Hub : Genes

LOC120093525

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC alternative TSS XM_039080002.1 0.14 0.1 5.2e-03 0.07 0.08 0.08 0.08 8.5e-03 5.9e-03 6.5e-03 7.2e-03
2 Liver gene expression LOC120093525 0.04 0.03 1.6e-04 0.03 0.02 0.03 0.02 4.2e-04 1.5e-03 6.2e-04 1.0e-03
3 Liver alternative TSS XM_039080001.1 0.04 0.03 4.0e-04 0.02 0.02 0.02 0.02 3.7e-03 2.3e-03 1.5e-03 2.9e-03
4 NAcc alternative TSS XM_039080005.1 0.02 0.02 4.1e-03 0.02 0.02 0.01 0.02 1.6e-03 2.9e-03 6.0e-03 3.9e-03
5 NAcc alternative TSS XM_039080006.1 0.02 0.01 9.0e-03 0.02 0.01 0.01 0.01 4.4e-03 6.6e-03 2.0e-02 1.2e-02
6 NAcc isoform ratio XM_039080005.1 0.03 0.02 4.2e-04 0.01 0.02 0.02 0.02 5.9e-03 1.7e-03 7.9e-04 2.0e-03
7 Brain gene expression LOC120093525 0.08 0.06 5.0e-05 0.04 0.04 0.04 0.04 7.0e-05 9.7e-05 5.9e-05 1.4e-04
8 PL gene expression LOC120093525 0.07 0.05 7.5e-06 0.01 0.05 0.05 0.04 8.7e-03 3.2e-06 4.1e-06 1.0e-05
9 NAcc gene expression LOC120093525 0.04 0.03 1.4e-03 0.02 0.03 0.02 0.02 4.9e-03 4.2e-04 2.1e-03 3.8e-03
10 PL intron excision ratio chr7_917167_918155 0.03 0.02 4.2e-03 0.02 0.02 0.01 0.01 1.8e-03 6.4e-03 9.2e-03 8.7e-03
11 NAcc alternative TSS XM_039080005.1 0.02 0.02 8.3e-03 0.02 0.01 0.01 0.01 3.5e-03 1.2e-02 1.6e-02 1.7e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density2.13.67.2-0.6-1.0-0.71.0-1.02.0-1.92.52.72.72.7
Area under the delay curve0.10.10.30.1-0.1-0.1-0.30.30.4-0.30.50.50.50.5
BMI with tail4.614.827.05.15.0-5.2-4.94.9-3.5-4.12.31.6-0.7-0.6
BMI without tail1.02.13.82.02.0-1.7-1.91.9-1.7-1.00.3-0.0-0.9-0.8
Body weight0.83.57.02.52.3-2.3-2.72.7-1.7-1.71.00.6-0.5-0.4
Weight adjusted by age0.20.30.70.20.40.1-0.30.3-0.50.4-0.7-0.7-0.8-0.7
Bone surface4.47.815.3-1.4-1.8-0.72.1-2.13.1-2.43.43.73.93.9
Bone volume4.67.815.3-1.1-1.6-0.91.8-1.83.0-2.73.63.83.93.9
Breakpoint value in progressive ratio session1.31.42.9-1.5-1.31.71.2-1.20.61.6-1.2-1.0-0.5-0.3
Number of licking bursts2.63.15.62.32.3-1.8-2.42.4-2.1-0.8-0.1-0.4-1.4-1.4
Context. condit. distance diff. score0.10.20.30.60.6-0.5-0.50.5-0.4-0.30.10.0-0.2-0.2
Locomotion velocity, session 10.91.02.3-0.0-0.3-0.50.1-0.10.9-1.11.51.51.41.4
Locomotion distance, session 11.31.73.4-0.8-1.00.01.0-1.01.6-0.91.51.61.81.8
Locomotion velocity, session 22.42.85.0-1.6-1.70.61.8-1.82.2-0.51.31.62.12.1
Locomotion distance, session 22.73.87.4-2.3-2.51.52.1-2.12.70.30.91.32.12.1
Locomotion velocity, session 32.83.36.4-2.4-2.32.52.2-2.21.62.0-1.2-0.90.20.2
Locomotion distance, session 30.10.10.1-0.2-0.20.40.0-0.0-0.00.4-0.4-0.4-0.2-0.2
Stereotopy head waving bouts, day 33.74.48.1-2.8-2.72.62.8-2.82.31.7-0.7-0.21.01.0
Stereotopy head waving duration, day 32.63.16.6-2.3-2.12.02.6-2.61.81.3-0.6-0.20.80.8
Locomotion velocity, session 70.20.20.4-0.4-0.40.10.6-0.60.6-0.20.40.50.60.6
Locomotion distance, session 70.30.40.80.40.6-0.1-0.40.4-0.70.4-0.7-0.8-0.9-0.9
Stereotopy head waving bouts, day 71.21.32.3-1.2-1.40.71.2-1.21.5-0.10.81.01.41.4
