Hub : Genes

LOC120095200

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Liver	gene expression	LOC120095200	0.28	0.09	0.0e+00	0.24	0.28	0.26	0.28	1.6e-26	3.9e-31	3.2e-29	1.6e-30
2	Liver	alternative polyA	XR_005490497.2	0.34	0.11	0.0e+00	0.24	0.3	0.28	0.28	4.1e-26	4.9e-33	8.0e-31	9.5e-31
3	Liver	alternative polyA	XR_005490494.2	0.29	0.14	7.4e-07	0.06	0.05	0.03	0.05	6.5e-07	1.3e-06	4.8e-04	2.7e-06
4	pVTA	alternative polyA	XR_005490497.2	0.3	0.12	1.7e-04	0.06	0.05	0.05	0.05	2.7e-05	4.6e-05	1.2e-04	3.9e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
Bone: apparent density	0.5	1.0	3.5	-0.5	0.5	-1.9	-0.3
Area under the delay curve	0.1	0.1	0.2	-0.5	0.5	-0.2	0.2
BMI with tail	0.9	3.3	3.9	-1.9	2.0	1.9	1.4
BMI without tail	0.8	4.2	5.7	-2.3	2.4	2.3	0.9
Body weight	3.4	15.0	22.6	-4.8	4.7	1.3	3.7
Weight adjusted by age	0.4	1.3	5.0	-0.1	0.2	2.2	0.2
Bone surface	2.4	4.8	9.7	-2.1	2.1	-3.1	0.7
Bone volume	2.8	5.6	10.6	-2.3	2.4	-3.3	0.9
Breakpoint value in progressive ratio session	1.1	2.0	2.4	1.4	-1.3	1.6	-1.4
Number of licking bursts	0.2	0.6	1.5	-0.7	0.6	-0.2	1.2
Context. condit. distance diff. score	0.1	0.1	0.2	-0.4	0.4	-0.1	0.4
Locomotion velocity, session 1	0.1	0.2	0.6	-0.2	0.2	-0.1	-0.7
Locomotion distance, session 1	0.4	0.5	1.9	-0.2	0.3	-0.3	-1.4
Locomotion velocity, session 2	0.6	0.8	2.2	0.3	-0.2	-0.8	-1.5
Locomotion distance, session 2	1.1	1.6	5.8	0.5	-0.4	-0.4	-2.4
Locomotion velocity, session 3	1.9	2.2	6.7	0.9	-0.8	0.7	-2.6
Locomotion distance, session 3	0.2	0.2	0.5	-0.3	0.3	-0.4	-0.7
Stereotopy head waving bouts, day 3	5.7	6.8	9.5	3.1	-3.0	1.1	-2.7
Stereotopy head waving duration, day 3	2.6	3.2	4.6	2.1	-2.1	0.5	-1.8
Locomotion velocity, session 7	0.1	0.1	0.2	0.3	-0.3	-0.1	-0.4
Locomotion distance, session 7	1.2	1.5	2.1	-1.2	1.3	-1.5	0.9
Stereotopy head waving bouts, day 7	3.0	3.5	4.2	2.0	-2.0	1.6	-1.9
Stereotopy head waving duration, day 7	4.8	5.9	7.7	2.8	-2.7	2.0	-2.1
Locomotion velocity, session 8	0.0	0.0	0.0	-0.1	0.1	-0.1	0.2
Locomotion distance, session 8	0.5	0.7	1.8	-0.3	0.5	-0.9	-1.4
Degree of sensitization distance	0.8	0.9	1.5	-0.8	0.8	-1.2	1.0
Degree of sensitization stereotypy	1.8	2.0	2.8	1.3	-1.2	1.7	-1.4
Conditioned locomotion	0.2	0.2	0.8	-0.1	0.2	-0.9	-0.3
Cocaine response after cond. corrected	0.6	0.9	1.8	-0.8	0.8	-0.8	1.3
