomotor time 10.10.10.30.30.4-0.5-0.3-0.3-0.3-0.3-0.3-0.30.3
Rest time, locomotor task time 10.20.30.4-0.4-0.50.40.60.60.60.60.60.6-0.6
Distance moved, locomotor task time 10.30.81.10.91.1-1.0-0.8-0.8-0.8-0.8-0.8-0.80.8
Vertical activity count, locomotor time 10.10.40.40.70.6-0.6-0.6-0.6-0.6-0.6-0.6-0.60.6
Time >=10cm from walls, locomotor time 20.30.91.2-0.8-0.90.91.00.90.90.90.90.9-1.1
Bouts of movement, locomotor time 20.10.40.70.60.7-0.8-0.6-0.6-0.6-0.6-0.6-0.60.2
Total resting periods, locomotor time 20.00.10.20.20.3-0.4-0.2-0.2-0.2-0.2-0.2-0.2-0.1
Rest time, locomotor task time 20.10.20.2-0.3-0.50.40.40.40.40.40.40.4-0.4
Distance moved, locomotor task time 20.70.91.21.01.1-1.1-0.9-0.9-0.9-0.9-0.9-0.91.0
Vertical activity count, locomotor time 20.61.41.71.21.3-1.3-1.2-1.2-1.2-1.2-1.2-1.21.1
Light reinforcement 10.00.00.20.1-0.1-0.0-0.2-0.2-0.2-0.2-0.2-0.20.4
Light reinforcement 20.30.60.80.70.8-0.9-0.7-0.7-0.8-0.8-0.8-0.80.7
Bone: marrow area0.10.10.50.30.6-0.7-0.2-0.3-0.3-0.3-0.3-0.30.1
Bone: maximum diameter0.40.91.11.01.1-1.0-0.9-0.9-0.9-0.9-0.9-0.90.8
Bone: maximum force0.51.01.11.00.9-0.8-1.0-1.1-1.1-1.1-1.1-1.10.9
Bone: maximum moment0.71.31.51.21.1-1.0-1.1-1.2-1.2-1.2-1.2-1.21.0
Mean time between licks in bursts0.21.01.4-1.2-0.91.11.01.01.01.01.01.0-0.9
Mean num. licks in bursts0.20.50.8-0.9-0.70.80.70.70.70.70.70.6-0.7
Cd content in liver0.80.91.40.81.0-1.2-1.0-0.9-0.9-0.9-0.9-0.90.8
Co content in liver0.30.30.50.40.5-0.6-0.6-0.5-0.5-0.5-0.5-0.50.7
Cu content in liver1.31.51.81.21.3-1.3-1.2-1.2-1.2-1.2-1.2-1.21.1
Fe content in liver1.92.42.5-1.5-1.51.51.61.61.61.61.61.6-1.5
K content in liver0.10.10.2-0.2-0.40.40.30.30.30.30.30.3-0.1
Mg content in liver0.40.50.50.60.6-0.7-0.7-0.7-0.7-0.7-0.7-0.70.7
Mn content in liver0.20.30.50.60.6-0.7-0.4-0.5-0.5-0.5-0.5-0.50.4
Na content in liver0.00.00.10.30.1-0.2-0.1-0.1-0.1-0.1-0.1-0.10.3
Rb content in liver0.00.10.1-0.2-0.30.30.20.20.20.20.20.2-0.2
Se content in liver0.60.81.51.20.9-0.9-0.7-0.8-0.8-0.8-0.8-0.80.8
Sr content in liver0.40.40.6-0.6-0.50.60.70.60.60.60.60.6-0.7
Zn content in liver0.50.50.7-0.8-0.80.80.70.70.70.70.70.7-0.8
Bone: minimum diameter0.10.20.30.50.6-0.5-0.3-0.4-0.3-0.3-0.3-0.30.4
Time in familiar zone, hab. session 10.30.40.40.60.5-0.6-0.6-0.6-0.6-0.6-0.6-0.60.6
Time in novel zone, hab. session 10.10.10.2-0.3-0.1-0.10.50.40.40.40.40.5-0.4
Total zone transitions, hab. session 10.10.10.30.30.4-0.5-0.3-0.3-0.3-0.3-0.3-0.30.3
Total locomotion distance, hab. session 10.00.10.1-0.10.00.1-0.3-0.3-0.3-0.3-0.3-0.30.2
Locomotion velocity, hab. session 10.20.30.50.30.4-0.2-0.7-0.6-0.6-0.6-0.6-0.60.6
Time in familiar zone, hab. session 20.10.10.10.40.4-0.3-0.3-0.3-0.3-0.3-0.3-0.30.4
Time in novel zone, hab. session 20.20.20.30.40.5-0.6-0.5-0.5-0.5-0.5-0.5-0.50.3
Total zone transitions, hab. session 20.20.20.3-0.4-0.50.30.60.50.50.60.60.6-0.4