Stereotopy head waving duration, day 71.31.62.7-1.2-1.40.61.1-1.11.6-0.31.11.31.71.7
Locomotion velocity, session 82.12.65.0-1.5-1.80.81.5-1.52.2-0.31.31.52.02.0
Locomotion distance, session 80.30.41.0-0.8-0.90.60.6-0.61.00.20.30.40.70.7
Degree of sensitization distance0.30.30.70.70.7-0.8-0.50.5-0.4-0.70.40.3-0.0-0.0
Degree of sensitization stereotypy0.50.51.20.1-0.2-0.4-0.10.10.5-0.81.11.11.01.0
Conditioned locomotion1.61.93.81.41.5-0.6-1.61.6-1.90.3-0.9-1.2-1.6-1.7
Cocaine response after cond. corrected2.42.74.61.92.1-1.2-2.12.1-2.1-0.3-0.6-1.0-1.7-1.7
Cocaine response after cond. not corrected2.73.05.11.92.2-1.2-2.12.1-2.2-0.3-0.8-1.1-1.8-1.8
Cocaine response before conditioning0.40.51.0-0.9-1.00.71.0-1.00.80.30.00.20.50.6
Saline control response0.40.51.00.80.8-0.6-1.01.0-0.9-0.3-0.0-0.2-0.5-0.5
Bone: connectivity density1.32.04.0-0.5-0.8-0.50.8-0.81.5-1.31.82.02.02.0
Bone: cortical apparent density0.81.12.31.41.4-1.5-1.21.2-0.9-1.10.60.4-0.3-0.3
Bone: cortical area1.32.04.50.70.4-1.7-0.20.20.4-2.12.12.11.51.5
Bone: cortical porosity0.30.30.6-0.3-0.3-0.20.5-0.50.7-0.60.60.70.80.8
Bone: cortical porosity0.70.71.6-0.0-0.1-0.70.2-0.20.7-1.21.21.31.11.1
Bone: cortical thickness0.91.53.61.31.1-1.9-0.90.9-0.5-1.81.51.40.60.6
Bone: cortical thickness0.60.71.31.11.1-0.9-1.01.0-1.1-0.4-0.0-0.2-0.7-0.7
Bone: cortical tissue density0.60.81.61.21.2-1.3-1.11.1-0.8-0.90.40.2-0.3-0.3
Condit. Reinf. active minus inactive responses1.31.53.0-1.6-1.41.41.7-1.71.31.0-0.5-0.20.40.4
Condit. Reinf. active-inactive response ratio0.30.30.6-0.5-0.20.60.5-0.5-0.00.7-0.8-0.7-0.5-0.5
Condit. Reinf. active responses2.32.85.4-2.2-2.11.62.3-2.32.20.70.10.41.31.3
Condit. Reinf. inactive responses1.72.03.7-1.6-1.81.01.7-1.71.90.20.70.91.51.5
Incentive salience index mean1.21.52.8-1.5-1.51.01.6-1.61.70.30.30.61.11.1
Condit. Reinf. lever presses1.52.14.1-0.9-1.20.10.9-0.91.9-0.91.71.82.02.0
Condit. Reinf. active minus inactive responses1.51.93.7-1.4-1.11.81.3-1.30.21.9-1.8-1.5-0.8-0.8
Condit. Reinf. active-inactive response ratio1.61.63.9-0.3-0.01.20.1-0.1-0.81.7-2.0-1.9-1.6-1.6
Condit. Reinf. active responses0.81.22.2-1.4-1.21.41.5-1.50.71.2-0.9-0.6-0.10.0
Condit. Reinf. inactive responses0.40.50.9-0.8-0.80.40.9-0.90.9-0.00.40.60.80.8
Condit. Reinf. lever presses1.72.34.7-1.8-1.52.21.5-1.50.62.1-1.7-1.5-0.7-0.6
Condit. Reinf. lever reinforcers received0.70.91.6-1.2-0.91.31.1-1.10.41.3-1.1-0.9-0.4-0.3
Conditioned reinforcement - actives0.40.40.7-0.4-0.3-0.30.8-0.80.7-0.60.60.80.80.8
Conditioned reinforcement - inactives1.11.32.71.31.7-1.0-1.01.0-1.6-0.4-0.6-0.7-1.2-1.2
Conditioned locomotion1.92.36.0-2.0-1.61.52.4-2.41.51.0-0.6-0.20.70.6
Patch foraging indifference point 0 sec2.23.57.82.42.2-2.8-2.02.0-1.4-2.51.61.30.10.2
Patch foraging indifference point AUC0.30.30.9-0.8-0.60.90.5-0.50.60.7-0.5-0.40.0-0.1
Delay disc. indifference point, 0s delay2.12.35.30.80.4-1.4-0.80.80.8-2.12.32.21.81.9
Delay disc. indifference point, 16s delay0.20.20.3-0.5-0.60.60.5-0.50.60.3-0.00.00.30.3