Cocaine response after cond. not corrected	0.9	1.3	2.9	-1.0	0.9	-0.8	1.7
Cocaine response before conditioning	0.0	0.0	0.0	0.0	-0.0	-0.1	-0.0
Saline control response	0.6	0.8	2.1	-0.4	0.5	1.4	-0.7
Bone: connectivity density	1.0	1.6	3.2	0.6	-0.5	-1.6	-1.8
Bone: cortical apparent density	3.0	4.7	6.1	2.5	-2.4	1.7	-2.0
Bone: cortical area	1.2	2.0	3.2	-1.4	1.6	-1.8	-0.6
Bone: cortical porosity	2.8	3.1	4.8	-2.1	2.2	-1.7	0.4
Bone: cortical porosity	3.2	3.6	6.2	-2.4	2.5	-1.4	0.6
Bone: cortical thickness	3.3	5.5	10.3	2.1	-1.9	2.0	-3.2
Bone: cortical thickness	3.8	4.7	10.8	2.0	-1.9	0.8	-3.3
Bone: cortical tissue density	3.0	4.8	6.1	2.5	-2.4	1.8	-2.0
Condit. Reinf. active minus inactive responses	4.0	4.5	5.8	-2.4	2.4	-2.1	1.6
Condit. Reinf. active-inactive response ratio	1.3	1.4	3.0	-1.0	0.9	-0.9	1.7
Condit. Reinf. active responses	3.7	4.8	6.3	-2.5	2.5	-2.4	0.9
Condit. Reinf. inactive responses	1.2	1.6	2.3	-1.2	1.3	-1.5	-0.9
Incentive salience index mean	1.5	1.9	2.6	-1.6	1.6	-1.4	0.7
Condit. Reinf. lever presses	0.1	0.1	0.5	-0.0	0.0	0.3	-0.7
Condit. Reinf. active minus inactive responses	3.7	5.8	8.0	-2.7	2.7	-2.8	0.6
Condit. Reinf. active-inactive response ratio	2.9	4.6	5.6	-2.4	2.3	-2.4	1.3
Condit. Reinf. active responses	5.5	7.9	10.8	-3.1	3.2	-3.3	0.9
Condit. Reinf. inactive responses	1.0	1.5	2.8	-1.0	1.2	-1.7	-0.8
Condit. Reinf. lever presses	2.3	3.3	5.1	-2.2	2.3	-1.7	0.4
Condit. Reinf. lever reinforcers received	5.3	7.5	9.9	-3.0	3.1	-3.1	1.1
Conditioned reinforcement - actives	0.1	0.3	1.0	-0.4	0.3	-1.0	-0.3
Conditioned reinforcement - inactives	0.3	0.7	1.1	-1.1	0.9	-0.6	0.6
Conditioned locomotion	2.1	3.2	5.0	-2.2	2.2	-1.3	1.1
Patch foraging indifference point 0 sec	1.6	4.6	7.6	-2.7	2.8	-1.9	0.1
Patch foraging indifference point AUC	0.3	0.8	1.1	-1.1	1.0	-0.6	0.8
Delay disc. indifference point, 0s delay	0.1	0.1	0.3	0.2	-0.2	0.6	0.2
Delay disc. indifference point, 16s delay	0.4	0.5	1.2	-0.6	0.6	0.2	1.1
Delay disc. indifference point, 2s delay	0.1	0.1	0.2	-0.3	0.4	-0.3	-0.2
Delay disc. indifference point, 24s delay	0.8	1.3	1.7	-1.3	1.3	-1.0	0.7
Delay disc. indifference point, 4s delay	0.0	0.0	0.1	0.1	0.0	0.0	-0.3
Delay disc. indifference point, 8s delay	0.3	0.5	0.7	0.8	-0.8	0.9	-0.4
Indifference point function ln k	0.5	1.5	3.8	0.8	-0.6	-1.1	-1.9
