Hub : Genes

LOC120095265

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc mRNA stability LOC120095265 0.03 0.03 1.5e-04 0.02 0.02 0.03 0.02 3.2e-04 2.0e-04 1.4e-05 2.5e-04
2 OFC gene expression LOC120095265 0.39 0.25 2.4e-07 0.21 0.27 0.2 0.28 1.1e-05 3.1e-07 1.5e-05 3.0e-07
3 Brain mRNA stability LOC120095265 0.09 0.08 1.4e-07 0.06 0.08 0.08 0.08 2.2e-06 8.5e-08 7.9e-08 7.8e-08
4 Adipose gene expression LOC120095265 0.19 0.11 0.0e+00 0.18 0.18 0.17 0.17 1.0e-19 1.9e-19 1.6e-18 1.2e-18
5 pVTA gene expression LOC120095265 0.13 0.12 5.8e-10 0.1 0.12 0.11 0.12 8.6e-09 6.7e-10 2.0e-09 1.2e-09
6 IL gene expression LOC120095265 0.41 0.25 2.9e-08 0.26 0.32 0.29 0.3 6.7e-07 1.9e-08 1.4e-07 5.1e-08
7 Brain gene expression LOC120095265 0.11 0.1 5.5e-09 0.08 0.09 0.09 0.09 2.9e-08 4.1e-09 4.5e-09 6.6e-09
8 PL gene expression LOC120095265 0.16 0.14 8.3e-16 0.09 0.15 0.12 0.12 2.0e-10 7.0e-16 2.5e-13 6.5e-13
9 NAcc gene expression LOC120095265 0.19 0.16 0.0e+00 0.16 0.17 0.16 0.17 1.0e-23 1.9e-25 5.5e-24 4.9e-25
10 IC gene expression LOC120095265 0.2 0.16 7.2e-07 0.16 0.13 0.17 0.13 4.5e-07 5.1e-06 1.8e-07 5.9e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density2.23.74.41.82.12.1-2.01.91.91.91.91.91.8
Area under the delay curve2.52.93.3-1.5-1.8-1.81.7-1.8-1.8-1.8-1.8-1.8-1.5
BMI with tail1.55.36.02.52.22.2-2.32.42.42.42.42.32.2
BMI without tail2.26.67.22.72.62.6-2.62.62.62.62.62.52.5
Body weight2.611.513.63.73.63.6-3.33.33.33.33.33.33.4
Weight adjusted by age0.20.20.40.60.50.4-0.50.50.50.50.50.50.2
Bone surface1.52.72.91.51.71.7-1.71.71.71.71.71.71.5
Bone volume1.42.53.21.51.81.8-1.61.51.51.51.51.51.5
Breakpoint value in progressive ratio session0.91.11.41.21.01.0-1.01.11.01.01.01.11.0
Number of licking bursts0.20.30.5-0.5-0.7-0.70.5-0.5-0.5-0.5-0.5-0.5-0.6
Context. condit. distance diff. score0.60.81.10.81.11.1-0.80.80.80.80.80.80.8
Locomotion velocity, session 11.82.02.41.40.90.9-1.51.51.51.51.51.51.5
Locomotion distance, session 10.20.20.40.5-0.1-0.1-0.50.50.50.50.50.60.6
Locomotion velocity, session 20.10.10.10.3-0.1-0.1-0.20.30.30.30.30.30.3
Locomotion distance, session 20.91.31.61.00.70.6-1.31.31.31.31.31.31.0
Locomotion velocity, session 32.83.23.5-1.7-1.6-1.61.9-1.8-1.8-1.8-1.8-1.9-1.9
Locomotion distance, session 30.40.40.5-0.6-0.5-0.50.7-0.7-0.7-0.7-0.7-0.7-0.6
Stereotopy head waving bouts, day 30.00.00.0-0.1-0.1-0.1-0.20.10.10.10.10.20.0
Stereotopy head waving duration, day 30.40.50.8-0.9-0.9-0.90.5-0.6-0.6-0.6-0.6-0.6-0.7
Locomotion velocity, session 70.50.60.80.90.80.8-0.70.70.70.70.70.70.7
Locomotion distance, session 70.60.80.90.90.80.8-0.80.90.90.90.90.90.9
Stereotopy head waving bouts, day 70.50.60.70.70.90.9-0.80.80.80.80.80.80.5
Stereotopy head waving duration, day 70.20.30.40.40.50.5-0.60.60.60.60.60.60.4
Locomotion velocity, session 80.00.00.10.10.30.3-0.10.10.10.10.10.10.1