Delay disc. indifference point, 2s delay0.40.51.10.30.1-0.6-0.50.50.4-0.91.11.00.70.8
Delay disc. indifference point, 24s delay0.20.20.50.60.3-0.4-0.70.7-0.2-0.40.50.30.20.1
Delay disc. indifference point, 4s delay0.70.81.5-0.8-1.00.40.7-0.71.2-0.20.80.91.21.2
Delay disc. indifference point, 8s delay0.30.30.70.50.5-0.0-0.80.8-0.50.3-0.5-0.6-0.7-0.7
Indifference point function ln k0.10.10.40.50.5-0.6-0.20.2-0.5-0.40.10.1-0.3-0.1
Indifference point function log k0.10.10.40.50.5-0.6-0.20.2-0.5-0.40.10.1-0.3-0.1
Patch foraging total patch changes 0 sec2.03.37.12.32.3-2.7-2.02.0-1.5-2.31.41.1-0.10.1
Patch foraging total patch changes 12 sec1.41.83.51.71.9-1.4-1.81.8-1.6-0.8-0.0-0.3-0.9-1.0
Patch foraging total patch changes 18 sec0.00.00.10.20.2-0.2-0.20.2-0.0-0.20.10.00.1-0.0
Patch foraging total patch changes 24 sec0.40.50.90.80.6-0.9-0.80.8-0.2-1.00.80.70.40.3
Patch foraging total patch changes 6 sec1.11.73.71.71.7-1.9-1.41.4-1.1-1.60.90.7-0.1-0.1
Patch foraging time to switch 0 sec0.30.41.10.40.1-0.7-0.30.30.2-0.81.01.00.90.7
Patch foraging water rate 0 sec0.71.12.11.11.4-0.7-1.11.1-1.5-0.2-0.6-0.8-1.3-1.1
Patch foraging water rate 12 sec0.91.42.81.31.5-0.9-1.31.3-1.7-0.2-0.6-0.8-1.5-1.2
Patch foraging water rate 18 sec2.02.76.10.50.80.5-0.80.8-1.81.5-2.2-2.3-2.5-2.2
Patch foraging water rate 24 sec3.75.19.51.92.2-0.7-2.32.3-3.00.8-2.0-2.3-3.1-2.8
Patch foraging water rate 6 sec1.01.43.5-0.30.00.90.3-0.3-0.81.5-1.9-1.8-1.6-1.5
Seeking ratio, delayed vs. immediate footshock1.21.43.1-1.5-1.40.91.8-1.81.40.30.20.50.91.0
Distance traveled before self-admin0.60.61.4-1.1-1.21.00.9-0.90.90.7-0.2-0.00.30.5
Distance traveled after self-admin0.20.20.4-0.6-0.60.40.6-0.60.40.20.10.20.50.4
Extensor digitorum longus weight3.815.027.15.25.2-4.4-5.25.2-4.4-2.80.7-0.1-2.2-2.1
Bone: elastic displacement0.00.00.1-0.1-0.1-0.00.3-0.30.2-0.10.20.20.30.3
Bone: elastic work0.50.61.30.70.4-1.1-0.50.5-0.0-1.11.21.10.70.7
Bone: endosteal estimation0.51.12.90.90.8-1.6-0.40.4-0.1-1.71.41.30.80.8
Bone: endosteal perimeter0.61.32.1-0.9-0.90.11.3-1.31.5-0.71.01.21.51.5
Epididymis fat weight0.10.20.4-0.3-0.30.60.2-0.2-0.00.6-0.6-0.6-0.5-0.3
Delta time in closed arm before/after self-admin2.92.95.41.31.7-0.4-1.51.5-2.20.8-1.7-1.9-2.3-2.3
Delta time in open arm before/after self-admin0.90.91.41.10.8-1.2-1.21.2-0.6-1.11.00.80.20.3
Diff in mean of infusions in LGA sessions1.31.42.6-1.6-1.41.61.5-1.50.91.4-1.0-0.70.00.0
Delay discount exponential model param0.10.10.2-0.00.20.00.3-0.3-0.40.2-0.4-0.4-0.4-0.4
Extinction: sum of active levers before priming2.32.35.7-1.4-1.22.20.9-0.90.22.4-2.0-1.9-1.0-1.1
Active lever presses in extinction session 60.80.81.7-1.2-1.31.11.0-1.01.20.7-0.10.00.50.5
Bone: final force1.93.16.81.81.3-2.5-1.31.3-0.4-2.62.32.11.21.2
Bone: final moment1.93.06.71.71.3-2.5-1.31.3-0.4-2.62.32.11.21.2
Food consumed during 24 hour testing period0.30.30.60.70.7-0.7-0.80.8-0.5-0.60.40.3-0.1-0.1