Indifference point function log k	0.5	1.5	3.8	0.8	-0.6	-1.1	-1.9
Patch foraging total patch changes 0 sec	1.3	3.7	6.2	-2.4	2.5	-1.6	-0.1
Patch foraging total patch changes 12 sec	2.8	3.7	5.6	-2.4	2.3	-1.7	1.0
Patch foraging total patch changes 18 sec	0.4	1.0	2.0	-1.4	1.4	-0.4	-0.0
Patch foraging total patch changes 24 sec	1.2	4.1	6.0	-2.4	2.4	-2.1	-0.1
Patch foraging total patch changes 6 sec	4.9	8.3	13.2	-3.6	3.6	-2.2	1.5
Patch foraging time to switch 0 sec	0.2	0.6	1.3	0.0	-0.1	1.0	1.1
Patch foraging water rate 0 sec	0.4	1.6	2.3	-1.3	1.4	-1.5	-0.3
Patch foraging water rate 12 sec	0.0	0.2	0.5	-0.1	0.1	0.2	-0.7
Patch foraging water rate 18 sec	0.4	1.0	3.0	0.6	-0.5	-0.4	-1.7
Patch foraging water rate 24 sec	0.6	0.9	2.6	0.6	-0.5	-0.6	-1.6
Patch foraging water rate 6 sec	0.8	1.1	3.3	0.8	-0.7	-0.1	-1.8
Seeking ratio, delayed vs. immediate footshock	0.6	0.8	1.1	-1.0	1.0	0.4	1.0
Distance traveled before self-admin	0.3	0.7	1.0	0.7	-0.6	0.9	-1.0
Distance traveled after self-admin	0.1	0.1	0.2	-0.3	0.5	-0.0	0.3
Extensor digitorum longus weight	1.2	4.9	15.7	0.7	-0.9	4.0	1.7
Bone: elastic displacement	1.7	2.2	4.7	1.3	-1.2	1.0	-2.2
Bone: elastic work	0.5	0.7	1.8	0.2	-0.2	0.9	-1.3
Bone: endosteal estimation	12.7	31.0	37.3	-6.1	6.0	-5.5	4.6
Bone: endosteal perimeter	13.6	33.3	39.8	-6.3	6.2	-5.9	4.5
Epididymis fat weight	1.0	5.1	8.5	-1.4	1.3	2.9	2.9
Delta time in closed arm before/after self-admin	0.2	0.2	0.5	0.3	-0.4	-0.7	0.2
Delta time in open arm before/after self-admin	0.9	1.0	1.9	1.0	-1.0	0.1	-1.4
Diff in mean of infusions in LGA sessions	0.7	1.2	2.7	1.0	-1.0	1.7	-0.5
Delay discount exponential model param	0.3	0.4	0.6	0.7	-0.8	0.5	-0.5
Extinction: sum of active levers before priming	0.2	0.3	0.4	-0.5	0.6	0.4	0.6
Active lever presses in extinction session 6	0.0	0.0	0.1	-0.1	0.2	0.0	-0.4
Bone: final force	0.6	1.0	1.8	-1.0	1.0	-1.3	-0.2
Bone: final moment	0.6	1.0	2.0	-0.9	1.0	-1.4	-0.3
Food consumed during 24 hour testing period	0.5	1.1	2.6	0.6	-0.5	1.6	-1.1
Glucose	0.0	0.0	0.1	0.1	-0.0	0.3	0.3
Heart weight	0.9	1.4	2.9	-1.6	1.7	-0.2	0.3
Delay discount hyperbolic model param	0.3	0.3	0.5	0.7	-0.7	0.4	-0.5
Intermittent access intake day 1-15 change	0.6	3.4	9.5	-1.5	1.3	-0.1	3.1
Intermittent access intake escalation	0.6	3.0	7.8	-1.6	1.4	-0.1	2.8