Locomotion distance, session 80.71.01.20.90.90.9-1.11.11.11.11.11.10.9
Degree of sensitization distance3.43.53.71.91.71.7-1.91.91.91.91.91.91.8
Degree of sensitization stereotypy0.60.70.90.80.90.9-0.80.80.80.80.80.80.6
Conditioned locomotion1.11.31.5-1.1-1.0-0.91.2-1.2-1.2-1.2-1.2-1.2-1.2
Cocaine response after cond. corrected1.61.92.41.51.21.2-1.41.51.41.41.41.41.2
Cocaine response after cond. not corrected2.22.53.01.71.41.3-1.61.71.71.71.71.61.4
Cocaine response before conditioning0.20.20.30.30.20.2-0.50.50.50.50.50.50.5
Saline control response0.00.00.00.0-0.1-0.10.1-0.0-0.0-0.0-0.0-0.0-0.1
Bone: connectivity density3.75.86.42.32.52.5-2.52.42.42.42.42.42.2
Bone: cortical apparent density0.30.40.4-0.6-0.5-0.50.7-0.6-0.6-0.6-0.6-0.6-0.7
Bone: cortical area1.32.02.2-1.5-1.3-1.21.5-1.5-1.5-1.5-1.5-1.5-1.3
Bone: cortical porosity0.20.30.30.40.60.6-0.50.50.50.50.50.50.5
Bone: cortical porosity0.10.10.10.20.30.3-0.30.30.30.30.30.30.3
Bone: cortical thickness2.33.74.2-2.0-1.6-1.62.0-2.0-2.0-2.0-2.0-2.1-1.9
Bone: cortical thickness0.00.00.0-0.1-0.1-0.10.1-0.1-0.1-0.1-0.1-0.1-0.1
Bone: cortical tissue density0.10.20.2-0.4-0.3-0.30.5-0.4-0.4-0.4-0.4-0.4-0.5
Condit. Reinf. active minus inactive responses0.60.60.7-0.8-0.6-0.60.8-0.8-0.8-0.8-0.8-0.8-0.9
Condit. Reinf. active-inactive response ratio0.10.20.2-0.4-0.2-0.20.4-0.4-0.4-0.4-0.4-0.4-0.4
Condit. Reinf. active responses0.00.00.0-0.0-0.1-0.10.1-0.1-0.1-0.1-0.1-0.1-0.2
Condit. Reinf. inactive responses0.30.30.40.70.30.2-0.60.70.60.60.60.60.5
Incentive salience index mean0.20.30.4-0.5-0.3-0.30.6-0.6-0.6-0.6-0.6-0.6-0.7
Condit. Reinf. lever presses0.10.20.50.50.70.7-0.30.30.30.30.30.30.1
Condit. Reinf. active minus inactive responses0.20.20.4-0.6-0.5-0.50.5-0.5-0.5-0.4-0.4-0.4-0.5
Condit. Reinf. active-inactive response ratio0.50.50.6-0.8-0.6-0.50.8-0.7-0.7-0.7-0.7-0.7-0.8
Condit. Reinf. active responses0.10.10.2-0.4-0.3-0.30.3-0.3-0.3-0.3-0.3-0.3-0.3
Condit. Reinf. inactive responses0.10.10.20.30.50.5-0.40.30.30.30.30.30.4
Condit. Reinf. lever presses2.63.64.2-2.0-1.9-1.91.9-1.9-1.9-1.9-1.9-1.8-1.8
Condit. Reinf. lever reinforcers received0.30.40.6-0.7-0.5-0.50.6-0.6-0.6-0.6-0.6-0.6-0.6
Conditioned reinforcement - actives0.20.30.40.60.60.6-0.50.50.50.50.50.50.3
Conditioned reinforcement - inactives0.00.10.20.20.10.1-0.30.20.30.30.30.30.4
Conditioned locomotion0.10.10.20.30.50.5-0.40.30.30.30.30.30.2
Patch foraging indifference point 0 sec0.30.50.5-0.6-0.7-0.70.7-0.7-0.7-0.7-0.7-0.7-0.6
Patch foraging indifference point AUC2.13.13.8-1.6-1.9-1.91.8-1.6-1.7-1.7-1.7-1.7-1.9
Delay disc. indifference point, 0s delay1.21.31.5-1.2-1.2-1.21.1-1.1-1.1-1.1-1.1-1.1-1.0
Delay disc. indifference point, 16s delay2.22.43.0-1.3-1.7-1.71.5-1.6-1.6-1.6-1.6-1.6-1.4
Delay disc. indifference point, 2s delay2.62.93.2-1.6-1.7-1.71.7-1.8-1.8-1.8-1.8-1.8-1.4