Total locomotion distance, hab. session 20.00.00.1-0.1-0.1-0.0-0.2-0.1-0.1-0.1-0.1-0.10.2
Locomotion velocity, hab. session 20.00.00.1-0.00.0-0.1-0.2-0.2-0.2-0.2-0.2-0.20.3
Novel to familiar place preference ratio0.50.60.8-0.6-0.60.50.90.80.90.80.80.9-0.8
Novelty place preference0.70.81.1-0.8-0.70.61.11.01.01.01.01.0-1.0
Time in novel zone, NPP test0.81.01.2-0.8-0.80.71.11.01.01.01.01.0-1.0
Total zone transitions, NPP test0.00.00.10.10.2-0.30.10.10.10.10.10.1-0.0
Total locomotion distance, NPP test0.71.01.40.81.0-1.2-1.0-1.0-1.0-1.0-1.0-1.01.1
Locomotion velocity, NPP test0.91.31.81.01.2-1.3-1.2-1.1-1.1-1.1-1.1-1.11.2
Intraocular pressure1.01.61.91.21.4-1.4-1.3-1.2-1.2-1.2-1.2-1.21.3
Delta distance traveled before/after self-admin3.13.54.0-2.0-1.91.91.81.81.81.81.81.8-1.9
Delta ambulatory time before/after self-admin1.52.73.2-1.8-1.71.71.61.61.61.61.61.6-1.6
Parametrial fat weight7.016.420.0-4.5-4.14.14.04.04.04.04.04.0-3.7
Pavlov. Cond. lever latency0.00.00.1-0.1-0.00.00.20.20.20.20.20.2-0.3
Pavlov. Cond. magazine entry latency0.00.00.2-0.2-0.40.40.10.10.10.10.10.1-0.0
Pavlov. Cond. change in total contacts0.30.40.60.60.4-0.4-0.6-0.6-0.6-0.6-0.6-0.60.8
Pavlov. Cond. index score0.00.00.10.1-0.00.1-0.2-0.2-0.2-0.2-0.2-0.20.4
Pavlov. Cond. latency score0.00.00.1-0.1-0.20.3-0.1-0.1-0.1-0.1-0.1-0.10.2
Pavlov. Cond. lever contacts0.00.00.10.1-0.00.0-0.2-0.2-0.2-0.2-0.2-0.20.3
Pavlov. Cond. magazine entry number0.10.20.3-0.3-0.20.10.50.40.40.40.40.5-0.5
Pavlov. Cond. intertrial magazine entries0.20.20.30.40.5-0.6-0.4-0.4-0.4-0.4-0.4-0.40.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.20.20.1-0.1-0.4-0.3-0.4-0.4-0.4-0.40.5
Pavlov. Cond. response bias0.00.00.10.1-0.10.1-0.2-0.2-0.2-0.2-0.2-0.20.3
Pavlov. Cond. lever latency3.04.25.3-2.3-2.22.21.92.02.02.02.02.0-1.9
Pavlov. Cond. magazine entry latency0.20.20.30.40.5-0.3-0.5-0.5-0.5-0.5-0.5-0.50.4
Pavlov. Cond. change in total contacts1.12.63.11.81.8-1.7-1.5-1.6-1.6-1.6-1.6-1.51.4
Pavlov. Cond. index score2.13.44.01.92.0-1.9-1.8-1.8-1.8-1.8-1.8-1.81.7
Pavlov. Cond. latency score2.33.84.42.02.1-2.0-1.9-1.9-1.9-1.9-1.9-1.91.8
Pavlov. Cond. lever contacts1.52.33.01.71.7-1.7-1.4-1.4-1.4-1.4-1.4-1.41.4
Pavlov. Cond. magazine entry number0.10.10.2-0.3-0.40.40.20.20.20.20.20.2-0.2
Pavlov. Cond. intertrial magazine entries0.30.70.7-0.7-0.90.90.90.80.80.80.80.9-0.8
Pavlov. Cond. lever-magazine prob. diff.1.72.63.21.71.8-1.7-1.6-1.6-1.6-1.6-1.6-1.61.5
Pavlov. Cond. response bias1.52.02.81.71.6-1.5-1.3-1.4-1.4-1.4-1.4-1.31.3
Time in closed arm before self-admin0.71.11.4-0.9-1.11.01.11.21.21.21.21.1-0.6
Time in closed arm after self-admin1.41.61.91.41.3-1.3-1.2-1.2-1.2-1.2-1.2-1.21.3
Time in open arm before self-admin1.01.21.61.01.3-1.2-1.1-1.2-1.2-1.2-1.1-1.10.6
Time in open arm after self-admin1.01.11.2-1.0-1.01.01.11.11.11.11.11.1-1.1