Intermittent access intake escalation 2	2.2	3.7	8.8	-1.8	1.6	-0.7	3.0
Intermitt. access day 1 inactive lever presses	0.1	0.9	1.4	-1.2	1.1	-0.2	1.0
Intermitt. access day 15 inactive lever presses	0.3	1.3	3.5	-0.7	0.5	1.1	1.9
Intermitt. access escalation Index	0.1	0.3	0.6	0.5	-0.4	0.7	-0.2
Intermittent access day 1 total infusions	0.2	0.5	1.5	-0.4	0.4	-0.5	-1.2
Intermittent access day 15 total infusions	0.9	2.2	3.6	-1.9	1.8	-0.5	1.4
Intermittent access terminal intake (last 3 days)	1.9	3.4	5.0	-2.2	2.1	-1.1	1.8
Intermittent access total infusions	1.1	1.3	2.2	-1.5	1.3	-1.0	0.4
Intermittent access day 1 locomotion	1.1	2.0	3.7	-1.9	1.8	-0.7	0.6
Intermittent access day 15 total locomotion	0.8	3.3	5.0	-2.2	2.1	-1.4	1.2
Intermittent access total locomotion	4.0	4.8	8.3	-2.9	2.7	-1.5	1.0
Intermittent access standard deviation	0.9	4.5	10.0	-2.1	1.8	-0.4	3.2
Left kidney weight	0.0	0.3	0.5	-0.7	0.7	0.3	0.0
Right kidney weight	0.1	0.5	0.7	-0.8	0.9	0.7	0.1
Cocaine induced anxiety	0.1	0.3	1.3	-0.2	0.2	-1.1	0.0
Post-drug Anxiety	0.3	0.3	0.8	0.4	-0.3	-0.5	-0.9
Baseline Anxiety	1.0	1.8	2.5	1.2	-1.0	1.5	-1.6
Tail length	0.6	3.2	5.8	-2.4	2.4	0.0	1.0
Length with tail	1.9	8.3	12.0	-3.5	3.3	-0.0	3.2
Length without tail	0.8	4.0	8.6	-2.0	1.8	0.5	2.9
Times rat made contact with spout	0.1	0.2	0.2	-0.5	0.5	0.4	0.2
Lifetime Intake	0.7	0.9	1.5	-1.2	1.1	-0.9	-0.3
Liver weight, left	1.7	3.0	4.0	-2.0	2.0	-1.7	1.0
Liver weight, right	0.3	0.6	1.7	0.5	-0.5	1.3	-0.1
Locomotor activity	0.9	1.5	2.0	-1.3	1.4	-1.0	-1.1
Locomotor testing distance	0.6	1.5	2.2	-1.3	1.5	-0.7	-1.2
Locomotor testing rearing	0.2	0.8	1.6	-1.1	1.2	-0.0	-0.7
Locomotion in novel chamber	0.7	0.9	1.6	0.9	-0.9	1.3	-0.7
Locomotion in novel chamber post-restriction	0.0	0.1	0.2	0.2	-0.3	0.2	0.4
Fecal boli incidents, locomotor time 1	0.7	1.7	4.1	-1.0	0.9	-0.9	2.0
Change in fecal boli incidents, locomotor task	0.1	0.1	0.1	0.4	-0.4	0.3	0.3
Time >=10cm from walls, locomotor time 1	0.5	0.7	1.3	1.0	-1.1	0.3	-0.5
Bouts of movement, locomotor time 1	0.1	0.1	0.3	-0.3	0.3	0.5	-0.1
Total resting periods, locomotor time 1	0.1	0.2	0.3	-0.3	0.2	0.5	0.5
Rest time, locomotor task time 1	0.3	0.6	0.9	0.5	-0.6	0.8	1.0
Distance moved, locomotor task time 1	0.2	0.6	0.9	0.6	-0.6	0.9	-0.9