Delay disc. indifference point, 24s delay0.70.71.01.00.90.9-0.80.80.80.80.80.80.9
Delay disc. indifference point, 4s delay0.30.30.6-0.5-0.8-0.80.6-0.6-0.6-0.6-0.6-0.6-0.1
Delay disc. indifference point, 8s delay1.21.41.7-1.0-1.0-1.01.3-1.3-1.3-1.3-1.3-1.3-1.3
Indifference point function ln k0.61.01.50.91.21.2-1.00.90.90.90.90.91.1
Indifference point function log k0.61.01.50.91.21.2-1.00.90.90.90.90.91.1
Patch foraging total patch changes 0 sec0.20.30.4-0.5-0.6-0.60.6-0.6-0.6-0.6-0.6-0.6-0.5
Patch foraging total patch changes 12 sec0.20.30.4-0.4-0.6-0.60.5-0.5-0.5-0.5-0.5-0.5-0.5
Patch foraging total patch changes 18 sec1.31.92.3-1.3-1.5-1.51.4-1.4-1.4-1.4-1.4-1.4-1.3
Patch foraging total patch changes 24 sec1.83.14.5-1.7-2.1-2.11.7-1.7-1.7-1.7-1.7-1.7-1.7
Patch foraging total patch changes 6 sec3.45.25.5-2.3-2.3-2.32.3-2.2-2.2-2.2-2.2-2.3-2.3
Patch foraging time to switch 0 sec1.12.22.41.41.41.4-1.51.51.51.51.51.51.4
Patch foraging water rate 0 sec1.53.24.0-1.8-2.0-2.01.7-1.8-1.7-1.7-1.7-1.7-1.6
Patch foraging water rate 12 sec0.20.40.50.70.70.7-0.60.60.60.60.60.60.7
Patch foraging water rate 18 sec0.30.50.70.50.80.8-0.80.70.70.70.70.70.7
Patch foraging water rate 24 sec0.20.30.3-0.6-0.6-0.50.5-0.6-0.6-0.6-0.6-0.5-0.3
Patch foraging water rate 6 sec0.91.31.5-1.1-1.2-1.21.1-1.2-1.2-1.2-1.2-1.2-1.0
Seeking ratio, delayed vs. immediate footshock2.12.63.7-1.8-1.3-1.31.6-1.6-1.6-1.6-1.6-1.6-1.9
Distance traveled before self-admin3.64.75.5-2.3-2.1-2.12.2-2.1-2.1-2.1-2.1-2.1-2.3
Distance traveled after self-admin0.10.10.4-0.3-0.2-0.20.4-0.3-0.3-0.3-0.3-0.3-0.6
Extensor digitorum longus weight0.72.62.81.71.51.5-1.71.71.71.71.71.71.4
Bone: elastic displacement2.93.43.5-1.7-1.8-1.81.9-1.9-1.9-1.9-1.9-1.9-1.7
Bone: elastic work7.49.610.6-3.1-2.8-2.83.2-3.3-3.3-3.3-3.3-3.3-2.8
Bone: endosteal estimation0.10.10.4-0.3-0.7-0.70.2-0.3-0.3-0.3-0.3-0.3-0.1
Bone: endosteal perimeter0.00.00.1-0.2-0.3-0.30.0-0.1-0.1-0.1-0.1-0.10.0
Epididymis fat weight7.626.027.75.35.25.2-5.15.15.15.15.15.04.9
Delta time in closed arm before/after self-admin2.72.52.7-1.5-1.5-1.51.6-1.6-1.6-1.6-1.6-1.6-1.4
Delta time in open arm before/after self-admin5.25.15.42.12.32.3-2.32.32.32.32.32.31.9
Diff in mean of infusions in LGA sessions0.50.60.70.70.80.8-0.80.80.80.80.80.80.8
Delay discount exponential model param1.71.92.21.21.51.5-1.41.41.41.41.41.41.1
Extinction: sum of active levers before priming1.11.21.50.90.90.9-1.21.11.11.11.11.11.2
Active lever presses in extinction session 60.60.60.70.80.70.7-0.80.80.80.80.80.80.8
Bone: final force0.30.50.6-0.7-0.4-0.40.8-0.8-0.8-0.8-0.8-0.8-0.6
Bone: final moment0.40.60.8-0.9-0.6-0.60.8-0.9-0.9-0.9-0.9-0.9-0.7
Food consumed during 24 hour testing period0.10.10.2-0.2-0.5-0.50.3-0.4-0.4-0.4-0.4-0.4-0.1
Glucose1.52.32.6-1.5-1.3-1.31.6-1.6-1.6-1.6-1.6-1.6-1.6