Bone: periosteal estimation0.41.11.51.01.2-1.2-1.0-1.0-1.0-1.0-1.0-1.00.8
Bone: periosteal perimeter0.30.70.90.90.9-0.8-0.8-0.8-0.8-0.8-0.8-0.80.6
Bone: post-yield work0.20.30.8-0.5-0.60.90.50.50.50.50.50.5-0.4
Progressive ratio test 1 active lever presses0.50.91.21.10.9-0.8-1.1-0.9-0.9-0.9-1.0-1.01.1
Progressive ratio test 1 breakpoint0.61.01.31.20.9-0.9-1.1-1.0-1.0-1.0-1.0-1.01.1
Progressive ratio test 1 inactive lever presses1.33.44.22.01.9-1.8-1.8-1.8-1.8-1.8-1.8-1.81.8
Progressive ratio test 2 active lever presses0.40.50.80.90.7-0.7-0.7-0.7-0.7-0.7-0.7-0.70.8
Progressive ratio test 2 breakpoint0.30.40.70.80.6-0.6-0.7-0.6-0.6-0.6-0.6-0.60.7
Progressive ratio test 2 inactive lever presses0.10.20.40.70.4-0.4-0.5-0.4-0.4-0.4-0.4-0.40.4
Incentive Sensitization - Responses0.00.00.1-0.3-0.20.20.20.20.20.20.20.2-0.1
Incentive Sensitization - Breakpoint0.00.10.1-0.4-0.30.30.20.20.20.20.20.2-0.2
Sum of active levers in priming session hrs 5-61.91.81.9-1.4-1.41.41.31.31.31.31.31.3-1.2
Progressive ratio0.10.20.3-0.5-0.40.20.40.40.40.40.40.4-0.3
Food seeking constrained by brief footshock0.20.20.5-0.4-0.50.70.30.40.40.40.40.4-0.6
Seeking ratio, punishment vs. effort0.10.30.50.70.5-0.3-0.5-0.5-0.5-0.5-0.5-0.50.3
Retroperitoneal fat weight0.52.12.9-1.7-1.61.71.31.41.41.41.41.3-1.3
Reaction time number correct0.31.11.5-0.9-0.80.51.21.11.11.11.11.1-1.2
Reaction time mean minus median0.00.30.4-0.5-0.40.30.60.60.60.60.60.6-0.5
Reaction time mean minus median AUC0.32.02.2-1.4-1.41.21.51.51.51.51.51.5-1.3
Reaction time num false alarms4.57.78.32.82.7-2.5-2.9-2.8-2.9-2.8-2.8-2.82.6
Reaction time num false alarms AUC3.47.78.22.82.7-2.5-2.9-2.9-2.9-2.9-2.8-2.82.6
Reaction time trials correct on left0.31.11.5-0.9-0.80.51.21.11.11.11.11.1-1.2
Reaction time trials on left0.31.11.5-0.9-0.80.61.21.11.11.11.11.1-1.2
Reaction time mean0.51.21.3-1.1-0.90.91.11.11.11.11.11.1-1.1
Reaction time mean AUC0.30.81.0-0.9-0.70.71.01.01.01.01.01.0-0.9
Median of all reaction times0.50.81.0-1.0-0.70.71.01.01.01.01.01.0-0.9
Reaction time omissions0.91.51.9-1.2-1.31.41.21.21.21.21.21.2-1.0
Reaction time false alarm rate5.77.98.72.82.6-2.4-3.0-2.9-2.9-2.9-2.9-2.92.8
Reaction time premature initiation rate0.00.10.10.1-0.2-0.00.30.30.30.30.30.3-0.1
Reaction time premature initiations0.10.30.5-0.2-0.40.10.70.60.60.60.60.6-0.5
Std. dev. reaction times0.31.01.2-1.0-0.90.91.11.11.11.11.11.1-1.0
Reaction time trials completed0.31.11.5-0.9-0.80.61.21.11.11.11.11.1-1.2
Reaction time trials AUC0.30.91.2-0.8-0.70.51.11.01.01.01.01.0-1.1
Run reversals in cocaine runway, females0.10.10.5-0.5-0.10.10.30.20.20.20.20.2-0.7
Run reversals in cocaine runway, males0.00.00.10.0-0.20.10.20.20.20.20.20.20.4
Latency to leave start box in cocaine runway0.00.00.1-0.10.2-0.3-0.1-0.2-0.2-0.2-0.2-0.2-0.2
Latency to leave start box in cocaine runway, F0.00.00.1-0.3-0.10.00.20.10.10.10.10.1-0.4