Glucose1.21.83.31.81.7-1.7-1.81.8-1.3-1.40.70.4-0.4-0.4
Heart weight0.10.10.30.20.5-0.1-0.10.1-0.30.0-0.4-0.4-0.5-0.5
Delay discount hyperbolic model param0.20.20.4-0.20.00.20.4-0.4-0.30.4-0.6-0.5-0.5-0.5
Intermittent access intake day 1-15 change0.20.20.5-0.5-0.20.40.7-0.70.00.5-0.7-0.5-0.5-0.3
Intermittent access intake escalation1.01.02.4-0.00.40.50.0-0.0-0.91.0-1.6-1.5-1.5-1.3
Intermittent access intake escalation 21.01.02.5-0.5-0.11.00.4-0.4-0.41.3-1.6-1.5-1.3-1.0
Intermitt. access day 1 inactive lever presses0.80.92.10.10.50.5-0.10.1-0.91.0-1.5-1.4-1.4-1.3
Intermitt. access day 15 inactive lever presses0.80.92.1-0.7-0.41.10.5-0.5-0.11.3-1.4-1.3-1.1-0.8
Intermitt. access escalation Index1.21.11.8-0.5-0.6-0.31.1-1.11.1-0.91.21.31.31.3
Intermittent access day 1 total infusions0.20.30.60.50.5-0.8-0.30.3-0.1-0.80.60.60.40.2
Intermittent access day 15 total infusions0.10.20.40.40.6-0.4-0.20.2-0.5-0.2-0.2-0.2-0.5-0.4
Intermittent access terminal intake (last 3 days)0.20.20.70.20.3-0.70.2-0.20.1-0.80.60.60.30.4
Intermittent access total infusions0.20.20.60.60.7-0.8-0.40.4-0.5-0.60.20.2-0.2-0.1
Intermittent access day 1 locomotion0.00.00.00.10.10.0-0.00.0-0.10.1-0.1-0.1-0.0-0.2
Intermittent access day 15 total locomotion0.30.30.8-0.6-0.30.60.9-0.90.20.5-0.7-0.5-0.3-0.2
Intermittent access total locomotion0.20.20.4-0.6-0.50.50.6-0.60.50.3-0.1-0.00.20.2
Intermittent access standard deviation0.20.20.6-0.30.00.30.5-0.5-0.20.5-0.7-0.6-0.5-0.4
Left kidney weight0.51.43.1-0.0-0.2-0.70.3-0.31.1-1.41.71.81.51.6
Right kidney weight0.30.91.8-1.0-0.80.51.4-1.41.1-0.10.40.61.01.0
Cocaine induced anxiety1.61.83.5-1.6-1.81.11.6-1.61.90.30.60.81.41.4
Post-drug Anxiety1.82.03.8-1.0-1.20.21.1-1.11.8-0.81.51.71.92.0
Baseline Anxiety0.10.10.30.20.2-0.0-0.30.3-0.40.2-0.4-0.4-0.6-0.4
Tail length2.78.117.1-3.6-3.44.13.1-3.11.83.7-2.6-2.1-0.4-0.3
Length with tail0.93.46.7-2.5-2.62.62.1-2.11.82.0-0.9-0.60.50.6
Length without tail0.30.71.60.2-0.1-0.6-0.10.10.6-1.11.21.21.11.1
Times rat made contact with spout0.91.01.91.31.3-1.0-1.41.4-1.3-0.4-0.2-0.4-0.9-0.9
Lifetime Intake0.60.72.00.90.9-1.4-0.60.6-0.4-1.30.90.80.20.3
Liver weight, left1.01.63.61.71.9-1.5-1.51.5-1.6-0.90.1-0.1-0.8-0.8
Liver weight, right0.50.81.81.21.2-1.3-0.90.9-0.8-1.10.70.60.10.1
Locomotor activity2.53.97.7-2.5-2.82.22.6-2.62.31.3-0.10.31.41.4
Locomotor testing distance1.01.63.2-1.6-1.61.31.8-1.81.50.7-0.00.20.90.9
Locomotor testing rearing0.10.10.20.10.10.2-0.20.2-0.50.4-0.4-0.5-0.4-0.5
Locomotion in novel chamber0.10.20.50.50.7-0.6-0.30.3-0.5-0.50.10.1-0.2-0.2
Locomotion in novel chamber post-restriction2.02.44.9-2.1-1.92.22.0-2.01.51.6-1.0-0.70.20.2
Fecal boli incidents, locomotor time 11.01.12.31.11.1-0.4-1.31.3-1.50.1-0.6-0.9-1.2-1.2
Change in fecal boli incidents, locomotor task1.31.32.3-1.0-1.10.31.1-1.11.5-0.41.01.21.51.5
Time >=10cm from walls, locomotor time 10.80.82.00.50.3-0.9-0.30.30.3-1.41.41.31.01.1
Bouts of movement, locomotor time 10.30.30.7-0.7-0.60.80.6-0.60.30.7-0.6-0.5-0.1-0.2