Heart weight2.03.03.41.91.71.7-1.81.71.71.71.71.71.8
Delay discount hyperbolic model param2.12.42.81.31.71.7-1.61.61.61.61.61.61.2
Intermittent access intake day 1-15 change0.00.00.0-0.00.00.0-0.10.10.10.10.10.1-0.1
Intermittent access intake escalation0.00.00.10.10.20.2-0.30.20.20.20.20.20.0
Intermittent access intake escalation 20.30.30.4-0.6-0.6-0.60.5-0.5-0.5-0.5-0.5-0.5-0.7
Intermitt. access day 1 inactive lever presses0.10.30.7-0.8-0.6-0.60.3-0.5-0.5-0.5-0.5-0.5-0.5
Intermitt. access day 15 inactive lever presses0.40.71.3-1.1-0.8-0.80.8-0.8-0.8-0.8-0.8-0.8-0.8
Intermitt. access escalation Index0.71.01.91.41.01.0-1.11.01.01.01.00.90.9
Intermittent access day 1 total infusions0.00.10.10.30.30.3-0.10.20.20.20.20.20.2
Intermittent access day 15 total infusions0.40.60.70.60.80.8-0.80.80.80.80.80.80.6
Intermittent access terminal intake (last 3 days)0.60.81.00.81.01.0-0.80.90.90.90.90.90.7
Intermittent access total infusions0.10.10.30.10.50.5-0.30.30.30.30.30.30.0
Intermittent access day 1 locomotion0.00.00.0-0.10.10.10.1-0.0-0.0-0.0-0.0-0.0-0.1
Intermittent access day 15 total locomotion0.20.30.40.50.60.6-0.50.50.50.50.50.50.4
Intermittent access total locomotion0.30.40.70.50.80.8-0.50.60.60.60.60.60.4
Intermittent access standard deviation0.00.10.2-0.4-0.1-0.20.2-0.2-0.2-0.2-0.2-0.2-0.3
Left kidney weight0.10.40.90.80.90.9-0.60.50.50.50.50.50.7
Right kidney weight0.20.81.60.91.21.3-0.70.70.70.70.70.70.8
Cocaine induced anxiety0.10.20.2-0.4-0.4-0.40.5-0.5-0.5-0.5-0.5-0.4-0.3
Post-drug Anxiety0.20.30.30.40.60.6-0.50.50.50.50.50.50.4
Baseline Anxiety0.50.60.60.60.80.7-0.80.80.80.80.80.80.6
Tail length0.62.43.81.81.92.0-1.41.41.41.41.41.31.5
Length with tail0.73.25.22.12.22.3-1.61.51.51.51.51.51.8
Length without tail0.31.01.81.31.31.3-0.80.90.80.90.90.81.0
Times rat made contact with spout0.00.00.10.30.10.1-0.00.10.10.10.10.10.1
Lifetime Intake0.20.20.30.20.60.5-0.40.50.40.40.40.40.2
Liver weight, left4.98.110.13.03.23.2-2.72.82.72.72.82.72.6
Liver weight, right4.37.69.53.13.13.1-2.62.62.62.62.62.62.6
Locomotor activity0.10.20.7-0.4-0.8-0.80.3-0.3-0.3-0.3-0.3-0.3-0.2
Locomotor testing distance0.20.30.8-0.4-0.9-0.90.4-0.4-0.4-0.4-0.4-0.4-0.6
Locomotor testing rearing0.10.10.5-0.2-0.7-0.70.1-0.1-0.1-0.1-0.1-0.1-0.2
Locomotion in novel chamber2.93.84.7-2.0-1.8-1.81.9-1.9-1.9-1.9-1.9-2.0-2.2
Locomotion in novel chamber post-restriction0.00.00.4-0.20.1-0.0-0.00.10.10.10.10.0-0.6
Fecal boli incidents, locomotor time 11.82.63.51.71.91.9-1.61.61.61.61.61.61.4
Change in fecal boli incidents, locomotor task0.30.30.4-0.6-0.6-0.60.6-0.6-0.6-0.6-0.6-0.6-0.3
Time >=10cm from walls, locomotor time 10.00.00.00.10.10.1-0.20.10.20.20.10.10.1
Bouts of movement, locomotor time 10.60.60.9-0.8-1.0-1.00.8-0.8-0.8-0.8-0.7-0.7-0.7
Total resting periods, locomotor time 10.10.10.3-0.3-0.5-0.50.3-0.3-0.3-0.3-0.3-0.3-0.3