Vertical activity count, locomotor time 1	0.0	0.3	0.5	0.5	-0.4	0.5	-0.7
Time >=10cm from walls, locomotor time 2	0.8	2.3	5.6	1.3	-1.3	2.4	-0.4
Bouts of movement, locomotor time 2	0.2	0.8	2.4	0.1	0.0	1.6	-0.8
Total resting periods, locomotor time 2	0.1	0.5	1.4	-0.1	0.1	1.2	-0.7
Rest time, locomotor task time 2	0.7	1.2	2.4	1.4	-1.5	0.5	0.4
Distance moved, locomotor task time 2	1.7	2.2	5.0	1.3	-1.2	2.2	-1.0
Vertical activity count, locomotor time 2	0.1	0.2	0.8	-0.1	0.1	0.9	-0.4
Light reinforcement 1	0.3	1.3	4.6	0.6	-0.5	0.4	-2.1
Light reinforcement 2	0.0	0.1	0.2	0.3	-0.3	0.4	-0.3
Bone: marrow area	12.0	29.5	35.4	-5.9	5.8	-5.3	4.5
Bone: maximum diameter	4.1	8.3	12.3	-3.0	3.0	-3.5	1.6
Bone: maximum force	1.7	3.4	4.8	-2.0	2.1	-2.2	0.2
Bone: maximum moment	1.8	3.4	5.2	-2.0	2.1	-2.3	0.3
Mean time between licks in bursts	0.3	2.1	5.3	-1.2	1.1	0.5	2.3
Mean num. licks in bursts	0.1	0.4	1.1	0.4	-0.3	0.3	-1.1
Cd content in liver	1.8	2.0	4.5	1.0	-1.2	0.9	2.1
Co content in liver	0.6	0.7	2.0	0.5	-0.6	1.4	0.3
Cu content in liver	0.2	0.2	0.4	-0.4	0.4	-0.5	0.6
Fe content in liver	0.5	0.6	1.3	-0.6	0.6	-1.1	-0.5
K content in liver	0.1	0.1	0.3	0.3	-0.3	-0.4	-0.5
Mg content in liver	1.2	1.3	1.9	1.4	-1.3	-0.2	-1.3
Mn content in liver	2.3	2.6	6.0	1.5	-1.4	-0.6	-2.4
Na content in liver	0.3	0.4	0.6	0.7	-0.7	0.2	-0.8
Rb content in liver	0.9	1.0	1.7	1.3	-1.3	0.3	-0.8
Se content in liver	1.0	1.2	3.1	1.0	-0.9	0.3	-1.8
Sr content in liver	0.5	0.4	0.7	-0.8	0.8	0.3	0.6
Zn content in liver	0.2	0.2	0.7	-0.2	0.2	-0.9	0.2
Bone: minimum diameter	11.9	22.9	29.2	-5.4	5.4	-4.7	3.3
Time in familiar zone, hab. session 1	2.3	2.5	4.8	-1.5	1.4	-1.0	2.2
Time in novel zone, hab. session 1	1.2	1.3	3.1	1.0	-0.9	0.5	-1.8
Total zone transitions, hab. session 1	0.2	0.3	0.9	-0.2	0.3	0.6	-0.9
Total locomotion distance, hab. session 1	0.4	0.6	2.1	0.2	-0.1	0.5	-1.5
Locomotion velocity, hab. session 1	0.4	0.6	1.9	0.3	-0.2	0.6	-1.4
Time in familiar zone, hab. session 2	1.9	2.1	2.5	-1.6	1.6	-1.3	1.4
Time in novel zone, hab. session 2	2.4	2.7	3.6	1.9	-1.9	0.7	-1.7
Total zone transitions, hab. session 2	0.6	0.7	1.5	0.2	-0.1	1.2	-1.2
Total locomotion distance, hab. session 2	1.2	1.5	2.7	0.8	-0.7	1.5	-1.6
Locomotion velocity, hab. session 2	1.6	2.1	3.3	1.1	-1.0	1.6	-1.8
Novel to familiar place preference ratio	2.6	3.4	4.9	-2.2	2.2	-1.2	1.5