Total resting periods, locomotor time 10.60.71.5-1.1-1.11.21.0-1.00.70.9-0.6-0.40.10.1
Rest time, locomotor task time 10.30.30.8-0.8-0.90.70.6-0.60.70.30.10.20.50.5
Distance moved, locomotor task time 10.90.92.00.50.4-1.3-0.10.10.3-1.41.41.41.01.1
Vertical activity count, locomotor time 10.70.71.81.21.3-1.3-0.80.8-0.9-0.80.20.1-0.4-0.4
Time >=10cm from walls, locomotor time 20.80.91.81.21.3-1.0-1.11.1-1.2-0.5-0.0-0.2-0.7-0.7
Bouts of movement, locomotor time 20.70.71.4-0.8-0.90.40.8-0.81.1-0.30.80.91.11.2
Total resting periods, locomotor time 20.90.91.8-0.7-0.90.30.8-0.81.2-0.51.01.11.31.3
Rest time, locomotor task time 20.40.40.9-0.4-0.50.10.4-0.40.8-0.50.80.91.01.0
Distance moved, locomotor task time 20.40.40.90.40.5-0.1-0.40.4-0.80.5-0.8-0.9-1.0-1.0
Vertical activity count, locomotor time 21.61.83.01.51.7-1.0-1.51.5-1.7-0.1-0.7-0.9-1.5-1.5
Light reinforcement 12.13.97.4-2.7-2.62.42.7-2.71.91.6-0.9-0.40.60.8
Light reinforcement 20.60.81.6-1.2-1.31.11.2-1.20.70.9-0.5-0.20.30.3
Bone: marrow area0.51.02.60.80.8-1.5-0.30.3-0.1-1.61.31.30.80.8
Bone: maximum diameter1.12.03.3-1.1-1.20.01.6-1.61.7-0.81.31.61.81.8
Bone: maximum force1.93.36.92.01.5-2.6-1.51.5-0.7-2.62.22.01.01.0
Bone: maximum moment1.93.26.81.91.5-2.6-1.51.5-0.6-2.62.22.01.01.0
Mean time between licks in bursts0.60.81.5-1.0-0.71.11.0-1.00.41.2-1.1-1.0-0.6-0.6
Mean num. licks in bursts0.60.71.2-1.1-1.10.91.1-1.10.90.5-0.10.10.60.6
Cd content in liver0.20.30.50.60.7-0.7-0.70.7-0.1-0.50.30.20.10.1
Co content in liver0.80.92.0-1.0-0.81.30.8-0.80.41.4-1.3-1.1-0.6-0.6
Cu content in liver1.21.53.60.70.7-1.6-0.30.30.3-1.91.71.71.21.2
Fe content in liver0.50.51.10.91.1-0.6-0.90.9-1.0-0.2-0.2-0.4-0.7-0.7
K content in liver0.80.81.3-0.9-0.90.41.0-1.01.1-0.10.60.81.11.1
Mg content in liver1.01.02.0-0.9-0.90.20.8-0.81.4-0.41.01.11.41.4
Mn content in liver3.13.56.8-1.2-1.4-0.01.5-1.52.2-1.32.12.42.62.6
Na content in liver0.20.20.70.1-0.1-0.3-0.20.20.2-0.60.80.80.60.6
Rb content in liver1.01.32.90.40.4-1.30.0-0.00.5-1.71.61.61.41.4
Se content in liver0.00.10.2-0.3-0.20.20.1-0.10.40.10.10.20.30.3
Sr content in liver1.00.92.1-0.10.10.60.1-0.1-0.81.0-1.4-1.4-1.3-1.3
Zn content in liver2.42.65.9-1.0-0.71.80.6-0.6-0.42.4-2.4-2.3-1.7-1.7
Bone: minimum diameter0.61.02.30.20.2-1.10.2-0.20.6-1.51.51.51.21.2
Time in familiar zone, hab. session 13.12.96.2-2.1-2.02.51.8-1.81.12.3-1.6-1.3-0.3-0.3
Time in novel zone, hab. session 12.82.76.31.61.4-2.3-1.21.2-0.2-2.52.12.01.21.2
Total zone transitions, hab. session 11.01.42.8-1.1-1.30.51.0-1.01.7-0.41.11.31.61.6
Total locomotion distance, hab. session 12.94.17.7-2.0-2.21.02.1-2.12.8-0.41.51.82.52.5
Locomotion velocity, hab. session 12.33.26.2-2.0-2.11.22.0-2.02.5-0.01.01.32.12.1
Time in familiar zone, hab. session 23.23.36.5-2.1-1.82.51.8-1.80.82.6-2.1-1.8-0.8-0.8
Time in novel zone, hab. session 23.73.77.72.11.8-2.7-1.71.7-0.6-2.82.32.01.01.0
Total zone transitions, hab. session 21.51.94.50.30.0-1.1-0.00.00.9-1.82.12.11.81.8