Rest time, locomotor task time 10.20.30.40.40.40.3-0.60.60.60.60.60.60.6
Distance moved, locomotor task time 10.50.81.1-0.9-1.0-1.00.8-0.8-0.8-0.8-0.8-0.8-0.8
Vertical activity count, locomotor time 10.20.40.4-0.7-0.6-0.60.6-0.6-0.6-0.6-0.6-0.6-0.6
Time >=10cm from walls, locomotor time 20.60.91.20.80.90.9-1.00.90.90.90.90.91.1
Bouts of movement, locomotor time 20.20.40.7-0.6-0.8-0.80.6-0.6-0.6-0.6-0.6-0.6-0.2
Total resting periods, locomotor time 20.00.10.2-0.2-0.4-0.40.2-0.2-0.2-0.2-0.2-0.20.1
Rest time, locomotor task time 20.10.10.20.30.40.4-0.40.40.40.40.40.40.4
Distance moved, locomotor task time 20.80.91.1-1.0-1.0-1.10.9-0.9-0.9-0.9-0.9-0.9-1.0
Vertical activity count, locomotor time 21.01.41.6-1.2-1.3-1.31.2-1.2-1.2-1.2-1.2-1.2-1.1
Light reinforcement 10.00.00.2-0.1-0.0-0.00.2-0.2-0.2-0.2-0.2-0.2-0.4
Light reinforcement 20.40.60.8-0.7-0.9-0.90.7-0.7-0.8-0.8-0.8-0.8-0.7
Bone: marrow area0.10.20.5-0.3-0.7-0.70.2-0.3-0.3-0.3-0.3-0.3-0.1
Bone: maximum diameter0.40.80.9-1.0-1.0-0.90.9-0.9-0.9-0.9-0.9-0.9-0.8
Bone: maximum force0.51.01.1-1.0-0.8-0.71.0-1.1-1.1-1.1-1.1-1.1-0.9
Bone: maximum moment0.71.31.5-1.2-1.0-1.01.1-1.2-1.2-1.2-1.2-1.2-1.0
Mean time between licks in bursts0.41.11.41.21.11.1-1.01.01.01.01.01.00.9
Mean num. licks in bursts0.30.50.80.90.80.8-0.70.70.70.70.70.60.7
Cd content in liver0.80.91.4-0.8-1.2-1.21.0-0.9-0.9-0.9-0.9-0.9-0.8
Co content in liver0.30.30.5-0.4-0.6-0.70.6-0.5-0.5-0.5-0.5-0.5-0.7
Cu content in liver1.31.51.8-1.2-1.3-1.31.2-1.2-1.2-1.2-1.2-1.2-1.1
Fe content in liver1.92.42.51.51.51.5-1.61.61.61.61.61.61.5
K content in liver0.10.10.10.20.40.4-0.30.30.30.30.30.30.1
Mg content in liver0.50.50.5-0.6-0.7-0.60.7-0.7-0.7-0.7-0.7-0.7-0.7
Mn content in liver0.20.30.5-0.6-0.7-0.70.4-0.5-0.5-0.5-0.5-0.5-0.4
Na content in liver0.00.00.1-0.3-0.2-0.20.1-0.1-0.1-0.1-0.1-0.1-0.3
Rb content in liver0.00.10.10.20.30.3-0.20.20.20.20.20.20.2
Se content in liver0.60.81.5-1.2-0.9-0.90.7-0.8-0.8-0.8-0.8-0.8-0.8
Sr content in liver0.40.40.60.60.60.6-0.70.60.60.60.60.60.7
Zn content in liver0.50.50.60.80.80.8-0.70.70.70.70.70.70.8
Bone: minimum diameter0.10.20.3-0.5-0.5-0.50.3-0.4-0.3-0.3-0.3-0.3-0.4
Time in familiar zone, hab. session 10.40.40.4-0.6-0.6-0.60.6-0.6-0.6-0.6-0.6-0.6-0.6
Time in novel zone, hab. session 10.10.10.20.3-0.1-0.1-0.50.40.40.40.40.50.4
Total zone transitions, hab. session 10.10.10.3-0.3-0.5-0.50.3-0.3-0.3-0.3-0.3-0.3-0.3
Total locomotion distance, hab. session 10.00.10.10.10.10.10.3-0.3-0.3-0.3-0.3-0.3-0.2
Locomotion velocity, hab. session 10.20.30.5-0.3-0.2-0.20.7-0.6-0.6-0.6-0.6-0.6-0.6
Time in familiar zone, hab. session 20.10.10.1-0.3-0.3-0.30.3-0.3-0.3-0.3-0.3-0.3-0.4
Time in novel zone, hab. session 20.20.20.3-0.4-0.6-0.60.5-0.5-0.5-0.5-0.5-0.5-0.3
Total zone transitions, hab. session 20.20.20.30.40.30.3-0.60.50.50.60.60.60.4