Novelty place preference	1.8	2.3	3.3	-1.8	1.8	-1.0	1.2
Time in novel zone, NPP test	1.8	2.2	3.1	-1.8	1.8	-1.3	1.0
Total zone transitions, NPP test	0.9	1.3	5.0	0.5	-0.3	-0.0	-2.2
Total locomotion distance, NPP test	1.3	1.8	5.7	1.0	-0.8	0.2	-2.4
Locomotion velocity, NPP test	1.0	1.5	4.5	0.8	-0.7	0.5	-2.1
Intraocular pressure	0.7	1.1	2.1	-1.3	1.5	-0.7	-0.3
Delta distance traveled before/after self-admin	0.1	0.1	0.2	-0.4	0.5	-0.4	0.1
Delta ambulatory time before/after self-admin	0.7	1.1	1.4	-1.1	1.2	-1.2	0.8
Parametrial fat weight	0.3	0.7	1.9	0.7	-0.8	-0.0	1.4
Pavlov. Cond. lever latency	0.5	0.7	1.1	1.0	-1.0	-0.6	0.4
Pavlov. Cond. magazine entry latency	0.7	0.8	1.4	-1.2	1.2	-0.8	0.1
Pavlov. Cond. change in total contacts	1.0	1.0	2.1	-1.4	1.5	-0.3	0.1
Pavlov. Cond. index score	0.8	1.0	2.0	-1.4	1.4	-0.5	0.1
Pavlov. Cond. latency score	0.8	1.0	2.0	-1.4	1.4	-0.2	0.1
Pavlov. Cond. lever contacts	0.5	0.6	0.8	-0.9	0.9	0.8	-0.1
Pavlov. Cond. magazine entry number	0.7	0.8	1.3	1.1	-1.1	0.9	-0.2
Pavlov. Cond. intertrial magazine entries	4.0	4.8	7.9	-2.7	2.8	-1.9	0.7
Pavlov. Cond. lever-magazine prob. diff.	0.8	1.0	1.9	-1.3	1.4	-0.7	-0.1
Pavlov. Cond. response bias	0.4	0.5	0.8	-0.9	0.9	-0.5	-0.2
Pavlov. Cond. lever latency	0.9	1.3	2.6	1.1	-1.1	1.6	0.1
Pavlov. Cond. magazine entry latency	0.1	0.1	0.2	-0.1	0.1	-0.5	0.5
Pavlov. Cond. change in total contacts	0.5	1.3	2.5	-1.1	1.1	-1.6	0.1
Pavlov. Cond. index score	0.9	1.5	2.6	-1.2	1.3	-1.6	0.4
Pavlov. Cond. latency score	0.8	1.3	2.6	-1.1	1.1	-1.6	0.3
Pavlov. Cond. lever contacts	0.7	1.0	2.1	-0.9	1.0	-1.4	-0.5
Pavlov. Cond. magazine entry number	0.0	0.0	0.0	-0.1	0.1	0.1	-0.0
Pavlov. Cond. intertrial magazine entries	0.3	0.6	0.9	-0.9	0.9	-1.0	0.0
Pavlov. Cond. lever-magazine prob. diff.	0.9	1.4	2.8	-1.2	1.2	-1.7	0.3
Pavlov. Cond. response bias	0.8	1.1	2.3	-1.0	1.0	-1.5	-0.2
Time in closed arm before self-admin	0.2	0.3	0.6	-0.1	0.3	0.8	-0.7
Time in closed arm after self-admin	0.4	0.4	1.5	0.2	-0.2	1.2	0.4
Time in open arm before self-admin	0.5	0.6	1.5	-0.4	0.3	0.9	1.2
Time in open arm after self-admin	0.1	0.1	0.2	-0.5	0.4	-0.3	0.2
Bone: periosteal estimation	8.4	19.9	24.6	-5.0	4.9	-4.9	2.7
Bone: periosteal perimeter	6.9	13.6	16.6	-4.1	4.1	-3.8	2.6