Total locomotion distance, hab. session 20.81.12.1-0.9-1.10.30.8-0.81.4-0.41.01.11.41.4
Locomotion velocity, hab. session 21.21.73.2-1.0-1.20.31.0-1.01.7-0.61.31.51.81.8
Novel to familiar place preference ratio2.62.66.11.41.2-2.0-1.21.2-0.1-2.52.22.01.31.3
Novelty place preference1.91.94.61.00.9-1.7-0.90.90.1-2.22.01.81.31.3
Time in novel zone, NPP test2.22.25.31.31.2-1.9-1.11.1-0.1-2.32.01.81.21.2
Total zone transitions, NPP test0.50.71.60.40.1-0.7-0.60.60.3-1.01.31.20.90.9
Total locomotion distance, NPP test0.70.92.0-0.1-0.4-0.40.0-0.00.9-1.01.41.41.41.4
Locomotion velocity, NPP test0.60.81.8-0.4-0.7-0.00.3-0.31.1-0.71.21.21.31.3
Intraocular pressure0.91.32.7-0.3-0.21.1-0.20.2-0.61.5-1.6-1.6-1.5-1.5
Delta distance traveled before/after self-admin0.00.00.10.10.1-0.30.2-0.2-0.1-0.30.30.30.30.2
Delta ambulatory time before/after self-admin0.20.30.60.0-0.0-0.40.3-0.30.3-0.60.70.80.80.6
Parametrial fat weight0.10.10.4-0.2-0.20.3-0.00.0-0.10.6-0.5-0.5-0.4-0.3
Pavlov. Cond. lever latency0.70.91.80.50.60.1-0.60.6-1.30.8-1.1-1.2-1.3-1.3
Pavlov. Cond. magazine entry latency0.91.22.2-1.4-1.21.51.3-1.31.01.3-0.9-0.7-0.1-0.1
Pavlov. Cond. change in total contacts0.10.10.50.30.5-0.6-0.10.10.1-0.70.40.40.20.2
Pavlov. Cond. index score0.60.71.7-0.9-0.90.60.9-0.91.3-0.10.40.60.90.9
Pavlov. Cond. latency score0.91.12.6-1.0-1.10.51.1-1.11.6-0.30.80.91.31.3
Pavlov. Cond. lever contacts1.11.32.6-0.4-0.6-0.20.4-0.41.4-1.11.51.51.61.6
Pavlov. Cond. magazine entry number0.30.40.70.90.7-0.8-0.80.8-0.8-0.60.30.2-0.1-0.1
Pavlov. Cond. intertrial magazine entries0.40.51.10.00.10.4-0.10.1-0.60.8-1.0-1.0-1.0-1.0
Pavlov. Cond. lever-magazine prob. diff.0.60.81.8-1.0-1.00.71.1-1.11.40.10.30.50.90.9
Pavlov. Cond. response bias0.40.51.0-1.0-0.90.90.9-0.91.00.6-0.3-0.20.30.3
Pavlov. Cond. lever latency0.91.22.41.51.5-1.5-1.31.3-1.0-1.20.60.4-0.2-0.2
Pavlov. Cond. magazine entry latency1.51.73.2-1.8-1.81.71.7-1.71.41.2-0.6-0.30.50.5
Pavlov. Cond. change in total contacts0.50.61.1-1.0-0.91.01.0-1.00.60.9-0.6-0.5-0.0-0.0
Pavlov. Cond. index score1.21.62.9-1.7-1.61.71.6-1.61.11.4-0.9-0.60.20.2
Pavlov. Cond. latency score1.41.73.2-1.8-1.71.71.6-1.61.31.3-0.6-0.30.40.4
Pavlov. Cond. lever contacts0.81.12.3-1.3-1.21.51.1-1.10.71.4-1.0-0.8-0.2-0.2
Pavlov. Cond. magazine entry number1.41.73.11.81.7-1.6-1.81.8-1.4-1.20.50.2-0.5-0.5
Pavlov. Cond. intertrial magazine entries0.81.12.01.31.3-0.9-1.41.4-1.4-0.3-0.2-0.4-0.9-0.9
Pavlov. Cond. lever-magazine prob. diff.1.31.73.2-1.8-1.71.71.7-1.71.31.3-0.7-0.40.30.3
Pavlov. Cond. response bias1.31.83.4-1.7-1.61.81.5-1.50.91.7-1.2-1.0-0.2-0.2
Time in closed arm before self-admin0.80.92.10.1-0.2-0.60.1-0.10.8-1.11.41.41.21.3
Time in closed arm after self-admin0.10.20.50.50.6-0.7-0.20.2-0.2-0.60.30.2-0.20.0
Time in open arm before self-admin0.30.40.9-0.5-0.10.50.7-0.7-0.00.7-0.9-0.8-0.5-0.6
Time in open arm after self-admin0.80.91.71.21.2-0.9-1.31.3-1.3-0.50.0-0.2-0.6-0.7