Total locomotion distance, hab. session 20.00.00.10.1-0.0-0.00.2-0.1-0.1-0.1-0.1-0.1-0.2
Locomotion velocity, hab. session 20.00.00.10.0-0.1-0.10.2-0.2-0.2-0.2-0.2-0.2-0.3
Novel to familiar place preference ratio0.50.60.80.70.50.4-0.90.80.90.80.80.90.8
Novelty place preference0.80.81.10.80.60.6-1.11.01.01.01.01.01.0
Time in novel zone, NPP test0.90.91.20.80.70.7-1.11.01.01.01.01.01.0
Total zone transitions, NPP test0.00.00.1-0.1-0.3-0.4-0.10.10.10.10.10.10.0
Total locomotion distance, NPP test0.81.01.4-0.8-1.2-1.21.0-1.0-1.0-1.0-1.0-1.0-1.1
Locomotion velocity, NPP test0.91.31.9-1.0-1.3-1.41.2-1.1-1.1-1.1-1.1-1.1-1.2
Intraocular pressure1.11.62.0-1.2-1.4-1.41.3-1.2-1.2-1.2-1.2-1.2-1.3
Delta distance traveled before/after self-admin3.33.54.02.01.91.9-1.81.81.81.81.81.81.9
Delta ambulatory time before/after self-admin2.22.73.21.81.71.7-1.61.61.61.61.61.61.6
Parametrial fat weight6.916.319.94.54.14.1-4.04.04.04.04.04.03.7
Pavlov. Cond. lever latency0.00.00.10.10.00.0-0.20.20.20.20.20.20.3
Pavlov. Cond. magazine entry latency0.00.00.20.20.40.4-0.10.10.10.10.10.10.0
Pavlov. Cond. change in total contacts0.30.40.6-0.6-0.4-0.40.6-0.6-0.6-0.6-0.6-0.6-0.8
Pavlov. Cond. index score0.00.00.1-0.10.10.10.2-0.2-0.2-0.2-0.2-0.2-0.4
Pavlov. Cond. latency score0.00.00.10.10.30.30.1-0.1-0.1-0.1-0.1-0.1-0.2
Pavlov. Cond. lever contacts0.00.00.1-0.10.00.00.2-0.2-0.2-0.2-0.2-0.2-0.3
Pavlov. Cond. magazine entry number0.10.20.30.30.10.1-0.50.40.40.40.40.50.5
Pavlov. Cond. intertrial magazine entries0.20.20.3-0.4-0.6-0.60.4-0.4-0.4-0.4-0.4-0.4-0.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.2-0.2-0.1-0.10.4-0.3-0.4-0.4-0.4-0.4-0.5
Pavlov. Cond. response bias0.00.00.1-0.10.10.10.2-0.2-0.2-0.2-0.2-0.2-0.3
Pavlov. Cond. lever latency3.14.25.22.32.22.2-1.92.02.02.02.02.01.9
Pavlov. Cond. magazine entry latency0.20.20.3-0.4-0.3-0.30.5-0.5-0.5-0.5-0.5-0.5-0.4
Pavlov. Cond. change in total contacts1.62.63.1-1.8-1.7-1.71.5-1.6-1.6-1.6-1.6-1.5-1.4
Pavlov. Cond. index score2.53.33.7-1.9-1.9-1.91.8-1.8-1.8-1.8-1.8-1.8-1.7
Pavlov. Cond. latency score2.83.74.1-2.0-2.0-2.01.9-1.9-1.9-1.9-1.9-1.9-1.8
Pavlov. Cond. lever contacts1.62.33.0-1.7-1.7-1.71.4-1.4-1.4-1.4-1.4-1.4-1.4
Pavlov. Cond. magazine entry number0.00.10.10.30.40.4-0.20.20.20.20.20.20.2
Pavlov. Cond. intertrial magazine entries0.40.70.70.70.90.9-0.90.80.80.80.80.90.8
Pavlov. Cond. lever-magazine prob. diff.1.92.63.0-1.7-1.7-1.71.6-1.6-1.6-1.6-1.6-1.6-1.5
Pavlov. Cond. response bias1.42.02.7-1.7-1.5-1.51.3-1.4-1.4-1.4-1.4-1.3-1.3
Time in closed arm before self-admin0.91.11.40.91.01.0-1.11.21.21.21.21.10.6
Time in closed arm after self-admin1.51.61.9-1.4-1.3-1.31.2-1.2-1.2-1.2-1.2-1.2-1.3
Time in open arm before self-admin1.11.21.5-1.0-1.2-1.21.1-1.2-1.2-1.2-1.1-1.1-0.6
Time in open arm after self-admin1.01.11.21.01.01.0-1.11.11.11.11.11.11.1