Bone: post-yield work	2.8	4.8	6.6	-2.6	2.5	-1.7	1.7
Progressive ratio test 1 active lever presses	0.4	0.6	0.9	-1.0	0.9	0.4	-0.8
Progressive ratio test 1 breakpoint	0.4	0.6	1.0	-1.0	1.0	0.3	-0.8
Progressive ratio test 1 inactive lever presses	0.6	1.7	3.4	-1.8	1.8	-0.2	0.1
Progressive ratio test 2 active lever presses	0.1	0.2	0.3	-0.6	0.5	0.0	-0.3
Progressive ratio test 2 breakpoint	0.1	0.2	0.4	-0.6	0.5	0.0	-0.3
Progressive ratio test 2 inactive lever presses	0.0	0.1	0.2	-0.5	0.4	0.2	0.0
Incentive Sensitization - Responses	0.0	0.0	0.1	-0.3	0.3	-0.2	0.1
Incentive Sensitization - Breakpoint	0.0	0.0	0.1	-0.2	0.2	-0.1	0.1
Sum of active levers in priming session hrs 5-6	0.5	0.4	0.9	0.6	-0.6	1.0	0.1
Progressive ratio	0.1	0.2	0.4	-0.3	0.3	-0.2	0.6
Food seeking constrained by brief footshock	0.3	0.4	0.6	-0.6	0.6	-0.5	0.7
Seeking ratio, punishment vs. effort	0.0	0.1	0.1	-0.3	0.3	-0.3	-0.3
Retroperitoneal fat weight	0.7	3.1	5.3	-1.0	0.9	2.2	2.3
Reaction time number correct	0.2	0.5	1.0	0.7	-0.7	-0.5	-1.0
Reaction time mean minus median	0.2	1.6	3.4	0.5	-0.6	1.8	1.6
Reaction time mean minus median AUC	0.1	0.4	0.5	0.6	-0.7	0.7	0.6
Reaction time num false alarms	3.0	5.2	7.6	-2.6	2.8	-2.5	0.1
Reaction time num false alarms AUC	2.3	5.3	7.6	-2.6	2.8	-2.6	0.2
Reaction time trials correct on left	0.2	0.5	1.0	0.7	-0.7	-0.5	-1.0
Reaction time trials on left	0.1	0.5	0.8	0.7	-0.6	-0.5	-0.9
Reaction time mean	0.4	0.8	1.2	1.0	-1.1	0.8	0.7
Reaction time mean AUC	0.5	1.2	1.7	1.2	-1.3	1.1	0.6
Median of all reaction times	0.5	0.7	1.5	1.1	-1.2	0.3	0.3
Reaction time omissions	0.3	0.4	1.5	0.1	-0.3	0.4	1.2
Reaction time false alarm rate	3.1	4.3	6.8	-2.5	2.6	-1.9	0.7
Reaction time premature initiation rate	1.9	3.0	4.6	-2.1	2.2	-1.3	1.1
Reaction time premature initiations	0.6	1.9	2.6	-1.5	1.6	-1.6	0.4
Std. dev. reaction times	0.4	1.4	2.3	0.9	-1.1	1.3	1.5
Reaction time trials completed	0.1	0.5	0.8	0.7	-0.6	-0.5	-0.9
Reaction time trials AUC	0.1	0.5	0.7	0.8	-0.7	-0.4	-0.9
Run reversals in cocaine runway, females	2.0	2.2	6.9	0.2	-0.3	2.6	1.3
Run reversals in cocaine runway, males	0.1	0.1	0.3	0.0	0.0	0.1	0.5
Latency to leave start box in cocaine runway	2.4	3.4	5.3	1.7	-1.6	1.6	-2.3
Latency to leave start box in cocaine runway, F	1.2	1.5	2.4	1.0	-0.8	1.4	-1.6