Bone: periosteal estimation1.22.66.20.90.7-2.0-0.30.30.4-2.52.32.31.61.6
Bone: periosteal perimeter1.01.73.2-0.4-0.5-0.70.9-0.91.3-1.41.61.81.81.8
Bone: post-yield work0.20.30.60.70.6-0.8-0.60.6-0.5-0.60.40.3-0.0-0.0
Progressive ratio test 1 active lever presses0.80.91.71.21.3-1.3-1.01.0-1.0-1.00.40.3-0.3-0.3
Progressive ratio test 1 breakpoint0.90.91.91.31.3-1.4-1.01.0-0.9-1.10.60.4-0.2-0.2
Progressive ratio test 1 inactive lever presses0.10.10.4-0.20.1-0.30.7-0.70.2-0.40.10.30.10.2
Progressive ratio test 2 active lever presses0.30.30.90.70.7-0.9-0.40.4-0.4-0.90.40.4-0.10.1
Progressive ratio test 2 breakpoint0.30.30.80.10.2-0.70.2-0.20.3-0.90.80.80.50.6
Progressive ratio test 2 inactive lever presses0.30.31.00.30.4-0.90.0-0.00.1-1.00.70.80.30.5
Incentive Sensitization - Responses0.10.10.2-0.4-0.30.20.4-0.40.20.1-0.1-0.00.00.1
Incentive Sensitization - Breakpoint0.20.20.4-0.5-0.40.30.6-0.60.50.00.00.20.30.4
Sum of active levers in priming session hrs 5-60.20.20.4-0.5-0.50.60.3-0.30.20.6-0.4-0.3-0.2-0.1
Progressive ratio0.70.91.61.31.3-1.2-1.11.1-1.2-0.70.2-0.0-0.5-0.5
Food seeking constrained by brief footshock0.91.13.0-1.4-1.41.71.0-1.00.91.3-0.7-0.60.00.1
Seeking ratio, punishment vs. effort1.31.63.8-1.7-1.72.01.3-1.31.31.4-0.7-0.60.20.2
Retroperitoneal fat weight1.65.19.53.13.0-2.8-3.03.0-2.4-1.90.80.3-1.0-0.9
Reaction time number correct1.11.63.11.41.4-0.8-1.71.7-1.7-0.1-0.5-0.8-1.2-1.3
Reaction time mean minus median0.91.22.6-1.4-1.61.41.3-1.31.11.2-0.4-0.20.40.4
Reaction time mean minus median AUC1.92.54.6-1.7-2.01.01.8-1.82.10.20.91.21.81.7
Reaction time num false alarms0.50.61.31.01.0-0.9-1.11.1-1.0-0.50.1-0.1-0.5-0.5
Reaction time num false alarms AUC0.71.01.91.21.2-0.8-1.41.4-1.3-0.3-0.2-0.4-1.0-0.8
Reaction time trials correct on left1.11.63.11.41.4-0.8-1.71.7-1.7-0.1-0.5-0.8-1.2-1.3
Reaction time trials on left1.01.42.71.41.4-0.8-1.61.6-1.7-0.1-0.4-0.7-1.1-1.2
Reaction time mean1.11.63.2-1.5-1.61.11.5-1.51.80.30.40.61.31.2
Reaction time mean AUC0.71.02.1-1.1-1.10.61.1-1.11.5-0.10.60.81.21.1
Median of all reaction times0.71.02.3-1.1-1.10.71.2-1.21.5-0.00.50.71.21.1
Reaction time omissions0.10.10.3-0.1-0.1-0.10.4-0.40.4-0.40.40.50.50.4
Reaction time false alarm rate0.10.10.20.40.3-0.5-0.40.4-0.2-0.40.30.30.00.1
Reaction time premature initiation rate1.21.63.6-1.1-0.91.70.9-0.9-0.01.9-1.7-1.6-0.9-0.9
Reaction time premature initiations1.31.84.2-0.3-0.11.3-0.00.0-1.01.9-2.0-2.0-1.6-1.7
Std. dev. reaction times0.71.01.8-1.3-1.30.91.2-1.21.40.40.20.40.90.8
Reaction time trials completed1.01.42.71.41.4-0.8-1.61.6-1.7-0.1-0.4-0.7-1.1-1.2
Reaction time trials AUC1.31.83.61.51.5-0.8-1.81.8-1.9-0.0-0.6-0.9-1.3-1.4
Run reversals in cocaine runway, females1.51.42.4-1.5-1.61.31.5-1.51.50.8-0.00.21.01.0
Run reversals in cocaine runway, males1.91.94.0-1.8-1.61.42.0-2.01.60.5-0.00.30.90.9
Latency to leave start box in cocaine runway1.21.22.9-0.1-0.5-0.70.2-0.21.1-1.21.71.71.51.5
Latency to leave start box in cocaine runway, F2.32.55.7-0.1-0.6-0.90.4-0.41.5-1.82.42.42.22.2