Bone: periosteal estimation0.51.11.4-1.0-1.2-1.21.0-1.0-1.0-1.0-1.0-1.0-0.8
Bone: periosteal perimeter0.40.70.8-0.9-0.8-0.80.8-0.8-0.8-0.8-0.8-0.8-0.6
Bone: post-yield work0.20.30.80.50.90.9-0.50.50.50.50.50.50.4
Progressive ratio test 1 active lever presses0.80.91.2-1.1-0.8-0.81.1-0.9-0.9-0.9-1.0-1.0-1.1
Progressive ratio test 1 breakpoint0.81.01.3-1.2-0.9-0.91.1-1.0-1.0-1.0-1.0-1.0-1.1
Progressive ratio test 1 inactive lever presses2.33.44.2-2.0-1.8-1.81.8-1.8-1.8-1.8-1.8-1.8-1.8
Progressive ratio test 2 active lever presses0.40.50.8-0.9-0.7-0.70.7-0.7-0.7-0.7-0.7-0.7-0.8
Progressive ratio test 2 breakpoint0.40.40.7-0.8-0.6-0.60.7-0.6-0.6-0.6-0.6-0.6-0.7
Progressive ratio test 2 inactive lever presses0.10.20.4-0.7-0.4-0.40.5-0.4-0.4-0.4-0.4-0.4-0.4
Incentive Sensitization - Responses0.00.00.10.30.20.2-0.20.20.20.20.20.20.1
Incentive Sensitization - Breakpoint0.00.10.10.40.20.3-0.20.20.20.20.20.20.2
Sum of active levers in priming session hrs 5-61.91.81.91.41.41.4-1.31.31.31.31.31.31.2
Progressive ratio0.10.20.30.50.20.2-0.40.40.40.40.40.40.3
Food seeking constrained by brief footshock0.20.20.50.40.70.7-0.30.40.40.40.40.40.6
Seeking ratio, punishment vs. effort0.20.20.4-0.7-0.3-0.30.5-0.5-0.5-0.5-0.5-0.5-0.3
Retroperitoneal fat weight0.52.12.91.71.71.7-1.31.41.41.41.41.31.3
Reaction time number correct0.51.01.50.90.50.5-1.21.11.11.11.11.11.2
Reaction time mean minus median0.10.30.40.50.30.3-0.60.60.60.60.60.60.5
Reaction time mean minus median AUC0.82.02.21.41.21.2-1.51.51.51.51.51.51.3
Reaction time num false alarms5.47.68.3-2.8-2.5-2.52.9-2.8-2.9-2.8-2.8-2.8-2.6
Reaction time num false alarms AUC4.97.68.2-2.9-2.5-2.52.9-2.9-2.9-2.9-2.8-2.8-2.6
Reaction time trials correct on left0.51.01.50.90.50.5-1.21.11.11.11.11.11.2
Reaction time trials on left0.61.01.50.90.60.5-1.21.11.11.11.11.11.2
Reaction time mean0.71.21.31.10.90.8-1.11.11.11.11.11.11.1
Reaction time mean AUC0.50.81.00.90.70.6-1.01.01.01.01.01.00.9
Median of all reaction times0.60.81.01.00.70.7-1.01.01.01.01.01.00.9
Reaction time omissions1.01.51.91.21.41.4-1.21.21.21.21.21.21.0
Reaction time false alarm rate5.67.88.7-2.8-2.4-2.33.0-2.9-2.9-2.9-2.9-2.9-2.8
Reaction time premature initiation rate0.00.00.1-0.1-0.0-0.0-0.30.30.30.30.30.30.1
Reaction time premature initiations0.10.30.50.20.10.1-0.70.60.60.60.60.60.5
Std. dev. reaction times0.61.01.21.00.90.8-1.11.11.11.11.11.11.0
Reaction time trials completed0.61.01.50.90.60.5-1.21.11.11.11.11.11.2
Reaction time trials AUC0.50.91.20.90.50.5-1.11.01.01.01.01.01.1
Run reversals in cocaine runway, females0.10.10.50.50.10.2-0.30.20.20.20.20.20.7
Run reversals in cocaine runway, males0.00.00.1-0.00.10.1-0.20.20.20.20.20.2-0.4
Latency to leave start box in cocaine runway0.00.00.10.1-0.3-0.30.1-0.2-0.2-0.2-0.2-0.20.2
Latency to leave start box in cocaine runway, F0.00.00.10.30.00.0-0.20.10.10.10.10.10.4