Latency to leave start box in cocaine runway, M	2.8	2.7	3.5	1.7	-1.7	1.1	-1.9
Std. dev. time between licks in bursts	0.6	1.1	1.7	1.1	-1.1	1.3	-0.4
Total sessions with >9 infusions	0.3	0.4	1.3	-0.1	0.1	0.7	-1.1
Short access day 1 total inactive lever presses	0.1	0.3	1.0	-0.1	0.1	0.0	-1.0
Short access day 10 total inactive lever presses	0.1	0.4	1.5	-0.3	0.1	-0.0	1.2
Short access day 1 total infusions	0.5	1.0	4.2	0.0	0.1	0.1	-2.0
Short access day 10 total infusions	0.8	1.3	2.6	-1.6	1.6	-0.5	-0.2
Short access total infusions	0.6	0.8	1.8	-0.7	0.7	-0.6	-1.4
Short access day 1 locomotion	0.3	0.6	0.8	-0.8	0.9	0.5	-0.7
Short access day 10 total locomotion	0.7	2.7	4.4	-2.1	2.0	-0.3	1.6
Short access total locomotion	0.7	1.0	2.0	-1.4	1.3	0.3	0.5
One hour access (0.3 mA shock)	1.5	1.8	2.8	-1.5	1.4	-1.7	0.5
Compulsive drug intake	1.0	1.5	2.4	-1.2	1.2	-1.6	0.8
One hour access (shock baseline)	0.1	0.1	0.3	-0.5	0.4	-0.3	0.1
Social response proportion	0.8	1.1	1.9	-1.0	1.1	-0.4	1.4
Social responses	1.1	1.5	2.2	-1.5	1.5	-1.0	0.7
Social time	0.9	1.4	3.8	-0.9	0.9	-0.3	1.9
Soleus weight	0.5	1.6	2.4	-1.6	1.5	0.2	1.2
Bone: stiffness	1.0	1.7	2.8	-1.3	1.4	-1.7	0.7
Tibialis anterior weight	0.4	1.5	4.1	-0.7	0.7	2.0	0.9
Time to tail flick, vehicle, before self-admin	0.4	0.5	1.9	0.0	-0.2	0.2	1.4
Time to tail flick, vehicle, after self-admin	0.1	0.2	0.2	-0.4	0.4	-0.5	0.4
Time to tail flick, test, before self-admin	1.6	1.9	3.0	-1.6	1.7	-0.8	1.1
Time to tail flick, test, after self-admin	1.4	1.5	1.8	-1.2	1.2	-1.1	1.4
Delta time to tail flick, vehicle, before/after SA	0.2	0.2	0.7	-0.3	0.3	-0.8	-0.1
Delta time to tail flick, test, before/after SA	0.3	0.4	0.8	-0.1	-0.0	-0.9	0.9
Tibia length	0.4	1.2	1.5	-1.1	1.0	1.2	1.1
Ambulatory time before self-admin	0.5	1.6	2.1	1.2	-1.1	1.5	-1.4
Ambulatory time after self-admin	0.0	0.0	0.1	0.0	0.2	0.2	-0.3
Bone: tissue strength	1.5	1.5	3.9	1.1	-1.0	0.4	-2.0
Total heroin consumption	0.1	0.1	0.2	0.2	-0.3	-0.0	-0.4
Bone: trabecular number	0.7	1.3	3.4	0.2	-0.1	-1.8	-1.4
Bone: trabecular spacing	0.3	0.4	1.1	0.2	-0.2	1.0	0.6
Bone: trabecular thickness	1.5	2.0	4.0	-1.3	1.4	-2.0	0.6
Bone: trabecular tissue density	0.3	0.5	1.0	0.7	-0.7	1.0	-0.1
Water consumed over 24 hours	1.0	1.9	3.0	1.3	-1.3	1.2	-1.7
Number of responses in last shaping day	0.6	0.8	2.6	0.1	-0.2	1.6	0.6