Latency to leave start box in cocaine runway, M0.60.51.00.30.20.0-0.50.5-0.90.8-0.9-1.0-1.0-1.0
Std. dev. time between licks in bursts1.01.22.0-1.0-1.00.41.4-1.41.3-0.30.81.01.31.3
Total sessions with >9 infusions1.31.53.10.0-0.0-1.20.7-0.70.9-1.71.61.81.31.5
Short access day 1 total inactive lever presses0.00.00.1-0.00.1-0.30.3-0.3-0.0-0.30.10.20.00.2
Short access day 10 total inactive lever presses0.40.41.00.20.50.0-0.10.1-0.70.5-1.0-0.9-1.0-0.9
Short access day 1 total infusions1.71.84.60.50.4-1.70.3-0.30.5-2.11.92.01.31.5
Short access day 10 total infusions0.40.51.40.80.9-1.2-0.30.3-0.4-1.10.60.60.10.1
Short access total infusions1.61.85.01.00.9-2.0-0.40.4-0.0-2.21.81.80.91.1
Short access day 1 locomotion0.40.40.8-0.4-0.4-0.20.9-0.90.7-0.50.60.70.90.7
Short access day 10 total locomotion1.21.32.1-1.3-0.81.51.4-1.40.41.5-1.4-1.2-0.5-0.5
Short access total locomotion0.20.30.8-0.6-0.40.20.9-0.90.5-0.00.10.20.40.4
One hour access (0.3 mA shock)0.20.30.60.70.6-0.7-0.60.6-0.4-0.70.30.2-0.2-0.0
Compulsive drug intake0.20.20.30.50.3-0.5-0.60.6-0.3-0.50.40.30.00.1
One hour access (shock baseline)0.20.20.40.40.6-0.3-0.20.2-0.70.1-0.5-0.5-0.7-0.6
Social response proportion0.70.71.5-1.1-1.21.11.0-1.01.00.40.20.30.70.7
Social responses5.97.614.9-3.7-3.93.43.5-3.53.02.3-0.6-0.11.51.5
Social time0.70.91.91.41.2-1.1-1.21.2-1.2-0.60.2-0.0-0.5-0.5
Soleus weight3.911.420.94.64.3-4.4-4.44.4-3.3-3.41.91.2-0.7-0.7
Bone: stiffness2.74.39.42.52.2-3.1-2.12.1-1.3-2.82.11.80.50.5
Tibialis anterior weight0.82.74.92.22.1-2.1-2.22.2-1.5-1.71.00.6-0.3-0.3
Time to tail flick, vehicle, before self-admin2.82.84.9-1.7-1.70.62.2-2.22.2-0.41.11.41.82.0
Time to tail flick, vehicle, after self-admin0.60.61.4-0.2-0.10.8-0.20.2-0.31.1-1.2-1.2-0.9-1.0
Time to tail flick, test, before self-admin1.61.53.2-1.3-1.30.61.4-1.41.8-0.20.81.01.51.4
Time to tail flick, test, after self-admin0.70.81.5-0.5-0.7-0.10.7-0.71.0-0.61.01.11.21.2
Delta time to tail flick, vehicle, before/after SA2.62.64.51.41.4-0.3-2.12.1-1.90.7-1.2-1.5-1.8-2.0
Delta time to tail flick, test, before/after SA0.40.40.8-0.0-0.00.5-0.20.2-0.60.8-0.8-0.9-0.8-0.7
Tibia length0.61.73.5-1.6-1.61.91.2-1.20.91.9-1.1-0.9-0.2-0.2
Ambulatory time before self-admin0.10.20.4-0.6-0.60.50.5-0.50.40.4-0.2-0.10.00.2
Ambulatory time after self-admin0.10.10.1-0.3-0.30.10.4-0.40.10.00.20.20.30.3
Bone: tissue strength2.52.45.32.01.8-2.3-1.61.6-1.1-2.01.41.20.20.2
Total heroin consumption1.51.73.5-1.8-1.91.71.6-1.61.51.1-0.3-0.10.70.7
Bone: trabecular number1.42.23.8-1.4-1.70.61.4-1.41.9-0.41.31.51.91.9
Bone: trabecular spacing2.73.57.01.01.50.1-1.31.3-2.21.4-2.3-2.5-2.6-2.6
Bone: trabecular thickness5.26.313.2-0.6-1.1-1.21.2-1.22.5-2.73.53.63.53.5
Bone: trabecular tissue density4.05.610.53.23.2-2.8-3.03.0-2.8-1.70.4-0.1-1.4-1.4
Water consumed over 24 hours1.01.12.70.70.5-1.3-0.30.30.2-1.61.61.51.11.1
Number of responses in last shaping day0.60.71.9-1.1-0.80.81.4-1.40.70.6-0.5-0.20.20.2