Latency to leave start box in cocaine runway, M0.00.00.00.1-0.2-0.20.1-0.1-0.1-0.1-0.1-0.10.1
Std. dev. time between licks in bursts0.00.00.10.3-0.1-0.1-0.10.10.10.10.10.10.1
Total sessions with >9 infusions0.10.10.10.30.40.3-0.30.30.30.30.30.20.0
Short access day 1 total inactive lever presses2.12.83.51.51.71.6-1.91.71.71.71.71.71.5
Short access day 10 total inactive lever presses0.00.10.2-0.5-0.3-0.30.1-0.2-0.2-0.2-0.2-0.2-0.3
Short access day 1 total infusions0.10.20.30.10.40.4-0.50.50.50.50.50.50.2
Short access day 10 total infusions0.10.10.20.10.40.3-0.40.30.30.30.30.30.1
Short access total infusions0.00.00.2-0.4-0.0-0.10.0-0.0-0.0-0.0-0.0-0.1-0.4
Short access day 1 locomotion0.10.10.2-0.4-0.3-0.30.3-0.3-0.3-0.3-0.3-0.3-0.4
Short access day 10 total locomotion0.50.91.0-1.0-1.0-1.00.9-0.9-0.9-0.9-0.9-0.9-0.9
Short access total locomotion0.80.91.1-1.1-1.0-1.00.9-0.9-0.9-0.9-1.0-1.0-1.0
One hour access (0.3 mA shock)0.20.20.5-0.3-0.2-0.20.7-0.4-0.5-0.5-0.5-0.5-0.6
Compulsive drug intake0.81.01.21.01.11.1-0.91.01.01.01.01.00.8
One hour access (shock baseline)0.20.30.4-0.6-0.4-0.50.7-0.6-0.6-0.6-0.6-0.6-0.7
Social response proportion2.42.73.71.81.91.9-1.51.51.51.51.51.51.6
Social responses1.82.33.21.81.41.4-1.51.51.51.51.51.51.4
Social time1.41.92.61.51.61.6-1.31.41.31.31.31.31.1
Soleus weight2.36.87.42.72.72.7-2.62.62.62.62.62.62.4
Bone: stiffness1.52.52.81.31.51.5-1.71.61.61.61.61.61.6
Tibialis anterior weight2.89.410.43.23.03.0-3.13.13.13.13.13.12.8
Time to tail flick, vehicle, before self-admin0.00.00.0-0.0-0.0-0.0-0.00.00.00.00.00.0-0.1
Time to tail flick, vehicle, after self-admin0.40.60.8-0.8-0.6-0.60.8-0.7-0.8-0.8-0.8-0.8-0.9
Time to tail flick, test, before self-admin0.00.00.00.10.10.1-0.10.10.10.10.10.10.1
Time to tail flick, test, after self-admin0.10.10.1-0.4-0.3-0.30.2-0.3-0.3-0.3-0.2-0.2-0.1
Delta time to tail flick, vehicle, before/after SA0.10.10.1-0.2-0.3-0.20.4-0.4-0.4-0.4-0.4-0.4-0.3
Delta time to tail flick, test, before/after SA0.40.40.6-0.8-0.7-0.70.6-0.6-0.6-0.6-0.6-0.6-0.6
Tibia length0.00.10.20.00.40.50.3-0.3-0.3-0.3-0.3-0.3-0.1
Ambulatory time before self-admin2.02.93.4-1.8-1.7-1.71.7-1.7-1.7-1.7-1.7-1.7-1.8
Ambulatory time after self-admin0.00.00.00.10.10.10.0-0.0-0.0-0.0-0.0-0.0-0.2
Bone: tissue strength1.61.62.0-1.4-0.8-0.81.3-1.4-1.4-1.4-1.4-1.4-1.2
Total heroin consumption5.26.18.02.82.52.5-2.42.52.42.42.42.52.4
Bone: trabecular number3.05.05.72.22.42.4-2.32.22.22.22.22.22.1
Bone: trabecular spacing0.30.40.5-0.6-0.5-0.50.7-0.6-0.6-0.6-0.6-0.6-0.6
Bone: trabecular thickness0.00.00.0-0.2-0.1-0.10.0-0.1-0.1-0.1-0.1-0.10.0
Bone: trabecular tissue density1.52.12.7-1.6-1.6-1.61.4-1.4-1.4-1.4-1.4-1.4-1.3
Water consumed over 24 hours0.00.00.1-0.1-0.3-0.30.1-0.1-0.1-0.1-0.1-0.10.1
Number of responses in last shaping day0.90.91.1-1.0-0.9-0.90.9-1.0-1.0-1.0-1.0-1.0-1.0