Latency to leave start box in cocaine runway, M0.00.00.0-0.10.2-0.2-0.1-0.1-0.1-0.1-0.1-0.1-0.1
Std. dev. time between licks in bursts0.00.00.1-0.30.2-0.10.10.10.10.10.10.1-0.1
Total sessions with >9 infusions0.10.10.1-0.3-0.30.40.30.30.30.30.30.2-0.0
Short access day 1 total inactive lever presses1.42.83.5-1.5-1.61.71.91.71.71.71.71.7-1.5
Short access day 10 total inactive lever presses0.00.10.30.50.2-0.3-0.1-0.2-0.2-0.2-0.2-0.20.3
Short access day 1 total infusions0.10.20.3-0.1-0.40.40.50.50.50.50.50.5-0.2
Short access day 10 total infusions0.00.10.2-0.1-0.30.40.40.30.30.30.30.3-0.1
Short access total infusions0.00.00.20.40.1-0.0-0.0-0.0-0.0-0.0-0.0-0.10.4
Short access day 1 locomotion0.10.10.20.40.3-0.3-0.3-0.3-0.3-0.3-0.3-0.30.4
Short access day 10 total locomotion0.20.91.11.01.0-1.0-0.9-0.9-0.9-0.9-0.9-0.90.9
Short access total locomotion0.60.91.11.11.0-1.0-0.9-0.9-0.9-0.9-1.0-1.01.0
One hour access (0.3 mA shock)0.20.20.50.30.3-0.2-0.7-0.4-0.5-0.5-0.5-0.50.6
Compulsive drug intake0.71.01.1-1.0-1.01.10.91.01.01.01.01.0-0.8
One hour access (shock baseline)0.10.30.40.60.5-0.4-0.7-0.6-0.6-0.6-0.6-0.60.7
Social response proportion2.02.63.6-1.8-1.71.91.51.51.51.51.51.5-1.6
Social responses1.82.33.2-1.8-1.61.41.51.51.51.51.51.5-1.4
Social time1.21.92.6-1.5-1.51.61.31.41.31.31.31.3-1.1
Soleus weight2.36.97.4-2.7-2.72.72.62.62.62.62.62.6-2.4
Bone: stiffness1.42.52.8-1.3-1.51.51.71.61.61.61.61.6-1.6
Tibialis anterior weight2.89.510.4-3.2-3.13.03.13.13.13.13.13.1-2.8
Time to tail flick, vehicle, before self-admin0.00.00.00.0-0.0-0.00.00.00.00.00.00.00.1
Time to tail flick, vehicle, after self-admin0.30.60.80.80.6-0.6-0.8-0.7-0.8-0.8-0.8-0.80.9
Time to tail flick, test, before self-admin0.00.00.0-0.1-0.10.10.10.10.10.10.10.1-0.1
Time to tail flick, test, after self-admin0.10.10.10.40.3-0.3-0.2-0.3-0.3-0.3-0.2-0.20.1
Delta time to tail flick, vehicle, before/after SA0.10.10.10.20.3-0.3-0.4-0.4-0.4-0.4-0.4-0.40.3
Delta time to tail flick, test, before/after SA0.30.40.60.80.7-0.7-0.6-0.6-0.6-0.6-0.6-0.60.6
Tibia length0.00.10.2-0.0-0.20.5-0.3-0.3-0.3-0.3-0.3-0.30.1
Ambulatory time before self-admin1.02.93.41.81.6-1.7-1.7-1.7-1.7-1.7-1.7-1.71.8
Ambulatory time after self-admin0.00.00.0-0.1-0.00.1-0.0-0.0-0.0-0.0-0.0-0.00.2
Bone: tissue strength1.51.62.01.41.1-0.8-1.3-1.4-1.4-1.4-1.4-1.41.2
Total heroin consumption5.26.18.0-2.8-2.42.52.42.52.42.42.42.5-2.4
Bone: trabecular number2.65.05.7-2.2-2.32.42.32.22.22.22.22.2-2.1
Bone: trabecular spacing0.30.40.50.60.6-0.5-0.7-0.6-0.6-0.6-0.6-0.60.6
Bone: trabecular thickness0.00.00.00.20.1-0.1-0.0-0.1-0.1-0.1-0.1-0.1-0.0
Bone: trabecular tissue density1.22.12.71.61.6-1.6-1.4-1.4-1.4-1.4-1.4-1.41.3
Water consumed over 24 hours0.00.00.10.10.2-0.3-0.1-0.1-0.1-0.1-0.1-0.1-0.1
Number of responses in last shaping day0.71.01.11.00.9-0.9-0.9-1.0-1.0-1.0-1.0-1.01.0